Laboratory Data in Nutrition Assessment

Laboratory Data in Nutrition Assessment

Chapter 18Chapter 18

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Nutrition Laboratory DataNutrition Laboratory Data

Information about

—Nutrition status obtained from controlled physical, chemical (biochemical), molecular diagnostic, or microscopic examination of specimens of body tissues, fluids, and wastes

Information about

—Nutrition status obtained from controlled physical, chemical (biochemical), molecular diagnostic, or microscopic examination of specimens of body tissues, fluids, and wastes

© 2004, 2002 Elsevier Inc. All rights reserved.

Specimen TypesSpecimen Types

Serum

Plasma

Erythrocytes

Leukocytes

Other tissues

Urine

Feces

Serum

Plasma

Erythrocytes

Leukocytes

Other tissues

Urine

Feces

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Types of AssaysTypes of Assays

Static assays

Functional assays

Static assays

Functional assays

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Protein EvaluationProtein Evaluation

Negative acute-phase respondents

Positive acute-phase respondents

Nitrogen balance

Negative acute-phase respondents

Positive acute-phase respondents

Nitrogen balance

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Properties of Proteins Commonly Used in Protein-Energy AssessmentProperties of Proteins Commonly Used in Protein-Energy Assessment

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AnemiaAnemia

Condition characterized by a reduction in the number of erythrocytes per unit of blood volume, or a decrease in hemoglobin content of blood to below the level of usual physiologic need

Hemoglobin concentration below the 95th percentile

Microcytic vs. macrocytic

Condition characterized by a reduction in the number of erythrocytes per unit of blood volume, or a decrease in hemoglobin content of blood to below the level of usual physiologic need

Hemoglobin concentration below the 95th percentile

Microcytic vs. macrocytic

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Laboratory Tests for Iron Deficiency AnemiaLaboratory Tests for Iron Deficiency Anemia

Serum iron

Total iron-binding capacity

Transferrin saturation

Zinc protoporphyrin: heme ratio and free-erythrocyte protoporphyrin

Ferritin

Serum transferrin receptor (sTfR) test

Serum iron

Total iron-binding capacity

Transferrin saturation

Zinc protoporphyrin: heme ratio and free-erythrocyte protoporphyrin

Ferritin

Serum transferrin receptor (sTfR) test

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Malabsorption SyndromeMalabsorption Syndrome

Refers to a condition in which several nutrients are not normally absorbed

Refers to a condition in which several nutrients are not normally absorbed

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Screening for MalabsorptionScreening for Malabsorption

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Constituents of Common Serum Chemistry PanelsConstituents of Common Serum Chemistry Panels

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Constituents of the Hemogram: Complete Blood Count and DifferentialConstituents of the Hemogram: Complete Blood Count and Differential

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Constituents of the Hemogram: Complete Blood Count and Differential — cont’dConstituents of the Hemogram: Complete Blood Count and Differential — cont’d

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Chemical Tests in a UrinalysisChemical Tests in a Urinalysis

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Chemical Tests in a Urinalysis –cont’dChemical Tests in a Urinalysis –cont’d