Paul W. Stewart - UNC Gillings School of Global Public...

Last revised March 1, 2012 1

Paul W. Stewart

Business Address 3105G McGavran-Greenberg Hall Department of Biostatistics UNC-CH School of Public Health Campus Box 7420 Chapel Hill, NC 27599-7420 919-966-7276 [email protected] Education 1977-1981 PhD Biostatistics. The University of North Carolina at Chapel Hill. Thesis on a type III bivariate t-distribution for analysis of cross-over designs. Supporting program in Epidemiology and Biomedical Engineering. 1975-1977 MS Statistics. The University of North Carolina at Chapel Hill. Thesis on time-series models for digital analysis of human speech. 1971-1975 BS Mathematics. Furman University, Greenville, South Carolina. Minor in Chemistry, electives in the Medical Sciences and in Visual Arts. Professional Experience 1999-present Research Associate Professor, UNC Biostatistics Department 2016-present UNC Scientific Review Committee 2009-present UNC Scientific Review Subcommittee of the SOM IRB Committee 1982-1998 Research Assistant Professor, UNC Biostatistics Department 1982-1982 Visiting Research Assistant Professor, UNC Biostatistics Department 1981-1982 Graduate Research Trainee, Pre-Doctoral Award, Directed by Dr. C. E. Davis. UNC Biostatistics Department. 1978-1981 Graduate Research Assistant, CDC-UNC SENIC Project, Directed by Dr. R. J. Carroll and Dr. D. Quade, UNC Biostatistics Department. 1977-1978 Graduate Research Assistant, AID-UNC Guatemala Water and Sanitation Project, Directed by Dr. R. W. Helms, UNC Biostatistics Department. 1975-1977 Graduate Teaching Assistant, Training Grant, Directed by Dr. Ed Wegman, UNC Statistics Department.

Paul W. Stewart

September 12, 2016 Page 2

Honors 1997 US-EPA Scientific Achievement Award for Publication 1995 Delta Omega Honor Society for Public Health Professionals 1980-1981 NIH Training Grant 1979 Award for Best Paper on Linear Models at the 4th Annual Conference of SUGI Memberships International Biometric Society, Eastern North American Region (ENAR) American Statistical Association (ASA) Publication Officer of the ASA Section on Statistical Consulting (years 2007 and 2008) CTSA Key Function Committee for BERD (Biostatistics/Epidemiology/Research Design) Association of GCRC and CTSA Statisticians Association of CFAR Statisticians (2002-2008, Association founded by Paul Stewart in 2002) Publications 1. Books and Chapters Muller KE and Stewart PW (2006) Linear Model Theory: Univariate, Multivariate, and Mixed Models, Wiley Interscience, NY. 410 pages. Anderson JJB, Switzer BR, Stewart PW, Symons M (2004). “Nutritional Assessment: Analysis of Relationships Between Nutrient Factors and Bone Health.” Chapter 3 in Nutrition and Bone Health, Ed. by Michael F. Holick and Bess Dawson-Hughes. Stewart PW (2000), “Estimation and Comparison of Growth and Dose-Response Curves in the Presence

of Purposeful Censoring”. Book Chapter #10 in the Handbook of Statistics, Vol. 18: Bioenvironmental and Public Health Statistics, Sen PK and Rao (eds.). Elsevier Science Publishing Co., North-Holland / Elsevier, Amsterdam; New York. pp. 325-354.

Stamm JW, Disney JA, Beck JD, Weintraub JA, Stewart PW (1993). "The UNC Caries Risk Assessment Study: Final Results and Some Alternative Modeling Approaches," pages 210-234, in Cariology for the Nineties, edited by Bowen WH and Tabak LA. Rochester, New York: University of Rochester Press.

Paul W. Stewart


2. Refereed Publications: Statistical Methods Moore CG, Carter R, Nietert PJ, Stewart PW (2011). Recommendations for Planning Pilot Studies in

Clinical and Translational Research, Clinical and Translational Science 4(5):332-337. PMID 22029804.

( brief news article about this publication: Willyard C. (2011) Biostatisticians call for more scientifically rigorous pilot studies Nature Medicine 17, 1531-1531. www.nature.com/nm/journal/v17/n12/full/nm1211-1531b.html.) Edwards LJ, Stewart PW, MacDougall JE*, Helms RW (2006). A method for Fitting Regression Splines

with Varying Polynomial Order in the Linear Mixed Model. Statistics in Medicine, 25(3): 513-527. Bowman, FD*, Stewart PW, Sen PK, Helms RW (2004). Making Inferences about Projected

Completors in Longitudinal Studies. Journal of Biopharmaceutical Statistics 14(4): 947-967. Jiroutek MR, Muller KE, Kupper LL, Stewart PW (2003). A New Method for Choosing Sample Size

for Confidence Interval Based Inferences. Biometrics, 59: 580-590. Edwards LJ, Stewart PW, Muller KE, Helms RW (2001) Linear Equality Constraints in the General

Linear Mixed Model. Biometrics 57, 1185-1190. Stewart PW (1991), Tracking Analysis for Inconsistently Timed Longitudinal Data, Statistics in

Medicine, 11, 2027-2040. Stewart PW (1991). The graphical advantages of finite interval confidence band procedures.

Communication in Statistics, A20, No. 12, 3975-3994. Stewart PW, Stamm JW, (1991). Classification tree prediction of caries using clinical, microbiological

and interview Data, Journal of Dental Research, 70(9), 1239-1251. Stewart PW, Helms RW (1989). Evaluating The Distribution Function Of A Bonferroni Test Statistic

From A Type III Bivariate T Distribution, Journal of Communications in Statistics, A18, No.2, 461-478.

Stewart PW (1989). Extension of the Harrell-Davis quantile estimator to finite populations,

Communications in Statistics, A18, No. 3, 853-876. Stewart PW (1987). Line-segment confidence bands for repeated measures, Biometrics, 43, 629-640. Stewart PW (1981). Application Of A Bivariate T Distribution To Hypotheses Testing In Crossover

Experiments, Doctoral Dissertation, UNC-CH, December 1981. Institute of Statistics Mimeo Series. The University of North Carolina, Chapel Hill, NC.

--------------------------- * students mentored

Paul W. Stewart


3. Refereed Publications: Statistical Application Development and Tutorial Articles Stewart PW, Cachafeiro A, Napravnik S, Eron JJ Jr, Frank I, van der Horst C, Bosch RJ, Bettendorf D,

Bohlin P, Fiscus SA. (2010) Performance Characteristics of the Cavidi ExaVir Viral Load Assay and the Ultra Sensitive P24 Assay Relative to the Roche Monitor HIV-1 RNA Assay. 1

Journal of Clinical Virology. 49; 198–204. PMID 20832356, NIHMS 235094

McDonnell WF, Stewart PW, Smith MV (2013). Ozone exposure-response model for lung function changes: an alternate variability structure. Inhalation Toxicology. 25(6):348-353. PMID 23742111

McDonnell WF, Stewart PW, Smith MV, Kim CS, Schelegle ES (2012), Prediction of Lung Function Response for Populations Exposed to a Wide Range of Ozone Conditions.

Inhalation Toxicology 24(10):619-633. PMID 22906168 McDonnell WF, Stewart PW, Smith MV (2010) Prediction of ozone-induced lung function responses in

humans. Inhalation Toxicology 22(2):160-168. PMID19778178 McDonnell WF, Stewart PW, Smith MV (2009) Modification of a Human Ozone Exposure-Response

Model and Evaluation of Its Performance in Predicting Mean Changes in FEV1 in Independent Data. Inhalation Toxicology 22(2); 160-168.

McDonnell WF, Stewart PW, Smith MV (2007). The temporal dynamics of ozone-induced FEV1

changes in humans: an exposure-response model. Inhalation Toxicology 19(6-7): 483-494. McDonnell WF, Stewart PW, Smith MV, Pan WK*, Pan J (1999) Ozone-induced Respiratory Symptoms:

Exposure-Response Models and Association with Lung Function. European Respiratory Journal, 14: 845-853.

1 In the area of HIV-associated assay research, published comparisons of assay methods had typically relied on inferior statistical methods. The above article explicated innovative use of best statistical methods and strategies within the context of assay comparisons. Such comparisons are of great interest to many investigators.

Paul W. Stewart


4. Refereed Publications: Collaborative Biomedical Research Feins RH, Burkhart HM, Conte JV, Coore DN, Fann JI, Hicks GL Jr, Nesbitt JC, Ramphal PS, Schiro SE,

Shen KR, Sridhar A*, Stewart PW, Walker JD, Mokadam NA. (2016) Simulation-Based Training in Cardiac Surgery. Ann Thorac Surg. VV:ppp-ppp. PMID 27570162 (* biostatistics student)

2016 Aug 20. pii: S0003-4975(16)30773-1. doi: 10.1016/j.athoracsur.2016.06.062. [Epub ahead of print] Sterling RK, Kuo A, Rustgi VK, Sulkowski MS, Stewart TG*, Fenkel JM, El-Genaidi H, Mah'moud MA,

Abraham GM, Stewart PW, Akushevich L, Nelson DR, Fried MW, Di Bisceglie AM (2015). Virological outcomes and treatment algorithms utilization in observational study of patients with chronic hepatitis C treated with boceprevir or telaprevir.

Aliment Pharmacol Ther. 41(7):671-85. PMID: 25627020 (* biostatistics student) Ferslew BC, Xie G, Johnston CK, Su M, Stewart PW, Jia W, Brouwer KL, Sidney Barritt A 4th (2015).

Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis. Dig Dis Sci. 60(11):3318-28. PMID: 26138654 Ferslew BC, Johnston CK, Tsakalozou E, Bridges AS, Paine MF, Jia W, Stewart PW, Barritt AS 4th,

Brouwer KL (2015).Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis. Clin Pharmacol Ther. 97(4):419-27. PMID: 25669174

Hill AM, Stewart PW, Fung MK, Kris-Etherton PM, Ginsberg HN, Tracy RP, Pearson TA, Lefevre M, Reed

RG, Elmer PJ, for the DELTA Investigators. (2014) Monthly haemostatic factor variability in women and men. European Journal of Clinical Investigation. 44(3):309-318. PMID: 24382103

LaMantia MA, Stewart PW, Platts-Mills TF, Biese KJ, Forbach C, Zamora E, McCall BK, Shofer FS, Cairns

CB, Busby-Whitehead J, Kizer JS. (2013) Predictive value of initial triage vital signs for critically ill older adults. Western Journal of Emergency Medicine. 14(5):453-460. PMID: 24106542

Köck K, Ferslew BC, Netterberg Ida, Yang K, Urban TJ, Swaan PW, Stewart PW, Brouwer KLR (2014).

