C H I C A G O 2 0 1 0

P R E L I M I N A R Y P R O G R A M

H I L T O N C H I C A G O

A P R I L 2 1 - 2 4 , 2 0 1 0

I N T E R N AT I O N A L S O C I E T Y F O R H E A R T A N D L U N G T R A N S P L A N TAT I O N3 0 T H A N N I V E R S A R Y M E E T I N G & S C I E N T I F I C S E S S I O N S

R e g i s t r a t i o n a n dH o u s i n g F o r m s

E n c l o s e d

2 0 0 9 - 2 0 1 0 B O A R D O F D I R E C T O R S

OfficersJames K. Kirklin, MD, PresidentJohn Dark, MB, FRCS, President-ElectMandeep R. Mehra, MD, Past-President; Editor, Journal of Heart and Lung TransplantationHeather J. Ross, MD, FRCPC, Secretary Treasurer

DirectorsSusan M. Chernenko, RN, MN, NPDuane Davis, MDRoger W. Evans, PhDAllan R. Glanville, MD, FRACPTakeshi Nakatani, MD, PhDJayan Parameshwar, FRCPStuart C. Sweet, MD, PhDJ. David Vega, MDFlorian M. Wagner, MDLori J. West, MD, D.PhilAndreas O. Zuckermann, MD

Ex-officio Board MembersMarshall I. Hertz, MD, Transplant Registry Medical DirectorHermann Reichenspurner, MD, PhD, Scientific Program Chair

Amanda W. RoweExecutive Director

Phyllis GlennDirector of Membership Services

Lisa A. EdwardsDirector of Meetings

Lee Ann MillsDirector of Operations

Susie NewtonAdministrative Assistant/Web Master

14673 Midway Road, Suite 200Addison, TX 75001Phone: 972-490-9495Fax: 972-490-9499www.ishlt.org

INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION

S T A F F

December, 2009

Dear Colleague:

On behalf of the International Society for Heart and Lung Transplantation and the Program Committee, it is my pleasure to invite you to attend the Society’s 30th Anniversary Meeting and Scientific Sessions to be held April21-24, 2010 at the Hilton Chicago in Chicago, Illinois. The preliminary program, registration and housing forms are enclosed (and are also available at www.ishlt.org). The objective of this year’s meeting is to provide you with leadingedge scientific updates and practical information that will be immediately applicable to your practice in the manage-ment of end stage heart and lung failure.

We have planned a comprehensive scientific program for you. On Wednesday, the meeting will begin at 7:00am with 5 sunrise symposia from 7:00 am – 8:00 am, followed by 12 satellite symposia from 8:15 am – 12:30 pm andthen a set of 5 mini oral sessions. After a brief break for lunch on your own, we will formally open the meeting with theOpening Plenary Session at 2:30 pm, followed by concurrent sessions. The meeting will continue on Thursday andFriday and will conclude on Saturday with 4 sunrise symposia, a Plenary Session, and the top-rated concurrent sessions.The meeting will conclude at Noon. Please note that immediately following this year’s meeting, ISHLT will conductthe first ISHLT Academy course. This course will be devoted to End Stage Heart Failure Core Competencies and will take place from 2:00 pm on Saturday until Noon on Sunday. See the section at the end of this program for moredetails and registration information. Attendance for the ISHLT Academy course is limited to 150 in order to maximizedelegate/faculty interaction.

We received 817 abstracts this year. To accommodate all of the excellent abstracts that were submitted, wehave organized 46 concurrent sessions, running six at a time. We have also expanded the mini oral sessions to a total of nine and have scheduled more than 200 general posters. It will be a very packed meeting, but the science will be excellent. We hope that you find this expanded format to be valuable, and we would appreciate your feedback.

I encourage you to register now – this promises to be a stimulating meeting with a blend of novel scientific research and comprehensive lectures on contemporary and controversial topics in the treatment of end-stage heart and lung disease and transplantation.

See you in Chicago!

