Evaluating Feline Pruritus -
Transcript of Evaluating Feline Pruritus -
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PetsLivingLonger.com
Keith A Hnilica DVM, MS, MBADiplomate ACVD
[email protected](865) 405-4203
Evaluating Feline Pruritus
What's the problem?Cats are not small dogs…Differentials for feline pruritusDifferentials for feline pruritus.A dermatologists approach…
CookbookMethodical
Evaluating Feline Pruritus
Distinct Clinical Syndromes?Miliary DermatitisAllergic Alopecia - PruritusAllergic Alopecia PruritusEosinophilic Granuloma Complex"Head and Neck Pruritus"
All have similar etiologiesSimilar diagnostic strategySimilar therapeutics
Evaluating Feline PruritusFleas
Fleas Fleas
Food allergyAtopyContact DermatitisPyodermaMalasseziaMites
Demodex gatoiOtodectesCheyletiellaNotoedres
Insect HypersensitivityMosquitoesMoth, CockroachFlies
MalasseziaDermatophytosisDrug ReactionParaneoplasticPemphigusMycosis FungoidesPsychogenicHerpes VirusFeLV/FIVPapilloma virus
Miliary Dermatitis
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Managing Feline Pruritus
Cats only eat what THEY want.Cats are in touch with the inner barbarianbarbarian.Cats don't like pills.Cats don't like elixirs.Cats don't like water.Cat's remember!
Evaluating Feline Pruritus
Miliary dermatitis Allergic Alopecia Eosinophilic Granuloma
Miliary Dermatitis Feline Pruritic Syndrome
Allergic Alopecia Eosinophilic Granuloma Complex
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Eosinophilic Dermatoses Eosinophilic Dermatoses
Feline Idiopathic Ulcerative Dermatosis Plasma Cell Pododermatitis
Feline Idiopathic Ulcerative Dermatosis Evaluating Feline Pruritus
FleasFleas
Fleas
Food allergyAtopyContact DermatitisPyodermaMalasseziaMites
Demodex gatoiOtodectesCheyletiellaNotoedres
Insect HypersensitivityMosquitoesMoth, CockroachFlies
MalasseziaDermatophytosisDrug ReactionParaneoplasticPemphigusMycosis FungoidesPsychogenicHerpes VirusFeLV/FIVPapilloma virus
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Dogs follow the rules What to do?
Dr. Depo approach Evaluating Feline Pruritus
5 days post Depomedrol
When Steroids Go Bad - CatsDiabetesCorticoid-associated Congestive Heart Failure in 29 Cats. Smith SA, et al.
271 cats with CHF
29 with steroid administration in previous 90 days (11%)
VIN searchapx >30 cats with CHF after steroid administration
What to do?
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Cat Dermatitis: Easy or NOT
1. Eliminate fleasCapstar qod for 30 days
2. Ring worm
3 Eliminate mites3. Eliminate mitesRevolutionLime sulfur
4. Food trial
5. Cyclosporine
Hnilica itchnot.com
Managing Feline PruritusGo with the odds
FleasFleasFleasDemodexDemodexInsects/MitesFood
What to do? Eosinophilic Dermatoses
Evaluating Feline Pruritus
Ciba AH Novartis
http://www.cymedica.com
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The Life CycleWhat are MY dogs on??
Hnilica itchnot.com
What to do??
Identify what can be killed.
Evaluating Feline PruritusDTM Fungal Culture
Pruritus is variableDramatically different therapeutic planLi bilit f Z ti diLiability for Zoonotic disease
Bactilabs 1-800-227-7300
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What to do??? Evil Evil Creatures
Hartz Mountain
AVEHO
www.radil.missouri.edu
Novartis
Evaluating Feline Pruritus
Skin ScrapesTape prepFlea combFlea combVacuum
Feline Demodex
Demodex catiImmunosuppressionFeLV or FIV or steroids"Traditional Demodicosis"
Demodex gatoiContagiousPruriticSuperficial dweller
Demodex Gatoi
Feline Demodex gatoiClusters >> "Hot spots"Multiple cats in a homeCan be difficult to findon scrapesEasily treated
Lime sulfar dipsWeekly for 6-10 weeksAll cats in home
Demodex Gatoi
Lym Dyp trialTreat with 3 weekly dipsIf improved keep going for 6-10 p p g gtotalIf not improved pursue allergies
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Demodex Gatoi
MitesLime sulfar dipWeekly for 6-10 weeksSarcoptiform mitesDemodex gatoi
Evaluating Feline Pruritus
The FecalyzerR
Evaluating Feline Pruritus
Feline Demodex gatoiClusters >> "Hot spots"Multiple cats in a homeCan be difficult to findon scrapesEasily treated
Lime sulfur dipsDip Trial – weekly for 3 weeksWeekly for 6-10 weeksAll cats in home
What to do????
Evaluating Feline Pruritus
Feline allergic Dermatitis70% flea allergic17% food allergic17% food allergic
Variable response to steroids
13% atopic Good response to steroids
Chalmer s, Medleau L. Recognizing the signs of feline allergic dermatoses. Vet Med 1989.
Evaluating Feline Pruritus
Feline Food AllergyYear round pruritusAny of the 3 patternsAny of the 3 patternsVariable response to steroids10-30% with concurrent GI symptomsCommon offending proteins
Dairy, fish, beef, pork, chicken, rabbit, horse, lamb, eggs, clams, "commercial diets"
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Managing Feline PruritusDiagnosing food allergy
10 week food trialHome cooked
Cooked meatCooked meatPotato/rice
Canned foodInnovative Veterinary Diets (IVD)Green pea & duck/rabbitHills ZD???
No hunting!
Managing Feline PruritusFood
CannedBlend it
Rabbit/duckPotato
Real meat
Cats can commit foodacide.
What to do?????Cat Dermatitis: Easy or NOT
1. Eliminate fleasCapstar qod for 30 days
2. Ring worm
3 Eliminate mites3. Eliminate mitesRevolutionLime sulfur
4. Food trial
5. Cyclosporine
Hnilica itchnot.com
CyclosporineTacrolimus
Idiopathic Pruritus - Cyclosporine
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Eosinophilic Granuloma Stomatitis
D. Mawby
What to do?????
Eosinophilic Dermatoses Eosinophilic Dermatoses
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Evaluating Feline Pruritus
BiopsiesAt least 3 samplesSent to a dermatopathologistSent to a dermatopathologist
www.UTSkinVet.org
AllergicEosinophilsMast cells Autoimmune
AcantholysisNeoplasia
" Mr. Boo"
11 year old, MC, domestic short hairHypertension w/ II/VI systolic murmur
AmlodipineAmlodipineAtenolol
2 weeks durationAlopeciaIntense pruritus
" Mr. Boo" " Mr. Boo"
" Mr. Boo" " Mr. Boo"
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" Mr. Boo"Ultrasound revealed multiple nodules in the liver and spleen.
Cytology of aspirates: carcinoma
Owner elected euthanasia.
" Mr. Boo"Learning issue
Time reveals all.
If the world didn't suck we would all fall off.
jb
PetsLivingLonger.com
Keith A Hnilica DVM, MS, MBADiplomate ACVD
[email protected](865) 405-4203
"Daisy"3 year old, FS, domestic short hair2 year history of progressive alopecia
Licks all the timeLicks all the timePoor response to DepoMedrol
"Daisy" "Daisy"Cyclosporine
25mg/day on empty stomach6-8 weeks then taper
Macrolactam immunomodulators for topical treatment of inflammatory skin diseases.Bornhovd E et al. JAAD 2001.
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"Daisy"Learning issue
Never give up.