Future Of Diagnostic Imaging

A Look Into The Next Decade

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(Part 4)

New “Eye” on The Body…

Excellent resolution for cancer detection, staging, management

> Good “Chemistry”…Specific markers for specific cancers

Cardiac and Neuro applications, too

Productivity…2X Info, 1/2 the time

Medicare Reimbursements ~$1,800

~30% AAGR Procedures (+150% in ’02)

> Studies approved… Expanding to Diagnosis, Staging, Re-Staging

> <1 Year ROI @ 5 Studies / Day

Key: Physician education / Referral

Registration of function (PET) onto exact anatomical map (CT)

Discovery ST

PET-CTApplication

Economics

Courtesy of Holy Name Hospital

Discovery ... “changed radiation treatment planning in 63% of the patients“Dizendorf, Univ. of Zurich: Diagnostic Imaging (Dec. 2001) – PET/CT Fusion Proves Its Worth

Discovery ... “changed radiation treatment planning in 63% of the patients“Dizendorf, Univ. of Zurich: Diagnostic Imaging (Dec. 2001) – PET/CT Fusion Proves Its Worth

Discovery… improving cancer treatment

Human Genome Discovery•‘88-’00: Mapped•‘98-’10: Analyzing SNP’s

Human Proteome Discovery‘00-’20: Discovering Protein Relationships to Genes

Genomics Development

Targeted ChemistryTargeted chemistry that binds to and highlight

biomarkers

Imaging TechnologiesHigh-sensitivity, high-resolution scanners

Disease Biomarkers identified from studies of the Human Genome & Proteome

• Detect Life Threatening Disease Before Symptoms Appear…Ex. Parkinson’s

• See Drugs Hitting Their Targets Almost Instantaneously

• Determine Patient Candidacy for Drugs

• Bring to Market Life Saving Drugs Tailored to Individual’s Genetic Make-up Faster

Preventive Medicine

Molecular Imaging