Euriso-top Stable Isotope complete catalogue

Parc des Algorithmes Bâtiment Homère Route de l’Orme 91194 Saint-Aubin cedexTél. : +33 (0) 1 69 41 95 96 Fax : +33 (0) 1 69 41 93 52

E-mail : [email protected] Website : http : // www.eurisotop.com

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Sta

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Isot

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® GmbH

Lebacher Strasse 4 D - 66005 Saarbrücken Tel.: + 49 (0) 681 99 63 338 Fax: + 49 (0) 681 99 63 438


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Parc des Algorithmes Bâtiment Homère Route de l’Orme 91194 Saint-Aubin cedex

Tél. : +33 (0) 1 69 41 95 96 Fax : +33 (0) 1 69 41 93 52


Introduction

Ordering Information

Packaging Information

Technical Information

Analytical Service & Custom Synthesis

1H: Chemical Shift

13C: Chemical Shift

15N: Chemical Shift

Research Compounds

Biomolecular NMR Products

Isotopic Gases

Isotopic Metals

Carbon-13 Breath Test Substrates Other In vivo Isotopic Tracers13CO2 Calibration Standards

NMR Deuterated Solvents

Please call sales office to request our catalog

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Lebacher Strasse 4 D - 66005 Saarbrücken Tel.: + 49 (0) 681 99 63 338 Fax: + 49 (0) 681 99 63 438


Stable isotope labelled compounds laboratory

EURISO-TOP®, a fully owned subsidiary of Cambridge Isotopes Laboratories (CIL) is pleased to introduce its new catalogue for Stable Isotope Labelled Compounds. For the past decade, EURISO-TOP® has been the leading European Producer of Deuterated Solvents and is unique in Europe as a supplier of the whole range of Stable Isotope Labelled Compounds.Due to our association with CIL, EURISO-TOP® is now able to offer customers a wider range of Research Compounds and Biomolecular NMR Products. Please note that the pro-ducts included in those two sections of this catalogue are produced by CIL.Strong emphasis is given to provide you with high quality products at reasonable prices with exceptional technical service and a quick product delivery.Our Quality Control is performed by NMR, MS, HPLC, GC, IR and UV instruments which provide technical data on our products.EURISO-TOP® is able to supply you with a permanent stock of more than 1000 products including Research Compounds, Isotopic Gases, Isotopic metals, In vivo Products and Biomolecular NMR Products.Our main target is to improve our partnership with our customers by responding to particular needs of researchers. EURISO-TOP® can assist you with your requirements for Custom Synthesis of new products. Please call us, we are ready to respond to your specific requests.

This catalogue includes a range of Stable Isotopes existing on the

market except for Deuterated Solvents which are in our specific Deuterated

Solvents catalogue.

Shipping and delivery

We generally ship our products in accordance with the least expensive carrier. The customer’s choice of carrier will be honoured whenever such means are appropriate.Delivery to the carrier shall be considered delivery to the customer.

Returns

Claims must be made within one month after receipt of the product.

Returns may be made within one month with the prior approval of EURISO-TOP®. We usually request the return of the original product. According to the technical data sheet, the buyer is responsible for approving the quality and the quantity of any product within the 30-days period stated above.

Discounts

Special prices will be quoted on request for large orders.

Placing an order

EURISO-TOP® Customer Service is open from 8:30 A.M. to 6:00 P.M.

Orders may be placed by fax : France/Export : + 33 (0) 1 69 41 93 52Germany : + 49 (0) 681 99 63 438

or by e-mail : France/Export : [email protected] + Austria : [email protected]

or website : http://www.eurisotop.com

Please provide the following information for the processing

of your order :

Your name, your phone and fax numbers, and user’s name, phone and fax numbers. Purchase order number. Shipping and invoicing addresses. EURISO-TOP® catalogue code and name of product. The VAT Number for European countries. Quantity and isotopic enrichment required. Catalogue price or EURISO-TOP® quotation number. Special instructions for packaging and/or shipping.

Conditions of sales

All prices are in Euros Ex-Works, and are exclusive of state or local taxes. All written quotations will be honoured for 30 days unless specified. For transport, see your EURISO-TOP® representative for appropriate princing. Freight and /or shipping charges could also be added depending on the order’s amount. Payment terms are net 30 days from date of invoice unless/ otherwise stated. There is a 1,3% per month (15,6% per annum) late charge after the first 30 days for late payment. Prices are subject to change without notice.

Ordering InformationIntroduction

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Technical InformationPackaging Information

Solid and liquid packaging

1/ sealed glass ampoules under inert atmosphere,2/ screw-cap glass vials,3/ vials “penicillin” type, with Teflon‚ faced rubber sealed

under inert atmosphere,4/ leak-tight cap polyethylene bottles.

Gases

Gases are usually provided in metal cylinders.Optional breakseal glass flasks may be chosen for quantities (one litre or less).For gases mixture, please contact our Customer Service.

modern physico-chemical facilities are available from our Analytical Service.Our policy is to co-operate fully with customers to make high quality pro-ducts available.We are continually improving tech-niques in order to provide you with the highest quality products.

a - Analysis by Nuclear Magnetic

Resonance (NMR)

Our 400MHz spectrometer is used by our Analysis Department to study : Isotopic enrichment measurements. Determination of labelled positions. Determination of chemical structures. Conformation studies of organic compounds. Chemical purity.

b - Analysis by Mass Spectrometry

We use a quadripole type mass spec-trometer. It allows electron impact, desorption (electron impact or chemi-cal ionisation) or FAB method.Additional accessory equipment enables analysis of solids, liquids and gases.It also allows the determination of the isotopic enrichment of labelled com-pounds, as well as the assignment or confirmation of their structure.

c - LAL test The research of bacteria endotoxin can be realised with the “Limulus Amaebocyte Lysate” (L.A.L.) test if requested by the customer.

Nomenclature

The nomenclature system used in this catalogue is the same as that accepted by the American Chemical Society and most scientific journals. The isotopic labeling pattern is placed in brackets and follows the product to which it refers.Ex : D-Glucose (U-13C6)“U” denotes uniform labelling at all appropriate atoms in the molecule. The abreviation N-t-Boc stands for tert-Butoxycarbonyl. The abreviation FMOC stands for Fluorenylmethoxycarbonyl.

Isotopic enrichment & chemical purity

a - Isotopic Enrichment

The isotopic enrichment of our labelled compounds is as high as possible and is carefully checked by Nuclear Magnetic Resonance (NMR), mass spectrometry or infrared spectroscopy.

b - Chemical Purity

The chemical purity secured is 98%+.The chemical purity of all our labelled compounds is carefully checked by gas or High Pressure Liquid Chromatography, Nuclear Magnetic Resonance spectroscopy, infrared or ultraviolet spectroscopy.

Quality control

Our purpose is to provide researchers with compounds of the highest standards of quality. To this end, EURISO-TOP® practises not only final product quality control but also quality control of raw materials. The most

Storage

Our products are non-radioactive and have a chemical stability comparable to their corresponding unlabelled com-pounds. Their storage is similar.

Handling

These products have nearly the same toxicity as unlabelled products and must be handled with care by trained personnel.To avoid isotopic contamination, of some products especially deuterated compound we handle them under inert atmosphere (nitrogen or argon).

Sterility-Pyrogenicity (S&P)

Some labelled compounds offered by EURISO-TOP® are S&P Tested.These products must be used under the sole responsibility of the purchaser.

Other Informations

Many of uniformly labelled amino acids, sugars and fatty acids are produced biosynthetically from various strains of Chlorella (blue-green algae).

The products are packaged according to their physical and chemical charac-teristics.We use the best available packaging materials to enable a simple and safe utilisation while preserving the quality of the products.Quality is carefully monitored during production and packaging, using instrumental analysis.We offer a large range of packaging options.We will try to accommodate special packaging request for a modest addi-tional fee. 04

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Analytical Service 1H Chemical Shift

Custom Synthesis

1H Nuclear Spin : 1/2 TMS = 0ppm

In addition to its catalogue, EURISO-TOP® can make cus-tom syntheses according to your needs and specifications. Our well-trained personnel, allied to a state-of-the-art equipment, enable us to synthesise very sophisticated com-pounds. Personal service is increased by direct communication between the customer and EURISO-TOP® Laboratory. Any information on the synthesis or purification of such a compound is kept strictly confidential. This service is par-ticularly appreciated by a great number of pharmaceutical companies.

Inquiries about special preparations should include :

Structural formula. Quantity. Isotopic enrichment. The necessary and/or acceptable positions of labelling.

O-OH Phenols-OH

-C-OH Alcohols-OH

-C-SH Thiolalcohols SH

-C-NH2 Amines-NH2

-COOH Carboxylic acids-OH

-CHO Aldehydes

Heteroaromatic

O Aromatic

≥ CH Alkenes

= CH2 Alkenes

HC-O- Alcohols Tertiary

-CH2-O- Alcohols Secondary

CH3-O- Alcohols Primary

Alkynes

> N-CH3

-S-CH3

O-CH3

-CO-CH2-

-CH2-

-CO-CH3

≥ C-CH3

X-C-CH3

Cyclopropyl

M-CH3 (M = Al, Li, Se, Si)

1212

1212

1111

1111

1010

1010

99

99

88

88

77

77

66

66

55

55

44

44

33

33

22

22

11

11

00

00

ppm (TMS)ppm (TMS)

ppm (TMS)ppm (TMS)

HPLC analysis

Our goal is to provide you with compounds of the highest standards of quality. To this end, EURISO-TOP® practises not only final product quality control but also QC of raw materials.We have the most modern physico-chemical instrumenta-tion in our Analytical Service. EURISO-TOP® can check for you the chemical purity of all labelled compounds using one or more of the following techniques : Gas Chromatography

or Liquid Chromatography, NMR spectroscopy and Mass Spectrometry and a variety of other analytical equipments to assist our quality control program.

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600 500 400 300 200 100 0ppm (CH3NO2)

600 500 400 300 200 100 0ppm (CH3NO2)

> N-C = C <

> N- Aliphatic Amines

> N < Aliphatic Ammonium Ions Enamines

= N < (1) Quadinines - N < (2)

> N-CO-N < Ureas

= N-CO- Amides

Thioureas

> N-CS- Thioamides

NO2 (1) Nitramines - N < (2)

Indoles, Pyrroles

= N - (1) Hydrazones - N < (2)

-C = N (1) Nitriles, Isonitriles - N = C (2)

> N = N (1) Diazo > N = N (2)

C-N = N (2) Diazonium C-N = N (2)

Pyridines

Imines

Oximes

Nitro

(1) (2)

(1) (2)

(1) (2)

(1) (2)

(1) (2)

(1) (2)

−

−

−

13C Nuclear Spin : 1/2 TMS = 0ppm

15N Nuclear Spin : 1/2 CH3NO2 = Oppm

220 200 180 160 140 120 100 80 60 40 20 0ppm (TMS)

220 200 180 160 140 120 100 80 60 40 20 0ppm (TMS)

F Cl Br I

F Cl Br I

-CHO Aldehyde

> C = O Ketone

-COOH Acid

Ester, Amide

Thioketone

> C = N- Azomethine

-C = N Nitrile

> C = N- Heteroaromatic

> C = C < Alkenes

> C = C < Aromatic

> C = C < Heteroaromatic

Alkynes

-C-C- (C Quaternary)

-C-O-

-C-N <

-C-S-

-C-Hal

> CH-C- (C Tertiary)

> CH-O-

> CH-N <

> CH-S-

> CH-Hal

CH2-C (C Secondary)

CH2-O-

CH2-N <

CH2-S-

CH2-Hal (C Primary)

H3C-C-

H3C-O-

H3C-N <

H3C-S-

H3C-Hal

−

15N : Chemical Shift13C : Chemical Shift

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ResearchCompounds

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R E S E A R C H C O M P O U N D S

ACLM-1160 Acetic Anhydride (2,2’-13C2, 99%) (*CH3CO)2O 0.25 g98006-45-2 CORROSive, FLAmmABLe LiquiD 0.5 g 1 g

CLM-1161 Acetic Anhydride (13C4, 99%) (*CH3*CO)2O 0.25 g114510-14-4 CORROSive, FLAmmABLe LiquiD 0.5 g 1 g

DLM-1162 Acetic Anhydride (D6, 98%) (CD3CO)2O 5 g16649-49-3 CORROSive, FLAmmABLe LiquiD

CNLM-3726 Acetaminophen (acetyl-13C2, 99% ; 15N, 98%) 1 g103-90-2fl

CLM-245 Acetone (2-13C, 99%) CH3*COCH3 0.5 g3881-06-9 1 g

CLM-1306 Acetone (1,3-13C2, 99%) *CH3CO*CH3 0.5 g7217-25-6 1 g

CLM-1334 Acetone (13C3, 99%) *CH3*CO*CH3 0.25 g93628-01-4 0.5 g 1 g

CLM-1260 Acetonitrile (1-13C, 99%) CH3*CN 0.5 g31432-55-0 1 g

CLM-1588 Acetonitrile (2-13C, 99%) *CH3CN 0.5 g1722-09-4 1 g

CLM-1242 Acetonitrile (13C2, 99%) *CH3*CN 0.25 g75-05-8fl 0.5 g 1 g

NLM-175 Acetonitrile (15N, 98%) CH3C*N 0.5 g14149-39-4

CLM-1584 Acetophenone (methyl-13C, 99%) C6H5CO*CH3 0.5 g71777-36-1 1 g

CLM-246 Acetyl Chloride (1-13C, 99%) CH3*COCl 1 g1520-57-6 FLAmmABLe LiquiD, CORROSive 5 g Stored in ampoules packaged under argon.

DLM-247 Acetyl Chloride (D3, 99%) CD3COCl 10 g19259-90-6 FLAmmABLe LiquiD, CORROSive Stored in ampoules packaged under argon.

CLM-703 Acetyl Chloride (2-13C, 99%) *CH3COCl 0.5 g14770-40-2 FLAmmABLe LiquiD, CORROSive 1 g Stored in ampoules packaged under argon.

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CLM-109 Acrylonitrile (1-13C, 99%) H2C=CH*CN 0.25 g107-13-1fl inhibited with 0.1% 4-methoxyphenol FLAmmABLe LiquiD, TOXiC

CLM-856 Acrylonitrile (13C3, 99%) H2*C=*CH*CN 0.1 g107-13-1fl inhibited with 0.1% 4-methoxyphenol FLAmmABLe LiquiD, TOXiC

CLM-115 DL-Alanine (2-13C, 99%) CH3*CH(NH2)COOH 0.25 g302-72-7fl 0.5 g

DLM-1276 DL-Alanine (2,3,3,3-D4, 97-98%) CD3CD(NH2)COOH 1 g53795-92-9

CLM-116 L-Alanine (1-13C, 99%) CH3CH(NH2)*COOH 0.5 g21764-56-7 1 g

CLM-2150 L-Alanine-N-t-BOC (1-13C, 99%) CH3CH(NH-t-BOC)*COOH 1 g15761-38-3fl

CLM-818 L-Alanine-N-FMOC (1-13C, 99%) CH3CH(NH-FMOC)*COOH 1 g35661-39-3fl

CLM-2016 L-Alanine (2-13C, 99%) CH3*CH(NH2)COOH 0.1 g62656-85-3 0.25 g 0.5 g

CLM-2011 L-Alanine-N-t-BOC (2-13C, 98-99%) CH3*CH(NH-t-BOC)COOH 0.25 g15761-38-3fl

CLM-3638 L-Alanine-N-FMOC (2-13C, 99%) CH3*CH(NH-FMOC)COOH 0.25 g35661-39-3fl

CLM-117 L-Alanine (3-13C, 99%) *CH3CH(NH2)COOH 0.5 g56-41-7fl 1 g

CLM-2151 L-Alanine-N-t-BOC (3-13C, 99%) *CH3CH(NH-t-BOC)COOH 0.5 g15761-38-3fl 1 g

CLM-1142 L-Alanine-N-FMOC (3-13C, 99%) *CH3CH(NH-FMOC)COOH 1 g35661-39-3fl

CLM-2734 L-Alanine (2,3-13C2, 99%) *CH3*CH(NH2)COOH 0.5 g56-41-7fl

CLM-3589 L-Alanine-N-t-BOC (U-13C3, 98%) *CH3*CH(NH-t-BOC)*COOH 0.25 g15761-38-3fl

DLM-248 L-Alanine (3,3,3-D3, 99%) CD3CH(NH2)COOH 1 g63546-27-0

DLM-2793 L-Alanine-N-t-BOC (3,3,3-D3, 99%) CD3CH(NH-t-BOC)COOH 1 g15761-38-3fl

DLM-250 L-Alanine (2,3,3,3-D4, 98%) CD3CD(NH2)COOH 0.1 g18806-29-6 1 g

Please inquire about quantity discountsfl CAS number of unlabeled compound Please inquire about quantity discounts fl CAS number of unlabeled compound


Catalog # Compound Formula AmountCAS #


O

NH

OH

***

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DLM-251 L-Alanine (D7,98%) CD3CD(ND2)COOD 1 g74280-71-0

NLM-454 L-Alanine (15N, 98%) CH3CH(*NH2)COOH 0.5 g25713-23-9 1 g

NLM-1903 L-Alanine-N-t-BOC (15N, 98%) CH3CH(*NH-t-BOC)COOH 0.25 g15761-38-3fl 0.5 g 1 g

NLM-614 L-Alanine-N-FMOC (15N, 98%) CH3CH(*NH-FMOC)COOH 1 g35661-39-3fl

CNLM-534 L-Alanine (U-13C3, 98% ; 15N, 98%) *CH3*CH(*NH2)*COOH 0.1 g56-41-7fl 0.25 g 0.5 g CNLM-2394 L-Alanine-N-t-BOC (U-13C3, 98% ; 15N, 98%) *CH3*CH(*NH-t-BOC)*COOH 0.05 g15761-38-3fl

CNLM-4355 L-Alanine-N-FMOC (U-13C3, 98% ; 15N, 98%) *CH3*CH(*NH-FMOC)*COOH 0.1 g35661-39-3 0.25 g

Algal Amino Acid Mixture see Biomolecular NmR Products

“Cell free” Amino Acid Mixture see Biomolecular NmR Products

2-AmiNOeTHANOL — See eTHANOLAmiNe

CLM-3971 α-Aminoisobutyric Acid (13C4, 99%) (*CH3)2*C(NH2)*COOH 0.1 g62-57-7fl

CLM-630 Aminopyrine (N,N-dimethyl-13C2, 99%) 1 g58-15-1fl (4-(Dimethylamino)antipyrine)

NN

O

C6H5

CH3

CH3(H3C)2N*

NLM-177 Ammonium Acetate (15N, 98%) CH3COO*NH4 1 g86451-35-6

DLM-1099 Ammonium Bromide (D4, 98%) ND4Br 5 g12265-06-4

DLM-1273 Ammonium Chloride (D4, 98%) ND4Cl 5 g12015-14-4 10 g

NLM-467 Ammonium Chloride (15N, 98% +) *NH4Cl 1 g39466-62-1 5 g

DLM-710 Ammonium Deuteroxide (D5, 99%) ND4OD 50 g12168-30-8 (26% solution in D2O) 100 g CORROSive (of soln.)

