lampiran dapus

DAFTAR PUSTAKA

British Pharmacopea. 2009. British Pharmacopea. British Pharmacopoeia

Commission Office : London Creswell, C. J. 2005..Analisis Spektrum

Senyawa Organik.Institut Teknologi Bandung : Bandung.

Depkes RI. 1979. Farmakope Indonesia Edisi III.Departemen Kesehatan

Republik Indonesia : Jakarta.

Depkes RI. 1995. Farmakope Indonesia Edisi IV.Departemen Kesehatan Republik

Indonesia : Jakarta

Gritter, R.J., Bobbit, G.M., Schwarting, A.E. (1991), Pengantar Kromatografi,

Terjemahan oleh Kosasih Padmawinata, Penerbit ITB, Bandung.

Harmita. 2006. Buku Ajar Analisis Fisikokimia. Departemen Farmasi FMIPA:Jakarta

Roth, Hermann J. 1985. Analisis Farmasi. Gadjah Mada University Press.

Yogyakarta.

Satiadarma, K, Tjahjono, D.H, Kartasasmita, R.E.. 2004. Analisis Farmasi.

Surabaya : Airlangga University Press.

Vandamme , Erik J. 1989. Biotechnology of Vitamins Pigments and Growth

Factor. USA. Elsevier Science Publisher.

LAMPIRAN

1. Data Scanning Absorbansi Piridoksin HCl dengan Internal Standar Thiamin

HCl

Tabel 1.1 Absorbansi Piridoksin HCl 8 ppm dengan Internal Standar Thiamin HCl

8ppm

Parameter

Designation: SPECORD 200 - 222U170Titel internal standar piridoksin - thiaminOperator firdaDate/Time ########Display AbsorbanceCorrection ReferenceSlit 1 nmLamp change at 380 nmMeas. mode Scan ModeRange [nm] 220 - 300Delta lambda[nm] 1Speed [nm/s] 50Cycle Mode Time controlledNumber 3Time [s] 1

----------------------- 5/7/2013 11:05:04 AM Pacific Daylight Time

Measurement

[sec] 0 3 6[nm] 1.[A] 2.[A] 3.[A]

220 0.342 0.3433 0.3422221 0.3354 0.3354 0.3356222 0.3291 0.3287 0.3288223 0.3248 0.3247 0.3247224 0.3234 0.3233 0.3233225 0.3227 0.3226 0.3227226 0.324 0.3233 0.324

227 0.3252 0.3254 0.3256228 0.3292 0.3292 0.3291229 0.3337 0.3337 0.334230 0.3394 0.3396 0.3395231 0.3466 0.3466 0.3466232 0.3547 0.3546 0.3546233 0.3639 0.3634 0.3639234 0.3734 0.3731 0.3731235 0.3836 0.3834 0.3835236 0.4038 0.4039 0.404237 0.4156 0.4149 0.4153238 0.4254 0.4256 0.4253239 0.4355 0.4353 0.4353240 0.444 0.4439 0.4446241 0.4519 0.4518 0.4517242 0.4583 0.4584 0.4588243 0.4647 0.4641 0.4638244 0.468 0.4674 0.4675245 0.4701 0.4696 0.4699246 0.4706 0.4707 0.4713247 0.47 0.4702 0.4699248 0.4672 0.4672 0.4676249 0.4634 0.4634 0.4643250 0.4587 0.4588 0.4586251 0.4476 0.4472 0.448252 0.4415 0.4412 0.4409253 0.4366 0.4357 0.4359254 0.4323 0.4316 0.4318255 0.4295 0.4291 0.4291256 0.4272 0.4268 0.427257 0.4257 0.4252 0.4262258 0.4254 0.425 0.4252259 0.4254 0.425 0.4245260 0.4251 0.4249 0.425261 0.4251 0.4246 0.4252262 0.425 0.4244 0.4248263 0.4248 0.4243 0.4243264 0.424 0.4237 0.4239265 0.423 0.4222 0.4226266 0.4212 0.4209 0.421267 0.417 0.4164 0.4169268 0.4131 0.4127 0.4129269 0.4093 0.4087 0.409270 0.4052 0.4044 0.4055271 0.401 0.4007 0.4012272 0.396 0.3954 0.3965273 0.391 0.391 0.391274 0.3861 0.3859 0.3862

