Diamide Working Group F2F meeting 2011 - IRAC · - Attached for DuPont and Rallis. Bayer‟s Fame...

Insecticide Resistance Action Committee

43rd IRAC International Meeting, Washington DC, April 1-4, 2008 1

Diamide Working Group F2F

meeting 2011

Brussels, March 28th 2011

http://www.irac-online.org/index.asp



2

2011 Diamide WG F2F Mtg Agenda

Brussels, March 28th 2011

MORNING SESSION

9:00-9:30 Check-in - CropLife Building

9:30-9:45 Welcome, Introductions and Review of Agenda Verónica

9:45-10:00 Antitrust guidelines and team administration Verónica

10:00-13:00 Country Reviews LiaisonsHow can we make the country groups more active? All

Process to approve country IRM proposals John

15 minute break (11:00)

13:00-14:00 Lunch Break

AFTERNOON SESSION

14:00-15:30 Diamide IRM Issues,Company Objectives, and WG Accomplishments

John / All

15:30-16:00 Development of 2011/12 SMART objectives and goals All

16:00-16:30 Update Global Guidelines/ IRM language templates John / all

16:30-16:45 Update Bioassay Methods for Diamide Insecticides Russell

16:45-17:00 Break

17:00-17:30 Review Diamide presentation for the general day All

17:30-18:00 Feedback and suggestions All

18:00-18:30 Next meetings‟ dates and final items Verónica/ all



3

Antitrust guidelines



4

Diamide WG members

Verónica Companys Bayer Chair

John Andaloro DuPont Vice-chair

Luis Teixeira DuPont

Paula Marcon DuPont

Andrea Bassi DuPont

Robert Senn Syngenta

Russell Slater Syngenta

Ken Chisholm Nihon Nohyaku

Ralf Nauen Bayer

Alan Porter APA



5

Diamide WG – 2010/11

Meetings

– monthly conference calls. One F2F in Brussels,

– good participation

– good follow-up of actions

Main topics

– updates from Country Diamide WGs. Support them

– Philippines case. How to proceed

– Methods development

– Review of resistance development in countries



Country liasons

# Country CURRENT Global Liaison PROPOSED Global Liaison

1 Argentina John Andaloro John Andaloro

2 Indonesia John Andaloro John Andaloro

3 Malaysia John Andaloro John Andaloro

4 USA Paula Marcon John Andaloro

5 Australia John Andaloro

6 Brazil Paula Marcon Luis Teixera

7 Mexico Paula Marcon Luis Teixera

8 Philippines Paula Marcon Veronica Companys

9 Japan Nobuyuki Nonaka Ken Chisholm

10 Korea Ken Chisholm Ken Chisholm

11 Thailand Robert Senn Robert Senn

12 Vietnam Robert Senn Robert Senn

13 China Robert Senn Robert Senn

14 Spain Veronica Companys Veronica Companys

15 India Veronica Companys Veronica Companys

16 Italy Andrea Bassi

17 Morocco Andrea Bassi

18 Turkey Robert Senn

19 Canada John Andaloro



0. Haven't met yet1. Understand Objectives 2. Meet and Organze3. Review Antitrust4. Review Global Guidelines

5. Select High Risk Insects & Markets 6. Develop Plan to Communicate MOA7. Develop IRM Guideline Plan by Crop8. Develp Communicate & Educate Plan

9. Act if "R" Occurs10. Communicate Social Adv11. Implement 6, 7, & 812. Work on more markets

* Visited by member of Global Diamide WG

Country Diamide Working Group Progress: Update 2011, March

# Global Liaison Country Relative to the Steps in the Country Guidance Tutorial

1 John Andaloro Australia* 0 1 2 3 4 5 6 7

2 John Andaloro Argentina 0 1 2 3 4 5 6 7 8 9 10 11 12

3 Luis Teixera Brazil 0 1 2 3 4 5 6 7 8

4 Robert Senn China* 0 1 2 3 4 5

5 Veronica Companys India 0 1 2 3 4 5 6 7

6 John Andaloro Indonesia* 0 1 2 3 4 5 6 7

7 John Andaloro Italy 0

8 Ken Chisholm Japan 0 1 2 3 4 5

9 Ken Chisholm Korea 0 1 2 3 4

10 John Andaloro Malaysia 0 1

11 Luis Teixera Mexico 0 1 2

12 Morocco 0

13 Veronica Companys Philippines* 0 1 2 3 4 5 6 7 8 9 10 11

14 Veronica Companys Spain 0 1 2 3 4 5 6 7 8 9 10 11

15 Robert Senn Thailand* 0 1 2 3 4 5

16 Robert Senn Turkey 0

17 John Andaloro USA* 0 1 2 3 4 5 6 7 8

18 Robert Senn Vietnam* 0 1 2 3 4



8

Country reviews



9

Country reviews

Vietnam


Vietnam Diamide WG Update

Major Milestones

1. Date group was formed: Feb 10, 2009

2. List of Members: Syngenta VN, DuPont VN, Bayer VN

(Consultant: Dr. Nguyen Truong Thanh from Plant

Protection Institute)

3. How many meetings has the group had to date (F2F vs.

audios): 4 (3 face to face meetings + 1 telec meeting).

4. What are the prioritized crop markets and high risk insects

the group has elected to work on initially (2009-2010): Rice

& cabbage

5. Country Group Update by Crop Market: Rice & cabbage.

Crop: Rice

1. What diamide active ingredients are already registered:

• CTPR solo registered by DuPont under trade name Prevathon 5SC for control LF, SB on rice.

• CTPR mixture registered by Syngenta under trade name Virtako 40WG on rice (LF, SB, BPH)

2. Share electronic versions of labels for currently available diamide products:

(see next slide)

3. Show IRM language for each of the labels, review harmonization of IRM label language:

the languages are all in Vietnamese.

4. Share final document with written IRM recommendations tailored for crop market #1.

• On Prevathon 5 SC (main label of DuPont), it recommends that do not tank mix or frequent

application Prevathon on rice with other products in the same group of 28 . Both cabbage

and rice, it recommends use Ammate (Indoxacarb) first then come with Prevathon.

• On Virtako 40 WG ( sub-label of Syngenta), it recommends that to reduce resistance of LF &

SB, do not use the product in the same group 28 (Diamide) to tank mix or alternatively

applied with Virtako 40 WG. (we have not launched Virtako 300 SC) on vegetables.

5. Are these recommendations being promoted by all member companies in the market place:

Yes.

Are these recommendations supported by influencers (consultants, regulators)? Provide

examples, if available:

No. It is not paid attention by authority when their efficacies are still OK

Labels pictures.

Crop : Cabbage

1. What diamide active ingredients are already registered:

• CTPR solo registered by DuPont under trade name Prevathon 5 SC for control DBM on

cabbage.

• CTPR mixture registered by Syngenta under trade name Virtako 300 SC on cabbage &

tomato (flea beetle, aphids)

• Flubendiamide registered by Nihon Nohyaku under trade name Takumi 20 WG on

cabbage/DBM

2. Share electronic versions of labels for currently available diamide products (see next

slide)

3. Show IRM language for each of the labels, review harmonization of IRM label

language: the languages are all in Vietnamese.

4. Share final document with written IRM recommendations tailored for crop market #1.

• On Prevathon 5 SC (main label of DuPont), it recommends that On cabbage, it

recommends use Ammate (Indoxacarb) first then come with Prevathon.

• Syngenta has not yet launched Virtako 300SC on vegetables.

5. Are these recommendations being promoted by all member companies in the market

place:

Yes.

Are these recommendations supported by influencers (consultants, regulators)?

Provide examples, if available:

No. It is not paid attention by authority when their efficacies are still OK.

Labels pictures.

They are submitting dossier to

government for registration on

RLF, S. exigua. on rice and

onion.

Risk of resistance development & actions

1. Has any reduction of diamide efficacy been observed?

Not yet.

2. Where do you see the major risk of resistance development and

why? crop, practices

Very high risk are in Veggies:

-Plutella xylostella on Brassica (Cabbage, cauliflower…) – high

intensity, short interval, over dose application…

- Spodoptera exigua on Bean (long bean, cove…) – Not yet registered

but growers used as their experience.

- Rice : moderate intensity because high price.

3. What actions within your country/crop would have the greatest

impact on encouraging growers to adopt IRM practices for

diamides?

Some programs from NGOs corporate with Government to train and

finance for growers: IPM, ICM, GAP… Recommendation from

supplied companies on labels and in farmer meetings.


18

Country reviews

India


Country Diamide WG UpdateMajor Milestones

• Date group was formed- 2nd February , 2010

• List of Members (names, companies, non-industry consultants)

How many meetings has the group had to date (F2F vs. audios)

- One Audio on 15th February , One face to face meeting on 5th March,

One face to face meeting on 20th September and one audio (with

marketing members) on 16th December, 10.

• What are the prioritized crop markets the group has elected to

work on initially (2009-2010)? Rice and Cabbage

• Country Group Update by Crop Market

S. No. Name Company E-mail Mobile Number

1 Rajul Edoliya DuPont [email protected] 919810503126

2 Vineet Singh DuPont [email protected] 919898905248

3 K V V Satyanarayana Bayer [email protected] 919819442876

4 Subhrabitan Das Bayer [email protected] 919820490563

5 Rajendra Deshmukh Syngenta [email protected] 919872066797

6 Rakesh Goel Syngenta [email protected] 919729064321

7 Manickam Asaithambi Nihon Nohyaku [email protected] 819017997198

8 S. Mallikarjunappa Rallis [email protected] 919243474898

India

Country Diamide WG Update

Cabbage• What diamide active ingredients are already registered?

- Takumi 20 WG, Coragen 20 SC,

- Share electronic versions of labels for currently available diamide products.

- Attached

• Review and compare these labels. In particular, review harmonization of IRM

label language.

- Coragen 20 SC label has incorporated a part of IRM label language, Takumi ( Rallis)

shall do the same at the time of next label expansion.

• Share group‟s final IRM recommendations tailored for crop market #1.

- Final IRM recommendation has not been released so far.

• Are these recommendations being promoted by all member companies in the

market place? Are these recommendations supported by influencers

(consultants, regulators)? Provide examples, if available.

- Shall be adopted by all member companies once we get an alignment on the final

recommendation.

India


Rice• What diamide active ingredients are already registered?

- Takumi 20 WG, Fame 48 SC, Coragen 20 SC, Ferterra 0.4 % GR

• Share electronic versions of labels for currently available diamide products.

- Attached for DuPont and Rallis. Bayer‟s Fame label is already available with

Veronica

• Review and compare these labels. In particular, review harmonization of IRM

label language. Coragen 20 SC and Ferterra 0.4 % GR label have incorporated a

part of IRM label language, Takumi ( Rallis) and Fame (Bayer) shall do the same

at the time of next label expansion.

• Share group‟s final IRM recommendations tailored for crop market #1.

- Final IRM recommendation has not been released so far.

• Are these recommendations being promoted by all member companies in the

market place? Are these recommendations supported by influencers

(consultants, regulators)? Provide examples, if available.

- Shall be adopted by all member companies once we get an alignment on the final

recommendation.

India


Rice

• Next steps.Our final communication is in final stage and the same was shared with the R&D and

marketing members of all member companies on 16th December audio. During the

audio several queries were addressed. Few un-answered queries were forwarded to

the global diamide group for their inputs. After receiving the inputs the same were

shared with all members.

The implementation part which was due by February‟2011 is running behind the schedule

to beginning of year and lot of other meetings schedules.

India

Risk of resistance development

and actions

1. Has any reduction of diamide efficacy been observed? No

2. Where do you see the major risk of resistance development and why? crop, practices-Brinjal (Egg Plant)

3. What actions within your country/crop would have the greatest impact on encouraging growers to adopt IRM practices for diamides?Common message at market place, conducting farmer workshops and their trainings on IRM aspect. Informing them about the alternate and effective chemistries they can incorporate in their schedule. Making the trade channel aware of the Diamide Working Group‟s efforts and the seriousness behind it.

India

INDIA WG Update

India Rice Strategy (under review)

• Always follow the directions for use on the product label.

• For the control of rice stem borers and leaf folder, there are two main windows ( 1st

window upto 35 DAS/DAT & 2nd window from around 40-80 DAS/DAT) when insecticide

applications are required to manage these pests.

• Diamides should be applied either in „1st window‟ or „ 2nd window‟ but can not be applied in both

the windows. The main reason is to avoid exposure of two consecutive generations of

the target pest (Stem borer and leaf folder) by the Diamides.

• Within a particular window, diamide insecticides may be applied more than one time, as

long as the residual activity of the combined sequence of applications does not exceed

the period of time of a single generation of the target pest.

• The total exposure period by diamide insecticides should never exceed 50% of the crop cycle.

• In areas where 2-3 crop seasons of rice are grown in a year, application of diamide

should not be repeated in the 1st window of next season crop if it was applied in the 2nd

window of previous crop season or vice versa.

India

INDIA WG Update

Germination

1st. Gen.

Early

Tillering

0 -10 DAT

Active

Tillering

11 -30 DAT

Vegetative Stage Reproductive Stage

Maximum

Tillering

31 -50 DAT

Panicle

Initiation

51 -60 DAT

Booting

61 -80 DAT

Heading/ Milky

81 -100 DAT

Ripe/ Maturity

101 - 120DAT

YRSB

&

LF

2nd. Gen.

Group 28 InsecticidesNon-Group 28 Insecticides


Example 1 India

INDIA WG Update

Germination

1st. Gen.

Early

Tillering

0 -10 DAT

Active

Tillering

11 -30 DAT

Vegetative Stage Reproductive Stage

Maximum

Tillering

31 -50 DAT

Panicle

Initiation

51 -60 DAT

Booting

61 -80 DAT

Heading/ Milky

81 -100 DAT

Ripe/ Maturity

101 - 120DAT

YRSB

&

LF

2nd. Gen.

Group 28 InsecticideNon-Group 28 Insecticides Non-Group 28 Insecticides


Example 2 India

INDIA WG UpdateIndia Cabbage Strategy (under review)

• Always follow the directions for use on the label of each product.

• For management of diamondback moth (DBM), there are 4 main windows when

insecticide applications are required to protect the crop from damage by this pest. The

first window is from nursery to 20 days after transplanting (DAT) , the second window is

from 21-50 DAT, third window is from 51-80 DAT and 4th window is from 80 DAT and

beyond.

• Diamides should be applied either in the „1st ‟ and „ 3rd window‟ or in „2nd ‟ and „ 4th window‟

• The main reason is to avoid exposure of two consecutive generations of the target pest

by the Diamides. If diamides are applied in the first window, they should not follow with

diamide insecticides in the 2nd window. However, he can use two „back to back‟ diamide

applications in the „diamide active window‟.

