EXCITATION-CONTRACTION COUPLING IN SKELETAL, CARDIAC, AND SMOOTH MUSCLE

ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board:

NATHAN BACK, State University of New York at Buffalo

IRUN R. COHEN, The Weizmann Institute of Science

DAVID KRITCHEVSKY, Wistar Institute

ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research

RODOLFO PAOLETTI, University of Milan

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EXCITATION-CONTRACTION COUPLING IN SKELETAL, CARDIAC, AND SMOOTH MUSCLE

Edited by

George B. Frank University of Alberta Edmonton, Alberta, Canada

c. Paul Bianchi Thomas Jefferson University Philadelphia, Pennsylvania

and

Henk E. D. 1. ter Keurs University of Calgary Calgary, Alberta, Canada

Springer Science+Business Media, LLC

EXCITATION-CONTRACTION COUPLING IN SKELETAL, CARDIAC, AND SMOOTH MUSCLE

Edited by

George B. Frank University of Alberta Edmonton, Alberta, Canada

c. Paul Bianchi Thomas Jefferson University Philadelphia, Pennsylvania

and

Henk E. D. 1. ter Keurs University of Calgary Calgary, Alberta, Canada

Springer Science+Business Media, LLC

Llbrary of Congress Cataloglng-ln-Publlcatlon Data

Excitatlon-contraction coupling in skeletal, cardiac, and smooth muscle I edited by George B. Frank, C. Paul Bianchi, and Henk E.D.J. ter Keurs.

p. cm. -- (Advances in experimental medicine and biology ; v. 3111

"Proceedings of the Third International Symposium on Excitation -Contract ion Coupling in Skeletal, Cardiac, and Smooth Muscle, held June 26-30, 1991, in Banff, Alberta, Canada"--T.p. verso.

Includes bibliographical references and index. ISBN 0-306-44194-2 1. Muscle contraction--Congresses. 2. Calcium channels­

-Congresses. 3. Potassium channels--Congresses. 4. Excitation (Physiology)--Congresses. 1. Frank, George B. II. Bianchi, C. Paul (Carmine Pau]), 1927- III. ter Keurs, H. E. D. J. IV. International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle (3rd 1991 Banff, Alta.) V. Ser ies.

[DNLM, 1. Calcium Channels--physiology--congresses. 2. Muscle Contraction--drug effects--congresses. 3. Muscle, Smooth--drug effects--congresses. 4. Muscles--drug effects--congresses. ~1

AD559 v. 311 1992 I ~E 500 E96 1991] QP321.E93 1992 591. 1 '852--dc20 DNLM/DLC for Library of Congress 92-3573

CIP

Proceedings of the Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, held June 26-30, 1991, in Banff, Alberta, Canada

ISBN 978-1-4613-6483-2 ISBN 978-1-4615-3362-7 (eBook) DOI 10.1007/978-1-4615-3362-7

© 1992 Springer Science+Business Media New York Originally published by Plenum Press, New York in 1992 Softcover reprint of the hardcover 1 st edition 1992

AII rights reserved

No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher

PREFACE

The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E.DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction.

The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad. The foot structure is dependent upon a membrane bound calcium and binding site associated with the voltage sensor which upon release is involved in the charge transfer observed during excitation-contraction coupling. The single twitch and rapid discharge of calcium is dependent upon the feet-operated channels. However, when frequency of stimulation is increased, a second coupling mechanism which involves calcium influx through L-calcium channels and is related to the positive staircase and tetanus tension development. The concept of two parallel systems one involved in the single twitch and both involved in regulating force development as frequency of stimulation is increased.

Two predominant types of calcium release channels from the sarcoplasmic reticulum of striated, cardiac, and smooth muscles were discussed. The first type consists of a calcium release of calcium channel involved in rapid calcium release and the second, the IP3-operated channel which possesses much slower kinetics of calcium release and may involve depression of the calcium release of calcium channels allowing calcium-dependent functions of the cells to take place without necessarily involving contraction.

The ground work for advancing to a new level of understanding of excitation-contraction coupling in skeletal, cardiac, and smooth muscle was laid by the 3rd International Symposium on excitation-contraction coupling.

