EMD Millipore Process Solutions

Ernie Desmarais – Account Manager

In Bioprocess our innovation is focused on providing you with the highest performing products in flexible, easy to use formats

Viresolve® ProHigh productivity viral clearance**ProSep® Ultra Plus

Highest capacity Protein Acapture resin

Cogent® µScaleVersatile semi-automated bench top TFF system for process development

MilliPROBE™

Reliable, sensitive, and accurate microbial detection in just 4 hours

ChromaSorb™

Single use chromatography membrane adsorberfor robust impurity removal**

Pellicon® 3High performance TFF cassettes with Biomax membranes LucraTone™

Animal-free cell culture supplements

Cell-Prime™Animal-free cell culture supplements

** launching later this year

In Bioprocess our innovation is focused on providing you with the highest performing products in flexible, easy to use formats

Millipore Express® SHF & SHR Media in SSCSterile, high flux and high retention filters in Opticap ® XL small scale capsules

Mobius® BinsStainless steel bins for faster, convenient product transport and storage

Millistak+® Pod Filters with X0HC and Vaccine Media

Scalability in easy-to-use format **

Solvex™ Filters®Reliable sterilizing-grade filtersfor solvents

Mobius® Standard AssembliesDisposable assembly solutions for media/buffer prep, clarification, TFF and virus filtration **

Lynx® 1” Sterile ConnectorGamma-compatible, disposable connector **

BeviStat™Rapid microbial detectionin beverages

** launching later this year

Service &Support

•Develop the•Process

•Express the Protein

•Separate& Purifythe Protein

•Test for Contamination

Process Monitoring Tools

Protein Expression, Cell Culture Supplements

Filtration, Chromatography, Mixing, Disposable Solutions

That can be integrated into solutions across every step in your manufacturing process

Technologies that touch every step in Downstream Processing

Mixing Transport & Storage Buffer

Prep

Environmental Monitoring Sterile Sampling Mycoplasma Screening Sterility TestingTraditional & Rapid Microbial Monitoring

SecondaryClarification

PrimaryClarification

Protein A Column

VirusInactivationColumn

Protection

PostNeutralizationClarification Column

Protection

Column Protection

CEXMembraneAdsorber Viral

ClearanceUltrafiltrationDiafiltration Filling

BulkDrugSubstance

Final SterileFiltrationProcess Monitoring:

SterileMediaPrep

Cell CultureSupplements Bioreactor

SterileVent

SterileMediaFiltration

Cell Line Engineering(UCOE™ Technology)

Environmental Monitoring Sterile Sampling

Mycoplasma ScreeningSterility Testing

Traditional & Rapid Microbial Monitoring

And an expanded offering in Upstream Processing

Mixing Transport & Storage BufferPrep

Process Monitoring Tools:

Combined with applications expertise and Regulatory Assurance Services to support your process optimization

Real-time, at-line testing –process control Virus and Mycoplasma testing

Disposable Processes High Capacity Filters and Resins

Next generationAnimal-Freesupplements in disposable containers

Enhanced proteinexpression

UpstreamProcessOptimization

Downstream Process

Optimization

Process MonitoringTools

ApplicationsExpertise & Services

=>> High performance products, flexible formats and applications expertise

Delivered directly to you through a global network of 400 technical personnel

Sales Application Specialists - 190 Sales & Key Account Management - 30

Technical Service - 45

Field Service - 15

Process Development Scientists - 15

Technology Managers - 25

Bioprocess Engineers - 30 Access Lab Services - 50

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Thank You !