Risk factors for development of cholestatic drug-induced liver injury: Inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4.

Drug Metabolism and Disposition. 42(4):665-674. PMID: 24154606 Yang K, Pfeifer ND, Hardwick RN, Yue W, Stewart PW, Brouwer KLR (2014) An experimental approach

to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown.

Molecular Pharmaceutics. 11(3):766-775. PMID: 24410402 Gribbin MJ, Chi YY, Stewart PW, Muller KE (2013). Confidence regions for repeated measures

ANOVA power curves based on estimated covariance. BMC Medical Research Methodology. 13(1):57. PMID 23586676 Dong B, Stewart PW, Egan TM (2013). Postmortem and ex vivo carbon monoxide ventilation reduces

injury in rat lungs transplanted from non-heart-beating donors. Journal of Thoracic Cardiovascular Surgery. S0022-5223(12):01382-7. PMID 23260460 Tian Z, Dong B, Blackwell JW, Stewart PW, Egan TM (2013). Effect of a vascular endothelial cadherin

antagonist in a rat lung transplant model. Ann Thoracic Surg. 95(3):1028-33. PMID 23333062

Paul W. Stewart


Ilic K, Hawke RL, Thirumaran RK, Schuetz EG, Hull JH, Kashuba AD, Stewart PW, Lindley CM, Chen

ML (2013). The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans. Drug Metab Dispos. 41(3):575-581. PMID 23238783

Dosal JC, Stewart PW, Lin J-A*, Williams CS, Morrell DS (2014), Cantharidin for Treatment of

Molluscum Contagiosum: A Prospective, Double-Blinded, Placebo-Controlled Trial. Pediatric Dermatology. 31(4):440–449. PMID 22897595 (* biostatistics student) Kipp AM, Pungrassami P, Stewart PW, Chongsuvivatwong V, Strauss RP, VanRie A (2011). Study of tuberculosis and AIDS stigma as barriers to tuberculosis treatment adherence using

validated stigma scales. Int J Tuberc Lung Dis. 15(11):1540-1545. PMID 22008770 Noah TL, Ivins SS, Abode KA, Stewart PW, Michelson PH, Harris WT, Henry MM, Leigh MW. (2010) Inhaled versus systemic antibiotics and airway inflammation in children with cystic fibrosis

and Pseudomonas. Pediatric Pulmonology. 45(3):281-290. PMID 20146365 Joy MS, Boyette T, Hu Y, Wang J, La M, Hogan SL, Stewart PW, Falk RJ, Dooley MA, Smith PC

(2010) Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid PK in glomerulonephritis.

European Journal of Clinical Pharmacology (2010) 66:1119–1130. PMID 20567810 Pungrassami P, Kipp AM, Stewart PW, Chongsuvivatwong V, Strauss RP, Van Rie A. (2010)

Tuberculosis and AIDS stigma among patients who delay seeking care for tuberculosis symptoms. International Journal of Tuberculosis and Lung Disease 14(2):181-187. PMC 2875178 PMID 20074409

Napravnik S, Cachafeiro A, Stewart PW, Eron JJ Jr, Fiscus SA. (2010) HIV-1 viral load and phenotypic

antiretroviral drug resistance assays based on reverse transcriptase activity in comparison to amplification based HIV-1 RNA and genotypic assays.

J Clin Virol. 47(1):18-22. Epub 2009 Nov 5. PMID 19896416 Van Rie A, Dow A, Mupuala A, Stewart PW (2009) Neurodevelopmental trajectory of HIV-infected

children accessing care in Kinshasa, Democratic Republic of Congo. J Acquir Immune Defic Syndr. 52(5):636-42. PMID 19730268 Rosen DL, Schoenbach VJ, Wohl DA, White BL, Stewart PW, Golin CE (2009). Characteristics and

behaviors associated with HIV infection among inmates in the NC prison system. American Journal of Public Health. 99(6):1123-1130. PMID 19372527 Rosen DL, Schoenbach VJ, Wohl DA, White BL, Stewart PW, Golin CE. (2009). An evaluation of HIV

testing among inmates in the North Carolina prison system. American Journal of Public Health. 99 Suppl 2: S452-S459. PMID 19797758 Mukherjee N, Morrell DS, Duvic M, Stewart PW, Goldsmith LA. (2009) Attitudes of dermatologists in

the southeastern United States regarding treatment of alopecia areata: a cross-sectional survey study. BMC Dermatol. 12:9-11. PMID 19909522 Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu T-S*, Stabler SP, Allen RH, Zeisel SH (2007).

Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 85(5): 1275-1285. (* biostatistics student)

Paul W. Stewart


Dumond JB, Yeh RF, Patterson KB, Corbett AH, Jung BH, Rezk NL, Bridges AS, Stewart PW, Cohen MS, Kashuba AD. (2007) Antiretroviral drug exposure in the female genital tract: implications

for oral pre- and post-exposure prophylaxis. AIDS 21(14): 1899-1907. Pilcher CD, Joaki G, Hoffman IF, Martinson FEA, Mapanje C, Stewart PW, Powers KA, Galvin S,

Chilongozi D, Gama S, Price MA, Fiscus SA, Cohen MS, for the UNC Project in Malawi (2007). Amplified Transmission of HIV-1: Comparison of HIV-1 Concentrations in Semen and Blood During Acute and Chronic Infection AIDS 20;21(13): 1723-1730.

Richey LM, George JR, Couch ME, Kanapkey BK, Yin X, Cannon T, Stewart PW, Weissler MC,

Shores CG. (2007) Defining cancer cachexia in head and neck squamous cell carcinoma. Clinical Cancer Research. 13(22 Pt 1): 6561-6567. Berglund L, Lefevre M, Ginsberg HN, Kris-Etherton PM, Elmer PJ, Stewart PW, Ershow A, Pearson TA, Dennis BH, Roheim PS, Ramakrishnan R, Reed R, Stewart K, Phillips KM, for the DELTA Investigators. (2007) Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects

with a high metabolic risk profile: studies in the fasting and postprandial states. American Journal of Clinical Nutrition. 86(6):1611-1620. Golin CE, Earp J, Tien H-C*, Stewart PW, Porter C, Howie L. (2006) A 2-arm, randomized, controlled

trial of a motivational interviewing-based intervention to improve adherence to antiretroviral therapy (ART) among patients failing or initiating ART.

J Acquired Immune Deficiency Syndrome. 42(1): 42-51. Watkins PB, Kaplowitz N, Slattery JT, Colonese CR, Colucci SV, Stewart PW, Harris SC. (2006)

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA 296(1): 87-93.

{#1 on the "50 Most Frequently Read Articles" list accessed from the web site during July 2006.} Watkins PB, Kaplowitz N, Colucci SV, Stewart PW, Harris SC. (2006) Reply: Acetaminophen and Aminotransferase Elevations. JAMA 296(23): 2798-2799. Mouly SJ, Matheny C, Paine MF, Lambda Smith G, Lamba J, Lamba V, Pusek SN, Schuetz EG, Stewart PW, Watkins PB (2005). Variation in oral clearance of saquinavir is predicted by

CPY3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5. Clinical Pharmacology Therapy, 78(6): 605-618. Napravnik S, Edwards D, Stewart PW, Stalzer B, Matteson E, Eron JJ Jr. (2005). HIV-1 Drug

Resistance Evolution Among Patients on Potent Combination Antiretroviral Therapy with Detectable Viremia. Journal of Acquired Immune Deficiency Syndrome. 40:34-40.

Paine MF, Ludington SS, Chen M-L, Stewart PW, Huang S-M, Watkins PB (2005). Do Men and

Women Differ in Proximal Small Intestinal CYP3A or P-Glygoprotein Expression? Drug Metabolism and Disposition 33: 426-433. Wohl DA, Zeng D, Stewart PW, Glomb N, Alcorn T, Jones S, Handy J, Fiscus S, Weinberg A, Gowda

D, van der Horst C (2005). Cytomegalovirus, Mortality and CMV End-Organ Disease Among Patients with AIDS Receiving Potent Antiretroviral Therapies.

Journal of Acquired Immune Deficiency Syndrome 38(5): 538-544.

Paul W. Stewart


Girdler SS, Maixner W, Naftel HA, Stewart PW, Moretz RL, Light KC. (2005) Cigarette smoking, stress-induced analgesia and pain perception in men and women. Pain. 114(3): 372-385. PMID15777863 Stephenson BL, Wohl DA, Golin CE, Tien H-C*, Stewart PW, Kaplan AH (2005) Effect of Release from Prison and Re-incarceration on the Viral Loads of HIV-infected individuals.

Public Health Reports 120:84-88. Mouly SJ, Matheny C, Paine MF, Lambda Smith G, Lamba J, Lamba V, Pusek SN, Schuetz EG, Stewart PW, Watkins PB (2005). Variation in oral clearance of saquinavir is predicted by CPY3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5. Clinical Pharmacology Therapy, 78(6): 605-618. Napravnik S, Edwards D, Stewart PW, Stalzer B, Matteson E, Eron JJ Jr. (2005). HIV-1 Drug Resistance Evolution Among Patients on Potent Combination Antiretroviral Therapy with Detectable Viremia. Journal of Acquired Immune Deficiency Syndromes. 40: 34-40. Paine MF, Ludington SS, Chen M-L, Stewart PW, Huang S-M, Watkins PB (2005). Do Men and Women Differ in Proximal Small Intestinal CYP3A or P-Glycoprotein Expression? Drug Metabolism and Disposition 33: 426-433. Wohl DA, Zeng D, Stewart PW, Glomb N, Alcorn T, Jones S, Handy J, Fiscus S, Weinberg A, Gowda D, van der Horst C (2005) JAIDS 38(5): 538-544. Girdler SS, Maixner W, Naftel HA, Stewart PW, Moretz RL, Kathleen CL (2005) Cigarette Smoking, Stress-Induced Analgesia and Pain Perception in Men and Women. Pain 114(3): 372-385. Stephenson BL, Wohl DA, Golin CE, Tien H-C*, Stewart PW, Kaplan AH (2005) Effect of Release from Prison and Re-incarceration on the Viral Loads of HIV-infected individuals. Public Health Reports 120:84-88. Pilcher CD, Tien HC, Eron JJ, Vernazza PL, Leu S-Y, Stewart PW, Goh LE, Cohen MS (2004). Brief but Efficient: Acute HIV Infection and the Sexual Transmission of HIV. Journal of Infectious

Disease. 189:1785-1792. Shefali MK, Paine MF, Stewart PW, Watkins PB (2004) 6’7’-Dihydroxyberamottin Contributes to the

Grapefruit Juice Effect. Clinical Pharmacology and Therapeutics 75: 569-579. Givens RC, Lin YS, Dowling ALS, Thummel KE, Lamba JK, Schuetz EG, Stewart PW, Watkins PB

(2003). CYP3A5 Genotype Predicts Renal CYP3A Activity and Blood Pressure in Healthy Adults. Journal of Applied Physiology. 95: 1297-1300.