The Editors

CONTENTS

SPEAKERS

Na/Ca Exchange and First Messenger Ca in Skeletal Muscle Excitation-Contraction Coupling

Brian A. Curtis ........................................ 1

The Significance of Na+ in E-C Coupling in Muscle Vladimir Nesterov .................. . . .............. 19

Cellular Mg++ Accumulation is Altered by Extracellular Na+ and Directly Affects Agonist-Induced Mobilization of Ca++ in Vascular Smooth Muscle

SureV S. Shetty, John V. Zawadzki, and George 13. Weiss ........... 31

Calcium and Potassium Channel Regulation by Protein Phosphorylation in Smooth Muscle Cells of Guinea Pig Taenia Coli

Hideyo Yabu, Kazuo Obara, and Toshihiro Usuki

Potassium Channel Activation in Vascular Smooth Muscle G. Siegel, 1. Emden, K. Wenzel, J. Mironneau, and

........... 41

G. Stock ........ . . . . . . . . . . . . . . .. . ............. 53

Excitation- Contraction Coupling in Rat Skeletal Muscle Cells: Evolution during in vitro Myogenesis

Christian Cognard, Bruno Constantin, Michele Rivet, Nathalie 1mbert, Colette Besse, and Guy Raymond .............. 73

Volume Changes During Contraction of Isolated Frog Muscle Fibers

Stuart R. Taylor, Ian R. Neering, Laura A.Quesenberry, and V. Arlene Morris ................. 91

Analysis of Factors Involved in the Tissue Selectivity of Calcium Antagonists

Theophile Godfraind .................................. 103

vii

The Functional Role of T-Tubular Calcium Channels in Skeletal Muscle Contractions

George B. Frank and Murat Oz ......... . . . . . . . . . . . . . . .. 123

Effects of Calcium Release from the Sarcoplasmic Reticulum on Intramembrane Charge Movement in Skeletal Muscle

Laszlo Csernoch, Gonzalo Pizarro, Jesus Garcia, Geza Sziics, Enrico Stefani, and Eduardo Rios ............... . . . . . . . . . . . . . . . .. 137

Ca2+ Antagonists as Tools in the Analysis of Excitation-Contraction Coupling in Skeletal Muscle Fibres

H.Ch. Liittgau, Th. Bohle, and A. Schnier.. .................. 149

Regulation of Calcium Slow Channels in Cardiac Muscle and Vascular Smooth Muscle Cells

Nicholas Sperelakis, Noritsugu Tohse, and Yusuke Ohya .................. ................ 163

Subcellular Calcium Compartmentation and Exchange in the Cardiac Cell: Relation to Contractile Control

Glenn A. Langer and Terrell L. Rich ..... .

Calcium Release and Force Development in Rat Myocardium H.E.D.1. ter Keurs, P.H. Backx, H. Banijamali,

. . . . . . . . . .. 189

B. MacIntosh, and W.D. Gao .......................... 199

Potentiation of Contraction as Related to Changes in Free and Total Intracellular Calcium

Maria-Fiora Wendt-Gallitelli and Gerrit Isenberg .............. , ................... 213

Imaging of Calcium Transients during Excitation­Contraction Coupling in Skeletal Muscle Fibers

Julio Vergara and Marino DiFranco . . . . . . . .. . .............. 227

Role of Calcium Channels of the Sarcolemma and the Sarcoplasmic Reticulum in Skeletal Muscle Functions

C. Paul Bianchi ................... . ................ 237

Two Kinds of Calcium-Induced Release of Calcium from the Sarcoplasmic Reticulum of Skinned Cardiac Cells

Alexandre Fabiato ................ .

The Sarcoplasmic Reticulum of Skeletal Muscle: A Look from Inside

Pompeo Volpe, Adelina Martini, and

................. 245

Alessandra Nori .................................. 263

VUI

Ligand Binding and Cooperative Interactions among the Subunits of the Tetrameric Ca2+ Release Channel Complex of Sarcoplasmic Reticulum

Gerhard Meissner ... . . . . . . . . . . . ................. 277

Control of Calcium Release from the Sarcoplasmic Reticulum

G.D. Lamb and D.G. Stephenson ...... . ................. 289

Mechanisms of Calcium Release from Terminal Cisternae in Crustacean Muscle

Eduardo Rojas, Veronica Nassar-Gentina, Michael E. Pollard, and Mario Luxoro ................. 305

