1 Fudemberg SJ, Myers JS, Katz LJ: Trabecular Meshwork Tissue Examination with Scanning Electron Microscopy: A Comparison of Micropulse Diode Laser (MLT), Selective Laser (SLT), and Argon Laser (ALT) Trabeculoplasty in Human Cadaver Tissue. Invest. Ophthalmol. Vis. Sci. 2008;49(5):ARVO E-Abstract 1236.

MicroPulse® Laser Trabeculoplasty (MLT)

“MLT is versatile in a variety of ways: for patients just starting therapy, replacing an eye drop, as an adjunct to an eye drop or to keep them away from incisional surgery.”

Nathan Radcliffe, MDNew York Eye Surgery Center

“MLT is both safe and durable. This therapy can be considered a first-line treatment for glaucoma patients, as well as patients who haven’t seen significant effects from medications.”

Iqbal (Ike) Ahmed, MD, FRCSCUniversity of Toronto

©2014 IRIDEX Corporation. All rights reserved. E0027 2/2014

™

MLT - Meshwork remains intact without the signs of tissue damage while still as effective as ALT & SLT1

ALT - CW laser exposures can cause high thermal rise resulting in tissue damage1

One Year IOP ResultsLong-Term Multi-Center Data using 1000 mW

Pre-op ≥ 21 mmHg

Ike Ahmed, MD, FRCSC, University of Toronto, Toronto, CanadaDavid Gossage, DO, FAOCO, FAAO , Gossage Eye Institute, Hillsdale, MINathan Radcliffe, MD , Weill Cornell Medical College, New York, NYSteven Vold, MD , Vold Vision, LLC Fayetteville, AR

# of pts 40 34 34 13 10

24.6% 28.3% 28.3%

24.4 ± 3.6

18.4 ± 2.9 18.5 ± 0.9

0.0

5.0

10.0

15.0

20.0

25.0

30.0

Baseline 1 month 3-4 months 6 months 1 year

IOP

mm

Hg

24.2%

17.5 ± 2.9 17.5 ± 3.6

1 Year IOP Results

Meds 3.0 2.8 (NS)

~ 6 mmHg drop~ 25% IOP reduction

The 1 year results show approximately 6 mm Hg drop in IOP equating to a 25% reduction.

Iqbal (Ike) Ahmed, MD, FRCSC, University of Toronto, Canada | David Gossage, DO, FAOCO, FAAO, Gossage Eye Institute, Hillsdale, MI Nathan Radcliffe, MD, New York Eye Surgery Center, New York, NY | Steven Vold, MD, Vold Vision LLC, Fayetteville, AR

Evidence of Dose Response

• Rotatable indexing ring allows for confluent laser treatment without removing the MLT lens from the eye

• Tactile positions of the indexing ring are aligned to clock hours, thus facilitating memory of approximate location of previous subthreshold laser spots in the case the patient blinks

• Visible white reference guide assists placement of 10 confluent laser treatments per clock hour

MLT Lens

©2014 IRIDEX. Printed in U.S.A. LT0609 10/2014

Specifications are subject to change without notice. IRIDEX, IRIDEX logo and MicroPulse are registered trademarks and TxCell and IQ 532 are trademarks of IRIDEX Corporation. All other trademarks are the property of their respective owners.

Products are covered by one or more of the following U.S. patents: 5,511,085; 5,982,789; 6,327,291; 6,540,391; 6,733,490; 7,766,904; 7,771,417; 7,909,816; 5,997,498; 6,073,759; 6,092,898; 6,217,594; 6,494,314; 6,585,679; 6,726,666; 6,800,076; 6,866,142; 7,537,593; 8,177,777; 783783; 69530497.6; KR 348012; 0904615; 69706541.3; CA 2331837; AU 759193; JP 4149670; EP 1009684; CA 2286002; JP 449444; JP 4570696; JP 4819754; JP 5123973; JP 5133069.

Other U.S. and international patents pending.

LASER RADIATIONAVOID EYE OR SKIN EXPOSURE TODIRECT OR SCATTERED RADIATION

CLASS 4 LASER PRODUCTCLASS 2 LASER PRODUCT

(IEC 60825-1:2007)

λ = 532 nm PO = 5 Wλ = 635 nm PO = 1 mW

Emergo EuropeMolenstraat 15, 2513 BH, The Hague, The Netherlands, Tel.: (31) (0) 70 345-8570, Fax: (31) (0) 70 346-7299EC REP

The data shows the greatest IOP reduction was experienced by performing MLT at 1000 mW.

David Gossage, DO, FAOCO, FAAO , Gossage Eye Institute, Hillsdale, MI

% IOP Reduction

05

1015202530

300mW700mW

1000mW

1 Month

4 Months

12 months

David Gossage, DO, FAOCO, FAAO, Gossage Eye Institute, Hillsdale, MI

% IO

P R

educ

tion