• Alternatively, if a grower chooses to apply a diamide insecticide for the control of DBM

in the 2nd window, then he should not apply diamide insecticides in the 1st or 3rd

windows.

• The total exposure period by diamide insecticides should never exceed 50% of the crop cycle.

• In case, several cabbage crops are grown successively, application of diamides should

be avoided in the 1st window of next season crop if it was applied in the last window of

the previous crop season.

India

INDIA WG Update India Cabbage Strategy (under review)

Seeding/

GerminationPre-cupping/ CuppingCotyledon/ Seedling Head Formation Head Fill Mature (Harvest)

0 10 20 30 40 50 60 70 80 90 100 daysNursery

Transplanting from nursery to field

Gen. n1

DBM

Gen. n2 Gen. n3 Gen.

etc.

Group 28 Insecticide Group 28 Insecticide

Non-Group 28

Insecticides

Non-Group 28

Insecticides

Example 1 India

INDIA WG Update India Cabbage Strategy (under review)

Seeding/

GerminationPre-cupping/ CuppingCotyledon/ Seedling Head Formation Head Fill Mature (Harvest)

0 10 20 30 40 50 60 70 80 90 100 daysNursery

Transplanting from nursery to field

Gen. n1

DBM

Gen. n2 Gen. n3 Gen.

etc.

Group 28 Insecticide Group 28 Insecticide

Non-Group 28

Insecticides

Non-Group 28

Insecticides

Example 2 India

IRM Language on Coragen Label

India

Flubendiamide 20 WG – approved label claim

Takumi

Name of

Crop

Common name of

pest

Dosage per hectare Waiting

period from

last spray

to harvest

(in days)

MRL fixed in

India

(ppm)a.i.

(g)

Formulation

(g)

Dilution in

water

(litre)

RiceStem borer

Leaf folder25 125 500 30 0.10

CottonAmerican

bollworm50 250 500 30 0.10

Pigeon

peaPod borer 50 250 500 30 0.05

CabbageDiamondback

moth12.5 62.5 500 7 0.05

Tomato Fruit borer 50 250 500 5 0.07

Diamide IRM statement has not been incorporated so far on Takumi label. Rallis plans to do the same at the time of next label

Expansion.

India

Coragen label

SR. NO. PRODUCT NAME CROPS ON LABEL PEST

RECOMMENDED

DOSE/ HECTARE

(Formulation/

hectare)

PHI

(days)

Rice

Stem borer (Schirphophaga

incertulas ) and Leaf folder

(Cnaphalocrocis medinalis )

150 ml/ha

47

CabbageDiamond Back Moth (Plutella

xylostella )50 ml/ha

3

Cotton

American Boll Worm

(Helicoverpa armigera ), Spotted

bollworm (Earias vittella ),

Tobacco caterpillar (Spodoptera

litura )

150 ml/ha

9

Termite (Odontotermes obesus/

Microtermes obesi ), 500-625 ml/ha

Early Shoot Borer (Chilo

infuscatellus)375 ml/ha

Top borer (Scirpophaga excerptalis) 375 ml/ha

6

Ferterra

(Chlorantraniliprole

0.4% GR)

Rice

Yellow Stem Borer

(Scirpophaga incertulas ),

Paddy Leaf Folder

(Cnaphalocrosis medinalis )

10 kg/ha 53

208

LABEL RECOMMENDATION

4

Coragen

(Chlorantraniliprole

18.5% SC)

Sugarcane

India


34

Country reviews

Philippines


Philippines Diamide WG Update

Major Milestones

1. Date group was formed- 2Q 2009

2. List of Members (names, companies, non-industry consultants)

Rhoel Suiza, Technical, Syngenta

Ariel Anico, Marketing , Syngenta

Nap Saavedra, Corporate Affairs, Syngenta

Florence Vasquez, Technical, Bayer CropScience

Aaron Cano, Marketing, Bayer CropScience

Ronald Arabit, Stewardship/Marketing, Bayer Cropscience

Philippines

Philippines Diamide WG Update

Major Milestones

2. List of Members (names, companies, non-industry consultants)

Oscar Edralin, Technical, Dupont

Ronald Brian Flores, Marketing, Dupont

Philippines

Philippine Diamide WG Update

Major Milestones

3. How many meetings has the group had to date (F2F vs. audios)

since its initiation.

10 ( 11 including tomorrows meeting)

4. What are the prioritized crop markets and high risk insects the

group has elected to work on initially (2009-2010)

Eggplant and cabbage

Country Group Update by Crop Market (where are you relative to

the Diamide IRM Country guidelines)

We are already on the printing stage of the finalized educational

material. As far our scheduled educational program, we are already

preparing for the worskhop which will be initially held in May. (attached

see project timelines)

Philippines

Crop Cabbage

1. What diamide active ingredients are already registered?

flubendiamide, chlorotraniprole, chloronatriprole + thiametoxam

1. Share electronic versions of labels for currently available diamide products. ( same

as before)


language or progress being made to achieve harmonization.

3. Have you developed a document with IRM recommendations tailored for crop market

#1? Please share growth stage diagrams (crop and pest phenology) showing the

recommendations.

Yes ( please find attached educational material)


place? Are these recommendations supported by influencers (consultants,

regulators, univ experts)? Provide examples, if available.

Will be promoted together with the registrants in the forthcoming scheduled

educational campaign program and other stakeholders like government, research

institutions and academe

Philippines

Crop : Eggplant

1. What diamide active ingredients are already registered?

flubendiamide, chlorotraniprole, chloronatriprole + thiametoxam

1. Share electronic versions of labels for currently available diamide products. ( same

as before)


language or progress being made to achieve harmonization.

3. Have you developed a document with IRM recommendations tailored for crop market

#1? Please share growth stage diagrams (crop and pest phenology) showing the

recommendations.

Yes ( please find attached educational material)




Will be promoted together with the registrants in the forthcoming scheduled

educational campaign program and other stakeholders like government, research

institutions and academe

Philippines


and actions


Yes

2. Where do you see the major risk of resistance development and why? crop, practices

We see major risk in cabbage for DBM control

The following are the causal factors:

• no alternation of products, Farmers use same MOA

• under/over dosage

• not following recommendation on frequency and timing of application

• asynchronous planting

Philippines

Risk of resistance development and

actions

1. What actions within your country/crop would have the greatest impact on encouraging growers to adopt IRM practices for diamides?

Educational campaign program which will be conducted in 2 phases

1. Train the trainers program which will be attended by company

representatives, government officials, university staff. Competent/reliable speakers from the universities will be invited

2. Farmers training- approx 5000 farmers will benefit from this exercise

Monitoring of resistance ( with pre and post evaluation)

Philippines

Philippine Vegetable IRM Recommendations and Training Plans

IRAC Philippines Diamide Working Group

Sixth International Workshop on Management of the Diamondback Moth

2011, March 28-31:Kasetsart University, Thailand

March 21-25, 2011

Philippines

Source: Bureau of Agricultural

Statistics , 2009

Value of Production (in Billion Php)

238,353.57

76,952.2964,663.12

80,971.50

88,867.88

34,477.52

8,521.81

5,528.91

18,114.31

Palay

Corn

Coconut

Banana

Pineapple

Coffee

Mango

Vegetables

Others

Agriculture in the Philippines

Vegetables are regarded as high value crops with a

production value of about 34.5 B PHP

Farmers practice intensive insect pest control to protect their

crops from insect pests

DBM is one of the most important pest infesting vegetables

cabbage in particular. It is recognized as a high risk pest as

far as resistance development is concerned

No joined sustained efforts by all stakeholders on resistance

management

Treated Area and Application

Crop Treated Area(ha)

Number of applications

and interval

Cabbage 100% 8-12 sprays at 7 days

Chemical subgroup: Diamides

Flubendiamide and chlorantraniliprole was registered in 2006 and 2007

respectively

Current Situation on Diamides

Intensive Commercial Production Areas of Cabbage

in the Philippines

Ilocos

Benguet

Bukidnon

Davao

Cebu ( reduced sensitivity in 2010)

Summary of Survey Findings

Incidence of use

Frequency of spray

Rotation

Dosing

High incidence of diamide use

12 sprays in a season; around 70%

or higher uses diamide products

Observed overdosing

Rotation with compounds from other

chemical classes/modes of action is

generally not practiced

Based on survey of 100 farmers in Sudlon Cebu

Philippine IRAC Diamide Working Group

Formed IRAC Diamide WG in 2009: develop

IRM strategy against DBM in cabbage

Closely coordinating with IRAC International

and IRAC SEA on resistance management

Recently, IRAC was integrated in the

Product Stewardship Committee of CropLife

Philippines

IRAC Philippines Diamide WG Members

Ariel Anico

Syngenta

Aaron Cano

Bayer CropScienceRonald Arabit

Bayer CropScience

Oscar Edralin

Du Pont

Florence Vasquez

Bayer CropScience

Nap Saavedra

Syngenta

Rodel Macatula

Du Pont

Rhoel Suiza

Syngenta

IRAC Philippines Project

Develop and launch an insect resistance management program

against DBM in cabbage with the following components:

1. IRM strategy

2. Educational campaign

3. Assessment /Monitoring

IRAC Philippines Project

Educate stakeholders ( company reps, farmers, government,

and in close collaboration with research and educational

institutions involved in agriculture ) on the principles and

practice of insect resistance management

Objectives

Maintain insect susceptibility of registered compounds

as viable/effective option in integrated pest management programs

Contribute to the sustainability of Philippines vegetable

production

Provide sustainable alternatives for vegetable

insect pest management

Assess effectiveness of the program through

pre /post evaluation

Action Points

Involve all stakeholders ( government officials

including regulators, academe, extension workers,

farmers, industry)

Mechanics of the Project

Stage 1 : Train the trainers program which will

participated by company representatives

local government research and

extension staff, academe

a .Develop training module

b. Training of trainers (TOT) in project sites

c Pre and Post Assessment

Stage 2 : Farmers training

a .Production of training material

b. Training of farmers in project sites

b. Pre and Post Assessment (survey)

Train the trainers workshop will be conducted

in the following project areas

Area Crop Date # of

Participants

Benguet Cabbage May 17 100

Pangasinan Eggplant May 19 60

Cebu Cabbage June 7 30

Bukidnon Cabbage July 5 36

Davao Cabbage July 19 30

Quezon Eggplant August 2 50

Batangas Eggplant August 16 40

Farmers Training will be conducted in the following

project areas

Area Crop # of Participants

Benguet/Ilocos Cabbage 3000

Pangasinan Eggplant 400

Cebu Cabbage 400

Bukidnon Cabbage 300

Davao Cabbage 300

Quezon Eggplant 200

Batangas Eggplant 400

TOPICS IN THE IRM TRAINING

Integrated Pest Management – Dr. C.B. Adalla

General Principles of Resistance Management- Dr.E. Bernardo

Insect Resistance Management: Experience in cabbage

and eggplant- Dr L. Colting and Dr. M. Navasero

Maintaining Susceptibility to registered products ( e.g

diamides) in vegetables, An Industry responsibility- Diamide WG

Product Stewardship- CLP

Project Activities and Timelines

Activities Timeline

1. Develop educational material 2010

on maintaining susceptibility of DBM to registered

compounds e.g diamides in cabbage

2. Obtain funding from IRAC Feb 2011

3. Prepare for the training proper Feb- April 2011

to include training module development

2. Train the trainers wokshop May- Aug, 2011

3. Farmers training Nov 2011- March 2012

4. Follow ups and Post evaluation May 2012- March 2013

../../../../../florence/resistance%20management/Project%20Diamide%20timelines-final.xls

IRM Strategy

A spray program using insecticides of a different

mode of action against each generation of DBM

Maintaining Susceptibility to Vegetable

Insecticides (eg: Diamides) – An industry

responsibility

NOTE: Insecticides belonging to other modes of action and/or other means of control

„Train the Trainers“ Agenda

Time Activity Responsible

8:00- 9:00 Registration CLP

9:00- 9:05 Invocation CLP

9:05- 9:15 National anthemm All

9:15- 9:25 Welcome Message Local Govt Unit

9:25- 9:35 Overview of the Program CLP

9:35- 10:35 General principles on IRM IRAC rep

10:35- 10:40 Coffee break All

10:40- 11:20 Resistance Issues: Philippines

experience

Resource

Scientist

11:20- 12:30 Maintaining Susceptibility to

Insecticides in Vegetable Crops

CLP

12:30 – 1:30 Lunch

1:30- 2:30 Safe use / product stewardship CLP

2:30- 5:00 Field Visit All

Country%20updates/Philippines/project%20diamide%20timelines-final%20(train%20the%20trainers).xls


69

Country reviews

China


China (Country) Diamide WG Update

Major Milestones

1. Date group was formed: April 7th , 2010

2. List of :

3. Meetings since its initiation.

• 3 group meetings held by CN Diamide WG in 2010:

• April 7th , the 1st meeting held in Beijing SYN office

• June 23rd, the 2nd meeting held in Shanghai DuPont office

• Dec. 8th, the 3rd meeting held in Shanghai DuPont office

4. What are the prioritized crop markets and high risk

insects the group has elected to work on initially

(2009-2010)?

•Rice stem borer (Chilo suppressalis) and leaffolder

(Cnaphalocrocis medinalis)

•Brassica diamond back moth (Plutella xylostella)

were selected

5. Country Group Update by Crop Market (where are you

relative to the Diamide IRM Country guidelines)

• rice stem borer: 2010 start the resistance monitoring project co-

operated with NATESC and Nanjing AU in center and south China.

• rice leaffolder: Syngenta initiate the resistance monitoring project

co-operated with Guangxi AU in Guangxi province

• Brassica Diamond back moth: planning but no action so far.

CN diamide WG initiated discussion on MOA Icon (Group 28) and

resistance management statement for label

Crop _Rice__ # 1 1.What diamide active ingredients are already registered?

Ai: chlorantraniliprole and flubendiamide

Formulations: Syngenta: Chlorantraniliprole+Thiamethoxam

(20+20)%WG,

DuPont: Chlorantraniliprole 200g/L SC

Bayer: Flubendiamide + Abamectin (67+33) g/L SC

Labels in Rice: Coragen 200SC from DuPont

IRM statement: to avoid the resistance development, it was not applied more

than 2 times per season rice, and rotation application with other MoA

products.

BELT 100SC from Bayer

IRM statement: rotation application with other MoA products

Virtako 40WG from Syngenta

IRM statement: rotation application with other MoA products, not more than 3

applications

Crop _Rice__ # 1 : status today

3. Share final IRM communication document with written IRM

recommendations tailored for crop market #1. Please share growth

stage diagrams (crop and pest phenology) showing the

recommendations.

the IRM recommendation in CN was under discussion within

Diamide WG, not finalized yet.

4. Are these recommendations being promoted by all member

companies in the market place? Are these recommendations

supported by influencers (consultants, regulators, univ experts)?

