Modes of Ventilation - NRRCC 2007.pdf

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    Mechanical VentilationMechanical VentilationUnderstanding ModesUnderstanding Modes

    Rob Chatburn, RRTRob Chatburn, RRT--NPS, FAARCNPS, FAARC

    Research ManagerResearch Manager Respiratory TherapyRespiratory Therapy

    Cleveland ClinicCleveland Clinic

    Associate ProfessorAssociate Professor

    Case Western Reserve UniversityCase Western Reserve University

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    OverviewOverview

    Characteristics of modes Pressure control vs volume control

    Graphical representations of modes Breath types

    Mandatory vs spontanous

    Assisted vs unassisted

    Breathing patterns Definitions, indications, examples

    Graphical representations

    Computer control of mechanicalventilation

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    Characteristics of a ModeCharacteristics of a Mode

    1. Breathing Pattern Control variable

    Breath sequence

    2. Control Type Setpoint, auto-setpoint, servo, adaptive, optimal

    3. Control Strategy

    Phase variables

    Operational logic

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    Control VariablesControl Variables

    Ventilator can control only one variable at a timeIndependent variable is control variable

    Pvent = E x V + R x V

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    Volume ControlVolume Control

    Tidal volume and flow presetAirway pressure changes with lung

    mechanics

    Advantage:

    Minute ventilation and gas exchange stable

    Disadvantage:

    Volume and flow may not be optimal

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    Pressure ControlPressure ControlAirway pressure preset

    Volume and flow change with lungmechanics

    Advantage: Better patient flow synchrony

    Possibly better oxygenation

    Potentially reduced risk of volutrauma

    Disadvantage:

    Gas exchange may not be stable

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    VolumeVolume

    ControlControlInfluenceInfluence

    DiagramDiagram

    MinuteVolume

    TidalVolume Rate

    CycleTime

    Inspiratory

    Time

    Expiratory

    Time

    I:E

    Inspiratory

    Flow

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    PressurePressure

    ControlControlInfluenceInfluence

    DiagramDiagram

    MinuteVentilation

    VentilatoryFrequency

    TidalVolume

    InspiratoryTime

    ExpiratoryTime

    I:E Ratio

    PressureGradient

    PeakInspiratoryPressure

    EndExpiratoryPressure

    Resistance

    TimeConstant

    Compliance

    Mean

    AirwayPressure

    ContinuousFlow Rate

    (Affects shapeof pressurewaveform)

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    0 Time (s)

    Inspiration Expiration

    Volume/Flow ControlVolume/Flow Control

    0 Time (s)Flow

    Pressure Paw

    Volume Plung

    Paw

    Inspiration Expiration

    Pressure ControlPressure Control

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    Dual ControlDual Control Volume control to Pressure Control:

    Attempts to deliver a constant tidal volume whilelimiting peak pressure

    Pressure control to Volume Control:

    Attempts to limit peak pressure but assures tidalvolume delivery

    Disadvantage:

    Requires high degree of understanding

    Difficult to adjust and maintain

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    Characteristics of a ModeCharacteristics of a Mode

    1. Breathing Pattern Control variable

    Breath sequence

    2. Control Type Setpoint, auto-setpoint, servo, adaptive, optimal

    3. Control Strategy

    Phase variables

    Operational logic

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    Breath TypesBreath Types

    What is the difference between

    mandatory and spontaneous breaths?

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    Spontaneous

    yes

    no

    Breath TypesBreath Types

    Patient

    controlssize

    yes

    Mandatory

    no

    Think

    Patient

    controlsstart

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    Definition of Assisted BreathDefinition of Assisted Breath

    Assisted Ventilator does work on patient.

    Un-Assisted

    Ventilator does no work on patient. Loaded (work imposed on patient)

    Patient does work on ventilator.

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    Identification of Assisted BreathsIdentification of Assisted Breaths

    Assisted

    Airway pressure rises above baseline duringinspiration (or falls below baseline duringexpiration).

    Un-Assisted Airway pressure stays constant during inspiration

    or expiration.

    Loaded (work imposed on patient) Airway pressure falls below baseline during

    inspiration and rises above baseline duringexpiration.