PRESENTERS

nACh Receptor-Activity Modulating Intracellular Ca2+ (RAMIe); Its Finding, Properties and Roles

I. Kimura,H. Tsuneki, T. Kondoh, and M. Kimura

Energetics of Muscarinic Stimulation of Smooth Muscle Robert M. Levin, Joseph Hypolite,

............... 319

Penelope A. Longhurst, and Alan J. Wein .. . ............. 323

NPY-(l8-36) and Pertussis Toxin Distinguish between the Negative and Positive Contractile Effects of Neuropeptide Y (NPY) in Ventricular Cardiomyocytes

B. Cherie Millar, Barbara J. McDermott, H. Michael Piper, Ambikaipakan Balasubramaniam, and Thomas Weis . . . . . . . . . . . . . . . . . . . ............. 325

Effect of Ryanodine on Glycerinated Rabbit Psoas Muscle Fibers

Takeshi Tsujimoto ................. .

Modulation of Ca2+ Release and Nat Channel Function in Skeletal Muscle by Fatty Acids

Jeffrey E. Fletcher, Steven J. Wieland, Jill Beech,

. .............. 327

Terry D. Heiman-Patterson, and Henry Rosenberg ............ 329

Effect of Free Radicals on Excitation-Contraction Coupling in Isolated Rat and Guinea Pig Ventricular Myocytes

Magda Horackova and Andrzej Beresewicz . . . . . . . . . . . . . . . 333

[Ca2+] and [Na+] in Rat Ventricular Myocytes Showing Negative and Positive Force Frequency Relationships

James E. Frampton, Simon M. Harrison, and Clive H. Orchard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335

IX

)(

Action of Vasoconstrictor Hormones and Calcium Entry Modulators on Electrical Activity and Intracellular Calcium of Smooth Muscle Cells

U.T. Ruegg, H.1. Knot, M.M. de Ree, and B.R.Gahwiler . . . . . . . . . . . . . . . . . . . ............. 337

Solubilization, Physiological Role and Localization of a Key Protein (31.5 KD) to Excitation-Contraction Coupling Process of Frog Skeletal Muscle Cells, Using Phenylglyoxal

S. Fujino, M. Fujino, K. Satoh, T. Nakai, T. Kado, T. Arima, and M. Fujino ........ .

GTPI'S Activates Calcium Channels in Neonatal Rat Ventricular Cells Q. Y. Liu, E. Karpinski, C.G. Benishin, and

. ..... 339

P.K.T.Pang ....... 0 0 0 • 0 •• 0 0 0 0 • 0 0 0 • 0 0 0 0 • 0 0 •••••• 0 341

Effects of Cyclopiazonic Acid, an Inhibitor of the Ca ++ ATPase of Sarcoplasmic Reticulum, on Ca + + Transport, Contraction and Relaxation in Cardiac Muscle

Philippe Lahouratate, Marie Josce Quiniou, and Claude Leoty . 0 • • 0 • • 0 • • • • 0 • 0 0 • 0 0 0 • • 0 0 • • 0 • 0 0 • 0 0 0 • • 343

Role of External Calcium and Sarcolemmal Na/Ca Exchange in the Depolarisation-Contraction Coupling in Mammalian Skeletal Muscle

Co Ruchet, Ao Elkhammari, 1. Noireaud, and C. Leoty 0 0 0 • 0 0 • 0 0 • 0 0 0 • 0 • 0 • o. 0 ••••• 0 • 0 0 0 0 •• 0 0 0 347

1P3 and GTPI'S Cause Contraction of Permeabilised Guinea Pig Ileum Longitudinal Smooth Muscle via Distinct Mechanisms

MoJ. Allen and 1.R. Carpenter . 0 •••• 0 0 •• o. " 0 ••••• 0 0 •• 0 0 0 351

Ag+ -Induced Inward Current on Frog Skeletal Muscle Takako Aoki and Toshiharu Oba . 0 • 0 •• 0 0 0 0 0 0 0 0 0 • 0 0 0 0 0 0 0 0 0 0 0 355

'Reverse Use-Dependent' Effects of 4-Aminopyridine on the Transient Outward Potassium Current in Ferret Right Ventricular Myocytes