Provide examples, if available.

not yet so far in CN.

Crop Vegetable_ # 2 1.What diamide active ingredients are already registered?

Ai: chlorantraniliprole and flubendiamide

Formulations:

Syngenta: Chlorantraniliprole+Thiamethoxam (100+200) g/L SC,

Chlorantraniliprole + L-cyhalothrin (100+50) g/L ZC,

Chlorantraniliprole + Abamectin (45+18) g/L SC

DuPont: Chlorantraniliprole 5% SC

Nihon Nohyaku : Flubendiamide 20%WG

Vegetable labels: Prevathon 5%SC from

DuPont

IRM recommendation: to avoid the resistance development, it was not applied

more than 3 times per crop season .

Phoenix 20%WG from Nihon Nohyaku

IRM recommendation: to delay the resistance development, it was

recommended rotation application with other MoA products, and no more than 3

times per crop season.

Durivo 300SC from Syngenta

IRM statement: rotation application with other MoA products

Ampligo 150ZC from Syngenta

IRM statement: rotation application with other MoA products, no more than 2

times per crop season.

Voliam Targo 063SC from Syngenta

IRM statement: rotation application with non IRAC 28 (diamides) and IRAC 6

(avermectins) , no more than 2 times per crop season.

Crop Vegetable_ # 2 (please, use as many slides as needed to comprehensively describe progress to date)

4. Share final IRM communication document with written IRM



recommendations.

the IRM recommendation in CN was under discussion within Diamide

WG, not finalized yet.

5. Are these recommendations being promoted by all member

companies in the market place? Are these recommendations

supported by influencers (consultants, regulators, univ experts)?

Provide examples, if available.

not yet so far in CN.


and actions1. Has any reduction of diamide efficacy been observed?

some CN cases showed the field efficacy of diamide

products was reduced, the main reason was incorrect

application methods and timing, no resistance issue so far.

2. Where do you see the major risk of resistance development

and why? crop, practices

rice stem borer and leaffolder are the major risk for

resistance development, since lots of diamide products were

registered on rice for these pest control, including Virtako,

Coragen, Belt, and CN growers had no any resistance

management consciousness so far.


and actions3. What actions within your country/crop would have the

greatest impact on encouraging growers to adopt IRM

practices for diamides?

grower training (IRM guideline) is a big issue in CN, since

large population was poor educated farmer.


88

Country reviews

Indonesia



Indonesia Diamide Working GroupMajor Milestones

1. Indonesia Diamide Working Group was formed on Oct 29, 2009 through it first meeting done

at Syngenta Research Station at Cikampek

2. Current member of the Indonesia Diamide WG are staff from Syngenta, Dupont, Bayer, and

Agricon, list of the team as updated in Mar 11, 2011 is,

Company Name e-mail

Syngenta Marsudi [email protected]

Syngenta Fei Ling [email protected]

Syngenta Agus Triwiyono [email protected]

Syngenta Erwin Cuk Surahmat [email protected]

Bayer Tatang Rukmana [email protected]

Bayer Iwan Rahwanudin [email protected]

Dupont Iskandar Zulkarnain [email protected]

Dupont Satya Wardhana [email protected]

Agricon Agung Prasetyo [email protected]

Agricon Irma Cahayani [email protected]


mailto:[email protected]











3. Since it was performed, 5 meetings by F2F have been conducted, all the member are very actively involved

in every discussion, detail dates and locations were meeting conducted are,

1. Oct 29, 2009: at Syngenta R&D, Cikampek

2. Feb 23, 2010: at Dupont Head Office, Jakarta

3. Apr 11, 2010: at Dupont Head Office, Jakarta

4. Dec 17, 2010: at Syngenta R&D, Cikampek and

5. Mar 11, 2011: at Agricon, Bogor

Next meeting will be conducted at Bayer Head Office, Jakarta

4. The group has elected the prioritized crop markets and high risk insects to work on based on resistance risk as,

• Shallot (short periods of planting age, intensive use of pesticide with short interval of spraying)

• Cabbage (rapid development of insect population with short interval of spraying)

• Chili (targeted pest easy adapt to the use of intensive pesticide with short interval of spraying)

• Rice (misuse: low dosage, and continuous application by farmer once they got new and strong

products)

5. Current status of recommendation are,

• Fully aware with the Guideline, however still need improvement

• Application based on calendar

• Based more to the alternation spray rather than to window schedule

• Less consideration of insect target life cycle

• Number of sprays exceed to more than 50% of crop cycle



1. Shallot List of active ingredients which already registered in shallot are:

No Products Active ingredient Target Pest Recommd. Company

1 Prevathon 50 SC Chlorantraniliprole 50 g/l Spodoptera exigua 2 – 3 ml/l Dupont

2 Ampligo 150 ZCChlorantraniliprole 100 g/l + Lamda

Cyhalotrin 50 g/lSpodoptera exigua 0.1 – 0.2 ml/l Syngenta

3 Virtako 300 SCChlorantraniliprole100 g/l +

Thiametoxam 200 g/lSpodoptera exigua 0.4 – 0.8 ml/l Syngenta

4 Takumi 20 WG Flubendiamide 20 % Spodoptera exigua 50 – 100 g/ha Agricon

Current Electronic versions of labels (only Prevathon and Takumi which are available)

Prevathon

“ Maximum 4x application with 7 days interval ”

Takumi

“ Time of application starting at economic/pest threshold

level and finished 2 week before harvesting ”



IRM language on each of the labels already been used, example from Prevathon:

maximum of 4x application a long the crop cycle, or from Takumi: time of application, starting

at economic threshold.

Like that, recommendation still not follow the Diamide-IRAC Guideline fully and almost not

follow the window application schedule, and again not consider to the insect target life cycle.

Therefore in the meeting which was conducted in Mar 11, 2011, we discussed intensively to

improve and adapt the current recommendation strategy to follow the Guideline.

Results of our discussion to the possibility of using right guideline are in the following page of

charter.

The propose recommendation of spray schedule is not promoted yet to the market place,

however it will be followed up soon by all the companies member.



Life cycle of Spodoptera Exigua

is 30 days in average with first occurrence

mostly at 7 DAP.

2 generations in one crop period

Diamide Group 28 Non Group 28

Recommendation from ID diamide WG

1 7 14 21 28 42 50 57 60 DAP

Growth Stage

Diamide Group 28

Non Diamide Group

No Application

Remark :

Farmer practice in ID, most of them apply at 3-4 days interval with total of 16 sprays

Our discussion following the IRAC Guideline is to recommend of applying Diamide

product at 1st cycle of Spodoptera ( 7 – 37 DAP ) with 7 day interval, total 4 sprays,

and change to non diamide for the 2nd cycle.

Farmers practice: intensive use of products of 3-4 days intervals

1st Generation 2nd Generation

Shallot



2. Cabbage

List of active ingredients of diamide products which already registered in cabbage

Current Electronic versions of labels (only Prevathon which is available)

Prevathon:

maximum of 4x application a long

the crop period, weekly intervals.

No Products active ingredient Target Pest Recommd. Company

1 Prevathon 50 SC Chlorantraniliprole 50 g/lPlutella xylostella

Crocidolomia pavonana0.5 - 0.6 l/ha Dupont

2 Ampligo 150 ZCChlorantraniliprole 100 g/l +

Lamda Cyhalotrin 50 g/lPlutella xylostella 0.1 – 0.2 ml/l Syngenta



Growth stage

Diamide Group 28 i Non Diamides Diamide

Cabbage

Diamide Group 28

Non Diamide Group

Recommendation from ID Diamide WG, there are two option as

First recommendation applying diamide group on 1st and 3rd generation of target pest,

with 4 sprays in total.

or 2 sprays at 1st Cycle and 1 spray at 3rd Cycle for the second option of recommendation

1st Recommendation

2nd Recommendation

Life cycle of DBM

is 20 days in average with first

occurrence mostly at 1-7 DAT.

3 generations in one crop cycle

1st Generation 2nd Generation 3rd Generation?

Farmers practice: intensive use of products in 7 days intervals, 9 sprays




3. Chili List of active ingredients of diamide products which registered in chili are,


1 Prevathon 50 SC Chlorantraniliprole 50 g/l Spodoptera litura 1 – 1.5 ml/l Dupont

2 Ampligo 150 ZCChlorantraniliprole 100 g/l

+ Lamda cyhalotrin 50 g/lSpodoptera litura 0.2 – 0.3 ml/l Syngenta

3 Virtako 300 SCChlorantraniliprole 100 g/l

+ Thiametoxam 200 g/lSpodoptera litura 0.1 – 0.2 ml/l Syngenta

4 Gabbar 200 SC Flubendiamide 200 g/l Spodoptera litura 0.4 ml/l Agricon

5 Takumi 20 WG Flubendiamide 20 % Spodoptera litura 200 – 250 g/ha Agricon

Recommendation still not follow the Diamide-IRAC Guideline fully and almost not follow the

window application schedule, and again not consider to the insect target life cycle.


charter.





1 21 28 35 42 49 56 63 70 77 84 91 98 105 112 119 126 140 dat

Diamide Group 28 Non diamide group Diamide

Chili

Diamide Group 28

Non Diamide Group

Life cycle of Spodoptera litura

is 40 days in average with first occurrence

mostly at 21 DAT.

3 generations in one crop cycle



Recommendation from ID Diamide WG is

Applying diamide group on 1 st cycle with 3 sprays

and at 3rd generation with 2 sprays

Farmers practice: intensive use of products in 7 days intervals, 15 sprays



4. Rice

List of active ingredients of diamide product which already registered are,


1 Prevathon 50 SC Chlorantraniliprole 50 g/lScirpophaga incertulas

Cnaphalocrosis medinalis2 – 3 ml/l Dupont

2 Ferterra 0.4 G Chlorantraniliprole 0.4 % Scirpophaga incertulas 6.25 – 10 kg/ha Dupont

3 Virtako 300 SCChlorantraniliprolr 100 g/l

+ Thiametoxam 200 g/l

Scirpophaga incertulas

Cnaphalocrosis medinalis

Nilaparvata lugens

100 – 150 ml/ha

100 – 150 ml/ha

150 – 200 ml/haSyngenta

4 Takumi 20 WG Flubendiamide 20 %Scirpophaga incertulas


Nilaparvata lugens50 – 100 g/ha Agricon

5Spontanking 68

WP

Flubendiamide 4 % +

Monosultap 64 %

Scirpophaga incertulas


Nilaparvata lugens

0.25 – 0.5 kg/ha

0.5 – 1 kg/ha

0.25 – 0.5 kg/haAgricon

6 Gabbar 200 SC Flubendiamide 200 g/lScirpophaga incertulas


Nilaparvata lugens

150 – 200

ml/haAgricon

Recommendation still not follow the Diamide-IRAC Guideline fully and almost not follow the

window application schedule, and again not consider to the insect target life cycle.


charter.





Currently label of Virtako in Rice :

Remark :

Time of application starting at 15 days after transplanting and repeat with 15 day interval



Currently label of Ferterra in Rice :

Remark :

Currently label 1x application at 2 - 20 days after transplanting, by broadcast



Currently label of Takumi in Rice :

Remark :

Time of application starting at economic/pest threshold level and finished 2 week before harvesting

.



Life cycle RSB

30 day average with

3 generations

dat

Life cycle LFF

35 days average with

2 generations

Diamide Group 28 Non diamide group

Diamide Group 28

Non Diamide Group

Farmer practice in ID, mostly apply 4 sprays of insecticides per season.

2 times to control dead heart (vegetative stage crop), followed by 2 sprays to control

white head (reproductive stage).

ID Diamide WG recommendation is to apply only on 1st generation of RSB or LFF

With 2 sprays


1st Generation 2nd Generation

Rice

Farmers practice: apply products 4 times





and actions


There is no issue reported

2. Where do you see the major risk of resistance development and

why? crop, practices see slide 2 Shallot (short periods of planting age, intensive use of pesticide with short interval of spray)

Cabbage (rapid development of insect population with short interval of spraying)

Chili (targeted pest easy adapt to the use of intensive pesticide with short interval of spraying)

Rice (misuse: low dosage, and continuous application by farmer once they got new and strong

products)




and actions

What actions within your country/crop would have the

greatest impact on encouraging growers to adopt IRM

practices for diamides?

Under process to further following up and especially

to address the knowledge of to do the right applications

in daily activity of using diamide group of products.



Picture of the member on the meeting of Mar 11, 2011

with special guest Mr. Suhara (Marketing manager-Agricon)

from left to right: Iskandar, Erwin, Agung, Fei Ling, Irma, Iwan, Suhara, Satya, and Andre



106

Country reviews

Malaysia



107

Country reviews

Thailand


Update on DBM diamide

resistance from Thailand: causal factors and learnings

Sukonthabhirom,S;

Dumrongsak,D; Jumroon,S; Saroch,T; Chaweng,A; Tanaka,T

Status of diamide resistance in

DBM

DBM larvae in Thailand are historically

notorious for their speed of developingresistance to new products.

Diamide insecticides observed

Flubendiamide

Takumi 20%WDG

(Field recommended dose = 6 g/20 L (=60 ppm ai))

Chlorantraniliprole

Prevathon 5% SC (Field recommended dose = 30 ml/20 L (=75 ppm ai))

Thailand: Areas of Diamide Resistance by DBM

1. Bang Bua Thong district, Sai Noi district , Nonthaburi province.

2. Sali, Songphinong district , Suphannburi province.

3. Tha muang district , Kanchanaburi province. 4. Lat Lum Kaew district, Pathum Thani

Thailand - Diamondback Moth “R” to flubendiamide occurred in 15 months

DBM was the target for diamide insecticides

Insects targeting with the Diamide: mainly

DBM Spodoptera exigua and S. litura: farmers less

concerned because they can use Ammate, Success or

Rampage to control them.

The first diamide insecticide in Thailand

Flubendiamide (Takumi® 20WDG) insecticide, representing the IRAC Mode of Action Group 28, was registered in Thailand in May, 2007.

At that time, Takumi® was a novel diamide product that offered growers excellent control of diamondback moth and other lepidopteran larvae in a crucifer market where few other insecticides were adequately effective.

The products in markets for DBM control

Ammate -( indoxacarb) not effective for DBM

Success -( Spinosad) not effective for DBM

Abamectin - not effective for DBM

Rampage (chlorfenapyr) not effective for DBM

Pleo - (pyridalyl ) effective in some area

Pegasus - (diafenthiuron) effective in some area

Hachi Hachi - (tolfenpyrad) some effectiveness.

Growers are willing to rotate to other chemistries if they are effective

Other insecticides in markets for DBM control

The period from planting until harvest of Chinese

kale or Chinese radish is about 50-60 days

Farmers will start DBM sprays 15 -20 days

post planting on a 3-5 day spray interval

(high infestation could mean 10 sprays per

cropping season).