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    Assisted Spontaneous BreathsAssisted Spontaneous Breaths

    Pressure Support Volume Support

    Automatic Tube Compensation Proportional Assist Ventilation

    SmartCare

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    Potential ConfusionPotential Confusion

    An assisted breath may bespontaneous or mandatory

    A spontaneous breath may beassisted or unassisted

    A mandatory breath is assisted by

    definition

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    Characteristics of a ModeCharacteristics of a Mode

    1. Breathing Pattern

    Control variable

    Breath sequence

    2. Control Type Setpoint, auto-setpoint, servo, adaptive, optimal

    3. Control Strategy

    Phase variables

    Operational logic

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    Continuous MandatoryContinuous Mandatory

    Ventilation (CMV)Ventilation (CMV)

    Mandatory breaths Machine triggered and/or machine cycled

    Spontaneous breaths

    During mandatory breaths only, not between

    Key clinical concept

    Level of support independent of frequency (ifpatient is breathing)

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    Intermittent MandatoryIntermittent Mandatory

    Ventilation (IMV)Ventilation (IMV)

    Mandatory breaths Machine triggered and/or machine cycled

    Spontaneous breaths

    Between and during mandatory breaths

    Key clinical concept

    Level of support is proportional to set frequency(if spontaneous breaths unassisted)

    Historically used as a mode of weaning

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    Continuous SpontaneousContinuous Spontaneous

    Ventilation (CSV)Ventilation (CSV)

    All breaths spontaneous Patient triggered and cycled

    No backup rate in case of apnea

    Breaths may or may not be assisted

    Full support may be achieved (if no apnea)

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    Characteristics of a ModeCharacteristics of a Mode

    1. Breathing Pattern

    Control variable

    Breath sequence

    2. Control Type Setpoint, auto-setpoint, servo, adaptive, optimal

    3. Control Strategy

    Phase variables

    Operational logic

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    8 Basic Breathing Patterns8 Basic Breathing PatternsControl

    Variable

    Breath

    Sequence Symbol

    Continuous Mandatory Ventilation VC-CMV

    Intermittent Mandatory Ventilation VC-IMV

    Continuous Mandatory Ventilation PC-CMV

    Intermittent Mandatory Ventilation PC-IMV

    Continuous Spontaneous Ventilation PC-CSV

    Continuous Mandatory Ventilation DC-CMV

    Intermittent Mandatory Ventilation DC-IMV

    Continuous Spontaneous Ventilation DC-CSV

    Dual

    Pressure

    Volume

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    VCVC--CMVCMV

    Often referred to as Assist/Control

    Characteristics

    VC results in more even distribution of ventilationamong lung units with equal resistance and unequalcompliance than PC

    Selection of flow and sensitivity is critical

    Indications Need for total ventilatory support

    Need for precise regulation of blood gases

    Example Precise regulation of PaCO2 in patients with traumatic

    brain injury

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    VCVC--CMVCMV

    waveformswaveforms

    Ven

    tilato

    r

    Pressu

    re

    Vo

    lume

    Flo

    w

    Mu

    sc

    le

    Pressure small

    inspiratory

    effort

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    A B C

    patient

    triggered

    machine

    triggered

    reducedpressure

    indicates patient

    effort throughoutinspiration

    set tidal volume

    setflow

    VC IMV

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    VCVC--IMVIMV

    Characteristics Spontaneous breaths may be assisted

    Selection of mandatory flow and spontaneouspressure support critical

    Indications Relatively normal lung function

    Rapid recovery from sedation or respiratory failure

    Recent data suggest it is worst choice for weaning

    ExampleTreatment of neuromuscular disease like Gullian-Barre syndrome

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    VCVC--IMVIMV

    waveformswaveforms

    Ven

    tilato

    r

    Pressur

    e

    Vo

    lume

    Flo

    w

    Mus

    cle

    Pres

    sure small

    inspiratory

    effort

    no

    inspiratory

    effort

    A B C

    patient

    triggered

    machine

    triggered

    medium

    inspiratory

    effort

    setpressure support

    settidal volume

    setflow

    Are spontaneous

    breaths assisted?

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    PCPC--CMVCMV Characteristics

    PC results in more even distribution of ventilationamong lung units with equal compliance and unequalresistance than VC

    Pressure control results in higher mean airway

    pressure and earlier lung opening than VC

    Indications Problems with oxygenation or synchrony

    Example Treatment of ARDS patients with oxygenation

    problems

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    PCPC--CMVCMV

    waveformswaveforms

    Ven

    tilat

    or

    Pressure

    Vo

    lume

    Flo

    w

    Musc

    le

    Pres

    sure small

    inspiratory

    effort

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    A B C

    patient

    triggered

    machinetriggered

    time cycled

    setpressure limit

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    PCPC--IMVIMV Characteristics

