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Signature

Name: Esen K. Akpek, MD Date: 1/5/2011

DEMOGRAPHIC INFORMATION

Current Appointments:

Johns Hopkins University School of Medicine, Johns Hopkins Hospital.

Johns Hopkins University School of Medicine, Bayview Medical Center.

Personal Data:

Business address: The Wilmer Eye Institute

Johns Hopkins Medical Institutions

600 N. Wolfe Street, Maumenee #317

Baltimore, MD 21287

Telephone: (410) 955 5214

Fax: (410) 614 6480

e-mail: esakpek@jhmi.edu

Education:

1990-1991 BS, Ankara Girls’ Lycee, Ankara, Turkey

1984-1985 English Preparatory School at Hacettepe

University Medical School, Ankara

1985-1990 MD, Hacettepe University Medical School, Ankara

Postdoctoral Training:

1990-1992 Intern in medicine, Hacettepe University

Medical School Hospital and Children’s

Hospital, Ankara

1992-1995 Residency in ophthalmology, Ankara Numune

Hospital, Ankara

2/1996-6/1996 Research fellow, Hilles Immunology Laboratory, Department

of Ophthalmology, Massachusetts Eye and Ear Infirmary,

Harvard Medical School, Boston

7/1996-6/1998 Clinical fellow, Ocular Immunology and Uveitis Service,

Department of Ophthalmology, Massachusetts Eye and Ear

Infirmary, Harvard Medical School, Boston

7/1998-6/1999 Clinical fellow, Cornea and External Disease Service,

Wilmer Eye Institute Department of Ophthalmology,

Johns Hopkins University School of Medicine, Baltimore

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Professional Experience:

1991-1992 General practitioner, Social Security Hospital, Ankara,

Turkey

1994-1995 Chief Resident in ophthalmology, Ankara Numune Hospital,

Ankara

1999-2000 Instructor in ophthalmology, Wilmer Eye Institute, Johns

Hopkins University Medical School, Baltimore

2000-2005 Assistant Professor in ophthalmology, Cornea and External

Disease Service, Wilmer Eye Institute, Johns Hopkins

University Medical School, Baltimore

2004-present Director, Ocular Surface Diseases and Dry Eye Clinic,

Wilmer Eye Institute, Johns Hopkins University Medical

School, Baltimore

2005-present Associate Professor of Ophthalmology, Cornea and External

Disease Service, Wilmer Eye Institute, Johns Hopkins

University Medical School, Baltimore

2009-present Associate Director of Sjogrens’ Syndrome Center, Johns

Hopkins at Bayview Medical Center, Baltimore, Maryland

2010-present Director, Cornea and External Disease Clinical Fellowship,

Wilmer Eye Institute, Johns Hopkins University Medical

School, Baltimore, Maryland

2011-present Associate Professor of Rheumatology,

RESEARCH ACTIVITIES

Publications:

Peer-reviewed scientific articles:

1. Utine CA, Tzu J, Akpek EK. Lamellar keratoplasty using gamma irradiated

corneal lenticules. Am J Ophthalmol 2011;151:170-174.

2. Zhang K, Akpek EK, Weblinger VP, et al. Noninvasive quality evaluation of

post-surgical clear corneal insicion via high resolution Fourier-domain optical

coherence tomography. Electronics Letters 2010;46;22.

3. Utine CA, Gehlbach PL, Zimmer-Galler I, Akpek EK. Permanent

Keratoprosthesis Combined With Pars Plana Vitrectomy and Silicone Oil

Injection for Visual Rehabilitation of Chronic Hypotony and Corneal Opacity.

Cornea 2010;Epub ahead of print.

4. Karp JK, Akpek EK, Anders RA. Autoimmune hepatitis in patients with

primary Sjogren’s syndrome: a series of two–hundred and two patients. In J Clin

Exp Pathol 2010;3:582-6.

5. Tay E, Utine CA, Akpek EK. Crescenteric amniotic membrane grafting in

keratoprosthesis-associated corneal melt. Arch Ophthalmol. 2010;128:779-82.

6. Dunlap K, Chak G, Aquavella JV, Myrowitz E, Akpek EK. Short-Term Visual

Outcomes of Boston Type 1 Keratoprosthesis Implantation. Ophthalmology

2010;117:687-92.

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7. Tzu JH, Desai NR, Akpek EK. Use of a microvascular clip for iris fixation of

an intraocular lens: a laboratory model. Arch Ophthalmol. 2010;128:114-6.

8. Akpek EK, Vittitow J, Verhoeven RS, et al. Ocular surface distribution and

pharmacokinetics of a novel ophthalmic 1% azithromycin formulation. J Ocul

Pharmacol Ther. 2009;25:433-9.

9. Ali FS, Akpek EK. Dry eye and glaucoma. Ophthalmology 2009;116:1232.

10. Akpek EK, Klimava A, Thorne JE, et al. Evaluation dry eye patients for

associated medical conditions. Cornea. 2009;28:493-7.

11. Gupta A, Sadeghi PB, Akpek EK. Occult thyroid eye disease in patients

presenting with dry eye symptoms. Am J Ophthalmol 2009;147:919-23.

12. Shan SJ, Wu EI, Akpek EK. Sterile corneal melt after descemet stripping

endothelial keratoplasty in patients with previously undiagnosed Sjogren

syndrome. Arch Ophthalmol 2009; 127: 219-20.

13. Adyanthaya RS, Folgar FA, Akpek EK. Medical management of acutely

recurring pterygium with topical mitomycin C. J Cataract Refract Surg

2009;35:200-2.

14. Jabs DA, Prendergast RA, Lee B, Akpek EK, et al. Autoimmune Th2-mediated

dacryoadenitis in MRL/MpJ mice becomes Th1-mediated in IL-4 deficient

MRL/MpJ mice. Invest Ophthalmol Vis Sci 2007;48:5624-9.

15. Coassin M, Zhang C, Green WR, Aquavella JA, Akpek EK. Histopathological

and immunohistochemical aspects of artificial corneal failure. Am J

Ophthalmol 2007;144:699-704.

16. Parekh P, Green WR, Stark WJ, Akpek EK. Electron microscopic investigation

of the lens capsule and conjunctival tissues in individuals with clinically

unilateral pseudoexfoliation syndrome. Ophthalmology 2007;114:

17. Akpek EK, Harissi-Dagher M, Petrarca R, Butrus SA, Pineda R, Aquavella JV,

Dohlman CH. Outcomes of boston keratoprosthesis in aniridia: a retrospective

multicenter study. Am J Ophthalmol, 2007;144:227-231.

18. Aquavella JV, Gearinger MD, Akpek EK, McCormick GJ. Pediatric

keratoprosthesis. Ophthalmology 2007;114:989-94.

19. Parekh P, Stark W, Green WR, Akpek EK. Subluxation of Suture-Fixated

Posterior Chamber Intraocular Lenses: A Clinicopathological Study.

Ophthalmology 2007;114:232-7

20. Pakravan M, Klesert T, Akpek EK. Conjunctival lichen planus. Br Journal

Ophthalmol, 2006;90:1325-6.