NLM-1320 Ammonium Hydroxide (15N, 98%) *NH4OH 5 g62948-80-5 (approximately 3.3N solution in H2O) (of soln.) CORROSive 15

NLM-711 Ammonium Nitrate (ammonium-15N, 98%) *NH4NO3 1 g31432-48-1 OXiDiZeR

NLM-712 Ammonium Nitrate (nitrate-15N, 98%) NH4*NO3 1 g31432-46-9 OXiDiZeR

NLM-390 Ammonium Nitrate (15N2, 98%) *NH4*NO3 1 g961-07-9fl OXiDiZeR

DLM-1100 Ammonium Sulfate (D8, 98%) (ND4)2SO4 5 g13814-01-2 10 g

NLM-713-10 Ammonium Sulfate (15N2, 10%) (*NH4)2SO4 50 g43086-58-4

NLM-713 Ammonium Sulfate (15N2, 98% +) (*NH4)2SO4 1 g43086-58-4

CLM-714 Aniline (13C6, 99%) *C6H5NH2 0.1 g100849-37-4 TOXiC 0.25 g

DLM-862 Aniline (ring-D5, 98%) C6D5NH2 1 g4165-61-1 TOXiC 5 g

DLM-106 Aniline (D7, 98%) C6D5ND2 5 g14545-23-4 TOXiC

NLM-1314 Aniline (15N, 98%) C6H5*NH2 1 g7022-92-6 TOXiC

CNLM-4805 Aniline (13C6, 98% ; 15N, 98%) *C6H5*NH2 on request62-53-3fl TOXiC

CLM-715 D-Arabinose (1-13C, 99%) HOCH2(CHOH)3*CHO 0.25 g 70849-23-9 0.5 g 1 g

CLM-1288 D-Arabinose (2-13C, 98%) HOCH2(CHOH)2(*CHOH)CHO 0.25 g10323-20-3fl 0.5 g 1 g

DLM-1233 Arachidic Acid (D39, 98%) CD3(CD2)18COOH 1 g506-30-9fl

CLM-2265 L-Arginine•HCl (U-13C6, 98%) H2N*C(=NH)NH(*CH2)3*CH(NH2)*COOH•HCl 0.1 g 1119-34-2fl (may contain < 5% D-isomer) 0.25 g 0.5 g

NLM-395 L-Arginine•HCl (guanido-15N2, 98%) H2*NC(=*NH)NH(CH2)3CH(NH2)COOH•HCl 0.5 g204633-92-1 1 g

NLM-396 L-Arginine•HCl (U-15N4, 98%) H2*NC(=*NH)*NH(CH2)3CH(*NH2)COOH•HCl 0.1 g 1119-34-2fl

NLM-1264 L-Arginine-N-FMOC, PMC (U-15N4, 98%) PMC*NHC(=*NH)*NH(CH2)3CH(*NH-FMOC)COOH 0.1 g119831-72-0fl


Please inquire about quantity discounts fl CAS number of unlabeled compoundPlease inquire about quantity discountsfl CAS number of unlabeled compound



16


CNLM-539 L-Arginine•HCl (U-13C6, 98% ; U-15N4, 98%) H2*N*C(=*NH)*NH(*CH2)3*CH(*NH2)*COOH•HCl 0.1 g 1119-34-2fl (may contain < 5% D-isomer) 0.25 g 0.5 g

CNLM-4226 L-Arginine-N-FMOC, PMC (5%D) PMC*NH*C(=*NH)*NH(*CH2)3*CH(*NH-FMOC)*COOH 0.1 g 119831-72-0fl (U-13C6, 98% ; U-15N4, 98%) (may contain <5% D-isomer)

NLM-120 L-Asparagine•H2O (amide-15N, 98%) H2*NCOCH2CH(NH2)COOH•H2O 0.25 g5794-13-8fl 0.5 g

NLM-3286 L-Asparagine•H2O (15N2, 98%) H2*NCOCH2CH(*NH2)COOH•H2O 0.25 g5794-13-8fl 0.5 g

NLM-4204 L-Asparagine-α-FMOC, N-β-Trityl (C6H5)3C*NHCOCH2CH(*NH-FMOC)COOH 0.1 g132388-59-1fl (15N2, 98%) Special shipping requirements may apply. Please inquire at the time of order.

CNLM-3819 L-Asparagine•H2O H2*N*CO*CH2*CH(*NH2)*COOH•H2O 0.1 g5794-13-8fl (U-13C4, 98% ; U-15N2, 98%) 0.25 g 0.5 g

CNLM-4354 L-Asparagine-N-FMOC H2*N*CO*CH2*CH(*NH-FMOC)*COOH on request71989-16-7fl (U-13C4, 98% ; U-15N2, 98%) CNLM-6193 L-Asparagine-N-α-FMOC, N-β-Trityl (C6H5)3C*NH*CO*CH2*CH(*NH-FMOC)*COOH 0.1 g132388-59-1fl (U-13C4, 98% ; U-15N2, 98%) Special shipping requirements may apply. Please inquire at the time of order.

CLM-3616 L-Aspartic Acid (1-13C, 99%) HOOCCH2CH(NH2)*COOH on request81201-97-0

CLM-627 L-Aspartic Acid (3-13C, 99%) HOOC*CH2CH(NH2)COOH 0.05 g56-84-8fl 0.1 g 0.25 g CLM-4455 L-Aspartic Acid (1,4-13C2, 99%) HOO*CCH2CH(NH2)*COOH 0.5 g56-84-8fl

CLM-1801 L-Aspartic Acid (U-13C4, 98%) HOO*C*CH2*CH(NH2)*COOH 0.25 g56-84-8fl 0.5 g 1 g

CLM-4249 L-Aspartic Acid-N-α-CBZ (U-13C4, 95%) HOO*C*CH2*CH(NH-CBZ)*COOH 0.1 g1152-61-0fl

DLM-546 L-Aspartic Acid (2,3,3-D3, 98%) HOOCCD2CD(NH2)COOH 0.1 g3842-25-9 0.25 g

NLM-718 L-Aspartic Acid (15N, 98%) HOOCCH2CH(*NH2)COOH 0.5 g3715-16-0 1 g

NLM-3493 L-Aspartic Acid-N-t-BOC (15N, 98%) HOOCCH2CH(*NH-t-BOC)COOH 1 g13726-67-5fl 17

NLM-1908 L-Aspartic Acid-N-t-BOC, β-Benzyl Ester C6H5CH2OOCCH2CH(*NH-t-BOC)COOH 0.25 g7536-58-5fl (15N, 98%) CNLM-544 L-Aspartic Acid (U-13C4, 98% ; 15N, 98%) HOO*C*CH2*CH(*NH2)*COOH 0.25 g56-84-8fl 0.5 g 1 g

CNLM-2392 L-Aspartic Acid-N-t-BOC, C6H5CH2OO*C*CH2*CH(*NH-t-BOC)*COOH 0.05 g 7536-58-5fl ß-Benzyl Ester (U-13C4, 98% ; 15N, 98%)

BCLM-466 Barium Carbonate (13C, 99%) Ba*CO3 5 g51956-33-3 TOXiC

CLM-721 Benzaldehyde (carbonyl-13C, 99%) C6H5*CHO 0.5 g10383-90-1 inhibited with 0.1% hydroquinone. 1 g miSCeLLANeOuS HAZARDOuS GOOD

CLM-180 Benzaldehyde (ring-13C6, 99%) *C6H5CHO 0.5 g100-52-7fl inhibited with 0.1% hydroquinone. miSCeLLANeOuS HAZARDOuS GOOD DLM-465 Benzaldehyde (ring-D5, 98%) C6D5CHO 5 g14132-51-5 inhibited with 0.1% hydroquinone. miSCeLLANeOuS HAZARDOuS GOOD

DLM-396 Benzaldehyde (D6, 98%) C6D5CDO 5 g17901-93-8 inhibited with 0.1% hydroquinone. miSCeLLANeOuS HAZARDOuS GOOD

NLM-255 Benzamide (15N, 98%) C6H5CO*NH2 1 g31656-62-9

CLM-182 Benzene (13C6, 99%) *C6H6 0.1 g32488-44-1 0.5 g

DLM-733 Benzene (1,3,5-D3, 98%) C6H3D3 5 g1684-47-5

CLM-657 Benzoic Acid (carboxyl-13C, 99%) C6H5*COOH 1 g3880-99-7 5 g

CLM-1813 Benzoic Acid (ring-13C6, 99%) *C6H5COOH 0.5 g65-85-0fl

DLM-122 Benzoic Acid (ring-D5, 98%) C6D5COOH 1 g1079-02-3 5 g

CLM-3253 Benzophenone (carbonyl-13C, 99%) C6H5*COC6H5 0.5 g32488-48-5

DLM-183 Benzophenone (D10, 98%) C6D5COC6D5 5 g22583-75-1





18


DLM-1663 1,4-Benzoquinone (D4, 98%) 1 g106-51-4fl (Quinone) TOXiC

OO

CLM-1583 Benzyl Alcohol (α-13C, 99%) C6H5*CH2OH 0.5 g54522-91-7 1 g

DLM-407 Betaine (D11, 98%) (CD3)3N+CD2COO- 1 g107-43-7fl (Trimethylglycine)

Bio-Express see Biomolecular NmR Products

DLM-494 Biphenyl (D10, 98%) C6D5C6D5 1 g1486-01-7 (Diphenyl) 5 g

DLM-2004 Bis (2-Chloroethyl) Ether (D8, 98%) CICD2CD2OCD2CD2CI 0.05 g11-44-4fl 0.1 g

DLM-2775 Bisphenol A (propane-D6, 98%) 0.1 g80-05-7fl 1 g

HO OH

CD3D3C

DLM-1540 Bisphenol A (ring-D8, 98%) (CH3)2C(C6D4OH)2 0.5 g80-05-7fl

DLM-1839 Bisphenol A (D16, 98%) (CD3)2C(C6D4OD)2 1 g80-05-7fl

DLM-4528 Bis-Tris (D19, 98%) (DOCD2CD2)2NC(CD2OH)3 0.5 g6976-37-0fl 1 g

N-t-BOC PROTeCTeD AmiNO ACiDS — See LiSTiNGS OF iNDiviDuAL AmiNO ACiDS

CLM-723 Bromoacetic Acid (1-13C, 99%) BrCH2*COOH 1 g57858-24-9 CORROSive 5 g

CLM-724 Bromoacetic Acid (2-13C, 99%) Br*CH2COOH 1 g64891-77-6 CORROSive 5 g

CLM-871 Bromobenzene (13C6, 99%) *C6H5Br 0.5 g108-86-1fl FLAmmABLe LiquiD

DLM-398 Bromobenzene (D5, 99%) C6D5Br 5 g4165-57-5 FLAmmABLe LiquiD 10 g 25 g

DLM-1169 1-Bromobutane (D9, 96-98%) CD3(CD2)3Br 5 g109-65-9fl (Butyl Bromide) FLAmmABLe LiquiD

DLM-3097 1-Bromodecane (D21, 98%) CD3(CD2)9Br 1 g112-29-8fl (Decyl Bromide)

DLM-1980 1-Bromododecane (D25, 98%) CD3(CD2)11Br 1 g143-15-7fl DLM-874 Bromoethane (D5, 98%) CD3CD2Br 10 g3675-63-6 TOXiC

19

CLM-875 2-Bromoethanol (13C2, 99%) Br(*CH2)2OH 0.25 g84508-51-0 Chemical Purity : 95% TOXiC

DLM-103 2-Bromoethanol (1,1,2,2-D4, 98%) Br(CD2)2OH 1 g865-50-9 Chemical Purity : 95% 5 g TOXiC

DLM-400 Bromoform (D, 99.5%) CDBr3 10 g2909-52-6 Stabilized with copper wire. 25 g TOXiC

DLM-1922 n-Butanol (D9, 98%) CD3(CD2)3OH 1 g71-36-3fl FLAmmABLe LiquiD 5 g

DLM-1598 n-Butanol (D10, 98%) CD3(CD2)3OD 5 g34193-38-9 FLAmmABLe LiquiD

DLM-1109 tert-Butanol (OD, 99%) (CH3)3COD 25 g3972-25-6fl (2-Methyl-2-propanol) 100 g (anhydrous) FLAmmABLe LiquiD

DLM-1358 tert-Butanol (D9, 98%) (CD3)3COH 5 g75-65-0fl FLAmmABLe LiquiD

DLM-1664 tert-Butanol (D10, 98%) (CD3)3COD 5 g53001-22-2 FLAmmABLe LiquiD

DLM-1508 Butyric Acid (D7, 98%) CD3(CD2)2COOH 5 g107-92-6fl CORROSive

BuTyRiC ACiD, SODium SALT — See SODium BuTyRATe

CCLM-728 Caffeine (3-methyl-13C, 99%) 0.5 g58-08-2fl

CLM-514 Caffeine (trimethyl-13C3, 99%) *C3C5H10N4O2 1 g58-08-2fl

CNLM-333 Caffeine (2-13C, 99% ; 1,3-15N2, 98%) *CC7H10*N2N2O2 0.1 g58-08-2fl

NLM-499 Calcium Nitrate (15N2, 98%) Ca(*NO3)2 1 g10124-37-5fl OXiDiZeR

CAPRIC ACID — SEE DECANOIC ACID

CAPROIC ACID — SEE HEXANOIC ACID





N

N N

N

O

O

H3C

CH3

CH3

32

1

20


CLM-879 Carbon (12C, 99.93%) *C 1 g7440-44-0 (13C depleted) 5 g (amorphous)

CLM-402 Carbon (13C, 99%) *C 1 g14762-74-4 Chemical Purity : 97% 10 g (amorphous)

CLM-730 Carbon Disulfide (13C, 97-99%) *CS2 0.5 g30860-31-2 (Supplied in glass ampoules) 1 g FLAmmABLe LiquiD, TOXiC Air freight forbidden.