275 0.3806 0.3809 0.381276 0.3759 0.3757 0.3753277 0.3702 0.37 0.3705278 0.3654 0.3642 0.3646279 0.3603 0.3597 0.3598280 0.3561 0.3554 0.3553281 0.3522 0.3518 0.3522282 0.3469 0.3469 0.3471283 0.343 0.3421 0.3432284 0.3411 0.3404 0.3408285 0.3391 0.3388 0.339286 0.3373 0.3366 0.3371287 0.3348 0.3343 0.3347288 0.3322 0.3317 0.3318289 0.329 0.3287 0.3289290 0.3258 0.3255 0.3263291 0.3217 0.3208 0.3217292 0.3162 0.3158 0.3165293 0.311 0.3105 0.3108294 0.3038 0.3029 0.3035295 0.2951 0.2945 0.2952296 0.2864 0.2861 0.2866297 0.267 0.2666 0.2666298 0.2484 0.2482 0.2481299 0.2328 0.232 0.2325300 0.2157 0.2147 0.2151

Tabel 1.2. Absorbansi Piridoksin HCl 9 ppm dengan Internal Standar Thiamin

HCl 8 ppm

Parameter

Designation: SPECORD 200 - 222U170Titel internal standar piridoksin – thiaminOperator firdaDate/Time ########Display AbsorbanceCorrection ReferenceSlit 1 nmLamp change at 380 nmMeas. mode Scan ModeRange [nm] 220 - 300Delta lambda[nm] 1Speed [nm/s] 50Cycle Mode Time controlledNumber 3Time [s] 1


Measurement

[sec] 0 3 6[nm] 1.[A] 2.[A] 3.[A]

220 0.3432 0.3437 0.343221 0.3357 0.3353 0.3357222 0.3278 0.328 0.3282223 0.3229 0.3231 0.323224 0.3205 0.3207 0.3206225 0.3194 0.3199 0.3197226 0.3203 0.3205 0.3203227 0.3221 0.322 0.3221228 0.3257 0.3256 0.3256229 0.3301 0.33 0.3303230 0.3356 0.3358 0.3357231 0.3422 0.3423 0.342232 0.3498 0.3499 0.3502233 0.3588 0.3588 0.3586234 0.3682 0.3679 0.368235 0.3775 0.3778 0.3776236 0.3969 0.3972 0.3972237 0.4079 0.4077 0.4079238 0.4176 0.4173 0.4174239 0.4272 0.4268 0.4268240 0.435 0.435 0.4347241 0.4422 0.4424 0.4428242 0.4484 0.4487 0.4487243 0.4534 0.4535 0.4539244 0.4565 0.457 0.457245 0.459 0.4591 0.4592246 0.4597 0.4597 0.4595247 0.4581 0.4579 0.4584248 0.4558 0.4559 0.456249 0.4521 0.4516 0.4524250 0.4472 0.4472 0.4475251 0.4358 0.4364 0.4364252 0.4305 0.4303 0.4308253 0.4253 0.4256 0.4252254 0.4223 0.4217 0.422255 0.4194 0.4194 0.4196256 0.4176 0.4174 0.4178257 0.4164 0.4168 0.4169258 0.4164 0.4166 0.4168

