Cynthia Natiello, ARNP Seattle VA - mtsaacn.org · Tobacco use, SOB or DOE as presenting ......

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Cynthia Natiello, ARNP Seattle VA

Transcript of Cynthia Natiello, ARNP Seattle VA - mtsaacn.org · Tobacco use, SOB or DOE as presenting ......

Cynthia Natiello, ARNPSeattle VA

Coronary Artery Bypass Graft (CABG)

Valve Replacement

MAZE Procedure

TMR

Aortic Aneurysm Repair

Heart Transplant

CAD single or multivessel Significant LM > 50%, widow makerRefractory anginaAngina with injury/ST elevation or

ischemia/ST depression LV dysfunction, proximal LAD LV failure/cardiogenic shock d/t CAD Perforation of coronary artery after PCI

Aorta

Right

Coronary

Artery

(RCA) Left

Anterior

Descending

(LAD)

Circumflex

(Cx)

Left

Main

(LM)

Coronary

Arteries

Cardiac catheterization:Angina, presence or lack of CADDelineates anatomy & targets

Echocardiogram:Murmurs, suspicion of valvular diseaseR or L ventricular dysfunctionEjection fraction 55% nl.

History & physical including social & family

EKG

CXR PA & Lat

Type & Cross x 4 U PRBCs & 6u w/4u FFP if redo

Labs:

-CBC, coags, chemistry, BNP

-Urinalysis

-LFTs Anesthesiologist Consults with specialty teams

Carotid Duplex:

Age > 65, PVD, TIA/CVA, presence of carotid bruit

Pulmonary Function Tests:

Tobacco use, SOB or DOE as presenting symptoms, exam findings, pulmonary disease

DENTAL

Clearance for valve or graft placement

(e.g. aortic aneurysm repair)

Rationale: Oral disease can cause

endocarditis of a new valve (a catastrophic p/op situation)

BETA BLOCKERSImportant! Should be continued

ACEI/ARBSDC 1-2 days pre-op, peri-operative hypotension

WARFARIN

DC 5 days pre-op, bridge w/LMWH, bleeding

PLAVIX

DC 5-7 days prior, bleeding

ASPIRIN continue

INSULIN & METFORMINHold am dose, NPO & hypoglycemia

STATINS continue

ANTIBIOTICSCefazolin 1-2 gm & Vancomycin 1 gm

CHLORHEXIDINE SCRUB/MUPIROCIN

Median

Sternotomy

Endovascular Vein Harvesting

Coronary Artery Bypass Graft Surgery (CABG)

Purpose: Decreases O2 demand

Surgical Indications:

Pre or post/op MI, weaning from CPB,

maintenance of graft patency

Contraindications:

Aortic regurgitation, thoracic & abdominal aortic aneurysm, severe PVD, bleeding

Preload- degree of myocardial stretch created by venous return , the load placed on the cardiac muscles before contraction. For the ventricles, the amount of volume at the end of diastole 4-12mmHg.

Afterload-the force that opposes ventricular ejection & resistance of the arterioles,

Inflation:

Increases coronary blood flowIncreases diastolic pressureIncreases systemic perfusion

Deflation:

Decreases after load

IVC phase shortenedIncreases stroke volumeEnhances cardiac output

Internal Heart Anatomy

Indications:Stenosis-narrow valve or unable to open fully

Insufficiency-too wide and unable to close completely

S/S: AS-DOE/SOB, syncopeAI-fatigue, dyspnea, dizzinessMVP-asymptomatic, chest pain MR-tachycardia, dyspnea, orthopnea

Bioprosthetic Valve

Prosthetic

Insertion of Mitral Valve Ring

Bioprosthetic/Porcine

Aortic INR none, ASA 81mg

Mitral INR 2.0-3.0, x 3 mo., 81mg ASA

Prosthetic/Mechanical-chronic

Aortic INR 2-0-3.0, ASA 81mgMitral INR 2.5-3.5, ASA 81mg

ACCP Evidence based clinical practice guidelines, 8th

ed. 2008

Treats AF

Laser treatment for AF, creates a maze of new electrical pathways so that impulsescan travel easily through the heart.

