Slide 1

I NTRODUCTION TO LABORATORY MEDICINE

Slide 2

L IPID CHEMISTRY AND CARDIOVASCULAR PROFILE Main lipids in the blood are the triglycerides and cholesterol. These are insoluble in the water. Transport in the blood is via lipoproteins. 4 major classes of lipoproteins. Chylomicrons Very low density lipoproteins (VLDL) Low density lipoproteins (LDL) High density lipoproteins (HDL)

Slide 3

L IPOPROTEINS COMPOSITIONS

Slide 4

C OMPOSITION OF LIPOPROTEINS Class Diamete r (nm) % protein % cholesterol % phospholipi d % triacylglyc erol & cholesterol ester HDL 5153330294 LDL 18282550218 IDL 255018292231 VLDL 308010221850 Chylomicr ons 100-1000