259 0.417 0.417 0.417260 0.4175 0.4177 0.4177261 0.4176 0.4182 0.4176262 0.418 0.4184 0.4182263 0.4186 0.4184 0.4188264 0.4183 0.4187 0.4187265 0.4179 0.4185 0.418266 0.4175 0.4178 0.4175267 0.4147 0.4148 0.415268 0.4125 0.4124 0.4125269 0.4092 0.4099 0.4096270 0.4065 0.4069 0.407271 0.4043 0.4041 0.4035272 0.4004 0.3997 0.4004273 0.3966 0.3963 0.3974274 0.3929 0.3934 0.3933275 0.3893 0.3889 0.3894276 0.3856 0.3854 0.3853277 0.3822 0.3812 0.382278 0.3785 0.3779 0.3783279 0.3753 0.3751 0.3753280 0.3721 0.3723 0.3724281 0.37 0.3706 0.3705282 0.3682 0.3678 0.3678283 0.3663 0.3656 0.3661284 0.3661 0.3654 0.3659285 0.3654 0.3645 0.3653286 0.3638 0.3639 0.3639287 0.3627 0.3631 0.3624288 0.3611 0.3611 0.3615289 0.3585 0.3587 0.3594290 0.3556 0.3558 0.3565291 0.352 0.3517 0.3524292 0.3475 0.3467 0.3476293 0.3413 0.3406 0.341294 0.3342 0.3331 0.3337295 0.3247 0.325 0.3248296 0.3155 0.3156 0.3155297 0.2948 0.2942 0.2948298 0.2738 0.2741 0.2746299 0.2561 0.2563 0.2564300 0.2367 0.2366 0.2371


HCl 8ppm

Parameter



Measurement

[sec] 0 3 6[nm] 1.[A] 2.[A] 3.[A]

220 0.364 0.3643 0.3634221 0.3549 0.3553 0.3554222 0.3462 0.3463 0.3459223 0.3402 0.3403 0.3406224 0.3371 0.3377 0.3375225 0.3358 0.3359 0.3362226 0.3359 0.3362 0.3367227 0.3379 0.3383 0.3381228 0.3414 0.3417 0.3414229 0.3456 0.3458 0.3457230 0.3509 0.3515 0.3513231 0.3572 0.3578 0.3578232 0.3652 0.3656 0.3652233 0.3733 0.3737 0.3739234 0.3821 0.3831 0.3828235 0.392 0.3924 0.3919236 0.4104 0.4113 0.4107237 0.4205 0.4209 0.421238 0.4301 0.4302 0.4292239 0.4386 0.4394 0.4381240 0.4461 0.4464 0.4463241 0.4532 0.4533 0.4532242 0.4591 0.4591 0.4586

243 0.4637 0.4638 0.4637244 0.4658 0.4661 0.466245 0.468 0.4676 0.4678246 0.4679 0.468 0.4679247 0.4666 0.4665 0.466248 0.4631 0.4635 0.4629249 0.4584 0.4589 0.4588250 0.4536 0.4541 0.4531251 0.4427 0.4428 0.4424252 0.4365 0.4368 0.4357253 0.4315 0.4315 0.4314254 0.4278 0.4277 0.4276255 0.4258 0.4259 0.4254256 0.4239 0.4246 0.424257 0.4233 0.424 0.4233258 0.4238 0.4241 0.4234259 0.4244 0.4247 0.4237260 0.4252 0.4255 0.4246261 0.4261 0.4268 0.4256262 0.4265 0.4275 0.427263 0.4278 0.4289 0.4281264 0.4291 0.4295 0.4284265 0.4289 0.4293 0.4288266 0.4291 0.4298 0.4285267 0.4279 0.4287 0.4275268 0.4268 0.4275 0.4266269 0.4254 0.4256 0.425270 0.4228 0.4236 0.4229271 0.4215 0.4223 0.4214272 0.4196 0.4204 0.4191273 0.4174 0.419 0.417274 0.4154 0.4164 0.4155275 0.4123 0.4136 0.4127276 0.4103 0.4121 0.41277 0.4093 0.4095 0.409278 0.407 0.4078 0.4066279 0.4055 0.4063 0.4053280 0.405 0.4057 0.4042281 0.4042 0.405 0.4033282 0.4056 0.4051 0.4039283 0.4047 0.4059 0.4045284 0.406 0.4077 0.4055285 0.4064 0.4083 0.4063286 0.4071 0.4086 0.4075287 0.408 0.4085 0.4072288 0.4076 0.4077 0.4059289 0.4056 0.4065 0.4043290 0.403 0.4043 0.4024