21. Bothelho PJ, Congon NG, Handa JT, Akpek EK. Keratoprosthesis in High-Risk

Pediatric Corneal Transplantation: First Two Cases. Arch Ophthalmol,

2006;124:1356-7.

22. Ilhan-Sarac O, Akpek EK. Current concepts and techniques in keratoprosthesis.

Curr Opin Ophthalmol 2005;16:246-50.

23. Tatlipinar S, Akpek EK. Topical Cyclosporin A in the Treatment of Ocular

Surface Diseases: An Evidence Based Review. Br J Ophthalmol

2005;89:1363-7.

24. Jabbur NS, Akpek EK, Stark WJ. Subluxation of iris-sutured intraocular lenses

and results of a closed chamber technique for repositioning. Cornea

2005;24:438-42.

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25. Jabs DA, Akpek EK. Immunosuppression for posterior uveitis. Retina

2005;25:1-18.

26. Akpek EK, Chan CC, Shen D, Green WR. Lack of herpetic viral etiology in the

choroidal tissues of a patient with serpiginous choroiditis. Ophthalmology

2004;111:2071-5.

27. Jabs DA, Gérard HC, Prendergast RA, Wang WY, Hudson AP, Akpek EK, et

al. Inflammatory mediators in autoimmune lacrimal gland disease in MRL/MPj

mice. Invest Ophthalmol Vis Sci 2004;45:2293-8.

28. Akpek EK, Watson S, Christen W, et al. A randomized, placebo-controlled trial

of topical cyclosporin 0.05% in steroid resistant atopic keratoconjunctivitis.

Ophthalmology 2004;111:476-82.

29. Akpek EK, Thorne JE, Qazi FA, et al. Evaluation of patients with scleritis for

systemic disease. Ophthalmology 2004;111:501-06.

30. Akpek EK, Jabs DA, Whittum-Hudson JA, et al. Chemokines in autoimmune

lacrimal gland disease in MRL/MPJ mice. Invest Ophthalmol Vis Sci,

2004;45:185-90.

31. Akpek EK, Gottsch JD. Ocular surface immune defense. Eye, 2003;17:949-56.

32. Akpek EK, Ilhan-Sarac O, Green WR. Topical cyclosporin in the treatment of

chronic sarcoidosis of the conjunctiva. Arch Ophthalmol 2003;121:1333-5.

33. Akpek EK, Ilhan-Sarac O. New treatments for serpiginous choroiditis.

Curr Opin Ophthalmol. 2003;14:128-31.

34. Akpek EK, Altan-Yaycioglu R, Karadayi K, et al. Long-term outcomes of

combined penetrating keratoplasty with iris sutured intraocular lens

implantation. Ophthalmology 2003;110:1017-22.

35. Akpek EK, Jabs DA, Tessler HH, Joondeph BA, Foster CS. Successful

treatment of serpiginous choroiditis with alkylating agents. Ophthalmology

2002;109:1506-13.

36. Akpek EK, Liu SH, Thompson R, Gottsch JD. Experimental helminthic

keratitis induced by paramyosin-calgranulin C (HuCOAg) complex. Invest

Ophthalmol Vis Sci 2002;43:2677-84.

37. Jun AS, Broman K, Van Do D, Akpek EK, Stark WJ, Gottsch JD. Endothelial

dystrophy, iris hypoplasia, congenital cataracts, and stromal thinning (EDICT)

syndrome maps to chromosome 15q15-q25. Am J Ophthalmol 2002;134:172-

6. 38. Akpek EK, Jun AS, Goodman DF, Green WR, Gottsch JD. Clinical and

ultrastructural features of a novel hereditary anterior segment dysgenesis.

Ophthalmology 2002;109:513-9.

39. Akpek EK, Baltatzis S, Yang J, Foster CS. Long-term immunosuppressive

treatment in serpiginous choroiditis. Ocul Immunol Inflamm 2001;9:153-68.

40. Akpek EK, Altan-Yaycioglu R, Stark WJ. Spontaneous corneal perforation in a

patient with unusual unilateral pellucid marginal degeneration. J Cataract

Refract Surg 2001;27:1698-1700.

41. Akpek G, Akpek EK, Lee S, et al. Unusual locations for lymphomas: case 3.

Successive occurrence of peripheral T-cell lymphoma with bilateral conjunctival

involvement in a patient with low-grade B-cell lymphoma. J Clin Oncol

2001;19:2964-6.

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42. Akpek EK, Liu SH, Gottsch JD. Induction of experimental autoimmune

keratitis by adoptive transfer of human corneal antigen-specific T cell line.

Invest Ophthalmol Vis Sci 2000; 41:4182-8. 43. Gottsch JD, Akpek EK. Topical cyclosporin stimulates neovascularization in

resolving sterile rheumatoid central corneal ulcers. Trans Am Ophthalmol Soc

2000;98:59-69.

44. Akpek EK, Gottsch JD. Herpes zoster sine herpete presenting with hyphema.

Ocul Immunol Inflamm 2000;8:115-8.

45. Akpek EK, Demetriades AM, Gottsch JD. Peripheral ulcerative keratitis

following clear corneal cataract extraction. J Cataract Refract Surg

2000;26:1424-7.

46. Nguyen QD, Uy HS, Akpek EK, Harper S, Zacks D, Foster CS. Choroidopathy

of systemic lupus erythematosus. Lupus 2000;9:288-98. 47. Akpek EK, Haddad RS, Winkelstein JA, Gottsch JD. Bilateral consecutive

central corneal perforations associated with hypogammaglobulinemia.

Ophthalmology 2000;107:123-6.

48. Akpek EK, Hasiripi H, Christen WG, Kalayci D. A randomized trial of low-

dose, topical mitomycin-C in the treatment of vernal keratoconjunctivitis.

Ophthalmology 2000;107:263-9.

49. Akpek EK, Maca SM, Foster CS. Elevated vitreous interleukin-10 level is not

diagnostic of intraocular-central nervous system lymphoma. Ophthalmology

1999;106:2291-5.

50. Sangwan W, Akpek EK, Zhao TZ, Pinar V, Yang J, Foster CS. Krill protease

effects on wound healing following corneal alkali-burn. Cornea 1999;18:707-

11.

51. Akpek EK, Ahmed I, Hochberg HF, Soheilian M, Dryja TP, Jakobiec FA,

Foster CS. Primary intraocular lymphoma: clinical features, diagnosis and

outcomes. Ophthalmology 1999;106:1805-10. (Selected to be included in the

Year Book of Ophthalmology, Wilson RP (ed), 2000;266-7.)

52. Akpek EK, Polcharoen W, Chan R, Foster CS. Ocular surface neoplasia

masquerading as chronic blepharoconjunctivitis. Cornea 1999;18:282-8.

53. Akpek EK, Polcharoen W, Ferry JA, Foster CS. Conjunctival lymphoma

masquerading as chronic conjunctivitis. Ophthalmology 1999;106:757-60.

