Best Practices, LLC Strategic Benchmarking Research

Medical Affairs’ Role in Health Economics & Outcomes

Research within Oncology

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Table of Contents

Executive Summary pp. 3-9

Research Objectives & Methodology pp. 3

Participating Companies pp. 4

Abbreviations pp. 5-6

Key Findings & Insights pp. 7-9

Longevity of HO Groups pp. 10-11

HO Leadership pp. 12-13

HO Reporting Structure pp. 14-15

HO Group Staffing pp. 16-19

MA’s Role in HO Activities pp. 20-23

MA’s Role in Collecting HO Data pp. 24-25

Utilization of HO Data pp. 26-32

Impact of HO Data on Decisions pp. 33-36

About Best Practices, LLC pp. 37-38

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Field Research & Insight Development:

Ten survey responses from Medical Affairs leaders at top life-

science companies within mature markets

Analysis is focused on companies with oncology therapies

Additional deep-dive interviews with 5 selected Medical

Affairs executives- 2 VPs, 2 Directors and 1 Manager.

Provide Leading Insights on:

• Identify involvement level of

MA groups in HO activities

• Define opportunity fronts and

strategies to increase MA’s

role in HO data generation

and utilization

Research Objectives & Methodology

Research Objectives:

Illustrate how Medical Affairs (MA) is involved in Health Outcomes (HO) data generation and utilization

Highlight strategies for effective HO data communication and utilization

Understand challenges about MA’s involvement in HO activities

Identify industry drivers regarding HO groups

Define resource levels for HO groups

Business Objective:

This research delivers current data, and best practices from Medical Affairs leaders with an oncology focus at top

biopharmaceutical companies. The data will help companies focused on oncology therapies find better ways to develop

successful Health Outcomes groups.

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Universe of Learning: Research Participants from 2014-2015 Study

This study engaged 10 executives from leading life sciences companies. The analysis is focused on companies with oncology

therapies.

Benchmark Class

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Large Companies Segment

Segments and Abbreviations

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Abbreviations:

• MA: Medical Affairs

• HO: Health Outcomes

• HEOR: Health Economics Outcomes Research

• TA: Therapeutic Areas

• TBC: Total Benchmark Class

• TL: Thought Leader

• TLM: Thought Leader Management

Key Findings & Insights: Medical Affairs’ Role in Health Outcomes Research

Longevity of HO Groups: HO programs are common, but they represent a young initiative for many of

the benchmark class; sixty percent of companies have had it in place for less than three years.

Reporting Structure: Sixty percent of companies’ HO groups report to Medical Affairs. A majority of the

interviewed executives think that HO groups must report to a science and research oriented department

such as clinical or medical affairs. Between these two, medical affairs provides better opportunities for

needs assessment, communicating HO data insights, and interacting with key decision makers.

Medical Affairs’ Involvement in HO Activities: Medical Affairs is heavily involved in the clinical and

scientific research aspects of health outcomes activities. Over 70% of the Medical Affairs groups lead in

presenting pharma-economic data and developing clinical protocols for outcomes research .

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Majority of Participants Have Had a HO Program for More Than Four Years

A majority of the participants have had a HO program in place for more than four years. However, 40% either don’t have a HO

program in place or their HO program is less than a year old.

N=10

Longevity of Health Outcomes Group(s): How long has the HO program been in place at your company?

% Respondents

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No formal health outcomes group, 10%

More than 5 years, 40%

4-5 years, 0%

1-3 years, 20%

Less than a year, 30%

Length of HO Program

+

A Quarter of Participants Don’t Use Traditional Reporting Structure

Sixty percent of the HO groups report to Medical Affairs within the benchmark class. Since HO is a recent trend, some

companies still haven’t clarified the reporting structure for these groups.

Reporting Structure: To whom does the Health Outcomes group(s) report?

% Respondents

8

N=10

Other: International Marketing and Medical Affairs

Other, 20%

Sales & mrktg , 0%

Clinical developme

nt, 20%

Medical affairs,

60%

HO's Reporting Groups

Deliver presentations/

speeches

Identify and build

relationships with outcomes-

focused KOLs

Gather relevant customer

feedback & report back to

appropriate colleagues

Engage with key medical,

outcomes and commercial colleagues

Present pharmaco-

economic data or HEOR analysis

HO Groups Have Multi-Dimensional Field-Based Responsibilities

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Core Field-Based HO Responsibilities

Field-Based HO

Responsibilities

Field-based health outcomes employees serve as a scientific bridge between companies and health care system decision

makers in managed care. The field-based team provides scientific, medical, and pharmaco-economic support to customers.

They also bring back feedback that can improve products.

MA Has a Weak Involvement in the Commercial Aspect of HO Activities

The most frequently lead activity by MA groups is presenting pharmaco-economic data, which is lead by 78%.

Training speakers on the outcomes data is the least often conducted activity within MA groups.

N= 8 - 9

Health Outcomes Activities: Please indicate the level of your Medical Affairs organization’s involvement

in each of the following activities.

% Respondents

10

78%

71%

56%

50%

44%

38%

38%

33%

13%

29%

44%

38%

56%

63%

25%

67%

75%

57%

11%

13%

14%

11%

38%

13%

29%

Presenting pharmaco-economic data

Developing clinical protocols for outcomes research

Delivering scientific presentations / speeches

Training commercial teams on outcomes data

Identifying payers and building relationships

Identifying providers and building relationshps

Training speakers on outcomes data

Formulary discussions with payers

Developing product labels

Developing commercial collaterals on outcomes

Medical Affair’s Involvement in HO Activities

Lead Support Plan to Participate in the Next 12 Months None

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Burden of Illness is the HO Data that Resonates Across Stakeholders

Health Outcomes

Data

Patients

Providers Payers

• Quality of Life

• Burden of Illness

• Analysis of Efficacy

• Analysis of Efficacy

• Analysis of Safety

• Burden of Illness

• Burden of Illness

• Cost Analysis

• Economic Analysis

DISEASE

MANAGEMENT

ECONOMIC

OUTCOMES &

COST REDUCTION

IMPACT ON

DAY-TO-DAY LIFE

Patients, Payers and Providers are interested in: Impact on daily life, Economic outcomes & Cost reduction, and Disease

management.

HO Data and Different Stakeholders

About Best Practices, LLC

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Best Practices®, LLC is an internationally recognized thought leader in the field of best practice

benchmarking®. We are a research, consulting, benchmark database, publishing and advisory firm that

conducts work based on the simple yet profound principle that organizations can chart a course to superior

economic performance by leveraging the best business practices, operating tactics and winning strategies of

world-class companies.

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Chapel Hill, NC 27517

(Phone): 919-403-0251

www.best-in-class.com

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