Protein synthesis simulation
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Transcript of Protein synthesis simulation
Protein synthesis simulation
Today, we will turn the classroom into a working cell analogy!
Essential Question
How do we make a protein from DNA?
Our goals
Activity goal:As a group, you will build a
“protein.” (It will be something you can take home!)
Learning goal:To understand how protein
synthesis works.
Norms
No one of us is as smart as all of us together.
Help other group members without doing their work for them.
Every member of the group must carry out their own role.
Multiple abilities needed for your group to be successful
Ask questions that make your group members think more deeply about the science.
Connect the activity to what really happens in a cell.
Follow detailed instructions and catch mistakes. Develop a work plan. Organize your group so that your group can
follow the work plan. Make sure that all group members get a chance
to contribute their thoughts. Ask clarifying questions. Reflect on the work done during the activity.
Productive Team Work
What we’re listening and looking for:
Each group member is following their own role.
Each group member is contributing to completing the task.
Each group member is following safety rules. (GOGGLES OVER YOUR EYES!)
Your Group Role (10)DNA
Strand #
1 2 3 4 5 6 7
mRNA Luis L. Dashawn
David Kevin Bleivis Caralina
Mario
tRNA Kiola Brigitte Sergio Jazmin Karla Genaro Jose
Small Ribosoma
lSubunit
Colby Luis N. Stepha-nie A.
Mele Kiabet Veronica
Ashley
Large Ribosomal Subunit
Ofa Noah Chris Jonathan
Christina
Stepha-nie L.
*RM = mRNA TM = tRNA Recorder = Small Ribo- Facilitator = Large Ribo-
Step 1 : Familiarize yourself with your role
Read your own role. Make sure you understand what you are doing.
Step 2 : Familiarize your group with your role
Read out your role to your group members. Make sure they know what you are doing.
Wear your “nametag” after you’re done reading.
Stick to your role!tRNAs, mRNAs, and ribosomal
subunits all do different jobs in the cell. They can’t transform into each other.Ex) Only ONE group member (tRNA)
should be out of their seat retrieving materials.
ProceduresFollow the instructions. You will probably complete up to step
#5 today.Tomorrow…Build your protein.Clean up.Answer analysis questions in
COMPLETE SENTENCES and hand in.
Day 2Remember our essential question?
Essential Question
How do we make a protein from DNA?
Day 2Remember our essential question.Remember our goals?
Our goals
Activity goal:As a group, you will build a
“protein.” (It will be something you can take home!)
Learning goal:To understand how protein
synthesis works.
Day 2Remember our essential question &
goals.Finish translation (step #5).Build your protein, using your
translated instructions.Clean up!Answer analysis questions in
COMPLETE SENTENCES and hand in.
Lab Tips
EVERYONE in the group should help decode the DNA and mRNA strands.
READ LABELS CAREFULLY! Some “amino acids” will be your measuring equipment, others will be substances to add into your measuring equipment.
Clean Up!
Rinse out all used materials.Return materials to counter
(threonine and phenylalanine).Ask for plastic bags if you want
to take your protein home.mRNA: Return role cards and
Protein Synthesis Table to demo desk.