KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent...

9
KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng, Pirita Pekkonen, Simonas Laurinavicius, Nami Sugiyama, Stephen Henderson, Thomas Günther, Ville Rantanen, Elisa Kaivanto, Mervi Aavikko, Grzegorz Sarek, Sampsa Hautaniemi, Peter Biberfeld, Lauri Aaltonen, Adam Grundhoff, Chris Boshoff, Kari Alitalo, Kaisa Lehti, Päivi M. Ojala Cell Host & Microbe Volume 10, Issue 6, Pages 577-590 (December 2011) DOI: 10.1016/j.chom.2011.10.011 Copyright © 2011 Elsevier Inc. Terms and Conditions

Transcript of KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent...

Page 1: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase-Dependent Lymphatic Endothelial-to-Mesenchymal Transition 

Fang Cheng, Pirita Pekkonen, Simonas Laurinavicius, Nami Sugiyama, Stephen Henderson, Thomas Günther, Ville Rantanen, Elisa Kaivanto, Mervi Aavikko, Grzegorz Sarek, Sampsa Hautaniemi, Peter Biberfeld, Lauri Aaltonen, Adam Grundhoff, Chris Boshoff, Kari

Alitalo, Kaisa Lehti, Päivi M. Ojala 

Cell Host & Microbe Volume 10, Issue 6, Pages 577-590 (December 2011)

DOI: 10.1016/j.chom.2011.10.011

Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 2: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 1

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 3: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 2

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 4: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 3

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 5: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 4

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 6: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 5

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 7: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 6

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 8: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Figure 7

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions

Page 9: KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase- Dependent Lymphatic Endothelial-to-Mesenchymal Transition Fang Cheng,

Cell Host & Microbe 2011 10, 577-590DOI: (10.1016/j.chom.2011.10.011) Copyright © 2011 Elsevier Inc. Terms and Conditions