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CURRICULUM VITAE

Prof. Dr. Yılmaz Çapan

Hacettepe University, Faculty of Pharmacy Department of Pharmaceutical Technology 06100 Sıhhiye/Ankara-TURKEY E-mail: ycapan@hacettepe.edu.tr Phone: 0 312 310 1524 Fax: 0 312 311 4777

Education

1978 Ph.D. Pharmaceutical Technology, University of Lille II, Lille, France Thesis Title: Elaboration of Optimization Criteria on the Fabrication of Tablets

1978 M.Sc. Biopharmaceutics, University of Lille II, Lille, France

1976 M.Sc. Industrial Pharmaceutical Technology, University of Lille II, Lille, France

1972 B.Sc. (Pharm.) Hacettepe University, Faculty of Pharmacy, Ankara, Turkey

ProfessionalExperiences

2007 – 2009

Head of Department Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey

2007-

Head of FATUM Hacettepe University, Pharmaceutical and Biopharmaceutical Sciences Technology Application and Research Center (FATUM)

1990-

Professor Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey

1985-1990

Associate Professor Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey

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1979-1985

Assistant Professor Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Ankara, Turkey

April- July 2006 Visiting Professor,University of Kentucky,College of Pharmacy, Department of Pharmaceutical Sciences Lexington, KY 40536-0082,U.S.A.

April- July 2004 Visiting Professor,University of Kentucky,College of Pharmacy, Department of Pharmaceutical Sciences Lexington, KY 40536-0082,U.S.A.

April-August 2002

Visiting Professor,University of Kentucky,College of Pharmacy, Department of Pharmaceutical Sciences Lexington, KY 40536-0082,U.S.A.

April-June 2001 Visiting Professor ( Lecturing and research ) Louis Pasteur University, Faculty of Pharmacy, 67401 Strasbourg - France.

1998-1999 Visiting Professor,University of Kentucky,College of Pharmacy, Department of Pharmaceutical Sciences Lexington, KY 40536-0082,U.S.A.

October-November 1996

Visiting scientist in Professor D. Duchene’s Laboratory, Faculty of Pharmacy, University Paris-Sud, Chatenay-Malabry, Paris- France.

February-July 1995 Visiting Professor ( Lecturing and research ) Louis Pasteur University, Faculty of Pharmacy, 67401 Strasbourg - France.

February-August 1994

Visiting Professor ( Lecturing and research ) Louis Pasteur University, Faculty of Pharmacy, 67401 Strasbourg - France.

June 1993 Visiting scientist in Professor D. Duchene’s Laboratory, Faculty of Pharmacy, University Paris-Sud, Chatenay-Malabry, Paris- France.

June 1992 Visiting scientist in Professor D. Duchene’s Laboratory, Faculty of Pharmacy, University Paris-Sud, Chatenay-Malabry, Paris- France.

November 1990- March 1991

Visiting Professor ( Lecturing and research ) Louis Pasteur University, Faculty of Pharmacy, 67401 Strasbourg - France.

May-July 1990 Visiting scientist in Professor F. Puisieux's Laboratory Faculty of Pharmacy, University Paris- Sud, Chatenay-Malabry, Paris - France.

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May-July 1989 Visiting scientist in Professor D. Duchene’s Laboratory, Faculty of Pharmacy, University Paris-Sud, Chatenay-Malabry, Paris- France.

1982-1983 Visiting Scientist in Professor M. Traisnel's Laboratory, Faculty of Pharmacy, University of Lille II 59000 Lille- France.

Research Interests

• Tabletting • Sustained Release Oral Solid Dosage Forms • Bioadhesion • GMP and Quality Assurance • Protein Delivery from Biodegradable Microspheres • Brain Drug Targeting • Nanotechnology • QbD

Thesis Supervised

• Ph. D. Thesis

Sevda Şenel, Ph. D. (1989) Formulation and In Vitro Evaluation of Sustained Release Potassium Chloride Tablets

Sibel Bozdağ, Ph.D. (2003) Design and Evaluation of Mitoxantrone Loaded Microparticular Systems for the Treatment of Brain Tumors.

Yeşim Aktaş, Ph.D. (2005) Preparation of Nanoparticulate Delivery Systems for Brain Targeting of Caspase Inhibitors.

Meltem Çetin, Ph. D. (2006) Preparation and In vitro/in vivo Evaluation of Biotin Conjugate System of Salmon Calcitonin for Oral Application.

Meral Yüce, Ph. D. (2013) Quality by design application to immediate release candesartan cilexetil tablet formulation

Fırat Yerlikaya, Ph. D. (2013) Development of Paclitaxel Nanoparticles Using Quality-by-Design Approach

Seçil Çaban, Ph. D. (2016) Development of nanoparticle formulations for treatment of glioma, evaluation of in vitro and in vivo efficiacy

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Adem Şahin, Ph. D. (2017) Cellular uptake kinetics and mechanism of polymeric nanoparticles depending on particle size

Serhat Kozlu, Ph. D. (2017)

Sedenay Akbaş Ph. D

Gözde Ultav Ph. D

Hayrettin Tonbul Ph.D. İndrit Seko Ph. D.

Formulation Development, Optimisation and

In Vitro Evaluation of Nanoparticles

Effective to Bone Methastasis

In progress…

In progress…

In progress…

In progress…

• M.Sc. Thesis

Nurşen Ünlü, M.Sc. (1981) Formulation Studies of Wetting Solutions for Hard Contact Lenses.

Türkan Eldem, M. Sc. (1982) Formulation Studies on Sustained Release

Nitrofurantoin Tablets

Kadriye Çiftçi, M.Sc. (1988) Formulation and In Vitro- In Vivo Evaluation of Sustained Release Lithium Carbonate Tablets.

Şule Anlar, M.Sc. (1992) Formulation and In Vitro- In Vivo Evaluation of Mucoadhesive Morphine Sulfate Tablets.

Farhad S.Farshi, M.Sc.(1993) Formulation and Bioavailability of Conventional and Controlled Release Furosemide Tablets.

Buket Taylan, M. Sc. (1994) Formulation and In Vitro- In Vivo Evaluation of Bioadhesive Tablets Propranolol Hydrochloride

Yonca Yazıksız, M.Sc. (1996) Captopril Buccal Drug Delivery Systems.

Gülcan İkinci, M.Sc. (1997) Carbamazepin Buccal Drug Delivery Systems.

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Meltem Çetin, M.Sc. (2003) Preparation and Characterization of Basic Fibroblast Growth Factor (bFGF) loaded Microparticulate Drug Delivery Systems.

Cihan Kılıç, M.Sc. (2004) Preparation and Characterization of Nanoparticulate Systems for The Delivery of Antisense Oligonucleotides

Onur Pınarbaşlı, M.Sc. (2008)

Preparation of Alpha-phenyl-n-tert-butyl nitrone (PBN) loaded nanoparticulate delivery systems and evaluation of in vitro properties

N. Tuğba Tercan, M.Sc. (2009)

Advanced Technology: Regulatory Requirements During the Development and Marketing Phase of Nanotechnology Medicines

Seçil Çaban, M.Sc. (2010)

Preparation of Caspase Inhibitors and Basic Fibroblast Growth Factor (bFGF) Loaded Nanoparticles, Evaluation of Transition and Efficiency to the Brain Tissue

Serhat Kozlu, M.Sc. (2010)

Aquaporin-4 Antisense Oligonucleotide Loaded, Brain Targetted Nanoparticular System Design Against Cytotoxic Brain Eudema

Kıvılcım Öztürk, M.Sc. (2010) Design and Evaluation of Nanoparticle Carrier Systems Containing Free Radical Scavenger Substance

Gözde Aygül, M.Sc. (2011) Formulation and in vitro evaluation of nanoparticles containing paclitaxel

Dila Babat, M.Sc. (2013) Formulations and in vitro evaluation of nanoparticles containing docetaxel

Sevda Şahan, M. Sc.(2018) Formulation and in vitro evaluation of Donepezil loaded PLGA nanoparticles

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Publications

Journal Articles (International Scientific Journals)

• Kozlu, S., Sahin, A., Ultav, G., Yerlikaya, F., Calis, S., Capan, Y. Development and in vitro evaluation of doxorubicin and celecoxib co-loaded bone targeted nanoparticles. Journal of Drug Delivery Science and Technology, 45, pp. 213-219, 2018.

• Yemisci, M., Caban, S., Fernandez-Megia, E., Capan, Y., Couvreur, P., Dalkara, T. Preparation and characterization of biocompatible chitosan nanoparticles for targeted brain delivery of peptides, Methods in Molecular Biology, 1727, pp. 443-454, 2018.

• Sahin, A., Esendagli, G., Yerlikaya, F., Caban-Toktas, S., Yoyen-Ermis, D., Horzum, U., Aktas, Y., Khan, M. Couvreur, P., Capan, Y. A small variation in average particle size of PLGA nanoparticles prepared by nanoprecipitation leads to considerable change in nanoparticles’ characteristics and efficacy of intracellular delivery, Artificial Cells, Nanomedicine and Biotechnology 45 (8), pp 1657-1664, 2017

• Sahin, A., Yoyen-Ermis, D., Caban-Toktas, S., Horzum, U., Aktas, Y., Couvreur, P.,Esendagli, G., Capan, Y. Evaluation of brain-targeted chitosan nanoparticles through blood–brain barrier cerebral microvessel endothelial cells, Journal of Microencapsulation, 34 (7), pp 659-666, 2017

• Yuce, M., Capan, Y. Development and Validation of HPLC analytical methods used for determination of assay, content uniformity and dissolution of immediate release candesartan cilexetil 32 mg tablets. Acta Poloniae Pharmaceutica - Drug Research, 74(2), pp. 357-367, 2017.

