Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013
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Transcript of Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013
North Carolina’s Life Sciences Cluster
Impact of the North Carolina Biotechnology Center
21 August 2013
Mark Lombard, MBA Program Director, Bioscience Industrial Development North Carolina Biotechnology Center
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
North Carolina, USA
• Place – 3 major research universities in a 30 mile radius – Ecosystem of supportive organizations, risk capital,
entrepreneurial culture
• People – Collaboration among visionary business, academia, gov’t leaders – Attract and retain scientific and business talent
• Programs – Company creation, attraction, retention, expansion programs – Innovative workforce development programs
• Patience – North Carolina Biotechnology Center: 30 years – Research Triangle Park: 50+ years
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Life Sciences in North Carolina
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Brazil and North Carolina
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Brazil and North Carolina
Sao Paulo (2012) • Population: 41,901,219
• Density: 170/km2
• GDP (2010) – US$615M
– US$15,322 per capita
• Machinery, auto and aviation, services, finance, textiles, oranges, sugar cane, coffee, life sciences
North Carolina (2012) • Population: 9,752,073
• Density: 83/km2
• GDP (2010) – $407M
– $42,884 per capita
• Cotton, tobacco, hogs, chickens, textiles, furniture
• Finance, advanced mfg, IT, life sciences
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Sao Paulo and North Carolina
BIOTECHNOLOGY IN NORTH CAROLINA
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Global Challenges
• Human/Animal health
• Food availability & security
• Energy
• Environmental sustainability
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Biotechnology: Heal, Fuel, Feed the World
Biotech in NC – Large and Diverse
• 3rd Largest Life Science Cluster in the US
– Medical Devices & Diagnostics
– Contract Research & Manufacturing
– Biopharma
– Agricultural Biotech
58%21%
21%
560+ Companies60,000+ Employees
R&D
CRO/Testing
Mfg/Prod
Biotech in NC – Fastest Growing
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Spe
cial
izat
ion
Growth Rate
• Average salary - $78,348
– Nearly double the state’s private sector average
• 3.6 additional jobs for each biotech job
• 226,000 total jobs
Biotech in NC – High Impact Jobs
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
• Direct biotechnology sector revenues $41.2 billion
• Employee compensation $12.7 billion
• State and local revenues $1.92 billion
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Biotech in NC – Annual Economic Impact
THE NORTH CAROLINA BIOTECHNOLOGY CENTER
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
To provide long-term economic and societal benefits to North Carolina through support of biotech research, business, education and strategic policy statewide.
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Mission
• State-funded, private, non-profit corporation
• Portfolio of programs – Research
– Business
– Education
– Economic Development
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – What We Do
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
• Grant funding for:
– New research ideas
– Build capacity – equipment/faculty
– University/Company research projects
• $98 million granted
• $4 to $70 leveraged
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Research Support
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
Company Creation and Growth: NCBiotech Loan Program
• $50K - $250K low interest loans • ROI = $117 per $1 loaned
NORTH CAROLINA BIOTECHNOLOGY CENTER
Notable Recent Successes
$96 million acquisition
$25 million IPO
BioKier $1.7 million seed financing
Up to $1.6 million grant
Advanced Liquid Logic Microfluidics Lab Instruments
• 2003: $50,000 CFG
• Aug-2004: Company founded
• May-2005: $15,000 BDL – 1 employee
• Sep-2005: $72,600 SBR – 3 employees
• Sep-2006: $160,000 SGL – 6 employees
• Jun-2009: $220,500 SGL – 24 employees
• 2011: Launched products for newborn screening, genomic sample prep
• 2011-2013: NCBiotech VC events in Palo Alto, Boston, NYC
• Aug-2012 : $100,000 IFP
• Jul-2013 : $96M acquisition by Illumina – 80 employees
– All loans repaid in full + interest and warrants
– >$50 million follow-on funding before acquisition
• Introductions to bankers and investors, NCBIP, Library, Jobs Board, NCBiotech Partnering 2011-2013, Corporate Communications
Heat Biologics Cell-based Cancer Immunotherapy