P/op complications: Bradycardia-permanent pacemaker, bleeding

Anticoagulation for 3 months

Treats refractory unstable angina

CO2 laser drills holes in epicardial wall

at rest

Increases oxygenated blood flow &

stimulates new blood vessel growth

Alpha receptors:Vascular smooth muscle, alpha 1 vaso-

constriction (pressor effect), alpha 2 dilatation, NE > Epi

Beta receptors:Beta 1 heart, increases rate & force of

contraction (inotrope effect), NE = EpiBeta 2, vascular smooth muscle, dilatation,

Epi > NE

Norepinephrine (Levophed)

Sympathometic w/largely alpha 1-increasing SVR & BP, .01-.1 mcg/min, little beta 1-increasing contractility & pulse

Epinephrine

Strong beta 1 contractility-increasing CO & pulse, .01-.3 mcg/kg/min, low doses beta 2-dilatation, high doses alpha 1-increasing vasoconstriction & BP

Vasopressin

Potent vasoconstrictor, increases SVR & BP, .01-.1unit/min

Milrinone

Increases CI & contractility, decreases SVR, 0.25-0.75mcg/kg/min

Dopamine

Increases contractility, C.O., SVR & P, .5-20mcg/kg/min

Dobutamine

Increases contractility, CO & mild increase in SVR, 2-15 mcg/kg/min,

NTG

Smooth muscle relaxant, low doses, 5-200 mcg/min,), reduces preload, higher doses reduces afterload, used after CABG to prevent LIMA vasospasm, decreases BP

Nitroprusside

Decreases SVR, reduces afterload, increases BP, .3-5mcg/kg/min

Insulin Serum glucose 100-140 mg/dL

w/continuous infusionDiabetic & non-diabeticContinue 72 hrs or until taking PO, then

SQDecreases mortality & morbidityDecreases p/op infections

Amiodarone…

Systolic blood pressure (SBP) 60-90mmHg

Cardiac Index (CI) 2.2-4.4L/min

Central Venous Pressure (CVP) 10-15mmHg

Pulmonary capillary wedge pressure (PCWP) 10-15mmHg

Systemic Vascular Resistance (SVR) 800-1200

Mean Arterial Pressure (MAP) 70-100mmHg

Cardiac Output (CO) 4-8L/min

Air, fluid or blood from pleural space

H2O seal chamber-nl rise & fall w/respiration, air leak w/persistent bubbling, ok w/coughing

Cessation of drainage-clotted, kinked

Pain @ insertion site w/inspiration-improperly placed, interferes w/deep breathing

Assess for SQ air & s/s infection

Bloody drainage > than or equal to 200ml/hr, hemorrhage/shock

Epicardial Pacing Wires

Monitor for dysrhythmias

Separate & insulate grounding pins

Gloves when manipulating or cleaningwires

No electric shavers Shower after wires are removedRemoval in supine, steady slow gentle

tension uncoils wire, 24h before DCMonitor for S/S of cardiac tamponade, rare

Arrhythmias

Bleeding/HIT

Cardiac tamponade

Hypothermia

Pulmonary

complications

Cardiogenic shock

Hypo/hypertension Renal dysfunction Infection CNS complications GI complications Hyperglycemia/DM Electrolyte

imbalance

Afib-common, 20-30% cardiac surgeries, > 50% valve surgery, older pts, atrial arrhythmias, lung disease, R CAD, long cross clamp time, hypothermia