• Sahin, A., Esendagli, G., Yerlikaya, F., Caban-Toktas, S., Yoyen-Ermis, D., Horzum, U., Aktas, Y., Khan, M., Couvreur, P., Capan, Y. A small variation in average particle size of PLGA nanoparticles prepared by nanoprecipitation leads to considerable change in nanoparticles’ characteristics and efficacy of intracellular delivery. Artificial Cells, Nanomedicine and Biotechnology, pp. 1-11, 2017.

• Yuce, M., Guven, O., Karahan, S., Saracbasi, O., Capan, Y. Preformulation of Immediate Release Candesartan Cilexetil Tablets Using Full Factorial Experimental Design. Lat. Am. J. Pharm. 35 (5): 921-30, 2016.

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• Yemisci M, Caban S, Gursoy-Ozdemir Y, Lule S, Novoa-Carballal R, Riguera R, Fernandez-Megia E, Andrieux K, Couvreur P, Capan Y, Dalkara T. Systemically administered brain-targeted nanoparticles transport peptides across the blood–brain barrier and provide neuroprotection. J Cereb Blood Flow Metab 35(3): 469-475, 2015.

• Gaudin A, Yemisci M, Eroglu H, Lepetre-Mouelhi S, Turkoglu OF, Dönmez-Demir B, Caban S, Sargon MF, Garcia-Argote S, Pieters G, Loreau O, Rousseau B, Tagit O, Hildebrandt N, Le Dantec Y, Mougin J, Valetti S, Chacun H, Nicolas V, Desmaële D, Andrieux K, Capan Y, Dalkara T, Couvreur P. Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury. Nature Nanotechnology, 9, 1054–1062, 2014.

• Kozlu, S., Caban, S., Yerlikaya, F., Fernandez-Megia, E., Novoa-Carballal, R.,

Riguera, R., Yemisci, M., Gursoy-Ozdemir, Y., Dalkara, T., Couvreur, P., Capan, Y., An Aquaporin 4 Antisense Oligonucleotide Loaded, Brain Targeted Nanoparticulate System Design. Pharmazie,69(5):340-5, 2014.

• Ozturk, K., Fernandez-Megia, E., Novoa-Carballal, R., Riguera, R., Yemisci, M.,

Gursoy-Ozdemir, Y., Dalkara, T., Couvreur, P., Capan, Y., Comparative In Vitro Studies on PBN Loaded Nanoparticles Prepared by Biodegradable Chitosan, PLGA Polymers and Their PEGylated Block Copolymers. J. Drug Del. Sci. Tech., 24(2):148-52, 2014.

• Yerlikaya, F., Ozgen, A., Vural, I., Guven, O., Karaagaoglu, E., Khan, M. A., Capan. Y., Development and Evaluation of Paclitaxel Nanoparticles Using a Quality-by-Design Approach. J. Pharm Sci, 102, 3748-3761, 2013.

• Olmez, S. S., Vural, I., Sahin, S., Ertugrul, A., Capan, Y., Formulation and evaluation

of clozapine orally disintegrating tablets prepared by direct compression. Pharmazie, 68 (2), 110-116, 2013.

• Uraz, A., Gultekin, S. E., Senguven, B., Karaduman, B., Sofuoglu, I. P., Pehlivan, S.,

Capan,Y. Eren, K. (2013). Histologic and histomorphometric assessment of eggshell-derived bone graft substitutes on bone healing in rats. Journal of Clinical and Experimental Dentistry, 5(1), e23–e29.

• Yemişci, M., Gürsoy-Özdemir, Y., Caban, S., Bodur, E., Çapan, Y., Dalkara, T.,

Transport of a caspase inhibitor across the blood-brain barrier by chitosan nanoparticles. Methods in Enzymology, 508, 253-269, 2012.

• Sipahigil, O. , Alarçin, E., Türkoǧlu, M., Dortunç, B., Karagöz, H., Ülkür, E., Vural,

I., Çapan, Y., Characterization, cell proliferation and cytotoxicity evaluation of vascular endothelial growth factor loaded poly (lactic-co-glycolic acid) microspheres. Nobel Medicus, 8, 77-82, 2012.

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• Bozdag-Pehlivan, S., Subaşi, B., Vural, I., Ünlü, N., Çapan, Y., Evaluation of drug-

excipient interaction in the formulation of celecoxib tablets Acta Poloniae Pharmaceutica - Drug Research, 2011, 68 (3), pp. 423-433, 2011.

• Cirpanli, Y., Capan, Y., Yerlikaya, F., Ozturk, K., Erdogar, N., Launay., M, Gegu, C,

Calis, S, Comparative evaluation of in vitro parameters of tamoxifen citrate loaded poly(lactide-co-glycolide), poly(β-caprolactone) and chitosan nanoparticles, Pharmazie, 65 (12), pp. 867-870, 2010.

• Ozturk, K., Caban, S., Kozlu, S., Kadayifci, E., Yerlikaya, F., Capan, Y. The

influence of technological parameters on the physicochemical properties of blank PLGA nanoparticles. Pharmazie, 65(9):665-9, 2010.

• Yerlikaya F., Aktas Y., Capan Y. LC-UV Determination of Melatonin from Chitosan Nanoparticles, Chromatographia, 9-10 (71) 967-970 , 2010.

• Karatas, H., Aktas, Y., Gursoy-Ozdemir, Y., Bodur, E., Yemisci, M., Caban, S., Vural, A., Pinarbasili, O., Capan, Y., Fernandez-Megia, E., Novoa Carballal, R., Riguera, R., Andrieux, K., Couvreur, P., Dalkara, T., A nano-medicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection, J. Neuroscience 29 (44):13761-9, 2009.

• Aktaş, B. Giray, Y. Çapan, D. Menemenlioğlu, M. Hayran, G. İkinci, İ. Vural,

Microbiological and clinical comparison of chlorhexidine buccoadhesive tablet and chlorhexidine mouthrinse, J. Drug Del. Sci. Tech., 19 (5) 353-357, 2009.

• Pinarbasli, O., Aktas, Y., Dalkara, T., Andrieux, K., Alonso, M.J., Fernandez-Megia,

E., R. Novoa-Carballal, R., Riguera, R., Couvreur, P., Capan, Y. Preparation and Evaluation of PBN-Encapsulated Chitosan and PEGylated Chitosan Nanoparticles, Pharmazie, 64(7):436-9, 2009.

• Cetin, M., Youn, Y.S., Capan, Y., Lee K.C., Preparation and characterization of

salmon-calcitonin biotin conjugates AAPS Pharm.Sci.Tech., 9 (4) pp1191-1197, 2008.

• Cetin, M., Vural, I., Capan, Y., Hincal, A.A. Preparation and characterization of

BSA loaded alginate microspheres FABAD Journal of Pharmaceutical Sciences, 32 (3) pp103-107, 2007.

• Cetin, M., Aktas, Y., Vural, I., Capan, Y., Preparation and In Vitro Evaluation of

bFGF-Loaded Chitosan Nanoparticles; Drug Delivery; 14, 1–5, 2007 .

• Na D.H., Faraj J., Capan Y., Leung K.P., DeLuca P.P. Stability of antimicrobial decapeptide (KSL) and its analogues for delivery in the oral cavity. Pharm Res 24, 1544-50, 2007.

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• Faraj, J.A., Dorati, R., Schoubben, A., Worthen, D., Selmin, F., Capan, Y., Leung, K., DeLuca P.P., The Development of a Peptide Containing Chewing Gum as a Sustained ReleaseAntiplaque Antimicrobial Delivery System. AAPS PharmSci.Tech. 8 (1), 26, 2007.

• Yemisci, M., Vural, İ., Bozdağ, S., Çetin, M., Söylemezoğlu, F., Çapan, Y., Dalkara,

T., Treatment of Malignant Glioma with Mitoxantrone-Loaded PLGA Microspheres, Neurosurgery. 59 ,1296, 2006.

• Aktas, Y., Yemisci, M., Andrieux, K., Gursoy, R.N., Alonso, M.J., Fernandez-Megia

E., Novoa-Carballal R., Quinoa E., Riguera R., Sargon M.F., Celik H.H., Demir A.S., Hincal A.A., Dalkara T., Capan Y., Couvreur P. Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26. Bioconjug. Chem. 16,1503, 2005.

• D. H.Na, J. Faraj, Y.Capan, K.P. Leung, P.P. DeLuca Chewing gum of ntimicrobial decapeptide (KSL) as a sustained antiplaque agent. Preformulation study J Control Release 107 ,122, 2005.

• M. Cetin, Y. Capan, İ. Vural, L.A. Dogan, D. Guc, A.A. Hincal, P. Wehrlé, T.

Dalkara , P.P. DeLuca, Preparation and Characterization of bFGF and BSA Loaded Microspheres, J.Drug Del. Sci. Tech.15,371, 2005.

• A.C. Kilic, Y. Capan, I. Vural, R. N. Gursoy, T. Dalkara, A. Cuine, A. Hincal,

Preparation and characterization of PLGA nanospheres for the targeted delivery of NR2B-spesific antisense oligonucleotides to the NMDA receptors in the brain J Microencapsul. 22,633, 2005.

• Y.Aktas, K.Andrieux, M.J.Alonso, P.Calvo, R.N.Gursoy, P.Couvreur, Y.Capan Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor Int J Pharm. 298,378, 2005.

