CORRELATION OF SALIVARY MUCIN MG2 AND THE PREVALENCE OF BABY

BOTTLE TOOTH DECAY

Mochamad Fahlevi RizalEndang W Bachtiar

Boy M BachtiarHeriandi Sutadi

Introduction

Caries Prevalence in Indonesia

Baby bottle tooth decay

Caries Detection for Children

Mucin MG2 responsible to Streptococcus mutans adhesion

Mucin MG2 and Streptococcus mutans

Salivary mucin MG2

α-enolase Streptococcus mutans

Salivary Protein

Mucin MG2 Single monomeric protein

Molecular weigth are less then mucin MG1

Sintesized in acinar serous cell and detected in all sero mucous salivary glands

Adhere with much oral bacteria such as Streptococcus mutans

Methods Consecutive Sampling Inclusion criteria: children between 3 – 5

yo who have dringking milk by bottle history

Unstimulate saliva collecting

ELISA method with anti mucin MG2 antibody in 450 nm

Result

Jumlah Kerusakan Gigi Jumlah Sampel

Rata-rataNilai OD

Mucin

Analisis Anova Sum of Squares F Sig.

Bebas Karies 17 0.194206 Between Groups

0.045 4.450 0.016

Karies 1- 5 Gigi 25 0.152280

Within Groups 0.297Karies > 5 gigi 20 0.213925

Total 62 0.183661 Total 0.342

Salivary Mucin MG2

deft

1614121086420-2

.5

.4

.3

.2

.1

0.0

-.1

Observed

Cubic

Discussion

Caries prevalence was represented by deft

Incresing mucin MG2 concentration will increase caries insidence

Discussion Mucin MG2 will used to:

- caries prediction

- caries prevention

Conclussion Mucin MG2 correlate to caries prevance

in baby bottle tooth decay and could be a caries predictor and a tool to prevent caries molecularly

Acknowledgement Part of this research was supported by

Risbin Iptekdok Grant Research 2007 from Department of Health Republic of Indonesia

Thank You