GNIPST Bulletin 47.1

10-07-2015

GGGNNNIIIPPPSSSTTT BBBUUULLLLLLEEETTTIIINNN 22200011155510th July, 2015 Volume No.: 47 Issue No.: 01

Vision

TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE

BASED LEARNING AND PRACTICE

Contents Message from PRINCIPAL Editorial board Historical article News Update Knowledge based Article Disease Related Breaking

News Upcoming Events Drugs Update Campus News Students Section Editors Note Archive

GNIPST Photo Gallery For your comments/contribution OR For Back-Issues, mailto:[email protected]

GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY

W e bs i t e : ht t p: / / gni ps t. a c. i n

10-07-2015

MESSAGE FROM PRINCIPAL

"It can happen. It does happen. But it can't happen if you quit." Lauren Dane.

We are what we repeatedly do. Excellence then is not an act, but a habit. Aristotle

It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank the last years editors and congratulate the newly selected editors for the current year.

Our first consideration is always in the best interest of the students. Our goal is to promote academic excellence and continuous improvement.

I believe that excellence in education is aided by creating a learning environment in which all learners are supported in maximizing their potential and talents. Education needs to focus on personalized learning and instruction, while promoting an education system that is impartial, universally accessible, and meeting the needs of all students.

It is of paramount importance that our learners have sufficient motivation and encouragement in order to achieve their aims. We are all very proud of you, our students, and your accomplishments and look forward to watching as you put your mark on the profession in the years ahead.

The call of the time is to progress, not merely to move ahead. Our progressive Management is looking forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken in this direction and fruits of these efforts will be received by our students in the near future. Our Teachers are committed and dedicated for the development of the institution by imparting their knowledge and play the role of facilitator as well as role model to our students.

The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positive challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holistic needs of our students.

I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of the opportunities and meet the challenges with purpose and determination.

Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us on this path.

My best wishes to all.

Dr. A. Sengupta

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EDITORIAL BOARD

CHIEF EDITOR DR. ABHIJIT SENGUPTA EDITOR MS. JEENATARA BEGUM ASSOCIATE EDITOR MR. DIPANJAN MANDAL

HISTORICAL ARTICLE Louis Pasteur (1822 1895) Louis Pasteur worked tirelessly to develop antidotes and cures to many dangerous illnesses such as anthrax and rabies. He also successfully invented a way to pasteurise milk and make it safe from Tuberculosis. Louis Pasteur was born in Dole, Eastern France. He was a conscientious and hard working student, though not considered exceptional. One of his professors called him mediocre. He received a doctorate in 1847 and after obtaining posts at Strasbourg, Lille and Paris he spent much time researching aspects of Chemistry. One key discovery related to research on tartrate acid showing the crystals contained a mirror image of right-handed and left handed isomers. His most important discoveries were in the field of germ study. He showed that germs required certain micro-organisms to develop; using this knowledge he found that the fermentation of yeast could be delayed. Louis Pasteur then turned to practical ways of killing bacteria in liquids such as milk. His process of pasteurisation successfully killed bacteria in milk without destroying milk protein. This was a radical discovery and made drinking milk safe. The process of pasteurisation was named after him and it saved many lives. Louis Pasteur was a great believer in hard work, never content to rest on his laurels he continued to work very hard in his laboratory to develop more cures. Louis Pasteur next created a cure for anthrax a disease that mainly affects cattle. He found that by giving cattle a weakened


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form of the illness they were able to develop immunity to the illness. This success encouraged him to develop a cure for rabies a very common disease at the time. Using similar principles he developed a weakened strain of the disease. Louis died in 1895 aged 73. NEWS UPDATE Findings identify receptors modulating

macrophage responses to spinal cord injury: 10th July, 2015 A new studysheds light on opportunities to modulate macrophage responses after spinal cord injury, potentially reducing -- or even reversing -- damage and the resulting side effects.

Using garlic to combat antimicrobial resistant urinary tract infections: 10th July, 2015 Garlic extract may be an effective weapon against multi-drug resistant strains of pathogenic bacteria associated with urinary tract infections (UTI), according to a recent study.