• S. Bozdağ, Y. Çapan, İ.Vural, T. Dalkara, A.L. Dogan, D. Guc, A. A. Hıncal, P.P.DeLuca, Formulation and In Vitro Cytotoxicity of Mitoxantron- Loaded Biodegradable Microspheres on Rat Glioma Cells J. Drug Del. Sci. Tech., 15, 201, 2005.

• S. Bozdağ, Y. Çapan, İ. Vural. A.A.Hıncal Method Validation in Determination of

Mitoxantrone by HPLC Acta Pharmaceutica Turcica.,46:43, 2004.

• M.Cetin,Y.Capan Brain Drug targeting J.Fac.Pharm. Ankara,33,287, 2004.

• S. Bozdağ, Y. Çapan, İ.Vural, T. Dalkara, A.L. Dogan, D. Guc, A. A. Hıncal, In vitro Cytotoxıcıty of Mitoxantron-Incorporated Albumin Microspheres on Acute Promyelocytic Leukemia Cells Journal of Microencapsulation, 21,751, 2004

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• R. Elqidra, N. Ünlü, Y. Çapan, G. Şahin, T. Dalkara, A. A. Hıncal Effect of polymorphism on in vitro- in vivo properties of carbamazepine conventional tablets. J. Drug Del. Sci. Tech., 14,147, 2004.

• Y. Çapan, G. Jiang, S. Giovagnoli, K. Na, P. P. DeLuca Preparation and

characterization of poly(D,L- lactide-co-glycolide) microspheres for controlled release of human growth hormone AAPS PhamSciTech, 4, 236, 2003.

• S. Bozdag, Y. Capan, I. Vural, A.A. Hincal, P.P DeLuca Mitoxantrone loaded

poly(DL-lactide-co-glycolide) microspheres for treatment of brain tumors I. formulation and release characteristics Technology and Health Care, 10 (3-4) pp353-355, 2002.

• G. İkinci, Y. Çapan, S. Şenel, E. Alaaddinoğlu, T. Dalkara, A. A. Hıncal In vitro/in

vivo studies on buccal bioadhesive tablet formulation of carbamazepine Pharmazie, 55,762, 2000.

• H.Selek, Y.Çapan, H.S.Kaş Starch Microspheres: Importance, Preparation and

Applications FABAD J. Pharm. Sci., 24, 31, 1999 .

• Y.Çapan, B.H. Woo, S. Gebrekidan, S.Ahmed, P.P.DeLuca Stability of poly(L-Lysine) complexed plasmid DNA. Pharm.Dev. Tech. 4, 491, 1999.

• Y.Çapan, B.H. Woo, S. Gebrekidan, S.Ahmed, P.P.DeLuca Influence of formulation parameters on the characteristics of poly(D,L- lactide-co-glycolide) microsphere containing poly(L-lysine)complexed plasmid DNA. J Control Release 60, 279, 1999.

• Y.Çapan, B.H. Woo, S. Gebrekidan, S.Ahmed, P.P.DeLuca. Preparation and

characterization of poly (D,L-lactide-co-glycolide) microspheres for controlled release of plasmid DNA. Pharm. Res. 16, 509, 1999.

• G.İkinci, Y.Çapan, S.Şenel, T. Dalkara, A.A. Hıncal Formulation and In Vitro-In

Vivo investigation of carbamazepine controlled release matrix tablets Pharmazie, 54, 139, 1999.

• Y. Yazıksız-İşcan, Y, Çapan, S. Şenel, M.F. Şahin, S. Kes, D. Duchêne, A. Atilla

Hıncal. Formulation and In vitro In vivo Evaluation of Buccal Bioadhesive Captopril Tablets STP Pharma, 8, 357, 1998.

• S. Şenel, Y. Çapan, M.F. Sargon, C.B. Giray, A.A. Hıncal Histological and

Bioadhesion Studies on Buccal Bioadhesive Tablets Incorporated with a Penetration Enhancer, Sodium Glycodeoxycholate. Int. J. Pharm., 170, 239, 1998.

S. Şenel, D. Duchêne, A.A. Hıncal, Y. Çapan, G. Ponchel In Vitro Studies on Enhancing Effect of Sodium Glycocholate on Transbuccal Permeation of Morphine Hydrochloride. J Control Release, 51, 107, 1998 .

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• S. Şenel, Y. Çapan, M.F. Sargon, G. İkinci, D. Şolpan , O. Güven, H.E. Bodde, A.A.Hıncal Enhancement of Transbuccal Permeation of Morphine Sulfate by Sodium Glycodeoxycholate In Vitro. J Control Release, 45, 153, 1997.

• B. Taylan, Y. Çapan, O. Güven, S. Kas, A. A. Hıncal Design and Evaluation of

Sustained-Release and Buccoadhesive Propranolol Hydrochloride Tablets. J Control Release, 38, 11, 1996.

• F.S. Farshi, Y. Çapan, S. Kes, A.A. Hıncal Formulation and Comparative

Bioavailability of Conventional and Sustained-Release Furosemide Tablets. S.T.P. Pharma Sciences, 5, 361, 1995.

• F.S. Farshi, Y. Çapan, A.A. Hıncal Topographical Dissolution Characterization for

Sustained-Release Furosemide Tablets. Acta Pharmaceutica Turcica., 36, 118, 1994.

• Ş. Anlar, Y. Çapan, O. Güven, A. Göğüş, T. Dalkara, A. A. Hıncal Formulation and

In vitro- In vivo Evaluation of Buccoadhesive Morphine Sulphate Tablets. Pharm. Res., 11, 231, 1994.

• Ş. Anlar, Y. Çapan, A. A. Hıncal Physico-Chemical and Bioadhesive Properties of

Polyacrylic Acid Polymers. Pharmazie, 48, 285, 1993 .

• Y. Çapan, N. Çapan, H. S. Kaş, Ş. Atikcan, Y. Başer, A. A. Hıncal Formulation and Efficiency of Sustained Release Theophylline Tablets S.T.P. Pharma Sciences, 2, 169, 1992.

• S. Şenel, Y. Çapan, A. A. Hıncal Factors Affecting the Formulation of Sustained

Release Potassium Chloride Tablets Pharmazie, 46, 792, 1991.

• S. Şenel, Y. Çapan, T. Dalkara, N. İnanç, A. A. Hıncal Formulation, Bioavailability and Pharmacokinetics of Sustained Release Potassium Chloride Tablets. Pharm. Res., 8, 1313, 1991.

• K. Çiftçi, Y. Çapan, A. A. Hıncal Evaluation of Sustained Release Lithium Carbonate

Tablets from Urine S.T.P. Pharma Sciences, 1, 272, 1991.

• Y. Çapan, K. Çiftçi, A.A. Hıncal Influence of Filler Excipients on the Release Rate of Sustained Release Lithium Carbonate Tablets. Eur. J. Pharm. Biopharm., 37, 14, 1991.

• Y. Çapan, S. Kaş, L. Öner, F. Bulut-Öner, A. A. Hıncal Sustained Release Isoniasid

Tablets II. In Vivo Evaluation S.T.P. Pharma Sciences, 6, 460, 1990.

• K. Çiftçi, Y. Çapan, O. Öztürk, A. A. Hıncal Formulation and In Vitro- In Vivo Evaluation of Sustained Release Lithium Carbonate Tablets. Pharm. Res. , 7, 359, 1990.

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• F. Bulut-Öner, Y. Çapan, S. Kaş, L. Öner, A. A. Hıncal Sustained Release Isoniasid Tablets. I. Formulation and In Vitro Evaluation Farmaco., 44 ,739, 1989.

• Y. Çapan, S. Şenel, S. Çalış, S. Takka, A. A. Hıncal Formulation and In Vitro- In

Vivo Evaluations on Sustained Release Acetylsalicylic Acid Tablets. Pharm. Ind., 51, 443, 1989.

• Y. Çapan Influence of Technological Factors on Formulation of Sustained Release

Tablets. Drug Dev. Ind. Pharm., 15, 927, 1989.

• Y. Çapan Les Formes Pharmaceutiques Orales Solides à Libération Programée. Sci. Techn. Pharm., 13, 43, 1984.

• Y. Çapan Formulation de Comprimés de Nitrofurantoin à Libération Modifiée

Obtenus par Compression Directe Labo-Pharma-Probl. Tech., 31, 837, 1983.

• N. Ünlü, Y. Çapan, N. Yuluğ Formulation Studies of the Wetting Solutions for Hard Contact Lenses Microbiyol. Bull., 15, 179, 1981.

- Journal Articles (National Scientific Journals)

• Caban S, Aytekin E, Sahin A, Capan Y., Nanosystems for drug delivery. OA Drug

Design & Delivery, Jan 18;2(1):2, 2014.

• Izat, N., Yerlikaya, F., Capan. Y., A Glance on the History of Pharmaceutical Quality by Design. OA Drug Delivery and Design, Jan 18;2(1):1, 2014.

• Doğan S.S., Toktaş S., Çapan Y. ‘Drug transport across the blood-brain barrier: Trojan Technologies’ Hacettepe University Journal of the Faculty of Pharmacy, 2014-1 (in Press)

• Doğan S.S., Toktaş S., Çapan Y. ‘Brain Drug Targeting Strategies’ Hacettepe University Journal of the Faculty of Pharmacy, 2014-1 (in Press)

• Aygül, G., Yerlikaya, F., Caban, S., Vural, I., Capan, Y., Formulation and In Vitro Evaluation of Paclitaxel Loaded Nanoparticles. Hacettepe University Journal of the Faculty of Pharmacy, 33 (1):25-40, 2013.

• Ölmez, S.S., Vural, I., Şahin, S., Ertugrul, A., Çapan, Y. Orally disintegrating tablets

ii: In vitro and in vivo evaluations Hacettepe University Journal of the Faculty of Pharmacy, 31 (1), pp. 59-70, 2011.

