Nano-Tera 2016 State of the Art

Nano-Tera.ch

April 25th, 2016

Engineering Complex Systems

Nano-Tera.ch

A very successful Swiss research program

funding large collaborative multi-disciplinary projects

aiming at the engineering of complex systems

for applications in the domains of Health

and the Environment

Research, Design & Engineering of complex tera-scale systems using nano-scale devices and technologies

www.nano-tera.ch

Nano-Tera.ch: Key figures

• 140 Projects funded overall• 50 Swiss Research institutions (involved with PIs or CoPIs)• 1200 Researchers• 310 PhD students involved overall (> 240 funded by NT)• Most RTD projects receive support from various industrial partners and

hospital end-users

Number of RTD projects

Number of industrial/ hospital partners

Contributions (CHF)

Phase I 27 30 6’649’574

Phase II 25 59 8’965’813

52 89 15’615’387

38 Swiss institutionscurrently involved

ETH

-Boa

rdO

PET

SUK

/ CU

S

Federal Institute of Metrology METAS

Hos

pita

ls

Distribution of research groups

Distribution of research groupscurrently involved

Node size ~ Nb. of involved research groups Line size ~ Nb. of collaborations

160 research groups

38 institutions

• 857 Papers published overall

• ~1500 Presentations in conference and workshops worldwide

• 43 Awards received by Nano-Tera researchers

• 32 Patents applications filed

Dissemination statistics

Phase I(completed)

Phase II(as of 2014)

Total(as of 2014)

Journals, books 324 111… 435…

Conf. proceedings 413 204… 617…

737 315… 1052…

Phase I Phase II Total1’265 574… 1’839…

Phase I Phase II Total37 17… 54…

Phase I Phase II Total24 19… 43…

Main research directions

SmartGrid

HeatReserves

SHINEMIXSEL II

WearableMRIWearMeSoC

BodyPoweredSenSE

UtraSoundToGoObeSense

ISyPeM II

Envirobot

X-Sense II

IrSens II

WiseSkin

HearRestore

SmartSphincter

SpineRepair

MagnetoTheranostics

YINS

IcySoC

Synergy

OpenSense II

FlusiTex

NewbornCare PATLiSci II

Health Monitoring

Smart Prosthetics & Body Repair

Medical Platforms

Smart Energy

Health Environment Energy

Environmental Monitoring

call 2011 call 2012 call 2013

Bridge Program

Bridge

Nano-Tera.ch strives to enable mechanisms that can map the high productivity of research ideas, publications and patents of the Swiss community into a significant momentum in terms of industrial growth as well as job and enterprise creation.

In this perspective, Nano-Tera.ch first strongly contributed to the design of the Bridge, a special program the Swiss Confederation is planning for the 2017-2020 budgetary cycle to accelerate the transfer of research results and their applications.

Bridge

As indicated in the draft Federal message for the promotion of Education, Research and Innovation, the Bridge program:

• shall support researchers who identify the potential for applications in the form of a product or a service, but still need to carry out further work in order to make their idea more precise and prove its potential.

• will be piloted jointly by SNF and CTI.

Bridge

The Federal Council is planning a total budget of 70 MCHF for the Bridge program, equally distributed between SNF and CTI.

Two types of activities should be funded:• Proof of concept support for young researchers who wish to

exploit the economic potential of their scientific results – and pursue their career outside of academia.

• Pre-competitive projects combining research excellence with a clear technological innovation perspective within smaller size consortia.

Gateway Program

Gateway

Nano-Tera.ch also joined efforts with CSEM and EMPA to embody several of the core ideas developed during the design of Bridge into a specific pilot program:

Gateway

Intrinsically positioned at the frontier between research and innovation, it aims at the translation of research results obtained within Nano-Tera.ch projects into industrial demonstrators directly exploitable by the involved industrial partners.

