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FINAL EXAM DECEMBER 2011 NATIONALBOARD OF EXAMINATIONS MICROBIOLOGY PAPER. I Time :3 hours Max.Marks : 100 Attemptall questionsin order. Eachquestioncarries 10 marks. a. Enumerate the causative agents of non-gonococcal urethritis. b. Whatclinical specimens are collected? c. Discuss the laboratory diagnosis of non-gonococcal urethritis. a. Write briefly about the infections caused by Legionella pneumophila. b. Enumerate the determinants of its pathogenicity. c. Describe about its laboratory diagnosis in brief. a. Compare the new methods of detecting mycobacterial species in clinical specimens. b. Describe the clinical significance of non-tuberculous mycobacteria. a. Describe the pathogenesis of diarrhoegenic Escherichia colistrains. b. Describe laboratory diagnosis of these Escherichia colistrains. Write about the pathogenesis and laboratory diagnosis of Clostridium difficile infection. Writedifferences between Acti nomycetoma and Eu mycetoma. Enumerate the causative agents of Eumycetoma Write briefly about the laboratory diagnosis of Eumycetoma. Briefly discuss Phaeohyphomycosis Discuss its clinical manifestations. Discuss its laboratory diagnosis. 8. Write briefly on Aspergillosis under following headings: a. lts causative agents b. lts clinicalforms c. Laboratory diagnosis 9. Discuss briefly Pneumocystis under following headings: a. lts clinical manifestations b. Lifecycle of P. jirovecii c. Laboratory diagnosis of Pneumocystis 10. Enumerate the agents and vectorsof Rickettsial diseases. Briefly describe their epidemiology and laboratory diagnosis. POSSESSION/USE OF CELL PHONESORANYSUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE Mf cRo/Dl11l18ll 3 1 6 3 2 5 6 4 1. 2. 5 5 5+5 3. 4. 5. 6. 2 4 4 4 2 4 3 4 3 a. b. c. a. b. c. 7. 3 4 3 5+5 THE EXAMINATION HALL

Transcript of MICROBIOLOGY PAPER. I - natboard.edu.in · FINAL EXAM DECEMBER 2011 NATIONAL BOARD OF EXAMINATIONS...

FINAL EXAMDECEMBER 2011

NATIONAL BOARD OF EXAMINATIONS

MICROBIOLOGY

PAPER. ITime :3 hoursMax. Marks : 100Attempt all questions in order.Each question carries 10 marks.

a. Enumerate the causative agents of non-gonococcal urethritis.b. What clinical specimens are collected?c. Discuss the laboratory diagnosis of non-gonococcal urethritis.

a. Write briefly about the infections caused by Legionellapneumophila.

b. Enumerate the determinants of its pathogenicity.c. Describe about its laboratory diagnosis in brief.

a. Compare the new methods of detecting mycobacterial species inclinical specimens.

b. Describe the clinical significance of non-tuberculous mycobacteria.

a. Describe the pathogenesis of diarrhoegenic Escherichia coli strains.b. Describe laboratory diagnosis of these Escherichia coli strains.

Write about the pathogenesis and laboratory diagnosis of Clostridiumdifficile infection.

Write differences between Acti nomycetoma and Eu mycetoma.Enumerate the causative agents of EumycetomaWrite briefly about the laboratory diagnosis of Eumycetoma.

Briefly discuss PhaeohyphomycosisDiscuss its clinical manifestations.Discuss its laboratory diagnosis.

8. Write briefly on Aspergillosis under following headings:a. lts causative agentsb. lts clinicalformsc. Laboratory diagnosis

9. Discuss briefly Pneumocystis under following headings:a. lts clinical manifestationsb. Life cycle of P. jiroveciic. Laboratory diagnosis of Pneumocystis

10. Enumerate the agents and vectors of Rickettsial diseases. Brieflydescribe their epidemiology and laboratory diagnosis.

POSSESSION/USE OF CELL PHONES ORANYSUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE

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THE EXAMINATION HALL

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FINAL EXAMDECEMBER 2011

NATIONAL BOARD OF EXAMINATIONS

Time : 3 hoursMax. Marks : 100

MICROBIOLOGY

PAPER. IIMfcRo/D111t18t,l

Attempt all questions in order.Each question carries 10 marks.