Ancestral diets determine vulnerability to type 2 diabetes: 10th July, 2015 The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today's changing environment. New research reveals this may be a result of the nutrition endured by their ancestors.

Role of microbiota in preventing allergies: 10th July, 2015 The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. It is well established that a loss of bacterial symbionts promotes the development of allergies. Scientists have succeeded in explaining this


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phenomenon, and demonstrate how the microbiota acts on the balance of the immune system: the presence of microbes specifically blocks the immune cells responsible for triggering allergies.

Cell machinery wears complex coat: 10th July, 2015 Detailed images have been produced of the intricate protein-coats that surround trafficking vesicles - the transport pods that move material around within biological cells. The study provides a new understanding of the complex machines that make up the cells logistics network.

License for cutting: How intracellular signaling regulates growth factor production: 10th July, 2015 Cancer cells need life-essential molecules to proliferate. These so-called growth factors are activated by ectodomain shedding of precursor proteins on the outside of the plasma membrane, mainly carried out by three human cleavage enzymes. A pharmaceutical blocking of these enzymes could hinder cancer from growing but would also inhibit other life-essential processes. Now, researchers have shown that the factor-precursor-producing cells themselves determine if and when cleavage may occur. This is decided by intracellular signaling. Interfering with defined signaling in cells producing cancer growth factors could be developed into a new way of cancer treatment.

Risk of COPD may already occur in adolescence: 10th July, 2015 Chronic obstructive pulmonary disease (COPD) is one of most common causes of death in the world today -- active smoking accounting for approximately 85 percent of all cases. Yet ground-breaking research indicates that accelerated decline of lung function is not a prerequisite for COPD.


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No need to treat stable meniscus tears during ACL surgery: 10th July, 2015 While athletes undergoing anterior cruciate ligament (ACL) surgery often have an additional meniscus injury, treating these tears at the same time may not be necessary. Research shows positive results for meniscal tears that were deemed stable and left alone at the time of ACL reconstruction.

Surgery may be best treatment option for multidirectional shoulder dislocations: 10th July, 2015 While multidirectional instability of the shoulder has been traditionally treated without surgery, research shows that surgery is also effective for this type of dislocation.

'Jumping genes' may drive esophageal cancer: 10th July, 2015 'Jumping genes' may add to the genetic chaos behind more than three-quarters of esophageal cancer cases, scientists have discovered. 'Jumping genes', called L1 elements, can uproot themselves and move to new areas in the DNA, sometimes accidentally moving into genes that control the cell's growth.For detail mail to editor

KNOWLEDGE BASED ARTICLE Gene therapy restores hearing in deaf mice

Using gene therapy, restored hearing in mice with a genetic form of deafness. This work, could pave the way for gene therapy in people with hearing loss caused by genetic mutations. More than 70 different genes are known to cause deafness when mutated. Holt, with Charles Askew and colleagues at cole Polytechnique Fdrale de Lausanne in Switzerland, focused on a gene called TMC1. They chose TMC1 because it is a common cause


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of genetic deafness, accounting for 4 to 8 percent of cases, and encodes a protein that plays a central role in hearing, helping convert sound into electrical signals that travel to the brain. The researchers tested gene therapy in two types of mutant mice. One type had the TMC1 gene completely deleted, and is a good model for recessive TMC1 mutations in humans: Children with two mutant copies of TMC1 have profound hearing loss from a very young age, usually by around 2 years. The other type of mouse, called Beethoven, has a specific TMC1 mutation--a change in a single amino acid--and is a good model for the dominant form of TMC1-related deafness. In this form, less common than the recessive form, a single copy of the mutation causes children to gradually go deaf beginning around the age of 10 to 15 years. To deliver the healthy gene, the team inserted it into an engineered virus called adeno-associated virus 1, or AAV1, together with a promoter--a genetic sequence that turns the gene on only in certain sensory cells of the inner ear known as hair cells. They then injected the gene-bearing AAV1 into the inner ear, with these findings:

In the recessive deafness model, gene therapy with TMC1 restoredthe ability of sensory hair cells to respond to sound--producing ameasurable electrical current--and also restored activity in theauditory portion of the brainstem.

