SIXTH INTERNATIONAL IMMUNOLOGY SUMMITOptimizing management of musculoskeletal diseases:

treating the human and the being

Chair: Peter Taylor

Prague, 1214 March 2015

First announcement

This educational event is organized by UCB

All attendees will have the opportunity to participate in a number of mini-symposia. All workshops will be facilitated by expert faculty. Further information about these sessions and how to register for your preferred option will be available on our upcoming website.

Topics will include Patient communication workshop: how can your patient help you treat their

disease better?

Pain and the brain: how neuroscience neurobiology helps us deal better with rheumatic disease

Therapeutic drug monitoring strategies

Managing co-morbidities in rheumatic diseases: the impact of peripheral inflammation on body and mind

Detecting depression and anxiety disorders in rheumatic diseases: practical tips, everyday solutions

Interpreting MRI in AxSpA

Challenging cases in AxSpA: right patient, right treatment

Diagnosis and monitoring of AxSpA in the clinic

Beyond evidence-based medicine: what have we learned about biologic therapies in observational studies?

Difficult cases in rheumatology: RA and PsA

Use of musculoskeletal ultrasound in rheumatic disease: RA and PsA

Diagnosis and management of PsA: a shared responsibility between disciplines

How do we manage pregnancy in women suffering from RA/AxSpA/PsA?

Clinical care of vasculitis

Programme may be subject to change

Planned mini-symposia sessions

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Throughout the Summit, there will be opportunities to participate in a number of mini-symposia.

Summit Open

Session chairPeter TaylorFacultyMaxime Dougados Karel Pavelka Jiri Vencovsky

Welcome reception and Summit introduction

Beyond treat-to-target: a holistic approach to treatment of rheumatic diseases

Session chairPeter TaylorFacultyRakesh Jain Laure Gossec

Putting patients at the heart of care: changing needs in the face of evolving therapies

Treating the mind and the body: an integrated approach to chronic pain

Patient-reported outcomes: their views can help us improve their wellbeing

Improving the patient experience in SLE

Session chairThomas DrnerFacultyIan Bruce Susan Manzi

B cell biology in the SLE disease course: why this matters

Practical guidance on treatment goals in SLE

Best practice for management of co-morbidities

Management of disorders of bone in immunoinflammatory disease: do we need to do more?Session chair Socrates PapapoulosFacultyEugene McCloskey Lorenz Hofbauer

New insights on the pathophysiology of inflammation-induced bone disease

Effects of current therapeutics on BMD and fracture risk

Beyond inhibition of excess bone remodelling

Clinical care of vasculitisSession chair Ian BruceFacultyDavid DCruz Stephen Hall

State-of-the-art in vasculitis management

Optimizing pharmacology in RA: what are the patient outcomes beyond symptom control?Session chair Maxime DougadosFacultyMichael Schiff Gerd Burmester Christopher D Buckley

Global perspectives: management of early RA optimized MTX and early use of biologic therapy to improve long-term outcomes

Towards early arthritis management: a TEAM approach

It is with great pleasure that I warmly invite you to the Sixth International Immunology Summit on Optimizing management of musculoskeletal diseases: treating the human and the being.

We have witnessed extraordinary advances in the understanding of musculoskeletal diseases over the past decade and a half, as well as an increase in pharmacotherapeutic options. However, despite the greatly improved outlook for patients with certain conditions, such as rheumatoid arthritis and axial spondyloarthritis, very significant unmet needs remain. While severe disability has fortunately become less common, and more patients remain in employment, they may still face difficulties that may not be immediately apparent to their physicians, e.g. pain and fatigue. We

must now look at the total burden of chronic disease in our patients lives and how best we can optimize every aspect of their quality of life.

Much of the therapeutic advance of recent years has focused on improving immune dysregulation in the assumption that emotional, mental and global health will improve correspondingly. Indeed, while this is sometimes the case, there is often discordance between improvements in objective measures of disease activity and the patients own assessment of their wellbeing. It might be said that optimizing pharmacotherapeutic intervention has focused on the pathophysiological aspects of human disease. In English we refer to our species as human beings, so there is another dimension to us the being beyond the physiological alone, which determines how we perceive and experience the world. Of course, these two aspects, the human and the being are interdependent our feelings affect our health and our health affects our perceptions and emotions.

The objective of the Summit is to discuss, share and learn how we can adopt a more holistic approach to caring for our patients beyond simply modifying disease activity, that is, how can we aspire to optimize patient wellbeing? We have an exciting programme and are fortunate in having a prestigious faculty to inspire and help us on our journey. Discussions will encompass the spectrum of rheumatic disease PsA, AxSpA, RA and SLE as well as disorders of bone and the challenges of family planning and pregnancy in autoimmune conditions. New this year is a state-of-the-art plenary session on vasculitis. In addition to the plenaries, mini-symposia sessions will explore and expand on the plenary topics and give attendees the opportunity to meet with faculty and one another in smaller groups.

Our intention is to foster an atmosphere of sharing and participation through the use of interactive formats including debates, panel discussions, case studies and hands-on workshops. We will also harness the latest in multimedia technology to enhance learning.

I look forward to welcoming you to Prague.

Professor Peter TaylorUniversity of Oxford, UK

Evolution to revolution: progress in the understanding and management of AxSpA

Session chairDsire van der HeijdeFacultyMartin Rudwaleit Filip van den Bosch Robert Landew Dominique Baeten

The importance of early, accurate diagnosis in AxSpA

Practical guidance on managing extra-articular features to improve patients daily lives

Disease modification in AxSpA

Current management, and emerging pathways, treatment targets and strategies

Virtual clinic: interactive case

How can we optimize management in PsA to further enhance patients lives?

Session chairIain McInnesFacultyPeter Nash Wolf-Henning Boehncke

Living with the dual burden of PsA: the patient viewpoint

Practical guidance on managing comorbidities in PsA wellbeing as a therapeutic target

The future of PsA management emerging strategies and therapies

Challenges in planning and managing pregnancy in autoimmune diseaseSession chairDimitrios BoumpasFacultyCatherine Nelson-Piercy

The patient-physician journey: what can we do for better outcomes? Viewpoints from the patient, the obstetric physician and the rheumatologist

Day and Summit Close

Session chairPeter Taylor

Programme may be subject to change

ProgrammeDear Colleagues and Friends

Inside left page 148 mm

Inside middle!48 mm

Inside right page (Folds in under left page) 146 mm

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