CLM-731 Carbon Tetrachloride (13C, 99%) *CCl4 0.1 g32488-50-9 0.5 g 1 g CLM-804 Cholesterol (3,4-13C2, 99%) *C2C25H46O 0.1 g7887-48-6

DLM-2607 Cholesterol (2,2,3,4,4,6-D6, 97-98%) C27H40D6O 0.1 g57-88-5fl

DLM-3057 Cholesterol (25,26,26,26,27,27,27-D7, 98%) C27H39D7O 0.1 g57-88-5fl

CLM-2710 Cholic Acid (24-13C, 99%) 0.1 g52886-36-9 0.5 g

HO

COOH

H

H H

24

HOH

OH

DLM-3015 Choline Bromide (D13, 98%) HO(CD2)2N(CD3)3Br 0.1 g1927-06-6fl 0.5 g

DLM-549 Choline Chloride (trimethyl-D9, 98%) HO(CH2)2N(CD3)3Cl 1 g67-48-1fl

DLM-3487 Citric Acid (2,2,4,4-D4, 98%) HOOCCD2C(OH)(COOH)CD2COOH0 on request77-92-9fl CORROSive

CLM-4899 L-Citrulline (ureido-13C, 99%) on request372-75-8fl (L-2-amino-5-ureidovaleric acid) H2N*CONH(CH2)3CH(NH2)COOH

DLM-2057 Cortisol (9,12,12-D3, 98%) 0.01 g 115699-92-8 (Hydrocortisone)

O

HO

H

H H

HO COCH2OH

1112

9

DLM-2218 Cortisol (9,11,12,12-D4, 98%) C21,H26D4O5 0.01 g 50-23-7fl (Hydrocortisone) 21

DLM-192 Cyclohexanol (D12, 98%) C6D11OD 5 g66522-78-9 FLAmmABLe LiquiD

CLM-898 DL-Cysteine (3-13C, 99%) HS*CH2CH(NH2)COOH 0.5 g3374-22-9fl

CLM-1868 L-Cysteine (3-13C, 99%) HS*CH2CH(NH2)COOH 0.25 g52-90-4fl

CLM-2182 L-Cysteine, S-Benzyl (3-13C, 99%) C6H5CH2S*CH2CH(NH2)COOH 0.1 g

CLM-2403 L-Cysteine-N-FMOC, S-Benzyl (3-13C, 99%) C6H5CH2S*CH2CH(NH-FMOC)COOH 0.1 g53298-33-2fl

CLM-4320 L-Cysteine (U-13C3, 98%) HS*CH2*CH(NH2)*COOH on request52-90-4fl

DLM-769 L-Cysteine (3,3-D2, 98%) HSCD2CH(NH2)COOH 0.1 g52-90-4fl

DLM-4532 L-Cysteine, S-Trityl (3,3-D2, 98%) (C6H5)3CSCD2CH(NH2)COOH 0.1 g2799-07-7fl

NLM-2295 L-Cysteine (15N, 98%) HSCH2CH(*NH2)COOH 0.25 g52-90-4fl

NLM-3914 L-Cysteine, S-p-Methylbenzyl (15N, 98%) 0.1 g42294-52-0fl

NLM-3874 L-Cysteine-N-t-BOC, S-p-Methylbenzyl 0.25 g61925-77-7fl (15N, 98%)

NLM-3818 L-Cystine (15N2, 98%) [SCH2CH(*NH2)COOH]2 0.25 g56-89-3fl

CNLM-3871 L-Cysteine (U-13C3, 98% ; 15N, 98%) HS*CH2*CH(*NH2)*COOH 0.1 g52-90-4fl 0.25 g

CLM-520 L-Cystine (3,3-13C2, 99%) [S*CH2CH(NH2)COOH]2 0.25 g56-89-3fl

DDLM-133 n-Decane (D22, 99%) CD3(CD2)8CD3 1 g16416-29-8 FLAmmABLe LiquiD 5 g

DLM-2006 Decanoic Acid (methyl-D3, 98%) CD3(CH2)8COOH 0.5 g334-48-5fl (Capric Acid) 1 g





SCOOH

NH2*

SCOOH

NH-t-BOC*

22


DLM-270 Decanoic Acid (D19, 98%) CD3(CD2)8COOH 1 g88170-22-3

DLM-1002 n-Decanol (D21, 98%) CD3(CD2)9OH 1 g112-30-1fl

CLM-2122 2-Deoxy-D-glucose (6-13C, 99%) HO*CH2(CHOH)3CH2CHO 0.25 g154-17-6fl 0.5 g 1 g

CNLM-3752 4,6-Diamino-5-formamidopyrimidine 25 mg5122-36-1fl (formyl-13C, 98% ; diamino-15N2, 98%) (Fapyadenine)

N

N

O

HN

H2N

H2N

*

*

*

DLM-341 1,4-Dibromobenzene (D4, 98%) BrC6D4Br 5 g4165-56-4

DiCHLOROmeTHANe — See meTHyLeNe CHLORiDe

CLM-521 Diethyl Malonate (1,3-13C2, 99%) CH2(*COOCH2CH3)2 0.25 g105-53-3fl 0.5 g 1 g

1,4-DiHyDROXyBeNZeNe — See HyDROquiNONe

DiHyDROXyPHeNyLALANiNe — See L-DOPA

CLM-266 Dimethyl Sulfate (13C2, 99%) (*CH3)2SO4 1 g77-78-1fl Air freight forbidden.

DLM-1637 Dimethyl Sulfone (D6, 98%) (CD3)2SO2 1 g22230-82-6

DLM-2211 Diphenyl Ether (D10, 98%) C6D5OC6D5 0.1 g101-48-8fl

DLM-2622 DL-1,4-Dithiothreitol (D10, 98%) DSCD2CD(OD)CD(OD)CD2SD 0.5 g27565-41-9fl (DTT)

DLM-338 n-Dodecane (D26, 98%) CD3(CD2)10CD3 1 g16416-30-1 5 g

DODeCANOiC ACiD — See LAuRiC ACiD DLM-2274 Dodecylphosphocholine (D38, 98%) CD3(CD2)11OPO-

3CD2CD2N+(CD3)3 0.5 g

130890-78-7 (DPC)

DODeCyL SODium SuLFATe — See SODium DODeCyL SuLFATe

CLM-1007 L-Dopa (ring-13C6, 99%) 0.1 g59-92-7fl (3,4-Dihydroxyphenylalanine) DLM-2084 L-Dopa (ring-D3, 98%) (HO)2C6D3CH2CH(NH2)COOH 1 g53587-29-4 23

DLM-2724 n-Dotriacontane (D66, 98%) CD3(CD2)30CD3 1 g62369-68-0

EDLM-1008 Epichlorohydrin (D5, 98%) 1 g106-89-8fl TOXiC, FLAmmABLe LiquiD DLM-2866 DL-Epinephrine (α,α,β-D3, 97%) 0.01 g329-65-7fl 0.1 g

HO

OH

NH

HOD

DD

CLM-123 Erythromycin (N-methyl-13C, 99%) 1 g114-07-8fl

O

CH3

CH3H3C

C2H5

O

H3C

O

OHOH

H3C

CH3

OH

O

O

O

O CH3

HO

N

H3C CH3

OCH3

CH3

OH

CH3

CLM-165 Erythromycin, Lactobionate Salt 1 g3847-29-8fl (N-methyl-13C, 99%)

O

OOH

H

O

H

H

OHH

OH

CH2OH

H

CCHOH2C C C COOH

H H OH H

OHHOHO

CH3

CH3H3C

C2H5

O

H3C

O

OHOH

H3C

CH3

OH

O

O

O

O CH3

HO

N

H3C CH3

OCH3

CH3

OH

CH3

CLM-3758 Erythromycin, Lactobionate Salt *C2C47H89NO25 on request114-07-8fl (N,N-dimethyl-13C2, 90-95%)

CLM-803 Estradiol (3,4-13C2, 99%) on request50-28-2fl

HO

OH

H

H

H3

4

16

DLM-2487 Estradiol (2,4,16,16-D4, 95-97%) C18H20D4O2 5 mg50-28-2fl

CLM-673 Estrone (3,4-13C2, 90%) on request53-16-7fl

HO

O

H

H

H3

4

16

CLM-344 Ethanol (1-13C, 99%) CH3*CH2OH 0.5 g14742-23-5 (Ethyl Alcohol) (contains ≤ 5% H2O) 1 g FLAmmABLe LiquiD





NH2

COOHHO

HO

O

Cl

24


CLM-130 Ethanol (2-13C, 99%) *CH3CH2OH 0.5 g14770-41-3 (contains ≤ 5% H2O) 1 g FLAmmABLe LiquiD

CLM-551 Ethanol (13C2, 99%) *CH3*CH2OH 0.5 g70753-79-6 (contains ≤ 5% H2O) 1 g FLAmmABLe LiquiD

DLM-413 Ethanol (ethyl-D5, 98%) CD3CD2OH 5 g1859-08-1 (contains ≤ 5% H2O) FLAmmABLe LiquiD

CLM-3911 Ethanolamine•HCl (1-13C, 99%) HOCH2*CH2NH2•HCl 1 g2002-24-6fl CORROSive

CLM-274 Ethanolamine•HCl (1,2-13C2, 99%) HO*CH2*CH2NH2•HCl on request2002-24-6fl CORROSive

CLM-131 Ethyl Acetate (1-13C, 99%) CH3*COOC2H5 1 g3424-59-7 5 g

CLM-1121 Ethyl Acetate (2-13C, 99%) *CH3COOC2H5 1 g58735-82-3 5 g

CLM-1122 Ethyl Acetate (1,2-13C2, 99%) *CH3*COOC2H5 0.5 g84508-45-2 1 g

CLM-681 Ethyl Acetoacetate (3-13C, 99%) CH3*COCH2COOC2H5 0.5 g141-97-9fl 1 g CLM-522 Ethyl Acetoacetate (1,3-13C2, 99%) CH3*COCH2*COOC2H5 0.5 g141-97-9fl 1 g

CLM-523 Ethyl Acetoacetate (2,4-13C2, 99%) *CH3CO*CH2COOC2H5 0.5 g77504-74-6 1 g CLM-682 Ethyl Acetoacetate (3,4-13C2, 99%) *CH3*COCH2COOC2H5 0.25 g141-97-9fl 0.5 g 1 g

eTHyL ALCOHOL — See eTHANOL

DLM-199 Ethylbenzene (D10, 98%) C6D5CD2CD3 10 g25837-05-2

CLM-1010 Ethyl Bromoacetate (2-13C, 99%) Br*CH2COOCH2CH3 0.5 g85539-84-0 CORROSive 1 g Air freight forbidden.

CLM-1011 Eth yl Bromoacetate (1,2-13C2, 99%) Br*CH2*COOCH2CH3 0.5 g61898-49-5 CORROSive 1 g Air freight forbidden.

25

DLM-414 Ethylenediaminetetraacetic Acid (D12, 98%) [CD2N(CD2COOH)2]2 0.1 g60-00-4fl (EDTA) 0.5 g 1 g

DLM-3908 Ethylenediaminetetraacetic Acid (D16, 98%) [CD2N(CD2COOD)2]2 0.1 g60-00-4fl (EDTA) 0.5 g 1 g

DLM-3166 Ethylene Glycol (O,O-D2, 98%) DO(CH2)2OD 10 g2219-52-5

DLM-282 Ethyl Pyruvate (3,3,3-D3, 98%) CD3COCOOCH2CH3 0.5 g617-35-6fl 1 g

FCLM-4326 Fluorobenzene (13C6, 99%) *C6H5F 0.1 g462-06-6fl

FmOC PROTeCTeD AmiNO ACiDS — See LiSTiNGS OF iNDiviDuAL AmiNO ACiDS

FORmALDeHyDe — See PARAFORmALDeHyDe

CLM-806 Formaldehyde (13C, 99%) *CH2O 1 mL3228-27-1 (~20% w/w in H2O) (of soln.) FLAmmABLe LiquiD

DLM-1864 Formamide (D3, 98%) DCOND2 5 g43380-64-9

NLM-1516 Formamide (15N, 98%) HCO*NH2 1 g1449-77-0

CNLM-3858 5-Formamido-2,4-diamino-6-hydroxypyrimidine 25 mg51093-31-3fl (formyl-13C, 99% ; 4-amino-5-amido-15N2, 98%) (Fapyguanine) CLM-1284 Formic Acid (13C, 99%) H*COOH 0.5 g1633-56-3 (contains ≤ 5% H2O) 1 g CORROSive 5 g

DLM-285 Formic Acid (OD, 98%) HCOOD 5 g64-18-6fl (contains ≤ 5% D2O) CORROSive

DLM-286 Formic Acid (D2, 98%) DCOOD 5 g920-42-3 (contains ≤ 5% D2O) CORROSive

CLM-1201 D-Fructose (1-13C, 99%) HOCH2(CHOH)3CO*CH2OH 0.25 g108311-21-3 0.5 g 1 g





26


CLM-1527 D-Fructose (2-13C, 99%) HOCH2(CHOH)3*COCH2OH 0.25 g57-48-7fl 0.5 g 1 g

CLM-1553 D-Fructose (U-13C6, 99%) HO*CH2(*CHOH)3*CO*CH2OH 0.25 g57-48-7fl 0.5 g 1 g

CLM-1529 Fumaric Acid (13C4, 99%) 0.1 g110-17-8fl

HOOCCOOH

DLM-1539 Fumaric Acid (2,3-D2, 98%) HOOCCD=CDCOOH 5 g244661-32-3

GCLM-744 D-Galactose (1-13C, 99%) HOCH2(CHOH)4*CHO 0.25 g70849-30-8 0.5 g 1 g

CLM-745 D-Galactose (2-13C, 99%) HOCH2(CHOH)3(*CHOH)CHO 0.25 g59-23-4fl 0.5 g 1 g

CLM-420 D-Glucose (1-13C, 99%) HOCH2(CHOH)4*CHO 0.25 g40762-22-9 Significant discounts are available 0.5 g for larger quantities. 1 g

CLM-746 D-Glucose (2-13C, 99%) HOCH2(CHOH)3(*CHOH)CHO 0.25 g105931-74-6 0.5 g 1 g

CLM-1393 D-Glucose (3-13C, 99%) HOCH2(CHOH)2(*CHOH)(CHOH)CHO 0.25 g101615-88-7 0.5 g 1 g CLM-1394 D-Glucose (4-13C, 99%) HOCH2(CHOH)(*CHOH)(CHOH)2CHO 0.25 g84270-10-0 0.5 g 1 g

CLM-1395 D-Glucose (5-13C, 99%) HOCH2(*CHOH)(CHOH)3CHO 0.25 g120388-24-1 0.5 g 1 g

CLM-481 D-Glucose (6-13C, 99%) HO*CH2(CHOH)4CHO 0.25 g70491-70-2 0.5 g 1 g CLM-504 D-Glucose (1,2-13C2, 99%) HOCH2(CHOH)3(*CHOH)*CHO 0.25 g138079-87-5 0.5 g 1 g 27

CLM-1396 D-Glucose (U-13C6, 99%) HO*CH2(*CHOH)4*CHO 0.25 g110187-42-3 Significant discounts are available 0.5 g for larger quantities. 1 g

DLM-1150 D-Glucose (1-D, 98%) HOCH2(CHOH)4CDO 0.25 g106032-61-5 0.5 g 1 g

DLM-1271 D-Glucose (2-D, 98%) HOCH2(CHOH)3(CDOH)CHO 0.25 g106032-60-4 0.5 g 1 g DLM-349 D-Glucose (6,6-D2, 99%) HOCD2(CHOH)4CHO 1 g18991-62-3 Significant discounts are available 5 g for larger quantities. 10 g

DLM-2062 D-Glucose (1,2,3,4,5,6,6-D7, 98%) HOCD2(CDOH)4CDO 0.5 g66034-51-3 1 g

CDLM-3813 D-Glucose HO*CD2(*CDOH)4*CDO 1 g50-99-7fl (U-13C6, 99% ; 1,2,3,4,5,6,6-D7, 97-98%) CLM-3721 DL-Glutamic Acid (1-13C, 99%) HOOC(CH2)2CH(NH2)*COOH 1 g617-65-2fl

CLM-674 L-Glutamic Acid (1-13C, 99%) HOOC(CH2)2CH(NH2)*COOH 1 g56-86-0fl

CLM-2024 L-Glutamic Acid (1,2-13C2, 99%) HOOC(CH2)2*CH(NH2)*COOH 0.25 g56-86-0fl

CLM-1800 L-Glutamic Acid (U-13C5, 98%) HOO*C(*CH2)2*CH(NH2)*COOH 0.25 g56-86-0fl 0.5 g 1 g

DLM-3725 L-Glutamic Acid (2,4,4-D3, 98%) HOOCCD2CH2CD(NH2)COOH 0.5 g56-86-0fl

DLM-556 L-Glutamic Acid (2,3,3,4,4-D5, 98%) HOOC(CD2)2CD(NH2)COOH 0.05 g2784-50-1 0.1 g

NLM-135 L-Glutamic Acid (15N, 98%) HOOC(CH2)2CH(*NH2)COOH 0.5 g21160-87-2 1 g

CNLM-554 L-Glutamic Acid (U-13C5, 98% ; 15N, 98%) HOO*C(*CH2)2*CH(*NH2)*COOH 0.25 g56-86-0fl 0.5 g 1 g

CLM-1822 L-Glutamine (U-13C5, 98%) H2N*CO(*CH2)2*CH(NH2)*COOH 0.1 g56-85-9fl 0.25 g 0.5 g DLM-1826 L-Glutamine (2,3,3,4,4-D5, 97%) H2NCO(CD2)2CD(NH2)COOH 0.1 g14341-78-7





28


NLM-1016 L-Glutamine (α-15N, 98%) H2NCO(CH2)2CH(*NH2)COOH 0.1 g80143-57-3 1 g

NLM-1328 L-Glutamine (15N2, 98%) H2*NCO(CH2)2CH(*NH2)COOH 0.25 g56-85-9fl

CNLM-1275 L-Glutamine (U-13C5, 98% ; U-15N2, 98%) H2*N*CO(*CH2)2*CH(*NH2)*COOH 0.1 g636-65-7 0.25 g 0.5 g

CNLM-4356 L-Glutamine-N-FMOC H2*N*CO(*CH2)2*CH(*NH-FMOC)*COOH 71989-20-3fl (U-13C5, 98% ; U-15N2, 98%) on request

CLM-1397 Glycerol (2-13C, 99%) (HOCH2)2*CHOH 0.25 g82425-96-5 0.5 g 1 g

CLM-1857 Glycerol (1,3-13C2, 99%) (HO*CH2)2CHOH 0.25 g56-81-5fl 0.5 g 1 g

CLM-1510 Glycerol (13C3, 99%) (HO*CH2)2*CHOH 1 g56-81-5fl 5 g DLM-1326 Glycerol [(OD)3, 98%] (DOCH2)2CHOD 5 g7325-16-8 10 g DLM-1229 Glycerol (1,1,2,3,3-D5, 99%) (HOCD2)2CDOH 1 g62502-71-0 5 g DLM-558 Glycerol (D8, 98%) (DOCD2)2CDOD 1 g7325-17-9 5 g

GLyCeRyL TRiPALmiTATe — See TRiPALmiTiN

CLM-422 Glycine (1-13C, 99%) H2NCH2*COOH 1 g20110-59-2 5 g

CLM-2152 Glycine-N-t-BOC (1-13C, 99%) CH2(NH-t-BOC)*COOH 1 g4530-20-5fl

CLM-3639 Glycine-N-FMOC (1-13C, 99%) CH2(NH-FMOC)*COOH 1 g29022-11-5fl

CLM-136 Glycine (2-13C, 99%) H2N*CH2COOH 0.5 g20220-62-6 1 g 5 g

CLM-1900 Glycine-N-t-BOC (2-13C, 99%) *CH2(NH-t-BOC)COOH 1 g4530-20-5fl CLM-2387 Glycine-N-FMOC (2-13C, 99%) *CH2(NH-FMOC)COOH 1 g29022-11-5fl 29

