NEW PREPARATIONS

1
950 the ointment has melted and reached every part of the nasal cavity. This treatment he has found to cut short an attack of whooping-cough and to do away almost entirely with the violent paroxysms of cough. NEW PREPARATIONS. ABRODIL (Bayer Products, Ltd., HI, St. Dunstan’s- hill, London, E.C.) has already been described in the columns of THE LANCET in reviewing a paper on excretion urography by Drs. H. Bronner and J. Schueller, of Cologne. It is the sodium salt of mono- iodo-methane-sulphonic acid. After intravenous injec- tion of large doses no inorganic iodine is found in the urine of rats, cats, and dogs, and this shows that it is excreted by the kidneys without the splitting off of iodine. It is also strongly diuretic. The diuresis is mainly in the first half hour, and the best pictures for the purposes of pyelography are therefore obtained during that period, the ideal time being usually 15 to 20 minutes after injection. Drs. Bronner and Schueller have tested abrodil as a medium for retrograde pyelography, and recommend for this purpose a 15 to 20 per cent. solution. The fact that abrodil is compatible with oxycyanide of mercury allows of its being used in conjunction with this antiseptic. The danger of sepsis is thereby diminished, and the surgeon is relieved of one of the anxieties uppermost in his mind when undertaking retrograde pyelography. SOMNOSAL (Messrs. H. R. Napp, Ltd., 3 and 4, Clement’s-inn, London, W.C.) is a combination of a brom-iso-valerianyl urea (grs. 5) with dimethyl- amido-phenyldimethyl-iso-pyrazolon (grs. 2-5). The preparation dissolves in alcohol and the usual solvents but is only partly soluble in water. It is put on the market as a trustworthy sedative of negligible toxicity, whose employment is unaccompanied by secondary symptoms or habit forming. A considerable amount of medical evidence is adduced of the utility of the preparation, which is free from barbiturates and opiates. From the same firm we have received a sample of ANOTAL, a combination of phenyl-cinchoninic acid and ethyl-urethane. The manufacturers claim satis- factory results for the new preparation in the treat- ment of rheumatism, gout, and local inflammations, the analgesic action being rapid, while medical evidence is adduced that it is well tolerated by patients who suffer from no gastric disturbance or cardiac depression if the suggested dosage is observed. Anotal is put up in phials of 30 tablets, and in bottles of 300, the dosage being one or two tablets, to be taken in cold water thrice daily, according to medical direction. Medical Diary Information to be included in this column should reach us in proper form on Tuesday, and cannot appear if it reaches us later than the first post on Wednesday morning. SOCIETIES. ROYAL SOCIETY OF MEDICINE, 1, Wimpole-street, W. MONDAY, April 27th.-8 P.M., ODONTOLOGY. Paper. Mr. Wilson Charles : Full Denture Prosthesis. 5 P.M., MEDICINE. Short Papers : Dr. W. S. C. Copeman : Treatment of Chronic Arthritis by Blood Transfusion. Dr. Donald Hall: Two Unusual Electrocardiograms. Dr. Donald Hunter: HEematog’enous Myelomatosis. Dr. M. Schwartzman : Skeletal Muscular Extract in the Treatment of Vascular Diseases. Dr. D. C. Wilson : Osteomalacia with Cinematographic film. FRIDAY, May 1st.-10.30 A.M., OTOLOGY (Cases at 9.30 A.M.). Annual General Meeting. Papers. Dr. Schmaltz (Germany): The Physical Phenomena Occurring in the Semicircular Canals during Rotatory and Thermic Stimulation. Dr. H. W. Barber : Eruptions Involving the External Auditory Meatus. Discussion: Non-malig- nant Diseases of the External Ear and Auditory Meatus. Cases and specimens will be shown. 5 P.M., LARYNGOLOGY (Cases at -t P.M.). Annual General Meeting. Communication. Prof. Georges Portrnann : A Big Tumour of the Deep Regions of the Face removed by Operation with Cure. Discussion : Obstruction at the Upper End of the (Esophagus (excluding Pharyn- geal Diverticula). Openers : Dr. A. Brown Kelly and Dr. D. R. Paterson. 