54. Akpek EK, Uy H, Christine W, Gurdal C, Foster CS. Severity of episcleritis

and systemic disease association. Ophthalmology 1999;106:729-31.

55. Akpek EK, Kent C, Jakobiec FA, Caliendo AM, Foster CS. Bilateral acute

retinal necrosis caused by cytomegalovirus in an immunocompromised patient.

Am J Ophthalmol 1999;127:93-5.

56. Akpek EK, Ertoy D, Kalayci D, Hasiripi H. Post-operative topical mitomycin-C

in conjunctival squamous cell neoplasia. Cornea 1999;18:59-62.

57. Akpek EK, Merchant A, Pinar V, Foster CS. Ocular rosacea: patient

characteristics and follow-up. Ophthalmology 1997;104:1873-7. (Selected to

be included in the Year Book of Dermatology, Thiers BH, Lang PG (eds),

1998;155-7.)

58. Akpek EK, Ertoy D, Aslan Y, Recep OF, Hasiripi H. Invasive squamous cell

carcinoma of the conjunctiva: a case report. Ann Ophthalmol 1996;28:364-6.

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59. Kalaycı D, Bascı N, Akpek EK, Hasıripi H, Bozkurt A. Penetration of topical

0.3% ciprofloxacin into human aqueous humor. Ophthalmic Surg Lasers

1996;27:21-4.

In press:

60. Akpek EK, Lindsley K, Adyanthaya RS, Swamy R, Baer AN, McDonnell PJ.

Treatment of Sjögren’s syndrome-associated dry eye: An evidence-based

review. Ophthalmology.

Submitted:

61. Tzu JH, Utine CA, Stern M, Akpek EK. Topical cyclosporine 0.05% as a long-

Term monotherapy for atopic keratoconjunctivitis. Cornea

62. Utine CA, Tzu J, Akpek EK. Clinical features and outcomes of Boston type I

keratoprosthesis associated corneal melt. Acta.

63. Utine CA, Swamy R, Thorne JE, Baer AN, Akpek EK. Diagnosis of Sjogren’s

syndrome in patients presenting with dry eye. Ophthalmology.

64. Swamy R, Utine CA, Thorne JE, Baer AN, Akpek EK. Predictors of Sjogren’s

syndrome in patients presenting with dry eye. Ophthalmology.

65. Dokey A, Akpek EK. Chronic hypotony associated with Boston type 1

keratoprosthesis. Cornea.

66. Kpro aphakic vs pseudophakic Ophthalmology

Non-peer-reviewed articles:

1. Akpek EK. Evaluation of Patients With Dry Eye for Presence of Underlying Sjögren

Syndrome: author’s reply. Cornea. 2010 Jun 23.

2. Akpek EK, Kalayci D. Mitomycin-C and vernal conjunctivitis: authors’ reply.

Ophthalmology 2000;107:2126.

3. Akpek EK, Kalayci D. Mitomycin-C and vernal conjunctivitis: authors’ reply.

Ophthalmology 2000;107:2126-7.

4. Akpek EK, Foster CS. Elevated vitreous interleukin-10 level is not diagnostic of

intraocular-central nervous system lymphoma: authors’ reply. Ophthalmology

2001;108:426-7.

5. Foster CS, Akpek EK. Elevated vitreous interleukin-10 level is not diagnostic of

intraocular-central nervous system lymphoma: authors’ reply. Ophthalmology

2001;108:428.

6. Akpek EK, Foster CS. Primary intraocular lymphoma with a low interleukin 10 to

interleukin 6 ratio and heterogeneous IgH gene arrangement: letter to the editor. Arch

Ophthalmol 2000;118:731-2.

7. Akpek EK, Karadayi K. Ketorolac tromethamine 0.5% ophthalmic solution in the

treatment of moderate to severe ocular inflammation after cataract surgery: a

randomized, vehicle-controlled clinical trial: letter to the editor. Am J Ophthalmol

1999;128:662-3.

Book chapters:

1. Akpek EK, Gottsch JD. Mooren’s ulcer, in Current Ocular Therapy, 5th edition. Eds

Fraunfelder and Roy. WB Saunders Publishers, New York, 1999;367-9.

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2. Akpek EK, Foster CS. Limbal stem cell transplantation, in Surgical Advances in

Ophthalmology. Eds Jakobiec FA, Kryzstolic M. Lippincott, Williams and Wilkins,

Philadelphia, 1999; 39(1);71-82.

3. Akpek EK, Irkec M. Allergic conjunctivitis, in Cornea and External Disease: The

Essentials. Eds McDonnell P, O’Brien TP. Thieme Medical Publishers, Inc, New

York, in press.

4. Akpek EK, Altan-Yaycioglu R, Stark WJ. Six pearls in challenging corneal surgery,

in 101 Pearls in Cataract, Refractive and Corneal surgery. Eds. Melki SA, Azar DT.

Slack Incorporated, Thorofare, NJ, 2001;149-60.

5. Akpek EK, Altan-Yaycioglu R, Stark WJ. Corneal stability and biomechanics after

LASIK, in LASIK. Eds Azar DT, Koch DD. Marcel Dekker, Inc, New York,

2002;163-72.

6. Akpek EK, Ilhan-Sarac O. Cicatrizing conjunctivitis, in Smolin and Thoft’s The

Cornea, 4th edition. Eds Foster CS, Azar DT, Dohlman C. Lippincott Williams and

Wilkins, Philadelphia.

7. Akpek EK, Jabbur NS, Daines BS, Stark WJ. Corneal ectasia after LASIK, in

Myopia and Related Diseases: A Clinical and Therapeutic Approach. Midena E. Ed.

Fondazione G.B. Bietti per lo Studio e la Ricerca in Oftalmologia ONLUS,

Ophthalmic Communications Society, Inc., New York, 2005; 443-448.

8. Daines BS, Akpek EK, Jabbur NS, Stark WJ. Update on phakic intraocular lenses, in

Myopia and Related Diseases: A Clinical and Therapeutic Approach. Midena E. Ed.

Fondazione G.B. Bietti per lo Studio e la Ricerca in Oftalmologia ONLUS

Ophthalmic Communications Society, Inc., New York, 2005; 453-459.

9. Sen N, Eser I, Akpek EK. Lamellar keratoplasty in perforated pellucid marginal

degeneration. Section V: Tectonic lamellar keratoplasty. In: Surgical Techniques in

anterior and posterior lamellar corneal surgery. Ed: Thomas John. Jaypee Brothers

Medical Publishers (P) LTD, New Delhi, 2005;469-476.

10. Jabs DA, Akpek EK. Immunosuppressive therapy for posterior segment disease.

Retina, 4th edition. Editor in Chief: Stephen Ryan. Elsevier, London, 2005.

11. Suh L, Akpek EK, Stark WJ. Tectonic lamellar keratoplasty in Mooren’s and

Mooren’s-like corneal ulcers. Section V: Tectonic lamellar keratoplasty. In: Surgical

Techniques in anterior and posterior lamellar corneal surgery. Ed: Thomas John.