Lindesmith L, Moe CL, Marionneau S, Ruvoen N, Jiang X, Lindblad L, Stewart PW, LePendu J, Baric R (2003). Human Susceptibility and Resistance to Norwalk Virus Infection. Nature Medicine 9: 548 - 553.

Paul W. Stewart


Hoffman IF, Martinson FEA, Stewart PW, Chilongozi1 DA, Leu S-Y, Kazembe PN, Banda T, Dzinyemba W, Joshi1 P, Cohen MS, Fiscus SA (2003).

HIV-1 RNA in Breast Milk Components. Journal of Infectious Disease. 188: 1209-1212. Davenport ML, Punyasavatsut N, Stewart PW, Gunther DF. Savendahl L. Sybert VP. (2002) Growth failure in early life: an important manifestation of Turner syndrome. Hormone Research. 57(5-6):157-64. Quinlivan EB, Zhang C, Stewart PW, Komoltri C*, Davis MG, Wehbie RS (2002). Elevated Virus Loads Of Kaposi's Sarcoma-Associated Human Herpesvirus 8 Predict Kaposi's Sarcoma

Disease Progression, But Elevated Levels Of Human Immunodeficiency Virus Type 1 Do Not. Journal of Infectious Diseases, 185(12):1736-44. Quinlivan EB, Wang RX, Stewart PW, Komoltri C*, Regamey N, Erb P, Vernazza PL (2001).

Longitudinal sero-reactivity to human herpesvirus 8 (KSHV) in the Swiss HIV Cohort 4.7 years before KS. Journal of Medical Virology. (64):157-166.

Jere C, Cunliffe NA, Hoffman IF, Stewart PW, Kilaru K*, Boradhead RL, Molyneux ME, Hart CA,

Fiscus FA (2001). Plasma HIV Burden in Malawian Children Co-Infected with Rotavirus. AIDS 15(11): 1439-1442. Reed R, Stewart PW, Kris-Etherton PM, Pearson T, for the DELTA Investigators (2000). Effects of Menstrual Cycle on Lipids and Hemostasis. Metabolism. 49: 1101-1105. (Acknowledgment to Szu-Yun Leu, Biostatistics GRA.) Davenport ML, Punyasavatsut N, Gunther D, Savendahl L, Stewart PW (1999) Turner syndrome: a pattern of early growth failure. Acta Paediatr Suppl 88(433):118-21 Muhlebach MS, Stewart PW, Leigh MW, Noah TL (1999). Inflammatory Responses to Bacteria in Young Cystic Fibrosis and Control Patients. American Journal of Respiratory and Critical Care Medicine 160: 186-191. Dennis B, Champagne C, Ershow A, Karmally W, Kris-Etherton P, Phillips K, Stewart K, Stewart PW,

Van Heel N, Wang CH, Windhauser M, Farhat-Wood A, for the DELTA Investigators (1998). Diet Design for Multicenter Controlled Feeding Trials: DELTA I. Journal of the American Dietetic Association. 98(7): 766-776. Ginsberg H, Dennis B, Elmer P, Ershow AP, Lefevre M, Pearson T, Roheim P, Ramakrishnan R, Reed RG, Anderson N, Stewart K, Philllps K, Stewart PW, Kris-Etherton PK, for the DELTA Investigators (1998), Diet Effects on Lipids and Thrombogenic Activity: Effects of

Reducing Dietary Total and Saturated Fat on Plasma Lipids and Lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology, 18: 441-449. Lefevre M, Ginsberg HN, Kris-Etherton PM, Elmer PJ, Stewart PW, Ershow A, Pearson TA, Roheim PS, Ramakrishnan R, Derr J, Gordon D, Reed R, for the DELTA Investigators (1997). ApoE genotype does not predict lipid response to changes in dietary saturated fatty acids in a heterogeneous normolipidemic population. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2914-2923.

Paul W. Stewart


Herman-Giddens ME, Kotch JB, Browne DC, Ruina E, Winsor JR, Jung JW, Stewart PW (1997).

Childbearing Patterns in a Cohort of Women Sexually Abused as Children, Journal of Interpersonal Violence. 13(4): 504-513. McDonnell WF, Stewart PW, Andreoni S, Seal E Jr, Kehrl R, Horstman DH, Folinsbee LJ, Smith

MB (1997) Prediction of Ozone-induced FEV1 Changes: Effects of Concentration, Duration, and Ventilation. American Journal of Respiratory and Critical Care Medicine, 156: 715-722.

Quinlivan, EB, Ye D, Wehbie RS, Stewart PW, Flepp M, Vernazza PI. (1997) Kaposi's Sarcoma Patients in the Swiss HIV Cohort Study with and without Detectable Human Herpesvirus 8 in Peripheral Blood Mononuclear Cells, AIDS 11: 1893-1895. Kotch JB, DuFort V, Stewart PW, Fieberg J, McMurry M, O’Brian S, Ngui EM, Brennan M (1997).

Injuries Among Children in Home and Out-of-Home Care, Journal of Injury Prevention 3: 267-271. Kotch JB, Browne DC, Ringwalt CL, DuFort V, Ruina E, Stewart PW, Jung JW (1997). Stress, Social Support and Substantiated Maltreatment in the Second and Third Year of Life, Journal of Child Abuse and Neglect 21: 1025-1037. McDonnell WF, Stewart PW, Andreoni S, Smith MB (1995) Proportion of Moderately Exercising

Individuals Responding to Low-level, Multi-hour Ozone Exposure. American Journal of Respiratory and Critical Care Medicine, 152: 589-596. Kotch JB, Browne DC, Ringwalt CL, Stewart PW, Ruina E, Holt K, Lowman B, JW Jung (1995). Risk of Child Abuse and Neglect in a Cohort of Low Income Children. Journal of Child Abuse and Neglect, 19: 1115-1130. Henderson FH, Henry MM, Ivins SS, Morris R, Neebe EC, Leu S, Stewart PW (1995). Correlates of Recurrent Wheezing in School Age Children American Journal of Respiratory and Critical Care Medicine, 151: 1786-1793. Hillis SD, Weigle K, Miranda CM, McCann M, Bender D, Stewart PW (1995). Supplementary Feeding in Colombian Child-Care Centers and Growth Velocity, Pediatrics, 94: 1066-1069. Margolis MQ, Hunt RJ, Vann WF, Stewart PW (1994). Distribution of primary tooth caries in first-

grade children from two nonfluoridated US communities. Pediatric Dentistry, 16: 200-205. Henderson FH, Stewart PW, Voter KZ, Strope GL, Burchinal MR, Ivins SS, Morris R, Ou-Li Wang, Henry MM (1992). Respiratory allergy and the relationship between early childhood

lower respiratory illness experience and subsequent lung function American Review of Respiratory Disease, 145, 283-290 Strope G, Stewart PW, Henderson F, Henry M, (1991). Respiratory allergy and the relationship

between early childhood lower respiratory illness experience and subsequent lung function. American Review of Respiratory Disease, 144, 655-662. Stamm JW, Stewart PW, Bohannan HM, Disney JA, Graves RC, Abernathy JR (1991).

Paul W. Stewart


Risk Assessment for Oral Diseases, Advances in Dental Research, 5, 4-17. Scruggs RR, Stewart PW, Samuels MS, Stamm JW (1991). Clinical evaluation of seven anti-calculus dentifrice formulations, Journal of Clinical Periodontology, 13, 23-27. Stamm JW, Disney JA, Graves R, Cancro L, Payonk G, Stewart PW (1988). An Evaluation of six dentifrice formulations for anticalculus activity, Journal of Clinical Periodontology, 16, 101-111 Voter K, Henry M, Stewart PW, Strope G, Henderson F, (1987). Methacholine sensitivity and lung function related to pre-school lower respiratory illness in children in Chapel Hill, NC.

American Review of Respiratory Disease1, 137, 302-307. Carson JL, Collier AM, Hu SS, Smith CA, Stewart PW (1987). The appearance of compound cilia in

the nasal mucosa of normal human subjects following acute environmental exposure to sulfur dioxide. Environmental Research, 42, 155-165.

Glueck C, Laskarzewski P, Suchindran C, Chambless W, Stewart PW, Heiss H, Tyroler A (1986).

Progeny's lipid levels by parental mortality, Circulation. Part 2, 73, 51-61. Kwiterovich P, Stewart PW, for the LRC Investigators (1986). Detection of dyslipoproteinemia using

plasma total cholesterol and triglyceride levels, Circulation, Part 2, 73, 30-39. 5. Manuscripts in Review or in Revision Stewart PW, Benignus V ( ) “Nonlinear models for summary dose-response data.” Submitted to American Statistician and in revision. 14 pages. Enck SW, Stewart PW ( ). “Latent Class Linear Mixed Models: A General Approach with a Tutorial for

Clinical Researchers.” In revision for Statistics in Medicine. 23 pages. Stewart PW, Kaplan A ( ) “A Bernoulli Left-Censored Lognormal Mixture Model for Activity of the

Protease of HIV-1 as a Function of Amino Acid Characteristics”. In revision for Biometrics. 31 pages. Stewart PW, McDonnell WF, Smith MV ( ) “A compartmental model for ozone-induced lung

function responses.” In revision for JASA. 19 pages. Sigounas DG, Stewart PW, Kilpatrick M, Bullitt E, Smith JK, Ewend MG ( ) . “A New Measurement Criterion for Evaluation of Metastatic Brain Lesions.” Submitted to Journal of Clinical Oncology. 13 pages. Brown KC, Kashuba ADM, Stewart PW, Reddy YS, Jenkins AEJ, Paine MF, Schuetz EG, Lamba JK,

Strassburg CP, Watkins PB ( ). “Effect of sex and polymorphisms in CYP3A5, UGT1A4 and ABCB1 on the Erythromycin Breath Test (ERMBT) and midazolam clearance.” Submitted to Pharmacogenomics and Genetics. 14 pages.