8.30 P.M., ANÆSTHETICS. Annual General Meeting’. Election of Officers and Council. A Clinical Evening will follow. EUGENICS SOCIETY. TUESDAY, April 28th.-5.30 P.M. (at the Rooms of the Linnean Society, Burlington House, London, W.), Dr. A. J. Lewis : Genetic Problems in Psychiatry. WEST LONDON MEDICO-CHIRURGICAL SOCIETY. FRIDAY, May 1st.—8.30 P.M. (at West London Hospital Hammersmith): Discussion on Cholecystitis. (Opener, Dr. Maurice Shaw.) LECTURES, ADDRESSES. DEMONSTRATIONS, &c. FELLOWSHIP OF MEDICINE AND POST-GRADUATE MEDICAL ASSOCIATION, 1, Wimpole-street, W. MONDAY, April 27th, to SATURDAY, May 2nd.—HOSPITAL FOR SICK CHILDREN, Great Ormond-street, W.C. I Special post-graduate course in Diseases of Children, , occupying mornings only with lectures, demonstrations, and operations.—INFANTS HOSPITAL, Vincent-square, S.W.-Special afternoon course in diseases of infants. Demonstrations, lectures, and special visits.-MAUDSLEY HOSPITAL, Denmark-hill, S.E. An afternoon course of lectures in Psychological Medicine. Clinical instruc- tion in the Hospital.—CENTRAL LONDON THROAT, NosE, AND EAR HOSPITAL, Gray’s Inn-road, W.C. All-day Course in Diseases of the Ear, Nose, and Throat, lectures, demonstrations, &c.-Further particulars from the Fellowship of Medicine. UNIVERSITY COLLEGE HOSPITAL MEDICAL SCHOOL, University-street, Gower-street, W.C. WEDNESDAY, April 29th, and the following THURSDAY and FRIDAY.-5.30 P.M., Prof. Otfrid Forster (Univ. of Breslau) : Neurology. LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE, Keppel-street, Gower-street, W.C. TUESDAY, April 28th, and following WEDNESDAY, THURSDAY, and FRIDAY.-5 P.M., Prof. F. A. E. Crew : Laws of Inheritance. HAMPSTEAD GENERAL AND NORTH-WEST LONDON HOSPITAL. WEDNESDAY, April 29th.-4 P.M., Dr. Hubert Oddy : Treatment of Gastric Ulcer. MANCHESTER ROYAL INFIRMARY POST-GRADUATE COURSE. TUESDAY, April 28th.-4.15 P.M., Mr. J. P. Buckley: Some Problems of Early Diagnosis. FRIDAY, May 1st.—4.15 P.M., Mr. P. R. Wrigley : Demorstra- tion of Surgical Cases. MANCHESTER VICTORIA MEMORIAL JEWISH HOE’. PITAL, Elizabeth-street. Manchester. WEDNESDAY, April 29th.-4.30 P.M., Dr. W. Brockbank : The Medical Treatment of Asthma. UNIVERSITY OF BIRMINGHAM. TUESDAY, April 28th.-3.30 P.M. (at the General. Hospital), Mr. S. Barling : Demonstration of Surgical Cases. Births, Marriages, and Deaths Medical Diary BIRTHS. DE BARGUE HUBERT.—On April 18th, at Grosvenor-road, S.W., the wife of Dr. W. de Bargue Hubert, of a daughter. . MARRIAGES. AITKEN—WEST.—On April 14th, at Macduff, Banffshire, Alan Boultbee Aitken, of Creigiau, Cardiff, to Dr. Gladys Mary West. FAIRLEY—ROSSER.—On April 17th, at Saint Augustine’s-road, Edgbaston, James Fairley, B.Ch. Camb., to Margaret C. Rosser, M.B., Ch.B. HOBBES—CAMERON.—On April 16th, at St. Mary’s, Selly Oak, Theodore H. Hobbes, M.B., B.S., to Janet Seaton Cameron, M.B., Ch.B. DEATHS. ACLAND.—On April 16th, at Bryanston-square, London, W., Theodore Dyke Acland, M.D. Oxf., F.R.C.P., aged 79. CHRISTIE.—On April l4th, 1931, at 1, Albyn-terrace, Aberdeen, John F. Christie, M.A., M.B., C.M., F.R.C.P.E. DEAN.—On April 14th, at Abinger-road, Bedford Park, Henry Percy Dean, F.R.C.S., M.S., M.B., B.Se., aged 66. HARRIS.—On April 16th, Major-General G. F. A. Harris, C.S.I., M.D.. F.R.C.P., I.M.S., in his 76th year. SMITH.—On April 18th, at Cobden-crescent, Edinburgh, James Lorrain Smith, F.R.S., Professor of Pathology, University of Edinburgh. N.B.—A fee of 7s. 6d. is charged for the insertion of Notices oj Births, Marriages, and Deaths. HARROW HOSPITAL.—Last year each in-patient cost an average of,c3 5s. 9d. per week, as against £2 12s. in the preceding year. The average total costs of each patient- j67 10s.-includes 844 out-patients. The hospital was closed for six weeks last summer for alterations necessitated by the extension schemes.