ValueIgnorance

Performance metric

Reasoning Exploratory Causal

Profitability

External constraints Weakly considered Strongly considered

Scientific excellence

TRL2: Knowledge creation (publications) TRL3: Technological componentsTRL4: Laboratory prototype

Research

TRL 3 4 5 6 7 82 9

TRL7: Validated demonstratorTRL8: System & Business ModelTRL9: Economic value creation (profit)

Valorization

Involvement of indus. partners

(confidence)

TRL5: Functional demonstratorTRL6: Operational demonstrator

GATEWAY

Gateway

Gateway

The Gateway program has been concretely set up as follows:

• Selection of the NT projects involving an industrial partner able to efficiently support translation of research results into activities with high economic potential and corresponding to the best compromise between economic potential and industrial risk.

• Set up a specific monitoring mechanism under the supervision of a dedicated innovation manager.

Gateway

The deployment of the Gateway program resulted in the selection of 4 proposals with high potential for industrial impact for a total Nano-Tera.ch funding of 946’000 CHF.

These projects, which all started in October 2015 and will last 18 months, involve laboratories, institutions specialized in technology transfer (EMPA and CSEM) as well as industrial partners.

The goal of these projects is to convert laboratory prototypes resulting from Nano-Tera.ch research projects (Technology Readiness Level 4) into industrial demonstrators (TRL 6-7) with high economic potential.

Gateway

Gateway proposal

Related NT project

Partners Aim

SYNGATE Synergy CSEM, EMPAMeyer BurgerSolaronixFlisom

High-performance/flexible perovskite tandem solar cells

FLUSIGATE FlusiTex EMPA, CSEMFlawa, Kenzen Schöller Textil,Theranoptics

Fluorescence based PH sensing wound monitoring pad

HEARGATE HearRestore CSEMAtracsys

Metrology module for a surgical navigation system

PARAGATE ParaTex EMPAForster RohnerMeister & CieArt of Technology

Pressure/oxygenation/perfusion monitoring textile sensor for pressure ulcer detection

Focus on PhD students:the Nano-Tera NextStep Program

NextStep Program

They can get together with other PhD students to develop a collaborative research project

They can learn how to exploit the economic potential of their research and how to present business ideas

How do PhD students benefit from the program?

Receive funding for their proposal

Coaching program & Entrepreneurial

pitches

Track 2 – Entrepreneurship

Track 1 – Scientific Collaboration

Track 3 – Scientific DisseminationThey can learn to present their scientific achievements to a general audience

My Thesis in 180 Seconds contest

NextStep program:Collaborative research track

The objective of the Collaborative research track of the NextStep action is to give Nano-Tera.ch PhD students the opportunity to consider the development of a collaborative work, within the framework of their thesis.

Concretely, this track gives the students the opportunity to learn the full procedure of submitting proposals to get concrete funding: from building a consortium, picking the research challenges, writing the scientific proposal, and building a reasonable budget.

These efforts results in the funding of 7 ‘ED’ projects submitted by Nano-Tera.ch PhD students – presented later today at 17:10.

Name NT Project Acronym TitleT. Brusa, UniBEPI: P. Büchler

SmartSphincter BAFIARS Assessment of anatomic, physiologic & biomechanical characteristics of the anal canal & pelvic floor: an observational study in patients

M. Thielen, ETHZPI: C. Hierold

BodyPoweredSenSE BioFlex Soft dry Biopotential Electrodes for Long-Term EEG recording

T. Wyss, UniBEPI: P. Büchler

HearRestore BonePro HearRestore: Bone Impedance modelling

P. A. Hager, ETHZPI: L. Benini

UltraSoundToGo LightProbe Digital UltraSound Head

J. Ansó, UniBEPI: S. Weber

HearRestore NerveSafe Facial nerve monitoring during robotic cochlear implantation

D. Mikulik, EPFLPI: A. Fontcuberta

Synergy SolCelMeas Analyzing of optical and electrical measurements of GaAs nanowire solar cells

H. Huang, BFHPI: V. Koch

WiseSkin MultiHaptic Human study: info transfer analysis & early eval. Of multi-modality haptic displays for sensory feedback

NextStep program:Collaborative research track

NextStep program: Entrepreneurship track

The objective is to develop an “early-stage entrepreneurial mindset” for the Nano-Tera.ch PhD students.

