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Transcript of Public Health Surveillance Systems. Goals Review purpose of surveillance Describe types of state and...
Public Health Surveillance Systems
Goals Review purpose of surveillance Describe types of state and local
surveillance systems: Vital records Disease reporting
(morbidity data) Surveys Sentinel surveillance Zoonotic disease
surveillance Provide example of public health actions
resulting from surveillance data
Adverse events surveillance
Syndromic surveillance
Registries Laboratory data
Purpose of Surveillance Collecting surveillance data has many
purposes Monitoring disease trends Detecting outbreaks Providing information to plan public health
interventions Stimulating research
Purpose of Surveillance Specific uses of surveillance data vary
depending on organization or agency National agencies
Monitoring disease trends over time to inform policy
State and local agencies Assuring accurate diagnosis and treatment
of infected persons Managing people exposed to disease Detecting outbreaks Guiding public health prevention and
control programs
Types of State and Local Surveillance Systems Surveillance systems used to monitor
disease trends and plan public health programs Vital statistics, disease reporting, surveys
More specialized systems Sentinel surveillance, zoonotic disease
surveillance, adverse events surveillance, syndromic surveillance, disease registries, laboratory surveillance
Some types more useful for certain diseases than others; each fills a specific need
Vital Statistics Records of births and deaths: a basic but critical
cornerstone of public health surveillance Mortality data over past century show decrease in
rate of deaths due to infectious diseases; rate of death from non-infectious causes remain steady
Infant mortality rate (number of deaths among infants per 1,000 births) long used as indicator of overall population health
Birth data used to monitor incidence of preterm birth, risk factor for variety of adverse health outcomes
Vital Statistics In United States, vital statistics available
from National Center for Health Statistics State vital records offices CDC WONDER – online system containing
data on births, deaths, many diseases from Centers for Disease Control and Prevention (CDC)
Disease Reporting (Morbidity Data) Disease reporting required internationally
by World Health Organization through International Health Regulations Smallpox Wild-type poliomyelitis Severe acute respiratory syndrome (SARS) Human influenza caused by new subtypes Any public health emergency of international
concern Broad definition used to capture any disease,
condition, event that could represent international risk
Disease Reporting (Morbidity Data) In the United States, disease reporting
mandated by state law List of reportable diseases varies by state
States report nationally notifiable diseases to CDC on voluntary basis List of notifiable diseases updated regularly
by Council of State and Territorial Epidemiologists and CDC
Surveys Especially useful for monitoring chronic
diseases and health-related behaviors Youth Risk Behavior Survey (YRBS) asks
high school students about substance use, sexual behavior, physical activity, nutrition
Results used to monitor trends in health behaviors, plan public health programs, evaluate public health policies at national and state levels
Surveys YRBS
shows decline in youth smoking from 36% in 1997 to 20% in 2007
20%23%22%
29%
35%36%
0
10
20
30
40
50
1997 1999 2001 2003 2005 2007Year
Perc
en
t
Percent of high school students who reported smoking in the 30 days prior to the survey,
United States, 1997-2007
Surveys Other national surveys conducted by
CDC: Behavioral Risk Factor Surveillance System
(BRFSS) National Health Interview Survey (NHIS) Pregnancy Risk Assessment Monitoring
System (PRAMS) National Health and Nutrition Examination
Survey (NHANES)
Sentinel Surveillance Alternative to population-based
surveillance, Involves collecting data from sample of
reporting sites (sentinel sites) Example: Selected health care providers
report number of cases of influenza-like illness to state health department on weekly basis
Allows states to monitor trends using relatively small amount of information
Sentinel Surveillance Graph
indicates peak of influenza activity during 2007- 2008 season in late February and early March (Weeks 7-9)
Percentage of visits for influenza-like illness reported by US sentinel provider network,
2006-2007, 2007-2008
Sentinel Surveillance Sentinel providers also used to gather
more specific information Example: sentinel provider network in
British Columbia, Canada, used in a study of vaccine effectiveness during 2005-2006 influenza season
Zoonotic Disease Surveillance Surveillance of zoonotic diseases (diseases
found in animals that can be transmitted to humans) often involves system for detecting infected animals
Example: 2001 Florida surveillance for West Nile Virus (WNV):