• Ölmez, S.S., Vural, I., Şahin, S., Ertugrul, A., Çapan, Y. Orally disintegrating tablets i: Preparation technologies Hacettepe University Journal of the Faculty of Pharmacy, 30 (2), pp. 205-230, 2010.

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• Çirpanli, Y., Robineau, C., Çapan, Y., Çaliş, S. Etodolac loaded poly (lactide-co-glycolide) nanoparticles: Formulation and in vitro characterization Hacettepe University Journal of the Faculty of Pharmacy, 29 (2), pp. 105-114, 2009.

• Damadoğlu, E., Işık, R., Karakaya, G,. Çapan, Y., Kalyoncu A.F. ‘Desensitization to allopurinol in a patient with fixed drug eruption’ Asthma Allergy Immunol,7:194-197 (2009)

• Çetin, M., Vural, I., Çapan, Y., Hincal, A.A. Preparation and characterization of BSA-loaded alginate microspheres Journal of Pharmaceutical Sciences, 32 (3), pp. 103-107, 2007.

• Çetin, M., Çapan, Y. Brain drug targeting Ankara Universitesi Eczacilik Fakultesi Dergisi, 33 (4), pp. 287-305, 2004.

• Bozdag, S., Çapan, Y., Vural, I., Hincal, A.A. Method Validation in Determination of Mitoxantrone by HPLC Acta Pharmaceutica Turcica, 46 (1), pp. 43-47, 2004.

• M.Çetin , Y. Çapan bFGF ( Basic Fibroblast Growth Factor ) and a novel approach to its formulations H.U. J. Fac. Pharm., 24, 107, 2004.

• S. Bozdağ, İ. Vural, Y. Çapan, T. Dalkara Application of Drug Carrier Systems for Brain Tumor Therapy FABAD J. Pharm. Sci., 27, 89, 2002.

• R. Elqidra, N. Ünlü, Y.Çapan, A.A. Hıncal Effect of Polymorphism on Carbamazepine Tablet Characteristics H.U. J. Fac. Pharm., 21, 83,2001.

• İ. Yenice, S. Çalış, Y. Çapan Quality Control of Conventional and Controlled-Release Carbamazepine Tablets Available in Turkish Market H.U.J. Fac. Pharm.,20, 45, 2000.

• Y. Yazıksız, Y. Çapan, A.A.Hıncal Buccal Adhesive Drug Delivery Systems FABAD

J. Pharm. Sci., 22, 65 ,1997.

• Y.Çapan Controlled-Release Oral Solid Dosage Forms, General Principles Posyon, 5, 117, 1996.

• Y. Çapan Recent Pharmacopeial Controls Used for the Evaluation of Solid Dosage Forms – II POSYON, 5, 71, 1996.

• F.S. Farshi, Y. Çapan, A.A. Hıncal, Bioavailability File: Furosemide FABAD J. Pharm. Sci., 21, 87, 1996.

• Y. Çapan Recent Pharmacopeial Controls Used for the Evaluation of Solid Dosage Forms - I. POSYON, 5, 36, 1996.

• Y. Çapan Novel Approaches in Pharmaceutical Dosage Forms Rapor, 8, 4, 1995

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• Y. Çapan Quality Assurance and ISO 9000 in Pharmaceutical Industry. POSYON, 4, 44, 1995.

• Y.Çapan ISO 9000 Standards and GMP POSYON, 3, 12, 1994.

• Y. Çapan Properties and Evaluation of Sustained Release Tablets. FABAD J. Pharm. Sci., 18, 27, 1993.

• Ş. Anlar, Y. Çapan, A. A. Hıncal Bioadhesive Controlled Release Systems II. Experimental Methods for Evaluation of Bioadhesive Bond Strength of Polymers with Mucus. FABAD J. Pharm. Sci., 17, 277, 1992.

• Ş. Anlar, Y. Çapan, A. A. Hıncal Bioadhesive Controlled Release Systems I Fundamentals of Bioadhesion. FABAD J. Pharm. Sci., 17, 203, 1992.

• S.Şenel, Y.Çapan, A.A.Hıncal Applications of Thermal Analysis in Pharmaceutics. FABAD J. Pharm. Sci., 17, 45, 1992.

• Y. Çapan, A. A. Hıncal The Physics of Tablet Compression II. The Strength of Tablets. FABAD J. Pharm. Sci., 11, 82, 1986.

• Y. Çapan, A. A. Hıncal The Physics of Tablet Compression I. FABAD J. Pharm. Sci. 9, 93, 1984.

• T. Eldem, Y. Çapan Formulation Studies on Sustained Release Nitrofurantoin Tablets. Bull. Hacettepe University Faculty of Pharmacy 4, 9, 1984.

• Y. Çapan Le Choix des Excipients en Compression Directe à l'Aide des Energies de Compression FABAD J. Pharm. Sci., 9, 108, 1984.

• N. Ünlü, Y. Çapan, N. Yuluğ Formulation Studies of the Wetting Solutions for Hard Contact Lenses II. FABAD J. Pharm. Sci., 7, 125, 1982

- Book Chapters

• Yemişci, M., Capan, Y., Nanotaşıyıcıların Beyne Hedeflendirilmesi (Nanoparticles for Brain Drug Delivery), A.Z. Gürsoy (Ed) Farmasötik Nanotaşıyıcılar, Kontrollü Salım Sistemleri Derneği, İstanbul, 2014.

• S. Şenel, Y. Çapan and A. A. Hıncal Factors Affecting the Formulation of Sustained Release Potassium Chloride Tablets In : PHARMACEUTICAL TECHNOLOGY Controlled Drug Release Vol. 2 J. I. Wells and Rubinstein (Eds.) pp. 34-43, Ellis Harwood, New York, 1991

• Y. Çapan, Pharmaceutical Factors Affecting Bioavailability and Bioequivalance In: Bioavailability and Bioequivalance L. Öner, M. Şumnu, A.A.Hıncal (Eds.) Şafak Matbaası, Ankara, 1995.

15

• S. Şenel, Y. Çapan, M.F. Sargon, D. Solpan, O. Güven, H.E. Boddé, A.A. Hıncal, Enhancing Effect of Sodium Glycodeoxycholate on Diffusion Rate of Morphine Sulfate Through Buccal Epithelium In: P. Couvreur, D.D. Duch(ne, I. Kalles, (Eds), pp. 441- 445, MINUTES, Formulation of Poorly-Available Drugs for Oral Administration, European Symposium, Editions de Santé Publishers, Paris, 1996.

• Y. Çapan Kontrollü Salım Sistemlerinin Salım Mekanizmaları ve Kullanılış

Yolları (Release Mechanisms of Controlled Release Systems and Administrations Routes) In: Kontrollü Salım Sistemleri (Controlled Release Systems) Gürsoy A.Z. (Ed) pp.41-64, Elma Bilgisayar Basım ve Ambalaj San. Tic. Ltd. Şti, İstanbul, 2002.

• Y. Çapan Mukozaya Yapışan Sistemler (Mucoadhesive Systems) In: Kontrollü Salım Sistemleri (Controlled Release Systems) Gürsoy A.Z. (Ed) pp.177-196, Elma Bilgisayar Basım ve Ambalaj San. Tic. Ltd. Şti, İstanbul, 2002.

• Y. Çapan Çözünürlük ve çözünme hızına etki eden faktörler (Solubility and

factors effecting solubility rate) In: Farmasötik Teknoloji (Pharmaceutical Technology) Gürsoy A.Z. (Ed.) pp. 85-96, Piksel Bilişim Matbaacılık Reklamcılık ve Filmcilik Hizmetleri Ltd. Şti., İstanbul, 2004.

• Y. Çapan Biyoyararlanım (Bioavailability) In: Farmasötik Teknoloji

(Pharmaceutical Technology) Gürsoy A.Z. (Ed.) pp.159-168, Piksel Bilişim Matbaacılık Reklamcılık ve Filmcilik Hizmetleri Ltd. Şti., İstanbul, 2004.

• O. Pinarbasli, Y. Aktas, Y. Capan Development and Validation of an Analytical

Method for The Determination of PBN from Chitosan Nanoparticles In: Advances in Chitin Science S.Senel, K.M. Varum, M.M. Sumnu, A.A. Hincal (Eds), pp: 370-375, . Alp Ofset, Ankara, 2007.

• S. Caban, Y.Çapan, P. Couvreur, and T. Dalkara Preparation and Characterization of Biocompatible Chitosan Nanoparticles for Targeted Brain Delivery of Peptides In: Methods and Protocols, Methods in Molecular Biology, Vol. 846 / Ch-27 Stephen D. Skaper (ed.) pp: 321-331, LLC 2012.

• Müge Yemişci, Yasemin Gürsoy-Özdemir, Seçil Caban, Ebru Bodur, Yılmaz Çapan,

and Turgay Dalkara Transport of a Caspase Inhibitor Across the Blood–Brain Barrier by Chitosan Nanoparticles. In: Methods in Enzymology, Vol. 508 Nejat Düzgüneş (ed.) pp. 253-269, Burlington: Academic Press, 2012.

Invited Presentations

• Y. Çapan,

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Preparation and Characterization of Poly (D,L-lactide-co-glycolide) Microspheres For Controlled Release of Poly (L-Lysine) Complexed Plasmid DNA., 8th Biomedical Science and Technology Symposium, September 5-8, 2001 Ankara.

• Y. Çapan,

Overview of Bioavailability/Bioequivalance Studies in Turkey, ISHDRLP 2 (International Symposium on Harmonizaiton and Drug Registration and Licensing Procedures), 9-11, October 2001, İstanbul.

