How to Reverse

Pre-Diabetes

and Avoid

Diabetes

Pouya Shafipour, MDWellesley MedicalLos Angeles, CA

First the Good News! At the end of this presentation you will have a

clear understanding of the following:

You can lose excess weight in a healthy way

and reach your ideal weight

You can feel better than you have in a long

time

You can do this through safe and effective

dietary changes

You will learn how to maintain your weight

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In this talk we will cover:

The Problem

The Causes

The Solution

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An example of the Good news!

• RO 5’2” female, age 40

• 50 pounds overweight

• Size 14

• Frequent Headaches

• Nausea

• Insomnia

• Chronic Fatigue

• Borderline Diabetic

•6 months later

• 50 pounds loss

•Size 6

•frequent dizzy spells gone

•headaches gone

•nausea gone

•Dizzy spells gone

•Blood sugar balanced

•Great sleep

•Lots of energy!

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Now the Bad News!

• When it comes to Dieting and Weight loss in the US, We are confused

• Our current weight problem is not a result of lack of effort by the American Public.

• With over 6000 diets available and the contradictory “scientific evidence”, it would be a miracle if Americans were not confused

• Following the wrong plan, no matter how hard you try, will get poor results.

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The ProblemAmerica is Overweight and Obese

According to the CDC 1 out of 4 people

Are either Pre-Diabetic or Diabetic?

Oct 2010 CDC Estimates

By 2050 up to a third of the population diabetic

57 Million Americans Pre-Diabetic.

24 Million Americans Diabetic.

7th cause of Death in 2007

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More Statistics

Over 400,000 Deaths from Obesity year.

74% of Adult Americans are

Overweight/Obese

Since 1980 number of Overweight

Americans has doubled

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The Epidemic

Over the next 24 hours

2200 diabetics will be diagnosed

512 diabetics will die

66 diabetics will go blind

77 diabetics will develop end stage kidney

disease

153 will have diabetes related amputations

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Overweight and Obesity

Cancer Stats in U.S.

90,000 Cancer Deaths

14% of all Male Cancer

20% of Female Cancers

American Cancer Society*

*estimates excess weight

contributes to 33-50% of

women!

Heart Disease in

U.S.

Since 1984 more female deaths,

than male.

512,000 female Deaths

447,000 male Deaths

10,000 women under 50

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Health Effects of Being Overweight/Obese

• Type II Diabetes

• Heart disease

• High B.P., Heart Attack

• Stroke, Arthritis

• Pancreatitis

• Infertility, Birth Defects

• Carpal T.S., Low Back Pain

• Impaired Immune Response

• Impaired Resp. Disorders

• Fatigue, Fatigue and more...

• Gall Bladder D., Gout

• Menstrual disorders

• Menopausal hot flashes

• Insomnia, Sleep Apnea

• Depression, Reflux

• Surgical Complications

• Pain, Urinary Incontinence

• Chronic Ven. Insufficiency

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Cancers and Obesity

Esophagus

Pancreas

Colon and rectum

Breast (after menopause)

Endometrium (lining of the uterus)

Kidney

Thyroid

Gallbladder

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These Statistics Represent:

Quantity & Quality of Human Life Severely

Diminished by this one condition

Meaning Quantity in Years Lost

Quality of Life 24 hours, 7 days a week

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Why is There an Epidemic of

Diabetes and Obesity?

Falsehoods Exposed

“Its in my genes – I am doomed to get it”

“It is out of my control”.

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Causes of Diabetes & Obesity

• Unhealthy Eating Habits

• Excessive Weight (Abdominal Fat)

• Lack of Adequate Nutrients

• Lack of Exercise

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Changes in Our Eating Habits

Sugar intake 1900, 2-4 lbs. of

Sugar/person/year

Sugar intake 1999, 158 lbs./person/year

Refined Grain intake from late 1970’s thru

2000 has increased by 60 lbs. per year

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French vs American Diet

Late 20th Century French Diet was

higher in fat, had equal amounts of

meat and fish, 4X's as much butter

and cheese, and they had 60% less

Heart Disease than the US.

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More About Fats

From the mid 1980’s to mid 1990’s, the % of daily calories from Fat in the American Diet, decreased from 40% to 33%, while obesity in increased significantly

From 1910 to 1970, Heart Disease escalated from almost non-existent to # 1 cause of death. During this time the intake of Animal & Butter fat significantly decreased, dietary cholesterol did not increase, while sugar intake increased dramatically

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How do we Gain FAT?

Let’s look at the common scenario of fat

gaining that takes place, slowly but surely

over time, from too many carbs, too many

“empty calories”.

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When blood sugar exceeds a certain level

the body converts it to fat and stores it.

High Carb

Meal

Fat

Storage

Fat

Storage

Fat

Storage

Fat

Storage

Low Blood sugar

Symptoms

Next Carb Fix

Next Carb Fix

Next Carb Fix Next Carb Fix

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Insulin and GlucagonInsulin

• lowers elevated blood sugar.

• shifts our metabolism into storage mode

• removes dietary fat from blood and transports it into fat cells.

• Increases body's production of cholesterol

• causes the kidneys to retain fluid

• stimulates the release of eicosanoids.

Glucagon

• shifts metabolism into burning

mode

• turns fat into blood sugar for

energy use.

• Decreases body’s production of

cholesterol

• causes the kidneys to release

excess fluid.

• stimulates the release of

eicosanoids.

