Male Reproductive System - Histopathology Service · 2014. 1. 16. · Male Reproductive Hormones....

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Chapter 17 Male Reproductive System

Transcript of Male Reproductive System - Histopathology Service · 2014. 1. 16. · Male Reproductive Hormones....

  • Chapter 17

    Male Reproductive System

  • Each testis contains about 250 meters of seminiferous tubule

  • • Testes: produce sperm (spermatogenesis)

    – Production Site: seminiferous tubules

    – About 250 meters of tubule/testis

    – 100 – 300 million sperm/day produced

    • Testes also produce male hormones

    (testosterone)

    Two Major Functions of Testes

  • Delivery of Sperm to the Egg

    • The duct system stores and transports sperm

    – Delivery through reproductive tubules: epididymis

    vas deferens urethra penis

  • Delivery of Sperm to the Egg

    • The seminal vesicles and prostate gland (accessory glands) produce most of the volume of semen

    • The penis transfers

    sperm to the female

  • The organ where sperm are

    produced is

    A. Testes

    B. Prostate gland

    C. Seminal vesicle

    D. Penis

  • • Sperm development involves reduction in the

    number of chromosomes and in the structure

    of sperm cells

    • Several cell divisions of mitosis and meiosis

    –Purpose: produce a large number (> 100

    million/day) of sperm with half the number of

    chromosomes of somatic cells (haploid)

    Sperm Production

  • (Leydig cells)

  • The organ where sperm are

    produced is

    A. Prostate gland

    B. Testes

    C. Seminal vesicle

    D. Ovary

  • Mature sperm contain:

    A. 46 chromosomes

    B. The same number of chromosomes

    as the father

    C. 23 chromosomes

    D. Half the number of chromosomes as

    the father

  • • Hormones:– Testosterone• Source: Interstitial (Leydig) cells in testes

    – LH: stimulates production of testosterone in interstitial (Leydig) cells

    – FSH: enhances sperm formation by Sertoli cells

    Male Reproductive Hormones

  • Testosterone secretion is regulated by a negative

    feedback loop (see in class worksheet)

  • The Male Reproductive System

    • The hypothalamus (neurosecretory cells)

    releases gonadotropin-releasing hormone

    (GnRH)

    • GnRH stimulates the anterior pituitary

    gland to secrete luteinizing hormone

    (LH)

    • LH stimulates the production of

    testosterone by the testes

  • The rising testosterone level inhibits the

    release of GnRH to complete the loop

  • Actions of Testosterone on Target

    Tissues

    • Actions of Testosterone

    – Controls growth and function of male

    reproductive tissues (e.g., prostate &

    seminal vesicles)

    – Secondary sexual characteristics: muscle,

    auxiliary hair, larynx, balding pattern

    – Stimulates aggression and sexual behavior

  • Testosterone has effects on:

    A. Male secondary sexual

    characteristics, e.g., muscle, beard

    growth

    B. Prostate gland

    C. Sex drive

  • The function of the prostate gland is to:

    A. Produce sperm

    B. Produce testosterone

    C. Produce secretions (semen) that

    make sperm mobile

    D. Store sperm