Patologia Renal Case 1 - Sociedad Española de Anatomía ... · Patologia Renal Case 1 A....
Transcript of Patologia Renal Case 1 - Sociedad Española de Anatomía ... · Patologia Renal Case 1 A....
Case Renal Cancer
• Female 47 y
• Back pain
• CT: Large Renal Tumor (RK)
• Treatment: Radical surgery
• Treatment with everolimus and disease progression
– Multiple Lung metastases
– Multiple retroperitoneal metastases
Patología Molecular
• FISH HER-2: Amplificado • Oncocarta (Sequenon): • Somatic mutation profile obtained with iPlex
Single Base Extension and MassARRAY Detection (Sequenom)
• OncoCarta and CLIA panels Sample has been analyzed with two assay panels, OncoCarta and CLIA (see below list of assays included).
• Sample M13-00008: Positive for KRAS G12D mutation. Negative for mutations in remaining assays contained in the panels.
Patologia Molecular
FISH HER-2 Amplificado Trastuzumab
Oncocarta
Positive for KRAS G12D mutation
Negative for mutations in remaining assays
contained in the panels