Thai farmer practice

Most farmers alternate with the existing

insecticides in the markets, however most

insecticide partners gave no maximum

protection of DBM.

At that time, farmers used flubendiamide at the

recommended dose of 4-6 g prod/20 L (with long hose high pressure pump).

Thai farmer practice

Field recommended dose of flubendiamide 20%WDG has been increasing in Thailand

Year g/20 liter a.i. (ppm)

2007 4-6 g 40-60

2009 6-8 g 60-80

2011 >12 g >120

Susceptibility of diamide

insecticide to DBM from literature

Flubendiamide

EC50 = 0.004 mg ai/liter from Japan (Tohnishi et al.,2005) J. Pestic. Sci., 30(4), 354–360.

Chlorantraniliprole

LC50 = 0.050 ppm (technical bulletin of Rynaxypyr)

LC50 = 0.221 - 1.104 mg ai/liter from China (Wang, X. et al.,2010) J. Econ. Entomol. 103(3): 843-848.

Thailand - Diamondback Moth “R” to flubendiamide

occurred in 15 months and is cross “R” to Rynaxypyr® not yet registered.

Status of diamide resistance of DBM in Thailand (year 2008-2010)

For flubendiamide and chlorantraniliprole in 2008-2010

Insecticide Population1 LC50 (mg/liter)

(95%FL)

RF2

Flubendiamide Tub Berg 0.160 (0.0366-0.811) -

Tha Muang 0.246 (0.113-0.593) 1.5

Sai Noi 10.6 (3.84-22.8) 66.3

Chlorantraniliprole Tub Berg 0.225 (0.0535-0.587) -

Sai Noi 7.97 (4.09-13.7) 35.4

1 Tha Muang, Tub Berg, and Sai Noi population was tested in 2008, 2009, and 2010 respectively.

2 Resistance factor = LC50 of a population / LC50 of the Tub Berg population, the most susceptible field population in 2009.

Status of diamide resistance of DBM in Thailand (Feb-Mar 2011)

For flubendiamide in 2011

Insecticide Population LC50 (mg/liter) (95%FL) RF2

Flubendiamide Tub Berg1 0.160 (0.0366-0.811) -

Tha Muang770.776 (123.325-26336.853) 4,817

Sai Noi65.148 (2.706-157.405) 407

Lat Lum Kaew4,256.6 (2690.1-9373.2) 26,603

1 Tub Berg population was tested in 2009.


Status of diamide resistance of DBM in Thailand (Feb-Mar 2011)

For chlorantraniliprole in 2011

Insecticide Population1 LC50 (mg/liter) (95%FL) RF2

Chlorantraniliprole Tub Berg10.225 (0.0535-0.587) -

Tha Muang19.739 (7.317-92.434) 87

Sai Noi34.364 (12.053-60.586) 152

Lat Lum Kaew174.438 (137.081-219.782) 775

1 Tub Berg population was tested in 2009.


Increased RF of DBM to flubendiamide from

past to present Tha Muang: RF 1.5 4,817 (Year 2008-2011)

Sai Noi : RF 66.3 407 (Year 2010-2011)

Increased RF of DBM to chlorantraniliprole

from past to present Sai Noi: RF 35.4 152 (Year 2010-2011)

The diamide resistance of DBM in Thailand has been increasing

Field recommended dose from the bottle label of

flubendiamide to DBM is 60 ppm ai

Tha Muang: LC50 = 771 ppm (Year 2011)

Sai Noi : LC50 = 65 ppm (Year 2011)

Lat Lum Kaew: LC50 = 4,256 ppm (Year 2011)

Field recommended dose from the bottle label of

chlorantraniliprole to DBM is 75 ppm ai Lat Lum Kaew: LC50 = 174 ppm (Year 2011)

The field recommended dose of diamide insecticide should be reconsidered

Resistance mechanisms to diamide insecticides need to be clarified

It is speculated that metabolic mechanisms

play a major role in the development of insect

resistance to diamide insecticides in

Thailand.

The breadth of cross resistance of diamide insecticide needs to be investigated.

Causal factors of diamide resistance in Thailand

Continuous plantings of crucifers

High selection pressure from frequent spraying

(over-dependency on a single mode of action)

(Farmers used flubendiamide more than 4 to 5 times per crop)

Crucifer growers minimally rotate to other non-crucifer crops such as chili and lettuce

Causal factors of diamide resistance in Thailand

Farmers always use tank mix with other

insecticides to control the same target pest

and other pests at the same time to reduce

labor cost for spraying.

Tank mix used by farmer could increase

severity of multiple/cross resistance in

DBM, if it has already obtained high

frequency of resistance gene.

In summary

The resistance of DBM to diamide insecticide

has been increasing dramatically.

Effective insecticide partners for rotation in

spraying program have to be investigated

and recommended.

Crop rotation and IPM should be performed

to decrease selection pressure.

Need to establish IRM strategy and transfer


132

Country reviews

Australia


8%20-Baker%20DBM%20IRM%202011.pps

2011 Australia Diamide WG Update

Major Milestones

1. Date group was formed… June 2010

2. List of Members (names, companies, non-industry

consultants)…..

[email protected], [email protected],

[email protected], [email protected],

[email protected], Geoff W

Cornwell/PO/DuPont@DuPont, [email protected], Guy

Kenneth Sands/PO/DuPont, [email protected],

[email protected],

[email protected],

[email protected]


Team membersGuy Sands – DuPont Product Manager

Tim O‟Grady – Bayer Market Dev Manager

Anthony De Monte – Bayer Dev Manager (Insecticides)

Stewart Learmonth – Entomologist (WA Department of Agriculture and Food)

Brendan Ahern – DuPont (Group leader)

Ken McKee – Syngenta (Field Dev Manager)

Andrew Aubert – Syngenta (Dev Manager – Australasia)

David Carey - Senior Horticulturalist (Horticulture and Forestry Science. Agri-

Science Queensland)

Alison Beattie - Development Officer (Department of Agriculture and Food WA

Manjimup

Greg Baker - Entomology Unit (South Australian Research and Development

Institute (SARDI)

Andrew Meaurant – Elders National Hort manager

Chris Monsour – Peracto Qld

Rachel Lancaster - Research Officer (vegetables) Department of Agriculture

and Food Western Australia

Geoff Cornwell – Field Development Manager (DuPont


Major Milestones

3. How many meetings has the group had to date (F2F vs.

audios) since its initiation……3

4. What are the prioritized crop markets and high risk

insects the group has elected to work on

initially…..DBM-crucifers

5. Country Group Update by Crop Market (where are you

relative to the Diamide IRM Country

guidelines)…………LEVEL 7


and actions

1. Has any reduction of diamide efficacy been observed? NO

2. Where do you see the major risk of resistance development and why? Continual Cropping

3. What actions within your country/crop would have the greatest impact on encouraging growers to adopt IRM practices for diamides?- intercompany agreement on IRM

Australian Diamide Mtg Agenda – Dec 7 2010

Agenda items

Welcome & Introduce any new team members (Brendan)

Scribe for note taking – (Geoff ?)

Review IRAC Code of Conduct & Antitrust Rules (up-front at each meeting) (Brendan)

Main focus of this meeting is on resistance management in brassicas so could we have an update from each company on how they currently promote resistance management to growers & distributors for brassicas –verbal update OK. Consider things like number of applications, window approaches, spray intervals, timing etc

DuPont strategies with Coragen (Guy Sands) 5 – 10 mins

Bayer strategies with Belt (Tim O'Grady) 5 – 10 mins

Syngenta strategies with Durivo (Ken or Andrew) 5 – 10 mins

Field feedback, what are growers actually doing – either good or bad, verbal update OK

Qld region – David Carey - 5 – 10 mins

Sth region – Greg Baker – 5 – 10 mins

WA region – Stewart – 5 – 10 mins

Elders distributor perspective – Andrew – 5 – 10 mins

Resistance wording on labels & usage in marketing publication. Brendan to go thru (see attached). Do any of the companies use this – feedback from all. 10 mins

For brassicas specifically, are the guidelines published by the regional DPI‟s sufficient or do we need more work, ie wording, funds for publication etc (see attached) (all)

Additional publications from IRAC/Crop Life

What else needs to be done to promote good resistance management in brassicas? All

What are the other key crops & pests that we could start developing resistance management strategies for? All

Summary of action items (Geoff ?)

Next audio meeting time suggestion (All)

Australian Diamide Mtg Minutes – Dec 2010

1. How is IRM promoted to growers & distributors for brassicas?

Bayer (Tim O’Grady).

-IRM message is kept simple & is passed onto growers one on one.

-give clear message to industry that Belt & Coragen have the same MOA.

-limit useage to 1-2 applications per crop. Where two applications are used, they are applied sequentially & are usually only needed under high insect pressure. Three sprays are usually not needed and are therefore avoided.

-use of Belt is generally targeted towards lep control during the “vulnerable” stage of crop development eg. broccoli-one application at buttoning initiation followed by one application 7 days later.

-“soft” chemistry such as Bt‟s & indoxacarb are recommended during the early phases of crop growth.

-also need to be fluid with Belt recommendations in crop as spray timing can be dependent on pest spectrum present. Referring to Lockyer Valley where up to 7 lepidopterous species attack brassicas.

-Group 28‟s have become a “game changer” in tomatoes & lettuce due to their MOA and as a result less methomyl is being used.

-based on many years experience with imidacloprid, the residual length of control of soil applied products can not be accurately determined due to influences from seedling media, soil types, application techniques & irrigation regimes.

-recently attended a global workshop on resistance management & Australia appears to be on its own in relation to trying to manage Group 28‟s as soil & foliar applied in the one crop segement.

DuPont (Guy Sands).

-similar positioning message as above for Coragen in relation to using the product during the important stage of crop production.

-DuPont also promotes two sequential applications but then rotate to a different MOA. A third application can be applied if required later in the crop.

2. What are growers actually doing re. use of Group 28 products?

Qld region (David Carey).

-producers have become reliant on foliar Group 28 chemistry as DBM & heliothis resistance to other chemistry has been detected.

-Group 28 chemistry has been found to be “soft” on beneficials. Another reason for its uptake.

-foliar Group 28‟s are used to control lep pests during the development of the “vulnerable” portion of the crop phase.

-the IRM strategies are published & promoted to the industry however because they are not law, they are not always adhered to.

-with low vegetable prices therefore low margins, growers are tending to use one foliar application only of the Group 28‟s. This appears to be performing well.

-feedback from the Lockyer Valley & Stanthorpe regions indicates that there are concerns for the longevity of the Group 28 chemistry.

-smaller container size allows for more rotation with different MOA chemistry.

-growers now have the opportunity to apply foliar Group 28‟s on top of soil applied Group 28‟s which poses a serious issue for resistance management.


SA region (Greg Baker).

-no direct field feedback.

-Greg is initiating a field trial this season in brussell sprouts in the Adelaide Hills to compare the persistence of chlorantraniliprole when applied foliarly (1, 2 or 3 Coragen applications 10 days apart) vs. soil applied Durivo on seedlings in the nursery. Persistence will be measured by DBM lab bioassay and possibly some chemical residue analysis of leaves. Preliminary results will possibly be available by late January, 2011.

-the use of a single MOA targeted towards specific crop growth stages where continuous crop plantings occurs actually places a significant DBM selection pressure on that molecule.

WA region (Stewart Learmonth).

-no first hand interaction with farmers.

-season has seen high DBM pressure (particularly in November) & green peach aphid pressure. GPA pressure has impacted significantly on crop establishment.

-Many growers are doing their own crop monitoring of the Durivo treated crop and when it runs out of action, they spray with a different MOA.

-One grower was using Durivo from the start of the season and based on impressive results achieved, was not certain when he would stop using it.

-a Durivo performance de-brief is planned at the end of Autumn, 2011.

-growers well aware of the need to rotate MOA‟s for DBM resistance management.

-growers plan to stop using Durivo from mid-December.

-DBM tends to attack the early development stage of the brassica crops and is less attracted to the maturing crop.

-growers tend to spray the one MOA across a range of crop growth stages at any one spray timing ie. make up one spray tank with the one MOA and apply over the entire planting.


3. What else needs to be done to promote good resistance management in brassicas?

-Geoff Cornwell suggested the industry should invest in more intensive seasonal DBM (perhaps heliothis) resistance monitoring of chlorantraniliprole & flubendiamide (& probably should also include indoxacarb, spinosad & emamectin), so as to make informed decisions from season to season on recommended use frequency of the different MOA‟s.

-Alex Mills suggested that distribution may be in a position to help fund resistance monitoring for example based on the profitability of the new chemistry being supplied through the agency system.

-Stewart Learmonth suggested HAL is keen to fund joint projects between Australia & NZ. This maybe a potential source of funding for resistance monitoring.

-Brendan Ahern suggested that the global IRAC group may be worth contacting re. sourcing funding for resistance monitoring.

Meeting closed at 3.30 pm SA time.

Action items.

Stewart Learmonth to distribute to the group, the current IRM used in WA which also incorporates Durivo & any technical bulletins sent to growers explaining how Durivo should be used from an IRM point of view.

Geoff Cornwell to source the NZ DBM brassica strategy and understand the logic behind their positioning of Durivo in this strategy.

Brendan Ahern to re-circulate Australian diamide resistance management wording options and get agreement from the group on the common wording to be used as currently there is a lack of wording consistency.

There was group consensus that the current DBM IRM‟s need to be re-drafted based on the Group 28 complexity. Any thoughts/input on improvements to be forwarded to Brendan Ahern so that they can be discussed at the next meeting.


Australian team is

debating on

whether to keep

this format or

choose something

different.


147

Country reviews

Mexico


Mexico Diamide WG UpdateMajor Milestones

1 - Date group was formed:

August 06, 2009

2 - List of MembersAbel Toledo: [email protected]

Maurilio Flores: [email protected]

Jose del Refugio Muñoz: [email protected]

3 - How many meetings has the group had to date (F2F vs. audios)

2 F2F, 2 audio and several e-mail communications.

4 - What are the prioritized crop markets and high risk insects the group

has elected to work on initially (2009-2010)?

Brassica

Tomato.

5 - Country Group Update by Crop Market (where are you relative to the

Diamide IRM Country guidelines)

N/A

What diamide active ingredients are already registered?

Flubendiamide and chlorantraniliprole

Share electronic versions of labels for currently available diamide

products.

(please see annex 1).

Show IRM language for each of the labels, review harmonization of IRM

label language or progress being made to achieve harmonization.

The final recommendation include a short version with the next points

that is included in each label:

i) Don‟t treat successive /consecutive pest generations

ii) Use the IRAC group 28 insecticide with other MOA

insecticides in a block or window, and,

iii) Don‟t apply (or treat) more than 50% crop cycle with IRAC

group 28 insecticide

Brassica and Tomato

Share final IRM communication document with written IRM



recommendations.