Donald L. Campbell, Yusheng Qu, Randall L. Rasmusson, and Harold Co Strauss 0 0 0 • 0 0 • 0 0 0 • 0 0 0 0 0 357

Interaction of Ica with IN,dc, [Ca++]. and Ca++ Binding Proteins in Frog Atrium: A Theoretical Study

R.L. Rasmusson and DoL. Campbell . 0 0 0 •• 0 0 • 0 • 0 0 0 0 0 0 • 0 0 0 0 • 0 359

Evidence for the Existence of Endothelial Factors Regulating Contractility in Rat Heart

S. Winegrad, Go McClellan, and A. Weisberg .. 0 0 0 0 •• 0 0 0 ••• 0 0 0 0 363

Active and Passive Forces during Ischemia and Reperfusion of Rat Fast and Slow Twitch Skeletal Muscles

Andrew J. Carvalho and Nancy H. McKee ..................... 365

ciH Influx through Voltage- and Purinoceptor­Operated Channels Estimated from [Ca2+L Signals (Myocytes from Guinea-Pig Urinary Bladder)

G. Isenberg, V.Ya. Ganitkevich, and P. Schneider ................ 369

Calyculin A Modulates Voltage-Dependent Outward Current in Guinea-Pig Taenia Coli Smooth Muscle Cells

Kazuo Obara, Toshihiro Usuki, and Hideyo Yabu ................ 373

Excitation-Contraction Coupling in Canine Tracheal Smooth Muscle Cells

I.-P. Bourreau, C. Y. Kwan, and E.E. Daniel

Negative Inotropic Effects of Caffeine Related to

................. 375

Leak of Ca2+ from the Sarcoplasmic Reticulum B.R. MacIntosh ..................... . .............. 379

Endothelium-Dependent and - Independent Relaxation of Aortas from Copper-Deficient Rats

Jack T. Saari . . . . . . . . . . . . . . . . . . . . . .. . .............. 381

Modulation of L-Type Calcium Current in Mammalian Ventricular Myocytes by Photolysis of Caged Calcium

Susan E. Bates and Alison M. Gurney ....................... 385

Effects of Inorganic Phosphate on Calcium and Tension Oscillations in Saponin-Treated Rat Cardiac Muscle

G.L. Smith. D.S. Steele, and C.A. Crichton .................... 387

Effects of Low Ionic Strength and Calmodulin on the Decline in Maximal Calcium-Activated Force in Permeabilized Smooth Muscle

C.A.Crichton and G.L. Smith ............................. 389

Correlation between the Results of Functional and Receptor Binding Studies in Cardiac Muscle

E. Fejer, 1. Szeredi, J. Gaa!, and P.Sz. Kormoczy ................ 391

Pulmonary Beta Receptor Number Changes under the Influence of Ovalbumin Sensitization and Glucocorticoid Treatment

P.Sz. Kormoczy, M. Szabo, 1. Gaal, and E. Fejer . . . . . . . . . . . . . . . . 393

xi

Role of Guanylate Cyclase Activation in the Smooth Muscle Actions of Dihydropyridines

Christopher R. Triggle, Sean O'Neill, and D. Bieger ...................................... 395

a-Mediated Vasoconstriction: Transmembrane Signalling and Receptor Reclassification

C.R. Triggle and R. Tabrizchi ....... .

The Effects of Changes in p02 on Endothelium-Dependent and -Independent Relaxations of the Human Umbilical Artery and Rat Aorta

. ............ 397

Hui Xie and Christopher R. Triggle ......................... 399

Ca Ions and Potassium Contracture in the Retractor Unguis Muscle of the Cockroach

Toshio Yamaguchi, Hiroshi Washio, and Yusuke Kato ............. 401

Sphingosine Inhibits Calcium Release from Sarcoplasmic Reticulum Mcmbranes

R. Betto, A. Teresi, G. Fachechi-Cassano, G. Salviati, and R.A. Sabbadini . . . . . ............... 403

Purification of a Ryanodine-Sensitive Channel Protein from Human Neutrophils

David P. Rardon and Philip C. Krause .... . ............... 405

Regulation of Smooth Muscle Contraction by the Myosin Light Chain Phosphorylation-Dependent and -Independent Mechanisms