6. Publications: Book Reviews

Paul W. Stewart


Review of "Time Series: A Biostatistical Introduction", Diggle PJ (Author); Stewart PW (Reviewer). JASA, 1992; 87: 255-255. Review of "Linear Mixed Models in Practice: A SAS-oriented Approach", Verbeke G and

Molenberghs G (Editors); Stewart PW (Reviewer). Technometrics, 1999; 41(1): 79-79. 7. Publications: Mongraphs Stewart PW (1990), "Classification Tree Prediction of Caries Using Clinical, Microbiological and

Interview Data," The 1990 Transactions of The Task Force on Design and Analysis: 49-63. Edited by Neal W. Chilton. Stewart PW (1977). “Some Properties of the Linear Prediction Estimator for the Power Spectrum of a Speech Wave: Original Results for Autoregressive Processes,” Master's Thesis, UNC-CH, Institute of Statistics Mimeo Series: 57 pages. The University of North Carolina, Chapel Hill, NC. Stewart PW, “The Thrill of Theory: Foundations for the Joy of Modeling”, Lecture notes for BIO263, Advanced Linear Models Theory: 485 pages. Available from UNC Custom Publishing. Stewart PW, “Matrix Results Useful in Statistics", Lecture notes for BIOS107 and BIOS108 one-hour review courses: 165 pages. Distributed by UNC Custom Publishing. Stewart PW, "The LINMOD GCMPACK User's Guide for Growth-Curve Model Analysis," Used in BIOS267 from 1979-1986: 12 pages. Stewart PW (2008) “What is a Pilot Study: GCRC Protocols Which Propose Pilot Studies”: 5 pages. www.cincinnatichildrens.org/research/divisions/c/ctrc/protocol/pilot-studies/

/Small_or_Pilot_Studies.htm { Cited in Connelly LM (2008) "Pilot Studies". Medsurg Nursing, 17: 411-412. } 8. Presentations 8.1 Statistical Presentations 2016 "Choosing a Sample Size and the Design and Purpose of Pilot Studies" UNC Dept of Anesthesiology, Chapel Hill, NC. May 11, 2016. 2015 "Biostatistics Seminar: Design and Purpose of Pilot Studies" NC TraCS Institute, Chapel Hill, NC. August 28, 2015. 2015 "Review of IRB Applications: Design and Analysis of Pilot Study Proposals " Seminar for IRB Staff Members, Chapel Hill, NC. June 24, 2015. 2014 "Speedy IRB Approval: Strategic Statistical Considerations in Preparation of IRB Applications " IRB Workshop for Investigators, Chapel Hill, NC. September 15, 2014.

Paul W. Stewart


2014 "Speedy IRB Approval: Strategic Statistical Considerations in Preparation of IRB Applications " IRB Workshop for Investigators, Chapel Hill, NC. March 28, 2014. 2014 "Pediatric Research Using Pilot Studies" Pediatric Pulmonology, UNC School of Medicine, Chapel Hill, NC. Sept. 5, 2014. 2013 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" Pediatric Pulmonology, UNC School of Medicine, Chapel Hill, NC. April 19, 2013. 2012 “Nonlinear Mixed-Effects Models for Ozone Exposure-Response” Joint Statistical Meetings (JSM), August 2012. 2012 “Nonlinear Models for Meta-Analysis of Summary Exposure-Response Data” Meeting of the IBS / ENAR. March 2012. 2011 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" UNC Clinical Research Scholars , UNC School of Medicine, Chapel Hill, NC. 2011 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" EPID 690, UNC School of Public Health, Chapel Hill, NC. January 27, 2011. 2010 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" UNC Clinical Research Scholars , UNC School of Medicine, Chapel Hill, NC. 2009 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" UNC Clinical Research Scholars , UNC School of Medicine, Chapel Hill, NC. 2008 “Directing Biostatistics Cores in Biomedical Research.” Invited session at the Joint Statistical Meetings, Denver, CO 2008 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" UNC Clinical Research Scholars , UNC School of Medicine, Chapel Hill, NC. 2007 "Pilot Studies, Feasibility Studies, and Small Exploratory Studies" UNC Clinical Research Scholars , UNC School of Medicine, Chapel Hill, NC. 2006 “A Bernoulli / Left-Censored Lognormal Mixture Model for Activity of the Protease of HIV-1 as a Function of Amino Acid Characteristics.” Invited presentation at the Joint Statistical Meetings, Seattle, WA. 2005 "Introduction to Power Analysis," UNC General Clinical Research Center (GCRC), Doris-Duke Research Fellows, UNC School of Medicine, Chapel Hill, NC. 2004 "Introduction to Power Analysis," UNC General Clinical Research Center (GCRC), Doris-Duke Research Fellows, UNC School of Medicine, Chapel Hill, NC. 2003 "Introduction to Power Analysis," UNC General Clinical Research Center (GCRC), Doris-Duke Research Fellows, UNC School of Medicine, Chapel Hill, NC.

Paul W. Stewart


2002 "Introduction to Power Analysis," UNC General Clinical Research (GCRC), UNC School of Medicine, Chapel Hill, NC. 1998 "Longitudinal Analysis of Menstrual Cycle Variation in Hormones, Lipids, Lipoproteins, and Hemostatic Factors in a Three-Period Crossover Study," Presented at March 1998 Meeting of the IBS / ENAR. 1995 "Risk Modeling of EPA Clinical Research Branch Ozone Response Data," EPA - UNC Cooperative Agreement Program, U.S. EPA, Chapel Hill, NC. 1995 "Longitudinal Analysis of Pulmonary Function for Cystic Fibrosis Patients," Biostatistics Dept., Genentech Inc., South San Francisco, CA. 1995 "Longitudinal Analysis of Long-term Benefits of Pulmozyme (R) for Cystic Fibrosis Patients,"

Biostatistics Dept., Genentech Inc., S. San Francisco, CA. 1993 "Simultaneous Confidence Bands for Nonlinear Longitudinal Models," Presented at August 1993 Joint Meeting of the ASA, IBS, and the IMS. 1993 "Simultaneous Confidence Bands for Non-Linear Longitudinal Models," Biostatistics Department, UNC, Chapel Hill, NC. 1992 "Methods for Tracking Analysis for Inconsistently Timed Longitudinal Data," Presented at August 1992 Joint Meeting of the ASA, IBS, and the IMS. 1991 "Analysis of Dose-Response Curves for Censored Repeated Measures," Presented at August 1991 Joint Meeting of the ASA, IBS, and IMS. 1991 "Tracking Analysis for Inconsistently Timed Longitudinal Data," Presented at June 1991 ASA Symposium on Longitudinal Data Analysis, 1991 "Methods for Informatively Right-Censored Longitudinal Data," Biostatistics Department, UNC, Chapel Hill, NC. 1991 "Methods for Right-Censored Longitudinal Data," Biostatistics Section, Bowman Gray School of Medicine, Winston-Salem, NC. 1991 "Tree-Structured Models for Classification and Regression," Biostatistics Department, UNC, Chapel Hill, NC. 1990 "Methods for the Analysis of Tracking in Inconsistently-Timed Longitudinal Data," Presented at Aug.'90 Joint Meeting of the ASA, Biometric Society, and the IMS. 1990 "Classification Tree Prediction of Caries Using Clinical, Microbiological and Interview Data," Presented to November 1990 Meeting of The Task Force on Design and Analysis for Dental Research. New Brunswick, NJ. 1990 "Classification Tree Prediction of Caries Using Clinical, Microbiological and Interview Data," Presented at Mar.'90 Meetings of the International Association of Dental Research. 1989 "The Graphical Advantages of Finite Interval Confidence Band Procedures,"

Paul W. Stewart


Presented at Aug.'89 Joint Meetings of the ASA, Biometric Society, and IMS. 1987 "Methods for Evaluation of Once-Repeated Measures for Evidence of Tracking," Presented at Aug.'87 joint Meetings of the ASA, Biometric Society, and IMS. 1987 "Finite Interval Confidence Bands for Repeated Measures," Mathematics Department, East Carolina University, Greenville, NC. 1985 "Finite Interval Confidence Bands for Repeated Measures," Biostatistics Department, Glaxo, Inc. 1985 "Finite Interval Confidence Bands for Repeated Measures," Biometrics Department, Medical University of South Carolina. 1985 "Finite Interval Confidence Bands for Repeated Measures," Statistics Department, University of Florida, Gainesville, FL. 1985 "Finite Interval Confidence Bands for Repeated Measures," Biostatistics Department, Vanderbilt University, TN. 1985 "Finite Interval Confidence Bands for Repeated Measures," Biostatistics Department, Emory University, Atlanta, GA. 1984 "Extension of the quantile estimator proposed by Harrell and Davis to finite populations," Presented at Mar.'85 Meetings of the International Biometric Society. 1979 "The Analysis of Growth and Dose-Response Curves," Presented at Aug.'79 Joint Meetings of the ASA, Biometric Society, and IMS. (Published in ASA Proceedings of Statistical Computation Section, 130-135.) 1979 "LINMOD Analysis of Growth and Dose-Response Curves," Presented at Aug.'79 The Conference of SAS Users Group International. (Published in Proceedings of the 4th Annual Conference of the SUGI, 266-271.) Award for Best Paper on Linear Models at this annual conference.

Paul W. Stewart


8.2 Statistical Presentation Collaborations (substantial contributions other than presentation) Köck K , Ferslew B, Netterberg I, Yang K, Urban TJ, Stewart PW, Brouwer KLR (2012) “Inhibition of

the hepatic basolateral bile acid transporter MRP4 predicts cholestatic drug-induced liver injury” 2012 AALSD Conference. McDonnell WF, Stewart PW, Smith M (2012) “Identification and Evaluation of a Dynamic Ozone-

FEV1 Exposure-Response Model for Use in Conducting Risk Assessment in Support of the NAAQS for Ozone.” Presentation to U.S. Environmental Protection Agency, Clean Air Scientific Advisory Committee (CASAC), Jan 9, 2012.