    Relatively simple mode Used historically for infants

    Spontaneous breaths may be assisted

    Indications Problems with oxygenation or synchrony

    Adequate ventilatory drive

    Example Treatment of premature infants with RDS

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    PCPC--IMVIMV

    waveformswaveforms

    Ven

    tilato

    r

    Pressure

    Vo

    lume

    Flo

    w

    Mus

    cle

    Pressure large

    inspiratory

    effort

    no

    inspiratory

    effort

    A CBmedium

    inspiratory

    effort

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    PCPC--CSVCSV

    Characteristics No assist = CPAP

    Assist Pressure Support

    Proportional Assist

    Automatic Tube Compensation

    Indications Weaning

    Reduce work of breathing or stabilize oxygenation Examples

    Nasal CPAP for neonates recovering from RDS

    Noninvasive ventilation of adults

    A B C

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    PCPC--CSVCSV

    waveformswaveforms

    Spontaneous

    breaths are not

    assisted

    (CPAP)

    Ven

    tila

    tor

    Pressu

    re

    Vo

    lume

    Flo

    w

    Mu

    sc

    le

    Pre

    ssure small

    inspiratory

    effort

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    A B C

    DCDC CMVCMV

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    DCDC--CMVCMV

    Characteristics

    Mandatory breaths adapt to changing lungmechanics

    Indications

    Unstable lung mechanics or ventilatory drive

    Example

    Treatment of patient with pneumonia andintermittent secretion problems

    A B

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    DCDC--CMVCMV

    waveformswaveforms

    Ven

    tilato

    r

    Pressu

    re

    Vo

    lume

    Flo

    w

    Mu

    sc

    le

    Pres

    sure

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    A B

    patient

    triggered

    pressure limit

    over-ridden

    set volume target volume cycled

    flow cycledsetflow limit

    setpressure limit

    switch frompressure control

    to volume control

    volume target

    not met

    inspiratory flowequals flow limit

    volume metbefore

    flow decays to set limit

    pressure-to-volume

    Bird VAPS

    A B

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    DCDC--CMVCMV

    waveformswaveforms

    volume-to-pressure

    DrgerPressure Limited

    VentilationV

    en

    tilato

    r

    Pressu

    re

    Vo

    lume

    Flo

    w

    Mu

    sc

    le

    Pre

    ssure small

    inspiratory

    effort

    A B

    set tidal volume

    volume

    limited

    plateau

    pressure

    plateau

    pressure

    set Pmax

    switch fromvolume control

    to pressure control

    volume limited

    time cycledtime cycled

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    DCDC--IMVIMV

    waveformswaveforms

    Ven

    tilato

    r

    Pressure

    Vo

    lume

    Flo

    w

    Mus

    cle

    Pressure

    A C

    plateau

    pressure

    set Pmax

    time cycled

    set Pmax

    time cycled

    set tidal volume

    setflow

    B

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    Pressure SupportPressure Support

    Pressure or flow triggered, pressurelimited, inspiratory flow cycled

    Level of ventilatory support

    determined by pressure limit

    Sometimes set to approximately

    support resistive work of breathing(through endotracheal tube)

    A B C

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    PCPC--CSVCSV

    waveformswaveforms

    Spontaneous

    breaths are

    assistedV

    en

    tilat

    or

    Pressur

    e

    Vo

    lume

    Flo

    w

    Mus

    cle

    Pressure small

    inspiratory

    effort

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    A B C

    patient

    triggered

    flow cycled

    setpressure limit

    flow cycle threshold

    pressure rise

    time

    increased

    P i l A iP ti l A i t

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    Proportional AssistProportional Assist

    flowRvolumeEP normalnormalmus +=

    ( ) ( ) flowRRvolumeEEP abnormalnormalabnormalnormalmus +++=

    ( ) ( )loadabnormalloadnormalPmus +=

    ( ) ( )loadabnormalloadnormalPP ventmus +=+

    flowRvolumeEloadabnormalP abnormalabnormalvent +==

    operator settings (volume and flow amplification factors)

    A B C

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    PCPC--CSVCSV

    waveformswaveforms

    Spontaneous breaths

    are assisted

    (Proportional Assist)V

    en

    tilat

    or

    Pressure

    Vo

    lume

    Flo

    w

    Mus

    cle

    Pres

    sure small

    inspiratory

    effort

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    A B C

    A t ti T bA t ti T b

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    Automatic TubeAutomatic Tube

    CompensationCompensation

    2flowRloadresistiveabnormalP

    tubevent

    ==

    operator sets tube diameter

    ventilator calculates resistance factor

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    Characteristics of a ModeCharacteristics of a Mode1. Breathing Pattern

    Control variable

    Breath sequence

    2. Control Type Within breaths Between breaths

    3. Specific Control Strategy Phase variables

    Operational logic

    Evolution of Ventilator Control TypesEvolution of Ventilator Control Types

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    ypyp

    PatientVentilatorOperator

    PatientVentilator

    ModelOperator

    PatientVentilator

    Model

    Strategic Control (between breaths)

    adaptive (CMV+AutoFlow)

    optimal (ASV)

    ventilator-selected, dynamic setpoints

    static model

    Intelligent Control (between patients)

    knowledge based

    arti ficial neural network

    ventilator-selected, dynamic setpoints

    dynamic modelability to learn from experience

    operator-selected, static setpoints

    Tactical Control (within-breaths)

    setpoint (PC-IMV)

    auto-setpoint (Pmax)

    servo (Automatic Tube Compensation)