291 0.3992 0.4002 0.3984292 0.3943 0.3952 0.3932293 0.3883 0.3893 0.3875294 0.38 0.3814 0.3799295 0.3706 0.3713 0.3699296 0.3594 0.3607 0.3595297 0.3354 0.3366 0.3348298 0.313 0.3137 0.312299 0.2928 0.2941 0.2919300 0.2706 0.2716 0.2702


HCl 8ppm

Parameter



Measurement

[sec] 0 3 6[nm] 1.[A] 2.[A] 3.[A]

220 0.3825 0.3817 0.3818221 0.3722 0.3721 0.3714222 0.3627 0.3625 0.3623223 0.3567 0.3558 0.3557224 0.3529 0.3524 0.3527225 0.3507 0.3503 0.3507226 0.3512 0.3511 0.3507

227 0.3521 0.3524 0.352228 0.3553 0.3552 0.355229 0.3595 0.359 0.3589230 0.3641 0.3641 0.3641231 0.37 0.3699 0.3705232 0.3777 0.3774 0.3773233 0.3853 0.3851 0.3852234 0.3937 0.3933 0.3936235 0.4025 0.4025 0.4024236 0.4198 0.4198 0.4196237 0.4298 0.4292 0.4289238 0.4379 0.4378 0.4378239 0.4462 0.446 0.4459240 0.453 0.4527 0.4527241 0.4599 0.4593 0.4592242 0.4649 0.4642 0.4645243 0.4687 0.4686 0.4686244 0.4709 0.4706 0.4709245 0.4722 0.4719 0.4716246 0.472 0.4713 0.4716247 0.4698 0.4693 0.4696248 0.4666 0.4661 0.466249 0.4613 0.4613 0.4616250 0.4565 0.4565 0.4559251 0.4451 0.4454 0.4449252 0.4393 0.439 0.4388253 0.4346 0.4344 0.4342254 0.4311 0.431 0.4308255 0.429 0.4286 0.4286256 0.4275 0.4271 0.427257 0.4273 0.4269 0.4266258 0.4277 0.4275 0.427259 0.4282 0.4283 0.4282260 0.4296 0.429 0.4294261 0.4308 0.4308 0.4306262 0.4322 0.4319 0.4317263 0.4338 0.4332 0.4335264 0.4345 0.4347 0.4344265 0.4359 0.4355 0.4353266 0.4361 0.4358 0.4355267 0.4361 0.4365 0.4356268 0.4362 0.4356 0.4352269 0.4357 0.4356 0.4344270 0.4341 0.4348 0.434271 0.4334 0.4343 0.4336272 0.4332 0.4325 0.4321273 0.432 0.4322 0.4312274 0.4307 0.431 0.4307

275 0.4301 0.4302 0.4298276 0.4296 0.4295 0.4288277 0.4282 0.4288 0.4286278 0.4275 0.4282 0.4283279 0.4283 0.4283 0.4274280 0.4283 0.4287 0.4279281 0.4297 0.4302 0.4294282 0.4331 0.4326 0.4325283 0.4352 0.435 0.4343284 0.4378 0.4377 0.4374285 0.4402 0.4398 0.4391286 0.4421 0.4409 0.4413287 0.4435 0.442 0.442288 0.4434 0.4423 0.4422289 0.4413 0.4407 0.441290 0.4394 0.439 0.4391291 0.436 0.4351 0.4353292 0.4308 0.4308 0.4308293 0.4246 0.4242 0.4242294 0.4165 0.4148 0.4153295 0.4059 0.4055 0.4053296 0.3937 0.3939 0.3939297 0.3678 0.3681 0.3678298 0.3432 0.3428 0.343299 0.3216 0.321 0.3213300 0.2975 0.2967 0.2968