• Y. Çapan, Dissolution rate, Influence of Technological Parameters on Dissolution Rate, and Evaluation of Dissolution Rate Data, 7th International Symposium on Pharmaceutical Sciences, June 23-27 2003, Ankara.

• Y. Çapan, Mitoxantrone Loaded Albumin Microspheres and Cytotoxicity Against Acute Promyelocytıc Leukemia Cells, 7th US-Japan Symposium on Drug Delivery systems, December 14-19, 2003, Hawaai.

• Y. Çapan, Issues and challenges in the area of BE and dissolution International Regulatory Workshop on Bioequivalence and Dissolution, November 29-30, 2004, İstanbul, TURKEY.

• Y.Çapan,

Nanoparticle technology & its Pharmaceutical Applications Advances in Technology & Business Potential of New Drug Delivery Systems February 18-19, 2005, Mumbai-India

• Y.Capan,

Nanoparticle technology & its Pharmaceutical Applications FIP Meeting,Cairo,2005

• Y.Capan, An overview of dissolution and bioequivalence Hands-On-Dissolution Workshop October 10-11,2005,Istanbul-Turkey

• Y.Capan,

BE practice and issues in Turkey Biointernational 2005 24-26 October 2005, London

• Y.Capan, Recent Advances in Brain Drug Delivery International Symposium on Drug Research and Development From Chemistry to Medicine 17-20 May 2007, Antalya -Turkey

• Y.Capan, Recent Advances in Brain Drug Delivery 16th International Symposium on Microencapsulation 9–12 September 2007, Lexington, Kentucky-USA

• Y. Capan,

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Technological Factors Influencing BA / BE, FATUM Symposium on Bioavailability / Bioequivalance and Regulatory Issues, 17-18 March 2008, Maslak / Istanbul, Turkey.

• Y. Capan, Bioavailability and Bioequivalance 34. National Haematology Congress, October 8-11, 2008, İzmir-Turkey.

• Y. Capan, Perspectives in drug release from micro- and nanoparticulate drug delivery systems, 14th Internetional Pharmaceutical Technology Symposium, September 6-10, 2008, Antalya -Turkey.

• Y. Capan, Blood Brain Barrier Delivery with Molecular Trojan Horses, 14th Internetional Pharmaceutical Technology Symposium, September 6-10, 2008, Antalya - Turkey

• Y. Capan,

Bioavailability & Bioequivalance BioInternational 2008 October, 22-24, London.

• Y. Capan, Evaluation of the products with the same formula on the point of pharmaceutical technolgy Turkish Society of Hematology Updating on Hematological Oncology Meeting 6-9 May 2010, Marmaris, Muğla, Turkey

• Y. Capan, Brain Drug Targeting IMPPS-3, Third International Meeting On Pharmacy & Pharmaceutical Sciences June 9-12 2010,

• Y. Capan, Brain Drug Targeting 16th International Biomedical Science and Technology Symposium, September 28—October 2, 2010 Istanbul Turkey

• Y. Capan Brain Drug Targetting 15th Internetional Pharmaceutical Technology Symposium, 13-15 September 2010, Antalya, Turkey

• Y. Capan, The importance of particle size analysis: Its role in pharmaceutical development United States Pharmacopeia and Ekin Kimya 4th Science & Standards Symposium October 15, 2010 - Istanbul, Turkey

• Y. Capan, Nanoparticular Drug Delivery Systems & Pharmaceutical Applications IAEA Regional Training Course on ˝Radiation Synthesis and Characterization of Nanostructures 8 -12 November 2010, Ankara, Turkey

• Y. Capan,

Nanoscale drug delivery systems and the blood-brain barrier. 17th International Pharmaceutical Technology Symposium. Antalya, Turkey, 8-10 September 2014.

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• Y. Capan,

Brain drug delivery. International Conference on Advances in the Area of Bioequivalance, Pharmaceutical Technology Symposium. Budapest, Hungary, 14 November 2015.

Poster Presentations

• Y. Çapan, A. Delacourte, J. C. Guyot, M. Traisnel, Elaboration de Critéres d

'Optimisation dans la Fabrication de Comprimés VII. Bilim Kongresi (TUBİTAK) 1980, Ankara.

• T. Eldem, Y. Çapan, Formulation Studies on Sustained Release Nitrofurantoin Tablets, Proc. 3rd Int. Conf. Tech., APGI, Paris, Vol I, pp 137-144 , 1983.

• Y. Çapan, S. Şenel, S. Çalış, A.A. Hıncal Formulation and Biopharmaceutical

Evaluation of Sustained Release Tablets of Aspirin.3rd International Pharmaceutical Technology Symposium, Sept. 9-11 , 1986, Ankara.

• K. Çiftçi, Y. Çapan, O. Öztürk, A. A. Hıncal Formulation and In Vitro-In Vivo Evaluations on Sustained Release Lithium Carbonate Tablets. 4th International Pharmaceutical Technology Symposium, Sept. 12-14, 1988, Ankara.

• S. Şenel, Y. Çapan, F. Z. Muluk, A. A. Hıncal, Formulation and In Vitro Evaluation of Sustained Release Potassium Chloride Tablets. 4th International Pharmaceutical Technology Symposium, Sept. 12-14 , 1988, Ankara.

• Y. Çapan, Influence of Technological Factors on Formulation of Sustained Release Tablets, 4th International Pharmaceutical Technology Symposium, Sept. 12-14,1988, Ankara.

• S. Şenel, Y. Çapan, A. A. Hıncal, Factors Affecting the Formulation of Sustained Release Tablets 3rd Turkish Pharmacy Congress pp 106-112, May 11-13, 1989, İstanbul.

• F. Bulut-Öner, Y. Çapan, S. Kaş, L. Öner, A. A. Hıncal, Sustained Release soniasid Tablets I. Formulation and In Vitro Evaluation, Proc. 5th Int. Conf. Pharm. Tech., APGI, Paris, Vol I, pp 356-365,1989.

• Y. Çapan, S. Kaş, L. Öner, F. Bulut-Öner, A. A. Hıncal, Sustained Release Isoniasid Tablets II. In Vivo Evaluation, Proc.5th Int. Conf. Pharm. Tech., APGI, Paris, Vol I, pp 366-370, 1989.

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• Y. Çapan, K. Çiftçi, A. A. Hıncal, Influence of Filler Excipients on the Release Rate of Sustained Release Lithium Carbonate Tablets, Proc. 5th Int. Conf. Pharm. Tech., APGI, Paris, Vol IV, pp 110-117, 1989.

• K. Çiftçi, Y. Çapan, A. A. Hıncal, Relationship Between Serum Concentration and Urinary Excretion Rate of Lithium in Man Following Administratıon of a Conventional and Sustained Release Lithium Carbonate Tablet, Proc. 5th Int. Conf.Pharm. Tech., APGI, Parıs, Vol IV, pp 118-125, 1989.

• S. Şenel, Y. Çapan, A. A. Hıncal, Factors Affecting the Formulation of Sustained Release Potassium Chloride Tablets. Proc. 9th Tech. Conf. Veldhoven, Vol II, pp 71-86, 1990

• Y. Çapan, H. S. Kaş, N. Çapan, Y. Başer, A. A. Hıncal Formulation and Pharmacokinetic Evaluation of Sustained Release Theophylline Tablets. 50th Congress of F.I.P., İstanbul, 1990.

• Ş. Anlar, Y. Çapan, O. Güven, A. Göğüş, T. Dalkara, A. A. Hıncal Studies on Buccoadhesive Tablet Formulation of Morphine Sulphate. Proc. 6th Int. Conf. Pharm. Tech., APGI, Paris Vol II , pp 20-29, 1992.

• B. Taylan, Y. Çapan, A.A Hıncal Formulation and In Vıtro Evaluation of Sustained Release and Buccoadhesive Propranolol Hydrochloride Tablets. Proc. 6th. Int. Conf. Pharm. Tech., APGI, Paris, Vol II pp 30-39,1992.

• F.S. Farshi, Y. Çapan, S. Kes, A.A. Hıncal Formulation and Bioavailability of Conventional and Controlled Release Furosemide Tablets. 9th International Symposium on Microencapsulation, Ankara, 1993.

• Y. Çapan, L. Öner, A. A. Hıncal Bioequivalance Concept In: Proc.Importance of Drug Bioavailability in Pharmacology and Product Evaluation. Turkish Pharmacological Society, Ankara, pp 39-57, 1993.

• Y.Çapan Controlled Drug Delivery Systems : Tablets, 1st National Symposium on Biomedical Science & Technology Sept. 19-21, 1994, Ankara

• B.Taylan, Y. Çapan, S. Kaş, O. Güven, A. A. Hıncal In vitro- In vivo Evaluation of Sustained Release and Buccoadhesive Propranolol Hydrochloride Tablets 7th Int. Pharm. Tech. Symp., 12-14 Sept. 1994, Ankara.