Edwards LJ, Muller KE, Gurka MJ, Stewart PW (2005) “ Selecting the Best Linear Mixed Model: The

State of the Art for Longitudinal Data Analysis.” Presented at the 2005 JSM. Stewart PW and DeMuth G (2002). “Estimation in Longitudinal Studies of Continuous Measures that are

Subject to Purposeful Censoring”. Presented at the March 2002 Meeting of the IBS / ENAR. Kilaru R, Stewart PW (2001) “Application of a Monte Carlo EM Algorithm to Left-Censored Bivariate Normal Data”. Presented at the March 2001 Meeting of the IBS / ENAR. Bowman D, Sen PK, Stewart PW (1999) “Statistical Methods for Obtaining Inferences about Projected Completors in Longitudinal Studies with Non-ignorable Dropout”. Presented at 1999 JSM. Cox T and Stewart PW (1997), "Evaluation of the Performance of Mixed-Model Procedures for

Ophthalmologic Data,"Presented at March 1997 Meeting of the IBS / ENAR. Cox T and Stewart PW (1997), "Evaluation of the Performance of GEE Procedures for Ophthalmologic

Data," Presented at March 1997 Meeting of the IBS / ENAR. Burchinal, MR., Stewart PW, Pekow, PS, Helms, RW. (1991), "Tracking in Inconsistently-Timed

Longitudinal Pulmonary Function Data: Empirical Results," Presented at the 1991 JSM. Helms RW, McCanless I, Christiansen DH, Hosking JD, Muller KE, Stewart PW (1979), "Using GLMM5 for general linear models analysis: A tutorial", Presented at 4th Annual SAS Users

Group International Conference. (Published in Proceedings of the SUGI Conference, pp 234- 271.) 8.2 Biomedical Presentation Collaborations (substantial contributions other than presentation) Stewart PW, Yankaskas J, Egan TM. (2014) The growing impact of lung transplant (LTX) on survival

for patients with cystic fibrosis (CF) (Abstract). The Journal of Heart and Lung Transplantation;33(4):S227-S8. Presented to the International Society for Heart and Lung Transplantation on 2014-04-11 in San Diego, California.

Egan T, Dong B, Blackwell J, Simmons W, Jernigan E, Nicotra W, Haithcock J, Haithcock B, Tian Z,

Reddy S, Birchard K, Stewart PW, Noone P. (2011) Ex-vivo lung perfusion (EVLP) of human lungs: a preclinical study to assess transplant suitability (Abstract). Chest. 2011;140(4)

(Meeting Abstracts; 841A):doi: 10.1378/chest.1117602.

Paul W. Stewart


Egan T, Haithcock B, Long J, Noone P, Blackwell J, Forrest L, Gazda S, Reddy S, Davis R, Birchard K, Stewart PW. Preliminary results of a Phase II trial comparing outcomes of patients transplanted with lungs from uncontrolled donation after cardiac death donors (uDCDDs) assessed with ex-vivo lung perfusion (EVLP) to lungs from conventional brain-dead donors (Abstract). The Journal of Heart and Lung Transplantation 14;33(4):S17. Presented to the International Society for Heart and Lung Transplantation on 2014-04-11 in San Diego, California.

Egan TM, Blackwell J, Forrest L, Gazda S, Requard JJ, Haithcock B, Birchard K, Stewart PW, Randell

S, Venkataraman A, Beamer S, Reddy S, Myers B, Bachman M, Casel N, Niedfeldt D. (2014) Evaluation of human lungs from uncontrolled donation after cardiac death donors (uDCDDs) with ex-vivo lung perfusion (EVLP) [Abstract]. The Journal of Heart and Lung Transplantation. 33(4):S47. Presented to the International Society for Heart and Lung Transplantation on 2014-04-11 in San Diego, California.

Egan TM, Dong B, Blackwell J, Birchard K, Stewart PW, Funkhouser W, et al. Assessing human lungs

unsuitable for transplant by ex-vivo lung perfusion (EVLP) and ex-vivo CT scan; Does EVLP cause inflammation? (Abstract) The Journal of Heart and Lung Transplantation 34 (4S):S139. Presented to the International Society for Heart and Lung Transplantation on 2014-04-11 in San Diego, California.

Egan TM, Gazda S, Stewart PW. If I had a million lungs: Impact of uncontrolled donation after cardiac

death donors (uDCDDs) on the number of potential lung donors in the U.S. (Abstract). The Journal of Heart and Lung Transplantation 33(4):S47. Presented to the International Society for Heart and Lung Transplantation on 2014-04-11 in San Diego, California.

McDonnell W, Stewart PW, Smith M (2008) “Modification of a Human Ozone Exposure-Response

Model and Evaluation of Its Performance in Predicting Mean Changes in FEV1 in Independent Data.” U. S. Environmental Protection Agency Workshop on Ozone, October, 2008.

Kipp AM, Stewart PW, Pungrassami P, Chongsuvivatwong V, van Rie A. (2008) “TB stigma

trajectory among patients completing TB treatment in Southern Thailand”. AIDS Conference, Mexico City, 2008.

Dow A, Mupuala A, Stewart PW, van Rie A. (2008) “The Effects of Provision of HIV care on

Neurodevelopment of Preschool children. AIDS Conference, Mexico City, 2008 Hoffman IF, Martinson FEA, Fiscus SA, Sohoni P, Komoltri C*, Chilangozi DA, Kazembe PN,

Stewart PW, and Cohen MS. (2007) “Factors Affecting the Detection of HIV-1 RNA in Breast Milk.” 14th Conference on Retrovirus and Opportunistic Infections (CROI), Los Angeles, CA, February 25-28, 2007.

Sigounas D, Stewart PW, Samer E, Bullitt E, Kilpatrick M, Ewend (2007) "A New Measurement

Criterion For Volumetric Evaluation Of Metastatic Brain Tumors”. Presented to the Society of Neuro-Oncology, Dallas, Texas, November 15-18, 2007.

Pilcher C, Tien H-C, Stewart PW, Vernazza P, Chakraborty H, Eron J Jr, Cohen M (2007). “Estimating

Transmission Probabilities over Time in Acute HIV Infection from Biological Data” 14th Conference on Retrovirus and Opportunistic Infections (CROI), Los Angeles, CA, Feb 25-28, 2007.

Dumond JB, Yeh RF, Patterson KB, Corbett AH, Jung BH, Rezk NL, Bridges AS, Stewart PW, Cohen

MS, Kashuba ADM (2007). Antiretroviral drug exposure in the female genital tract: implications for

Paul W. Stewart


oral pre- and post-exposure prophylaxis. 14th Conference on Retrovirus and Opportunistic Infections (CROI), Los Angeles, CA, February 25-28, 2007.

Fiscus SA, Cachafeiro A, Stewart PW, Napravnik S, Frank I, Eron J Jr, and the AACTG NWCS 227

Team (2007). “Cavidi Exavir Viral Load and Phenotype Assays” 14th Conference on Retrovirus and Opportunistic Infections (CROI), Los Angeles, CA, February 25-28, 2007.

Hoffman IF, Martinson FEA, Fiscus SA, Sohoni P, Komoltri C, Chilangozi DA, Kazembe PN,

Stewart PW, and Cohen MS. (2007) “Factors Affecting the Detection of HIV-1 RNA in Breast Milk.” 14th Conference on Retrovirus and Opportunistic Infections (CROI), Los Angeles, CA, February 25-28, 2007.

Fiscus SA, Cachafeiro A, Stewart PW, Napravnik S, Frank I, Eron J Jr, and the Adult ACTG NWCS

227 Team. (2006). Cavidi Exavir Viral Load and Phenotype Assays. Presented at the 13th Annual Conference on Retroviruses and Opportunistic Infections.

Pilcher C, Tien H-C, Stewart PW, Vernazza P, Chakraborty H, Eron JJ Jr, Cohen MS. (2006)

Estimating Transmission Probabilities over Time in Acute HIV Infection from Biological Data. Presented at the 13th Annual Conference on Retroviruses and Opportunistic Infections.

Hoffman I, Martinson FEA, Fiscus SA, Sohoni C, Komoltri C, Chilangozi DA, Kazembe PN,

Stewart PW, Cohen MS. (2006). Factors Affecting the Detection of HIV-1 RNA in Breast Milk. Presented at the 13th Annual Conference on Retroviruses and Opportunistic Infections.

Paine MF, Ludington SS, Chen ML, Stewart PW, Huang SM, Watkins PB (2005). Does sex influence

proximal small intestinal cyp3a or p-gp expression? Presented at the ASCPT meetings March, 2005. Paine MF, Ludington SS, Chen ML, Stewart PW, Huang SM, Watkins PB (2005). Does sex influence

proximal small intestinal cyp3a or p-gp expression? Presented at the FDA Science Forum, April 2005.

McDonnell WF, Stewart PW, Smith MV (2003). A Dynamic Nonlinear Model of Ozone-Induced

FEV1 Response Under Changing Exposure Conditions. Presented at the 99th Conference of the American Thoracic Society, Seattle, May 21, 2003.

Moe CL, Stewart PW, Savitz D, Koltai D, Loomis D, Hutton S, Bell P (2003). NC Study of Estuaries

and Rivers and Cohort Health (NC SEARCH): Preliminary Results. Presented to CDC, Wilmington, NC, October 31, 2003.

Stewart PW, Moe CL, Savitz D, Koltai D, Loomis D, Hutton S, Bell P (2003). NC Study of Estuaries

and Rivers and Cohort Health (NC SEARCH): Statistical Methods and Preliminary Results. Presented to CDC, Atlanta, GA, January 29, 2003.

Stewart PW, Moe CL, Savitz D, Koltai D, Loomis D, Hutton S, Bell P (2003). NC Study of Estuaries

and Rivers and Cohort Health (NC SEARCH): Illustrated Methods and Plans for Statistical Analysis of Study Data. Presented to CDC, Richmond, VA, April 16, 2003.

Pilcher CD, Tien HC, Stewart PW, Vernazza PL, Cohen MS. (2002) Estimating Transmission

Probabilities over Time in Acute HIV Infection from Biological Data. (CFAR-supported). Abstract

Paul W. Stewart


366-M. Presented at the 9th Conference on Retroviruses and Opportunistic Infections, Seattle, Feb 24-28, 2002.

Pilcher CD, Tien HC, Vernazza P, Stewart PW, Chakraborty H, Eron J, Cohen M (2002). Semen

Viral Dynamics In Acute HIV Infection: Implications for Sexual Transmission. (CFAR-supported). Abstract 367-M. Presented at XIV International Conference on AIDS

Lindesmith L, Moe CL, Stewart PW, Baric RS (2001) “Evidence of Protective Mucosal Immune

Response to NV Infection.” (Acknowledged Lauren Lindblad.) Presented at a symposium of the US EPA, RTP, NC. July 2001.

Jere CS, Hoffman I, Stewart PW, Kilaru R, Broadhead RL, Molyneux ME, Hart CA, Cunliffe NA,

and Fiscus SA. (2000) “HIV Viral Loads in HIV Infected Malawian infants Co-infected with Rotavirus.” (CFAR-supported.) XIII International AIDS Conference, Durban South Africa, July 2000.