HCl 8 ppm

Parameter



Measurement

[sec] 0 3 6[nm] 1.[A] 2.[A] 3.[A]

220 0.3969 0.3968 0.396221 0.3857 0.3862 0.3856222 0.3758 0.3754 0.3758223 0.3691 0.3689 0.369224 0.3653 0.3653 0.3653225 0.3632 0.3631 0.3636226 0.3634 0.3635 0.3633227 0.3646 0.3645 0.3644228 0.3677 0.3678 0.3678229 0.3715 0.3717 0.3716230 0.3767 0.3765 0.3765231 0.3825 0.3826 0.3825232 0.3898 0.3896 0.3899233 0.3971 0.3974 0.3972234 0.4057 0.4056 0.4057235 0.4143 0.414 0.4146236 0.4313 0.4312 0.4313237 0.4404 0.4402 0.4405238 0.4484 0.4484 0.4481239 0.4562 0.4565 0.4562240 0.463 0.4624 0.4626241 0.4686 0.4685 0.4688242 0.4733 0.4737 0.4737243 0.4769 0.4767 0.4763244 0.4788 0.4785 0.4789245 0.4795 0.4794 0.4794246 0.4791 0.4782 0.4786247 0.4767 0.4767 0.4763248 0.4731 0.4728 0.4725249 0.4679 0.4682 0.4679250 0.4621 0.4622 0.4624251 0.4504 0.4501 0.4508252 0.4443 0.4447 0.4443253 0.4392 0.4395 0.4396254 0.4361 0.4361 0.4367255 0.4342 0.434 0.4341256 0.4326 0.4329 0.4326257 0.4327 0.433 0.4331258 0.4338 0.4332 0.4341

259 0.4345 0.4348 0.4348260 0.4361 0.4359 0.4365261 0.4381 0.4383 0.4379262 0.4398 0.4391 0.4395263 0.4417 0.4413 0.4413264 0.4428 0.4424 0.4427265 0.4447 0.4442 0.4443266 0.446 0.4459 0.4456267 0.4475 0.4478 0.4473268 0.4486 0.4479 0.4482269 0.4488 0.4483 0.4483270 0.4487 0.4484 0.4483271 0.4488 0.4489 0.4487272 0.4483 0.4481 0.4486273 0.4488 0.4483 0.4487274 0.4488 0.4496 0.449275 0.4492 0.4488 0.4484276 0.4494 0.4494 0.4495277 0.4506 0.45 0.4502278 0.4505 0.4508 0.4509279 0.451 0.4521 0.4518280 0.4539 0.4539 0.4538281 0.456 0.4563 0.4564282 0.4621 0.461 0.4611283 0.4654 0.4657 0.4657284 0.4694 0.4689 0.4687285 0.4727 0.4722 0.4719286 0.4744 0.4747 0.4754287 0.4764 0.4757 0.4768288 0.4769 0.4773 0.4769289 0.4765 0.4768 0.4763290 0.4755 0.475 0.4749291 0.4718 0.472 0.472292 0.4662 0.4674 0.4673293 0.4595 0.4598 0.4599294 0.4507 0.4512 0.451295 0.4403 0.4401 0.4405296 0.4276 0.4273 0.4269297 0.3998 0.3997 0.3988298 0.3734 0.3727 0.3727299 0.3493 0.349 0.3492300 0.3227 0.3225 0.3223

2. Kurva Scanning Absorbansi Piridoksin HCl dengan Internal Standar Thiamin

HCl

Kurva 2.1. Absorbansi Piridoksin HCl 8 ppm dengan Internal Standar

Thiamin HCl 8ppm


Thiamin HCl 8ppm


Thiamin HCl 8ppm


Thiamin HCl 8ppm


Thiamin HCl 8ppm

Kurva 2.6. Absorbansi Piridoksin HCl unknown ppm( unknown sample)

dengan Internal Standar Thiamin HCl 8ppm

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