• Y. Çapan, Mucosal Adhesive Preparations Second National Symposium on Biomedical Science and Technology, pp 15-17, 21-23 September 1995, METU – ANKARA

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• S. Şenel, Y. Çapan, M.F. Sargon, G. İkinci, D. Solpan, O. Güven, H.E. Boddé, A.A. Hıncal, Enhancing Effect of Sodium Glycodeoxycholate on Diffusion Rate of Morphine Sulphate Through Buccal Epithelium. European Symposium on Formulation of Poorly-Available Drugs for Oral Administration, 1996, Paris-FRANCE

• Y. Yazıksız, Y. Çapan, S. Şenel, F. Şahin, S. Kes, D. Duchêne, A.A. Hıncal Buccal Absorption of Captopril Using a Buccal Bioadhesive Tablet 8th Int. Pharm. Tech. Symp., 9-11 Sept. 1996, Ankara

• Y. Yazıksız, Y. Çapan, S. Şenel, F. Şahin, D. Duchêne, A.A. Hıncal Effect of Interpolymer Complex Formation on Bioadhesive Property of Buccal Adhesive Captopril Tablets 8th Int. Pharm. Tech. Symp., 9-11 Sept. 1996, Ankara

• S. Şenel, Y. Çapan, M.F. Sargon, C.B. Giray, A.A.Hıncal Histological and Bioadhesion Studies on Buccal Bioadhesive Tablets 8th Int. Pharm. Tech. Symp., pp. 113-114, 9-11 Sept. 1996, Ankara

• Hıncal, Y. Çapan Bioavailability of Controlled Release Dosage Forms The Third National Symposium on Biomedical Science and Technlogy, pp. 31-32 December, 11-14 1996, Uludağ - BURSA

• G. İkinci, Y.Çapan, S. Şenel, T.Dalkara, F. Şahin, A.A. Hıncal Formulation and In Vitro - In Vivo Evaluation of Controlled-Release Carbamazepine Tablets The Fourth International Symposium on Biomedical Science and Technology, pp. 61- 62, 15 - 17 September 1997, İSTANBUL

• H.Selek, H.S.Kaş, M.F.Sargon, Y.Çapan, A.A.Hıncal Preparation and Evaluation of Degradable Starch Microspheres of Terbutaline Sulfate 5th European Symposium on Controlled Drug Delivery, 1-3 April 1998, Noordwijkaan Zee, Netherlands.

• H.Selek, H.S.Kaş, M.F.Sargon, Y.Çapan, A.A.Hıncal Formulation and In Vitro Evaluation of Terbutaline Sulfate Loaded Poly (D,L- Lactide-co- glycolide) and Poly(L-lactide) Mixture Microspheres 9th Int. Pharm. Tech. Symp., pp. 73-74, 7-9 Sept. 1998, Ankara

• S. Bozdağ, S.Çalış, H.S. Kaş, Y. Çapan., M.T. Ercan, H. Ertürk, A.A. Hıncal Intraarticular Administration of Biodegradable Microspheres Containing Naproxen Sodium, AAPS Annual Meeting, November 14-19, 1998, San Fransisco, USA.

• H. Selek, H.S. Kaş, M.F., Sargon, Y. Çapan, A.A.Hıncal Formulation and In Vitro Characterization of Terbutaline Sulphate Microspheres by Natural and Synthetic Polymers AAPS Annual Meeting, Nov. 14-19, 1998, San Francisco, USA.

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• Y.Çapan, S.Ahmed, S. Gebrekidan, B.H. Woo, P.P. DeLuca Preparation and

Characterization of Poly (D,L- Lactide Co-Glycolide) Microspheres for Controlled Release of Plasmid DNA AAPS Annual Meeting, Nov. 14-19, 1998, San Francisco, USA.

• Y.Çapan, S.Kaş, D.Duchêne, A.A.Hıncal Evaluation of Bioavailability : Immediate Release vs Controlled Release 2nd International Clinical Pharmacy Conference Opportunities-Challenges April 21-22,1999, Amman, Jordan

• Y.Çapan Controlled Release Therapeutic Systems 6th National Symposium on Biomedical Science & Technology Oct. 6-8 1999, İzmir.

• Y.Çapan Controlled Release Dosage Forms: Terminology, advantages, marketplace and pharmacoeconomic evaluation 1st Symposium of Controlled Release Systems Sept. 29 1999, İstanbul, Turkey.

• İ.Yenice, S.Çalış, Y.Çapan, A.A. Hıncal Quality Control of Conventional and Controlled Release Carbamazepin Tablets 6th National Symposium on Biomedical Science & Technology Oct. 6-8 1999, İzmir.

• G. İkinci, Y. Çapan, S. Şenel, M. F. Sargon, E. Alaaddinoğlu, A. A. Hıncal Histological Studies on the Effect of Buccal Bioadhesive Tablet Formulation on Buccal Mucosa6h International Symposium on Pharmaceutical Sciences, ISOPS-6 June29, 2000 Ankara

• S. Bozdağ, Y. Çapan, İ. Vural, A.A. Hıncal, P.P. DeLuca, Mitoxantrone Loaded Poly (D,L-lactide-co-glycolide) Microspheres For Treatment of Brain Tumors I. Formulation and Release Characteristics, 8th Biomedical Science and Technology Symposium, September 5-8, 2001 Ankara.

• S. Bozdağ, Y. Çapan, İ. Vural, A.A. Hıncal, P.P. DeLuca, Validation of an HPLC Method for Quantitaive Analysis of Mitoxantrone, AAPS Annual Meeting, October 21-25, 2001 Colorado-USA

• Y. Aktaş, K.Andrieux, Y. Çapan, P. Couvreur, Encapsulation d’inhibiteurs des caspases dans des nanoparticules adressées par la transefrrine, Les Deuxième Journées de l’École Doctorale “Innovation Thérapeutique”, 23-24 Mai 2002, Paris, France.

• M. Çetin, Y. Çapan, İ.Vural, P.Wehrle, A.A. Hıncal, Preparation and Characterization of Chitosan and PLGA Particles for the treatment of Neurodegenerative Diseases, 11th International Pharmaceutical Technology Symposium, September 9-11, 2002, İstanbul, Turkey.

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• Subaşı, N. Ünlü, Y. Çapan, A.A. Hıncal, Evaluation of the Interaction Between

Celecoxib and Some Solid Dosage Form Excipients, 11th International Pharmaceutical Technology Symposium, September 9-11, 2002, İstanbul, Turkey.

• S. Bozdağ, Y. Çapan, İ. Vural, A.A. Hıncal, P.P. DeLuca, Preparation and Characterization of Mitoxantrone Loaded Chitosan Microspheres Against Malignant Gliomas, EUFEPS 2002, October 20-23, 2002, Stockholm, Sweden.

• S. Bozdağ, Y. Çapan, İ. Vural, A.A. Hıncal, P.P. DeLuca, Effect of Surfactant Concentration on Characteristics of PLGA Microspheres Loaded with Mitoxantrone, AAPS 2002, November 10-14, 2002, Toronto, Canada.

• M. Çetin, A.C. Kılıç, Y. Çapan, İ. Vural, A.A. Hıncal, Validation of a Spectrophotometric Quantification of Paracetamol, 7th International Symposium on Pharmaceutical Sciences, June 23-27 2003, Ankara.

• M. Çetin, Y. Çapan, İ. Vural, A.A. Hıncal, Determination of BSA Content in Microspheres by Using BCA Protein Assay, 7th International Symposium on Pharmaceutical Sciences, June 23-27 2003, Ankara.

• M. Çetin, A.C. Kılıç, Y. Çapan, İ. Vural, P. Wehrle, M.F. Sargon, A.A. Hıncal, Preparation and Characterization of PLGA Nanospheres for Brain Drug Targeting, 30th Annual Meeting and Exposition, July 19-23,2003, Glasgow, Scotland.

• S. Bozdağ, Y. Çapan, İ. Vural, T. Dalkara, P.P. DeLuca, A.A. Hıncal, Mitoxantrone Incorporated Biodegradable Microspheres for the Treatment of The Malignant Glioma, 30th Annual Meeting and Exposition, July 19-23,2003, Glasgow, Scotland.

• M. Çetin, Y. Çapan, İ. Vural, P. Wehrlé, M.F. Sargon, A. A. Hıncal, The Preparation and Characterization of Poly(Lactide-Co-Glycolide) Microparticles as Protein Carriers, AAPS-2003 Annual Meetings and Exposition, October 26-30 , Utah, USA.

• S. Bozdağ, Y. Çapan, İ. Vural, T. Dalkara, A.L.Dogan, D.Guc, A.A.Hıncal, P.P.DeLuca, In Vitro Cytotoxicity of Mitoxantrone Loaded Albumin Microspheres Against Rat Glioma Cells in Culture, AAPS 2003, Annual Meeting and Exposition, October 26-30, 2003, Utah-USA.

• M. Cetin, I. Vural, Y. Capan, A. A. Hincal, Effects of manufacturing parameters on the characteristics of the famotidine loaded chitosan beads and microspheres, 12th

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International Pharmaceutical Technology Symposium, September 12-15, 2004, İstanbul, Turkey.

• M. Cetin, Y. Capan, I. Vural, A. L. Dogan, D. Guc, T. Dalkara,P. Wehrlé, A. A. Hincal, P. P. DeLuca, Preparation and Characterization of Basic Fibroblast Growth Factor (bFGF)-Loaded Microparticulate Drug Delivery Systems, AAPS-2004 Annual Meetings and Exposition, November 7-11, 2004, Baltimore, MD.

• Kilic, Y. Capan, I. Vural, N. Gursoy, T. Dalkara, A. Cuine, A. Hincal, P. DeLuca Preparation and Characterization of Nanoparticles for the Targeted Delivery of Antisense Oligonucleotides to Brain, AAPS-2004 Annual Meetings and Exposition, November 7-11, 2004, Baltimore, MD.

• S. S. Duman, M. Cetin, I. Vural, Y. Çapan, T. Dalkara, A. A. Hincal, Preparation of Poysorbate-80 coated PLGA nanoparticles loaded with BFGF for Brain targeting,Pharmaceutical Sciences&Fair Exhibition,June 12-17 2005 Nice-France.

