ENDOCRINE SYSTEM ENDOCRINE SYSTEM

A system, which has secretion

function of hormones to

coordinate physiological

function of the body

SIKLIK AMP HORMON INSULIN di MEMBRAN SEL

PENGATURAN FUNGSI SEL

FEED BACK MECHANISM

• Negative / Positive feed back mechanism

• Is a hormon secretion process :

INCREASE OR DECREASE

Depend on the body situation needed,

so that the body’s physiological functions will be performed normally

The INCLUDED GLANDS : The INCLUDED GLANDS : 1. HYPOPHYSE

2. THYROID

3. ADRENAL

4. PANCREAS

5. GONAD

6. PLACENTA

HYPOPHYSE

LOCATION : Foramen hypophysialis

in basis cranii

LOBUS : ANTERIOR - ADENOHYPOPHYSA cromophob cells

Cromophyll cells (acidophyl & basophyl cells)

MEDIUS

POSTERIOR - NEUROHYPOPHYSA

MICROSCOPIS

HORMONE

GONADOTHROPIN FEED BACK MECHANISM

THE ROLE OF FEMALE REPRODUCTIVE HORMONES

PERANAN HORMON REPRODUKSI (PRIA)

THYMUS GLAND ( 2 YEARS OL CHILD)

Lobus :1. Superior & Inferior (dextra – sinistra) 2. Pyramidal

THYROID GLAND

THYROID AKTIF THYROID INAKTIF

MICROSCOPIS

KELENJAR PARATIROID (MIKROSKOPIS)

THYROXIN HORMONE REGULATION YODIDA OXIDATION

PARTS :1. Medulla (inside)

2. cortex (outside) : Zona granulosa Zona faciculata Zona reticularis

ADRENAL GLAND

MICROSCOPIS

HORMONES :

• Medulla : Epinephrin

Nor epinephrin

• Cortex :

Zona granulosa Mineralcorticoid

Zona faciculata Glucocorticoid

Zona reticularis Sex

NEGATIVE FEED BACK MECHANISM

GLUCOCORTICOID REGULATION MECHANISM

PANCREAS GLAND

PARTS :

1. CAPUT

2. CORPUS

3. CAUDA

MICROSCOPIS

HORMONES :

• LANGERHANS :

Alpha cells GLUCAGON

Beta cells INSULIN

Delta cells SOMATOSTATIN

ADRENAL GLAND HYPERSECRETION

CUSHING SYNDROMA (ACTH)ADRENOGENITAL SYNDROMA

(SEX HORMONE )

THYROXIN HYPERSECRETION (BASEDOW – EXOPTHALMUS)

THYROXIN HYPERSECRETION (MIXEDEMA)

THYROID GLAND DISORDES