Transcript of NEW PREPARATIONS

Page 1: NEW PREPARATIONS

950

the ointment has melted and reached every part ofthe nasal cavity. This treatment he has found tocut short an attack of whooping-cough and to doaway almost entirely with the violent paroxysms ofcough.

NEW PREPARATIONS.

ABRODIL (Bayer Products, Ltd., HI, St. Dunstan’s-hill, London, E.C.) has already been described inthe columns of THE LANCET in reviewing a paper onexcretion urography by Drs. H. Bronner and J.Schueller, of Cologne. It is the sodium salt of mono-iodo-methane-sulphonic acid. After intravenous injec-tion of large doses no inorganic iodine is found in theurine of rats, cats, and dogs, and this shows that it isexcreted by the kidneys without the splitting off ofiodine. It is also strongly diuretic. The diuresis ismainly in the first half hour, and the best picturesfor the purposes of pyelography are therefore obtainedduring that period, the ideal time being usually 15to 20 minutes after injection. Drs. Bronner andSchueller have tested abrodil as a medium for

retrograde pyelography, and recommend for this

purpose a 15 to 20 per cent. solution. The fact thatabrodil is compatible with oxycyanide of mercuryallows of its being used in conjunction with thisantiseptic. The danger of sepsis is thereby diminished,and the surgeon is relieved of one of the anxietiesuppermost in his mind when undertaking retrogradepyelography.SOMNOSAL (Messrs. H. R. Napp, Ltd., 3 and 4,

Clement’s-inn, London, W.C.) is a combination of abrom-iso-valerianyl urea (grs. 5) with dimethyl-amido-phenyldimethyl-iso-pyrazolon (grs. 2-5). Thepreparation dissolves in alcohol and the usual solventsbut is only partly soluble in water. It is put on themarket as a trustworthy sedative of negligibletoxicity, whose employment is unaccompanied bysecondary symptoms or habit forming. A considerableamount of medical evidence is adduced of the utilityof the preparation, which is free from barbituratesand opiates.From the same firm we have received a sample

of ANOTAL, a combination of phenyl-cinchoninic acidand ethyl-urethane. The manufacturers claim satis-factory results for the new preparation in the treat-ment of rheumatism, gout, and local inflammations,the analgesic action being rapid, while medicalevidence is adduced that it is well tolerated bypatients who suffer from no gastric disturbance orcardiac depression if the suggested dosage is observed.Anotal is put up in phials of 30 tablets, and in bottlesof 300, the dosage being one or two tablets, to betaken in cold water thrice daily, according to medicaldirection.

Medical DiaryInformation to be included in this column should reach us

in proper form on Tuesday, and cannot appear if it reachesus later than the first post on Wednesday morning.

SOCIETIES.ROYAL SOCIETY OF MEDICINE, 1, Wimpole-street, W.

MONDAY, April 27th.-8 P.M., ODONTOLOGY. Paper. Mr.Wilson Charles : Full Denture Prosthesis. 5 P.M.,MEDICINE. Short Papers : Dr. W. S. C. Copeman :Treatment of Chronic Arthritis by Blood Transfusion.Dr. Donald Hall: Two Unusual Electrocardiograms.Dr. Donald Hunter: HEematog’enous Myelomatosis.Dr. M. Schwartzman : Skeletal Muscular Extract inthe Treatment of Vascular Diseases. Dr. D. C.Wilson : Osteomalacia with Cinematographic film.

FRIDAY, May 1st.-10.30 A.M., OTOLOGY (Cases at 9.30 A.M.).Annual General Meeting. Papers. Dr. Schmaltz(Germany): The Physical Phenomena Occurring in theSemicircular Canals during Rotatory and ThermicStimulation. Dr. H. W. Barber : Eruptions Involvingthe External Auditory Meatus. Discussion: Non-malig-nant Diseases of the External Ear and AuditoryMeatus. Cases and specimens will be shown. 5 P.M.,LARYNGOLOGY (Cases at -t P.M.). Annual GeneralMeeting. Communication. Prof. Georges Portrnann :A Big Tumour of the Deep Regions of the Face removedby Operation with Cure. Discussion : Obstruction at

the Upper End of the (Esophagus (excluding Pharyn-geal Diverticula). Openers : Dr. A. Brown Kellyand Dr. D. R. Paterson. 8.30 P.M., ANÆSTHETICS.Annual General Meeting’. Election of Officers andCouncil. A Clinical Evening will follow.

EUGENICS SOCIETY.TUESDAY, April 28th.-5.30 P.M. (at the Rooms of the

Linnean Society, Burlington House, London, W.),Dr. A. J. Lewis : Genetic Problems in Psychiatry.

WEST LONDON MEDICO-CHIRURGICAL SOCIETY.FRIDAY, May 1st.—8.30 P.M. (at West London Hospital

Hammersmith): Discussion on Cholecystitis. (Opener,Dr. Maurice Shaw.)