Are these recommendations being promoted by all member companies

in the market place? Are these recommendations supported by

influencers (consultants, regulators, univ experts)? Provide examples,

if available.

Each company has been responsible for promote the IRM 28 IRAC

group recommendations in tarket place, and in all forums, the IRM

program for 28 IRAC group has been supported by some growers

associations and technicians such as COTECO (Brassicas) and

CAADES (other veggie crops).

Brassica and Tomato


and actions

1 - Has any reduction of diamide efficacy been observed?

N/A

2 - Where do you see the major risk of resistance development and why? crop, practices

N/A

3 - What actions within your country/crop would have the greatest impact on encouraging growers to adopt IRM practices for diamides?

N/A

Annex I

• Final documents of IRM recommendations

for each one IRAC 28 group members in

Mexico for all crops included on

commercial labels

Recomendaciones generales de manejo de resistencia para las

aplicación de Belt® 480 SC

Antes de aplicar lea cuidadosamente la etiqueta y apegese a las

indicaciones señaladas para la plaga y cultivo que aquí se indican.

Con el propósito de evitar el rápido desarrollo de resistencia, evite tratar

generaciones consecutivas de la plaga objetivo con el mismo producto o

productos con el mismo modo de acción .

Aplique BELT® 480 SC usando el concepto de “VENTANAS ” alternando

bloques de tratamientos de Belt 480 SC seguido por bloques de

tratamientos con productos efectivos de diferente modo de acción.

El periodo total de exposición de todos los ingredientes activos en las

ventanas del grupo 28 aplicados durante el ciclo de cultivo no debe

exceder el 50 % de ciclo de cultivo.

Bayer Belt 480 SC

DuPont Coragen

Syngenta Ampligo 150 ZC

MANEJO DE RESISTENCIA.

Ampligo/Ampligo 150 ZC contiene un insecticida del grupo 3 de la clase química piretroides (lambda-

cyalotrina) y un insecticida del grupo 28 de la clase química de las diamidas antranílicas

(clorantraniliprol).

Para mantener la susceptibilidad de los insectos a estos grupos químicos de insecticidas se

recomienda:

•El uso de ventanas de aplicación evita la exposición de generaciones consecutivas de la misma plaga

al mismo modo de acción. Una ventana, sobre el grupo activo 28, es definida como el periodo de

actividad residual proveida por una aplicación simple o por aplicaciones consecutivas de un insecticida

del grupo 28. No aplique el mismo producto sobre generaciones consecutivas.

•Seguido de una ventana de aplicación del grupo 3 o del grupo 28 de insecticidas rote a un block de

aplicaciones con productos efectivos de diferente modo de acción antes de usar aplicaciones

adicionales de insecticidas de los grupos 3 y 28.

•El total del periodo de exposición de todas las ventanas aplicadas con el grupo 28 de insecticida a

tráves del ciclo del cultivo, (de la formación de plántulas a la cosecha), no deberá exceder mas del 50%

del ciclo del cultivo.

•Se recomienda utilizar otras prácticas de manejo integrado de plagas, para prevenir o retrasar la

aparición de biotipos resistentes a estos grupos de insecticidas.

Otras prácticas para el manejo de resistencia de insectos incluyen:

•Incorporación de técnicas de manejo integrado de plagas dentro del programa de control de insectos.

•Monitoreo de las poblaciones de insectos para detectar pérdidas de eficacia.

•Utilizar pre mezclas de insecticidas con diferente modo de acción registrados en los cultivos aquí

indicados.

•Visite el sitio del Comité para la Resistencia a Insecticidas (IRAC) en la web: http://www.irac-

online.org/.

http://www.irac-online.org/



Syngenta Durivo 300 SC

MANEJO DE RESISTENCIA:

Durivo/ Durivo 300 SC contiene un insecticida del grupo 4A de la clase química neonicotinoide

(tiametoxam) y un insecticida del grupo 28 de la clase química de las diamidas antranílicas

(clorantraniliprol).

Para mantener la susceptibilidad de los insectos a estos grupos químicos de insecticidas se

recomienda:

•El uso de ventanas de aplicación evita la exposición de generaciones consecutivas de la misma

plaga al mismo modo de acción. Una ventana, sobre el grupo activo 28, es definida como el periodo

de actividad residual proveida por una aplicación simple o por aplicaciones consecutivas de un

insecticida del grupo 28. No aplique el mismo producto sobre generaciones consecutivas.

•Seguido de una ventana de aplicación del grupo 4 o del grupo 28 de insecticidas rote a un block de

aplicaciones con productos efectivos de diferente modo de acción antes de usar aplicaciones

adicionales de insecticidas de los grupos 4 y 28.

•El total del periodo de exposición de todas las ventanas aplicadas con el grupo 28 de insecticida a

tráves del ciclo del cultivo, (de la formación de plántulas a la cosecha), no deberá exceder mas del

50% del ciclo del cultivo

•Se recomienda utilizar otras prácticas de manejo integrado de plagas, para prevenir o retrasar la

aparición de biotipos resistentes a estos grupos de insecticidas.

Otras prácticas para el manejo de resistencia de insectos incluyen:

•Incorporación de técnicas de manejo integrado de plagas dentro del programa de control de

insectos.

•Monitoreo de las poblaciones de insectos para detectar pérdidas de eficacia.

•Utilizar pre mezclas de insecticidas con diferente modo de acción registrados en los cultivos aquí

indicados.

•Visite el sitio del Comité para la Resistencia a Insecticidas (IRAC) en la web: http://www.irac-

online.org/.




Syngenta Voliam Targo

MANEJO DE RESISTENCIA.

Voliam Targo / Voliam Targo 63 SC/ Voliam Targo 6.02 SC contiene un insecticida del grupo 6

de la clase química glicósido lactone macrocíclico (abamectina) y un insecticida del grupo 28 de

la clase química de las diamidas antranílicas (clorantraniliprol).

Para mantener la susceptibilidad de los insectos a estos grupos químicos de insecticidas

se recomienda:

•El uso de ventanas de aplicación evita la exposición de generaciones consecutivas de la

misma plaga al mismo modo de acción. Una ventana, sobre el grupo activo 28, es definida

como el periodo de actividad residual proveída por una aplicación simple o por aplicaciones

consecutivas de un insecticida del grupo 28. No aplique el mismo producto sobre generaciones

consecutivas.

•Seguido de una ventana de aplicación del grupo 6 o del grupo 28 de insecticidas rote a un

block de aplicaciones con productos efectivos de diferente modo de acción antes de usar

aplicaciones adicionales de insecticidas de los grupos 6 y 28.

•El total del periodo de exposición de todas las ventanas aplicadas con el grupo 28 de

insecticida a través del ciclo del cultivo, (de la formación de plántulas a la cosecha), no deberá

exceder más del 50% del ciclo del cultivo.

•Se recomienda utilizar otras prácticas de manejo integrado de plagas, para prevenir o retrasar

la aparición de biotipos resistentes a estos grupos de insecticidas.

Otras Prácticas para el manejo de resistencia de Insectos incluyen:

•Incorporación de técnicas de manejo integrado de plagas dentro del programa de control de

insectos.

•Monitoreo de las poblaciones de insectos para detectar perdidas de eficacia.

•Utilizar pre mezclas de insecticidas con diferente modo de acción registrados en los cultivos

aquí indicados.

Visite el sitio del Comité para la Resistencia a Insecticidas (IRAC) en la web: http://www.irac-

online.org/





158

Country reviews

Brazil


Brazil Diamide WG UpdateMajor Milestones

1 - Date group was formed:

Feb, 27th, 2009

2 - List of MembersPaulo Aramaki (Syngenta) - [email protected]

Alexandre Silva (Syngenta) - [email protected]

Amauri Peloia (Syngenta) - [email protected]

Luiz Weber (Bayer) - [email protected]

Fábio Silva (DuPont) – [email protected]

Ademilson Villela (DuPont) – [email protected]

3 - How many meetings has the group had to date (F2F vs. audios)

2 F2F will meet again May 2011

4 - What are the prioritized crop markets and high risk insects the group

has elected to work on initially (2009-2010)?

Tomato (Tuta absoluta and Neoleucinodes elegantalis)

5 - Country Group Update by Crop Market (where are you relative to the

Diamide IRM Country guidelines)

Tomato: include in the label the statement for IRM (statement 3 for

Belt, statement 2 for Ampligo and on going for Premio), phenology

crop with guidance from Global Working Group and create a stamp

to guide the recommendation for IRM (depending on individual

company approval)

What diamide active ingredients are already registered?

Flubendiamide and chlorantraniliprole

Share electronic versions of labels for currently available diamide

products.

Show IRM language for each of the labels, review harmonization of IRM

label language or progress being made to achieve harmonization.


Tomato

Belt Ampligo Durivo Voliam Targo Premio

Share final IRM communication document with written IRM



recommendations.

See Phenology chart in annex 1

See Stamp in annex 1

Are these recommendations being promoted by all member companies

in the market place? Are these recommendations supported by

influencers (consultants, regulators, univ experts)? Provide

examples, if available.

Yes, all companies are recommending using IRAC guidance for

registration and label

Stamp will be included after companies approval

Tomato

Bayer

Risk of resistance

development and actions

1 - Has any reduction of diamide efficacy been observed?

N/A

2 - Where do you see the major risk of resistance development and why? crop, practices

N/A

3 - What actions within your country/crop would have the greatest impact on encouraging growers to adopt IRM practices for diamides?

N/A

Belt insecticide has flubendiamide as the active ingredient, which belong

to the Group 28. Aiming to avoid the quick resistance development, avoid to apply

Belt in consecutive generation of the pest or other active ingredient of the same

mode of action. Apply Belt using window of application, recommending rotation with

different mode of action (different group) with known efficacy for the target pest. Use

only the rates recommended in label. Consult an agronomist about recommendation

and IRM. For more information about resistance management, mode of action,

resistance monitoring, please visit the IRAC website (Insecticide Resistance Action

Committee), http://www.irac-online.org.

O inseticida Belt contém o ingrediente ativo flubendiamida, pertencente

ao grupo 28, na classificação de mecanismos de ação de inseticidas do IRAC. No

intuito de evitar um rápido desenvolvimento de resistência, não combater gerações

consecutivas das pragas alvo com o mesmo produto ou produtos com o mesmos

mecanismos de ação. Aplicar Belt usando janelas de acesso, alternando baterias de

tratamentos de Belt com outros inseticidas eficazes com mecanismo de ação

diferente. Utilizar somente as doses recomendadas no rótulo / bula. Sempre

consultar um engenheiro agrônomo para direcionamento sobre as recomendações

locais

para o MRI (Manejo de Resistência a Inseticidas). Para informações adicionais

sobre resistência de insetos, modos de ação e monitoramento de resistência, visite

o site do IRAC (Insecticide Resistance Action Committee), http://www.irac-online.org

Bayer Belt 480 SCAnnex I




Syngenta Ampligo 150 ZCSome pest can develop resistance to certain chemical group of insecticide after over using of

the product. Some degree of resistance cannot forecasted, thus the use of the product

must be in accordance with management strategies for the crop and pest. Syngenta

support action to better use to establish a long life for pest control in accordance with the

label. Ampligo is a mixture of two different active ingredients of the Group 3(Sintethic

Pyrethroids) and Group 28 (Diamides) based on IRAC mode of action. Aiming to keep

susceptible population of the pest which have a potential to develop resistance for both

chemical group, follow:

Apply Ampligo using the application “window” to avoid exposure multiple generation of the

pest to the same mode of action;

After the “window” of the insecticides of the Group 3 and Group 28, is recommended rotation

with another “window” with efficient active ingredient from other Group before to apply

the Group 3 and Group 28 in combination.

The maximum exposure window of the total Group 28 (Diamides) applied in the whole crop

cycle (from planting to harvest) cannot exceed more the 50% of the crop cycle.

Other management practice include:

1) Use other cultural practices

Outras práticas do manejo da resistência de pragas incluem:

Adotar outras táticas de controle, prevista no Manejo Integrado de Pragas (MIP) como rotação de

culturas, controle biológico, controle por comportamento etc., sempre que disponível e apropriado;

Utilizar as recomendações de dose e modo de aplicação de acordo com a bula do produto;

Sempre consultar um Engenheiro Agrônomo para o direcionamento das principais estratégias

regionais para o manejo de resistência e para a orientação técnica na aplicação de inseticidas;

Informações sobre possíveis casos de resistência em insetos e ácaros devem ser encaminhados para

o IRAC-BR (www.irac-br.org.br), ou para o Ministério da Agricultura, Pecuária e Abastecimento

(www.agricultura.gov.br).

Tomato Crop Phenology – Fresh Tomato

0 10 20 40 60 80 100 120 140 150 idade (dias)

1ªflo

res

1ª fruto

s

1ª colh

eita

Tuta absoluta – traça do tomateiro

Neoleucinodes elegantalis – broca pequena do tomateiro

Active Window #1

4-30 days

Active Window #2

60-90 days+ < 50% crop cycle (ideally < 50% of pest cycle)Note.

Group

28

Active

Window

#10-30 days

Free

Window

#131-60 days

Non-Group

28

Group

28

Active

Window

#260-90 days

Non-Group

28

Free

Window

#291-120

days

Free

Window

#3> 120 days

Non-Group

28

Produtos do Grupo 28

- Belt

- Ampligo

- Voliam Targo

- Durivo

- Premio

* Colocar a logomarca dos produtos

Grupo 28

Diamidas

Outro

modo

de ação

Grupo 28

Diamidas

Outro

modo

de ação

30 dias

30 dias

30 d

ias

30 d

ias

IRAC-BR

Grupo 28

Diamidas

3 aplicações

3 aplicações

Produtos do Grupo 28

- Belt

- Ampligo

- Voliam Targo

- Durivo

- Premio

• Colocar a logomarca dos produtos

• Colocar ativo e não marcas

Proposta de selo para o Grupo 28 – Diamidas – IRAC-BR


167

Country reviews

Argentina



Argentina

Diamide Working Group

Buenos Aires, November 23th, 2010

Attendees:

• Ruben Meoni (Bayer).

• Jorge Morre, (DuPont).

•Daniel Ferreras (Syngenta).

We plan for 2011 to prepare a brochure

with our IRM recomendation for group 28

products.



Agenda

Argentina Diamide Working Group

• Read Casafe reccomendation for the Resistance to Group 28.

• Add new labels if there are new submisions.

• Schedule next meeting.



