Regeneration and Repair

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    REGENERATION AND REPAIR

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    HORMONES = estrogen, progesterone, somatotropin, insulin

    EGF bFGFPDGF VEGF

    IL-1 and IL-2 TNF

    TIGF NGF

    Macrophage Derived Growth Factors

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    SEEN IN: Cell Surfaces, Basement Membranes and

    Pericellular Matrices

    MADE BY: Fibroblasts, Endothelial Cells and Monocytes

    IN WOUND HEALING

    Facilitate migration of epithelium

    Chemotactic for monocytes

    Chemotactic for fibroblasts

    Stimulate endothelial migration and

    organization

    Release bFGF from monocytes

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