Male Reproductive System - Histopathology Service · 2014. 1. 16. · Male Reproductive Hormones....
Transcript of Male Reproductive System - Histopathology Service · 2014. 1. 16. · Male Reproductive Hormones....
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Chapter 17
Male Reproductive System
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Each testis contains about 250 meters of seminiferous tubule
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• Testes: produce sperm (spermatogenesis)
– Production Site: seminiferous tubules
– About 250 meters of tubule/testis
– 100 – 300 million sperm/day produced
• Testes also produce male hormones
(testosterone)
Two Major Functions of Testes
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Delivery of Sperm to the Egg
• The duct system stores and transports sperm
– Delivery through reproductive tubules: epididymis
vas deferens urethra penis
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Delivery of Sperm to the Egg
• The seminal vesicles and prostate gland (accessory glands) produce most of the volume of semen
• The penis transfers
sperm to the female
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The organ where sperm are
produced is
A. Testes
B. Prostate gland
C. Seminal vesicle
D. Penis
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• Sperm development involves reduction in the
number of chromosomes and in the structure
of sperm cells
• Several cell divisions of mitosis and meiosis
–Purpose: produce a large number (> 100
million/day) of sperm with half the number of
chromosomes of somatic cells (haploid)
Sperm Production
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(Leydig cells)
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The organ where sperm are
produced is
A. Prostate gland
B. Testes
C. Seminal vesicle
D. Ovary
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Mature sperm contain:
A. 46 chromosomes
B. The same number of chromosomes
as the father
C. 23 chromosomes
D. Half the number of chromosomes as
the father
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• Hormones:– Testosterone• Source: Interstitial (Leydig) cells in testes
– LH: stimulates production of testosterone in interstitial (Leydig) cells
– FSH: enhances sperm formation by Sertoli cells
Male Reproductive Hormones
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Testosterone secretion is regulated by a negative
feedback loop (see in class worksheet)
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The Male Reproductive System
• The hypothalamus (neurosecretory cells)
releases gonadotropin-releasing hormone
(GnRH)
• GnRH stimulates the anterior pituitary
gland to secrete luteinizing hormone
(LH)
• LH stimulates the production of
testosterone by the testes
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The rising testosterone level inhibits the
release of GnRH to complete the loop
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Actions of Testosterone on Target
Tissues
• Actions of Testosterone
– Controls growth and function of male
reproductive tissues (e.g., prostate &
seminal vesicles)
– Secondary sexual characteristics: muscle,
auxiliary hair, larynx, balding pattern
– Stimulates aggression and sexual behavior
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Testosterone has effects on:
A. Male secondary sexual
characteristics, e.g., muscle, beard
growth
B. Prostate gland
C. Sex drive
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The function of the prostate gland is to:
A. Produce sperm
B. Produce testosterone
C. Produce secretions (semen) that
make sperm mobile
D. Store sperm