• J.Faraj, R.Dorati, Y.Capan , K. Leung, P.DeLuca Chewing Gum of an Decapeptide, KSL (W), as an Antiplaque Delivery System AAPS-2006 Annual Meetings and Exposition, October 29-November 2, 2006 San Antonio,TX

• M.Yemisci, İ.Vural, S. Pehlivan, M. Çetin, F.Söylemezoglu, Y.Capan, T.Dalkara, Inhibition of Malignant Glioma with Mitoxantrone-Loaded PLGA Microspheres, AAPS-2006 Annual Meetings and Exposition, October 29-November 2, 2006 San Antonio,TX

• M. Çetin , Y. Aktas , S.S.Olmez , İ.Vural , A.L.Dogan , Y.Capan , A.A.Hincal Preparation and Characterization of bFGF-Loaded Chitosan Nanoparticles, AAPS-2006 Annual Meetings and Exposition, October 29- November 2, 2006 San, Antonio,TX

• M. Cetin, Y. S. Youn, Y. Capan, K. C. Lee. Evaluation of intrajejunal delivery of biotinylated salmon calcitonins (sCTs) PSWC 2007 – Pharmaceutical Sciences World Congress, 22-25 April 2007, Amsterdam, The Netherlands

• O. Pinarbasli, M. Cetin, Y. Aktas, Y. Capan. Preparation and Characterization of BSA-loaded Chitosan Nanoparticles PSWC 2007 – Pharmaceutical Sciences World Congress, 22-25 April 2007, Amsterdam, The Netherlands

• O. Pinarbasli, Y. Aktas, M. Cetin, Y. Capan. Preparation of Chitosan Nanoparticles Encapsulating Bovine Serum Albumin 34th Annual Meeting & Exposition of The Controlled Release Society July 7-11, 2007, Long Beach Convention Center Long Beach, California-U.S.A.

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• M. Cetin, Y. Aktas, I. Vural, L. Dogan, M. Duman, T. Dalkara, Y. Capan The

Preparation and In Vitro Evaluation of Chitosan Nanoparticles Containing bFGF for Treatment of Neurodegenerative Diseases, 34th Annual Meeting & Exposition of The Controlled Release Society , July 7-11, 2007, Long Beach Convention Center Long Beach, California-U.S.A.

• O. Pinarbasli, Y. Aktas, Y. Capan Development and Validation of an Analytical Method for The Determination of PBN from Chitosan Nanoparticles 8th International Conference of the European Chitin Society- EUCHIS’ 07 8-11 September 2007, Antalya-TURKEY.

• Y. Capan Neurotherapeutic Nanoparticulate Drug Delivery Systems XXIInd (Groupe Thematique de Recherche sur le Vecteurs) 17-19 September 2007, Strasbourg-France.

• O. Pinarbasli, Y. Aktas, Y. Capan The Preparation and In Vitro Evaluation of Chitosan Nanoparticles Containing PBN for Treatment of Neurodegeranative Diseases, 14th Internetional Pharmaceutical Technology Symposium, September 6-10, 2008, Antalya –Turkey

• M. Çetin, I. Vural, S. Bozdag-Pehlivan,T. Dalkara,Y. Capan Preparation and Evaluation of bFGF-loaded PLGA Nanoparticles on MCF-7 Cells, 2008 AAPS Annual Meeting and Exposition, November 16-20, 2008, Atlanta, Georgia, USA.

• S. Bozdag-Pehlivan,I. Vural,M. Cetin,Y. Capan Design of Microencapsulated Alginate Microspheres for Colon Targeted Drug Delivery, 2008 AAPS Annual Meeting and Exposition, November 16-20, 2008, Atlanta, Georgia, USA.

• S. Caban, E. Kadayifci, S. Kozlu, K. Ozturk, F. Yerlikaya, E. Fernandez-Megia, R. Novoa-Carballal, E. Quiñoá, R. Riguera, Y. Aktas, T. Dalkara, Y. Capan, The Preparatıon And Characterızatıon Of Chıtosan–Based Nanopartıcles, 17th international Symposium on MICROANCAPSULATION, 29.09.2009 – 01.10.2009, Nagoya, JAPAN

• K. Ozturk, S. Caban, E. Kadayifci, S. Kozlu, F. Yerlikaya, Y. Capan, The Influence Of Technologıcal Parameters On The Characterızatıon Of Blank Plga Nanopartıcles, 17th international Symposium on MICROANCAPSULATION, 29.09.2009 – 01.10.2009, Nagoya, JAPAN

• F. Yerlikaya, M. Launay, C. Gegu, T. Leturgez, E. Bilensoy, S. Çalış, Y. Çapan, Analytical Method Development And Validation Of Tamoxifen Citrate Using Normal Phase High Performance Liquid Chromatography, 3rd BBBB-Bosphorus International Conference on Pharmaceutical Sciences, October 26-28 2009, Antalya, Turkey

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• H. Karatas, Y. Aktas, Y. Gursoy-Ozdemir, E. Bodur, M. Yemisci, O. Pinarbasli,

S. Caban, Y. Capan, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, T. Dalkara, A nano-medicine transports a peptide caspase-3 inhibitor across the blood-brain barrier (BBB) and provides neuroprotection; 2009 AAPS Annual Meeting and Exposition, November 8-12, 2009, Los Angeles, CA, USA

• K. Ozturk, F. Yerlikaya, Y. Capan, A validated reversed-phase high pressure liquid chromatography (HPLC) method for the in vitro determination of alpha-phenyl-N-tert-butyl nitrone (PBN); 2009 AAPS Annual Meeting and Exposition, November 8-12, 2009, Los Angeles, CA, USA

• H. Karatas, Y. Aktas, Y. Gursoy-Ozdemir, E. Bodur, M. Yemisci, O. Pinarbasli, S. Caban, Y. Capan, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, T.Dalkara, Brain delivery of fluorescent dyes loaded chitosan based nanoparticles; 2009 AAPS Annual Meeting and Exposition, November 8-12, 2009, Los Angeles, CA, USA

• S. Kozlu, F.Yerlikaya, Y. Capan, Development and validation of a reversed-phase high performance liquid chromatography (HPLC) method for the in vitro determination of an antisense oligonucleotide; 2009 AAPS Annual Meeting and Exposition, November 8-12, 2009, Los Angeles, CA, USA

• S. Caban, F. Yerlikaya, Y. Capan, Development and validation of an analytical high pressure liquid chromatography (HPLC) method for a caspase inhibitor peptide Z-DEVD-FMK; 2009 AAPS Annual Meeting and Exposition, November 8-12, 2009, Los Angeles, CA, USA

• K. Ozturk, S. Caban, E. Kadayifci, S. Kozlu, F. Yerlikaya, Y. Capan, The influence of technological parameters on the physicochemical properties of blank PLGA nanoparticles; 2009 AAPS Annual Meeting and Exposition, November 8-12, 2009, Los Angeles, CA, USA

• K. Ozturk, M. Yemisci, Y. Gursoy-Ozdemir, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, T. Dalkara, Y. Capan, In-vitro and in-vivo evaluation and design of nano/micro particular drug delivery systems loaded with Alfa-Fenil-N-Tert-Butil Nitron (PBN) as a free radical scavanger for the treatment of serebral ischemia, Hacettepe University, ARGEP, 2010, Ankara-Turkey

• S. Caban, M. Yemisci, Y. Gursoy-Ozdemir, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, Y. Capan, T. Dalkara, Preperation and evaluation of brain transport and efficiency of the basic fibroblast

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growth factor loaded brain targeted nanoparticles, Hacettepe University, ARGEP, 2010, Ankara-Turkey

• S. Caban, H. Karatas, M. Yemisci, Y. Gursoy-Ozdemir, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, Y. Capan, T. Dalkara, Preperation and evaluation of brain transport and efficiency of the caspase 3 enzyme inhibitor loaded brain targeted nanoparticles, Hacettepe University, ARGEP, 2010, Ankara-Turkey

• S. Kozlu, Y. Gursoy-Ozdemir, M. Yemisci, S. Lule, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, Y. Capan, T. Dalkara, Design of antisense oligonucleotide loaded, brain targeted nanoparticles against cytotoxic brain edema Hacettepe University, ARGEP, 2010, Ankara-Turkey

• K. Ozturk, Y. Capan. Preperation and characterization of PBN loaded poly(DL-lactide-co-glycolide) nano/microparticles The 37th Annual Meeting and Exposition of The Controlled Release Society July10-14 2010, Oregon Convention Center, PORTLAND, OREGON, U.S.A.

• S. Kozlu, Y. Gursoy-Ozdemir, M. Yemisci, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, T. Dalkara, Y. Capan. Development of an oligonucleotide carrier nanoparticulate system with modified chitosan polymers The 37th Annual Meeting and Exposition of The Controlled Release Society July10-14 2010, Oregon Convention Center, PORTLAND, OREGON, U.S.A.