Ventricular-less common 1%, hypoxemia, acid-base imbalance, acute MI

Heart blocks-valve & MAZE

Treatments:Correct K+ and Mg++, medications,temporary pacing

Atrial Fibrillation Increases risk of p/op ventricular arrhythmias

Treat prophylactically:Metoprolol 25-50 mg PO bidMagnesium 2 gm IV after CPB & POD #1Amiodarone started in OR & converted

to PO 150 mg, then 60mg/h x 8 hrs, then 30mg/h x 16h then 400 mg PO bid x 1 week

Causes:Heparin intra-op, long case, redo surgery, p/o anticoagulation

Treatments:Blood products, IVF, medications, apply PEEP, re-explore chest 1-3%

Type 1

Common w/i 48 hrs, PLT ct 100.00

Type 2

PLT decrease by 50% 5-10d

Treatment

Stop heparin, start IV lepirudin or argatroban

Precordial fullness, pain, dyspnea, anxiety,

cyanosis, altered LOC, feeling of

impending doom

Beck’s triad: hypotension, distended neck

veins, muffled heart tones

Falling UOP

Tachycardia to PEA

Hemodynamic changes:

High equalizing pressures RA, PCW, LA

Narrowing pulse pressure

Fall in CI

CXR shows widening mediastinum

Tranesophageal echo

Widening of

mediastinum

Kouchoukos, N T Aneurysms of the Ascending Aorta,

pg227 In Glenn’s Thoracic and Cardiovascular Surgery

Diagnosis: CXR

Treatment

Declot chest tube

Volume-NS, Albumin, blood products

Pericardiocentesis

Open chest @ bedside

Return to OR

<36 C to ICU

Increases SVR & BP, atrial & ventricular

arrhythmias, shivering decreases O2 &

increases CO2, Plt dysfunction

Nitroprusside & propofol for vasodilatation

Apply body warming air blankets-BAIR Hugger

Common:

Pleural effusion

Pneumonia

HF

Pneumothorax

Less common:

PE

Hemothorax

Paralyzed diaphragm-phrenic nerve

Hemidiaphragm elevation

Prevention:

Early extubation, pharyngeal dysfunction from prolonged intubation-risk for aspiration pneumonia d/t dysphagia

Adequate pain medicationsPulmonary toiletingOOB w/i 12 hrs p/opMaintain CT patency & remove asapDiuresis decreases effusions, start POD

#2

Perioperative AMI is uncommon, 5%

Observations:

Assess for decreased SVR & CI/CO

Observe for ECG changes

Cardiac enzymes

Decreasing UOP, classic sign

Treatments:

Vasoactive drugs for coronary spasms

Increase filling pressures, maintain CO

If p/op AMI, return to cath lab/OR

Causes:

Pain

Anxiety

Chronic issue

Volume overload

Treatments:

Pain medications

Anxiolytics

Antihypertensive

Diuretics

Cause:

3rd spacing

Volume depletion, diuretics

Inadequate fluid intake

BB to prevent AF

Tamponade

Shock: hypovolemic, cardiogenic, septic

Treat cause

Common causes:

Pre-existing disease-CKD

Pre-op medications, ACEI/ARBs & NSAIDS

Hypotension

Cardiac catheterization dye load

P/op vasoactive meds, NE, vasopressin

Prevention/observations:

Maintain cardiac index( CI) >2.2 & MAP> 65 mm Hg

Use as little vasoactive medications aspossible

Monitor BUN, creatinineAvoid anti-inflammatories, toradolDialysis

Common Cause: Underlying lung disease, diabetes, catheters in prolonged time, poor protoplasm

Treat:Blood sugar control <140-180 mg/dLMinimal wound manipulation: remove surgical dressing 2 days, transparent occlusive dressing on graft site @ DC

Excellent hand washingMonitor incisions, WBC, temp…Blood, wound & sputum cultures, UA, Antibiotics after culture if possible

Mediastinum:

Loosely defined space between the L & R pleura, sternum & vertebrae; contains heart, great vessels, esophagus & loosely organized connective tissues

Mediastinitis: deep infection requiring surgical debridement &/or surgical repair (retrospective dx)

Systemic symptoms precede local

Fever, leukocytosis, tachycardia, general illness

Pain &/or sternal instability

Crepitus on exam

Purulent drainage &/or local cellulitis

Median detection POD #7, majority w/i 14 days, rare beyond POD #30

MSSA linked to pre operative skin flora

MRSA linked to true patient to patient transmission (nosocomial)