Hoffman IF, Martinson FEA, Fiscus SA, Sohoni P, Komoltri C, Chilongozi DA, Kazembe PN,

Stewart PW, Cohen MS (2000) “Factors Affecting the Detection of HIV RNA in Breast Milk.” (CFAR-supported) XIII International AIDS Conference, Durban South Africa, July 2000.

Stephenson B, Wohl D, Kiziah N, et al. (2000) “Release from Prison is Associated with Increased HIV RNA at Time of Reincarceration”, XIII International AIDS Conference, Durban, South Africa, July 2000.(Acknowledgements to CFAR Bios Core support.) McDonnell WF with Stewart PW, Smith M, Pan W (2000) "Ambient Ozone: Development of

Exposure-Response Models for the Acute Respiratory Effects of Inhaled Irritants in Humans: Effects of Concentration, Minute Ventilation, and Duration” invited paper at U.S. EPA Symposium on

“Indictators of Health and Ecological Risk Assessment” June 2000, RTP, NC. Moe C, Stewart PW (2000), “Nonlinear Mixed-Effects Models for Norwalk Virus Dose Response” Presented at the W.H.O. Workshop on Hazard Characterization of Pathogens in Food and Water, June 2000, Bilthoven, Netherlands. McDonnell WF, Stewart PW (1999). “Exposure-response modeling of ozone-induced FEV1 changes in humans: Effects of concentration, duration, minute ventilation, & age.” Presented at Workshop on Quality Assurance of Environmental Models; Sponsored by National Center for Statistics and the Environment (NRCSE) and by the U.S.E.P.A.” Seattle, September 7-10, 1999. Davenport ML, Punyasavatsut N, Gunther D, Savendahl L, Stewart PW (1999) “Turner syndrome: a pattern of early growth failure.” Presented at Endocrinology Workshop sponsored by Pharmacia & UpJohn, Nice, France, April 15, 1999. Fiscus SA, Hoffman IF, Stewart PW, Kilaru R, Broadhead RL, Molyneux ME, Hart CA, and Cunliffe NA. (1999) HIV viral loads in HIV-infected Malawian infants co-infected with rotavirus. 2nd Conference on Global Strategies for the Prevention of HIV Transmission from Mothers to Infants, Montreal, Canada, September 1999. Kris-Etherton PM, Stewart PW, for the DELTA Investigators (1998), "Prediction Equations for Hemostatic Factors." Presented at April '98 Meeting of the Fed. of Am. Societies of Exper. Biology. (FASEB)

Paul W. Stewart


DuFort V, Kotch J, Stewart PW, Harb M, McMurray M (1998), “Are home-care children different from out-of-home care children?” Presented to the 4th World Conference on Injury Prevention & Control, Amsterdam. Moe C, Stewart PW, Harb M (1998), “Norwalk Virus Dose Response” Presented to the U.S. Environmental Protection Agency, RTP, NC. Davenport M, Punyasavatsut N, Stewart PW, (1998), “Growth in Infancy and Childhood in Turner’s Syndrome: New Growth Charts” Presented at the Endocrine Society Conference, June 1998. Kotch JB, Fieberg J, Brennan M, Dufort V, McMurray M, Stewart PW (1996), “Injuries Among Children In Home And Out-Of-Home Care” Presented at the National Head Start Research Conference, Washington, DC. McDonnell B, Stewart PW, Smith M, (1995), "Respiratory Response to Varying Levels of Ozone as a Function of Minute Ventilation Rate". Presented at May'95 Meetings of the American Thoracic Society. Abstract published in Proceedings of the ATS, (1995). Henry MM, Stewart PW, Henderson FW, (1994), "Longitudinal study of, allergy, wheezing illnesses, and lung function in a population of children in Raleigh, NC." Presented at May'94 Meetings of the American Thoracic Society. Margolis MQ, Hunt RJ, Vann WF, Stewart PW (1993), "Caries Risk Assessment in Primary Teeth of First Grade Children", (Masters' Thesis), Presented at Mar.'93 Meetings of International Association of Dental Research. Stamm JW, Stewart PW (1992). "Risk Factor Models for Caries Prediction." Presented at Jul.'92 International Conference on Oral Biology, Edinburgh, Scotland. Stamm JW, Disney JA, Beck JD, Weintraub JA, Stewart PW (1991), "Caries Risk Assessment for Children According to Prior Caries Experience." Presented at Jun.'91 Conference on Cariology For the Nineties, Rochester, NY. Weintraub JA, Kaste LM, Beck JD, Stewart PW, Abernathy J, Disney JA (1991), "Caries Risk Assessment for Children According to Prior Caries Experience." Presented at Jul.'91 Meetings of International Association of Dental Research, Stamm JW, Stewart PW, Bohannan HM, Disney JA, Graves RC, Abernathy JR (1990), "Risk Assessment for Oral Disease." Presented at Prevention Revisited: A Special Symposium, Seventy-Fifth Anniversary Celebration, Eastman Dental Center, Rochester, NY; Sep.'90. Scruggs RR, Stewart PW, Samuels MS, Stamm JW (1990), "Attitudinal assessment of students with curriculum changes." Presented at '89 Meeting of American Association of Dental Schools, New Orleans. Scruggs RR, Stewart PW, Samuels MS, Stamm JW, (1989), "Clinical evaluation of six anti-calculus dentifrice formulations." Presented at Mar.'89 Meetings of International Association of Dental Research. Piazza FM, Henry MM, Muelenaer AA, Ivins SS, Stewart PW, Henderson FW, Voter KZ,

Paul W. Stewart


Strope GL (1988), "Wheezing associated lower respiratory illness in early childhood and later lung function in non-asthmatic black children". Presented at May'88 Meetings of the American Thoracic Society. Muelenaer AA, Henry MM, Piazza FM, Ivins SS, Stewart PW, Henderson FW, Voter KZ, Strope GL (1988), "Bronchial responsiveness to isoetharine and methacholine in healthy, non-asthmatic black children". Presented at May'88 Meetings of the American Thoracic Society. 8.3 Presentations with Acknowledgement: the NIH DELTA Study (Dr. Stewart designed the analysis strategy and co-authored the abstracts, papers, & presentations.) Kris-Etherton PM, for the DELTA Investigators* (1996), "Cholesterol Lowering Diet Effects on Biologic Covariation Among Plasma Total Cholesterol, Triglyceride, & Factor VIIc Levels." Presented at Apr.'97 Meeting of the Fed. of Am. Societies of Exper. Biology. Dennis BH, for the DELTA Investigators* (1996), "Diet Design for Multicenter Studies of Diet and Lipoproteins in Humans." Presented at Nov.'96 Meeting of the American Heart Association. Berglund L, for the DELTA Investigators* (1996), "HDL Subclass Pattern During Reduction of Dietary Saturated Fatty Acids in Healthy Subjects." Presented at Nov.'96 Meeting of the American Heart Association. Ershow A, for the DELTA Investigators* (1996), "Dietary Effects on Lipoproteins and Thrombogenic Activity in Subjects with Markers for Insulin Resistance (DELTA2): Study Design and Recruitment." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Phillips K, for the DELTA Investigators* (1996), "Diet Composition Validation and Monitoring as Part of a Multicenter Clinical Feeding Trial of Step 1, High Mono-Unsaturated Fat, and Average American Diets." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Kris-Etherton PM, for the DELTA Investigators* (1996), "Effects of Replacing Saturated Fat (SFA) with Mono-Unsaturated Fat (MUFA) or Carbohydrate (CHO) on Plasma Lipids and Lipoproteins in Individuals with Markers for Insulin Resistance." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Elmer PT, for the DELTA Investigators* (1996), "Effects of a Step1 Diet and a High Mono-Unsaturated (MUFA) Fat Diet on Hemostatic Factors in Individuals with Markers for Insulin Resistance." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Lefevre M, for the DELTA Investigators* (1996), "Do ApoB & ApoA-IV Polymorphisms Affect Lipid Response to Reductions in Dietary Saturated Fat in Humans." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Ginsberg HN, for the DELTA Investigators* (1996), "Step1 Diet and a High Mono-Unsaturated Fat-Modified Step1 Diet Have Equal [or Similar] Effects on

Paul W. Stewart


Post-Prandial Lipids and Glucose Levels in Patients with Markers for Insulin Resistance." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Berglund L, for the DELTA Investigators* (1996), "Variation of HDL Subclass Pattern During Dietary Intervention in Subjects with Markers for Insulin Resistance." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Reed RG, for the DELTA Investigators* (1996), "Cyclic Variability of Plasma Lipids, Lipoproteins, and Thrombogenic Factors in Premenopausal Women." Presented at Apr.'96 Meeting of the Fed. of Am. Societies of Exper. Biology. Reed RG, for the DELTA Investigators* (1995), "Variance in Serum Lipids and Lipoproteins with Menstrual Cycle in Premenopausal Women." Presented at May'95 Meetings of the American Association for Clinical Chemistry. Abstract published in Clin. Chem. 41, S136 (1995). Reed RG, for the DELTA Investigators* (1995), "Variance in Lipids & Lipoproteins With Menstrual Cycle in Premenopausal Women Is No Greater Than Variance in Postmenopausal Women or Men". Presented at Mar.'95 Confer. on Cardiovascular Disease Epidemiology & Prevention. Abstract published in Circulation 91, 923 (1995). Reed RG, for the DELTA Investigators* (1995), "Dietary Fat in Women: Do Effects on Lipids Vary with Menstrual Status?" Presented at Apr.'95 Meetings of the Fed. of Am. Societies of Exper. Biology. Abstract published in the FASEB Journal 9, A290 (1995). Elmer PT, for the DELTA Investigators* (1995), "Dietary Effects on Lipoproteins & Thrombogenic Activity: Effects of Reducing Dietary Total & Saturated Fats on Hemostatic Factors" Presented at Apr.'95 Meeting of the Fed. of Am. Societies of Exper. Biology. Ginsberg HN, for the DELTA Investigators* (1995), "Diet Effects on Lipids & Thrombogenic Activity: Effects of Reducing Dietary Total & Saturated Fat on Plasma Lipids and Lipoproteins", Presented at Apr.'95 Meeting of the Fed. of Am. Societies of Exper. Biology. Lefevre M, for the DELTA Investigators* (1995), "Relationship Between ApoE Genotype and Lipid Response to Dietary Saturated Fat", Presented at Apr.'95 Meeting of the Fed. of Am. Societies of Exper. Biology. Ershow A, for the DELTA Investigators* (1995), "Dietary Effects on Lipoproteins and Thrombogenic Activity: Rationale and Design", Presented at Apr.'95 Meeting of the Fed. of Am. Societies of Exper. Biology. NIH / NCBI “MyBibliography” Complete List of Published Work in MyBibliography

http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40409685/?sort=date&direction=ascending

Paul W. Stewart


Teaching Experience Dr. Stewart maintains a teaching portfolio that is available upon request. It addresses the following

three components of his experience in teaching. 1. The Process – How, When, and Where One Teaches 2. The Content – Peer Review of What One Teaches 3. The Outcomes – The Effects of Teaching on the Student 1. Supervision and Training of Graduate Student Assistants Dr. Stewart's teaching experience has been in a variety of settings including the School of Public

Health. Most of his experience teaching students of biostatistics has occurred in the process of training and supervising the many students who have worked with him on collaborative biomedical research projects as “graduate research assistants” (GRAs).