Web site and telephone hotline to report dead birds, some collected and tested for WNV
Mosquitoes collected and tested for WNV in 10 counties Blood collected from 3-12 sentinel chickens in each of
212 flocks up to 4 times per month, tested for antibodies to WNV
Veterinarians asked to test horses with neurologic symptoms consistent with WNV
Health care providers reminded of reporting and diagnostic criteria for possible human cases of WNV
Zoonotic Disease Surveillance Surveillance systems allowed public
health authorities to determine intensity of WNV by geographic area
Detection of WNV led to public health control measures: Advising public to protect against mosquito
bites Intensifying mosquito abatement efforts
Adverse Events Surveillance Surveillance system focusing on patient
safety: Adverse Events Reporting System (AERS), operated by Food and Drug Administration (FDA)
Negative effects experienced by people who received approved drugs, therapeutic agents
Voluntary reports from health care providers (physicians, pharmacists, nurses) and public (patients, lawyers)
Health care providers/patients may report events directly to product manufacturer; manufacturer required to report event to AERS
FDA uses AERS to identify possible safety concerns associated with approved products
Adverse Events Surveillance Vaccine Adverse Events Reporting
System (VAERS) also focused on patient safety; operated by CDC with FDA Like AERS, but for negative effects
experienced by people who have received licensed vaccines
Used in 2003 for smallpox vaccines to health care and public health professionals in preparation for bioterrorist attack
>100 adverse events reported after smallpox vaccination, 16 suspect and 5 probable cases of myocarditis or pericarditis
Advisory Committee on Immunization Practices recommended ending vaccination after health care and public health response teams
Adverse Events Surveillance Passive surveillance systems may be
limited by underreporting or biased reporting, cannot be used to determine whether a drug or vaccine caused a specific adverse health event (See FOCUS Volume 5, Issue 5 for definitions
of active and passive surveillance) Used as early warning signals Possible associations between drugs or
vaccines and adverse events examined using well designed epidemiologic study, appropriate action based on results
Syndromic Surveillance Relatively new surveillance method, uses
clinical information about disease signs and symptoms, before diagnosis is made
Often use electronic data from hospital emergency rooms
Syndromic Surveillance Example: New York City operates
syndromic surveillance system using emergency department chief-complaint data from approximately 44 hospitals Data monitored electronically for beginning
of disease outbreak In 2002, system detected higher than usual
number of diarrheal and vomiting symptoms Health department notified hospital
emergency departments of possible outbreak and collected stool specimens, several tested positive for norovirus
Syndromic Surveillance Example: New York City (continued)
Similar outbreak later that year not detected by the system
Failure to detect attributed to incorrect coding of chief complaint by emergency departments
Illustrates potential benefits of syndromic surveillance, areas where changes needed to increase usefulness of system
Registries Surveillance system used for particular
conditions Often established at state level to collect
information about persons diagnosed with condition Example: cancer registries collect
information about type of cancer, anatomic location, stage of disease at diagnosis, treatment, outcomes
Used to improve prevention programs Example: women in rural areas diagnosed
with breast cancer later than women in urban areas; choose to promote mammography screening in rural areas using mobile van
Laboratory Data Public health laboratories routinely conduct
tests for viruses, bacteria, other pathogens In US, labs participate in National Salmonella
Surveillance System through electronic reporting of Salmonella isolates
2006: >40,000 isolates reported Lab serotyping provides information about
cases likely to be linked to common source Serotypes are useful for detecting local,
state, or national outbreaks
Laboratory Data Another lab system: PulseNet by CDC and
Association of Public Health Laboratories to monitor foodborne illness outbreaks Enables labs across US to compare pulsed-
field gel electrophoresis (PFGE) patterns of bacteria from ill persons and determine similarity
Allows scientists to determine whether outbreak is occurring, even at geographically distant locations
Can decrease time required to identify outbreaks of foodborne illness and causes
Public Health Actions Resulting From Surveillance: Poliomyelitis
Global example: monitoring progress toward eradication of poliomyelitis
Number of cases of paralytic poliomyelitis by year, United States,
1967-1997
Dramatic decrease in paralytic poliomyelitis in US following licensure of inactivated polio vaccine (1955), oral polio vaccine (1961)
