Pancreatic enzyme replacement therapy in pancreatic insufficiency
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport on behalf of the Hungarian...
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Transcript of Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport on behalf of the Hungarian...
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
on behalf ofthe Hungarian Pancreatic Study Group
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
PINEAPPLE
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
Analyses of Pediatric Pancreatitis
APPLE
Andrea PárniczkyBUDAPEST, HUNGARY
Analyses of Pediatric Pancreatitis
APPLE
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
CHILDREN
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
1. The protocols have been discussed in our latest international meeting held in Szeged in November 2014, where expert pediatric pancreatologists attended. (http://pancreas.hu/sites/info/files/conferences/ALPD2014-Program.pdf)
2. The studies have received the relevant ethical approval (No. ad.52499-3/2014) issued by the National Hungarian Ethical Authority (ETT TUKEB).
3. The trial has been registered at the ISRCTN registry (ISRCTN89664974) which is a primary clinical trial registry recognized by WHO and ICMJE.
4. The study is open for all pediatric centers throughout the world.5. Electronic CRF has been developed.6. The IAP Scientific Committee has approved the study and advertised
worldwide among its 4000 members (16.06.2015)7. The TRIAL article (prestudy protocol) is accepted, will be published in Digestion
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
Number of centres: 12
PINEAPPLE
APPLE
SZEGED
BUDAPEST
NYÍREGYHÁZA
DEBRECEN
PÉCS
SZEKSZÁRD
ZALAEGERSZEG
SZÉKESFEHÉRVÁR
BALASSAGYARMAT
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
APPLE
Understand our EARLIER PRACTICE in pediatric pancreatitis
Specify the GENETIC BACKGROUND of pediatric pancreatitis
APPLE-R
Understand the FAMILY HISTORY in pediatric pancreatitis
Patients with HISTORY of pancreatitis under 18 ys
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
APPLE
APPLE-R
Acute Pancreatitis (AP) Acute Recurrent Pancreaitis (ARP) Chronic Pancreatitis (CP) Autoimmune Pancreatitis (AIP) Pancreatic Cancer (PC)
+Other diseases
Details from the medical history
Etiology
Genetic Test if available
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
APPLE
2 TUBES (EDTA)OF BLOOD
SHIP TOSZEGED
Storage - 20 C ͦ
FOR GENETIC ANALYSES
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups APPLE
Analyses of Pediatric Pancreatitis
It has to be cost effectiveWe can offer an unbeatable cost effective way for you:
WE WILL DO IT FOR FREE!
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
GET MORE DETAILS and RECOGNIZE BETTER the course of the pediatric pancreatitis
Specify the GENETIC BACKGROUND of pediatric pancreatitis
Identify EARLY RISK FACTORS (etc: smoking-first, second-hand)
Establishment of the SEVERITY at admission
APPLE-PNEWLY diagnosed patient under 18 ys with pancreatitis
(PINEAPPLE CAN HELP)
APPLE4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
Admission details, status
Laboratory parameters at admission
Amylase (U/l)Lipase (U/l) (only obligatory if amylase is not measured)White blood cell (WBC) count (G/l)
Red blood cell (RBC) count (T/l)
Hemoglobin (g/l)Hematocrit (%)Thrombocyte (G/l)Serum glucose (mmol/l)Blood urea nitrogen (mmol/l)Creatinine (umol/l)eGFRC-reactive protein (mg/l)ASAT/GOT (U/l)Lactate dehydrogenase LDH (U/l)
Calcium (mmol/l)
OBLIGATORY
Imaging at admission
Details from the medical history
Abdominal US
Chest CT Chest X-ray
Abdominal CTAbdominal X-ray
AT ADMISSION!
Immediate therapy at admission
Complications
Complains, symptoms
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
APPLEAnalyses of Pediatric Pancreatitis
APPLE
FOR EVERY DAY!
Every day of the hospitalization the “APPLE-P FORM-B Questionnaire daily” needs to be filled out.
General medical treatment
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
APPLEAnalyses of Pediatric Pancreatitis
Hungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
Thank you for joining to us!
We are waiting for more We are waiting for more centres!centres!
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE
THE HUNGARIAN PANCREATIC STUDY GROUPIS COMMITTED TO IMPROVING
THE LIVE OF PATIENTS SUFFERING FROM PANCREATIC DISEASES!
www.pancreas.huHungarian Pancreatic Study Group – Magyar Hasnyálmirigy Munkacsoport
4th Conference of the Hungarian & 2nd Conference of the Eastern and Central European Pancreatic Study Groups
Analyses of Pediatric Pancreatitis
APPLE