Jaypee Brothers Medical Publishers (P) LTD, New Delhi, 2005;483-490.

12. Tatlipinar S, Akpek EK. Scleritis. In: Current Ocular therapy 6th edition. Eds: F

Hampton Roy, Frederick T Fraunfelder, Frederick W Fraunfelder. Elsevier. Chapter

347, pp 653-656.

13. Lekhanont K, Panday V, Akpek EK. Permanent Keratoprostheses. Part V, Special

Situations in Corneal Surgery. In: Corneal Surgery, Theory, Technique and Tissue 4th

edition. Eds: F Brightbill, P J McDonnell, C N J McGhee. Assoc Ed: A A Farjo.

Elsevier. China, 2009. Chapter 78, pp 683-690.

14. Marangoz D, Akpek EK. Behcet Hastaligi. Uveit Kitabi. Akduman L and Aydin P,

eds. Gunes Tip Kitap Evleri, pages 171-182, Ankara, 2007.

15. Suh L, Akpek EK. Corneal Gluing. In: Basic Techniques of Ophthalmic Surgery.

Eds: JP. Dunn, PD. Langer. American Academy of Ophthalmology. San Francisco,

2009. Chapter 5, pp 34-37.

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16. Srikumaran D, Tzu JH, Akpek EK. Cicatrizing Conjunctivitis. Focal

Points, Clinical Modules for Ophthalmologists. San Francisco, CA:

American Academy of Ophthalmology. 2010:29(1):1-9.

17. Dokey A, Akpek EK. "Aqueous tear deficiency and Sjogren´s syndrome". Atlas

and Text of Corneal Pathology and Surgery, English Edition. Eds: S Boyd, AM

Gutierrez, JP McCulley editors. Jaypee Highlights Medical Publishers, 2011, 7:81-92.

18. Gupta A, Akpek EK. What are the indications and contraindications for the use of

periocular corticosteroid injections? Curbside uveitis.

19.

Other media:

1. Akpek EK. Behcet’s Disease: an overview. Ocular Immunology website,

www.immunology.meei.harvard.edu. January 1997.

2. Akpek EK. Peripheral ulcerative keratitis associated with acne rosacea. Ocular

Immunology website, www.immunology.meei.harvard.edu. March 1997.

3. Akpek EK. Necrotizing scleritis: diagnosis and therapy. Ocular Immunology

website, www.immunology.meei.harvard.edu. November 1996.

4. Akpek EK. Allergic conjunctivitis. Ocular Immunology website,

www.immunology.meei.harvard.edu. May 1998.

5. Akpek EK. Conjunctival sebaceous cell carcinoma masquerading as chronic

conjunctivitis. Ocular Immunology website, www.immunology.meei.harvard.edu.

June 1998.

6. Akpek EK, Gottsch JD. Basic Immunology. www.yourdoctor.com.

7. Akpek EK, Weinberg R. Behcet’s disease, Patient Monograph. American Uveitis

Society website, www.aus.org

8. Altan-Yaycioglu R, Akpek EK, Stark WJ: Improvement of Corneal Opacity in

Peters' Anomaly . The Internet Journal of Ophthalmology and Visual Science. 2004.

Volume 3 Number 1.

http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijovs/vol3n1/peter.xml

9. Wu I, Akpek EK. Blepharitis.

https://online.epocrates.com/u/2911574/Blepharitis/Summary/Highlights

Extramural Sponsorship:

Grants:

1999-2002 Unrestricted clinical research grant from Allergan, Inc; Co-

Principal Investigator (75% effort); “Topical Cyclosporin in

the Treatment of Anterior Segment Inflammatory Diseases”

(total cost $142,400)

2004 Research to Prevent Blindness, William and Mary Greve

special scholar, for “Immunopathology of Atopic

Keratoconjunctivitis” ($ 60,000)

2004-2011 Principal Investigator (20% effort); “Effects of Topical

Cyclosporin Therapy in the Immunopathology of Atopic

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Keratoconjunctivitis” from Allergan, Inc., ($90,000/ current

year, total direct cost $422,000)

2004 Director’s Discovery Fund, The Wilmer Eye Institute,

Principle Investigator (1% effort) “Keratoprosthesis in

Children with Congenital Anterior Segment Anomalies” ($

10,000)

2006-2007 Principle Investigator; Keratoprosthesis, from WL Gore

Assoc., ($78,000) (40% effort)

2009 Principal Investigator (1% effort) “A Phase I/II Prospective,

Randomized, Double Masked, Vehicle And Comparator

Controlled, Dose Ranging Study Of Cp-690,550 In Subjects

With Dry Eye Disease” ($78,117), sponsored by Pfizer Inc.

2009 Principal Investigator (1% effort) “A Multi-Center,

Prospective, Observational Study of the Progression of

Ocular Findings in Patients with Dry Eye Disease” ($78,

330), sponsored by Allergan Inc.

2009 Principal Investigator (1% effort) “A Randomized, Multi-

Center, Double-Masked, Placebo-Controlled, Parallel-Group

Safety and Efficacy Study of Azithromycin Ophthalmic

Solution 1% versus Placebo for Two Weeks in Subjects with

Blepharitis” ($42,300), sponsored by Inspire

Pharmaceuticals, Inc. (National Chair of the Study

Committee)

2009 Principal Investigator (1% effort) “A Multi-Center,

Randomized, Double-Masked, Parallel-Group Study

Evaluating the Efficacy and Safety of Cyclosporin

Ophthalmic Solution 0.010% Compared with Its Vehicle

Administered QID for 3 Months Followed by a 9 Month

Open-Label Phase in Patients with Atopic

Keratoconjunctivitis” ($117, 046), sponsored by Allergan

Inc. (National Chair of the Study Committee)

2009-2013 Co-Principle Investigator (10% effort) “International

Sjogren's Syndrome Registry”, (total cost $825,352),

sponsored by NIH

EDUCATIONAL ACTIVITIES

Teaching:

Classroom instruction:

1996-1998 Corneal Wound Healing, Immunology Seminars (one-hour

lecture, given once a year to the basic scientists and

students), Massachusetts Eye and Ear Infirmary, Harvard

Medical School.

1996-1998 Clinical Immunology Series (five half-hour lectures)

Massachusetts Eye and Ear Infirmary, Harvard Medical

School, (see www.uveitis.org for the titles and texts).

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2002-2004 Eye and Systemic Disease (one-hour lecture); part of one-

week required clerkship for Johns Hopkins medical students.

2002-2005 Clinicopathologic Correlations (two-hour review on

conjunctivitis, keratitis, sarcoid and angle closure glaucoma),

Eye section of the Year 2 curriculum, Johns Hopkins medical

students.

2003-2010 Cataract, Refractive Surgery and Red Eye (Year 2 and 3

Johns Hopkins Medical Students)

2003-present Residency core lectures (four one-hour lectures per year):

Immune-Mediated Disorders of the Eyelid & Conjunctiva,

Ocular Surface Disorders: Dermatoses, Structural &

Exogenous Disorders, Ocular Surface Disorders: Dry Eye,

Nutritional & Physiologic Disorders, Ocular Herpetic

Infections for Wilmer Eye Institute resident

ophthalmologists.