Public Health Actions Resulting From Surveillance: Poliomyelitis
Global example: monitoring progress toward eradication of poliomyelitis (continued) Using data from countries around world, World
Health Organization implemented intensive vaccination programs where decline not as significant
Public Health Actions Resulting From Surveillance: HIV/AIDS Example: surveillance for HIV/AIDS ongoing
since detection of disease in the US in 1981 Data on incidence and prevalence among
population subgroups, geographic areas important to guide prevention, control efforts 2003-2006: estimated number of cases increased
among men who have sex with men, remained steady among heterosexuals, decreased among injection drug users
Suggests that prevention programs working more effectively in some groups than others
Public Health Actions Resulting From Surveillance: HIV/AIDS Mapping rates
shows clear pattern of higher risk in southeastern states than in rest of nation
Suggests need for more prevention measures in southeast
Rates of diagnosed HIV/AIDS, by area of residence, United States, 2006
Conclusion Many sources of public health surveillance
data at local, state, national levels Knowing where to look for different types
of data can save time and resources Data used for variety of purposes:
Guiding prevention strategies and targeting resources
Detecting disease outbreaks of local, national, international significance
Evaluating control measures
Resources National Vital Statistics System
Data on births, deaths, marriages, divorces, fetal deaths from all 50 states, 2 cities (Washington, DC, and New York City), 5 territories (Puerto Rico, Virgin Islands, Guam, American Samoa, Commonwealth of the Northern Mariana Islands); much of information available online
http://www.cdc.gov/nchs/nvss.htm CDC WONDER
User-friendly query system providing public health information on births, deaths, cancer incidence, HIV and AIDS, tuberculosis, vaccinations, census data
http://wonder.cdc.gov/ Nationally Notifiable Infectious Diseases
List of diseases recommended for states to report to CDC
http://www.cdc.gov/ncphi/disss/nndss/phs/infdis.htm
References1. Birkhead GS, Maylahn CM. State and local public health
surveillance. In: Teutsch SM, Churchill RE, eds. Principles and Practice of Public Health Surveillance. 2nd ed. New York, NY: Oxford University Press; 2000:253-286.
2. Armstrong GL, Conn LA, Pinner RW. Trends in infectious disease mortality in the United States during the 20th century. JAMA. 1999;281(1):61-66.
3. World Health Organization. International health regulations (2005). 2nd ed. http://www.who.int/csr/ihr/en/. Published 2008. Accessed October 3, 2008.
4. Centers for Disease Control and Prevention. Summary of notifiable diseases – United States, 2006. Morb Mortal Wkly Rep. 2008;55(53):1-84.
5. Centers for Disease Control and Prevention. Cigarette use among high school students – United States, 1991-2007. Morb Mortal Wkly Rep. 2008;57(25):689-691.
References6. FluView. Outpatient illness surveillance. Centers for
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9. Food and Drug Administration, Center for Drug Evaluation and Research. Adverse Event Reporting System (AERS) Web site. http://www.fda.gov/cder/aers/default.htm. Published August 7, 2002. Updated September 5, 2008. Accessed November 21, 2008.
References10. Zhou W, Pool V, Iskander JK, et al. Surveillance for
safety after immunization: vaccine adverse events reporting system (VAERS) – United States, 1991-2001. MMWR CDC Surveill Summ. 2003;52(SS-1):1-11.
11. Centers for Disease Control and Prevention. Update: adverse events following civilian smallpox vaccination – United States, 2003. Morb Mortal Wkly Rep. 2004;53(5):106-107.
12. Centers for Disease Control and Prevention. Advisory Committee on Immunization Practices (ACIP) statement on smallpox preparedness and vaccination. http://www.bt.cdc.gov/agent/smallpox/vaccination/acipjun2003.asp. Published June 18, 2003. Accessed October 23, 2008.
13. Steiner-Sichel L, Greenko J, Heffernan R, Layton M, Weiss D. Field investigations of emergency department syndromic surveillance signals – New York City. Morb Mortal Wkly Rep. 2004;53(suppl):190-195.
References14. Centers for Disease Control and Prevention. Salmonella
surveillance: annual summary, 2006. http://www.cdc.gov/ncidod/dbmd/phlisdata/salmonella.htm. Published 2008. Accessed October 14, 2008.
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16. Centers for Disease Control and Prevention. What is PulseNet? PulseNet Web site. http://www.cdc.gov/pulsenet/whatis.htm. Published July 24, 2006. Accessed December 3, 2008.
17. Centers for Disease Control and Prevention. Summary of notifiable diseases, United States, 1997. Morb Mortal Wkly Rep. 1998;46(54):1-87.
18. Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report, 2006. Vol. 18. http://www.cdc.gov/hiv/topics/surveillance/resources/reports/. Published 2008. Accessed October 14, 2008.