CLM-1017 Glycine (13C2, 99%) H2N*CH2*COOH 0.5 g67836-01-5 1 g 5 g

DLM-1674 Glycine (2,2-D2, 98%) H2NCD2COOH 5 g4896-75-7

DLM-2153 Glycine-N-t-BOC (2,2-D2, 98%) CD2(NH-t-BOC)COOH 1 g4530-20-5fl DLM-280-80 Glycine (D5, 80%) D2NCD2COOD 5 g4896-77-9

NLM-202 Glycine (15N, 98%) H2*NCH2COOH 1 g56-40-6fl 5 g

NLM-2109 Glycine-N-t-BOC (15N, 98%) CH2(*NH-t-BOC)COOH 1 g4530-20-5fl

NLM-694 Glycine-N-FMOC (15N, 98%) CH2(*NH-FMOC)COOH 1 g29022-11-5fl

CNLM-507 Glycine (1-13C, 99% ; 15N, 98%) H2*NCH2*COOH 1 g112898-03-0

CNLM-508 Glycine (2-13C, 99% ; 15N, 98%) H2*N*CH2COOH 0.5 g91795-59-4 1 g

CNLM-1673 Glycine (U-13C2, 98% ; 15N, 98%) H2*N*CH2*COOH 0.25 g56-40-6fl 0.5 g 1 g

CNLM-2412 Glycine-N-t-BOC (U-13C2, 98% ; 15N, 98%) *CH2(*NH-t-BOC)*COOH 0.1 g4530-20-5

CNLM-4357 Glycine-N-FMOC *CH2(*NH-FMOC)*COOH 0.1 g29022-11-5fl (U-13C2, 98% ; 15N, 98%) 0.25 g

H HePeS — See N-(2-HyDROXyeTHyL)PiPeRAZiNe-N’-2-eTHANeSuLFONiC ACiD

DLM-1342 n-Heptadecane (D36, 98%) CD3(CD2)15CD3 5 g39756-35-9

DLM-2731 Heptanoic Acid (D13, 98%) CD3(CD2)5COOH 0.5 g 111-14-8fl

CLM-351 Hexachlorobenzene (13C6, 99%) C6CI6 0.01 g 118-74-1fl

DLM-203 n-Hexadecane (D34, 98%) CD3(CD2)14CD3 0.1 g544-76-3fl 5 g





R E S E A R C H C O M P O U N D SR E S E A R C H C O M P O U N D S

30 31

DLM-3519 Hexanoic Acid (1-13C, 99%) CH3(CH2)4*COOH 0.5 g58454-07-2 (Caproic Acid)

HeXADeCANOiC ACiD — See PALmiTiC ACiD

DLM-612 Hexanoic Acid (methyl-D3, 98%) CD3(CH2)4COOH 0.1 g142-62-1fl 0.5 g 1 g CLM-1512 L-Histidine•HCl•H2O (ring-2-13C, 99%) 0.1 g7048-02-4fl (may contain < 5% D-isomer)

CLM-2264 L-Histidine•HCl•H2O (U-13C6, 98%) 0.05 g7048-02-4fl (may contain < 5% D-isomer) 0.1 g 0.25 g

HN N

COOH

NH2

HClH2O

.

.

NLM-2245 L-Histidine•HCl•H2O (α-15N, 98%) 0.25 g7048-02-4fl (may contain < 5% D-isomer)

NLM-846 L-Histidine•HCI•H2O (ring-pi-15N, 98%) 0.25 g7048-02-4fl (may contain < 5% D-isomer) NLM-1513 L-Histidine•HCl•H2O (U-15N3, 98%) on request7048-02-4fl

CNLM-758 L-Histidine•HCl•H2O on request7048-02-4fl (U-13C6, 98% ; U-15N3, 98%) (may contain < 5% D-isomer)

DLM-2741 Hydrazine (D4, 98%) D2NND2 5 g13762-95-3 (95% in D2O) (of soln.)

DLM-2306 Hydroquinone (D6, 98%) DOC6D4OD 1 g123-31-9fl 5 g

CLM-1321 4-Hydroxybenzaldehyde (ring-13C6, 99%) 0.1 g123-08-0fl

D-3-HyDROXyBuTyRiC ACiD, SODium SALT — See SODium D-3-HyDROXyBuTyRATe

DLM-3786 N-(2-Hydroxyethyl)piperazine-N’-2-ethanesulfonic Acid 0.25 g7356-45-9fl (D18, 98%) (HEPES)

NLM-426 Hydroxylamine•HCl (15N, 98%) H2*NOH•HCl 0.5 g5470-11-1fl 1 g 4-HyDROXyPHeNyLALANiNe — See TyROSiNe

IDLM-3033 Imidazole (D4, 98%) 1 g6923-01-9 5 g CLM-1863 Indole (2-13C, 98%) 0.25 g120-72-9fl 0.5 g CLM-794 Indole (4-13C, 95-99%) *CC7H7N 0.25 g120-72-9fl 0.5 g CLM-1896 Indole-3-acetic Acid (phenyl-13C6, 99%) 0.01 g87-51-4fl

CLM-1025 Iodoethane (1-13C, 99%) CH3*CH2I 0.5 g75560-39-3 (Ethyl Iodide) 1 g Stabilized with copper wire.

CLM-741 Iodoethane (13C2, 99%) *CH3*CH2I 0.25 g34189-74-7 Stabilized with copper wire. 0.5 g

DLM-1023 Iodoethane (1,1-D2, 98%) CH3CD2I 5 g75-03-6fl Stabilized with copper wire. FLAmmABLe LiquiD

DLM-1024 Iodoethane (2,2,2-D3, 98%) CD3CH2I 5 g7439-87-4 Stabilized with copper wire.

iODOmeTHANe — See meTHyL iODiDe

CLM-1026 L-Isoleucine (1-13C, 99%) CH3CH2CH(CH3)CH(NH2)*COOH 0.5 g73-32-5fl 1 g

CLM-2248 L-Isoleucine (U-13C6, 98%) *CH3*CH2*CH(*CH3)*CH(NH2)*COOH 0.05 g73-32-5fl 0.1 g 0.25 g

NLM-292 L-Isoleucine (15N, 98%) CH3CH2CH(CH3)CH(*NH2)COOH 0.25 g59935-30-7

NLM-2167 L-Isoleucine-N-t-BOC (15N, 98%) CH3CH2CH(CH3)CH(*NH-t-BOC)COOH 0.25 g13139-16-7fl

NLM-391 L-Isoleucine-N-FMOC (15N, 98%) CH3CH2CH(CH3)CH(*NH-FMOC)COOH 0.25 g71989-23-6fl

CNLM-561 L-Isoleucine (U-13C6, 98% ; 15N, 98%) *CH3*CH2*CH(*CH3)*CH(*NH2)*COOH 73-32-5fl on request

CNLM-4346 L-Isoleucine-N-FMOC (U-13C6, 98% ; 15N, 98%) *CH3*CH2*CH(*CH3)*CH(*NH-FMOC)*COOH 71989-23-6fl on request

DLM-1134 Isopropanol (2-D, 98%) (CH3)2CDOH 5 g67-63-0fl FLAmmABLe LiquiD




HN N

COOH

NH2

HClH2O

.

.

2

α

HN N

COOH

NH2

HClH2O

.

.*

α

HN N

COOH

NH2

HClH2O

.

.*

HN N

COOH

NH2

HClH2O

.

.* * *

N

N

CD2CD2SO3D

CD2CD2OD

O

OH

HN N

COOH

NH2

HClH2O

.

.

NH

2

34

N

DN

NH

O

OH

32 33

K CLM-6820 α-Ketobutyric Acid, Sodium Salt *CH3CH2COCOONa on request (methyl-13C, 99%)

CLM-6164 α-Ketobutyric Acid, Sodium Salt (U-13C4, 98%) *CH3*CH2*CO*COONa 0.5 g

CDLM-4611 α-Ketobutyric Acid, Sodium Salt *CH3*CD2*CO*COONa 0.1 g2013-26-5fl (13C4, 99% ; 3,3-D2, 98%) 0.25 g

CLM-2093 α-Ketoisocaproic Acid, Sodium Salt (CH3)2CHCH2CO*COONa 1 g4502-00-5fl (1-13C, 99%) 10 g (Sodium 2-Keto-4-methylpentanoate)

DLM-1944 α-Ketoisocaproic Acid, Sodium Salt CD3CH(CH3)CH2COCOONa 0.5 g4502-00-5fl (methyl-D3, 98%)

DLM-4214 α-Ketoisocaproic Acid, Sodium Salt (CD3)CDCH2COCOONa 0.1 g4502-00-5fl (isopropyl-D7, 98%) 0.25 g

CLM-6821 α-Ketoisovaleric Acid, Sodium Salt (*CH3)2CHCOCOONa on request3715-29-5fl (dimethyl-13C2, 99%)

CLM-4418 α-Ketoisovaleric Acid, Sodium Salt (*CH3)2*CH*CO*COONa 0.25 g3715-29-5fl (U-13C5, 98%)

CDLM-4418 α-Ketoisovaleric Acid, Sodium Salt (*CH3)2*CD*CO*COONa 0.25 g3715-29-5fl (U-13C5, 98% ; 3-D1, 98%)

LNSK-A Labeled Amino Acid Standards — Set A 1 vial Stable isotope Reference Standards for mass Spectrometry. 10 vials Set A contains lableled versions of the following: Glycine, L-Alanine, L-valine, L-Leucine, L-methionine, L-Phenylalanine, L-Tyrosine, L-Aspartic Acid, L-Glutamic Acid, L-Ornithine, L-Citrulline and L-Arginine.

NSK-B Labeled Carnitine Standards — Set B 1 vial Stable isotope Reference Standards for mass Spectrometry. 10 vials Set B contains lableled versions of the following: L-Carnitine, L-Acetylcarnitine, L-Propionylcarnitine, L-Butyrylcarnitine, L-isovalerylcarnitine, L-Octanoylcarnitine, L-myristoylcarnitine, L-Palmitoylcarnitine.

NSK-AB Labeled Standards — Sets A and B 2 x 10 vials

LAD — See LiTHium ALumiNum DeuTeRiDe

L-LACTiC ACiD, SODium SALT — See SODium L-LACTATe

CLM-1586 Lauric Acid (1-13C, 99%) CH3(CH2)10*COOH 1 g93639-08-8 (Dodecanoic Acid) 5 g

DLM-3062 Lauric Acid (methyl-D3, 99%) CD3(CH2)10COOH 0.5 g143-07-7fl 1 g

DLM-563 Lauric Acid (D23, 98%) CD3(CD2)10COOH 1 g143-07-7fl

CLM-468 L-Leucine (1-13C, 99%) (CH3)2CHCH2CH(NH2)*COOH 1 g74292-94-7 5 g

CLM-2155 L-Leucine-N-t-BOC•H2O (1-13C, 99%) (CH3)2CHCH2CH(NH-t-BOC)*COOH•H2O 1 g13139-15-6fl

CLM-3691 L-Leucine-N-FMOC (1-13C, 99%) (CH3)2CHCH2CH(NH-FMOC)*COOH 1 g35661-60-0

CLM-2014 L-Leucine (2-13C, 99%) (CH3)2CHCH2*CH(NH2)COOH 0.5 g61-90-5fl 1 g

CLM-2010 L-Leucine-N-t-BOC•H2O (2-13C, 99%) (CH3)2CHCH2*CH(NH-t-BOC)COOH•H2O 0.25 g13139-15-6fl

CLM-3524 L-Leucine (1,2-13C2, 99%) (CH3)2CH*CH(NH2)*COOH 0.25 g61-90-5fl

CLM-2262 L-Leucine (U-13C6, 98%) (*CH3)2*CH*CH2*CH(NH2)*COOH 0.05 g61-90-5fl 0.1 g 0.25 g

DLM-1259 L-Leucine (5,5,5-D3, 98%) CD3CH(CH3)CH2CH(NH2)COOH 1 g87828-86-2 5 g DLM-2736 L-Leucine-N-t-BOC•H2O (5,5,5-D3, 98%) CD3CH(CH3)CH2CH(NH-t-BOC)COOH•H2O 1 g13139-15-6fl

DLM-4212 L-Leucine (isopropyl-D7, 98%) (CD3)2CDCH2CH(NH2)COOH 1 g61-90-5fl

DLM-567 L-Leucine (D10, 98%) (CD3)2CDCD2CD(NH2)COOH 0.25 g106972-44-5

NLM-142 L-Leucine (15N, 98%) (CH3)2CHCH2CH(*NH2)COOH 0.5 g59935-31-8 1 g

NLM-1904 L-Leucine-N-t-BOC•H2O (15N, 98%) (CH3)2CHCH2CH(*NH-t-BOC)COOH•H2O 1 g13139-15-6fl

NLM-2397 L-Leucine-N-FMOC (15N, 98%) (CH3)2CHCH2CH(*NH-FMOC)COOH 1 g35661-60-0fl

CNLM-615 L-Leucine (1-13C, 99% ; 15N, 98%) (CH3)2CHCH2CH(*NH2)*COOH 1 g61-90-5fl

CNLM-281 L-Leucine (U-13C6, 98% ; 15N, 98%) (*CH3)2*CH*CH2*CH(*NH2)*COOH 0.05 g61-90-5fl 0.1 g 0.25 g





34 35

CNLM-2396 L-Leucine-N-t-BOC•H2O (*CH3)2*CH*CH2*CH(*NH-t-BOC)*COOH•H2O 0.05 g13139-15-6fl (U-13C6, 98% ; 15N, 98%)

CNLM-4345 L-Leucine-N-FMOC (U-13C6, 98%; 15N, 98%) (*CH3)2*CH*CH2*CH(*NH-FMOC)*COOH 0.1 g35661-60-0fl 0.25 g

DNLM-4642 L-Leucine (D10, 98% ; 15N, 97%) (CD3)2CDCD2CD(*NH2)COOH 0.5 g61-90-5fl

CLM-3960 Linoleic Acid, Ethyl Ester *CH3(*CH2)4*CH=*CH*CH2*CH=*CH(*CH2)7*COOC2H5 544-35-4fl (linoleic-U-13C18, 98%) Special shipping requirements may apply. 0.5 g Please inquire at time of order. DLM-1909 Linoleic Acid, Ethyl Ester CH3(CH2)4CD=CDCH2CD=CD(CH2)7COOC2H5

544-35-4fl (9,10,12,13-D4, 95%) Special shipping requirements may apply. on request Please inquire at time of order.

DLM-766 Linoleic Acid, Ethyl Ester (D31, 98%) CD3(CD2)4CD=CDCD2CD=CD(CD2)7COOC2H5 544-35-4fl Special shipping requirements may apply. Please inquire at time of order. on request

CLM-493 Linolenic Acid, Ethyl Ester (18-13C, 99%) *CH3CH2CH=CH(CH2CH=CH)2(CH2)7COOC2H5 1191-41-9fl Special shipping requirements may apply. Please inquire at time of order. on request

DLM-2351 Linolenic Acid, Ethyl Ester CD3CD2CH=CH(CH2CH=CH)2(CH2)7COOC2H5 0.25 g544-35-4fl (17,17,18,18,18-D5, 98%) Special shipping requirements may apply. Please inquire at time of order.

LIPIDS : Please inquire about Lipids or Fatty Acids not listed in this catalog.

DLM-356 Lithium Aluminum Deuteride (D4, 98%) LiAlD4 1 g14128-54-2 (LAD) 5 g DANGeROuS WHeN WeT ReACTS viOLeNTLy WiTH WATeR Cargo Air Only.

