MALIGNANT NEOPLASMS OFNASAL CAVITY

BY: MOHIT KADYANROLL NO: 26

TUMORS OF NASAL CAVITY

CARCINOMA OF NASAL CAVITY -SQUAMOUS CELL CARCINOMA -ADENOCARCINOMA

MALIGNANT MELANOMAOLFACTORY NEUROBLASTOMALYMPHOMAPLASMACYTOMAOTHERS SARCOMA AND HAEMANGIOPERICYTOMA

1. SQUAMOUS CELL CARCINOMA• It is the most common variety , seen in about 80% of cases• Above 50 years of age • It may arise from -vestibule, -anterior part of nasal septum or -lateral wall of nasal cavity.• Vestibular: arises from lateral wall of vestibule and extends into

collumela , nasal floor, and upper lip .• Septal: arises from mucocutaneous junction causing burning and

sore nose . It is termed as “nose-picker’s cancer’’.

• Lateral wall: most common site , extends into ethmoid or maxillary sinus , presents as polypoidal mass in lateral wall of nose

• Vestibular spreads to parotid nodes while septal and lateral wall neoplasms show low metastatic tendency.

Treatment: Combination of radiotherapy and surgery

Metastasis:

Adenocarcinoma and adenoid cystic carcinoma.

•They arise from the glands of mucous membranes , mostly involve upper part of the lateral wall of nasal

cavity.

2. Malignant melanoma

• Usually seen in persons about 50 yrs of age. • Cell of origion is MELANOCYTE• It presents as slaty-gray or bluish-black polypoid

mass.• Anterior part is most common site followed by

middle and inferior turbinate.• Amelanotic are the non-pigmented varieties

METASTASIS:• Tumour spreads to cervical nodes by blood

and lymphatic route

TREATMENT: • Surgical incision is the treatment , radiotherapy and

chemotherapy are avoided as it supresses immunity

3. Olfactory neuroblastoma

• Tumour of olfactory placode can be seen in any age group.

• Cherry red , polypoidal mass in upper nasal cavity.

• Bleeds on biopsy as it is highly vascular.

Metastasis:• Lymph node or systemic metastasis can occur

Treatment:• Can be cured by radiotherapy alone• Surgical excision is followed presently along with radiation• Craniofacial resection may be required for tumors of

cribriform plate.

4.Haemangiopericytoma

• Rare tumour of vascular origin seen in 60-70 yrs of age.

• Cell of origion is ‘’pericyte’’ which surround capillaries

• Patients present with epistaxis• Tumour bleeds on biopsy• Treatment is surgical excision and radiotherapy is

tried for recurrent and inoperable cases.

5. Plasmocytoma

• Affects males over 40 yrs of age• Solitary plasmocytoma without any osseous

disease can be seen in the nasal cavity • Treatment is by radiation followed 3 months

later by surgery , if regression doesn’t occur• long term follow up is advised to exclude

development of Multiple myeloma.

6. Sarcomas

• Osteogenic sarcoma , chondrosarcoma, rhabdomyosarcoma , angiosarcoma , malignant histiocytoma are other rare tumours affecting the nose.

7. lymphoma

• Rarely a non-hodgkin lymphoma presents on septum of nose.

Thank You