LuCID Clinical Trial - Owlstone Medical · lucid clinical trial early detection of lung cancer this...
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limonene isoprene methanol acetonitrile acetone acetamide 2-butanone acetophenone "OWLSTONE MEDICAL HAS DEVELOPED THE BREATH BIOPSY PLATFORM WHICH ENABLES RELIABLE COLLECTION AND ANALYSIS OF VOLATILE ORGANIC COMPOUNDS IN BREATH" LuCID Clinical Trial Early Detection of Lung Cancer THIS YEAR 2.5 Billion WILL COST THE NATIONAL HEALTH SERVICE LUNG CANCER THIS YEAR 44 , 000 PEOPLE WILL BE 35 , 200 WILL DIE IN THE UK LUNG CANCER AND DIAGNOSED WITH NHS IF DETECTED AT STAGE IV STAGE I 75 PEOPLE WILL SURVIVE LUNG CANCER 5 OUT OF 100 UNFORTUNATELY PATIENTS 14.5 % ONLY OF ARE DETECTED AT STAGE I THERE IS AN URGENT AND GROWING NEED TO IMPROVE EARLY DIAGNOSIS IN LUNG CANCER EVERY TIME WE BREATHE OUT THERE OVER A THOUSAND OF CHEMICALS ON OUR BREATH SOME OF THESE CHEMICALS ARE ‘TELL TALE’ MARKERS OF DISEASE 20 2 9 14 21 13 12 19 10 11 8 1 16 18 7 6 17 5 25 26 24 23 22 15 4 3 OUR MISSION 100,000 AND SAVE 1.5 $ BILLION TO SAVE LIVES HEALTHCARE COSTS THE BREATH BIOPSY PLATFORM IS BEING USED IN THE WORLD'S LARGEST BREATH- BASED CLINICAL TRIALS THE LuCID TRIAL WILL RECRUIT UP TO 4,000 PATIENTS ACROSS MULTIPLE CLINICAL SITES IN EUROPE, AND IS EVALUATING THE UTILITY OF BREATH BIOMARKERS IN DETECTION OF LUNG CANCER QUICK, NON-INVASIVE AND EASY TO USE, IT CAN BE USED IN A DOCTOR’S OFFICE TO HELP DETERMINE IF HIGH RISK PATIENTS SHOULD BE REFERRED FOR TESTING IN HOSPITAL
Transcript of LuCID Clinical Trial - Owlstone Medical · lucid clinical trial early detection of lung cancer this...
limonene
isoprene
methanolacetonitrile
acetone
acetamide
2-butanone
acetophenone
"OWLSTONE MEDICAL HAS DEVELOPED THE BREATH BIOPSY PLATFORM WHICH ENABLES RELIABLE COLLECTION AND ANALYSIS OF VOLATILE ORGANIC COMPOUNDS IN BREATH"
LuCID Clinical TrialEarly Detection of Lung Cancer
THIS YEAR
2.5Billion
WILL COST THENATIONALHEALTHSERVICE
LUNGCANCER
THIS YEAR44,000PEOPLE WILL BE
35,200WILL DIE IN THE UK
LUNG CANCER ANDDIAGNOSED WITH
NHS
IF DETECTED AT STAGE IVSTAGE I
75PEOPLE WILLSURVIVELUNG CANCER
5OUT
OF 100
UNFORTUNATELY
PATIENTS
14.5%
ONLY
OF
ARE DETECTED AT STAGE I
THERE IS AN URGENT AND GROWING NEED
TO IMPROVE EARLY DIAGNOSISIN LUNG CANCER
EVERY TIME WE BREATHE OUTTHERE OVER A THOUSAND OF
CHEMICALS ON OUR BREATH
SOME OF THESE CHEMICALS ARE‘TELL TALE’ MARKERS OF DISEASE
20
2
9
14
21
13
1219
10
11
8
1
1618
76
17
5
25
26
24
23
2215
43
OUR
MISSION100,000AND SAVE
1.5$ BILLION
TO SAVE
LIVES HEALTHCARE COSTS
THE BREATH BIOPSYPLATFORM IS BEING USED INTHE WORLD'S LARGEST BREATH-
BASED CLINICAL TRIALSTHE LuCID TRIAL WILL RECRUIT UP TO
4,000 PATIENTS ACROSS MULTIPLECLINICAL SITES IN EUROPE, AND ISEVALUATING THE UTILITY OF BREATH
BIOMARKERS IN DETECTION OF
LUNG CANCER
QUICK, NON-INVASIVE AND EASY TO USE,IT CAN BE USED IN A DOCTOR’S OFFICETO HELP DETERMINE IF HIGH RISKPATIENTS SHOULD BE REFERRED FOR
TESTING IN HOSPITAL
The LuCID Trial
How Does Breath Biopsy Work?
owlstonemedical.com/lucidOwlstone Medical Ltd, 183 Cambridge Science Park, Milton Road, Cambridge, CB4 0GJ, UK
Company Number 04955647 | VAT Number 260449214
Owlstone Medical's Products and Services are for research use only.Not for use in diagnostic procedures. O
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Signal
THRESHOLD
CONTROL DISEASE
1 minSample whole body
10 minsCapture even low levelVOC biomarkers
=1 complete
blood circulation
1 min
SCREENING
THE CHEMICAL MARKERS OF LUNG CANCER ARE PRESENT EVEN IN THE EARLIEST STAGES OF THE DISEASE. FOR THE FIRST TIME THERE IS THE REAL POTENTIAL FOR ROUTINE SCREENING AND IMPROVED RATES OF EARLY DIAGNOSIS, TRANSFORMING THE LIVES OF COUNTLESS PATIENTS AND THEIR FAMILIES.
Rapid transfer of VOCsfrom blood to breath
Collect and pre-concentrate VOCs in Breath Biopsy Cartridges
EVERY MINUTE , ALL THEBLOOD IN YOUR BODY PASSESTHROUGH YOUR LUNGS
THIS ALLOWS SAMPLING OFTHE ENTIRE BLOOD VOLUMEIN YOUR BODY
VOLATILE ORGANIC COMPOUNDSFROM YOUR WHOLE BODY CANTHEREFORE BE COLLECTED ANDANALYZED, PROVIDING BOTH LOCALAND SYSTEMIC DISEASE INFORMATION
PATIENTS WITH SUSPECTEDLUNG CANCER GIVE A SAMPLEAT THE SAME TIME AS THEIRHOSPITAL APPOINTMENT
WITH OWLSTONE MEDICAL'SMACHINE LEARNINGALGORITHMS AND BREATH BIOPSY
DIGITAL BIOBANK
ALL PATIENTS HAVE TO DOIS BREATHE THROUGHTHE ReCIVA BREATH SAMPLER
FOR 10 MINUTES
BREATH BIOPSYSAMPLES ARE SENT FOR
ANALYSISIN OWLSTONE MEDICAL’SBREATH BIOPSY LAB
DATA ANALYSIS