• K. Öztürk, M. Yemişci,Y. Gürsoy-Özdemir, Y. Çapan, T. Dalkara. In Vitro Evaluation of PBN Loaded PLGA Nano/Microparticles 2010 AAPS Annual Meeting and Exposition, November 14-18, 2010, New Orleans, LA, USA

• S. Caban, M. Yemisci, Y. Gursoy-Ozdemir, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, K. Andrieux, P. Couvreur, Y. Capan, T. Dalkara Concommitant Transport of a CAspase Inhibitor Peptide and a Neurotropin Through The Blood Brain Barrier (BBB) via Nanoparticles Enhanced Neuroprotection 2010 AAPS Annual Meeting and Exposition, November 14-18, 2010, New Orleans, LA, USA

• F. Yerlikaya, G. Aygül, C. Ulutaş, Y. Capan, The Influence of Technological Parameters on the Physicochemical Properties of Blank PLGA Nanoparticles 2010 AAPS Annual Meeting and Exposition, November 14-18, 2010, New Orleans, LA, USA

• Dinc, B., Coskun, I., Capan, Y. Influence of the Shape and Particle Size of Nanoparticles on Biological Membrane Interactions, 2012 AAPS Annual Meeting and Exposition, October 14-18, 2012, Chicago, IL, USA

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• Caban, S., Ozturk, K., Kozlu, S., Yemisci, M. Fernandez-Megia, E., Novoa-Carballal, R., Riguera, R., Capan, Y. Investigation of Neuroprotection using PBN and Antisense Oligonucleotide Loaded Biodegradable Nanocarriers, 2012 AAPS Annual Meeting and Exposition, October 14-18, 2012, Chicago, IL, USA

• Yuce, M., Capan, Y. Evaluating the Polyethylene Glycol 4000 Stabilizing

Mechanism on Candesartan Cilexetil in Tablet Formulations, 2012 AAPS Annual Meeting and Exposition, October 14-18, 2012, Chicago, IL, USA

• Caban, S., Fernandez-Megia, E., Novoa-Carballal, R., Riguera, R., Capan, Y. Preparation and characterization of chitosan and PLGA nanoparticles with different particle size and surface charge to evaluate the cellular membrane interactions, November 10-14, 2013, San Antonio, USA.

• Yuce, M., Capan, Y. Estimating the Dissolution of Poorly Water Soluble Candesartan

Cilexetil Drug Substance from Tablet Formulations with Full Factorial Design Approach, November 10-14, 2013, San Antonio, USA.

• Yuce, M., Eroğlu, H., Capan, Y. Development and validation of HPLC analytical method used for dissolution testing of candesartan cilexetil tablets. American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, San Diego/CA, USA, November 2014.

• Caban, S., Fernandez-Megia, E., Novoa-Carballal, R., Riguera, R., Capan, Y. Preparation and Charactherization of Ziconotide Loaded Biodegradable Nanocarriers. American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, San Diego/CA, USA, November 2014.

• Caban, S., Guney, S., Erdogdu, C., Sahin, A., Ozalp, M., Aktas, A., Capan, Y. Inhibition of Microbial Leakage at Implant-Abutment Interface with Chitosan Gels. American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, San Diego/CA, USA, November 2014.

• Babat, D., Caban, S., Sahin, A., Yerlikaya, F., Vural, I., Capan, Y. Formulation and In Vitro Evaluation of Nanoparticles Containing Docetaxel. American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, San Diego/CA, USA, November 2014.

• Sahin, A.,Toktas, S., Aktas, Y., Capan, Y. 'Preparation and in vitro Evaluation of Ziconotide Loaded PLGA and Chitosan Nanoparticles 'October 2-4, 2015, Barcelona BioMed Conference "Blood Brain Barrier", Barcelona, Spain.

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• Sahin, A.,Toktas, S., Kyzy, G.A., Yerlikaya, F., Aktas, Y., Capan, Y. 'Determination of Critical Parameters of Paclitaxel and Flurbiprofe n Co-Loaded PLGA Nanoparticles Prepared by Nanoprecipitation'October25-29, 2015, Orlando, USA.

• Sahin, A.,Toktas, S., Aktas, Y., Capan, Y. 'Partide Size Optimization of Ibuprofen Loaded PLGA Nanoparticles Using Box—Behnken Design' October 25-29, 2015, Orlando, USA.

• Caban-Toktas, S., Lule, S., Sahin, A., Kara, A., Bozdag Pehlivan, S., Vural, L, Karli Oguz, K., Mut Askun, M, Capan, Y. 'In Vitro and In Vivo Evaluation of Paclitaxel and R-Flurbiprofen Loaded Chitosan Coated PLGA Nanoparticles'October 25-29, 2015, Orlando, USA.

• Kyzy, G.A., Toktas, S., Sahin, A., Capan, Y. 'Effects of Combined Suıfactants in the Formulation of Docetaxel-Loaded PLGA Nanoparticles' October 25-29, 2015, Orlando, USA.

• Sahin, A., Esendagli, G., Yerlikaya, F., Kozlu, S., Yoyen Ermis, D., Horzum, U., Aktas, Y., Khan, M, Couvreur, P., Capan, Y. “Intracellular delivery and intraperıtoneal retention of different sized PLGA nanoparticles prepared by nanoprecipitation method” 18th International Pharmaceutical Technology Symposium-IPTS 2016, September 18-21 2016, Antalya, Turkey.

• Tonbul, H., Sahin, A., Kaynak, M.S., Capan, Y. “Development and in vitro evaluation of transferrin targeted PLGA nanoparticle” 18th International Pharmaceutical Technology Symposium-IPTS 2016, September 18-21 2016, Antalya, Turkey.

• Kozlu, S., Sahin, A., Sahan, S., Yerlikaya, F., Capan, Y. “Co-Encapsulation Studies of Doxorubicin and Celecoxib in PLGA Nanoparticles” 18th International Pharmaceutical Technology Symposium-IPTS 2016, September 18-21 2016, Antalya, Turkey.

• Akbas, S., Ultav, G., Tonbul, H., Sahin, A., Capan, Y. ‘’ Characterization Of Bevacizumab By Dynamic Light Scattering Technique’’ 2nd International Gazi Pharma Symposium Series (GPSS-2017), October 11-13, 2017, Ankara, Turkey

• Ultav, G., Akbas, S., Tonbul, H., Sahin, A., Capan, Y. ‘’ Development And In Vitro Evaluation Of pH Triggered Hollow Silica Nanoparticles As A Drug Delivery System’’ 2nd International Gazi Pharma Symposium Series (GPSS-2017), October 11-13, 2017, Ankara, Turkey

• Tonbul, H., Akbas, S., Ultav, G., Sahin, A., M.S., Kaynak, Aktas, Y., Capan, Y. ‘’ Syntesis And Characterization Of Silica Nanoparticles: Obtaining Nanoparticles

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Smaller Than 100 nm’’ 2nd International Gazi Pharma Symposium Series (GPSS-2017), October 11-13, 2017, Ankara, Turkey

• Akbas, S., Ultav, G., Tonbul, H., Sahin, A., Capan, Y. ‘’ A Comperison Of PLGA Nanoparticle Preparation Methods For Bevacizumab Encapsulation’’ 12th International Symposium on Pharmaceutical Sciences (ISOPS), , 26-29 June 2018, Ankara, Turkey

• Tonbul, H., Akbas, S., Ultav, G., Sahin, A., Aktas, Y., Capan, Y. ‘’ Developmet And Evaluation Of Silica Nanoparticles Using A Quality By Design Approach’’ The European Federation for Pharmaceutical Sciences (EUFEPS), 24-26 May 2018, Athens, Greece

• Tonbul, H., Akbas, S., Ultav, G., Sahin, A., Aktas, Y., Capan, Y. ‘’In Vitro Evaluation Of Paclitaxel Loaded Mesoporous Silica Nanoparticles’’ The European Federation for Pharmaceutical Sciences (EUFEPS), 24-26 May 2018, Athens, Greece

Scientific Awards

• Golden Mortar R&D Award (ILKO Pharmaceuticals) 2016

• Turkish Public Health Institution, National Cancer Week, Encouragement Award,

2015 (Hacettepe University Faculty of Pharmacy – ILKO Pharmaceuticals), 2015

• American Association of Pharmaceutical Scientists (AAPS) Fellow Award, 2014

• Second Presentation Award, 49. National Neurology Congress, 2013.

• Best Presentation Award, 47 National Neurology Congress, 2011.

• Best Presentation Award, 44 National Neurology Congress, 2008.

• Scientific Merit Award, Turkish Pharmacists' Association, 2007.

• Hacettepe University Scientific Award, 2007.

• Hacettepe Technopark Inc. Project Competition Interfarma Life Science and

Technology, Second Award, 2007.

• Oral Presentation (1st winner award), National Neurology Congress, 2008.

• Hacettepe University Research Group Achievement Award, 1998-1999

Patents

• P.P.DeLuca, Y.Çapan, B.H. Woo, Stable polypeptide-comprising DNA complexes and methods of microsphere preparation for plasmid DNA delivery 11.03.1998

• Muderrisoglu, A., Capan, Y., Hincal, A. A., Ciftci, K.,

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Sustained Release Lithium Carbonate Tablets and Method for Preparing the Same. EP0471100A1, 1992

Memberships in Professional Organizations

• President of the Alumni Association of Faculty of Pharmacy, Hacettepe University, 1992- 1998

• Head of Hacettepe University, Pharmaceutical and Biopharmaceutical Sciences Technology Application and Research Center (FATUM), 2007-

• Member of the American Association of Pharmacetical Scientists

• Member of the Assoc. of Pharmaceutical Sciences of Ankara

• Member of the Turkish Pharmaceutical Technology Scientists' Association (TUFTAD)

• Member of the Turkish Pharmacists' Association (TEB)

• Member of the Pharmacist's Chamber of Ankara (AEO)

• Member of the Controlled Release Society (CRS)

• Member of the FIP Board of Pharmaceutical Sciences (FIP)

• Member of the AAPS Bioequivalance and Generic Pharmaceuticals Joint Focus

Group

• Member of the AAPS In Vitro Release & Dissolution Testing Focus Group

Symposia Organized

• International Pharmaceutical Technology Syposium-IPTS - Organizing Committee Member and Vice Chairman (1982-2008) - Chairman (2010) - Member of the Organizing Committee (2010-2016)

• Inernational Symposium on Microencapsulation Antalya/Turkey - Chairman (2011)