CLM-653 L-Lysine•2HCl (1-13C, 99%) H2N(CH2)4CH(NH2)*COOH•2HCl 0.25 g657-26-1fl 0.5 g

CLM-6194 L-Lysine-α-N-FMOC, ε-N-t-BOC (1-13C, 99%) HN-t-BOC(CH2)4CH(NH-FMOC)*COOH 0.1 g71989-26-9fl

CLM-632 L-Lysine•2HCl (6-13C, 99%) H2N*CH2(CH2)3CH(NH2)COOH•2HCl 0.25 g657-26-1fl

CLM-2247 L-Lysine•2HCl (U-13C6, 98%) H2N(*CH2)4*CH(NH2)*COOH•2HCl 0.05 g657-26-1fl 0.1 g 0.25 g

DLM-2640 L-Lysine•2HCl (4,4,5,5-D4, 96-98%) H2NCH2(CD2)2CH2CH(NH2)COOH•2HCl 0.5 g657-26-1fl

NLM-143 L-Lysine•2HCl (α-15N, 95-99%) H2N(CH2)4CH(*NH2)COOH•2HCl 0.25 g657-26-1fl 1 g

NLM-631 L-Lysine•2HCl (ε-15N, 98%) H2*N(CH2)4CH(NH2)COOH•2HCI 0.5 g657-26-1fl

NLM-1554 L-Lysine•2HCl (15N2, 98%) H2*N(CH2)4CH(*NH2)COOH•2HCI 0.1 g657-26-1fl

CNLM-291 L-Lysine•2HCl (U-13C6, 98% ; 15N2, 98%) H2*N(*CH2)4*CH(*NH2)*COOH•2HCl 0.05 g657-26-1fl 0.1 g 0.25 g

MDLM-1129 Maleic Acid (2,3-D2, 98%) 5 g24461-33-4

CLM-310 Maleic Anhydride (1,4-13C2, 99%) 0.25 g108-31-6fl CLM-312 Maleic Anhydride (2,3-13C2, 99%) 0.1 g41403-35-4

OO O

2 3

CLM-751 Malonic Acid (2-13C, 99%) *CH2(COOH)2 0.5 g55514-11-9 1 g

CLM-1248 Malonic Acid (1,3-13C2, 99%) CH2(*COOH)2 0.25 g141-82-2fl 0.5 g 1 g

CLM-6123 Malonic Acid (13C3, 99%) *CH2(*COOH)2 0.25 g141-82-2fl

DLM-205 Malonic Acid (D4, 98%) CD2(COOD)2 50 g813-56-9

CLM-1189 D-Mannitol (1-13C, 99%) HOCH2(CHOH)4*CH2OH 0.25 g132202-29-0 0.5 g 1 g

CLM-358 D-Mannose (1-13C, 99%) HOCH2(CHOH)4*CHO 0.25 g70849-31-9 0.5 g 1 g

DLM-2713 2-Mercaptoethanol (D6, 98%) DS(CD2)2OD 0.5 g60-24-2fl TOXiC

meS — See 2-(N-mORPHOLiNO)eTHANeSuLFONiC ACiD CLM-1280 Methacetin (methoxy-13C, 99%) CH3CONHC6H4O*CH3 1 g72156-70-8 (p-Acetanisidine or N-[4-Methoxyphenyl]acetamide) 10 g





OO O

1 4

COOHHOOC

36 37

DLM-1981 Methanesulfonic Acid (D4, 97-98%) CD3SO3D 5 g75-75-2fl

CLM-359 Methanol (13C, 99%) *CH3OH 1 g14742-26-8 (Methyl Alcohol) 5 g

DLM-1211 Methanol (D1, 98%) CH2DOH 5 g4206-31-9

CLM-206 L-Methionine (methyl-13C, 98%) *CH3SCH2CH2CH(NH2)COOH 1 g49705-26-2

CLM-893 L-Methionine (U-13C5, 98%) *CH3S*CH2*CH2*CH(NH2)*COOH 0.05 g63-68-3fl (may contain < 5% D-isomer) 0.1 g 0.25 g DLM-431 L-Methionine (methyl-D3, 98%) CD3SCH2CH2CH(NH2)COOH 1 g13010-53-2 5 g

NLM-752 L-Methionine (15N, 98%) CH3SCH2CH2CH(*NH2)COOH 0.5 g63-68-3fl 1 g

CNLM-759 L-Methionine (U-13C5, 98% ; 15N, 98%) *CH3S*CHc*CH2*CH(*NH2)*COOH 0.05 g63-68-3fl 0.1 g 0.25 g

CNLM-4358 L-Methionine-N-FMOC *CH3S*CH2*CH2*CH(*NH-FMOC)*COOH 0.1 g71989-28-1fl (U-13C5, 98% ; 15N, 98%)

CLM-1212 Methyl Acetoacetate (1,2,3,4-13C4, 99%) *CH3*CO*CH2*COOCH3 0.5 g105-45-3fl

DLM-178 Methyl Acrylate (2,3,3-D3, 98%) D2C=CDCOOCH3 0.5 g96-33-3fl inhibited with 0.1% BHT.

CLM-360 Methylamine•HCl (13C, 99%) *CH3NH2•HCl 1 g60656-93-1

NLM-361 Methylamine•HCl (15N, 98%) CH3*NH2•HCl 0.5 g3852-22-0 1 g

DLM-289 Methylamine•HCl (methyl-D3, 98%) CD3NH2•HCI 1 g593-51-1fl

CLM-1593 Methylene Chloride (13C, 99%) *CH2Cl2 0.25 g70110-03-1 (Dichloromethane) 0.5 g

DLM-651 Methyl Formate (formyl-D, 99%) DCOOCH3 5 g23731-38-6 10 g

CLM-287 Methyl Iodide (13C, 99%) *CH3I 1 g4227-95-6 (Iodomethane) 5 g Stabilized with copper wire. 10 g TOXiC Air freight forbidden.

DLM-471 Methyl Methacrylate (D8, 98%) CD2=C(CD3)COOCD3 1 g35233-69-3 inhibited with 0.1% BHT. 5 g

DLM-4363 2-(N-morpholino)ethanesulfonic Acid (D13, 98%) 0.5 g4432-31-9fl (MES)

O

N

CD2CD2SO3D

CLM-1844 Myristic Acid (1-13C, 99%) CH3(CH2)12*COOH 1 g57677-52-8 (Tetradecanoic Acid)

CLM-3665 Myristic Acid (1,2,3-13C3, 99%) CH3(CH2)10(*CH2)2*COOH 0.5 g544-63-8fl

DLM-208 Myristic Acid (D27, 98%) CD3(CD2)12COOH 1 g60658-41-5

NDLM-365 Naphthalene (D8, 99%) 1 g1146-65-2 FLAmmABLe SOLiD 5 g 10 g NLM-297 Nitric Acid (15N, 98%) H*NO3 1 g43625-06-5 (40% w/w solution in H2O) (contained acid)

CLM-675 Nitrobenzene (13C6, 99%) *C6H5NO2 0.1 g78813-15-6 TOXiC 0.25 g 0.5 g

NLM-1042 Nitrobenzene (15N, 98%) C6H5*NO2 1 g3681-79-6 TOXiC

DLM-1346 n-Nonadecane (D40, 98%) CD3(CD2)17CD3 0.1 g39756-30-0 1 g

DLM-2438 n-Nonane (D20, 98%) CD3(CD2)7CD3 1 g111-84-2fl FLAmmABLe LiquiD 5 g

O OCTADeCANOiC ACiD — See STeARiC ACiD

DLM-795 n-Octadecanol (D37, 98%) CD3(CD2)17OH 1 g112-92-5fl

9-OCTADeCeNOiC ACiD — See OLeiC ACiD

CLM-293 Octanoic Acid (1-13C, 99%) CH3(CH2)6*COOH 1 g59669-16-8 CORROSive 5 g

CLM-3827 Octanoic Acid (1,2-13C2, 99%) CH3(CH2)5*CH2*COOH 1 g124-07-2fl CORROSive





38 39

CLM-2721 Octanoic Acid (1,2,3,4-13C4, 99%) CH3(CH2)3(*CH2)3*COOH 0.5 g124-07-2fl CORROSive 1 g

DLM-619 Octanoic Acid (D15, 98%) CD3(CD2)6COOH 1 g69974-55-6 CORROSive

OCTANOiC ACiD, SODium SALT — See SODium OCTANOATe

DLM-6726 n-Octyl β-Glucoside (D24, 98%) 0.1 g29836-26-8fl (n-Octyl Glucoside)

CLM-149 Oleic Acid (1-13C, 99%) CH3(CH2)7CH=CH(CH2)7*COOH 0.5 g82005-44-5 (9-Octadecenoic Acid) 1 g

DLM-2968 L-Oleic Acid (11,11-D2, 98%) CH3(CH2)6CD2CH=CH(CH2)7COOH 0.1 g112-80-1fl

DLM-2969 L-Ornithine•HCl (3,3,4,4,5,5-D6, 98%) H2N(CD2)3CH(NH2)COOH•HCI 0.1 g3184-13-2fl 0.25 g

DLM-4261 L-Ornithine•2HCl (5,5-D2, 98%) H2NCD2(CH2)2CH(NH2)COOH•2HCI 0.25 g6211-16-1fl

NLM-3610 L-Ornithine•HCl (15N2, 98%) H2*N(CH2)3CH(*NH2)COOH•HCI 0.25 g3184-13-2fl

PCLM-150 Palmitic Acid (1-13C, 99%) CH3(CH2)14*COOH 1 g57677-53-9 (Hexadecanoic Acid) 5 g 10 g

CLM-2120 Palmitic Acid (2-13C, 99%) CH3(CH2)13*CH2COOH 1 g57-10-3fl

CLM-409 Palmitic Acid (U-13C16, 98%) *CH3(*CH2)14*COOH 0.5 g57-10-3fl

DLM-1153 Palmitic Acid (2,2-D2, 98%) CH3(CH2)13CD2COOH 1 g62689-96-7

DLM-2890 Palmitic Acid (9,9-D2, 98%) CH3(CH2)6CD2(CH2)7COOH 1 g 57-10-3fl

DLM-2891 Palmitic Acid (13,13-D2, 98%) CH3(CH2)2CD2(CH2)11COOH 0.5 g57-10-3fl

DLM-611 Palmitic Acid (methyl-D3, 98%) CD3(CH2)14COOH 0.5 g57-10-3fl

DLM-2893 Palmitic Acid (7,7,8,8-D4, 98%) CH3(CH2)7(CD2)2(CH2)5COOH 0.1 g57-10-3fl 0.5 g

DLM-2895 Palmitic Acid (9,9,…16,16,16-D17, 98%) CD3(CD2)7(CH2)7COOH 0.1 g57-10-3fl

DLM-215 Palmitic Acid (D31, 98%) CD3(CD2)14COOH 1 g39756-30-4 PALmiTiC ACiD, SODium SALT — See SODium PALmiTATe

CLM-229 Paraformaldehyde (13C, 99%) (*CH2O)n 1 g30525-89-4fl (See also formaldehyde)

DLM-300 Paraformaldehyde (D2, 99%) (CD2O)n 5 g32008-59-6 (See also formaldehyde)

DLM-1283 n-Pentadecane (D32, 98%) CD3(CD2)13CD3 1 g36340-20-2 5 g

DLM-790 n-Pentanol (D11, 98%) CD3(CD2)4OH 1 g71-41-0fl

CLM-1051 Phenol (1-13C, 99%) 0.25 g108-95-2fl TOXiC

OH

12

3

4

5

6

CLM-216 Phenol (13C6, 99%) *C6H5OH 0.1 g89059-34-7 TOXiC

DLM-695 Phenol (ring-D5, 98%) C6D5OH 1 g4165-62-2 TOXiC 5 g

DLM-370 Phenol (D6, 98%) C6D5OD 5 g13127-88-3 TOXiC CLM-2170 L-Phenylalanine-N-t-BOC (1-13C, 99%) C6H5CH2CH(NH-t-BOC)*COOH 0.5 g13734-34-4fl

CLM-4824 L-Phenylalanine-N-FMOC (1-13C, 99%) C6H5CH2CH(NH-FMOC)*COOH 0.5 g35661-40-6fl CLM-1631 L-Phenylalanine (2-13C, 99%) C6H5CH2*CH(NH2)COOH 0.05 g63-91-2fl 0.25 g

CLM-2009 L-Phenylalanine-N-t-BOC (2-13C, 99%) C6H5CH2*CH(NH-t-BOC)COOH 0.25 g13734-34-4fl CLM-1053 L-Phenylalanine (3-13C, 99%) C6H5*CH2CH(NH2)COOH 0.1 g63-91-2fl 0.25 g

CLM-1055 L-Phenylalanine (ring-13C6, 99%) *C6H5CH2CH(NH2)COOH 0.25 g63-91-2fl

CLM-2061 L-Phenylalanine-N-t-BOC (ring-13C6, 99%) *C6H5CH2CH(NH-t-BOC)COOH 0.1 g13734-34-4fl

CLM-3684 L-Phenylalanine-N-FMOC (ring-13C6, 99%) *C6H5CH2CH(NH-FMOC)COOH 0.1 g35661-40-6fl





OHHO

HO

O

OC8D17

HOD2C

40 41

CLM-2250 L-Phenylalanine (U-13C9, 98%) *C6H5*CH2*CH(NH2)*COOH 0.25 g63-91-2fl 0.5 g 1 g

DLM-1258 L-Phenylalanine (ring-D5, 98%) C6D5CH2CH(NH2)COOH 1 g56253-90-8 5 g

DLM-2157 L-Phenylalanine-N-t-BOC (ring-D5, 98%) C6D5CH2CH(NH-t-BOC)COOH 1 g13734-34-4fl

DLM-372 L-Phe ny la la nine (D8, 98%) C6D5CD2CD(NH2)COOH 1 g63-91-2fl

NLM-108 L-Phenylalanine (15N, 98%) C6H5CH2CH(*NH2)COOH 0.5 g29700-34-3 1 g

NLM-1905 L-Phenylalanine-N-t-BOC (15N, 98%) C6H5CH2CH(*NH-t-BOC)COOH 1 g13734-34-4fl NLM-1265 L-Phenylalanine-N-FMOC (15N, 98%) C6H5CH2CH(*NH-FMOC)COOH 1 g35661-40-6fl

CNLM-575 L-Phenylalanine (U-13C9, 98% ; 15N, 98%) *C6H5*CH2*CH(*NH2)*COOH 0.25 g63-91-2fl 0.5 g 1 g

CNLM-4362 L-Phenylalanine-N-FMOC *C6H5*CH2*CH(*NH-FMOC)*COOH 0.1 g 35661-40-6fl (U-13C9, 98% ; 15N, 98%) 0.25 g

DLM-4341 DL-α-Phosphatidylcholine, Dihexanoyl 0.1 g34506-67-7fl (D40, 98%) (DHPC)

DLM-605 L-α-Phosphatidylcholine, Dimyristoyl 0.1 g18194-24-6fl (dimyristoyl-D54, 98%) (DMPC)

DLM-298 Phosphorylcholine Chloride (trimethyl-D9, 98%) ClN(CD3)3CH2CH2OPO3Ca•H2O 0.5 g4826-71-5fl (Calcium salt monohydrate) DLM-4781 [Piperazine-N,N’-bis(2-ethanesulfonic acid)] (D18, 98%) 0.25 g5625-37-6fl (PIPES)

NN

DO3S

SO3D

CLM-297 Potassium Cyanide (13C, 99%) K*CN 1 g25909-68-6 TOXiC 5 g 10 g

NLM-111 Potassium Cyanide (15N, 98%) KC*N 0.5 g5297-01-8 TOXiC 1 g

NLM-765 Potassium Nitrate (15N, 98%) K*NO3 1 g57654-83-8

CLM-1889 Potassium Palmitate (1-13C, 99%) CH3(CH2)14*COOK 1 g2624-31-9fl

CLM-3943 Potassium Palmitate (U-13C16, 98%) *CH3(*CH2)14*COOK 0.5 g2624-31-9fl

DLM-3773 Potassium Palmitate (2,2-D2, 97%) CH3(CH2)13CD2COOK 1 g2624-31-9fl

NLM-367 Potassium Phthalimide (15N, 98%) 5 g53510-88-6 10 g

N

O

O

- K+*

CLM-457 Progesterone (3,4-13C2, 90%) on request 57-83-0fl

O

O

3

4

CLM-510 L-Proline (1-13C, 99%) 0.25 g147-85-3fl

HN

COOH*

CLM-2260 L-Proline (U-13C5, 98%) HN(*CH2)3*CH*COOH 0.1 g147-85-3fl 0.25 g 0.5 g

DLM-487 L-Proline (D7, 97-98%) HN(CD2)3CDCOOH 0.1 g147-85-3fl 0.25 g

NLM-835 L-Proline (15N, 98%) H*N(CH2)3CHCOOH 0.25 g147-85-3fl 0.5 g

NLM-2329 L-Proline-N-t-BOC (15N, 98%) (*N-t-BOC)(CH2)3CHCOOH 0.25 g15761-39-4fl

NLM-3906 L-Proline-N-FMOC (15N, 98%) (*N-FMOC)(CH2)3CHCOOH 0.25 g71989-31-6fl

CNLM-436 L-Proline (U-13C5, 98% ; 15N, 98%) H*N(*CH2)3*CH*COOH 0.1 g147-85-3fl 0.25 g 0.5 g

CNLM-4347 L-Proline-N-FMOC (U-13C5, 98% ; 15N, 98%) (*N-FMOC)(*CH2)3*CH*COOH 0.1 g71989-31-6fl 0.25 g

DLM-154 1,2-Propanediol (D6, 98%) CD3CD(OH)CD2OH 5 g57-55-6fl

DLM-767 n-Propanol (OD, 99%) CH3(CH2)2OD 25 g71-23-8fl FLAmmABLe LiquiD





HC

H2C

H2C

O

O

O

C

C

P

O

O

O

O

O

N +

-

(CD2)12CD3

(CD2)12CD3

DC

D2C

D2C

O

O

O

C

C

P

O

O

O

O

-

(CD2)4CD3

(CD2)4CD3

ON +

42 43

CLM-646 Propionic Acid (1-13C, 99%) CH3CH2*COOH 1 g6212-69-7 CORROSive

DLM-1137 Propionic Acid (methyl-D3, 98%) CD3CH2COOH 5 g55577-88-3 CORROSive

DLM-2488 Propionic Acid (2,2-D2, 98%) CH3CD2COOH 1 g19136-91-5 CORROSive 5 g

DLM-1919 Propionic Acid (D5, 98%) CD3CD2COOH 5 g79-09-4fl CORROSive

PROPiONiC ACiD, SODium SALT — See SODium PROPiONATe

NLM-305 Pyridine (15N, 98%) 0.5 g110-86-1fl PyRuviC ACiD, SODium SALT — See SODium PyRuvATe

R CLM-1069 D-Ribose (2-13C, 99%) *HOCH2(CHOH)2(*CHOH)CHO 0.25 g83379-40-2 0.5 g 1 g

