Earomics part 2

Extended to GSR & EDA

GSR= Galvanic Skin Response

EDA= ElectrodermalActivity

Prof.Dr.O.Ferrer‐Roca, 2015

https://player.vimeo.com/video/133534456

CIRCUIT STICKERS


Bioimpedance‐BIA•Early detection of malnutrition the measured Phase angle, the body cell mass (BCM) and the ratio between body cell mass and extracellular mass (ECM) as well as the nutrition index (R/Xc ) , extra and intracellular water (ECW,ICW) , total body water (TBW) Lean body mass (FFM) , Resting energy expenditure (REE)are the most meaningful body composition parameters


Body composition‐Hydration‐Nutritional status

Resistance (R), Reactance (Xc), Phase angle (φ)


ResistanceIs the real part of impedance; a device with a purely resistive impedance exhibits no phase shiftbetween the voltage and current.

ReactanceIs the imaginary part of the impedance; a component with a finite reactance induces a phase shiftbetween the voltage across it and the current through it. A purely reactive component is distinguished by the sinusoidal voltage across the component being in quadrature with the sinusoidal current through the component. This implies that the componentalternately absorbs energy from the circuit and then returns energy to the circuit. A pure reactance willnot dissipate any power.

Capacitive reactance o CapacitanceHas a purely reactive impedance which is inversely proportional to the signal frequency. A capacitor consists of two conductors separated by an insulator, also known as a dielectric.

Bioimpedance‐ BIA•LEAN BODY MASS (FFM)

1. Cell mass (BCM), is the most active metabolic compartment of the body and one of the most important keys to determine a subjects nutritional status measured in the NUTRITIONAL INDEX (R/ Xc).

2. Extracellular mass (ECM), another component of lean mass, contains all the metabolically inactive parts of the body including extracellular water (ECW).

• TOTAL BODY WATER (TBW) composed by intra and extracellular water.1. These two fluid compartments are tightly regulated. It has been shown that cellular

hydration (ICW) is an important regulator for protein catabolism. 2. An increase in extracellular water (ECW) may indicate disturbance in the cellular

membrane and is a typical sign of malnutrition, even if weight stays the same and body fat is within a normal range.


EDA = Electrodermal activity•Property of the human body that causes continuous variation in the electrical characteristics of the skin .

• Known as skin conductance, galvanic skin response(GSR), electrodermal response (EDR), psychogalvanicreflex (PGR), skin conductance response (SCR), and skin conductance level (SCL).

• Skin resistance varies with the state of sweat glands in the skin. Sweating is controlled by the sympathetic nervous system, and skin conductance is an indication of psychological or physiological arousal.


If the sympathetic branch of the autonomic nervous system is highly aroused, then sweat gland activity also increases, which in turn increases skin conductance.

Tonic changes: 1‐30 microsiemensPhasic changes: .05 ‐ 5 microsiemens


Systems that influence the EDA

• Locomotor system:

* controlling brain structures = frontal lobe motor processing areas and motor areas in the brain stem (medulla & pons)* function = an anticipatory increase in EDA that allows for a response to potentially dangerous stimuli that requires a motor response

• Orienting‐arousal system:* controlling brain structures = prefrontal areas of the frontal lobe, hippocampus, amygdala, RAS * function = part of the orienting response produced by the limbic system that is seen in response to dangerous or novel stimuli

• Thermoregulatory system:* controlling brain structures = hypothalamus* function = not so related to cognitive functions, a response by this system is generated either in order to maintain normal homeostasis or in response to physical trauma


GSR= Galvanic skin response


GSR, standing for galvanic skin response, is a method of measuring the electrical conductance of the skin. Strong emotion can cause stimulus to your sympathetic nervous system, resulting more sweat being secreted by the sweat glands. Grove –GSR allows you to spot such strong emotions by simple attaching two electrodes to two fingers on one hand

Multifunction tablet


Extended in Fluorometrics and colorimetrics


http://catai.net/blog/2015/09/biostamps‐3d‐printed/

Extended to EEG


Extended to eating habits


Extended to Glucosae

NIR glucometer byArduino

InGaAs photodiode, 8 LEDs(2 x Green, 2 x NIR @ 1550nm, 1 IR @ 960nm, 1 Red) an Atmega328p, and the circuits required to run those. Also it contains a small LiPo in order to be able to test, or take training data. Two separate circuit boards and the ADC is channeled through an MCP3421 and then i2c goes across a connector at the bottom which also supplies the regulated 3.3V


NIR glucometer –Open source• green LED, a red LED, IR LED, and a 1550nm NIR LED. The green is used to determine how much skin is in the way, the Red and IR are used to determine the volume of blood being measured, and with the volume of blood you can use the 1550nm NIR LED to determine the amount of glucose.


NIR gluc –GlucoNIR™‐VivaScan™ ‐LighTouchMedical ™

CONSENSUS ERROR GRID


Photoacustic spectroscopy


using three kinds of technologies: ultrasound, electromagnetic, and thermal. You just clip

the GlucoTrack sensor onto your earlobe and within a minute, it sends your BG data through a headphone‐style cord to a smartphone‐sized handheld controller. And that's where the glucose reading is displayed or even verbally announced.

GlucoWise

• unique sensor and a nano‐film

• passing low‐power radio waves through the body

• Electromagnetic waves at specific frequencies can be used to detect blood glucose

• The metamaterial technology was initially developed to enable a novel diagnostic imaging technique, using safe radio waves instead of ionizing x‐rays.

• Metamaterials make it possible to bend light around an object making it seem that it’s not there, so these seemingly preposterous sci‐fi scenarios are in fact within the realms of probability


C8 Medisensors

• Raman spectra, a unique Raman “fingerprint”

• belt around the waist. Rather than puncturing the skin, the sensor sits close against the skin, and small drop of gel helps to seal any air gaps. The technology behind the HG1‐c is complicated, but in a nutshell: a special camera, called a raman spectrometer


BIOSTAMPS


Golden temporal tatoos

TEMPORARY TATOOUniv.of California


BLOOD GLUCOSAE

Way to stick it


4P (preventive‐pervasive‐proactive‐personalized)

DIY data HSD (health small data)


Earomics part 2

Healthcare

Transcript of Earomics part 2