2006-present Cornea, Cataract, External Diseases, Refractive Surgery Bi-

Monthly Journal Clubs (for Wilmer Eye Institute residents as

well as Cornea Fellows)

2007-2009 Ocular Allergy (one hour lecture as part of required

classroom lecture series for Allergy Immunology Clinical

Fellows at Bayview Allergy Immunology Center)

Clinical instruction:

2002-present Clinical preceptorship (eight half-days per year), part of the

required one-week clerkship of 3rd and 4th year Johns

Hopkins medical students.

2002-present Clinical skills sessions (two-hour hands-on course on

ophthalmology examination techniques), 2nd year Johns

Hopkins medical student education.

2004-present Clinical Patient Practicum. A two hour practical course on

ophthalmology examination techniques, part of required

Ophthalmology Clerkship curriculum, 3rd

and 4th year Johns

Hopkins medical student education.

2002-present Clinical preceptorship (one full day per week at the Wilmer

Eye Institute, Johns Hopkins Medical School), 2nd year

ophthalmology residents.

2002-present Surgical preceptorship (one full day per week with second

year residents, and two full days per month with the 3rd year

ophthalmology residents), Wilmer Eye Institute, Johns

Hopkins Medical School.

2002-present Surgical and clinical preceptorship, as part of Cornea and

External Diseases Fellowship Program (One full day per

week in the operating room and one full day per week in the

clinic).

Research instruction:

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2002-present Research preceptorship, “Clinical/basic research in cornea

and external eye disease,” a six-week medical student

elective, for Johns Hopkins medical students and foreign

medical students (typically one or two medical students

during the spring-summer).

2000-present Research preceptorship (research related to allergic and

immunologic ocular surface diseases), postdoctoral Fellows,

mainly from outside the USA (typically one or two fellows

per year).

CME instruction:

2000 Course Instructor, Cornea Day, Wilmer Eye Institute,

Baltimore, Maryland

2000-2006 Course Instructor, annual Wilmer Ophthalmological Institute

Clinical Meeting, Baltimore, Maryland.

2001-present Course Instructor in annual “Current Concepts in

Ophthalmology” course, Baltimore, Maryland.

2002-2007 Course Instructor in annual “Ophthalmology for the Medical

Practitioner”, Baltimore, Maryland.

2002-present Course Instructor, International Ocular Inflammation Society

Meeting, held every other year in various European

countries.

2003-present Course Instructor in Biannual Uveitis 2003 Subspecialty

Day, in conjunction with the American Academy of

Ophthalmology.

2004-2009 Participant in International Ocular Inflammation Society

Continuous Medical Education Program.

2005-present Course Instructor (with Dr. Parekh), Joint Commission on

Allied Health Personnel in Ophthalmology, in conjunction

with the annual American Academy of Ophthalmology.

Infiltrates and inflammatory ulcers of the cornea (05SA5)

2007 Course Instructor, “Managing Concomitant Eye Diseases: An

Experts’ View on Glaucoma and Dry Eye” Epidemiology of

Dry Eye and Glaucoma, November, 2007

2006-present Course Instructor, Wilmer Annual Ophthalmic Technician

Course, “Herpetic Keratoconjunctivitis”.

2008-present Course Instructor, “The Boston Keratoprosthesis: What You

Don’t Know Will Surprise You”, at the Annual Academy of

Ophthalmology Meeting

2008-present Course Instructor, Wilmer Annual Ophthalmic Nurses

Course, “Dry Eye Syndrome”.

Mentoring (Advisees):

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2002-2003 Ozge Ilhan-Sarac, MD, former research fellow and currently

an academician ophthalmologist in Ankara, Turkey. Awarded

Turkish Scientific Council Clinician Scientist Scholarship for

“Keratoprothesis; Artificial Cornea” project.

2003-2004 John Kim, MD. Currently employed as the “Ophthalmology

Residency Program Director” at Albert Einstein Medical

Center.

2000-present Hatice Nida Sen, MD. Former medical student at the

Hacettepe University School of Medicine, Ankara-Turkey.

Currently The Fellowship Director of the Uveitis Clinical and

Research Fellowship at the National Institutes of Health.

2000-2001 Rana Altan-Yaycioglu, former Research and Clinical Fellow.

Currently an Associate Professor in Ophthalmology, Baskent

University, Adana-Turkey

2002-2002 Ama Doubrofi, Medical Student from Ghana, went into

ophthalmology residency in Ghana.

2003-2003 Justin Anderson, Medical Student in Texas, went into

ophthalmology residency at New York Eye and Ear

Infirmary, New York. Currently in private practice in TX.

2003 Dong Choe, Undergrad student. Johns Hopkins University.

2004-present Carly Benner, Undergrad student. Johns Hopkins University.

Accepted to Harvard Medical School.

2004-present Parag Parekh, MD, Resident at The Wilmer Eye Institute,

2005- A. E. Maumenee Reseach Grant Award for

“Subluxation of Suture Fixated Intraocular Lenses”

2007-Mitchell Prize 3rd

place.

2006- Richard Green Research Grant Award for “Unilateral

Pseudoexfoliation”. Both papers are in print.

2005-2006 Paul Botelho, Postdoctoral Fellow. Published “Botelho PJ,

Congdon NG, Handa JT, Akpek EK. Kertatoprosthesis in high-risk

pediatric corneal transplantation: first 2 cases. Arch Ophthalmol.

2006 Sep;124(9):1356-7”

2006-present Anita Gupta, Resident at The Wilmer Eye Institute, 2007

2007-Julia Haller Research Award for “Occult Thyroid Eye

Disease in Patients Presenting with Dry Eye Symptoms”.

Paper is in print.

2005-present Alena Klimava, Medical student, Johns Hopkins University

Currently a resident in ophthalmology, UCSF. Published

“Akpek EK, Klimava A, Thorne JE, et al. Evaluation dry eye

patients for associated medical conditions. Cornea.

2009;28:493-7.”

2006-2007 Marco Coassin, postdoctoral fellow. Worked on etiology of

artificial cornea failure. Published “Coassin M, Zhang C, Green WR, Aquavella JV, Akpek EK. Histopathologic and immunologic

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aspects of aplhacor corneal failure. Am J Ophthalmol. 2007

Nov;144(5):699-704

2008-2010 Rohit Adyanthaya, Postdoctoral Fellow. Published Medical

management of acutely recurring pterygium with topical

mitomycin-C.

2008-present Shannon Shan, Medical Student, Johns Hopkins University

Published “Shan SJ, Wu EI, Akpek EK. Sterile corneal melt

after descemet stripping endothelial keratoplasty in patients

with previously undiagnosed Sjogren syndrome. Arch

Ophthalmol 2009; 127: 219-20.” Will be a resident at

Wilmer Eye Institute in July 2011.