Hermann Reichenspurner, MD, PhD2010 Scientific Program Chair

Chicago, also known as the Windy City, the

Second City, and the City of Big Shoulders,

is a city of world-class status and unsur-

passed beauty. Located on the shores of

Lake Michigan in the heart of the Midwest,

Chicago is home to world-championship

sports teams, an internationally acclaimed

symphony orchestra, renowned architec-

ture, award-winning theater and much

more. Today, Chicago has become a global

city, a thriving center of international

trade and commerce and a place where peo-

ple of every nationality come to pursue

their dreams.

The International Society for Heart and

Lung Transplantation (ISHLT) is a not-for-

profit, multidisciplinary, professional

organization dedicated to improving the

care of patients with advanced heart or

lung disease through transplantation,

mechanical support and innovative thera-

pies via research, education and advocacy.

ISHLT was created in 1981 at a small gath-

ering of about 15 cardiologists and cardiac

surgeons. Today we have over 2500 mem-

bers from over 45 countries, representing

over 10 different disciplines involved in

the management and treatment of end-stage

heart and lung disease. This multinational,

multidisciplinary mix is one of the biggest

strengths of the Society. It brings greater

breadth and depth to our educational of-

ferings and provides an exceptional envi-

ronment for networking and exchanging

information on an informal basis.

Our members include anesthesiologists,

basic scientists, cardiologists, cardiotho-

racic surgeons, ethicists, immunologists,

nurses, pathologists, perfusionists, phar-

macists, pulmonologists, tissue engineers,

and transplant coordinators. Despite their

differing specializations, all ISHLT mem-

bers share a common dedication to the

advancement of the science and treatment

of end-stage heart and lung disease.

A B O U T I S H L T

T H E P U R P O S E S O F T H E S O C I E T Y A R E

To associate persons interested in the fields of heart and lung transplan-tation, end-stage heart and lung disease, and related sciences.

To encourage and stimulate basic and clinical research in these disci-plines and to promote new therapeutic strategies.

To hold scientific meetings featuring presentations and discussions relevant to these disciplines.

To sponsor a scientific journal for the publication of manuscripts relatedto these disciplines.

To establish and maintain an international registry for heart and lungtransplantation.

To award research grants and establish endowments for the study ofthese disciplines.

A B O U T C H I C A G O

I N T E R E S T I N G W E B S I T E S

For more information about attractions in Chicago, please visit the following web sites:http://wikitravel.org/en/Chicago (quick overview)

http://www.choosechicago.com (convention and visitor’s bureau site)

http://www.lonelyplanet.com/usa/chicago (travel guide site)

http://www.frommers.com/destinations/chicago (travel guide site)

Temperatures during our meeting should be between 42-59 degrees F (6-15 degrees C). Rain is not unusual this time of year,

but the ISHLT meeting has always enjoyed fabulous weather wherever we meet, so we are hoping for the same in Chicago.

T E M P E R A T U R E A N D S P R I N G T I M E W E A T H E R

The President’s Gala Reception

will be held Friday, April 23

from 8:00 pm – 10:00 pm inside

the beautiful Grand Ballroom of

the Chicago Hilton, known to

many of us from the famous

movie “The Fugitive.”

The talented Marginal Donors,

starring our own Heather Ross,

MD, will be performing for the

crowd. Please be sure to join

us for this wonderful event on

Friday evening.

One ticket to the Gala Reception

is included with each paid

registration. Additional tickets

may be purchased for $75 each.