• 2008: Company founded in FL
• Aug-2011: Recruited to NC
• 2011-2012: Assistance with investor pitch
• 2011-2012: NCBiotech VC events in Palo Alto, Boston
• Nov-2011: $225,000 SGL - 2 NC employees – Repaid in full with interest + warrants
• Apr-2012: Industrial Internship Program
• Apr-2013: $5 million VC round
• Jul-2013: $25 million IPO – NASDAQ:HTBX – 5 NC employees
• Investor introductions, partner introductions, foundation introductions, BATON, Library, Corporate Communications, NCBiotech Partnering 2012, BIO Pavilion
BioKier “Medicinalize” Gastric Bypass for Diabetes
• Nov-2008: Company founded
• Oct-2010: Emerging Company Preview
• Oct-2010: $250,000 SRL – 2 employees
• Oct-2012: Pitch Scrub
• Nov-2012: SEBIO Presentation
• Apr-2013: Southeast Venture Philanthropy Summit
• May-2013: $250,000 SGL – 3.5 employees
• Jul-2013: $1.7 million Broadview Ventures, AHA
• Investor introductions, NCBIP, Corporate Communications, Library, NCBiotech Partnering 2011-2013, LSBDP, Biotech Forums
Eboo Pharmaceuticals Opioid Modulators for CNS Diseases
• Feb-2012: Company founded
• May-2012: $30,000 CIL – 2 NC employees
• Jun-2012: Introduction to Biogen IDEC
• Jul-2012: SBIR letter of support, recommended MJFF
• Oct-2012: Introductions to CEO candidates
• Nov-2012: Advice on business plan, investor pitch
• Dec-2012: Emerging Company Preview
• Feb-2013: Facilitated meeting with Eli Lilly
• Apr-2013: Southeast Venture Philanthropy Summit
• Jun-2013: Up to $1.6M grant Michael J. Fox Foundation
• BATON, Corporate Communications, Library
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Products, Companies and Jobs
Education, Networking and Other Programs
Statewide Econ Devel
Statewide Offices
– Research Triangle Park – Eastern (Greenville) – Southeastern
(Wilmington)
– Western (Asheville) – Greater Charlotte – Piedmont Triad
(Winston-Salem)
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Since July 2010 • 21 projects • 1,754 employees
Ripple effects: • 7,803 total jobs • $490 million in payroll • $59 million in state and
local revenues • $2.0B in economic activity
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development
• BIO 2004 in San Francisco – Chiron
• 2006: project announced • 2009: plant opens • 2012: production begins • 2012: $36M expansion • 2013: $60M expansion • Today: >$1B invested, 700
employees, will grow to 1000
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development Novartis Vaccines
• Early 2010: introduced by Canadian Consulate
• Mid 2010: DARPA, ARE
• Late 2010: construction begins
• Mid 2012: 10M flu doses in one month
• 2013: Acquired by Mitsubsihi in a $357M deal
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development Medicago
• 2011: Sequenom (molecular diagnostics) – 242 jobs, $19M investment
• 2012: Aerocrine (asthma diagnostics) – 45 jobs
• 2013: bioMerieux: (in vitro diagnostics) – 44 jobs, $44M investment
• 2013: Syngenta (agricultural biotech) – 150 jobs, $94M investment
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development Recent Announcements
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
• 1900+ teachers trained
• 50,000 students reached each year
• $7M in grants for lab equipment & new courses
• 8,000+ BioWork manuals distributed to colleges
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Workforce and Education
• Industry-driven biopharma manufacturing training and education
• Emerging and existing labor
• BTEC
– 82,500 SF; $60M
– $12.5M equipment
– cGMP pilot plant
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Biomanufacturing Workforce NCBIOIMPACT
• High-profile conferences
• Hamner Conference Center – 30,000 guests annually
• Networking groups – More than 3,000 attendees
• Biotech Library
• NCBiotech Job Network
• And much more
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Networking and Community
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Looking Ahead
Supportive Ecosystem
• Place – 3 major research universities in a 30 mile radius – Ecosystem of supportive organizations, risk capital,
entrepreneurial culture
• People – Collaboration among visionary business, academia, gov’t leaders – Attract and retain scientific and business talent
• Programs – Company creation, attraction, retention, expansion – Innovative workforce development programs
• Patience – North Carolina Biotechnology Center: 30 years – Research Triangle Park: 50+ years
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Life Sciences in North Carolina
Thank You
Mark Lombard Program Director, Bioscience Industrial Development North Carolina Biotechnology Center