Methylation Diagram
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Arginine Ornithine Urea ammonia NOS Citrulline + NO Urea Neuronal Damage Microglial Activation Oxidative-Inflammatory Disease Peroxynitrate Super Oxide 2 BH4 1 BH4 0 BH4 BH4 BH2 Tryptophan Tyrosine Serotonin Dopamine DHPR Neurotransmitter MAO A MAO B COMT HIAA HVA NorEp MAO B COMT VMA MTHFR THF 5 Methyl THF Methionine Homocysteine Thymidine synthesis dUMP MSR MS SAHH BHMT CBS Folate Cycle Methionine Cycle TMG DMG SAMe SAH Methylation DNA, RNA, Protein, Lipids Guanido Ac Creatine Creatinine adenosine Cystathionine B6, P5P Ammonia Cysteine + α KG Sulfite Glutathione Taurine Sulfate Moly SUOX Transsulfuration Cobalamin Cycle MAT Adapted from Dr. Amy Yasko
description
Methylation
Transcript of Methylation Diagram
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2012 The Institute for Functional Medicine
Arginine
Ornithine
Urea ammonia
NOS
Citrulline + NO
Urea
Neuronal Damage
Microglial Activation
Oxidative-Inflammatory Disease
Peroxynitrate
Super Oxide
2 B
H4
1
BH
4
0 B
H4
BH4
BH2
Tryptophan Tyrosine
Serotonin Dopamine
DHPR
Neurotransmitter
MAO A MAO B
COMT HIAA
HVA
NorEp
MAO B
COMT
VMA
MTHFR
THF
5 Methyl THF
Methionine
Homocysteine
Thymidine synthesis
dUMP
MSR
MS
SAHH
BHMT
CBS
Folate Cycle Methionine Cycle
TMG
DMG
SAMe
SAH
Methylation
DNA, RNA, Protein, Lipids
Guanido Ac
Creatine
Creatinine
adenosine
Cystathionine
B6, P5P
Ammonia
Cysteine + KG
Sulfite Glutathione Taurine
Sulfate
Moly SUOX
Transsulfuration
Cobalamin Cycle
MAT
Adapted from Dr. Amy Yasko
