Pg 547 LDH converts pyruvate to lactate, restoring the pool of NAD +
Figure 7.6 Glycolysis Converts Glucose to Pyruvate.
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Transcript of Figure 7.6 Glycolysis Converts Glucose to Pyruvate.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
Ten enzymes catalyze ten reactions in turn.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
ATP transfers a phosphateto the 6-carbon sugar glucose.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
Glucose 6-phosphateis rearranged to formits isomer, fructose6-phosphate.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
A second ATPtransfers a phosphateto create fructose1,6-bisphosphate.
The fructose ring opens,and the 6-carbon fructose1,6-bisphosphate breaksinto the 3-carbon sugarphosphate DAP and itsisomer G3P.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
The DAP moleculeis rearranged to formanother G3P molecule.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
The two moleculesof G3P gain phosphategroups and are oxidized,forming two moleculesof NADH + H+ and twomolecules of1,3-bisphosphoglycerate(BPG).
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
The two molecules ofBPG transfer phosphategroups to ADP, formingtwo ATPs and two moleculesof 3-phosphoglycerate (3PG).
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
The phosphate groupson the two 3PGs move,forming two 2-phospho-glycerates (2PG).
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
The two molecules of2PG lose water, becomingtwo high-energy phospho-enolpyruvates (PEP).
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
Finally, the two PEPstransfer their phosphatesto ADP, forming two ATPsand two molecules ofpyruvate.
Figure 7.6 Glycolysis Converts Glucose to Pyruvate
Figure 7.6 Glycolysis Converts Glucose to Pyruvate