Treat w/antibiotics or surgical debridement

Causes:Micro-emboli, aorta, most commonCerebral hypoperfusionCarotid stenosis

Assess LOC/Neuro as soon as able

Head CT/MRI

Neurology consult

Dysphagia-ice chips, speech consult

Nausea-zofran

Constipation-colace, supp, increased activity, PT/OT

Diarrhea-stool specimen, fluids

Gastritis/GI bleed-PPIs, H2 blockers, antacids

ileus-bowel rest, NGT, TPN

Emergent bowel exploration

Causes:

Pre-existing dementia, medications, pre-op anxiety/paranoia

Treatments:Re-orientRemove restraints ASAPMaximize sleeping patternsControl environmental noiseAssess/control pain-watch for hallucinationsEliminate medication offenders-narcoticsPrevent sternal injuries

IS x 10 q 1h Sternal precautions pt/familyOOB for meals & ambulate 3-4 X/day Shower if CT & pacing wires out

Monitor:Labs: Hct, WBC, PLT, Cr, K+, PT/INRDaily weight so important! S/S InfectionPain controlMedication effects

Saphenous: ACE, occlusive dsg, no SCDs

Radial: No blood pressure or lab draws from

arm, assess hand function, exercises

Monitor:

Hematoma, cellulitis, purulent drainage,

compartmental syndrome

Evaluate peripheral circulation:

aortic dissection, emboli

Evaluate renal function-malposition of catheter

Identify best augmentation, 1:1…

Observe for bleeding, Plt trauma

Monitor for arrhythmias

Monitor for infection

Pt. comfort

Protect IABP placement: skin, log rolling,

avoid leg flexion, HOB < 30 degrees

Sternal precautions-no lifting, pushing,

pulling >10lbs or driving for 6 wks

Daily walking

IS q2h x10 for 1 wk

BP, P, T

S/S infection

Incision care-no hot tubs, swimming

pools, jacuzzis

F/up Cardiac sx, Cardiologist, PCP

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Aasbo, J.D., Lawrence, A.T., et al. “Amidarone prophylaxis reduces major cardiovascular morbidity and length of stay after cardiac surgery; a meta-analysis. Annals of Internal Medicine (2005): 143:327.

Bojar, RM (2005) Manual of Perioperative Care in Cardiac Surgery. 4th

Edition. Malden, MA: Blackwell Science. Belzberg, H., & Rivkind, A. “Preoperative cardiac preparation” Chest

(1999): 115:82S-95S. Centers for Disease Control (CDC) (1999) “Recommendations for

Prevention of Surgical Site Infection” Available at www.cdc.gov.

Crystal,E., Connolly, S.J. et al. Interventions for preventing postoperative atrial fibrillation in patients undergoing heart surgery. Cochrane Database Systematic Review 2004; 106:75.

DiDomenico, R.J. & Massad, M.G. “Pharmacological strategies for Prevention of Atrial Fibrillation After Open Heart Surgery” Ann Thoracic Surg 2005: 79:728 – 40.

Handbook of Patient Care in Cardiac Surgery, 7th Ed., Lippincott Williams & Wilkins. In Books@Ovid-LVWW Doody’s CoreTitle Collections 2010.

Eagle, L.A. & Guyton, R.A. “ACC/AHA 2004 guideline update for coronary artery bypass graft surgery; a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines” Circulation (2005): 111:2014.

Jolles, H., Henry, D.A. et al. (1996) “Mediastinitis following median sternotomy; CT findings. Radiology, 201:463-6.

Maluk, V. & Macpherson, D.S. (2010) “Perioperative medication management” in UpToDate, www.uptodate.com. Last date of modification 2/17/2010.

Mangram, A.J., Horan, T.C. et al. (1999) Guideline for Prevention of Surgical Site Infection. Infection Control and Hospital Epidemiology 20:4(250-278).

Silvestry, F., (2010) “Overview of the postoperative management of patients undergoing cardiac surgery” UpToDate, www.uptodate.com. Last date of modification 9/22/10

Wiegand, D,J, Carlson, K.K. (2010) Procedure Manual for Critical Care, 6th Edition. St. Louis, MO: Elsevier Saunders.

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