HERBAL REMEDIES, SUPPLEMENTS AND CBD: ARE THEY SAFE?DO THEY WORK?

TREVOR CHRIST, PHARMD, BCOPType to enter a caption.

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

OBJECTIVES

▸ Provide key definitions and statistics

▸Describe regulatory oversight of herbal supplements

▸Discuss potential benefits and harms of herbal supplement and CBD use in lymphoma patients

▸ Provide conclusions, resources, and parting advice

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

DEFINITIONS

▸Dietary Supplements

▸ Complementary medicine

▸Alternative medicine

https://nccih.nih.gov/health/supplements. Accessed August 14, 2019.

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

REGULATORY OVERSIGHT OF DIETARY SUPPLEMENTS

▸Dietary Supplement and Health Education Act (DSHEA) of 1994

▸ Federal Drug Administration’s (FDA) responsibilities

▸ Federal Trade Commission’s (FTC) responsibilities

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

COMPARE TO FDA APPROVED PRESCRIPTION DRUG

Phase IIPre-clinical Phase I Phase III

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

ANATOMY OF LABEL

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

DIETARY SUPPLEMENTS▸ The Good

▸Added sense of control

▸Many benefits for various CAM practices (Massage, Aroma therapy, etc.)

▸Nutritional supplementation for vitamin deficiency

▸ The Bad

▸ The Ugly

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

DIETARY SUPPLEMENTS▸ The Good

▸ The Bad

▸ Limited benefits in cancer population

▸ Safety

▸ Drug interactions

▸ Cost

▸ Misinformation

▸ The Ugly

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

DRUG INTERACTIONS

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

DIETARY SUPPLEMENTS▸ The Ugly

▸ Severe liver damage

▸ Increased risk of death in patients choosing alternative medicine over conventional medicine (patients with curative cancers)

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

CBD OIL

▸What is it?

▸What do we know about it?

▸ Is it legal?

▸ Is it safe?

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

WHAT YOU CAN DO

▸ If interested in an herbal supplement, talk to your doctor or pharmacist

▸Don’t exceed recommended doses

▸ Keep track of what you take and only start one supplement at a time.

▸ Research the expected onset of action of the effect you’re looking for (might not always be available) and decide if it’s worth continuing to take

▸ Choose brands with either consumerlabs.com or U.S. Pharmacopeia convention

▸Don’t just trust label and other marketing material, talk to your doctor or pharmacist and research validated websites

▸ Check safety alerts on the FDA website

HERBAL SUPPLEMENTS, REMEDIES AND CBD: ARE THEY SAFE? DO THEY WORK?

RESOURCES

▸ https://ods.od.nih.gov/factsheets/list-all/

▸ https://www.mskcc.org/cancer-care/diagnosis-treatment/symptom-management/integrative-medicine/herbs/search

HERBAL REMEDIES, SUPPLEMENTS AND CBD: ARE THEY SAFE?DO THEY WORK?

TREVOR CHRIST, PHARMD, BCOPType to enter a caption.