2008-present Jonathan Tzu, Medical Student, Johns Hopkins University.

Currently a resident in ophthalmology at Bascom Palmer Eye

Institute. Worked on establishing a database for all patients

who underwent an artificial and donor corneal trnaplantation.

Published multiple papers, and also more are in press, see

CV.

2009-2010 Canan Asli Utine, MD, Assistant Professor of

Ophthalmology, Yeditepe University Eye Hospital, Istanbul,

Turkey. Published multiple papers and more are in press

currently. She is now in the process of being promoted to

Associate Professor at her institution.

2009-present Ferhina Ali, Medical Student, Johns Hopkins University.

Published “Ali FS, Akpek EK.Glaucoma and dry eye. Ophthalmology. 2009 Jun;116(6):1232.”

2010 Evelyn Tay, Medical Student, Singapore. Published “Tay E, Utine

CA, Akpek EK. Cresenteric amniotic membrane grafting in keratoporsthesis-assoicated Corneal Melt. Arch Ophthalmol. 2010

Jun;128(6):779-82.”

2009-present Ramya Swamy, MD, Medical Student, Johns Hopkins

University. Worked on Sjogren’s Syndrome related dry eye

trials. Has several papers in press, see CV. Will be an

ophthalmology resident at Doheny Eye Institute, CA in July

2011.

2010-present Adrian Dokey, BS, currently Medical Student, Johns

Hopkins University. Worked on establishing a database for

all dry eye patients with Sjogren’s Syndrome. Several papers

as well as a book chapter are in press currently, see CV. Will

be an ophthalmology resident at Wilmer in July 2012.

Editorial Activities:

1998-present Scientific Reviewers’ Board, Ophthalmology

2001-present Ad Hoc Reviewer, Archives of Ophthalmology

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2001-present Ad Hoc Reviewer, British Journal of Ophthalmology

2003-present Ad Hoc Reviewer, Current Eye Research

2003-present Ad Hoc Reviewer, American Journal of Ophthalmology

2003-present Ad Hoc Reviewer, Ophthalmic Epidemiology

2003-present Ad Hoc Reviewer, BMC Ophthalmology

2003-present Ad Hoc Reviewer, Investigative Ophthalmology and

Visual Sciences

2003-present Ad Hoc Reviewer, Progress in Retinal and Eye Research

2004-present Ad Hoc Reviewer, Journal of Ocular Inflammation and

Immunology

2004-present Ad Hoc Reviewer, Cornea

2005-present Editorial Board Member, Current Drug Therapy

2006-present Ad Hoc Reviewer, New England Journal of Medicine

2006-present Ad Hoc Reviewer, Neuro-ophthalmology

2007-present Editorial Board Member, Contemporary Ophthalmology

2007-present Ad Hoc Reviewer, Drugs & Aging Journal

2008-present Editorial Board Member, Advances in Therapy

2009-present Editorial Board Member, Turkiye Klinikleri Dergisi

2009-present Reviewing Editor, Journal Ocular Immunology and

Inflammation

2009-present Editorial Board Member, Journal of European Medical

Students Association

2009-present Editorial Board Member, Advanced Ocular Care

2010-present Editorial Board Member, Marmara Medical Journal

CLINICAL ACTIVITIES

Certification:

1991-present Medical License, Turkey (91AB064)

1995-present Diplomat of the Turkish Board of Ophthalmology

1997-present Visex PRK-PTK Certificate

1998-present Chiron Vision LASIK Certification

2002-present Medical License, Maryland (00D58519)

2003-present ArgusConnect (Alphacorkeratoprosthesis) Accreditation

Certificate

Service Responsibilities:

Holds clinics, two full days per week, at the Cornea Service of the Wilmer Eye Institute.

One day per week is devoted to the “Ocular Surface Diseases and Dry Eye Clinic” where

patients with allergic and immunologic diseases of the ocular surface (scleritis, keratitis,

cicatrizing conjunctivitis, dry eye and ocular surface diseases associated with

autoimmune and collagen vascular disorders) are managed. Dr. Akpek is the Director of

the Ocular Surface Clinic. The other day id devoted to surgical patients. Dr. Akpek

performs various surgeries, one day per week, to reconstruct the ocular surface in patients

with destructive anterior segment problems including lamellar and penetrating

keratoplasty, amniotic membrane and scleral grafting, limbal stem cell transplantation

15

and artificial cornea surgery. Dr. Akpek is the only faculty member who performs

artificial corneal surgeries. Dr. Akpek receives numerous patient referrals from within as

well as outside the United States who need these surgeries.

Dr. Akpek spends two days per week doing laboratory and clinical research as well as

teaching.

Dr. Akpek also participates in the Sjogren’s Syndrome Center at the Bayview Medical

Center and holds clinics one day per month. Dr. Akpek is the Associate Director of the

Center.

ORGANIZATIONAL ACTIVITIES

Professional Societies:

1996-present American Academy of Ophthalmology

1997-2009 Turkish-American Ophthalmologic Society

1996-1999 American Society of Cataract and Refractive Surgery

1996-1999 Contact Lens Association of Ophthalmologists

1997-2000 Massachusetts Medical Society

1997-present Association for Research in Vision and Ophthalmology

1997-2000 American Medical Association

1997-present International Ocular Inflammation Society

1998-present The Cornea Society (formerly Castroviejo Society)

1998-present American Uveitis Society

2001-2005 Pan American Association of Ophthalmology

2003- present International Society of Dacryology and Dry Eye

2003-present Tear Film and Ocular Surface Society

2006- present Keratoprosthesis Study Group

2006-2009 President, Turkish American Ophthalmological Society

Session Chair:

2000 Moderator; session title “Genetics,” 3rd International

Conference on Cornea, Eye Banking and External

Diseases, International Federation of Eye Banks, Istanbul,

Turkey, July 2000.

2003 Moderator; session title “Regulatory Mechanisms of Ocular

Surface Inflammation,” ARVO, Fort Lauderdale, FL, May

2003.

2004 Moderator, session title “Advances in Keratoplasty”,

AfroAsian Ophthalmological Meeting, Istanbul, Turkey

2004.

2004 Co-Moderator, session title “Paper Presentations in

Anterior Segment Diseases ”, AfroAsian Ophthalmological

Meeting, Istanbul, Turkey 2004.

2007 Session Chair; poster session on tear film. 5th International

Conference on the Tear Film and Ocular Surface: Basic

Science and Clinical Relevance. September, 2007, Italy.

2006-present Chair, Ocular Surface Diseases and Dry Eye Grandrounds,

held in the month of May every year, Baltimore, Maryland.

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2010 Moderator, session title “Ocular Surface Disease: Clinical

Aspects”, International Ocular Surface Society Meeting,

Fort Lauderdale, May 1, 2010

2010 Session Chair; Sjogrens’ Syndrome. 6th International

Conference on the Tear Film & Ocular Surface: Basic

Science and Clinical Relevance. Florence, Italy

Consultantship:

2005-2006 Consultant’s Agreement, W. L. Gore & Associates, Inc.,

“Keratoprosthesis: Artificial Cornea.”

