Primary and Primary and secondary secondary

tuberculosistuberculosis

Lecturer: Ph.D Lecturer: Ph.D M.G.DolynskaM.G.Dolynska

Primary tuberculosisPrimary tuberculosis

Developing in non-Developing in non-sensibilized sensibilized organismorganism

Non-specific reaction Non-specific reaction predominancepredominance

Exudation more Exudation more typicaltypical

Coincidence with the Coincidence with the early period of early period of tuberculosis tuberculosis infectioninfection

Bacteremia, Bacteremia, bacterilimphiabacterilimphia

HematogenicHematogenic disseminationdissemination

Lymphatic vessels and Lymphatic vessels and nodes involvementnodes involvement

Secondary tuberculosisSecondary tuberculosis

Developing in Developing in sensibilized sensibilized organismorganism

Specific reaction Specific reaction predominancepredominance

Proliferation and Proliferation and tissue decay are tissue decay are more typicalmore typical

No lymphatic systemNo lymphatic system involvementinvolvement

Primary tuberculosis clinical Primary tuberculosis clinical formsforms

Tubercle bronchodenitisTubercle bronchodenitiso Tumor likeTumor likeo InfiltrativeInfiltrative Primary complexPrimary complex Prelocal form of TBPrelocal form of TB

Secondary tuberculosis Secondary tuberculosis evolutionevolution

Focal (nidus) TBFocal (nidus) TB

The mildest limited lung TB The mildest limited lung TB clinical form which is clinical form which is characterized by the characterized by the appearance of single or appearance of single or several nidi (opacity with the several nidi (opacity with the diameter up to 1 cm in diameter up to 1 cm in diameter) in one or more diameter) in one or more segments of one or both lungs segments of one or both lungs with predominantly productive with predominantly productive type of the inflammation and type of the inflammation and slow torpid progression.slow torpid progression.

Infiltrative TBInfiltrative TB

The expansive lung TB clinical The expansive lung TB clinical form which is characterized by form which is characterized by the appearance of different the appearance of different size and shape lesions in one size and shape lesions in one or more segments of one or or more segments of one or both lungs with predominantly both lungs with predominantly exudative type of the exudative type of the inflammation and strong trend inflammation and strong trend to the rapid progression and to the rapid progression and decay.decay.

Infiltrate typesInfiltrate types

Infiltrate typesInfiltrate types

Caseous pneumoniaCaseous pneumonia

An acute TB form An acute TB form with the decay with the decay predominance predominance and severe and severe progressive progressive coursecourse

TuberculomaTuberculoma

The inflammative focus The inflammative focus limited by connective limited by connective tissue capsuletissue capsule

Fibrous-cavernous Fibrous-cavernous tuberculosistuberculosis

The chronic destructive clinical The chronic destructive clinical TB form characterized by the TB form characterized by the presence of the old fibrous presence of the old fibrous cavity (cavern) in the lung cavity (cavern) in the lung tissue surrounded by tissue surrounded by extended fibrosis and extended fibrosis and satellite nidisatellite nidi

Cirrhotic lung tuberculosisCirrhotic lung tuberculosis

The chronic destructive clinical The chronic destructive clinical TB form characterized by the TB form characterized by the predominant cirrhosis in the predominant cirrhosis in the lung tissue with the lung tissue with the embedded cavitations insideembedded cavitations inside

Secondary tuberculosis Secondary tuberculosis evolutionevolution

Miliary tuberculosisMiliary tuberculosis

Generalized TB Generalized TB clinical form with clinical form with the hematogenic the hematogenic type of type of dissemination dissemination and acute and acute coursecourse

Sub-acute disseminated Sub-acute disseminated tuberculosistuberculosis

Bilateral lung injury Bilateral lung injury with predominant with predominant affecting upper affecting upper lobes and trend for lobes and trend for destructive destructive progressive courseprogressive course

Chronic disseminated Chronic disseminated tuberculosistuberculosis

Disseminated lung Disseminated lung injury with the injury with the wavy coursewavy course and and progressive alveoli progressive alveoli substitution by substitution by connective tissueconnective tissue