Cultivo Plaga Dosis

(ml/Ha)

Momento de aplicación

SOJA Oruga de las

leguminosas(Anticarsia

gemmatalis)

Isoca Medidora(Rachiplusia nu)

Isoca Militar T. (Spodoptera

frugiperda)

25 – 30 ml/Ha PC

(5-6 g ia/Ha)

Dosificar de acuerdo al

desarrollo del cultivo y grado

de infestación.

Antes de floración:

Desde 15 orugas > 1,5cm por

metro de surco y más de 20 %

de defoliación.

Desde floración:

Desde 10 orugas >1,5 cm por

metro lineal de surco y más de

10 % de daño al follaje.

Label Review: Coragen®




Label Review: Voliam Targo


CULTIVO PLAGAS DOSISMOMENTO DE APLICACIÓN Y

RECOMENDACIONES

SOJA

Arañuela roja común

(Tetranychus urticae)

70-100 cm3/ha (**)

Aplicar al inicio de infestación,

cuando se encuentren 5 ninfas por

hoja trifoliada. Utilizar con una

incidencia menor al 50 % de hojas

con presencia de la plaga.

Oruga de las leguminosas (Anticarsia gemmatalis)

Oruga medidora (Rachiplusia nu)

Aplicar cuando se encuentren 10

larvas pequeñas por metro lineal.

Recurrir a la dosis mayor con alta

presión de orugas y cuando existe

riesgo de reinfestación.

Trips(Caliothrips phaseoli)

Aplicar al detectar un promedio de5 ninfas por folíolo.

En al caso de Trips y Arañuelas aplicar con Aceite mineral Syngenta 500cc/ha.

Respetar las recomendaciones de umbrales de defoliación de cada zona oficiales



Label Review: Ampligo


CULTIVO PLAGAS DOSIS MOMENTO DE APLICACIÓN

SOJA

Oruga de las leguminosas (Anticarsia gemmatalis)

Oruga medidora (Rachiplusia nu)

30-40 cm3/ha

Aplicar cuando se encuentren 10

larvas pequeñas por metro lineal.

Recurrir a la dosis mayor con alta

presión de orugas y cuando existe

riesgo de reinfestación.



Label Review: Belt (draft)




min max

Coragen

Clorantraniliprole

Voliam Targo

Clorantraniliprole+abamectina

Ampligo

Clorantraniliprole+lambdacial

Belt SC

Flubendiamida

PRODUCTO

21 15

Dosis

g G28 ai/haMax n°

aplicaciones

5 6 2 12

3.15 4.5 2 9 21

PHI

(días)

15

14 15

21 30

Dosis Maxima

por

Temporada

Intervalo entre

aplicaciones

(días)

2 57.6

2 83 4

14,4 28.8

Label Review: Comparative Analysis soybean.


Completar


Estrategia de “Alternancia de Ventanas” (Versión 1)

V1........................................Vn R1.......................................................R8


Ventana

Activa(30-40 ds)

Ventana

Inactiva(30-40 ds)

Ventana

Activa(30-40 ds)

Rotational Schemes:



Estrategia de “Alternancia de Ventanas” (Versión 2)

V1........................................Vn R1.......................................................R8


Ventana

Activa(30-40 ds)

Ventana

Inactiva(30-40 ds)

Rotational Schemes:

Ventana

Inactiva(30-40 ds)




Prevención del Manejo Resistencia

En cualquier población de insectos pueden existir individuos naturalmenteresistentes a Diamidas antranilicas u otros insecticidas, producto de la variabilidadgenética normal. Estos individuos pueden eventualmente tornarse dominantes en lapoblación de insectos si se usan repetida y reiteradamente los mismos insecticidas,reduciendo así sistemáticamente la efectividad de los tratamientos.

Diamidas antranilicas pertenece al Grupo 28 de la clasificación de modos de acciónde insecticidas de IRAC.

El uso repetido de Diamidas antranilicas, ya sea solo o en mezclas con otros

principios activos puede favorecer la selección de los individuos naturalmente

resistentes.

Text for communications in “labels”


GRUPO 28 INSECTICIDA



Para evitar la proliferación de tales biotipos resistentes pueden emplearse

las siguientes estrategias de manejo de resistencia.

El uso de insecticidas debe realizarse en el contexto de un programa de

Manejo Integrado de Plagas (MIP), contemplando el monitoreo y observancia

de umbrales, control biológico, técnicas de confusión sexual, etc.

Rotar el uso de Diamidas antranilicas (o cualquier otro producto

perteneciente al Grupo 28 de insecticidas Diamidas antranilicas ) con

productos de diferentes modos de acción para controlar la misma plaga en

generaciones sucesivas.

No realizar más de 2 aplicaciones de Diamidas antranilicas o cualquier otro

producto del mismo modo de acción (grupo 28 de IRAC) por generación de

una misma plaga. Aplicaciones a la próxima generación, independientemente

del cultivo en que esta ocurra, deben realizarse con un producto de diferente

modo de acción.

Text for communications in “labels” (cont.)




Cuando no sea posible determinar las generaciones de las plagas con

precisión, no realizar más de 2 aplicaciones en un período de 30-40 días

(ventana activa). En las aplicación siguientes a ese período rotar con

productos de diferente modo de acción (ventana inactiva).

Contactar los organismos técnicos especializados (INTA) y de extensión

locales de cada zona.

Información adicional sobre prevención de resistencias a insecticidas en

insectos puede encontrarse en www.irac-online.org (Comité de Acción sobre

Resistencias a Insecticidas)





Discuss new crops to be registered:

Dupont: Soja 2 ampliaciones (Helicoverpa gelotopoeon y Pseudoplusia)

Girasol: Rachiplusia nu.

Maiz: Spodoptera.

Tomate?

Syngenta: Tomate. Mosca Blanca y Tuta.

Colza: Plutella.

Mani:

Algodón: Alabama y Heliothis.

Bayer: Soja: Rachiplusia y Anticarsia.

Tabaco: Agrotis y Heliothis

Poroto: Pseudolusia y Rachiplusia





En Argentina está formado el Grupo IRAC referido al grupo Diamidas (grupo 28)

que tiene como objetivo prevenir y demorar la aparición de resistencia a esta

familia de insecticidas, para mantenerlo en el tiempo como una efectiva

herramienta de control de plagas.

Las empresas participantes trabajan en el desarrollo de una guía de uso que

facilite el cumplimiento de los objetivos del Grupo IRAC, promoviendo la

implementación de programas de control integrados de plagas analizando el

riesgo de resistencia, alineando las recomendaciones de uso y desarrollando

programas de control para los cultivos involucrados en el registro y uso de esta

familia de insecticidas.

Ressitance recomendation. Casafe.




Armar folleto para próxima reunión. Consensuar entre las empresas y luego enviar

a externos. Tenerlo listo para la próxima reunión.

Daniel Ferreras enviara propuesta.

Pendiente:




Meetings schedule

2009 meetings:

Feb 27, Syngenta Offices √

May 5, 2009 Bayer Office √

Nov 25, 2009 DuPont Office √

2010 meeting dates and locations

May 27, 2010 (face to face meeting with ext. consultants) √

Nov 23, 2010 Syngenta Offices √

2011 meeting dates and locations.

May 27, 2011

Nov 21, 2011

Committee President for 2011:

Bayer (Meoni Ruben).


Pathforwards



184

Country reviews

USA


2011 International IRAC MeetingBrussels Belgium

March 28

Diamide WG Country Reports

USA

USA Diamide WG Update

Major Milestones

1. Date group was formed: 2009

2. List of Members:

# Country Name Company EmailGlobal Liaison

13 USA

Caydee Savinelli Syngenta

[email protected]

John Andaloro

13 USA Ralph Bagwell Bayer [email protected]

13 USA Dan Sherrod DuPont

[email protected]

13 USA James Adams

Nichino America [email protected]

Target crops: brassicae, lettuce, tomato, cucs, apples







USA Diamide WG Update

Major Milestones

3. How many meetings has the group had to date (F2F vs. audios) - Numerous audios in 2010 to plan Diamide IRM workshop at ESA mtg - San Diego

- F2F in San Diego at ESA meeting with 12 Univ experts and 12 company reps to

initiate plan for experts to develop regional Diamide IRM strategies

4. What are the prioritized crop markets and high risk insects the

group has elected to work on initially:

- BAW - leafy veg/fruiting veg

- DBM – crucifers

- FAW – sweet corn

5. Country Group Update by Crop Market (relative to the Diamide IRM

Country guidelines):

- Step VII: Plan to Develop IRM Guidelines by Crop

IRM Strategies for: Lettuce, Crucifers, Sweet Corn - USA1. What diamide active ingredients are already registered?

- Chlorantraniliprole and Flubendiamide

2. Share electronic versions of labels for currently available diamide products. Show

IRM language for each of the labels, review harmonization of IRM label language or

progress being made to achieve harmonization.

- Need all solo and premix product labels

- Coragen®, Belt®, Synapse®, Vetica®, Turismo®, Durivo®, Voliam Flexi®, Voliam

Xpress®

3. Share final IRM communication document with written IRM recommendations tailored

for Lettuce. Please share growth stage diagrams (crop and pest phenology) showing

the recommendations.

- see following pages for draft examples of different IRM strategies




- These strategies have not yet been completed. They are in the final stages of review

but still require additional editing and alignment from committee and expert

members.

Risk of resistance development and actions

1. Has any reduction of diamide efficacy been observed? - none reported nor obvious

2. Where do you see the major risk of resistance development and why? crop, practices? - DBM in SE US where growers traditionally disregard IRM; grow crucifer

crops continuously - FAW in SE US where there is heavy insect pressure in Spring and Fall and

large number of applications are made

- BAW in SW US on leafy vegetables where multiple plantings/year occur, diamides are used on adjoining crops (alfalfa, cotton, melons), and with an insect (BAW) that has shown wide variation in response to diamide baseline testing.

3. What actions within your country/market would have the greatest impact on encouraging growers to adopt IRM practices for diamides? - strong leadership from local extension influencers and experts

- practical IRM strategies that can easily be implemented on a large scale

- alignment and common communication of IRM strategies among field reps from all 4 chemical companies

2011 US Diamide Company

IRM Label Statements

USA Diamide Label Comparison

(Brassica-DBM and Lettuce-BAW)

Guideline

Group 28 Icon (first page) Yes Yes Yes Yes Yes Yes Yes Yes

Group 28 Description in text Yes Yes Yes Yes Yes Yes Yes Yes

Chemical class identified (ex. diamide) Yes No No No No Yes Yes Yes

IRM Language Section Yes Yes Yes Yes Yes Yes Yes Yes

Max ai/season = chlorantraniliprole or

flubendiamide-containing products*Yes No No No No Yes Yes Yes

Max number of

apps/season*

Brassica (DBM) =

Lettuce BAW) =

4 DBM ----- 2 DBM 2 DBM ---- 1 DBM 3-5 DBM 2-3 DBM

4 BAW ----- 3-4 BAW 3 BAW ---- 1 BAW 3-5 BAW 2-3 BAW

Max number of apps or ai/year* 6DBM No No No No No No No

Do not treat season-long Yes Yes Yes Yes Yes Yes Yes Yes

Apply MOA using window approach Yes No No No No Yes Yes Yes

Explanation of window Yes No No No No Yes Yes Yes

Window approach for short-season

multiple cropping No No No No No No No No

Do not expose >50% of crop No No No No No Yes No No

* Not a Global Diamide Guideline

Coragen®

Belt®

Synapse®

Toursimo®

Vetica®

Durivo®

Voliam Xpress

Voliam Flexi®


Group 28 – Diamide Insecticides

RM Recommendations

University of Arizona

Southeast U.S. Universities

University of Hawaii

Bayer, DuPont, Nichino, Syngenta

US Regional Univ Expert Diamide

IRM Draft Recommends


Diamondback Moth in Hawaii

Insecticide Resistance

ManagementRonald Mau

Emeritus Professor

University of Hawaii

[email protected]

Up to 52 (back to

back) crops / year

No fallow (non-crop)

periods on most

farms

ET‟s are surpassed

almost every week

DBM Resistance in Hawaii

• Organochlorine

• Organophosphate

• Carbamate

• Synthetic pyrethroids

• Bacillus thuringiensis

• Spinosad/Spinetoram

• Indoxacarb

• Novaluron

Farms at Kula, Maui

Shared DBM Population

Field1 Field 4 Field 5Field 3Field 2

Effect of strip cropping and

adjacent farms on DBM population.

Diamondback moth population

Spray here Even if you are only treating one

field, you are exposing the DBM

population to the pesticide.

Possibility for exposure to every generation all year long

Roots of Hawaii RM Program

• Inability to control DBM 1996-1999

• Rapid selection of R to spinosad in 2000

• Dow AgroSciences & IRAC support to

develop a program

Resistance Management Program

• IPM practices

• Dose mortality assay of introduced DBM products

– Lowest calculated 100% kill dose by probit analysis

• Rotation by IRAC classes

– Label determines crop & annual number of applications

• Month-long windows

– Highly effective class products alternated with a less effective class products

Hawaii DBM RM-Team

Veg Agent

Oahu

Veg Agent

Maui

Veg Agent

Hawaii

Ext Entomologist

Grad Student

AgChem

Sales

Farmer

Groups

Farmer

Groups

AgChem

Sales

Manufacturer

Tech and Sales Reps

DBM pupae (week prior to full moon)

Overnight shipment to lab

Collect eggs on paper towels

Hatch on and rear on rape plant

Extension agent performs leaf dip

assay (2L) and reports results

Coordinate assay date

Leaf Dip Assay

Low Kula (F1) discriminating dose bioassay

8/10/2010

IRAC# Brand name Chemical DD (PPM)

28 Synapse Flubendiamide 1.68

5 Radiant Spinosyn 1.08

15 Rimon Novaluron 75

22 Avaunt Indoxacarb 50

6 Proclaim Emamectin

benzoate

1

Check water

Rotation Partners

• (6) Emamectin benzoate

• (28) fendiamide/

chlorantraniliprole

• (23) Spirotetramat

• (5) Spinosad/ spinetoram

• (15) Novaluron

• (22) Indoxacarb

• (11) B. thuringiensis

– kurstaki

– Aizawai

• (2A) Endosulfan

• (1B) naled

• (1A) methomyl

2009 2010 2011 Formulations

Group 5 2 3 2 Radiant, Success, Entrust

Group 22A 3 2 2 Avaunt

Group 15 2 2 2 Rimon

Group 6 3 2 2 Proclaim

Group 28 2 3 3 Synapse, Coragen, Vetica

Group4A 0 0 1 Venom

Hawaii Island

Maui 2010

Month

Product IRAC Code

January Rimon 15

February Bt, Radiant, Entrust 11 & 5

March Synapse, Coragen, Vetica,

Volium Express,

28

April Avaunt, Movento 22A, 23

May Proclaim 6

June Rimon, Thionex, Lannate,

Naled, Movento

15, 2A, 1A, 1B, 23

July Bt, Radiant 11 & 5

August Synapse, Coragen, Vetica,

Volium Express,

28

September Avaunt, Bt 22A, 11

October Proclaim 6

November Rimon, Movento 15, 23

December Bt, Radiant, Entrust 11, 5

Summary

• Active partnerships are needed

• Plan for resistance to new products– Establish baseline toxicity to DBM for each new

product/ group

– Detection of increases in tolerance can possibly allow for remediation

• Regional-based IRM Windows

• Population assay to monitor changes

• Product stewardship by ALL growers– Follow the product labels

Change from Complete Coverage

To

High Concentration and Coverage

(max 60 GPA)


215

Beet Armyworm – Lettuce - General




216



Alternatives for Lep Larvae Control by Crop Stages

Soil –at

plant

Stand

establishment Thinning to Heading Heading to Harvest

InsecticideIRAC MOA

Coty-1 leaf

2-4 leaf

5-8 leaf

9-15 leaf

15-20 leaf

Pre -head

Early heading

2-4" head4-6" head

Radiant 5

Proclaim 6

Intrepid 18

Avaunt 22A

Coragen 28

Durivo 28+4A

VoliamXpress 28+3

Voliam Flexi 28+4A

Synapse 28

Vetica 28+16

Lannate 1A

Orthene 1B

Endosulfan 2A

Pyrethroids 3

Bt 11B

UA IPM Guidelines for Lep Management in Leafy Vegetables

*** Minimum of 4 effective MOA Effectives at any crop stage





Apply insecticides only when needed. Time insecticide applications based

on UA recommended action thresholds (http://ag.arizona.edu/crop/) .