Most importantly, the deaf mice regained their ability to hear. Totest hearing, the researchers placed the mice in a "startle box" andsounded abrupt, loud tones. "Mice with TMC1 mutations will justsit there, but with gene therapy, they jump as high as a normalmouse," says Holt. (The force of their jump was measured by aplate on the floor underneath them; it was detectable at soundsbeginning around 80 decibels.)

In the dominant deafness model, gene therapy with a related gene,TMC2, was successful at the cellular and brain level, and partiallysuccessful at restoring actual hearing in the startle test.Clinical trials on the horizon


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AAV1 is considered safe as a viral vector and is already in use in human gene therapy trials for blindness, heart disease, muscular dystrophy and other conditions. The researchers screened various types of AAV and various types of promoters to choose the best-performing combination. They plan to further optimize their protocol and follow their treated mice to see if they retain hearing longer than the two months already observed. Ultimately, Holt hopes to partner with clinicians at Boston Children's Department of Otolaryngology and elsewhere to start clinical trials of TMC1 gene therapy within 5 to 10 years. "Current therapies for profound hearing loss like that caused by the recessive form of TMC1 are hearing aids, which often don't work very well, and cochlear implants," says Margaret Kenna, MD, MPH, a specialist in genetic hearing loss at Boston Children's Hospital who is familiar with the work. "Cochlear implants are great, but your own hearing is better in terms of range of frequencies, nuance for hearing voices, music and background noise, and figuring out which direction a sound is coming from. Anything that could stabilize or improve native hearing at an early age is really exciting and would give a huge boost to a child's ability to learn and use spoken language." Holt believes that other forms of genetic deafness may also be amenable to the same gene therapy strategy. Overall, severe to profound hearing loss in both ears affects 1 to 3 per 1,000 live births. "I can envision patients with deafness having their genome sequenced and a tailored, precision medicine treatment injected into their ears to restore hearing," Holt says. Sound transducers: How TMC works Holt's team showed in 2013 that TMC1 and the related protein TMC2 are critical for hearing, ending a rigorous 30-year search by scientists. Sensory hair cells in the inner ear contain tiny projections called microvilli, each with a channel at its tip formed by TMC1 and TMC2 proteins. When sound waves wash over the microvilli, they wiggle and the mechanical stimulation causes the


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channel to open. This allows calcium to enter the cell, generating an electrical signal that travels to the brain and ultimately translates to hearing. Although the channel is made up of either TMC1 or TMC2, a mutation in the TMC1 gene is sufficient to cause deafness. However, Holt's study also showed that gene therapy with TMC2 could compensate for loss of a functional TMC1 gene, restoring hearing in the recessive deafness model and partial hearing in the dominant deafness model. "This is a great example of how the basic science can lead to clinical therapies," says Holt. "The implications of successful gene therapy are profound, and we are delighted to be associated with this study program," says Ernesto Bertarelli, co-chair of the Bertarelli Foundation, the primary funder of the research. "These findings mark a defining moment in the way we understand, and can ultimately challenge, the burden of deafness in humans. The results are testament to the immense dedication of the research team and their commitment to bringing best-in-class science ever closer to real-world application."

Jeenatara Begum Assistant Professor

GNIPST

DISEASE RELATED BREAKING NEWS Middle East respiratory syndrome coronavirus

(MERS-CoV) The Philippines: 08th July, 2015 On 6 July 2015, the IHR National Focal Point of the Philippines notified WHO of 1 laboratory-confirmed case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Read more


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UPCOMING EVENTS 61st IPSF World Congress sponsored by Indian Pharmaceutical

Association (IPA) at Marriott Hotel, Hyderabad, India is going to on 30th July to 9th August, 2015.

For further details please visit www.ipsf2015.org DRUGS UPDATES FDA Approves Entresto (sacubitril/valsartan) for

Heart Failure: 07th July, 2015 The U.S. Food and Drug Administration today approved Entresto (sacubitril/valsartan) tablets for the treatment of heart failure. The drug has been shown to reduce the rate of cardiovascular death and hospitalization related to heart failure. Read more

CAMPUS NEWSFAREWELL PROGRAMME:

On 15th May 2015 GNIPST clebrated the farewell programme Sesh Chithi for the final year students of M.Pharm, M.Sc, B.Pharm, B.Sc and BHM.