2007-2010 Consultant’s Agreement, Lux Biosciences, “Voclosporin

Treatment of Sjogren’s Syndrome Associated Dry Eye”.

2008-present Consultant’s Agreement, Pfizer, Topical

Immunosuppression in the Treatment of Dry Eye

Syndrome”.

Patents:

2008 Novel Keratoprosthesis. Co-Inventor. US Patent

Application No. 2008/0255,663. Title: Artificial Cornea

and Method of Making Same.

Administrative Responsibilities

2003-2006 Delegate, Uveitis Self Assessment Committee, American

Academy of Ophthalmology.

2003-2008 Wilmer Eye Institute, Cornea and External Diseases

Fellowship program description and curricular activities

(created and responsible for updating as needed) and

Fellows’ Advocate

2004-2010 Co-Director, Ophthalmology Clerkship Program, Johns

Hopkins Medical School

2005 Mind/Brain Content Committee, Johns Hopkins University,

Medical School

2005-present Member, Mitchell Prize Committee, a selection committee to

fund outstanding Wilmer resident research

2005-present Associate Professor Promotion Committee, The Wilmer Eye

Institute, Johns Hopkins Medical School

2005-present Clinical Practice Association Committee, The Wilmer Eye

Institute.

2007-2009 President, Turkish-American Ophthalmologists Society.

2009-present Member of Medical & Scientific Advisory Board, Tear Film

& Ocular Surface Society

2010-present Director, Cornea and External Disease Clinical Fellowship

Program, The Wilmer Eye Institute, Johns Hopkins

University Medical School.

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2010-present Representative, Medical School Council, Johns Hopkins

University School of Medicine.

RECOGNITION

Honors and Awards:

1998 Immunology Award, Ocular Immunology and Uveitis

Service, Massachusetts Eye and Ear Infirmary, Harvard

Medical School

2000 Cora Verhagen Immunology Prize, Association for

Research in Vision and Ophthalmology 2000, Fort

Lauderdale, FL, for “Induction of Peripheral Ulcerative

Keratitis by Adoptive Transfer of Human Corneal Antigen-

Synthesized T Lymphocytes”

2001 Honored by Turkish-American Ophthalmologists Society,

November 2001, New Orleans

2003 Recipient of “Daughters of Ataturk Award”, for

outstanding international Turkish woman.

2004 Achievement Award, America Academy of

Ophthalmology.

2004 Selected to be included in “Guide to America’s Top

Ophthalmologists” by Consumers’ Research Council of

America.

2005 Resident Advocate Award, The Wilmer Eye Institute

Residency Training Program

2007 Selected to be included in “Guide to America’s Top

Ophthalmologists” by Consumers’ Research Council of

America.

2008 Neil R. Miller Full Time Faculty Medical Student Teaching

Award, Johns Hopkins Medical School.

2009 Selected to be included in “Best Doctors in America” by

Consumers’ Research Council of America.

2010 Selected to be included in “Best Doctors in America” by

Consumers’ Research Council of America.

Invited Talks:

1. Foster CS, Akpek EK. Episcleritis and Scleritis Course. Presented by invitation at

the XIth European Society of Ophthalmology Meeting, Budapest, Hungary, June

1997.

2. Akpek EK. Scleritis-Episcleritis-Uveitis Course. Presented by invitation at the

Annual Meeting of American Society of Ophthalmic Registered Nurses, in

association with 102nd American Academy of Ophthalmology Meeting, New

Orleans, November 1998.

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3. Akpek EK, Foster CS. Limbal stem cell transplantation. Presented by invitation at

the Annual Fellows’ Course of Massachusetts Eye and Ear Infirmary, Harvard

Medical School, “Surgical Advances in Ophthalmology,” Boston, February 1998.

4. Akpek EK. Ocular surface malignancies presenting as chronic conjunctivitis:

sasquerade syndrome. Presented by invitation at the Cornea Day, The Wilmer Eye

Institute, Johns Hopkins Hospital, Baltimore, January 1999.

5. Akpek EK. Corneal gene expression and graft rejection. Presented by invitation at

the session entitled “Genetics,” 3rd International Conference on Cornea, Eye

Banking and External Diseases, International Federation of Eye Banks, Istanbul,

Turkey, July 2000.

6. Akpek EK. Refractive surgery marketing. Presented by invitation at the Current

Concepts in Ophthalmology, Baltimore, December 2000.

7. Akpek EK. Therapeutic algorithm for herpes virus keratitis. Presented by invitation

at the session entitled “Advances in Ocular Infectious Diseases Symposium,” XIII

Congress of the European Society of Ophthalmology, Istanbul, Turkey, June 2001.

8. Akpek EK. Biology of limbal stem cells and therapeutic applications. Presented by

invitation at the session entitled “Ocular Surface Disease and Its Management,” XIII

Congress of the European Society of Ophthalmology, Istanbul, Turkey, June 2001.

9. Akpek EK. Scleritis and systemic disease association. Presented by invitation as a

“Keynote Lecture” at the Turkish-American Ophthalmologists Society Meeting in

conjunction with American Academy of Ophthalmology Meeting, New Orleans,

November 2001.

10. Akpek EK. Clinical uses of topical cyclosporin A. Presented by invitation at the

session entitled “Cyclosporin,” 7th Congress of the International Ocular

Inflammation Society, Padua, Italy, May 2003.

11. Akpek EK. Keratoprosthesis: Patient Selection, Surgical Technique and Outcomes”,

AfroAsian Ophthalmology Meeting, Istanbul Turkey, June 2004.

12. Akpek EK. Masquarede syndromes: Tis or Thisn’t. Second Update on Ocular

Infectious Disease. May 21-22, 2004. Johns Hopkins Hospital, Baltimore, Maryland.

13. Akpek EK. Scleritis and systemic disease association. Georgetown University

Grand Rounds, November 2004, Washington DC.

14. Akpek EK. Serpiginous choroiditis and Multifocal Choroiditis: An Evidence-Based

Review of Treatment, Uveitis Symposium, Annual American Academy of

Ophthalmology Meeting, New Orleans, 2004.

15. Akpek EK. Stevens Johnson Syndrome and Graft versus Host Disease. Uveitis

Subspecialty Day, Annual American Academy of Ophthalmology Meeting, Chicago,

2005.

16. Akpek EK. “Update in cornea and external disease.” Women in Ophthalmology

Annual Retreat, Aspen, CO, July 2005.

17. Akpek EK. Ocular Surface Disease. A 2-hour course. Optometric Continuing

Education Program, Maryland Optometric Association, June 5, 2005, Baltimore,

MD.

18. Akpek EK. Cataract surgery in uveitis patients. TOD-AAO Panel at the TOD 39th

Annual National Ophthalmology Congress, September 2005 Turkey.

19

19. Roh M, Akpek EK. Basic ophthalmological examination. TOD-AAO Basic Skills

Course at the TOD 39th

Annual National Ophthalmology Congress, September 2005,

Antalya, Turkey.