Ideally, the management strategy that presents the lowest risk to

insecticide resistance is one where consecutive applications of the same

product/MOA are not made in the same lettuce field.

This can be achieved by rotating to an alternative product/MOA on each

subsequent spray application to eliminate consecutive uses of the same

MOA (see examples in Figure 3-5 below). Whenever possible, consider

using any single product/MOA only once per lettuce field per crop season.

In lettuce fields where a product/MOA is required more than once, limit

the total usage of that product/MOA to 2 applications per field per crop

season. (i.e., no more than 2 uses of any IRAC MOA or insecticide with the

same color code), and avoid using it on consecutive applications.

4





Use only recommended products and rates necessary to accomplish

desired control (Fig 1 and 2).

Do not apply any active ingredient below labeled rates as this may result in

poor product performance, unacceptable insect damage and an increased

risk of resistance.

Apply insecticides by directed ground sprays to optimize spray deposition

and coverage whenever possible.

Do not apply tank-mixtures containing 2 or more of the newer chemistries

(IRAC Groups - 5, 6, 18, 22 and 28) when controlling lepidopterous larvae.

Not only is this expensive, but generally not necessary based on past

performance trials (Fig 1).

5



Beet Armyworm – Lettuce - Diamide


The Diamide products (IRAC Group 28) offer flexibility in application; they can be

applied to plant foliage translaminarly through foliar sprays, or systemically via soil

applications.

If a Diamide product is applied as a foliar spray, consider using this MOA only once

per lettuce field per crop season. If a Diamide spray is required more than once,

limit the total usage to 2 foliar spray per field and do not use them in consecutive

applications (Figure 3).

Do not apply a foliar Diamide spray prior to or following the use of a soil application

of chlorantraniliprole (Figure 4 and 5).

If a Diamide product is soil applied prior-to or at-planting, as an in-furrow spray or

shank injection, do not spray a Diamide product on that crop at any time during

the remainder of the crop season (Figure 4).

If a Diamide product (IRAC Group 28) is applied as a post-emergence treatment

through drip irrigation, do not spray any Diamide products on that crop prior to the

Diamide chemigation, or at any time thereafter during the crop season. (Figure 5)

6





Do not apply more than 1 application of a Diamide product to the soil regardless if

chemigated through drip irrigation or soil applied at planting. If additional beet

armyworm control is needed during the crop season, use a non-Diamide foliar

alternative. See Figures 1 and 2 for alternatives products/MOA.

Consider using an adjuvant with foliar Diamide applications to assist in spray

atomization and penetration, and to provide uniform deposition of spray droplets

on foliage; this is particularly important in cole crops.

In areas where alfalfa is grown in proximity to lettuce, do not apply any Diamide

product (Coragen, Voliam Xpress) in alfalfa at any time.

In areas where cotton is grown in proximity to lettuce, do not apply any Diamide

product (Coragen) in cotton at any time.

Do not use any Diamide product (soil or foliar) on nursery grown plants destined for

field transplanting.

7



221



Figure 3

Figure 4 Figure 5




Vegetables

Use good IPM practices to minimize reliance on insecticides.

Use of all efficacious insecticide groups with differing modes of action (MOAs) in a

rotation program is strongly encouraged. Where possible, consider using any single

MOA only once per crop season.

Do not rely on Group 28 insecticides for season long protection in any crop. Foliar

applications should use proper rotations of MOAs as discussed below. If a single soil

application of a systemic Group 28 insecticide provides control for more than half of

the crop cycle, do not use Group 28 insecticides in the subsequent crop (rotation of

insecticides between crop cycles).

Use of pre-mixed insecticides, or tank mixtures, should be limited to situations

where both insecticide active ingredients are needed. Do not apply multiple

insecticide active ingredients, with multiple MOAs, unless the pest complex present

(or anticipated) makes this necessary. When this does occur, resistance

management and insecticide rotations must account for both MOAs. Use of either

MOA in one generation or use window would restrict use of tank mixes or pre-mixes

in the next generation or use window. Use of a tank mix or pre-mix would restrict

use of both MOAs, singly or in combination, in the successive generation or use

window. 9




Vegetables

Soil applications:

Limit use of systemic soil applications of Group 28 insecticides to a single

application per season, irrespective of crop or target pest(s).

If a soil application of a systemic Group 28 insecticide is used, do not use foliar

applications of Group 28 insecticides in the same crop, either before or after the

soil application. This is of particular importance in short season crops (less than 60

days).

In longer season crops (greater than 60 days), with pests of moderate to low

resistance potential (e.g. corn earworm), use of a soil application may be followed

by foliar applications later in the crop cycle. However, soil applications of Group 28

insecticides should be followed by at least two applications of effective insecticides

with alternative MOAs after the residual control of the soil application has

diminished. It is strongly preferred that adequate time is allowed after residual

control of the soil application has diminished to allow for at least one generation of

the targeted pest before foliar applications of Group 28 insecticides are used (thus,

assuming a soil application lasts 30 days and the insect has a 28 day generation

time, 58 days should pass between the soil application and the first foliar

application).10




Vegetables

Foliar applications and insecticide rotations:

Where permitted by the label, consider using an adjuvant with foliar Group 28

applications to assist in spray deposition and penetration.

Rotation of foliar applications should use all effective insecticide groups with

different MOAs. Preferred rotation plans base the timing of rotations on the life

cycle or generation time of the pest. Where distinct generations do not occur, the

generation time should be used for rotation timing (length of use windows are equal

to the generation time of the pest of concern). Insecticides with similar MOAs

should not be used on successive generations (or within successive use windows).

Within a generation (or use window), a single MOA should not be used more than

twice (preferably once) and should not be used during the next generation (or use

window).

11




Vegetables

Foliar applications and insecticide rotations:

No more than two (preferably one) Group 28 use windows should be used within a

crop. This may consist of a soil use followed by foliar use (in long season crops), or

two foliar use windows. Non-use windows should be the length of residual control

PLUS the generation time of the pest. The Group 28 use windows should be

separated by at least one generation/window of alternate MOA use. If insecticide

use is not required during a non-Group 28 window (between two Group 28 use

windows) then alternative MOAs should still be used prior to Group 28 use

(irrespective of time frame, two Group 28 use windows should be separated by use

of efficacious alternate MOA insecticides).

(I cannot think of a case where this applies to vegetable production in the

southeast, but I had the thought and wanted to write it down). If targeting a pest

with distinct generations, successive generations should not be exposed to selection

by a Group 28 insecticide. This includes residual control. Thus, use during a

generation should occur early enough within that generation to allow for residual

control to decline prior to the subsequent generation.

12



226


Vegetables

EXAMPLES (assumes a 30 day residual for soil application and a 30 day pest generation time; actual timing should be adjusted for actua l residual

control and generation time of the specific pest).

Short season crop – single pest – generation time of 30 days (overlapping generations):

Crop cycle (days since planting) Notes

0-10 10 - 20 20 - 30 30 - 40 40 - 50

Option I - Soil app at planting

Soil Group-28(30 days of residual control)

G-28 not allowed Group 28 not allowed in next crop if sequentially planted

Option 2 – Soil app delayed

G-28 not allowed Soil G-28 applied day 20(30 days of residual control)

Option 3 – foliar app Maximum of 2 apps of G-28 during a 30 day window (window may occur at any time in the

season)

If Group 28 is used at the end of the season, subsequent sequentially planted crops should extend non-use to 30 days.

Note: Soil and foliar applications should NOT be combined in short season crops.



227


Vegetables



90 day crop – single pest – generation time of 30 days (overlapping generations)

Crop cycle (days since planting)

0 – 10 10 - 20 20 - 30 30 - 40 40 - 50 50 - 60 60 – 70 70 - 80 80 - 90

Option 1 – soil app at planting

Soil G-28 at planting(30 days residual control)

One generation of no G-28 Use alternate MOAs

Maximum of 2 G-28 foliar apps

G-28 use windows can be shifted, but must be separated by a full generation time after residual control has declined and must include alternative MOA use.

If insecticide use is not required during the alternate window then alternate MOAs should be used first in second G-28 window.

Option 2 – soil app delayed

No G-28s Soil G-28 applied day 20(30 days residual control)

No – G-28s Foliar G-28

With soil applications, first foliar applications are not allowed until roughly 60 days after soil application (assumes 30 days residual control + 30 days for non-selected generation). An alternative MOA must be used prior to foliar application of a Group 28 insecticide.

Option 3 – foliar appEarly use

Max of 2 G-28 apps.(residual gone by day 30)


Max of 2 G-28 apps.


Option 4 – foliar appDelayed use

No G-28 use



Max of 2 G-28 apps.



228


Vegetables



90 day crop – single pest – generation time of 30 days (overlapping generations)

Crop cycle (days since planting)

0 – 10 10 - 20 20 - 30 30 - 40 40 - 50 50 - 60 60 – 70 70 - 80 80 - 90

Option 1 – soil app at planting

Soil G-28 at planting(30 days residual control)


Maximum of 2 G-28 foliar apps

G-28 use windows can be shifted, but must be separated by a full generation time after residual control has declined and must include alternative MOA use.

If insecticide use is not required during the alternate window then alternate MOAs should be used first in second G-28 window.

Option 2 – soil app delayed

No G-28s Soil G-28 applied day 20(30 days residual control)

No – G-28s Foliar G-28

With soil applications, first foliar applications are not allowed until roughly 60 days after soil application (assumes 30 days residual control + 30 days for non-selected generation). An alternative MOA must be used prior to foliar application of a Group 28 insecticide.

Option 3 – foliar appEarly use



Max of 2 G-28 apps.


Option 4 – foliar appDelayed use

No G-28 use



Max of 2 G-28 apps.

If the pest of concern has distinct generations, then the use windows are defined by the generation. Thus, with distinct generations, use

windows can NOT be shifted within the crop cycle. Use within a generation should be timed for residual control to decline prior to the next

generation.



229


Vegetables

Short season crop – sequential plantings – potential “area-wide” rotations: (xxx = crop present)

Field Days after planting Field 10-10 10-

2020-30

30-40

40-50

50-60

60-70

70-80

80-90

90-100

100-110

110-120

120-130

130-140

140-150

150-160

160-170

170-180

180-190

1 xxx xxx xxx xxx xxx2 xxx xxx xxx xxx xxx3 xxx xxx xxx xxx xxx4 xxx xxx xxx xxx xxx5 xxx xxx xxx xxx xxx

6 xxx xxx xxx xxx xxx7 xxx xxx xxx xxx xxx xxx8 xxx xxx xxx xxx xxx

Pre-selected calendar window for soil applicationR-1 G-28 anytime No G-28 G-28 anytime No G-28R-2 G-28 No G-28 G-28 No G-28 G-28 No G-28R -3 G-28 No G-28 G-28 No G-28 G-28 No G-28Calendar windows for foliar applicationsR-4 G-28 No G-28 G-28 No G-28 G-28 No G-28

R-5 G-28 No G-28 G-28 No G-28 G-28 No G-28 G-28

R-1 allows soil applications for 30 days followed by none for the 30 days of residual plus 30 days of non-selection (60 days between applications)

R-2 allows soil application first 10 days followed by none for the 30 days of residual plus 30 days of non-selection

R-3 potential grower adjustment of R-2

R-4 allows G-28 use for 20 days (20 days use + 10 days residual= 30 days activity) followed by 40 days non-use (10 days residual + 30 days non-

selection)

R-5 potential grower modification showing use within 10 days (could be 2 applications) followed by 40 days non-use (10 days residual + 30 days

non-selection)



Company Labels

RM Language

Key Considerations

– Advisory statements

• Language reflects advice and not something the States have to

enforce

– General Recommendations – One size does not fit all

230



Company Labels

RM Language

Unless directed otherwise in other parts of the label, the best practices are

In order to maintain susceptibility…

– Avoid using a single MOA for season long control of an insect species with

more than one generation per crop season.

– Use a window treatment rotation for insect species with multiple or

overlapping generations

– • For insect species with successive or overlapping generations, apply

Product X or other Group X insecticides using a “treatment window”

approach. A treatment window is a period of time as defined by the stage

of crop development and/or the biology of the pests of concern. Within

the treatment window, depending on the length of residual activity, there

may either be single or consecutive applications (seed treatment, soil,

foliar) of the Group X insecticides. Do not exceed the maximum Product x

allowed per growing season.

231



Company Labels

RM Language

Following a treatment window of Group X insecticides, rotate to a treatment

window of effective products with a different mode of action before making

additional applications of Group X insecticides.

A treatment window rotation, along with other IPM practices for the crop and

use area, is considered an effective strategy for preventing or delaying a

pest’s ability to develop resistance to this class of chemistry.

If resistance is suspected, do not reapply Product X or other Group X

insecticides.

Other IRM Practices

– Incorporate IPM techniques

– Combine different control mechanisms.

– Monitor treated populations

Additional Information

– Consult local specialist

– Visit IRAC website232



233

Country reviews

Spain


Fenos (flubendiamida 24WG) and Alatcor (Clorantraniliprol 35WG)

Registration in 2010.

Many crops without diamide registration until now. Reg. in process.