Activities include:• Extended support for the 4 entrepreneurial projects selected by

the Nano-Tera Executive Committee during the Annual Meeting 2015 (Business coaching and participation to adequate high impact events)

• Setup of a Nano-Tera.ch “entrepreneurial pitch” contest including individual coaching for the involved PhD students.

The results of these efforts will be showcased later today at 16:45.

MT180 action

Apart from performing excellent science, it is important for junior researchers to communicate their work and results in a clear and appealing way, easily understandable outside their field of specialization.

To this end, Nano-Tera has organized an MT180 (“My Thesis in 180 Seconds”) contest, where NT PhD students have 3 minutes to present the content of their research to a wide audience, with the support of only one static slide.

This contest:• gave 6 of the PhD students the opportunity to benefit from personal

coaching under the supervision of 6 members of the Swiss Association of Science Journalists

• built a bridge toward the Swiss media

MT180 action

The results of these efforts is the selection of the 3 best presentations for the MT180 final which will take place this afternoon at 18:10.

The attribution of the best Nano-Tera MT180 presentation will be the result of a vote by the whole Nano-Tera audience present this afternoon.

Statistics on former Nano-Tera.ch PhD students

To industry or to academia? (of 156 NT graduates)

Academia

40%

Industry55%

Unem-ployed,

Un-known

5%

If in academia, where?

Switzer-land52%Europe

16%

United States21%

Other11%

If in industry, where?

Switzer-land 72%

Europe 15%

United States 11%

Other2%

Industry size

Micro (1-10)14%

Small (10-50)

9%

Medium(50-200)11%

Large (200+)66%

Micro: 1-10 Employees• Giulia Cappi ISyPeM –> Lunaphore (Start-Up)

• The multi-disciplinary, industry oriented approach enabled by her NanoTera project proved fundamental to her new job as a Project Manager in a promising young EPFL start-up.

• Andrea Cavallini IronIC –> Qloudlab (Start-Up)• Multidiscipilanry project, especially related to health

monitoring and biosensing. This gave him the bases for his current job, where we design and test a novel connected mobile health device.

Examples of Nano-Tera.ch PhD involvement in industry


Small/Medium: 11-250 Employees• Armin Tajalli ULP-Logic –> Kandou Bus (Start-Up)

• Working on low power electronics taught him a number of skills now applied to his new job. These include circuit design tool expertise, instrumentation as well as practical circuit efficiency trade-offs and properties.

• Wenqi You ISyPeM –> Sophia Genetics (Start-Up)• Her NanoTera project provided the skills in Big Data

analysis and the programming skills she is currently applying in her position as a Senior Data Analyst.

Large industries – 250+ Employees


• Aravind Heragu ISyPeM –> Semtech Neuchâtel (CH)• I worked on designing a 2.4GHz low power radio for the

biotelemetry application targeted in the ISyPeM project. This was indeed a major requirement to become a RF engineer, and my PhD work helped in a great deal.

• Yuksel Temiz CMOSAIC –> IBM Research Zurich (CH)• He was involved in 3 different NanoTera projects. This gave

him the chance to work in a multi-disciplinary research environment with people from different fields. His position as a Post-Doc at IBM stems from this experience.