20. Akpek EK. Keratoprosthesis for pediatric cases. 6th KPro Study Group Meeting,

Miami, Florida, May 2006.

21. Akpek EK. Current concepts on dry eye diagnosis and treatment. Maryland Society

of Eye Physicians and Surgeons. October 13, 2006, Baltimore, MD.

22. Akpek EK. Keratoprosthesis in High Risk Corneal Transplantation Patients.

Advances in Anterior Segment Surgery. Sponsored by U.S. Army Medical

Command, hosted by Walter Reed Army Medical Center, Uniformed Services

University of the Health Sciences. March, 2007, Bethesda, MD.

23. Akpek EK. Management and Update of Dry Eye Inflammation. Current Concepts in

Ophthalmology, A Forum for Global Ophthalmic Innovators Meeting, Cataract

Surgery-Cornea Session, April, 2007, Baltimore, MD.

24. Akpek EK. New Approaches to Ocular Surface Diseases. Advances in

Ophthalmology. Maryland Society of Eye Physicians and Surgeons, 2007 Annual

Scientific Assembly, May 2007, Baltimore, MD.

25. Akpek EK. Keratoprosthesis: History, Patient Selection, Techniques and Results.

Advances in Ophthalmology. Maryland Society of Eye Physicians and Surgeons

2007 Program for Ophthalmic Medical Personnel May 2007, Baltimore, MD.

26. Akpek EK. Dry eye and systemic disease association. 5th

International Conference

on the Tear Film and Ocular Surface: Basic Science and Clinical Relevance, Italy

September 2007.

27. Akpek EK. Dry eye syndrome and systemic disease association. Visiting

Professorship, University of Rochester Eye Institute, August, 2006.

28. Akpek EK. Keratoprosthesis: Current Techniques and Future Developments.

Visiting Professorship, Massachusetts Eye Research and Surgery Institution,

November 2007.

29. Akpek EK. Cataract Surgery in Patients with Uveitis. 23rd

Biennial Walter Reed

Ophthalmology Postgraduate Course and Alumni Meeting. Bethesda, Maryland,

March 2008.

30. Akpek EK. 25th

Annual Wilmer Nursing Conference, Baltimore, MD, May 2008,

Changing Patterns of Contact Lens Related Infections.

31. Akpek EK. Tidewater Ophthalmology and Otolaryngology Meeting, Virginia

Beach, May 2008. Dry Eye Syndrome: Any Relief in Sight?

32. Akpek EK. Keynote Speaker, Oculoplastics Session, Virginia Society of

Ophthalmology Meeting, Washington, DC, June 2008. Masquarede Syndromes: This

or Thisn’t.

33. Akpek EK. Combined penetrating keratoplasty with sutured intraocular lens

implantation. World Ophthalmology Congress, Hong Kong June 2008.

34. Akpek EK. Combined penetrating keratoplasty with sutured intraocular lens

implantation. RANZCO, Sidney, Australia, November 2008.

35. Akpek EK. Visiting Professor, Cornell-Weil University Medical School,

Department of Ophthalmology, “Dry Eye and Systemic Disease Association”, New

York, June, 2009.

20

36. Akpek EK. Invited Speaker, Systemic Diseases Session, “Dry Eye and Systemic

Disease Association”, IOIS, Prague, Check Republic, June 2009.

37. Akpek EK. Invited Speaker, Diseases of the Anterior Segment Session, “Maquarede

Syndromes: This or Thisn’t”, IOIS, Prague, Check Republic, June 2009.

38. Akpek EK. Visiting Professor, Diseases of the Ocular Surface Session, “Refractory

Dry Eye”, Yale Cornea Cataract Symposium, New Heaven, CT, October 2009

39. Akpek EK. Visiting Professor. New York Eye and Ear, “Keratoproshesis: History,

Current Techniques and Future Devices” November 2009.

40. Akpek EK. Visiting Professor. 55th Annual Rochester Ophthalmology Conference.

Dry Eye and Systemic Disease Association. March 2010.

41. Akpek EK. Predictors of Sjogren’s syndrome in patients with dry eye. 6th

International Conference on the Tear Film and Ocular Surface: Basic Science and

Clinical Relevance, Italy September 2007.

42. Akpek EK. Tear Film & Ocular Surface Society: A Report from the International

Workshop on Meibomian Gland Dysfunction. European Association for Vision and

Eye Research, Crete, Greece, October 2010.

43. Akpek EK. What lies ahead – Single Piece Keratoprosthesis. 25th

APAO, Beijing,

China, September 2010.

44. Akpek EK. Visiting Professor. George Washington University, “Keratoprosthesis:

Future Considerations” September 2010.

Invited Reviews, Editorials:

1- Akpek EK, Ilhan-Sarac O. New treatments in serpiginous choroiditis. Curr Opin

Ophthalmol, 2003 ;14:128-31.

2- Ilhan-Sarac O, Akpek EK. Atopic keratoconjunctivitis: Current Thinking and

Treatment, International Ocular Inflammation and Immunology Society Newsletter,

summer 2004.

3- Ilhan-Sarac O, Akpek EK. Current concepts and techniques in keratoprosthesis. Curr

Opin Ophthalmol 2005;16:246-50.

4- Suh LH, Akpek EK. Stevens Johnson Syndrome. International Ocular

Inflammation and Immunology Society Newsletter, summer 2005.

6- Reznik J, Kim A, Dekhayser J, Akpek EK. Gatifloxacin 0.3% Ophthalmic Solution in

the Treatment of Bacterial Keratitis. Expert Rev Ophthalmol 2008;3:21-7.

7- Akpek EK. Dry Eye on the Rise. Editorial. Eyeworld, 2007.

8- Lekhanont K, Srikumaran D, Akpek EK. Pediatric keratoplasty. Expert Rev

Ophthalmol 2008;3:655-663.

9- Akpek EK. The Art Behind the Science of Dry-Eye Detection. Editorial. Rev

Ophthalmol November 2008.

10- Akpek EK, Barber LG, Perry HD, Pflugfelder SC, Wilson SE. Is there a dry eye in

the house? A science Writer’s Guide to Dry Eye. Sponsored by American Academy of

Ophthalmology, 2006.

11- McDonald MB, Akpek EK, Karpecki P, Pflugfelder SC. The VIEW II: Halting

Progression of Dry Eye Disease. SynerMed® Communications Proceedings

TM

Newsletter. June 2009.

13- Utine CA, Akpek EK. What ophthalmologists should know about Sjögren’s

syndrome. European Ophthalmic Review vol 4, 2010;1-6.

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14- Utine CA, Stern M, Akpek EK. Clinical Review: Topical Ophthalmic Use of

Cyclosporin A. Ocul Immunol Inflamm. 2010 Aug 25.

Other educational activities

2010 Member, the Uveitis section of the Practicing Ophthalmologists

Curriculum, for the MOC Exam Study Kit. American Academy of

Ophthalmology, as representative of the American Uveitis Society

2010 Meibomian Gland Disease Committee, Tear Film and Ocular Surface

Society