H. Karaki, M. Hori, K. Sato, H. Ozaki, H. Takano-Ohmuro, T. Tsuchiya, and H. Sugi ............... 407

Calcium Release Channel of Sarcoplasmic Reliculum: An Important Target for Doxorubicin-Mediated Cardiotox ici ty

Isaac N. Pessah ................... . . . . . . . . . . . . . . . 409

Calcium or Sodium Leakage Channels in Cultured Mammalian M yotubes

C.G. Carlson and Y. Feng .............................. 411

Citrate Decreases Ca Current and Changes Selectivity of Cardiac Ca Channels

Larry V. Hryshko and Donald M. Bers .................. 413

Effects on Ca2+ Uptake of Monoclonal Antibodies Raised against Canine Cardiac Phospholamban and their Correlation with Epitopic Location

Gary L. Morris and J.H. Wang ............................ 417

~11

4'iCa + + Efflux Studies in Rabbit T -Tubule Membrane Preparations in the Range of Late After Potentials during Tetanic Contractions

A.M. OZ, S.M.J. Dunn, and G.B. Frank.. . .................. 419

Biochemical Properties of OR-1259 - A Positive Inotropic and Vasodilatory Compound with an Antiarrhythmic Effect

Atso Raasmaja, Antti Talo, Heimo Haikala, Erkki Nissinen, Inge-Britt Linden, and Pennti Pohto . . . . . . . . . . . . . . . .. . .................. 423

Characterization of a Muscle Membrane ATPase Glycoprotein

P.J. Yazaki, H.B. Cunningham, J.J. Kang, C. Jachec, S.A. Hunt, R.C. Domingo, R.A. Sabbadini, and A.S. Dahms. . . . . ................ 425

Role of Protein Kinase C (PKC) in Mediating Ca2+ Entry in Vascular Smooth Muscle Cells

Y.T. Xuan, O.L. Wang, and A.R. Whorton ................. 427

Postganglionic Nicotinic Action of Anatoxin-A on Guinea Pig Ileum Antagonized by Thymopentin

Peter K. Chiang, 1. Katzhendler, Richard K. Gordon, B.P. Doctor, and Nesbitt D. Brown ........ .

The Surface Input Site Responsible for Excitation-Contraction (E-C) Coupling Mechanism in Single Skeletal Muscle Fibres of Frog

M. Fujino, T. Arima, C. Hasegawa, K. Harano,

........... 429

M. Takahashi, S. Sano, and S. Fujino .. . ................ 431

Ca-Induced Ca Release from the SR of Barnacle Myofibrillar Bundles, Triggered by the Photorelease of Calcium Ions from Caged Calcium

T.J. Lea and c.c. Ashley . . . . . . . . . .................. 433

Contractile and Electrophysiologic Effects of Realkalization in Cardiac Tissues: Role of NalH Exchange and Increased rCa];

Jianmin Duan and Margaret P. Moffat ..... ................. 435

Leukotriene-Induced Contraction of Isolated Guinea Pig Gallbladder (OB) Strips

Stephen M. Freedman, Debesh K. BasLl, John L. Wallace, and Eldon A. Shaffer . . . . . . . . . . . . . . . . . . . . 437

xiii

XIV

Effects of Ryanodine on SR Ca2 + Release Channels Demonstrated with Caffeine-Induced Tension Transients in Skinned Striated and Vascular Smooth Muscle

Judy Y. Su ........ . . . . . . . . . . . . .. . ............... 439

Effects of Diaphragmatic Fatigue on Phosphoinositide Hydrolysis

W.McD. Anderson, J.H. Zavecz, and P. Tso ................ 445

Physiological Role and Localization of the New Ouabain Receptor Protein (31.5 KD) from Cat Cardiac Muscles, Using the Monoclonal AB against the Protein

Masako Fujino, Sumiko Fujino, Kumi Satoh, Tohru Nakai, and Tetsuo Kado ...... . ................ 449

Na-Ca Exchange Current During the Cardiac Action Potential

Glenna Bett, Denis Noble, Susan Noble, Yung Earm, Won-Kyung Ho, and In-Suk So .......... .

Author Index

Subject Index

453

455

459