Start-ups involving Nano-Tera.ch PhD students

NT PhD students active in startups (21 cases)

Surname First name Location Start-up size Job function Current employer

Accastelli Enrico DE 11-50 R&D engineer TissUse BerlinCappi Giulia CH 1-10 R&D engineer LunaphoreCavallini Andrea CH 1-10 R&D engineer QloudlabFateh Schekeb CH 1-10 R&D engineer ACP Advanced Circuit PursuitHenriksson Jonas CH 1-10 R&D engineer FemtoToolsHoffmann Martin CH 1-10 Co-founder TechnisKnopfmacher Oren US 1-10 Co-founder and CEO Avails MedicalMeissner Robert CH 1-10 Founder OncoEffectiveMerulla Davide CH 11-50 R&D engineer NanoliveNagy Zoltan CH 11-50 Co-founder FemtoToolsPeikert Vincent CH 11-50 Co-founder Elevence Digital FinancePinto Christian FR 11-50 R&D engineer Virtual Open SystemsRaghav Shivani CH 1-10 R&D engineer for 4 months Iprova SarlRentero Inmaculada CH 1-10 R&D engineer AnokionRossier Michael CH 1-10 R&D engineer for 3 years NanogradeSchyrr Bastien CH 1-10 Co-founder TheranopticsTaddeo Antonio CH 1-10 Founder Dolphin Engineering Tajalli Armin CH 11-50 R&D engineer Kandou BusWojtas Nina CH 1-10 Co-founder and technical director EMFabYou Wenqi CH 51-250 R&D engineer Sophia GeneticsZagolla Volker CH 11-50 R&D engineer Lemoptix, acquired by Intel 2015

Examples ofStart-ups created by Nano-Tera.ch

PhD students

Start-ups created by Nano-Tera.ch PhD students

Technis, Lausanne

Martin Hoffmann - MIXSEL


Technis, Lausanne


FemtoTools, Buchs

Zoltan Nagy - SelfSys


Technis, Lausanne


FemtoTools, Buchs


Elevence Digital Finance, Zurich

Vincent Peikert - Enabler


Technis, Lausanne


FemtoTools, Buchs




Dophin Enginering, Lugano

Antonio Taddeo - SecWear


Technis, Lausanne


FemtoTools, Buchs






EMFab, Schlieren

Nina Wojtas - BodyPoweredSenSE


Technis, Lausanne


FemtoTools, Buchs






EMFab, Schlieren

Nina Wojtas - BodyPoweredSenSE

Avails Medical, Palo Alto, USA

Oren Knopfmacher - NanowireSensor

Examples ofsuccessful start-ups involving

Nano-Tera.ch PhD students

Successful start-ups involvingNano-Tera.ch PhD students

Lunaphore, Lausanne (2 MCHF Series A funding)

Giulia Cappi - ISyPeM


Lunaphore, Lausanne


Anokion, Préverenges (37 MCHF Series A funding)

Inmaculada Rentero - ISyPeM


Lunaphore, Lausanne


Anokion, Préverenges (VD)


Sophia Genetics, LS (31.5 MCHF Series A/B/C funding)

Wenqi You- ISyPeM


Lunaphore, Lausanne




Sophia Genetics, Lausanne

Wenqi You- ISyPeM

Lemoptix, Lausanne

Volker Zagolla- SHINE

Acquired by Intel


Lunaphore, Lausanne





Wenqi You- ISyPeM

Lemoptix, Lausanne

Volker Zagolla- SHINE

Acquired by IntelSmartCardia, Lausanne

Srinivasan Murali – BioCS-Node

Project involving undergraduates

beMap project

Benjamin, Chloe, Yoann and Micha

beMap project

TeamBenjamin, Chloe, Yoann and Micha, EPFL 3rd year Bachelor microengineering students

Objective of the projectBicycle Environmental Mapping (beMap): a bike lamp featuring GPS tracking and sensors measuring air pollution along a cycling route.Cyclists can gather pollution data about the air they breathe on their way to work in order to choose their route accordingly.

HistoryProject developed for iCan contest 2015Awarded 2nd price at the international final at IEEE transducers Anchorage 2015

Future stepsBrazil Mapping parties and presentation to local makers with Swissnex

Thanks for your attention!

Visit us at www.nano-tera.ch www.nano-tera.ch

Technis, Lausanne

Technis, Lausanne

• Develops a new generation of tennis courts, which is touch sensitive and understands what is happening on the surface. Using these new tech-enabled courts as a platform, they combine technology and sports in an integrated and seamless way.