CLM-1066 D-Ribose (5-13C, 99%) HO*CH2(CHOH)3CHO 0.25 g50-69-1fl 0.5 g 1 g

CLM-3652 D-Ribose (U-13C5, 98%) HO*CH2(*CHOH)3*CHO 0.1 g50-69-1fl

SCLM-1573 L-Serine (1-13C, 99%) HOCH2CH(NH2)*COOH 0.25 g81201-84-5 CLM-2013 L-Serine (2-13C, 99%) HOCH2*CH(NH2)COOH 0.1 g89232-76-8

CLM-1572 L-Serine (3-13C, 99%) HO*CH2CH(NH2)COOH 0.1 g89232-77-9 0.25 g

CLM-756 L-Serine-N-t-BOC, O-Benzyl Ether C6H5CH2O*CH2CH(NH-t-BOC)COOH on request23680-31-1fl (3-13C, 99%)

CLM-1574 L-Serine (U-13C3, 98%) HO*CH2*CH(NH2)*COOH 0.1 g201595-68-8 0.25 g 0.5 g

DLM-582 L-Serine (2,3,3-D3, 98%) HOCD2CD(NH2)COOH 0.1 g105591-10-4 0.5 g

NLM-2036 L-Serine (15N, 98%) HOCH2CH(*NH2)COOH 0.5 g59935-32-9 1 g

CNLM-474 L-Serine (U-13C3, 98% ; 15N, 98%) HO*CH2*CH(*NH2)*COOH 0.1 g56-45-1fl 0.25 g 0.5 g

CNLM-4755 L-Serine-N-FMOC, O-t-Butyl Ether (CH3)3CO*CH2*CH(*NH-FMOC)*COOH 0.1 g 71989-33-8fl (U-13C3, 98% ; 15N, 98%) (may contain 3% D-isomer)

CLM-156 Sodium Acetate (1-13C, 99%) CH3*COONa 1 g 23424-28-4 5 g 10 g

CLM-381 Sodium Acetate (2-13C, 99%) *CH3COONa 1 g13291-89-9 5 g 10 g

CLM-440 Sodium Acetate (13C2, 99%) *CH3*COONa 1 g563-74-56-2 5 g

DLM-3126 Sodium Acetate (D3, 99%) CD3COONa 25 g39230-37-0

CDLM-3457 Sodium Acetate (13C2, 99% ; D3, 98%) *CD3*COONa 1 g123333-80-2

CDLM-611 Sodium Acetate (1-13C, 99% ; D3, 98%) CD3*COONa 1 g127-09-3fl

CDLM-1240 Sodium Acetate (2-13C, 99% ; D3, 98%) *CD3COONa 1 g85355-10-8

CLM-441 Sodium Bicarbonate (13C, 99%) NaH*CO3 1 g87081-58-1 5 g

DLM-226 So di um Borodeuteride (D4, 99%) NaBD4 1 g15681-89-7 DANGeROuS WHeN WeT 5 g Air Cargo Only. 10 g

CLM-1256 Sodium Butyrate (1-13C, 99%) CH3CH2CH2*COONa 1 g62601-04-1 5 g

CLM-306 Sodium Carbonate (13C, 99%) Na2*CO3 1 g497-19-8fl 5 g

CLM-378 Sodium Cyanide (13C, 99%) Na*CN 1 g57991-39-6 TOXiC 5 g

NLM-3005 Sodium Cyanide (15N, 98%) NaC*N 0.5 g143-33-9fl TOXiC





N

44 45

DLM-197 Sodium Dodecyl Sulfate (D25, 98%) CD3(CD2)11OSO3Na 1 g151-21-3fl (Dodecyl Sodium Sulfate) CLM-583 Sodium Formate (13C, 99%) H*COONa 1 g23102-86-5 5 g

DLM-1361 Sodium Formate (D, 99%) DCOONa 5 g3996-15-4

CLM-3706 Sodium D-3-Hydroxybutyrate (2,4-13C2, 99%) *CH3CH(OH)*CH2COONa 1 g13613-65-5fl

CLM-1577 Sodium L-Lactate (1-13C, 99%) CH3CH(OH)*COONa 1 g of compound867-56-1fl (L-Lactic Acid, Sodium Salt) (20% w/w in H2O) CLM-1578 Sodium L-Lactate (3-13C, 98%) *CH3CH(OH)COONa 0.25 g of compound867-56-1fl (20% w/w in H2O) 0.5 g of compound 1 g of compound NLM-658 Sodium Nitrite (15N, 98%) Na*NO2 1 g68378-96-1 OXiDiZeR, TOXiC 5 g

CLM-1948 Sodium Octanoate (1-13C, 99%) CH3(CH2)6*COONa 1 g201612-61-5 10 x 0.1 g 5 g

CLM-174 Sodium Palmitate (1-13C, 99%) CH3(CH2)14*COONa 1 g408-35-5fl

CLM-771 Sodium Propionate (1-13C, 99%) CH3CH2*COONa 1 g62601-06-3

CLM-1506 Sodium Propionate (2-13C, 99%) CH3*CH2COONa 0.5 g137-40-6fl 1 g

CLM-1865 Sodium Propionate (13C3, 99%) *CH3*CH2*COONa 0.1 g137-40-6fl

CLM-1082 Sodium Pyruvate (1-13C, 99%) CH3CO*COONa 0.25 g87976-71-4 0.5 g 1 g CLM-1580 Sodium Pyruvate (2-13C, 99%) CH3*COCOONa 0.5 g87976-71-3 1 g

CLM-1575 Sodium Pyruvate (3-13C, 99%) *CH3COCOONa 0.25 g124052-04-6 0.5 g 1 g

CLM-3507 Sodium Pyruvate (2,3-13C2, 99%) *CH3*COCOONa 0.5 g89196-78-1 1 g

CLM-2440 Sodium Pyruvate (13C3, 99%) *CH3*CO*COONa 0.5 g142014-11-7 1 g

CLM-676 Stearic Acid (1-13C, 99%) CH3(CH2)16*COOH 1 g85541-42-0 (Octadecanoic Acid) 5 g

DLM-1154 Stearic Acid (methyl-D3, 98%) CD3(CH2)16COOH 0.1 g62163-39-7 0.25 g

DLM-379 Stearic Acid (D35, 98%) CD3(CD2)16COOH 1 g17660-51-4 STEROIDS: Please inquire about any Steroid not listed in this catalog.

DLM-380 Styrene (D8, 98%) C6D5CD=CD2 1 g19361-62-7 inhibited with BHT. 5 g FLAmmABLe LiquiD CLM-1084 Succinic Acid (1,4-13C2, 99%) HOO*C(CH2)2*COOH 0.25 g79864-95-2 0.5 g 1 g

CLM-1199 Succinic Acid (2,3-13C2, 99%) HOOC(*CH2)2COOH 1 g61128-08-3

CLM-1571 Succinic Acid (13C4, 99%) HOO*C(*CH2)2*COOH 0.1 g110-15-6fl 0.25 g DLM-584 Succinic Acid (D4, 98%) HOOC(CD2)2COOH 5 g14493-42-6 10 g

T TCEP—SEETRIS(2-CARBOXYETHYL)PHOSPHINE•DCL

DLM-1088 Terephthalic Acid (ring-D4, 98%) 1 g60088-54-2 5 g DLM-450 o-Terphenyl (D14, 98%) 1 g84-15-1fl 5 g

CLM-159 Testosterone (3,4-13C2, 90%) 0.01 g58-22-0fl DLM-683 Testosterone (1,2-D2, 98%) C19H26D2O2 0.1 g58-22-0fl

DLM-2209 n-Tetracosane (D50, 98%) CD3(CD2)22CD3 0.5 g16416-32-3

DLM-670 n-Tetradecane (D30, 98%) CD3(CD2)12CD3 1 g629-59-4fl 5 g

DLM-671 n-Tetradecylamine (D29, 98%) CD3(CD2)13NH2 1 g2016-42-4fl





HOOC COOH

C6D5

C6D5

O

OH

H

H

H

1

2

3

4

46 47

DLM-6109 1,1,3,3-Tetraethoxypropane (1,3-D2, 95%) 0.05 g122-31-6fl 0.1 g

O

O

O

O

1

3

NLM-160 Theophylline (1,3-15N2, 98%) 0.05 g58-55-9fl

HN

NNO

N

O

2

*

*

CNLM-444 Theophylline (2-13C, 99% ; 1,3-15N2, 98%) *CC6H8*N2N2O2 0.05 g58-55-9fl

CLM-447 L-Threonine (1-13C, 99%) CH3CH(OH)CH(NH2)*COOH on request72-19-5fl

CLM-2261 L-Threonine (U-13C4, 98%) *CH3*CH(OH)*CH(NH2)*COOH 0.1 g72-19-5fl 0.25 g 0.5 g NLM-742 L-Threonine (15N, 98%) CH3CH(OH)CH(*NH2)COOH 0.25 g80681-09-0

CNLM-587 L-Threonine (U-13C4, 98% ; 15N, 98%) *CH3*CH(OH)*CH(*NH2)*COOH 0.1 g72-19-5fl 0.25 g 0.5 g

DLM-1175 Toluene (methyl-D3, 98%) C6H5CD3 1 g1124-18-3 5 g

DLM-1176 Toluene (ring-D5, 98%) C6D5CH3 1 g108-88-3fl 5 g

DLM-1842 Tricine (D8, 98%) (HOCD2)3CNHCD2COOH 0.1 g5704-04-1fl (N-[tris(hydroxymethyl)methyl]glycine)

DLM-4779 Trimethylamine N-Oxide (D9, 98%) 1 g62637-93-8fl

N+

CD3

D3C

CD3

O-

CLM-350 Tripalmitin (2,2,2-13C3, 99%) (C14H29*CH2COO)3C3H5 0.1 g555-44-2fl

DLM-6686 Tris(2-carboxyethyl)phosphine•DCl (D16, 98%) P(CD2CD2COOD)3•DCl 0.25 g51805-45-9fl (TCEP)

DLM-1814 Tris(hydroxymethyl)methylamine (D11, 98%) D2N(CD2OD)3 5 g77-86-1fl (TRIS)

DLM-3593 Tris(hydroxymethyl)methylamine (D11, 98%) C4D11NO3 10 mL77-86-1fl (1m solution in D2O) (of soln.)

CLM-778 L-Tryptophan (1-13C, 99%) 0.25 g73-22-3fl

NH

2

34

COOH

NH2

*

CLM-1543 L-Tryptophan (indole-2-13C, 98%) (C8H5NH)CH2CH(NH2)COOH 0.25 g73-22-3fl

DLM-1092 L-Tryptophan (indole-D5, 98%) (C8D5NH)CH2CH(NH2)COOH 0.5 g73-22-3fl

NLM-800 L-Tryptophan (15N2, 98%) (C8H5*NH)CH2CH(*NH2)COOH 0.25 g73-22-3fl 0.5 g

CNLM-2475 L-Tryptophan (U-13C11, 98% ; U-15N2, 98%) (*C8H5*NH)*CH2*CH(*NH2)*COOH 0.1 g73-22-3fl Chemical Purity : 95%

CNLM-6077 L-Tryptophan-N-FMOC (*C8H5*NH)*CH2*CH(*NH-FMOC)*COOH 0.1 g35737-15-6fl (U-13C11, 98% ; U-15N2, 98%)

CLM-776 L-Tyrosine (1-13C, 99%) HOC6H4CH2CH(NH2)*COOH 1 g110622-46-3 (4-hydroxyphenyalanine)

CLM-437 L-Tyrosine (2-13C, 99%) HOC6H4CH2*CH(NH2)COOH 0.1 g60-18-4fl 0.25 g

CLM-3378 L-Tyrosine (3-13C, 99%) HOC6H4*CH2CH(NH2)COOH 0.1 g60-18-4fl 0.25 g

CLM-622 L-Tyrosine (phenol-4-13C, 97%) 0.25 g60-18-4fl

COOH

NH2HO *

CLM-623 L-Tyrosine (phenol-3,5-13C2, 99%) 0.25 g60-18-4fl

COOH

NH2HO

*

*

CLM-1542 L-Tyrosine (ring-13C6, 99%) HO*C6H4CH2CH(NH2)COOH 0.25 g60-18-4fl CLM-2263 L-Tyrosine (U-13C9, 98%) HO*C6H4*CH2*CH(NH2)*COOH 0.1 g55443-60-2 0.25 g 0.5 g

DLM-2317 L-Tyrosine (3,3-D2, 98%) HOC6H4CD2CH(NH2)COOH 0.5 g60-18-4fl 1 g

DLM-449 L-Tyrosine (ring-3,5-D2, 98%) HOC6D2H2CH2CH(NH2)COOH 1 g30811-19-9 5 g

DLM-451 L-Tyrosine (ring-D4, 98%) HOC6D4CH2CH(NH2)COOH 0.5 g62595-14-6 1 g

DLM-2303 L-Tyrosine-N-t-BOC, C6H5CH2OC6D4CH2CH(NH-t-BOC)COOH 0.25 g54784-93-9fl O-Benzyl ether (ring-D4, 98%) NLM-590 L-Tyrosine (15N, 98%) HOC6H4CH2CH(*NH2)COOH 0.5 g35424-81-8

NLM-1906 L-Tyrosine-N-t-BOC, C6H5CH2OC6H4CH2CH(*NH-t-BOC)COOH 0.25 g54784-43-9fl O-Benzyl ether (15N, 98%)

CNLM-439 L-Tyrosine (U-13C9, 98% ; 15N, 98%) HO*C6H4*CH2*CH(*NH2)*COOH 0.1 g60-18-4fl 0.25 g 0.5 g





48 49

CNLM-4349 L-Tyrosine-N-FMOC, O-t-Butyl Ether (CH3)3CO*C6H4*CH2*CH(*NH-FMOC)*COOH 0.1 g71989-38-3fl (U-13C9, 98% ; 15N, 98%) 0.25 g

UCLM-311 Urea (13C, 99%) H2N*CONH2 1 g58069-82-2 DLM-1269 Urea (D4, 98%) D2NCOND2 25 g1433-11-0

NLM-233-10 Urea (15N2, 10%) H2*NCO*NH2 25 g2067-80-3

NLM-233 Urea (15N2, 98%) H2*NCO*NH2 1 g2067-80-3 5 g

OLM-655 Urea (18O, 95%) H2NC*ONH2 1 g3138-51-0

CNLM-234 Urea (13C, 99% ; 15N2, 98%) H2*N*CO*NH2 0.5 g78405-35-3

VCLM-470 L-Valine (1-13C, 99%) (CH3)2CHCH(NH2)*COOH 1 g81201-85-6

CLM-3050 L-Valine (2-13C, 99%) (CH3)2CH*CH(NH2)COOH 0.25 g72-18-4fl

CLM-2249 L-Valine (U-13C5, 98%) (*CH3)2*CH*CH(NH2)*COOH 0.25 g72-18-4fl 0.5 g 1 g

DLM-488 L-Valine (D8, 98%) (CD3)2CDCD(NH2)COOH 0.25 g35045-72-8 0.5 g

NLM-316 L-Valine (15N, 98%) (CH3)2CHCH(*NH2)COOH 0.5 g59935-29-4 1 g

NLM-2060 L-Valine-N-t-BOC (15N, 98%) (CH3)2CHCH(*NH-t-BOC)COOH 0.5 g13734-41-3fl 1 g

NLM-4243 L-Valine-N-FMOC (15N, 98%) (CH3)2CHCH(*NH-FMOC)COOH 1 g68858-20-8fl

CNLM-442 L-Valine (U-13C5, 98% ; 15N, 98%) (*CH3)2*CH*CH(*NH2)*COOH 0.25 g72-18-4fl 0.5 g 1 g

CNLM-4348 L-Valine-N-FMOC (U-13C5, 98% ; 15N, 98%) (*CH3)2*CH*CH(*NH-FMOC)*COOH 0.1 g68858-20-8fl 0.25 g

CLM-779 Vanillin (carbonyl-13C, 90-95%) 0.1 g121-33-5fl 0.25 g

CHO

O

OH

*

WOLM-782-10 Water (17O, 10%) H2*O 1 g7732-18-5fl

OLM-782-20 Water (17O, 20%) H2*O 1 g7732-18-5fl

OLM-782-40 Water (17O, 35-40%) H2*O 1 g7732-18-5fl

OLM-782-70 Water (17O, 70%) H2*O 0.5 g7732-18-5fl

O186P Water (18O, 10%) H2*O on request7732-18-5fl

O188P Water (18O, 95%) H2*O on request7732-18-5fl

XDLM-2398 m-Xylene (D10, 98%) C6D4(CD3)2 5 g116601-58-2 FLAmmABLe LiquiD

CLM-1140 D-Xylose (1-13C, 99%) HOCH2(CHOH)3*CHO 0.25 g70843-21-7 0.5 g 1 g

CLM-1524 D-Xylose (2-13C, 99%) HOCH2(CHOH)2(*CHOH)CHO 0.25 g58-86-6fl 0.5 g 1 g

CLM-1219 D-Xylose (5-13C, 99%) HO*CH2(CHOH)3CHO 0.25 g58-86-6fl 0.5 g 1 g





BiomolecularNMR Products

50

53 52

Amino Acid MixturesThe cells are harvested and the lipids, pigments and carbohydrates are removed resulting in a mixture of about 95% free amino acids and approximately 5% unhydrolyzed protein. The typical amino acid content/profile is shown above under Cell Free Media — these materials are the algal amino acid mixture products (16AA).

Cell Free Media

EURISO-TOP® is pleased to offer seve-ral amino acid products for use in cell free systems. Cell free biosynthesis of proteins offers several advantages over the more traditional over-expression of proteins by cells. This method allows for the expression of proteins which may be toxic or prone to pro-teolytic degradation, as well as giving the researcher great flexibility in the production of stable isotope labeled proteins. Our amino acid mixes allow for the production of uniformly labeled proteins, while our individually labeled amino acids provide the opportunity for partial or custom labeling of specific residues.We offer both 16 amino acid mixtures (Algal Amino Acid Mixture) and 20 amino acid mixtures (“Cell Free” Amino Acid Mixture) in several labeling patterns.