JIS SAMMAN 2015 On 11th May, 2015 GNIPST attended the JIS SAMMAN 2015.

JIS SAMMAN Awards: Best College (Non Engineering):

GNIPST Best Principal:

Dr (Prof.) Avijit Sengupta Best HOD:

Mr. Jaydip Ray Best Faculty:

Mr. Debabrata Ghoshdastidar (Pharmacy)Dr. Swati Chakraborty (Life Sciences)

Best faculty since inception:


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Mr. Jaydip Ray Best Office Staff:

Ms. Jaya Banerjee Best technical Assistant:

Mr. Somnath Majhi College Blue:

Avik Paul Highest DGPA of 2014:

B.Pharm:Purbali Chakraborty (4th year) Diksha Kumari (3rd year) Aishika Dutta (2nd year) Sampita Paul (1st year) M.Pharm: Aritra Mukherjee (Pharmaceutical Chemistry) Mounomukhar Bhattacharya (Pharmacology) B.Sc (Biotechnology): Papiya Saha (3rd year) Shomasree Das (2nd year) Ayanita Basak (1st year) B.Sc (Microbiology): Bonhisikha Chatterjee (3rd year) Riaz Hossain (2nd year) Soumi Chowdhury (1st year) BHM: Bishal Roy (3rd year) Shreyabhanja Chowdhury (2nd year) Recitation:

Udita Majumder Debate:

Srijita Roy Poushali Ganguly Quiz:


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Arani Ray Dipayan Nath Band:

Syantan Ghoswami Anurag Ghosh Atanu Mondal Arka Khamaru Ritobroto Paul Abhirup Dasgupta

Fashion: Md. Nadeem Shah Koustav Sarkar Shaksar Saha Avirup Dasgupta Ranit Kundu Namrata Ganguly Shreyasee Mitra Chandrika Saha Debopriya Chatterjee Riya Taran

Innovative Modeling: Ankit Chowdhury Kartik Koley Mudasar Manna Dipan Chaterjee Abhishek Singh Kaustav Pal Manojit Dutta

SPIRIT JIS 2015 On 03th to 05th April, 2015 JIS organised SPIRIT JIS 2015. GPAT 2015 Result:

The following B.Pharm. final year students have qualified, GPAT-2015. We congratulate them all. Diksha Kumari


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Rupanjay Bhattacharya Avik Paul Xtasy 2015: GNIPST is going to organize the Tech Fest Xtasy 2015 from 30th March, 2015 to 1st April, 2015.

FINISHING SCHOOL TRAINING PROGRAMME: The FINISHING SCHOOL TRAINING PROGRAMME is going to organize by the Entrepreneurship Development Cell and Training & Placement Cell, GNIPST in collaboration with Indian Pharmacy Graduates Association (IPGA), Bengal Branch from 21st February to 11th April, 2015 at GNIPST Auditorium. On 21

st February, 2015 the Finishing School Training Programme of

GNIPST was inaugurated by Sri Soumen Mukhopadhyay, Deputy Director, Drug Control Office, Goutam Kr. Sen, President, IPGA, Mr. Subroto Saha, Asst. Directorate, Drug Control Office, Mr. Ranendra Chakraborty, Sales Manager and Associate Director Dr. Reddys Laboratory. On 28th February, 2015 Dr. D. Roy, Former Deputy Drug Controller, Mr. Sujoy Chakraborty, divisional Therapy Manager, Cipla and Mr. Vikranjit Biswas, Senior Manager, Learning & Development, Cipla delivered their valuable lectures in the 2nd day FINISHING SCHOOL TRAINING PROGRAMME of GNIPST. On 14th March, 2015 Mr. Milindra Bhattacharya, Senior Manager, QA & QC, Emami Ltd. and Mr. Joydev Bhoumik, Manager, Operation, Ranbaxy Laboratory Limited delivered their valuable lectures in the 3rd day FINISHING SCHOOL TRAINING PROGRAMME of GNIPST. On 21st March, 2015 Mr. Tridib Neogi, Associate Vice-President (Quality Assurance), Albert David Ltd. delivered his valuable lectures in the 4th FINISHING SCHOOL TRAINING PROGRAMME of GNIPST. On 28th March, 2015 Dr. Gautam Chaterjee, an Alumni of Jadavpur University and presently associated with NIPER delivered his valuable lectures in the 5th FINISHING SCHOOL TRAINING PROGRAMME of GNIPST.