LECTURES, ADDRESSES. DEMONSTRATIONS, &c.FELLOWSHIP OF MEDICINE AND POST-GRADUATEMEDICAL ASSOCIATION, 1, Wimpole-street, W.MONDAY, April 27th, to SATURDAY, May 2nd.—HOSPITAL

FOR SICK CHILDREN, Great Ormond-street, W.C.I Special post-graduate course in Diseases of Children,, occupying mornings only with lectures, demonstrations,

and operations.—INFANTS HOSPITAL, Vincent-square,S.W.-Special afternoon course in diseases of infants.Demonstrations, lectures, and special visits.-MAUDSLEYHOSPITAL, Denmark-hill, S.E. An afternoon courseof lectures in Psychological Medicine. Clinical instruc-tion in the Hospital.—CENTRAL LONDON THROAT,NosE, AND EAR HOSPITAL, Gray’s Inn-road, W.C.All-day Course in Diseases of the Ear, Nose, and Throat,lectures, demonstrations, &c.-Further particulars fromthe Fellowship of Medicine.

UNIVERSITY COLLEGE HOSPITAL MEDICAL SCHOOL,University-street, Gower-street, W.C.WEDNESDAY, April 29th, and the following THURSDAY and

FRIDAY.-5.30 P.M., Prof. Otfrid Forster (Univ. ofBreslau) : Neurology.

LONDON SCHOOL OF HYGIENE AND TROPICALMEDICINE, Keppel-street, Gower-street, W.C.TUESDAY, April 28th, and following WEDNESDAY, THURSDAY,

and FRIDAY.-5 P.M., Prof. F. A. E. Crew : Laws ofInheritance.

HAMPSTEAD GENERAL AND NORTH-WEST LONDONHOSPITAL.WEDNESDAY, April 29th.-4 P.M., Dr. Hubert Oddy :

Treatment of Gastric Ulcer.MANCHESTER ROYAL INFIRMARY POST-GRADUATECOURSE.TUESDAY, April 28th.-4.15 P.M., Mr. J. P. Buckley:

Some Problems of Early Diagnosis.FRIDAY, May 1st.—4.15 P.M., Mr. P. R. Wrigley : Demorstra-

tion of Surgical Cases.MANCHESTER VICTORIA MEMORIAL JEWISH HOE’.PITAL, Elizabeth-street. Manchester.WEDNESDAY, April 29th.-4.30 P.M., Dr. W. Brockbank :

The Medical Treatment of Asthma.UNIVERSITY OF BIRMINGHAM.

TUESDAY, April 28th.-3.30 P.M. (at the General.Hospital), Mr. S. Barling : Demonstration of SurgicalCases.

Births, Marriages, and Deaths

Medical Diary

BIRTHS.DE BARGUE HUBERT.—On April 18th, at Grosvenor-road, S.W.,

the wife of Dr. W. de Bargue Hubert, of a daughter.

. MARRIAGES.

AITKEN—WEST.—On April 14th, at Macduff, Banffshire, AlanBoultbee Aitken, of Creigiau, Cardiff, to Dr. Gladys MaryWest.

FAIRLEY—ROSSER.—On April 17th, at Saint Augustine’s-road,Edgbaston, James Fairley, B.Ch. Camb., to Margaret C.Rosser, M.B., Ch.B.

HOBBES—CAMERON.—On April 16th, at St. Mary’s, Selly Oak,Theodore H. Hobbes, M.B., B.S., to Janet Seaton Cameron,M.B., Ch.B.

DEATHS.ACLAND.—On April 16th, at Bryanston-square, London,

W., Theodore Dyke Acland, M.D. Oxf., F.R.C.P., aged 79.CHRISTIE.—On April l4th, 1931, at 1, Albyn-terrace, Aberdeen,

John F. Christie, M.A., M.B., C.M., F.R.C.P.E.DEAN.—On April 14th, at Abinger-road, Bedford Park, Henry

Percy Dean, F.R.C.S., M.S., M.B., B.Se., aged 66.HARRIS.—On April 16th, Major-General G. F. A. Harris,

C.S.I., M.D.. F.R.C.P., I.M.S., in his 76th year.SMITH.—On April 18th, at Cobden-crescent, Edinburgh, James

Lorrain Smith, F.R.S., Professor of Pathology, Universityof Edinburgh.

N.B.—A fee of 7s. 6d. is charged for the insertion of Notices ojBirths, Marriages, and Deaths.

HARROW HOSPITAL.—Last year each in-patientcost an average of,c3 5s. 9d. per week, as against £2 12s. inthe preceding year. The average total costs of each patient-j67 10s.-includes 844 out-patients. The hospital was closedfor six weeks last summer for alterations necessitated by theextension schemes.