Only overlap in solanaceous/ indoor

Ornamental FRUIT VEGS

INDOOR OUTDOOT

Ornamental Solanaceus Cucurbits Others Solanaceus Cucurbits Others

Fenos 15-25 mL/hL 15-25 mL/hL 15-25 mL/hL 15-25 mL/hL

Altacor 10-11,5 mL/hL 10-11,5 mL/hL

LEAF VEGS GRAPE Orchads

OUTDOOT

Lettuce Brassicas Table g. wine Pome fr. Stone fr.

Fenos

Altacor 85-115 g/ha 10 mL/hL

DIAMIDES SPAIN , March 2010

Spain

• Recommendation in the label:

Maximum 2 active windows (1 or 2 back to

back applications) per crop cycle.

Minimum interval between group 28

applications: 60 days

This recommendation is already in both

labels of Fenos and Altacor

DIAMIDES SPAIN , March 2010

Spain


239

Process to Review, Edit, and

Approve Country IRM Proposals


Process to Review, Edit, Approve Country IRM

Strategy Communication Proposals

1. Country mentor submits country IRM communication strategy complete with

phenology chart and rotation IRM plan to the Global Diamide Team

2. The IRAC Global Diamide Team will review and make suggestions. (recommend

additional slides to help influencers better understand….see slides 42 to 47 to add

to your communication) presentation/promotion.

3. Once a final draft is agree… send to IRAC Executive team to approve. THIS IS

CRITICAL...then your strategy will get approval from all the other insecticide

companies beyond those selling Diamides. This means that when you

communicate the Indonesia Diamide Strategy, you can say it is not just from

DuPont, Syngenta, Nihon, and Bayer but from all the companies in International

IRAC (Dow, BASF, FMC, Cheminova...etc.)

4. Mentor sends final version to Country Diamide team.

5. Country mentor follow sup with development of a training plan. How, when, and

who will communicate to influencers and trainers? Send the plan developed by the

Philippines team. This gives a perspective on how to take the next step.

Remember that all our company sales and dev reps are influencers/trainers.


241

Diamide WG: issues, company

objectives and WG accomplishments


Preserving Diamide Chemistry:

One Market at a Time

Update on Issues, Efforts, and

Recommendations to Delay Insect

Resistance to Diamide Products

(Ryanodine Receptor agonists)

Global IRAC Diamide IRM Working Group

March 2011

JTA 3-15-2011



ISSUES

Preserving Diamide ChemistryIssues:

Flubendiamide sold years before other

diamides were in the market In Thailand and

Philippines.

No coordinated IRM effort among diamide companies

prior to initial sales of flubendiamide. Although Global

Diamide Team was started in late 2008 it was not

early enough too be effective for countries with early

registrations.

IRM implementation is at the country market

level….not at the global level

The global diamide working group was initiated in

2008 and took most of the year to develop global

strategies and a plan to use country teams for

implementation. The result….some country diamide

working groups started in 2009 and others in 2010

and need more time to be productive.

Cooperation, motivation, and resistance issues

vary significantly among Intercompany country

diamide teams.

Progress has been slow for some country teams to

incorporate global guidelines into practical strategies

for local high-risk markets due to lack of: leadership,

commitment, understanding expectations, and support

from management.

Success is unlikely in markets were there are

only marginally effective products as rotation

partners; fro example, Thailand and

Philippines, where diamide resistant DBM

occur.

Highly improbable an IRM program can be

implemented, in a reasonable time frame, where

growers with few options are desperate. Success can

be achieved with drastic changes in cropping patterns

requiring time and resources, thus can not be a focus

for diamide companies

Explanation:

Preserving Diamide Chemistry; cont‟dIssues:

There is no restriction on # of total diamide

apps per cropping season nor per year.

In some key markets growers can legally make over

eight applications of different diamide products per

cropping season. Growers don‟t know the products

represent the same chemistry, use reduced rates for

affordability, and have no incentive to rotate.

Continuous monoculture is the most challenging and

where resistance first occurs.

Utilizing regulatory strategies to steward

diamides is slow if label changes are made

post-registration and if country label

language/format rules are not amenable to

objectives of diamide teams

Definitive common IRM label language had been in

transition throughout 2009 and is only in 2010 where

alignment has been made. Existing DuPont and

Bayer labels take time to edit once registration has

occurred. Some EU countries require two years.

Some countries do not allow the “Group 28” icon.

Insufficient time to mobilize troops and

implement plans for a task of this magnitude in

the time needed. Should have started sooner.

An effort of this proportion with the number of players

has not ever been conducted before. Significant time

and effort is necessary to change behaviors, attitudes,

beliefs, habits, labels, regulatory procedures,

competitive relationships. Only the naïve will believe

this can be done in a few years.

Explanation:



COMPANY OBJECTIVES

1.Diamide companies align their labeled

directions for use:

- Work as an industry to add Group 28 MOA icon and IRM

language to country labels. Where necessary, change

conventional thinking of regulators to allow these label additions.

- Change diamide label language that stipulates max number of

applications per season to read as “chlorantraniliprole or

flubendiamide-containing products” and eventually to read as

“Group 28 applications” vs individual product applications.

- For continuously planted crops label a max number of Group

28 applications per crop per year.

Preserving Diamide Chemistry – Possible

Options Available for Intercompany

Cooperation

2. Global and country company

management need to convey support to

their respective team members:

- Participation and time spent on country diamide teams was

not planned. It was thrust upon country personnel.

- Management needs to express level of urgency, and commit

resources to develop and implement strategies.

- Diamide company management need to communicate a

common message to country team members….this is an

industry priority!

Preserving Diamide Chemistry – Possible

Options Available for Intercompany

Cooperation

3. Identify and support actions that will accelerate the progress of

country diamide teams to develop market-specific diamide IRM

strategies, create appropriate communications, conduct internal

and external training, convert influencers and decision makers:

- Time and guidance is required from global company experts

(Global Diamide WG) to guide and train key country diamide

teams to better understand their roles.

- Resources are required at the local level to develop training

materials for knowledge transfer, recruit and gain alignment

from local experts, and educate the distribution channel.

Preserving Diamide Chemistry – Possible Options

Available for Intercompany Cooperation



DIAMIDE IRM WG

ACCOMPLISHMENTS

• Global Diamide Team:

– Initiated IRAC Working Group in 2008 and

have had 26 meetings.

– Published Global Diamide IRM guidelines –

2008-09

– Initiated 17 country diamide teams focused on

transition of global diamide IRM strategies to

key local markets at risk to insect resistance –

2009-2011

– Developed a plan for addressing suspected

field resistance - 2010

Preserving Diamide Chemistry –

Status of Global and Country Diamide Efforts

• Country Diamide Teams:

– Argentina, Spain published IRM recommendations and in process of implementing these actions.

– Philippines and India ready to publish IRM recommendations for key markets and initiate knowledge transfer process.

– Philippines WG acquired $24,000 form IRAC international to conduct in-depth training sessions for influencers (trainers) and growers.

– USA aligning and guiding market experts to implement IRM strategies through national workshops. IRM recommends for different regions are in draft form.

– China, Thailand, Indonesia, Australia, Malaysia, Brazil, Korea, Vietnam, Mexico, and Japan in various stages of understanding and progress

– India, Philippines, China, Thailand, Indonesia, Australia, Spain, and USA have received face to face or very personal training from global members in 2010.

– Italy, Morocco, and Turkey working groups about to be initiated.

Preserving Diamide Chemistry –

Status of Global and Country Diamide Efforts; cont‟d

Benefits of Maintaining Insect Susceptibility

to Diamides

1). Increased Product Longevity:

- more effective products are available for a longer period of time

- growers have more pest control options; increased flexibility in product

selection

2). Growers Save Money:- no need to increase dosage increased to maintain efficacy

- no need to tank mix to control pests

3). More Stable Crop Production:- better assurance of good pest control

- expect more consistent crop protection and stable yields

4). Protection of the Environment:- less active ingredient applied to ecosystem

- more control over spray program and products used; not in survival mode

IRAC Diamide Guidelines To Maintain Insect Susceptibility

1. Avoid repeated and exclusive use of Group 28 insecticides throughout a crop cycle for a pest species with more than one generation. The “Ideal” is not to expose successive pest generations of the same species to the same insecticide mode of action.

2. Position Group 28 Insecticides in Integrated Pest Management and Insecticide Resistance Management Programs

3. Ensure correct use of the Group 28 Insecticide Label. Do not over or under dose.

4. Apply Group 28 Insecticides using a “window‟ approach to avoid exposure of consecutive pest generations to the same mode of action.- Window approach emphasizes a 4 week diamide free window for eggplant and 3 week

diamide free window for cabbage

5. For short cycle crops (< 50 days), consider the duration of the crop cycle as a “Group 28 insecticide treatment window”, thus alternate to different modes of action during subsequent plantings at the same farm location.

6. Do not expose more than 50% of the crop cycle to the same MOA group.

7. Avoid use of Group 28 Insecticides in insecticide mixtures for the same pest

IRAC Executive

Member Companies

http://www.belchim.com/


256

Diamide WG: SMART objectives

2011 / 2012


Insecticide Resistance Action CommitteeInsecticide Resistance Action Committee

Goals Objectives Timeline

I. WG operational process

II. Promote Global Guidelines

a) Updates: how the group will operate

and how work load will be shared

b) Re-define supporting role for

effective progress in country

implementation

a) Continue to develop communications

and educational materials as needed

b) Update Global Guidelines and

continue to use this document as a

reference for development of locally

tailored susceptibility management

programs

c) Continue to create public awareness

of the mission of the Global IRAC

Diamide WG amongst consultants,

PCAs, growers, and regulators

May 2010

Throughout 2010

Events?

June 2010

Throughout 2010

2010 SMART Objectives and Goals





III. Serve as

resources

(Liaisons) for

country working

groups, promote

progress in

developing, refining

and promoting local

IRM guidelines for

30 prioritized crop

markets

a) Continue to expand creation of country working

groups (high risk markets) as needed, help guide

how the group will operate and how work load will

be shared

b) Guide teams on label reviews and incorporation

of proposed standardized IRM language

(inclusion of window concept)

c) Promote development and publication of IRM

Fact Sheets by for specific pests and crops

d) Support development of communication and

educational materials: slide presentations,

posters, brochures, handouts

e) Support local efforts to expand public awareness

of the mission of the country IRAC Diamide WG

amongst consultants, PCAs, growers, and

regulators

f) Select one “case study” country: more active role

Throughout

2010






IV. Publish

standardized

bioassay

methodology

for Group 28

insecticides

V. Agree on

points of

common

interest and

how to

maximize

use of

resources

(budget/

priorities)

a) Continue to develop and publish IRAC-approved bioassay

methods for key insect target species in the order Lepidoptera,

(Tuta absoluta, rice stemborers, rice leaf folders), and

Coleoptera (CPB)

b) Established IRAC-approved bioassay methods for priority

insect target species in order Hemiptera (whiteflies and aphis –

Cyantraniliprole)

c) These methods will be published as IRAC-recommended

methods to be used by the local country WGs

a) Example: Pooled funding for cross-resistance risk assessment

and resistance mechanistic research (Thailand Plutella

xylostella)

b) Example: pooled funding for research to further validate

“window” approach – combine efforts with Lepidopteran WG.

IRAC sponsored project …..LEP WG

c) Educational Efforts …. IRAC

August-

December

2010

December

2010






VI. Development of

Educational and

Promotional Plan

VII. Prepare for quick action in

case of indication of

susceptibility shifts

VIII. Involvement of key

influencers in the area of

IRM

a) List technical meetings for participation

b) List needed educational and promotional

materials

c) Assign tasks and deliver tools

a) Complete legal review and publication of Global

Guidelines document version 2.1 which includes

a the process for mitigation as a guidance tool

for countries to follow (decision tree in case of

suspected resistance development to diamides)

a) Co-organize with US-WG workshop/ Symposium

share crop-based IRM recommendations and

validate if principles adequate? Propose expert

review of global guidelines document

May 2010

July 2010

July 2010

December 2010





Objectives Timeline

1. Review our global IRM guidelines (label language, poster)

2. Start Diamide WGs in Morocco (Andrea), Italy (Andrea), Turkey (Robert),

Taiwan (Robert), Israel (Andrea), South Africa (Luis)

3. Move the existing WGs from planning stage (develop recommendations)

to action stage (implementation of IRM recommendations and

educational plans)

4. Increase participation of Global Diamide WGs in Country WG meetings

5. Improve compliance of the labels with the IRM guidelines

6. Develop ‚drastic„ measures (beyond IRM guidelines) to prevent

resistance and offer them to high risk countries (Robert to make a first

draft)

May 2011

Kick off by

May 2011

Through end

of 2011

2011

2011

2011

2011 SMART Objectives




262

- Sell the products only during some months in the year

- Convince influencers to recommend to stop sales in a region for one year

- Take one region or country as example about what to do in order to prevent

resistance

- Lobby through Crop Life to stop sales for one year in a certain country

- Offer our support to Crop Life in order to take drastic measures against resistance

Brainstorming “Take action against resistance development”



263

Methods update



7 diamide methods listed on IRAC e-methods web-page (+ 4 compared to 2010)

2 Approved5 Under Review+ 1 External Reference

Helicoverpa spp.Heliothis spp.

Spodoptera spp.

Cydia pomonella

Plutella xylostella

Tuta absoluta

Aphis gossypii

Myzus persicae



Summary/ Review Slides

2009/10

• Tuta absoluta video• Filming complete, final editing ongoing.• Narration agreed, but needs to be recorded.• Trial version can be seen on you-tube

• Leptinotarsa decemlineata• Diet method proposed by DuPont• Is current method (007) appropriate, do we need different method ?

• Chilo suppressalis & Cnaphalocrocis medinalis• No current IRAC methodologies for these species• Syngenta and DuPont have proposed methods• Can we combine methods as there is little difference.

• Bemisia tabaci• DuPont proposed method (University of Florida & Cartagena)• Different from previous methods as requires systemic uptake



• Literature review – place on reference list ?

• Lobesia botrana Ioriatti et al (PMS, 2009)• Choristoneura rosaceana Sial, Brunner & Doerr (PB&P, 2011)• Leucinodes orbonalis Latif (JPS, 2010)• Liriomyza trifolii Conroy (JESO, 2008)• Grapholita molesta Jones (JEE, 2010)

• What next ?

• Adoxophyes orana• Mamestra brassicae• Pieris rapae• Ostrinia nubilalis• Leucoptera coffeella• Sucking pests – whitefly, thrips • Videos ?



267

DBM Workshop



268

DBM Workshop



269

DBM Workshop



270

DBM Workshop

IRAC„s booth



271

DBM Workshop

IRAC„s booth



272

DBM Workshop

IRAC„s presentations


Diamide Working Group F2F meeting 2011 - IRAC · - Attached for DuPont and Rallis. Bayer‟s Fame...

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