INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a...
Transcript of INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a...
![Page 1: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/1.jpg)
INTRODUCTION TO PATHOLOGY
Dr Heyam Awad
MD, FRCPATH, Jordanian Board
LECTURE 1
![Page 2: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/2.jpg)
Introduction to pathology
![Page 3: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/3.jpg)
Today’s lecture
• Introduction aiming at:
1.Introducing you to the course.
2. What is pathology ?
3. What do pathologists do?
![Page 4: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/4.jpg)
The course
• Two credit hours course
• Three main subjects will be covered:
1. Cell injury
2. Inflammation
3. Neoplasia
![Page 5: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/5.jpg)
reference
- Robbins basic pathology, Kumar Abbas and Aster, 10th edition.
- My slides are a summary of the book!
![Page 6: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/6.jpg)
Course design!
topic instructor No of lectures Book chapter
Cell injury Dr Heyam Awad 5 1
Inflammation and repair Dr Mousa Abbadi 10 2
neoplasia Dr Maha shomaf 10 5
![Page 7: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/7.jpg)
My lectures
• Two sets of slides:
• 1.A detailed one which you need to study from
This will be on my web page and on the e learning site before the lecture day .
2. A FUN version that includes mainly pictures.. This will aid us discussing the subject
Do we need sheets?.. How to study?
![Page 8: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/8.jpg)
assessment
*Mid term.. 40 marks ..Around week 7material: cell injury and inflammation
*Final exam.. 50 marksmaterial: repair and neoplasia
*Attendance marks.. 10please note: school of medicine is strict
about attendance..
![Page 9: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/9.jpg)
The best way to deal with my lectures!
• 1. attend the lectures and try to understand
• 2. read the slides carefully.. They are detailed.. I put everything you need for the exam there
• 3. I encourage you to read the book: chapter 1
• 4. keep checking the e-learning, I’ll put resources and sample questions there.
• KEEP CALM AND ENJOY
![Page 10: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/10.jpg)
![Page 11: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/11.jpg)
MY RULES!!!
• First: your rights
• To be respected
• To enjoy each 50 minutes here
• To understand
• And: please ask questions.. Give comments.. And challenge me!
![Page 12: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/12.jpg)
Remember:
![Page 13: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/13.jpg)
Lecture RULES: your duty!
• Give me your full attention!
![Page 14: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/14.jpg)
What about coffee?
![Page 15: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/15.jpg)
Contact details
• Office hours: 2-3 daily
• My office is in the hospital, third floor
• You can also see me outside the office hours, if I’m not in the office I’ll be in the histopathology department in the same floor(third)
• E mail: [email protected]
• Also: keep checking e learning for announcements.
![Page 16: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/16.jpg)
What is pathology?
• Patho = disease
• Logy = study
• So pathology is the study of disease =علم االمراض
![Page 17: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/17.jpg)
Pathology studies three main aspects of the disease process:
• Etiology
• Pathogenesis
• morphology
![Page 18: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/18.jpg)
Etiology.. The “why” question
• = the origin of disease= the underlying cause.
![Page 19: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/19.jpg)
Pathogenesis.. “HOW”
• Steps in the development of disease.
• Describes how etiologic factors trigger cellular and molecular changes that give rise to functional and structural abnormalities.
• Disease occur in a multistep organized fashion..
![Page 20: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/20.jpg)
pathogenesis
• Message: as a doctor you need critical thinking, splitting things into precise steps and stages
![Page 21: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/21.jpg)
morphology
• The changes seen on tissues and organs that help diagnosing the disease
• Gross= macroscopic morphology: changes seen by naked eye
• Microscopic morphology: changes seen under the microscope.
![Page 22: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/22.jpg)
Gross morphology .. Can you describe ?
![Page 23: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/23.jpg)
![Page 24: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/24.jpg)
morphology
![Page 25: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/25.jpg)
Histopathology is fun..
![Page 26: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/26.jpg)
What do pathologists do?
![Page 27: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/27.jpg)
Sample obtained.. how
![Page 28: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/28.jpg)
Sample received in lab
![Page 29: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/29.jpg)
HOW DOES THESE SAMPLES CHANGE INTO GLASS SLIDES???
![Page 30: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/30.jpg)
![Page 31: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/31.jpg)
Grossing = cutting the sample
![Page 32: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/32.jpg)
Processing to a paraffin block
![Page 33: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/33.jpg)
Cutting.. By a microtome
![Page 34: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/34.jpg)
Staining the slide
![Page 35: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/35.jpg)
Ready to be read by the pathologist
![Page 36: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/36.jpg)
The pathology report
• We convey what we see under the microscope in a written report.
• The report includes macroscopic ( gross) and microscopic description.
• It gives you information about: the diagnosis, the prognosis and probably the underlying cause.
![Page 37: INTRODUCTION TO PATHOLOGY - · PDF fileInflammation 3. Neoplasia. ... - My slides are a summary of the book! Course design! ... What is pathology? •Patho = disease](https://reader031.fdocuments.net/reader031/viewer/2022021817/5a9d98a87f8b9a21688cc72a/html5/thumbnails/37.jpg)