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On 11th April, 2015 the closing ceremony of the FINISHING SCHOOL TRAINING PROGRAMME was held in GNIPST Auditorium.

JOBS: All the students of Final Year B. Pharm and M. Pharm are hereby informed that an interview will be conducted on 23rd May, 2015 by Standard Pharmaceuticals Ltd. GSK for post: Production, QA, QC. All the students of Final Year B. Pharm and M. Pharm are hereby informed that an interview will be conducted by GSK for sales and marketing job. Details given below:

Date: 27.03.2015Time: 09:45 amVenue : GSK Consumer Healthcare Limited, Unit No. 208,

2nd Floor, Ecospace Campus B (3 B), New Town, Rajarhat, 24 Pgs (N). Kolkata-700156.

THYROCARE provisionally selected 15 students from JIS Group. Amongst these, 3 students of B. Sc (H) Biotechnology and M. Sc Biotechnology have been selected. Ipsita Mondal (M. Sc Biotechnology)Debriti Paul (M. Sc Biotechnology)Debopriya Chatterjee {B. Sc (H) Biotechnology}

The final year students of B.Pharm (31 students) and B.Sc (11 students) attended the pooled campus drive of Abbott India Ltd. on 10th March, 2015 at Jadavpur University. Among them 17 students have gone through to the final round of this pooled campus drive and short listed for final selection.

ACHIEVEMENT: Congratulations to Anurag Chanda, student of B.Pharm final year

who have got the 1st prize in poster presentation event in Prakriti 2015 at Department of Agricultural and Food engineering, IIT, Kharagpur.


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OTHERS: On 24th and 25th February, 2015 Swamiji of Gourio Mathwasdelivered some motivational lectuers in GNIPST.

The students of GNIPST participated in the 4th Sardar JodhSinghTrophy organised by NIT on 20th February, 2015. On 8th February, 2015 Gnipst celebrated the ReunionprogrammeReminiscence Reloaded 2015.

STUDENTS SECTION WHO CAN ANSWER FIRST????

Which compound was first synthesizedin 1910 by George Barger and James Ewens at Wellcome Laboratories in

London, England?

Answer of Previous Issues Questions: Lewis Carroll

Identify the person

Answer of Previous Issues Image: John tenniel


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Send your thoughts/Quiz/Puzzles/games/write-ups or any other contributions for Students Section& answers of this Section at [email protected] NOTE

It is a great pleasure for me to publish the 1st issue of 47th Volume of GNIPST BULLETIN. All the followers of GNIPST BULLETIN are able to avail the bulletin through facebook account GNIPST bulletin I am very much thankful to all the GNIPST members and readers who are giving their valuable comments, encouragements and supports. I am also thankful to Dr. Abhijit Sengupta, Director of GNIPST for his valuable advice and encouragement. Special thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar and Mr. Soumya Bhattacharya for their kind co-operation and technical supports. Thank you Mr. Soumya Bhattacharya for the questionnaires of the student section. An important part of the improvement of the bulletin is the contribution of the readers. You are invited to send in your write ups, notes, critiques or any kind of contribution for the forthcoming special and regular issue.

ARCHIVE The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15th June, 2012. The program started witha nice presentation by Dr. Pulok Kr. Mukherjee, School of NaturalProducts, JU on the skill to write a good manuscript forpublication in impact journals. It was followed by nearly two hourlong discussion among more than thirty participants on differentaspects of pharmacy education. Five nonmember participantsapplied for membership on that very day.


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GNIPST is now approved by AICTE and affiliated to WBUT forconducting the two years post graduate course (M.Pharm)in PHARMACOLOGY. The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to120.