• Start-up founded in 2014• Fundraising: CHF 50’000 (2015) from Swiss Startups.ch• Awards:

– Swiss startups.ch award 2015– Venture kick I and II– Start Lausanne

• Website: www.mytechnis.ch• Involved person: Martin Hoffmann (PhD ETHZ 2011), Co-founder• Further info:

– https://www.linkedin.com/in/chmhofmann– https://startupmonitor.ch/startups/2213/technis/– http://startupticker.ch/en/news/october-2015/swiss-startups-awards-2-des-4-prix-sont-

remportes-par-des-projets-provenant-de-suisse-romande

http://www.mytechnis.ch/

https://www.linkedin.com/in/chmhofmann

https://startupmonitor.ch/startups/2213/technis/

FemtoTools, Buchs

FemtoTools, Buchs

• FemtoTools is a Swiss high-tech company that offers award-winning, ultra high-precision instruments for mechanical testing and robotic handling in the micro- and nanodomains.

• Start-up founded in 2007• Funding: Capital CHF 900’000• Awards:

– Swiss Technology Award 2009– CTI– Venture Leader– RBR50 - Top 50 most Influental Robotics Companies Worldwide in 2014

• Website: www.femtotools.ch• Involved persons:

– Nagy Zoltan (PhD ETHZ 2011), Co-founder– Jonas Henriksson (PhD EPFL 2014), Employee

• Further info:– www.linkedin.com/in/zoltan-nagy-45605114 http://www.zoltan-nagy.net/– http://www.swissventureguide.ch/2012/Start-Ups-on-the-Way-to-Success/FemtoTools– http://www.roboticsbusinessreview.com/rbr50/companies/Private

http://www.femtotools.ch/

http://www.linkedin.com/in/zoltan-nagy-45605114

http://www.zoltan-nagy.net/

http://www.swissventureguide.ch/2012/Start-Ups-on-the-Way-to-Success/FemtoTools

http://www.roboticsbusinessreview.com/rbr50/companies/Private


• Elevence develops and commercializes a scalable distributed digital ledger system to exchange, administrate and audit financial contracts.

• Start-up founded in 2015• Funding: Capital CHF 300’000• Website: www.elevence.com• Involved person: Vincent Peikert (PhD ETHZ 2013), Co-founder• Further info:

– https://www.linkedin.com/in/dr-vincent-peikert-81079098– https://www.xing.com/news/klartext/elevence-sind-junge-revolutionare-240

http://www.elevence.com/

https://www.linkedin.com/in/dr-vincent-peikert-81079098

https://www.xing.com/news/klartext/elevence-sind-junge-revolutionare-240

Dolphin Engineering, Lugano

Dolphin Engineering, Lugano

• Provides a service able to monitor the micro-climate conditions of cultivated fields in order to prevent plant diseases.

• Start-up founded in 2007• Funding: CHF 7’500 (InnovationsCheck 2009), CHF 30’000

(Microcredito città di Lugano 2012)• Awards:

– CTI– Microcredito città di Lugano

• Website: www.dolphin-engineering.ch• Involved person: Antonio Taddeo (PhD USI, 2011), Co-founder• Further info:

– www.linkedin.com/in/antonio-vincenzo-taddeo-7110257– http://www.dolphin-engineering.ch/CdT-SchedaDolphin.pdf

http://www.dolphin-engineering.ch/

http://www.linkedin.com/in/antonio-vincenzo-taddeo-7110257

http://www.dolphin-engineering.ch/CdT-SchedaDolphin.pdf

EMFab, Schlieren

EMFab, Schlieren

• The core businesses of EMFab include three main fields: design and engineering services, mechanical machining, and PCB (printed circuit board) manufacturing.