Classify trematodes on the basis of their habitat.Give general features of blood flukes.

Enumerate intestinal acid fast protozoa.Give laboratory diagnosis of Cryptosporidios,is.

List the sporozoa that cause human infection.Write about host immunity and prophylaxis of malaria.List the laboratory tests used for diagnosis of cerebralmalaria.

4. a. List the agents causing primary amoebicmeningoencephalitis.

b. Write about its transmission and pathogenicity.c. Discuss its laboratory diagnosis.

a. Classify nematodes on the basis of habitat.b. Discuss life cycle, pathogenicity and laboratory diagnosis of

Strongyloides stercoralis.

a. Define prions.b. Enumerate diseases produced by prions.c. Give characteristics of prion diseases.

7. Enumerate the various immunological abnormalities seen in HIV- infections.

a. Briefly discuss properties and pathogenesis of Delta agents.b. Outline its laboratory diagnosis in brief.

a. Define arboviruses.b. Enumerate arboviruses prevalent in lndia.c. Briefly write on arboviruses transmitted by Culex mosquitoes

in India.

10. a. Outline the pathogenesis of Polio viruses.b. Differentiate vaccine strain from wild strain.c. Briefly write on C and D antigens.

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FINAL EXAM-DECEMBER 2011

MICROBIOLOGY

. PAPER. IIIT ime :3 hoursMax. Marks : 100

Attempt all questions in order.Each question carries 10 marks.

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NATIONAL BOARD OF EXAMINATIONS

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a. Enumerate the causes of chronic meningitis in India.b. Write about its laboratory diagnosis, including the recent

advances.

a. Enumerate the common causes of bacterial food poisoning.b. Write about pathogenesis and laboratory diagnosis of food

poisoning.

What is "atypical" pneumonia?List its common causes.Describe the approach to its laboratory diagnosis.

List water borne pathogenswrite about various methods for bacteriological examinationof water.

5. Describe the prevention and control of influenza virus in humans,

What is pulse polio immunization?Comment on reasons of non-eradication of poliomyelitis.Discuss strategies to overcome it.

Write about importance of hand washing in hospital practice.When should a health care worker decontaminate hands?Describe the steps of hand hygiene.

List various immuno-enzymatic reactions.Describe them with suitable examples of applications.

List the hospital strains of staphylococcus.Describe their role in hospital infection,

Define MlC.What are MIC 50 and MIC 90?Describe different methods of MIC determination along withtheir advantages and disadvantages.

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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDETHE EXAMINATION HALL

FINAL EXAMDECEMBER 2011

Time :3 hoursMax. Marks : 100

Attempt all questions in order.Each question carries 10 marks.

NATIONAL BOARD OF EXAMINATIONS

MICROBIOLOGYPAPER. M

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What is flexible genetic pool in microbes?Describe their significance and applications.

Define immunological tolerance and autoimmunity.Discuss establishment and maintenance of tolerance.Enumerate proposed mechanisms fdr induction ofautoimmunity.

What are hypersensitivity reactions? Classify them.Tabulate the cells involved, mechanism of hypersensitivityand give examples of each type.

4. a. Enumerate the different types of microscopes used inMicrobiology.

b. Write their principles.c. Discuss electron microscope in detail.

Discuss Quality Assurance in Microbiology laboratory.

a. Enumerate the different laboratory acquired infections inMicrobiology.

b. Discuss routes of infection.c. Discuss organization of Biosafety levels.

4. Define immuno-diffusion. Write about its advantages'b. Enumerate various types of immuno-diffusion; give theprinciple of each with one example of its application.

a. Discuss briefly bacterial metabolism.b. Briefly write on :-

(i) Oxidation(ii) Fermentationiii) Redox potential

a. Define mutation.b. Discuss briefly different types of mutation.c. How would you demonstrate mutations?

10. Discuss the role of normal microbialflora in health and disease.

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POSSESSION/USE OF CELL PHONES OR ANY SACH ELECTRONIC GADGETS IS NOT PERMITTED INSIDETHE EXAMINATION HALL