Algal Products

Algal products are made by a proprie-tary process of growing algae in the presence of 13CO2, K15NO3, or D2O, depending upon the desired label. The products we offer reflect different processing levels of the material and their different applications.


EURISO-TOP® invites requests for quantity discounts and for custom synthesis

B I O M O L E C U L A R N M R P R O D U C T S

Bio-Express-2000 for Insect Cells and the Baculovirus ExpressionVector System (BEVS)

Many interesting proteins cannot be expressed in their native state by bacte-rial systems. In particular, glycosylated proteins are difficult to label isoto-pically and study. CIL has developed media for use in insect cell growth and the Baculovirus Expression Vector System (BEVS). CIL’s Bio-Express-2000 has shown itself to be an effective medium for the growth and expression of heterologous proteins in Spodoptera frugiperda (Sf-9) cells using the BEVS. It is a fully- rich serum-free medium containing amino acids along with carbohydrates. This medium, like Bio-Express-1000 for bacterial expression systems, requi-res no supplementation. It is available labeled in both 15N and 13C/15N. However, the researcher should be aware that certain amino acids in the media, including cystine, are unlabeled. Bio-Express-2000 is available as a dry powder which will reconstitute to 1L. Unlabeled samples are also available for evaluation and optimization.

In recent years there has been an increase in the applications of stable isotopes in biomolecular NMR studies. If you require a specific compound not lis-ted in this section, please contact our Customer Service Department for assistance.

Products listed in this section inclu-de : Bio-Express Cell Growth Media ; and algal amino acid mixtures. Please refer to the Research Compounds sec-tion for our listing of Amino Acids, Minimal media Substrates, Buffers and Detergents.

Bio-Express-1000 for Bacterial Expression Systems

The advent of isotope labeling tech-niques coupled with multidimensional NMR approaches has led to an explo-sion of structural information in protein chemistry. In the 1990s, CIL’s Bio-Express-1000 Cell Growth Media ushered in a new generation of pos-sibilities by supplying bacterial cells with the labeled nutrients required for optimum growth and expression of proteins. Any combination of 13C, 15N and D labeling is available, giving the researcher maximum flexibility for experimental design. Bio-Express-1000, a rich medium, requiring no supplementation is sold as a sterile concentrate (10x), ready to be diluted and inoculated. 100mL of concentrate will produce approxi-mately 1L of medium. Each lot of Bio-Express-1000 is fully analyzed to monitor lot-to-lot variability. The lots

are tested for growth using different strains of bacteria. They are also ana-lyzed by HPLC for amino acid content and by GC/MS for isotopic enrich-ment. With these analytical data, lot-to-lot variations can be monitored and reported. Although differences are expected to be minimal, lot-to-lot variability is normal. 10mL samples (equivalent to 100mL of medium) of unlabeled medium are available.

Bio-Express-Min

Bio-Express-Min, a fortified minimal medium, is a less expensive alternative for growth and expression in bacterial systems. By providing some amount of essential nutrients along with substantial carbohydrates (4-5g/L), Bio-Express-Min delivers more than double the growth seen in traditional minimal media. Bio-Express-Min is delivered as sterile concentrate (10x) ready to be diluted and inoculated. No further augmentation of the media is normally necessary.

Bio-Express-1000 as a Spike

Our Bio-Express-1000 media may be used as a supplement to mini-mal media to decrease the time and expense involved in growing the lar-ger cultures needed for production of sufficient quantities of labeled protein. CIL has provided pricing for 10mL sample sizes of our Bio-Express-1000 products.


EURISO-TOP® invites requests for quantity discounts and for custom synthesis


Profiles for Amino Acid MixturesApproximate percentages, subject to variability.

16AA 20AA

L-Alanine 7% L-Alanine 6% L-Arginine 7% L-Arginine 6% L-Aspartic Acid 10% L-Aspartic Acid 8% L-Glutamic Acid 10% L-Glutamic Acid 9% Glycine 6% Glycine 5% L-Histidine 2% L-Histidine 1% L-Isoleucine 4% L-Isoleucine 3% L-Leucine 10% L-Leucine 9% L-Lysine 14% L-Lysine 12% L-Methionine 1% L-Methionine 1% L-Phenylalanine 4% L-Phenylalanine 4% L-Proline 7% L-Proline 5% L-Serine 4% L-Serine 4% L-Threonine 5% L-Threonine 4% L-Tyrosine 4% L-Tyrosine 3% L-Valine 5% L-Valine 4% L-Asparagine 5% L-Cysteine 3% L-Glutamine 5% L-Tryptophan 3%

55

CGM-1000-DN-S Bio-Express-1000 (U-D, 98% ; U-15N, 98%) (10 x Concentrate) 10 mL

CGM-1000-CDN Bio-Express-1000 (U-13C, 98% ; U-15N, 98% ; U-D, 98%) (10 x Concentrate) 100 mL

CGM-1000-CDN-S Bio-Express-1000 (U-13C, 98% ; U-15N, 98% ; U-D, 98%) (10 x Concentrate) 10 mL

CGM-2000-U Bio-Express-2000 (Unlabeled) on request

CGM-2000-N Bio-Express-2000 (U-15N, 92-95%) on request

CGM-2000-CN Bio-Express-2000 (U-13C, 92-95% ; U-15N, 92-95%) on request

CGM-3000-CN Bio-Express-Min (U-13C, 98% ; U-15N, 98%) (10 x Concentrate) 100 mL

CGM-3000-CN-S Bio-Express-Min (U-13C, 98% ; U-15N, 98%) (10 x Concentrate) 10 mL


Please inquire about quantity discounts

54

CLM-1548 Algal Amino Acid Mixture (16AA) (U-13C, 98%) 0.5 g 1 g

DLM-2082-80 Algal Amino Acid Mixture (16AA) (U-D, 80%) on request

NLM-2161 Algal Amino Acid Mixture (16AA) (U-15N, 98%) 0.5 g 1 g

CNLM-452 Algal Amino Acid Mixture (16AA) (U-13C, 98% ; U-15N, 98%) 0.5 g 1 g

DNLM-819 Algal Amino Acid Mixture (16AA) (U-D, 98% ; U-15N, 98%) on request

CDNLM-2496 Algal Amino Acid Mixture (16AA) (U-13C, 98% ; U-D, 98% ; U-15N, 98%) 0.5 g

DLM-6819 “Cell Free” Amino Acid Mix (20AA) (U-D, 98%) on request

NLM-6695 “Cell Free” Amino Acid Mix (20AA) (U-15N, 98%) 1 g

CNLM-6696 “Cell Free” Amino Acid Mix (20AA) (U-13C, 98% ; U-15N, 98%) 1 g

DNLM-6818 “Cell Free” Amino Acid Mix (20AA) (U-D, 98% ; U-15N, 98%) on request

CDNLM-6784 “Cell Free” Amino Acid Mix (20AA) (U-13C, 98% ; U-15N, 98% ; U-D, 98%) 0.5 g

CGM-1000-U Bio-Express-1000 (Unlabeled) (10 x Concentrate) 100 mL

CGM-1000-U-S Bio-Express-1000 (Unlabeled) (10 x Concentrate) 10 mL CGM-1000-C Bio-Express-1000 (U-13C, 98%) (10 x Concentrate) 100 mL CGM-1000-C-S Bio-Express-1000 (U-13C, 98%) (10 x Concentrate) 10 mL

CGM-1000-D Bio-Express-1000 (U-D, 98%) (10 x Concentrate) 100 mL CGM-1000-D-S Bio-Express-1000 (U-D, 98%) (10 x Concentrate) 10 mL

CGM-1000-N Bio-Express-1000 (U-15N, 98%) (10 x Concentrate) 100 mL

CGM-1000-N-S Bio-Express-1000 (U-15N, 98%) (10 x Concentrate) 10 mL

CGM-1000-CD Bio-Express-1000 (U-13C, 98% ; U-D, 98%) (10 x Concentrate) 100 mL

CGM-1000-CN Bio-Express-1000 (U-13C, 98% ; U-15N, 98%) (10 x Concentrate) 100 mL

CGM-1000-CN-S Bio-Express-1000 (U-13C, 98% ; U-15N, 98%) (10 x Concentrate) 10 mL

CGM-1000-DN Bio-Express-1000 (U-D, 98% ; U-15N, 98%) (10 x Concentrate) 100 mL


Please inquire about quantity discounts

Catalog # Compound Amount


IsotopicGases

56

58 (1) Some of our isotopic gases are packed in American standard cylinders which are different from the European Standard. They have in general an outlet that allows fitting. These cylinders can be used only under certain conditions which will be conveyed by the sales department.

Cylinders - Technical data

Metallic Maximum Diameter Height at Height with Weight Geometrical cylinder pressure the tap axis the cap on volume description (bar) (mm) (mm) (mm) (kg) (L)

B50 200 245 1 370 1 480 72 to 75 50 Steel to 1 560 to 1 680

B50 200 250 1 530 1 630 50 40 to 55 Light Alloy

B5 200 145 510 620 7 5 Light Alloy

B1 200 76 345 422 1.7 1 Light Alloy

B05 200 76 190 272 1.3 0.5 Light Alloy

Packaging information

a - Cylinders :

Most isotopic gases are delivered in metallic cylinders complying with the European Standards. These cylinders become the property of the user and can be re-used under certain conditions.Weight, height & maximum pressure measures are given in the table below (approximate indications).

b - Breakseal glass flasks :

Breakseal glass (Pyrex or Silicon) flasks are used for adding a gas directly to a reaction by breaking the seal while the breakseal is connected to the reaction by tubing.They are used for many gases in small quantities, 10 mL to 1 L with a pig tail (tube Ø 12).

Gas Mixtures

EURISO-TOP® can make all gases mixtures, with different components and concentrations, if chemically compatible.

EURISO-TOP® uses gravimetric or volumetric methods depending on the type of the mixture and the precision requested by the customer ; generally EURISO-TOP® provides a mixture with a precision of 0.5 to 5%.

The volume tolerance of each gas will be less than 5% in the mixture. EURISO-TOP® can offer the analysis of the mixture by mass spectrometry.

Isotopic Gases Packaging

Gas Cylinder Vol. Material Tap Outlet Max quantity (L) type (L)/cylinder

Acetylene B05 0.5 Light Alloy Brass e 1 B1 1 Light Alloy Brass e 25

Ammonia B05 0.5 Light Alloy Stainless Steel C 350 B1 1 Light Alloy Stainless Steel C 700

Argon B0.5 0.5 Light Alloy Brass C 80 B1 1 Light Alloy Brass C 160 (1) - - - - -

Carbon B0.5 0.5 Light Alloy Brass C 200 Dioxide B1 1 Light Alloy Brass C 400

Carbon B0.5 0.5 Light Alloy Brass e 50 Monoxide B1 1 Light Alloy Brass e 100

Deuterium B1 1 Light Alloy Brass e 100 B5 5 Light Alloy Brass e 500 B50 40-55 Light Alloy Brass e 8,000 Carbon Steel 10,000

Deuterium B0.5 0.5 Light Alloy Brass e 50 Hydride B1 1 Light Alloy Brass e 100

Ethane Light Alloy Brass e 90

Helium-3 B0.5 0.5 Light Alloy Brass C 50 B1 1 Light Alloy Brass C 100

Krypton B0.5 0.5 Light Alloy Brass C 50 B1 1 Light Alloy Brass C 100 (1) - - - - -

Methane B0.5 0.5 Light Alloy Brass e 80 B1 1 Light Alloy Brass e 160 (1) - - - - -

Neon B0.5 0.5 Light Alloy Brass C 50 B1 1 Light Alloy Brass C 100 (1) - - - - -

Nitrogen B05 0.5 Light Alloy Brass C 75 B1 1 Light Alloy Brass C 150

Oxygen B0.5 0.5 Light Alloy Brass F 80 B1 1 Light Alloy Brass F 160

Xenon B0.5 0.5 Light Alloy Brass C 20 B1 1 Light Alloy Brass C 50 (1) - - - - -

59

I S O T O P I C G A S E SI S O T O P I C G A S E S

Type C male outlet Ø 21.70 mm Right thread 1.814 mm Type E male outlet Ø 21.70 mm Left thread 1.814 mm Type F Female outlet Ø 22.91 mm Right thread 1.814 mm

61 60

Compound Isotopic Code Amount Cylinders enrichment (liters) (atom %)

I S O T O P I C G A S E S I S O T O P I C G A S E S

Please enquire about quantity discount

ACETYLENE Flammable Gas, Toxic, Non Corrosive Cargo Aircraft Only ; uN 1001 Maximum packaging pressure is 1 atmosphere

Acetylene [1,2 -12C2] 99,96 CLm-1163 on request

Acetylene [1,2 -13C2] 99 CLm-107 on request

Acetylene [D2] 99 DLm-322 on request

AMMONIA Toxic gas & Corrosive Cargo Aircraft Only ; uN 1005

Ammonia [D3] 99 Ge006 10 / 25 / 50 B05 - B1

Ammonia [15N] 10 GA006-10 10 B05 99 GA006-99 1 B05

ARGON Non Flammable gas, Non Toxic Passenger and Cargo Aircraft ; uN 1006

Argon 36 (Natural abundance : 0,337 atom %) > 99.5 GAR36 on request

Argon 38 (Natural abundance : 0,063 atom %) > 95 GAR38 on request

Argon 40 (Natural abundance : 99,6 atom %) > 99.95 GAR40 on request

1,3-BUTADIENE Flammable Gas Cargo Aircraft Only ; uN 1010 Stabilized with hydroquinone

1,3-Butadiene [1, 1, 4, 4-D4] 98 DLm-877 on request

1,3-Butadiene [D6] 98 DLm-876 on request

n-BUTANE Flammable Gas Cargo Aircraft Only ; uN 1011

n-Butane [D10] 98 DLm-1610 on request

CARBON DIOXIDE Non Flammable gas, Toxic, Non Corrosive Passenger & Cargo Aircraft ; uN 1013

Carbon dioxide [12C] 99,99 GC1215 5 /25 B05 - B1

Carbon dioxide [13C] 10 GC15-10 50 /250 B1* contains less than 1,0% 18O 99 GC15-99 1 /15 B05 - B1

Carbon dioxide [18O2] 97-98 GO15 on request

CARBON MONOXIDE Toxic gas & Flammable gas Cargo Aircraft Only ; uN 1016

Carbon Monoxide [12C] 99,99 GC1217 5 / 25 B05 - B1

Carbon Monoxide [13C] 99 GC17 1 / 5 B05 - B1 * contains less than 1% 18O

Carbon Monoxide [18O] 97 / 98 GO17 on request

CHLOROETHANE Flammable gas Cargo Aircraft Only ; uN 1037

Chloroethane [D5] 99 DLm-1171 on request

CHLOROMETHANE Flammable gas Cargo Aircraft Only ; uN 1063

Chloromethane [13C] 99 CLm-339 on request

Chloromethane [D3] 99 DLm-337 on request

DEUTERIUM Flammable gas, Toxic, Non Corrosive Cargo Aircraft Only ; uN 1957

Deuterium [D2] ≥ 99.8 Ge026 100 / 500 B1 - B5Tritium < 0.025 µCi/l > 8500 B50 D2O < 75 ppm ; O2 < 10 ppm ; N2 < 10 ppm

DEUTERIUM HYDRIDE Flammable, Toxic, Non Corrosive Cargo Aircraft Only ; uN 1049

Deuterium Hydride [HD] 97 DLm-194 1 / 5 / 10 B05 - B1

DIMETHYLAMINE Flammable Gas Cargo Aircraft Only ; uN 1032

Dimethylamine [D6] 99 Ge039 on request B05

ETHANE Flammable Gas, Toxic, Non Corrosive Cargo Aircraft Only ; uN 1035

Ethane [D6] 98 Ge045 1 B05

Ethane [1-13C] 99 CLm-2187 on request



63 62Please enquire about quantity discount



I S O T O P I C G A S E S I S O T O P I C G A S E S

METHANE Flammable Gas, Toxic, Non Corrosive Cargo Aircraft Only ; uN 1971

Methane [12C] 99,99 CLm-427 on request

Methane [13C] 99 GC67-99 0,1 / 1 B05 - B1 99,9 GC67-100 0,1 / 1 B05 - B1

Methane [D1] 98 DLm-1257 on request



Methane [D4] 99 Ge67 1 / 5 / 10 / 25 B05-B1

Methane [12C,D4] 12C : 99,95-D4 : 98 DLm-1616 on request

METHYLAMINE Flammable Gas Cargo Aircraft Only ; uN 1061

Methylamine [D3] 98 DLm-1500 on request

Methylamine [D5] 98 DLm-1501 on request

METHYL VINYL ETHER Flammable Gas Cargo Aircraft Only ; uN 1087

Methyl Vinyl Ether (methyl-D3) 98 DLm-1623 on request

NEON Non Flammable Gas, Non Toxic, Non Corrosive Passenger & Cargo Aircraft ; uN 1065

Neon 20 (Natural abundance : 90,92 atom %) > 99.95 GNe20 on request

Neon 21 (Natural abundance : 0,257 atom %) 90 GNe21 on request

Neon 22 (Natural abundance : 8,82 atom %) > 99.9 GNe22 on request

NEON 20 / NEON 22 mixture (20Ne, 50 ; 22Ne, 50) > 99 GNe20-22 on request

NEON 20 / NEON 22 / HELIUM-3 mixture > 99 GHe36 on request

NITROGEN Non Flammable Gas, Non Toxic, Non Corrosive Passenger & Cargo Aircraft ; uN 1066