• Start-up founded in 2014• Funding: CHF 20’000 (2014)• Website: www.emfab.ch• Involved person: Nina Wojtas (PhD ETHZ, 2014), Co-founder• Further info:

– www.linkedin.com/in/nina-wojtas-170a8289– http://www.moneyhouse.ch/en/u/emfab_gmbh_CH-020.4.053.204-4.htm

http://www.emfab.ch/

http://www.linkedin.com/in/nina-wojtas-170a8289

http://www.moneyhouse.ch/en/u/emfab_gmbh_CH-020.4.053.204-4.htm


• Avails Medical is revolutionizing the current diagnostics market with a unique platform that transforms biochemical reactions to electrical signals.

• Start-up founded in 2013• Funding: $ 1'250'000 (2014)• Website: www.availsmedical.com• Involved person: Oren Knopfmacher (PhD UniBAS 2011),

Co-founder and CEO• Further info:

– http://www.linkedin.com/in/knopfmacher– https://angel.co/avails-medical– http://form-d.findthecompany.com/l/164607/Avails-Medical-Inc

http://www.availsmedical.com/

http://www.linkedin.com/in/knopfmacher

https://angel.co/avails-medical

http://form-d.findthecompany.com/l/164607/Avails-Medical-Inc

Lunaphore, Lausanne

Lunaphore, Lausanne

• Lunaphore has developed an innovative tissue diagnostics platform, primarily for analysis and classification of tumors. The platform is based on a microfluidic chip technology that allows fine-tuning of such diagnostic assays and increases their speed and accuracy.

• Start-up founded in 2014• Size: 1-10 employees• Fundraising: CHF 130'000 Venture Kick final (2015),

CHF 2'000'000 Series A funding (2015)• Awards:

– TOP100 Swiss startups (top 10)– Venture kick– Sanofi-Aventis Science4Life

• Website: www.lunaphore.ch• Involved person: Giulia Cappi - ISyPeM (employee)

Prof. Martin Gjis (advisor)


• Anokion, a spin-off from the Ecole Polytechnique Fédérale de Lausanne (EPFL), is focused on applying the company’s antigen-specific immune tolerance technology to reduce the immunogenicity of therapeutic proteins and to treat autoimmune and allergic diseases. As a platform technology, Anokion’s approach to antigen-specific tolerance can be translated to virtually any protein in numerous clinical indications.

• Start-up founded in 2010• Size 1-10 employees• Funding: $ 37’000’000 Series A funding• Website: www.anokion.com • Involved person: Inmaculada Rentero, Employee• Further info:

– https://www.linkedin.com/in/dr-vincent-peikert-81079098– https://www.xing.com/news/klartext/elevence-sind-junge-revolutionare-240

http://www.anokion.com/

https://www.linkedin.com/in/dr-vincent-peikert-81079098

https://www.xing.com/news/klartext/elevence-sind-junge-revolutionare-240


• Sophia Genetics is the Global Leader in Data Driven Medicine. Our team of talented experts in Clinical Genomics, Machine Learning and Bioinformatics built Sophia DDM®, the most advanced genomics data analytics platform. Over 150 leading hospitals use Sophia DDM® to diagnose thousands of patients each week in the fastest, most accurate possible way.

• Start-up founded in 2011• Size: 51+• Funding:$ 2'800'000 Series A funding,

$ 13'750'000 Series B funding (2014),$ 15'000'000 Series C funding (2015)

• Website: www.sophiagenetics.com• Involved person: Wenqi You (employee)

Lemoptix, Lausanne

• Lemoptix is a leading developer of laser microprojection technology for next generation mobile augmented reality and human/machine interaction. The company develops and commercializes advanced microprojection technology, integrating proprietary micro-electro-mechanical systems (MEMS)-, driving electronics and optics sub-systems.

• Start-up founded in 2008• Funding: Four funding rounds of undisclosed amounts (2011-2014).

Acquired by Intel for an undisclosed amount in 2015• Website: not active after the acquisition by Intel• Involved person: Volker Zagolla (employee)

Nano-Tera 2016 State of the Art

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