He has supervised and trained more than 40 GRAs. This teaching opportunity has involved

thousands of hours of direct, practical training and instruction in statistical methods, research strategy, database management, statistical computing, consulting skills, and scientific writing.

Dr. Stewart has also supervised the required practical consulting experiences of 15 students in the

UNC Biostatistics Department. Dr. Stewart’s research projects involving GRAs usually result in co-authorships for both Dr. Stewart

and the GRA. In other cases, Dr. Stewart has provided oversight on “solo” collaborations of the GRA which resulted in publications such as this one for Dr. Tsui-Shan Lu while a graduate student:

Engmann C, Adanub R, Lu T-S, Bose C, Lozoff B (2008). Anemia and iron deficiencyin pregnant Ghanaian women from urban areas, International Journal of Gynecology and Obstetrics, 101(1):62-66. 2. Biostatistics Courses in the Classroom In the classroom Dr. Stewart has also provided approximately 355 student credit hours of instruction. (355 = credit hours per student number of students.) He taught BIOS 263 “Advanced Theory of

Linear Models” for ten semesters (1987-1997) and produced the following text book: Muller KE, Stewart PW (2006) Linear Model Theory: Univariate, Multivariate, and Mixed Models, Wiley Interscience, NY. 410 pages. He also taught BIOS 267, BIOS 107, BIOS 108, and guest lectures in other biostatistics courses. Dr. Stewart is currently teaching BIOS 841 “Principles of Statistical Consulting” with Dr.

Bangdiwala and Dr. Dominik. 3. Guest Lectures, Conference Presentations, Seminars In addition to conference presentations, Dr. Stewart has provided guest lectures, tutorials, and

seminars to groups and clients in the Schools of Medicine, Dentistry, Pharmacy, and Public Health and to other groups apart from the UNC system.

4. Teaching During Consultation and Collaboration with Biomedical Investigators

Paul W. Stewart


Last, but certainly not least, statistical consultation is rife with teaching opportunities. Consultation

with biomedical investigators involves clarification of fundamental statistical concepts, tutorial explications, and dissemination of methods innovations. Collaboration is a two-way learning (teaching) experience.

These face-to-face teaching opportunities are especially important for improving the quality of research

undertaken by investigators who are junior faculty. 5. Direction of Dissertation and Master’s Thesis Research Dr. Stewart has directed the thesis research of students of biostatistics and has served as an active

member of thesis committees. 5.1 Doctoral Research Directed Jamie Powers 2011, “ROC Generalized Linear Model Methods for Longitudinal Analysis of Psychiatric Pharmaceutical Clinical Trials” with Dr. John Preisser, in progress. (Quintiles, Inc.) Steven Enck 2009, “Latent Class Hierarchical Linear Models for Multivariate Longitudinal Data” (SAS Institute) George Demuth 2005-, “Purposeful Censoring in Longitudinal Study Designs” (CEO of StatTech Inc.) Dubois Bowman 2000, “Mixed Model Methods for Non-ignorably Missing Data". with Dr. P. K. Sen (Emory U., Biostatistics) Penny Pekow 1991, “The Analysis of Tracking in Longitudinal Data.” (U. Conn., Biostatistics) 5.2 Doctoral Research Committee Member Ashley Buchanan 2014, “Causal Inference in HIV/AIDS Research: Generalizability and Applications ” (Harvard U, Biostatistics) Annie-Green Howard 2012, “Missing Data in Non-parametric Tests of Correlated Data with One Covariate of Interest ” (UNC-CH, Biostatistics) Aaron M. Kipp 2009, “Social Stigma and the New Tuberculosis” (Vanderbilt U., Epidemiology)

Paul W. Stewart


Sean Simpson 2008, “General Linear Models with Generalized AR(1) Covariance Structure for Longitudinal and Spatial Data” (Wake Forest U., Biostatistics) Anita Abraham 2008, “Model Selection Methods in the Linear Mixed Model for Longitudinal Data “ (US FDA, Biostatistics) Hae-Young Kim 2007, “Operating characteristics of group testing algorithms for case identification in the presence of test error” (NERI, Biostatistics) Jean Orelien 2007, “Assessing Goodness-of-Fit in the Linear Mixed Model” (CEO of Scimetrika, Inc.) David Rosen 2007, “Factors Associated with Voluntary HIV Testing and Serostatus Among North Carolina State Prisoners” (UNC Epid. Dept. and UNC School of Med.) Matt Gurka 2004, “The Box-Cox Transformation in the General Linear Mixed Model for Longitudinal Data” (U. Virginia, Biostatistics) Michael Jiroutek 2002, “Exact Coverage & Sample Size of a Linear Model for an for an Internal Pilot Design (final oral exam 08/16/02) (Salix Pharmaceuticals, Inc.) Chris Coffee 2000, “Internal Pilot Study Design and Analysis” (U. Alabama, Birmingham, Biostatistics) Laura Helms 2000, “Multiple Imputation in Clinical Trials” (CEO of Rho, Inc.) Jim MacDougal 2000, "Non-Parametric Models for Multivariate Longitudinal Data" (new england pharmaceutical industry) Lynnette Keyes 1999, “Linear Mixed-Effects Models” (UNC, FPG Center Biostatistics) Diane Catellier 1998, “GLMM Methods of Missing Data". (UNC, Biostatistics) Solange Andreoni 1997, "Repeated Measurements on Diagnostic Variables in Multi-Visit Clinical Studies." (Universidade Federal de São Paulo) Jin-Whan Jung 1997,“Multivariate Methods for Measures of Association for Quantifying Variation Among Two or More Groups in

Paul W. Stewart


Longitudinal or Crossover Studies.” (SAS Institute) Szu-Yun Leu 1996, "Informative Censoring in Non-linear Models". (UC-SD, Biostatistics) John Preisser 1995, “Robust Multivariate Regression for Discrete and Continuous Outcomes." (UNC Biostatistics) Yi-Hsin Connie Yang 1996, "Interim Analysis for Continuous Repeated Measurements". (Statistics Director, KMU Hospital, Taiwan ) Cheryl A. Roe 1996, "ML Estimation and Testing in Small Samples for Repeated Covariate Linear Models with Missing Data." Deborah Glueck 1996,"Power Analysis for Designs with Fixed and Random Predictors." (U. Colorado, Denver, Biostatistics ) Bob Lyles 1996, "Statistical Methods for Environmental Exposure Data." (Emory U., Biostatistics) Suzy Eberling 1994, "Preschool Dental Treatment and the Risk of Future Caries." (Dentist and Epidemiologist with Bristol Bay Area

Health Corporation Dillingham, AK) Scott Hamilton 1994, "Partially Linear Nonparametric Smoothing." (CEO of Biometrics and Randomization Technologies) Glenn Davies 1994, "Survey Sampling Methods in Dental Research." Anne R. Meibohm 1993, “Analysis of Survival with Imputed Covariate Data." Emilia Sakurai 1993, "Simultaneous Nonparametric Tests for 2-Way Layouts" Fraser Smith 1993, "Mixed Model Analysis of Censored Normal Distributions." (US FDA, Biostatistics) James Grady 1993, "Structured Covariance Matrices for Incomplete Longitudinal Data." (U. Conn., Biostatistics) Claudine Legault 1991, “Comparison of Sequential Methods for Clinical Trials.” (Wake Forest U., Biostatistics) Susan Hillis 1991, “Effects of daycare on the children of Sincelejo, Colombia.” (Emory U., Epidemiology) Peg Burchinal 1986, “Comparison of growth curve models in application to

Paul W. Stewart


human developmental functions” (UNC, FPG Center, Biostatistics) Dalton Andrade 1985, “MLE and Likelihood Ratio Tests in the Multivariate Normal Distribution with Incomplete Data and Patterned Mean and Covariance Matrix” (Universidade Federal do Ceara , Brazil) 5.3 Master’s Research Directed Meichen Dong 2016, Masters Paper on “Randomized Clinical Trials Subject to Patients Switching Treatment Regimens at Baseline” (UNC Biostatistics Department) Jieni Xu 2015, “Power Analysis of Study Designs in Environmental Studies” Reader only. (UNC Biostatistics) Lauren Lindblad 2002, “Statistical Models for Longitudinal Analysis of Menstrual Cycle Variation in Hormones, Lipids, Lipoproteins, and

Hemostatic Factors in a Three-Diet Crossover Study” (Duke U., DCRI Biostatistics) Mike Despirito 2002, “Nonlinear Models Establishing Standard Growth Curve Charts for Girls with Turners Syndrome (StatTech Services) Rakhi Kilaru 2000, “Application of the EM Algorithm to Left Censored Bivariate Normal Data” (Duke U., DCRI Biostatistics) Michelle Harb 1999, "Comparison of Model-Based Analysis Methods in an Exposure-Response Study of Norwalk Virus Infection”. (Rho, Inc., Biostatistics ) Tonya Stancil 1996, "Pediatric Respiratory Illness History: Concordance Between Parental Report and Medical Chart Review". 5.4 Statistical Mentoring of Doris Duke Foundation Fellows in the UNC GCRC / CTRC (Selected third-year medical students nation-wide) 2001 Lisa Schweigler, Peter Farkas, Ray Givens 2002 Kelly Fogelman, Julie Dombrowski, Christie Kistler, Jackson Hamilton, Neeta Ventepalli 2003 Anup Parikh, Raval Mehul, Kate Lawrence, David Edwards, Medina Miguel

