IMSTA’S 2015 ANNUAL CONFERENCE making it happen enabling change in healthcare

Prof. Deirdre McNamara

Developing Medical Devices in a Healthcare Environment

25/03/2015

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE

“A new funding model, Implementing clinical pathways, Integrating system wide care. Can the MedTech Industry help make this happen? “

Funding

Cost reduction / Cost effectiveness

Clinical Pathways

Optimal patient care / outcomes / development & translation

System integration

Technology / eMedicine /

Developing Medical Devices in a Healthcare Environment

Industry enables health care system performance,

access, quality and sustainability

Collaboration and a partnership approach to

efficient healthcare solutions can make it happen

Here to help healthcare providers with the most

clinically and cost effective diagnostic and

therapeutic solutions. “Two way street”

Trinity College Dublin, The University of Dublin

Medicine and the Patient

Intuitive Medicine

• Highly trained expensive professional

• Intuitive Experimentation

• Pattern Recognition

Empirical Medicine

• Evidence Based

• Data shows one way better than the other

Precision Medicine

• Diagnosed precisely

• Predict treatment effect

Traditional Medicine Technological Enabler

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE The Focus In Medical Research

Heart Disease Cancer Immunology Neurosciences Molecular Medicine Genomics

Bench

Bedside Precision Medicine at the Point of Care

Medical Technology

Understanding Functional Aspects to Disease

Trinity College Dublin, The University of Dublin

Research and Development

Research & Development

SME

Successful Indigenous - Contract Manufacture & Design

Multinationals - Manufacture

FDI

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

200

Companies

25,000 Jobs

€7.2 billion

Exports

Building Ireland’s Smart Economy

A Framework for Sustainable Economic Renewal

Trading and Investing in a Smart Economy

A Strategy and Action Plan for Irish Trade, Tourism and Investment

Commercial Success In Medical Technology In Ireland

2010

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

Product Life Cycle

Clinical &

Scientific Testing

Concept

Prototype

Preclinical

Clinical

Manufacturing

Marketing

Commercial Use

Obsolescence Involving Clinicians

& Other

Healthcare Professionals

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

Industry, Academia & Healthcare

Patient Driven Innovation

Centres Where Healthcare is

Delivered Biotechnology

Sector

Universities and College

Commercial Entities

Hospitals

Patients Homes

Health Care Centres

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

Patient Driven Innovation in Gastroenterology

Clinicians

Bioengineers

Physicists

Other Professionals

Gastroenterology

&

Endoscopy

•Identify needs •Design •Translating innovations •High quality research programs •Research hub for innovations from outside group •Opportunities to develop, adapt and apply devices in a quality research environment

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

www.medicine.tcd.ie/tagg/

We are a multidisciplinary research and clinical team

comprising Gastroenterologists, Surgeons, Medical

Physicists, Nutritionists, Nurses, Engineers, Scientists

and Allied Health Professionals working

collaboratively at the Adelaide & Meath Hospital

incorporating the National Children’s Hospital

(AMNCH) and St James’s Hospital Dublin with Trinity

College Dublin.

The TAGG Research Centre is affiliated with Trinity

Health Ireland (THI).

Our vision is of excellence and innovation in service

delivery and research in gastroenterology.

Trinity College Dublin, The University of Dublin

– TAGG principal investigators (PIs) collaborate with national and international colleagues across Europe, North America, Canada and Ireland as well as with small and medium sized enterprises (SMEs) and Industry partners.

– Local Collaborations

• Life Sciences Interface, Tyndall National Institute – Dr. Karen Twomey

• National Cancer Registry Ireland – Dr. Linda Sharp & Nick Clarke

• BioInnovate Ireland – Dr. Mark Bruzzi

• EndoVe – Mitamed, Dr. Kevin Soden

• Endodex Ltd – Ms Katrina Bradley

• Vasorum Ltd – Dr. Jim Coleman

IMSTA’S 2015 ANNUAL CONFERENCE TAGG Medical Device & Innovation Hub

Trinity College Dublin, The University of Dublin

Product Life Cycle

Concept

Prototype

Preclinical

Clinical

Manufacturing

Marketing

Commercial Use

Obsolescence Involving Clinicians

& Other

Healthcare Professionals

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

EndoFlip Discovery

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE New Applications: FLIP in UOS

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE New Applications: FLIP in the Lower GI Tract

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE New Applications: FLIP in the Lower GI Tract

Probe No. MODEL Catheter

Diameter

No. of CSA

Measurements

Maximum Bag

Diameter

CSA Measurement

Length

No. of

Patients

Studies

Bag Pressure

Probe 1 EMF-325N

(modified)

2.5mm 16 25mm 75mm 4 Yes

Probe 2 Custom ICV

Probe

2.29mm 12 19mm 55mm 2 Yes

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE Medical Device Innovation

The shape we're in: 10 facts about Irish obesity “As a nation, we're getting fatter to the point of a crisis. It's especially prevalent among older people, according to a new report”

Trinity College Dublin, The University of Dublin

Obesity Endoscopic Management System

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

Product Life Cycle

Clinical &

Scientific Testing

Concept

Prototype

Preclinical

Clinical

Manufacturing

Marketing

Commercial Use

Obsolescence

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

HSE figures show lengthening hospital waiting lists

Leo Varadkar admits figures will get worse but promises hospital activity will be ramped up ‘subject to finance being available’

HSE figures show delayed discharges, at 835, were a major problem back in November; the persistence of high numbers of delayed discharges after Christmas was a major contributory factor behind the trolley crisis

Health Care Innovation

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE Health Care Innovation

Trinity College Dublin, The University of Dublin

• Developing medical devices in a healthcare environment is feasible and beneficial

• Involvement of teaching hospitals in trials of devices and drugs is paramount to market success

• Performing device trials in hospitals is not straight forward and needs technical input from engineers and scientists as well as clinicians and other healthcare professionals

• TAGG model offers great opportunity as a gateway to deliver better products for more effective and economic patient care

• Industry and executive buy in “show me the money”

Conclusions

IMSTA’S 2015 ANNUAL CONFERENCE

Trinity College Dublin, The University of Dublin

IMSTA’S 2015 ANNUAL CONFERENCE

Medical Device & Innovation Team Leaders Barry McMahon Stephen Bligh

Contact Details: www.medicine.tcd.ie/tagg/ sbligh@tcd.ie

Conclusions

Thank You