National Alliance for Medical Image Computing NA-MIC Work of Tannenbaum Group Computer Science and...

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National Alliance for Medical Image Computing http://www.na-mic.org NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University

Transcript of National Alliance for Medical Image Computing NA-MIC Work of Tannenbaum Group Computer Science and...

Page 1: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

NA-MIC Work of Tannenbaum Group

Computer Science and Mathematics

Stony Brook University

Page 2: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

In collaboration with (no particular order):

Steven HakerTauseef ur-RehmanAyelet DominitzEric PichonDelphine NainYi GaoIvan KolesovLiangJia ZhuSamuel DambrevilleJames MalcolmGanesh Sundaramoorthi

Behnood GholamiMarc NiethammerOleg Michaelovich Namrata VaswamiPeter KarasevArie NakhmaniYogesh RathiPatricio VelaVandana MohanShawn LanktonGozde Unal

Students and Postdocs

Page 3: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Assorted Projects

• Segmentation: Local/Global, Sobolev, Finsler, Steerable, Optimal Control

• Shape Theory: Spherical Wavelets, OMT

• Registration: OMT, Particle Filtering, Optimal Control

• Meshing (hexahedral)

• Conformal maps (brain warping, colon fly-throughs)

Page 4: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

KSlice Interactive Segmentation

Added Features:● Editor module● Inter-slice interpolation● Control of user input function● Choice for image cost

functional● Selection of tools for input

Page 5: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

3D Interactive Segmentation

GrowCut methodEasy for user interaction

Slow for 3D images

Level sets methodFlexible to segment complex structures

Rely on good initialization

3D interactive segmentationFast GrowCut for initialization

Level sets refinement, Slicer modules e.g. KSlice

Page 6: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Comparison

Method Segmentation time (seconds) Memory (MB)

Quantitative

1st edit 2nd edit 3rd edit Dice Vol. Overlap

GrowCut 210 255 269 200 97% 97%

Proposed 28 3 3 522

GrowCut:

Proposed:

Lung segmentation: image ROI [503 333 43]3 rounds of interaction/editing

Page 7: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Apr 21, 20237

Particle Filtering

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National Alliance for Medical Image Computing http://www.na-mic.org8

Particle Filtering

Page 9: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Particle Filtering Registration

Page 10: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Page 11: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Longitudinal shape analysis

Page 12: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Traumatic Brain Injury

Page 13: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Fibrosis distribution analysis

AFib recurrence after RF ablationGroup 1, cured

Group 2, recurrence

Hypothesis: Group-wise difference between 1 and 2

Shape and fibrosis (intensity) distribution

Page 14: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Results

Gray: no-statistical difference. Color region: statistically different regions.

Page 15: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Hexahedral Meshes

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National Alliance for Medical Image Computing http://www.na-mic.org

Future Work• Compressive Sensing/Mass Spec/Raman

Spectroscopy for better tumor margin delineation (Nathalie Agar, Alex Golby, Yi Gao)

• DECS for neurosurgery/validation (Sonia Pujols, Yi Gao)

• Microanatomical imaging (Joel Saltz)

• Radiation oncology (Harini V., Joe Deasy, Greg Sharp, Ivan Kolesov, Yi Gao)

• Fibrosis analysis (Rob MacLeod, Josh Cates, Yi Gao, LiangJia Zhu)

Page 17: National Alliance for Medical Image Computing  NA-MIC Work of Tannenbaum Group Computer Science and Mathematics Stony Brook University.

National Alliance for Medical Image Computing http://www.na-mic.org

Conclusions

Thank you to all the collaborators and especially to Ron Kikinis for giving us this great opportunity!

May the Force be with you and Slicer.