Paul W. Stewart


2004 Scott Cameron, Maren Show, Leeza Park, Scott Genshaft, Arun Aneja, Victor Lai, Sheela Agarwal, Kris Gunn 2005 Michelle McCrain, Luke Richey, Jonathan George, Margaret Kosnar, Erik Kouba, Michelle Kiser 2006 Dimitri Sigounas, Sara Schultz, Sara Peterson, Emmanuel Thomas, Brian Alder, Farhad Ardeshirpour, JaVar Mayatt-Jones, Jessica Wiser, Kamal Kolappa 2007 Jackie Dosal, Andrea Tsai, Anjana Lal, Ethan Munzinger, Michael Hudson, Niyati Mukherjee, Sarah Graboski, Than-Thu Tran 2008 Ahmed Zihini, Alan Woodruff, Chloe Hill, Ermias Abebe, Raj Kurpad

Paul W. Stewart


Contracts and Grants 1. Overview of Collaborative Research 2014-present Co-Investigator and Biostatistician. HCV-PRIORITIZE Multi-Center Multi-Arm Randomized Clinical Trial of Treatment Regimens for Hepatitis C Virus.* University of Florida and UNC-CH School of Medicine 2014-present Co-Investigator and Biostatistician. HCV-PROP_UP Multi-Center Observational and Studies of Patient-Reported Outcomes During Treatment for Hepatitis C Virus.* UNC-CH School of Medicine 2011-present Co-Investigator and Biostatistician. HCV-TARGET Multi-Center Registry and Studies of Treatments for Hepatitis C Virus.* UNC-CH School of Medicine and HCV-TARGET Consortium 2008-present Co-Investigator and Biostatistician. Biostatistics Core* of NC TraCS Institute and CTSA Initiative. UNC-CH Biostatistics Department and the UNC-CH School of Medicine 2009-2016 Co-Investigator and Biostatistician. Ex-vivo Perfusion and Ventilation of Lungs from Non-Heart-Beating Donors to Assess Transplant Suitability.* UNC School of Medicine and Duke University School of Medicine 2008-2014 Co-Investigator and Biostatistician. Study of CYP3A Activity Measures. UNC School of Pharmacy. 2007-2012 Co-Investigator and Biostatistician. Study of CYP2B6 Genotype and Phenotype UNC School of Pharmacy. 2011-2013 Co-Investigator and Biostatistician. Vital Signs in the Elderly: Predictive Value of Triage in the Emergency Dept UNC School of Medicine 2008-2012 Co-Investigator and Biostatistician. Randomized Clinical Trial of Cantharidin vs. Placebo for Treatment of Molluscum Contagiosum in Pediatric Practice. UNC School of Medicine (* provides support for graduate research assistants)

Paul W. Stewart


1997-2008 Director of GCRC Biostatistics Core and Mentor in K12/K30 Program, General Clinical Research Center (GCRC)* UNC School of Medicine. 1998-2008 Director of CFAR Biostatistics Core, UNC Center for AIDS Research (CFAR)* 1999-2011 Co-Investigator and Biostatistician, Adult Pulmonary Ozone Studies of Exposure-Response. US-EPA, RTP, NC. 2001-2008 Co-Investigator and Biostatistician, Study of Pulmonary Inflammation in Cystic Fibrosis, UNC Department Pediatrics. 1999-2008 Co-Investigator and Biostatistician, Intervention to Improve Patient Compliance* UNC CFAR 1996-2006 Co-Investigator and Biostatistician, Longitudinal NC SEARCH Project* A prospective cohort study of estuary-associated syndrome in NC. CDC, NC, and UNC Department of Epidemiology. 2001-2006 Co-Investigator and Biostatistician, Gender, Nicotine and Stress-Induced Analgesia, UNC Department of Psychiatry.

1998-2007 Co-Investigator and Biostatistician, Study of Choline as an Essential Dietary Nutrient, UNC Department of Nutrition. 2002-2003 Co-Investigator and Biostatistician, Study of Inflammatory Bowel Disease, UNC Department of Medicine. 2001-2003 Co-Investigator and Biostatistician, Cytomegalovirus in HIV Patients* CFAR and UNC School of Medicine. 2002-2003 Co-Investigator and Biostatistician, Modeling Acute HIV Dynamics* CFAR and UNC School of Medicine. 1996-2002 Co-Investigator and Biostatistician, US-EPA Norwalk Virus Study of Exposure-Response. UNC Departments of Biostatistics and Epidemiology. 1999-2003 Consulting Biostatistician, Center for Inflammatory Disease, UNC School of Dentistry. (* provides support for graduate research assistants)

Paul W. Stewart


2000-2003 Consulting Biostatistician, Department of Orthodontics, UNC School of Dentistry. 1996-2003 Principal Investigator, Coordinating Center of NHLBI DELTA Program. Randomized multicenter collaborative trials for effects of experimental isocaloric diets on lipids, lipoproteins, and hemostatic factors. UNC Biostatistics Department. 1992-1999 Principal Investigator, Adult Pulmonary Ozone Studies of Exposure-Response.* US-EPA air quality research funded via UNC Cooperative Agreement. UNC Departments of Epidemiology and Biostatistics. 1997-2000 Consulting Biostatistician, UNC Thurston Arthritis Research Center (TARC). * 1996-1998 Principle Investigator of subcontract, Penn. State Univ., Chocolate Manufacturers Association Study* UNC Biostatistics Department. 1997-1999 Principal Investigator, Coordinating Center for the ACTA Study in the TARC.* Randomized multicenter collaborative trial comparing Arthrotec and Acetaminophine in arthritis patients. (Searle, Inc.) 1990-1997 Investigator, The Long-Scan Study* A Longitudinal Study of Risk of Abuse / Neglect. UNC Department Maternal & Child Health. 1993-1997 Co-Principal Investigator, Longitudinal Study of Injuries Among Children During Daycare.* UNC Department of Maternal & Child Health. 1992-1997 Co-Investigator, Biometry Core of NHLBI Duke-UNC Sickle Cell Center.* UNC Department of Biostatistics. 1992-1996 Co-Principal Investigator, Coordinating Center of NHLBI DELTA Program.* UNC Department of Biostatistics. 1986-1995 Biostatistician, Dental Research Center, UNC Department of Dental Ecology. (* provides support for graduate research assistants)

Paul W. Stewart


1986-1993 Investigator, NIDR Caries Risk Assessment Study.* UNC Department of Dental Ecology. 1992-1994 Co-Principal Investigator, NHLBI-UNC Study of Pediatric Lung Function, Viral Illness, Allergy, Environmental Tobacco Smoke in African-American Girls. * UNC Frank Porter Graham Child Development Research Center. 1992-1993 Consulting Statistician, CSCC- NHLBI "Study of Left Ventricular Dysfunction" (SOLVD). * UNC Biostatistics Department. 1982-1991 Co-Investigator and Director of Biostatistics Unit, Biometry Core of the NHLBI-UNC Pediatric Pulmonary SCOR. * UNC Departments of Biostatistics Department and Pediatrics. 1982-1991 Co-Investigator on Multiple Projects, NHLBI-UNC Pediatric Pulmonary SCOR. * Longitudinal Studies of Lung Function and Respiratory Illness. UNC Departments of Biostatistics and Pediatrics. 1982-1982 Investigator on NHLBI Lipid Research Clinics (LRC) Program, Biostatistics Department, School of Public Health, The University of North Carolina, Chapel Hill. (* provides support for graduate research assistants)

Paul W. Stewart


3. Research Grants Project Title HCV-PRIORITIZE Description Multi-Center Multi-Arm Randomized Clinical Trial of Treatment Regimens for Hepatitis C Virus. Prin. Investigator David Nelson Role of PW Stewart Chief Biostatistician Graduate Assistants Amaanti Sridhar Funded 2016-present Funding Agency PCORI Award 25% effort for biostatistics collaboration Project Title HCV-PROP-UP Description Multi-Center Observational Study of Patient-Reported Outcomes Before,

During, and After Treatment for Hepatitis C Virus. Prin. Investigator Donna Evon Role of PW Stewart Chief Biostatistician Graduate Assistants Jipcy Amador Sulbaran Funded 2016-present Funding Agency PCORI Award 20% effort for biostatistics collaboration Project Title HCV-TARGET Description Multi-Center Registry and Studies of Treatments for Hepatitis C Virus. Prin. Investigator Michael Fried Role of PW Stewart Chief Biostatistician Graduate Assistants Tom Stewart Funded 2012-present Funding Agency Industry consortium Award 15% effort for biostatistics collaboration Project Title NC TraCS Biostatistics Core Description Clinical and Translational Science Award (CTSA). Prin. Investigator Michael Kosorok, UNC Biostatistics Dept. Role of PW Stewart Biostatistician for “Collaboration”, “Methods Research”, “Training” Graduate Assistants Ja-An Lin, Thomas Stewart, Meichen Dong, and others Funded 19 May 2008 Fun ding Agency NIH Award NIH and UNC support for CTSA Initiative Project Title More And Better Lungs: Ex-Vivo Perfusion of Lungs from Non-Heart-Beating Donors Description NIH GO Grant. Prin. Investigator Thomas Egan, UNC Department of Surgery Role of PW Stewart Co-Investigator and Biostatistician Graduate Assistants Thomas Stewart Funded 1 September 2013 30 June 2016 Funding Agency NIH-NHLBI Award 20% effort for biostatistical collaboration Project Title Ex vivo Perfusion/Ventilation of Lungs to Assess Transplant Suitability

Paul W. Stewart


Description NIH GO Grant. Prin. Investigator Thomas Egan, UNC Department of Surgery Role of PW Stewart Co-Investigator and Biostatistician Graduate Assistants Ja-An Lin Funded 1 January 2010 31 December 2012 Funding Agency NIH-NHLBI Award 20% effort for biostatistical collaboration Project Title Evaluation of a Simulation-Based Cardiac Surgery Curriculum Description Evaluation of a simulation-based training curriculum in cardiac surgery Prin. Investigator Richard Feins Role of PW Stewart Co-Investigator and Biostatistician Graduate Assistants Amaanti Sridhar Funded 2015-2016 Funding Agency AHRQ Award 65% effort for biostatistics collaboration Project Title Human Cytochrome P450 4F Enzymes and Drug Interactions Description NIH R01 Prin. Investigator Michael Wang Role of PW Stewart Co-investigator and Biostatistician Graduate Assistants none Funded 6 September 2010 – 30 June 2015 Funding Agency NIH Project Title CFAR Biostatistics Core Description NIH Center for AIDS Research: Core F. Prin. Investigator PW Stewart, UNC Biostatistics Dept. Role of PW Stewart Chief statistician, Director. Other Co-Investigators Francoise Seillier-Moiseiwitsch Graduate Assistants Chula Komoltri, Rakhi

Paul W. Stewart - UNC Gillings School of Global Public...

Documents

Transcript of Paul W. Stewart - UNC Gillings School of Global Public...