Polyintell

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“New tools for extraction, purification and detection based on intelligent polymers“ POLYMERS DESIGNER Be Selective www.polyintell.com

Transcript of Polyintell

Page 1: Polyintell

“New tools for extraction, purification and

detection based on intelligent polymers“

POLYMERS DESIGNER

Be Selective

www.polyintell.com

Page 2: Polyintell

Founded in 2004, POLYINTELL develops and

manufactures new products for sample

preparation, selective extraction and detection of

specific target analytes.

Offers

•Catalog products

•Custom-made products

Application fields

• Food safety

• Diagnostic

•Pharmaceutical R&D

COMPANY PROFILE

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•Molecularly Imprinted

Polymers (MIP)

•Intelligent Polymers

•3 specialized teams:

Organic chemistry

Polymer chemistry

Analytical chemistry

• Patent portfolio : 6 patents

STRONG IN HOUSE KNOW-HOW

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FACILITIES & EQUIPMENT

• Located at Pharma Parc II, Val de Reuil , 90km from

Paris - FRANCE

• 600m2 including fully equipped laboratories

• On site production unit

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TECHNOLOGY

Self-assembly Polymerization Target

extraction

BENEFITS

•High affinity and selectivity

•Robust and stable materials

•Fast development &cost effective

New Molecular Recognition Phase

Based on Molecularly Imprinted Polymers

Molecular Recognition

Materials

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From material to products

AFFINIMIP®SPE

Crushed monoliths

Meso-, macro-porous : from 2nm to 200nmMicropores < 2nm

Microscopic image

Particles size :• 30 -80 µm• 50-60 µm• 8-10 µm

Porous micro-beads

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AFFINIMIP® Selective Extraction Cartridges

For sample preparation

Loading Washing steps

Analyte elutionHigh recovery and selectivity!

Catalog products : AFFINIMIP®

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Applications of AFFINIMIP ® SPE

Coming soon :

•AFFINIMIP® Phenolic compounds

•AFFINIMIP® Estradiol

Mycotoxins:

• AFFINIMIP® Zearalenone

• AFFINIMIP® Ochratoxin A

•AFFINIMIP® Patulin (New !)

Food safetyDiagnostics

Pharma R&D

• AFFINIMIP® Catecholamine

•AFFINIMIP® Metanephrine

• AFFINIMIP® Tamoxifen

•AFFINIMIP® GSH

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AFFINIMIP® Zearalenone

AFFINIMIP® Zearalenone selective extraction cartridges

•Perfect clean-up for trace analysis of ZON from maize and wheat

Application

Chromatograms of maize sample spiked with zearalenone at level of

85 μg.Kg-1 before clean-up and after extraction through AFFINIMIP® SPE.

Zearalenone

Column Hypersil Gold 150 x 2.1 mm, 0.2 mL/min, Vinj = 10 µL, lex =275 nm - lem=450 nm, 60-40 MeOH-H2O

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AFFINIMIP® Ochratoxin A

AFFINIMIP® Ochratoxin A selective extraction cartridges

•Perfect clean-up for trace analysis of OTA from maize and wheat

Application : selective extraction of Ochratoxin A from wheat

Ochratoxin A

—— AFFINIMIP® SPE

—— Before clean-up

Column Hypersil Gold 150 x 2.1 mm, 0.2 mL/min, Vinj = 10 µL, lex =333 nm - lem=460 nm, 60-40 MeOH-H2O (1%AA)

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AFFINIMIP® Patulin New!

AFFINIMIP® Patulin selective extraction cartridges

•Simple sample preparation

•Perfect clean-up system for trace analysis of Patulin

•Applicable to several apple derived matrices

Application : selective extraction of Patulin

Patulin

—— AFFINIMIP® SPE

—— Before clean-up

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High recovery and selectivity!

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Custom-made product

Customers: Sanofi-Aventis, Servier,

GSK, Roche, Pfizer, …

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BE SELECTIVE

www.polyintell.com