    T ti l C t lTactical Control

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    Tactical ControlTactical Control

    All the modes discussed so far All require the operator to set

    Pressure (PIP, PEEP) Volume (tidal volume, minute ventilation) Flow (peak inspiratory flow)Time (inspiratory time, frequency, I:E)

    Strategic ControlStrategic Control

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    Strategic ControlStrategic Control

    Characteristics Breathing pattern may be PC-CMV, PC-IMV, PC-CSV

    Pressure limit automatically adjusted to compensate forchanges in compliance to meet target tidal volume

    Indications (Self) Weaning

    Reduce work of breathing or stabilize oxygenation Reduce clinician workload

    Examples

    Post-operative patients with normal lungs Mixed ICU patients COPD exacerbation

    A B C

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    AdaptiveAdaptive

    ControlControl

    Ven

    tilat

    or

    Pressure

    Vo

    lume

    Flo

    w

    Musc

    le

    Pres

    sure

    large

    inspiratory

    effort

    no

    inspiratory

    effort

    patienttriggeredmachinetriggered

    pressure limit

    automatically reduced

    volume targetvolume overshoot

    time cycled

    Hamilton Galileo Adaptive Support ModeHamilton Galileo Adaptive Support Mode

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    Hamilton Galileo Adaptive Support ModeHamilton Galileo Adaptive Support Mode

    Optimum control Clinician enters

    Patient ideal body weight Percent of predicted minute ventilation to support

    Ventilator monitors

    minute ventilation lung mechanics (expiratory time constant)

    Automatically adjusts minute ventilation mandatory breath frequency

    pressure limit inspiratory time

    Sets frequency to minimize WOB as if

    patient was breathing spontaneously

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    Any medicalinstrumentation that

    requires constant

    input from a human

    operator is obsoleteHamilton Medical

    Intelligent ControlIntelligent Control

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    Intelligent ControlIntelligent Control Characteristics

    Classification of patient condition Manual (eg, by diagnosis)

    Fuzzy logic Rule based expert system or artificial neural network

    Indications

    Weaning Respiratory failure of various typesTrauma

    Examples Post-operative patients with normal lungs Mixed ICU patients Emergency department

    C i l E lC i l E l

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    Commercial ExampleCommercial Example

    SmartCare (Drger Evita XL) Knowledge Based Control

    1. Automatically adjust pressure support: breathing rate, tidalvolume and end tidal CO2.2. Automatically test patient tolerance of a lower pressure

    support level without leaving the comfort zone.3. Attempts extubation with PS at resistive WOB.

    Artificial intelligence Fuzzy logic interprets patient condition Rule based expert system treats condition

    Operator sets patient weight history (neuro or COPD) type of airway

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    Characteristics of a ModeCharacteristics of a Mode1. Breathing Pattern

    Control variable

    Breath sequence

    2. Control Type Setpoint, auto-setpoint, servo, adaptive, optimalknowledge based

    3. Specific Control Strategy Phase variables

    Operational logic

    Mode Description UtilityMode Description Utility

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    Mode Description UtilityMode Description Utility

    Describe the difference in modes

    Pressure Support

    Volume Support

    Describe the difference in ventilators

    Pressure support (PB7200)

    Pressure support (Servo-i)

    Mode Description SummaryMode Description Summary

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    p yp y

    (without the brand jargon)(without the brand jargon)

    Pressure Support

    Only Level 1 needed

    PC-CSV

    Volume Support Requires Level 2

    PC-CSV with adaptive control

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    Adaptive Pressure ControlAdaptive Pressure Control Pressure Regulated Volume Control

    AutoFlow

    VC+

    PC-SIMV + Volume Guarantee

    Mode Description SummaryMode Description Summary

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    p y

    (without the brand jargon)(without the brand jargon)

    Level 3 Pressure Support

    PB 7200 Cannot adjust rise time (limit variable)

    Cannot adjust cycle threshold (cyclevariable)

    Servo-i Adjustable rise time (limit variable)

    Adjustable cycle threshold (cycle variable)

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    ResourcesResources Get the book

    college level textbook

    300 pages

    www.aarc.org/store Training Software

    www.VentWorld.com

    www.Amazon.com

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    Too Complicated?Too Complicated?

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    Final ThoughtFinal Thought If you explain something so

    simply that even a fool can

    understand it, then only a

    fool will understand it."

    FP Primiano Jr