AICTE has sanctioned a release of grant under ResearchPromotion Scheme (RPS) during the financial year 2012-13toGNIPST as per the details below:a. Beneficiary Institution: Guru Nanak Institution of PharmaceuticalScience & Technology.

b. Principal Investigator: Dr. LopamudraDutta.c. Grant-in-aid sanctioned:Rs. 16,25000/- only

d. Approved duration: 3 yearse. Title of the project: Screening and identification of potential

medicinal plant of Purulia & Bankura districts of West Bengal with respect to diseases such as diabetes, rheumatism, Jaundice, hypertension and developing biotechnological tools for enhancing bioactive molecules in these plants.

Activity Clubs of GNIPST: Name of Club Member Faculty SPORTS Mr. Debabrata GhoshDastidar LITERARY AND PAINTING Ms. Jeenatara Begum SCIENCE AND INNOVATIVE MODELLING

Mr. Samrat Bose

ECO Ms. Sumana Roy SOCIAL SERVICES Dr. Asis Bala PHOTOGRAPHY Ms. Sanchari Bhattacharya CULTURAL Ms. Priyanka Ray DEBATE AND EXTEMPORE Mr. Soumya Bhattacharya


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Louis Pasteur (1822 1895) Findings identify receptors modulating macrophage responses to spinal cord injury: 10th July, 2015A new studysheds light on opportunities to modulate macrophage responses after spinal cord injury, potentially reducing -- or even reversing -- damage and the resulting side effects. Using garlic to combat antimicrobial resistant urinary tract infections: 10th July, 2015Garlic extract may be an effective weapon against multi-drug resistant strains of pathogenic bacteria associated with urinary tract infections (UTI), according to a recent study. Ancestral diets determine vulnerability to type 2 diabetes: 10th July, 2015The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today's changing environment. New research reveals this may be a result of the nutrition endured by the... Role of microbiota in preventing allergies: 10th July, 2015The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. It is well established that a loss of bacterial symbionts promotes the development of allergies. Scientists have succeeded in explaining this pheno... Cell machinery wears complex coat: 10th July, 2015Detailed images have been produced of the intricate protein-coats that surround trafficking vesicles - the transport pods that move material around within biological cells. The study provides a new understanding of the complex machines that make up... License for cutting: How intracellular signaling regulates growth factor production: 10th July, 2015Cancer cells need life-essential molecules to proliferate. These so-called growth factors are activated by ectodomain shedding of precursor proteins on the outside of the plasma membrane, mainly carried out by three human cleavage enzymes. A pharmaceu... Risk of COPD may already occur in adolescence: 10th July, 2015Chronic obstructive pulmonary disease (COPD) is one of most common causes of death in the world today -- active smoking accounting for approximately 85 percent of all cases. Yet ground-breaking research indicates that accelerated decline of lung funct... No need to treat stable meniscus tears during ACL surgery: 10th July, 2015While athletes undergoing anterior cruciate ligament (ACL) surgery often have an additional meniscus injury, treating these tears at the same time may not be necessary. Research shows positive results for meniscal tears that were deemed stable and lef... Surgery may be best treatment option for multidirectional shoulder dislocations: 10th July, 2015While multidirectional instability of the shoulder has been traditionally treated without surgery, research shows that surgery is also effective for this type of dislocation. 'Jumping genes' may drive esophageal cancer: 10th July, 2015'Jumping genes' may add to the genetic chaos behind more than three-quarters of esophageal cancer cases, scientists have discovered. 'Jumping genes', called L1 elements, can uproot themselves and move to new areas in the DNA, sometimes accidentally mo...For detail mail to editor

KNOWLEDGE BASED ARTICLEGene therapy restores hearing in deaf mice Middle East respiratory syndrome coronavirus (MERS-CoV) The Philippines: 08th July, 2015On 6 July 2015, the IHR National Focal Point of the Philippines notified WHO of 1 laboratory-confirmed case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection.Read more FDA Approves Entresto (sacubitril/valsartan) for Heart Failure: 07th July, 2015The U.S. Food and Drug Administration today approved Entresto (sacubitril/valsartan) tablets for the treatment of heart failure. The drug has been shown to reduce the rate of cardiovascular death and hospitalization related to heart failure. CAMPUS NEWS STUDENTS SECTION

GNIPST Bulletin 47.1

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