Nitrogen [15N2] 99 GA087 1 B05

OXYGEN Non Flammable Gas & Oxidizer, Non Toxic, Non Corrosive Passenger & Cargo Aircraft ; uN 1072

Oxygen 16 [16O2] 99,98 GOX16 on request

Oxygen 17 [17O2] Please inquire GOX17 on request

Oxygen 18 [18O2] 95-98 GOX18 1 B05

ETHYLENE Flammable Gas Cargo Aircraft Only ; uN 1962

Ethylene [13C2] 99 CLm-415 on request

Ethylene [cis-1,2-D2] 98 DLm-1530 on request

Ethylene [trans-1,2-D2] 98 DLm-740 on request

Ethylene [D4] 98 DLm-347 on request

FLUOROMETHANE Flammable Gas Cargo Aircraft Only ; uN 2454

Fluoromethane [13C] 99 CLm-1014 on request

Fluoromethane [D3] 99 DLm-1015 on request

HELIUM-3 Non Flammable Gas, Non Toxic, Non Corrosive Passenger & Cargo Aircraft ; uN 1046

Cryogenic grade > 99.8 GHe31 on request

Standard grade > 99.95 GHe32 on request

Neutron detection grade > 99.99 GHe33 on request

High purity grade > 99.995 GHe34 on request

Typical chemical composition Cryogenic Standard Neutron High purity

Total Helium (4He + 3He) atom % > 99,9 > 99,99 > 99,995 99,999 Helium 4 (atom %) < 0,2 < 0,05 < 0,01 < 0,009 Tritium (atom %) < 1 x 10-11 < 1 x 10-11 < 1 x 10-11 < 1 x 10-11 Oxygen, Nitrogen, CO2, Argon, Other (%) < 1 < 0,1 < 0,01 < 0,005

HELIUM-3 / NEON 20 / NEON 22 mixture > 99 GHe36 on request

HYDROGEN or PROTIUM Flammable Gas, Toxic, Non Corrosive Cargo Aircraft Only ; uN 1049

Hydrogen, Deuterium Depleted (< 15 ppm HD) DLm-1247 on request

KRYPTON Non Flammable Gas, Non Toxic, Non Corrosive Passenger & Cargo aircraft ; uN 1056

Krypton 78 (Natural abundance : 0,35 atom %) > 99,5 GKR78 on request







64


PROPANE Flammable Gas Cargo Aircraft Only ; uN 1978

Propane (1-13C) 99 CLm-403 on request

Propane [D8] 98 DLm-153 on request

PROPENE Flammable Gas Cargo Aircraft Only ; uN 1077

Propene (3-13C) 99 CLm-1514 on request

Propene (3-3-3-D3) 98 DLm-1626 on request

Propene (D6) 98 DLm-304 on request

PROTIUM See Hydrogen

TRIMETHYLAMINE Flammable Gas Cargo Aircraft Only ; uN 1083

Trimethylamine (D9) 98 DLm-603 on request

VINYL CHLORIDE Flammable Gas Cargo Aircraft Only ; uN 1086 Stabilized with hydroquinone

Vinyl Chloride (D3) 98 DLm-167 on request

XENON Non Flammable Gas, Non Toxic, Non Corrosive Passengers & Cargo Aircraft ; uN 2036

Xenon 124 (Natural abundance : 0,097 atom %) > 99 GXe124 on request









IsotopicMetals

I S O T O P I C G A S E S

C : Carbonate, Cl : Chloride, M : Metal, O : Oxide, S : Na Salts

66

Gallium 69Ga m mGA69

Gallium 71Ga m mGA71

Germanium 70Ge m/O mGe70





Hafnium 174Hf O mHF174






Indium 113in m miN113

Indium 115in m miN115

Iridium 191ir m miR191

Iridium 193ir m miR193

Iron 54Fe m/O mFe54

Iron 56Fe m mFe56

Iron 57Fe m/O mFe57

Iron 58Fe m/O mFe58

Lanthanum 138La O mLA138

Lanthanum 139La O mLA139

Lead 204Pb m mPB204

Lead 206Pb m mPB206

Lead 207Pb m mPB207

Lead 208Pb m mPB208

Lithium 6Li page 70

Lithium 7Li page 70

Lutetium 175Lu O mLu175

Lutetium 176Lu O mLu176

Magnesium 24mg O mmG24

Magnesium 25mg m/O mmG25

Magnesium 26mg O mmG26

Mercury 196Hg m mHG196






Molybdenum 92mo m/O mmO92

Molybdenum 94mo O mmO94






Neodynium 142Nd O mND142







Nickel 58Ni m mNi58

Nickel 60Ni m/O mNi60

Nickel 61Ni m mNi61



Element Isotope Form Code Element Isotope Form Code

Chlorine 35Cl S mCL35

Chlorine 37Cl S mCL37

Chromium 50Cr m/O mCR50

Chromium 52Cr m mCR52

Chromium 53Cr O mCR53

Chromium 54Cr O mCR54

Copper 63Cu m mCu63

Copper 65Cu m mCu65

Dysprosium 156Dy O mDy156







Erbium 162er O meR162






Europium 151eu O meu151

Europium 153eu O meu153

Gadolinium 152Gd O mGD152







Element Isotope Form Code Element Isotope Form Code

Antimony 121Sb m mSB121

Antimony 123Sb m mSB123

Barium 130Ba C mBA130







Boron 10B m/O mB10

Boron 11B m/O mB11

Bromine 79Br S mBR79

Bromine 81Br S mBR81

Cadmium 106Cd m mCD106








Calcium 40Ca C mCA40






Cerium 136Ce O mCe136



Cerium 142Ce O mCe142 67

I S O T O P I C M E T A L SI S O T O P I C M E T A L S

Please inquire about quantity discounts Please inquire about quantity discounts C : Carbonate, Cl : Chloride, M : Metal, O : Oxide, S : Na Salts

C : Carbonate, Cl : Chloride, M : Metal, O : Oxide, S : Na SaltsC : Carbonate, Cl : Chloride, M : Metal, O : Oxide, S : Na Salts

68Please enquire about quantity discount

Samarium 144Sm O mSm144







Selenium 74Se m mSe74






Silicon 28Si O mSi28



Silver 107Ag m mAG107

Silver 109Ag m mAG109

Strontium 84Sr C mSR84




Sulfur 32S m mS32

Sulfur 33S m mS33

Sulfur 34S m mS34

Sulfur 36S m mS36

Tellurium 120Te m mTe120

Tellurium 122Te m/O mTe122


Tellurium 124Te m/O mTe124





Thallium 203Tl m/O mTL203

Thallium 205Ti m mTL205

Tin 112Sn m mSN112

Tin 114Sn m mSN114

Tin 115Sn m mSN115

Tin 116Sn m mSN116

Tin 117Sn m mSN117

Tin 118Sn m mSN118

Tin 119Sn m mSN119

Tin 120Sn m mSN120

Tin 122Sn m mSN122

Tin 124Sn m mSN124

Titanium 46Ti m mTi46




Tungsten 180W m mW180





Vanadium 50v O mv50

Ytterbium 168yb O myB168







Zinc 64Zn m mZN64

Zinc 66Zn m mZN66

Zinc 67Zn m mZN67

Zinc 68Zn m mZN68

Zinc 70Zn m mZN70

Zirconium 90Zr O mZR90





Element Isotope Form Code Element Isotope Form CodeElement Isotope Form Code Element Isotope Form Code

Osmium 184Os m mOS184







Palladium 102Pd m mPD102






Platinium 190Pt m mPT190






Potassium 39K Cl mK39



Rhenium 185Re m mRe185

Rhenium 187Re m mRe187

Rubidium 85Rb Cl mRB85

Rubidium 87Rb Cl/O mRB87

Ruthenium 98Ru m mRu98






I S O T O P I C M E T A L SI S O T O P I C M E T A L S

69

LITHIUM-6

Li-6 Carbonate ≥ 95 mLi 6 CP 200 g mLi 6 Cq 1 kg

Li-6 Fluoride ≥ 95 mLi 6 FP 50 g

Li-6 Hydroxide, H2O ≥ 95 mLi 6 HP 50 g

Li-6 Metal (4-9 g ingots) ≥ 95 mLi 6 mP 1 g

Li-6 Sulfate ≥ 95 mLi 6 SP 50 g

LITHIUM-7

Li-7 Carbonate ≥ 99 mLi 7 CP 50 g

Li-7 Fluoride ≥ 99 mLi 7 FP 50 g

Li-7 Hydroxide, H2O ≥ 99 mLi 7 HP 100 g

Li-7 Metal (21-27 g ingots) ≥ 99 mLi 7 mP 1 g

Element Isotopic Code Quantity enrichment (atom %)

Lithium-6 and 7

Carbon-13 Breath TestSubstrates

70

I S O T O P I C M E T A L S


73 72

Code Substrate Form Unit Evaluation

H. pylori detection and eradication control

HELICOBACTER PYLORI

INC670P Urea [13C] - Pharmaceutical grade bulk dry powder gram (european Pharmacopoiea)

INC670P75 Urea [13C]- Pharmaceutical grade 75 mg dry powder tube 75 mg +/- 3 % Labelled tube (european Pharmacopoiea)

LIVER FUNCTION

INC507P Aminopyrine [N,N-dimethyl-13C2] bulk dry powder gram

INC507P140 Aminopyrine [N,N-dimethyl-13C2] 140 mg dry powder tube Cyt.P450

INC590P Methacetin bulk dry powder gram Cyt.P450 [N-(4-methoxy-13C-Phenyl) acetamide]

INC566P D-Galactose [1-13C] bulk dry powder gram quantification of the functional mass livrer

FAT MALABSORPTION

INC654P Trioctanoin [carboxyl-13C3] bulk liquid gram medium chain fatty acids triglycerides

INC656P Triolein [carboxyl-13C3] bulk liquid gram Steatorrhea

INC658P Tripalmitin [carboxyl-13C3] bulk powder gram Steatorrhea

GASTRIC EMPTYING

INC610P Octanoic acid [1-13C] bulk liquid gram

INC610P91 Octanoic acid [1-13C] 91 mg liquid tube Solid meal

INC643P Sodium octanoate [1-13C] bulk dry powder gram Solid meal

INC639P Sodium acetate [1-13C] bulk dry powder gram Liquid meal

ORO-CAECAL TRANSIT TIME (OCTT)

INC582P Lactosyl - ureide [13C-urea] bulk dry powder gram

INK579P Lactosyl - ureide [unlabelled] bulk dry powder gram OCTT measurement

PANCREATIC FUNCTION

INC650P Mixed Triglyceride bulk dry powder gram Lipasic activity [2-octanoyl [1-13C] - 1,3 distearoyl glycerol]

INC525P Cholesteryl-3-octanoate [1-13C] bulk dry powder gram Pancreatic exocrine insufficiency

Breath test substrates

Carbon-13 Breath tests constitute a new class of non-invasive diagnostic tests used in clinical medicine. They have been developed with the intention of simplifying traditional tests of metabolic functions The idea of diagnosing metabolic function by giving orally to patients a compound labelled with stable isotope (carbon-13) and collecting sample of their breath over a period of time is called “Breath Tests”.

Principle

Carbon-13 Breath tests have the common characteristic that the labelled substrate is given orally. The substrate bears a functional group in which a normally present 12C atom has been replaced by the stable isotope 13C (non radioactive). This functional group is cleaved enzymatically under specific circumstances, either during the absorption, or the gastro- intestinal transit, or the metabolisation of the absorbed substrate.

The key metabolic function is followed by measuring the increase of 13CO2 in the subject’s breath over a period of time.

Advantages

Carbon-13 Breath tests are a non invasive method which enable to measure gastro-intestinal, hepatological and meta-bolic functions directly in several physiological conditions.

Taking breath samples is a simple procedure

The use of 13C permits : - short term repeat of breath tests on the same

subject - the study of metabolic function in children and

during pregnancy

Labelled substrates

Several 13C-labelled substrates are highlighted hereafter to illustrate the applicability and utility of the C-13 Breath test. (The 13CO2 mixes with the body pool of CO2-HCO3 and is breathed out).

The exhalation of 13CO2 reflects the function we want to investigate.

13C-substrate 13CO2-breathFunction or enzyme

to be examined

EURISO-TOP®, the largest European producer of 13C-labelled substrates, is pleased to offer a wide variety of enriched substrates which can be used in clinical studies of metabolic disorders, bacterial infection and organ function.

We are pleased to assist you by providing technical information on applications and literature references.

All our 13C-Substrates are controlled with modern analytical methods and delivered with a complete Certificate of Analysis :

Chemical purity (≥99%) HPLC, 13C-NMR, 1H-NMR, assay...

Isotopic enrichment (≥99 atom %) mass spectrometry

Pyrogenicity Limulus test

European Pharmacopoeia (urea 13C)

Carbon-13Breath Test Substrates


EURISO-TOP® could supply information such as Drug Master File (DMF) to assist Clinical Researchers, under non-disclosure agreement. Our Quality Insurance Department can be contacted through your Sales Representative.

C A R B O N - 1 3 B R E A T H T E S T S U B S T R A T E S C A R B O N - 1 3 B R E A T H T E S T S U B S T R A T E S

Ordering information

EURISO-TOP invites requests for quantity discounts and for custom synthesis

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L A B E L L E D C O M P O U N D S

X X

O=13CH2O

NH2

NH2

O=13C

NH2

O-NH4+

H2OO=13C

O-NH4+

O-NH4+

13C Urea

H. pylori urease

Ammonium13C Carbamate

Ammonium13C Carbonate

13CO + NH3 (Autoclave)

13C Urea

Purificaton

EURISO-TOP® 13C Urea production is carefully control-led for water and ammonium contents to ensure the best stability : Water by Karl-Fisher titration and Eur.Ph. (loss on drying < 1 %), Ammonium by enzymatic reaction assay, indophenol blue

titration and Eur.Ph. (Nesler reagent limit test < 500 ppm).

Water can hydrolyse 13C-Urea to ammonium carbonate via ammonium carbamate which are not substrates for H. pylori.

13C Urea Production

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“Urea [13C, 99 %] produced by EURISO-TOP® is widely used for Helicobacter pylori detection and is the main component of HELI-KIT®”

13C Urea

Methanolic

impure solution

CLM-420-MG D-Glucose [1-13C] 99 % dry powder gram

IND570P D-Glucose [6,6-D2] 99 % dry powder gram

DLM-1229-SP Glycerol [1,1,2,3,3-D5] 98 % liquid gram

CLM-422-SP Glycine [1-13C] 99 % dry powder gram

INC586P L-Leucine [1-13C] 99 % dry powder gram

IND590P L-Leucine [5,5,5-D3] 99 % dry powder gram

CLM-150-SP Palmitic acid [1-13C] 99 % dry powder gram

DLM-1258-MG L-Phenylalanine [ring-D5] 98 % dry powder gram

INC620P L-Phenylalanine [1-13C] 99 % dry powder on request

INC640P Sodium Bicarbonate [13C] 99 % dry powder on request

OLM-240-10-SP 18-O enriched Water (unnormalized) 10 % liquid gram

Code Substrates IE (%) Form Unit

Other In vivo Isotopic Tracers

O T H E R I N V I V O I S O T O P I C T R A C E R S

EURISO-TOP® could supply information such as Drug Master File (DMF) to assist Clinical Researchers, under non-disclosure agreement. Our Quality Insurance Department can be contacted through your Sales Representative.

13CO2 Calibration Standards13 C O 2 C A L I B R A T I O N S T A N D A R D S

We offer a set of three carbon dioxide (CO2) standards for use in Carbon-13 (13C) breath test analysis. Extensive use of 13C breath test analyses in clinical diagnostic applications has created a need for certified reference standards. This set of standards is designed to mimic 13CO2 levels in normal breath (Baseline Calibrant) and in two enriched samples (Mid-Level and High-Level Calibrants). Each cylinder is filled with 10 liters of air containing 5% CO2. These gas calibration standards are gravimetrically prepared in our laboratories. Differences in 13C enrichment (expressed in delta units) between the samples were determined in a multi-center interlaboratory study based on Isotope Ratio Mass Spectrometry (IRMS) analyses.

CLM-3781 Baseline: Average Delta 13C vs. PDB from 10 L interlaboratory study. 50 L 5% CO2 in Air – Baseline Calibrant Gas with Delta value = -22.8 vs. PDB

CLM-3782 Mid-Level: 9.58 Delta units greater than Baseline. 10 L 5% CO2 in Air – mid-level Calibrant Gas at 50 L 9.58 Delta units above Baseline Calibrant Gas (CLm-3781) or Delta value = -13.22 vs. PDB

CLM-3783 High-Level: 15.5 Delta units greater than Baseline. 10 L 5% CO2 in Air – High-Level Calibrant Gas at 50 L 15.5 Delta units above Baseline Calibrant Gas (CLm-3781) or Delta value = -7.3 vs. PDB


Each 10L gas mixture is packaged in a standard 460 mL carbon steel lecture bottle fitted with a CGA 110/170 brass valve. Each 50L gas mixture is packaged in a standard 3L carbon steel cylinder fitted with a CGA 580 packless brass angle valve.

0

-5

-10

-15

-20

-25

Delta13CO2

High-LevelCalibrant(CLM-3783)

Mid-LevelCalibrant(CLM-3782)

BaselineCalibrant(CLM-3781)

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Euriso-top Stable Isotope complete catalogue

Documents

Transcript of Euriso-top Stable Isotope complete catalogue