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The Eicosanoids

Insulin promoted

• Promote platelet

aggregation

• Promote vasoconstriction

• Depress Immune Response

• Are Pro-Inflammatory

• Increase Pain Transmission

Glucagon promoted

• Inhibit platelet aggregation

• Promote vessel opening

• Stimulate Immune Response

• Are Anti-Inflammatory

• Decrease Pain Transmission

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Where Does the Sugar come From?

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Think about the foods you love?Are they healthy choices?

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Refined Sugar

Sodium

Saturated Fat

Minerals,

Vitamins,

& anti-oxidants

Probiotics

Omega-3

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Out of Control Portion Size

Hamburger 2.8oz – 4.30oz 50% inc in calories

French Fries 2.4oz – 7.00oz, 10x inc in calories

Chocolate Bar 2.0oz – 7.00oz, 3x inc in calories

Coca Cola 6.5oz – 16.0oz, 2x inc in calories

Popcorn 3cups – 21cups, 10x inc in calories

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“If there is one thing that could bankrupt America, it’s health care.

And it’s out of control!”

David Walker, GAO – Presidential Forum on Aging

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The Status Quo

Not

Sustainable.

33% Diabetic - CDC!

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So, How do We

Solve this Problem?

The Bad News is:

There is No Magic Pill to solve

this problem.

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What Does not Work• Natural Stimulants”, i.e. Ephedra and the

many other “Fat Blockers”, “Carb Blockers”, “sleep your way to weight Loss, dont change your lifestyle” products.

• Prescription Medications for Weight Loss, remember Fen, Phen?

• Lastly,“it is not the fault of your Genes”. When we take care of the body in the way it is designed to be cared for, it performs wonderfully and loses weight steadily.

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Really Good News

All of these Statistics are

PREVENTABLE

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This Problem is Solvable

We have a very clear path to successfully

solving this…

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It is not about a Diet

It is about a system!

A System Structured for

Success

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What Most People Do Not Know

Pre-Diabetic for Years before Diabetic.

Pre-Diabetes is Reversible.

Healthcare System “Kicks in” After Diabetic.

Diabetic Medication only helps 12% of YOU!

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Diagnosis of Diabetes

Fasting Blood Sugar >= 126

HgbA1C>= 6.5%

2 Hr Glucose Tolerance Test at or above 200

Random Blood sugar >= 200

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Diagnosis of Pre-Diabetes

Fasting Blood Sugar 100-125

HgbA1C 5.7-6.4%

2 hour Glucose Tolerance Test 140-199

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Conventional Treatment of

Diabetes

• ADA Diet: High Carb/Low Fat

• Exercise

• Drugs: OHA, Insulin, Statins, blood pressure meds

• Percentage of Patients Under MD Care who achieve

- LDL Cholesterol <70

- BP </=130/80

- A1C <7%

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How to Reverse Diabetes

Prevent Pre-Diabetes

• Standard of Care – Waiting to Become a DIABETIC

• Become Aware of Unhealthy Blood Sugar

• Make Small Changes in Food Habits

• Prevent Diabetes & Pre-Diabetes

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Program of Reversal

• Abdominal Fat Loss

• Develop Healthy Food Habits

• Nutritional Deficiencies Supported

• Exercise

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Abdominal Fat Reversal

Establish a Bio-chemical State to Target:

ABDOMINAL FAT

Abdominal Fat = Development of Insulin Resistance & Tumor Formation

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Abdominal Fat Study

Excess body weight in combination with

physical inactivity is a major determinant

for the development of insulin resistance

with associated hyperglycaemia and

hyperinsulinaemia and further leads to

tumour development.”

Arch Physiol Biochem. 2009 May;115(2):86-96. Obesity related hyperinsulinaemia and hyperglycaemia and cancer development. Becker S, Dossus L, Kaaks R.

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Healthy Food Habits• Understand Food Habit Impact on Blood

Sugar

• Make the 20/80 Flip

• Minimize Foods that Induce Allergies/Sensitivities

• Ensure Adequate Intake of Protein with Meals

• Maintain 3 Meals a Day – Never Miss Breakfast

• Snack Between Meals

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Nutritional Deficiencies

• Typical Diabetic Mineral and Vitamin

Deficiencies

• Chromium, Magnesium, Zinc, EFA,

Selenium, B Vit, CoQ-10, alpha

lipoic acid, and Vit E

• Specialized Supplements to Improve

Pancreatic beta cell function

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Exercise

• Daily 30 minutes of movement for Heart Health

• 60 minutes of exercise for weight maintenance

• Family Exercise very important to prevent childhood obesity

• Non-Exercise Activity Thermogenesis(NEAT)

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Summary

• Rate of Obesity, Diabetes, and pre-Diabetes has

dramatically increased in the past 20 years and

affects at least 1 out of 4 of the population.

• Our consumption of “sugar” over the past 100

years has increased by over 50 times.

• “Adult onset diabetes” or type II diabetes has

begun to afflict eight and ten-year-old children.

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Conclusion

• Screen Yourself for:

(Diabetes/Pre-Diabetes/Unhealthy Blood Sugar)

Take Action:

If Fasting Blood Sugar Above 95

Simple Changes can Prevent Pre-diabetes

Diabetics Reduce or Eliminate use of Meds

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Simple Action Steps

Decrease or eliminate intake of processed sugar that include:

(High fructose corn syrup), soda, & juices.

Minimize intake of refined starches (bagels, bread, potatoes, corn, rice, or pasta) since they are simply sugars in disguise.

Consume most of your calories from Meats, Dairy, Fruits, & Vegetables.

Adapt to a healthy lifestyle of daily exercise and healthy eating habits.

Take action to keep waist size (abdominal fat) within healthy range.

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For more information please visit us at

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Or Call us at (310) 400-5565