P R E S I D E N T ’ S G A L A R E C E P T I O N

PROGRAM CHAIR: Hermann Reichenspurner, MD, PhD, University Heart Center Hamburg, GermanyPRESIDENT: James K. Kirklin, MD, University of Alabama at Birmingham, ALAllen S. Anderson, MD, University of Chicago Medical Center, Chicago, ILSharon A. Beer, RN, MSc, Queen Elizabeth Hospital, Birmingham, United KingdomTuvia Ben Gal, MD, Rabin Medical Center, Petah Tikva, IsraelGerald J. Berry, MD, Stanford University, Stanford, CARoberta C. Bogaev, MD, FACC, Texas Heart Institute, Houston, TXJohn V. Conte, MD, Johns Hopkins Hospital, Baltimore, MDJohn Dark, MB, FRCS, Freeman Hospital, Newcastle Upon Tyne, United KingdomDuane Davis, MD, Duke University Medical Center, Durham, NCDaniel F. Dilling, MD, Loyola University Medical Center, Maywood, ILGiuseppe G. Faggian, MD, University of Verona Medical School, Verona, ItalyPaul W. M. Fedak, MD, PhD, FRCSC, Foothills Medical Center, Calgary, Alberta, CanadaAndrew J. Fisher, FRCP, PhD, Institute of Cellular Medicine, Newcastle Upon Tyne, United KingdomKimberly L. Gandy, MD, PhD, Children’s Hospital of Wisconsin, Milwaukee, WIAllan R. Glanville, MD, FRACP. St. Vincent’s Hospital, Darlinghurst, NSW, AustraliaJan F. Gummert, MD, PhD, Herz-und Diabeteszentrum NRW, Bad Oeynhausen, GermanyMargaret M. Hannan, MD, Mater Hospital, Dublin, IrelandDaphne T. Hsu, MD, Children’s Hospital at Montefiore, Bronx, NYMandeep R. Mehra, MD, JHLT Editor, University of Maryland School of Medicine, Baltimore, MDBruno M. Meiser, MD, Herzchirurgische Klinik und Poliklinik, Munchen, GermanyOmar A. Minai, MD, Cleveland Clinic Foundation, Cleveland, OHMartha L. Mooney, MD, Sentara Norfolk Transplant Center / EVMS, Norfolk, VAMichael G. Petty, PhD(c), RN, CCNS, CNS, University of Minnesota Medical Center, Minneapolis, MNRichard N. Pierson, III, MD, University of Maryland, Baltimore, MDHeather J. Ross, MD, MHSc, FRCP(c), Toronto General Hospital, Toronto, Ontario, CanadaSonja Schrepfer, MD, PhD, University Heart Center Hamburg, GermanyRandall C. Starling, MD, MPH, The Cleveland Clinic Foundation, Cleveland, OHMarc A. Stern, MD, Hopital Foch, Suresnes cedex, FranceDavid O. Taylor, MD, Cleveland Clinic Foundation, Cleveland, OHGeert M. Verleden, MD, PhD, University Hospital Gasthuisberg, Leuven, BelgiumFlorian M. Wagner, MD, University Hospital Eppendorf, Hamburg, GermanyMarian Zembala, MD, PhD, FESC, Silesian Medical School, Zabrze, Poland

Maria G. Crespo Leiro, MD,Unidad de Insuficiencia Cardiaca yTrasplante Cardiaco, La Coruna,SpainLara Danziger-Isakov, MD, MPH,The Cleveland Clinic Foundation,Cleveland, OHTobias Deuse, MD, PhD, UniversityHeart Center Hamburg, GermanyAnnette DeVito Dabbs, RN, PhD,University of Pittsburgh School ofNursing, Pittsburgh, PAFabienne Dobbels, MSc, PhD, University Hospital Leuven, BelgiumBrooks S. Edwards, MD, MayoClinic, Rochester, MNThomas M. Egan, MD, MSC, University of North Carolina Schoolof Medicine, Chapel Hill, NCHoward Eisen, MD, Drexel University College of Medicine,Philadelphia, PAAly El Banayosy, MD, Penn State Hershey Medical Center, Hershey, PAOkan Elidemir, MD, Texas Children’sHospital, Houston, TXStephan Ensminger, MD, PhD, University of Erlangen-Nurnberg, Erlangen, GermanyMichiel E. Erasmus, MD, PhD, University Medical Center Groningen,The NetherlandsRoberto Fiocchi, MD, PhD, Os-pedali Riuniti di Bergamo, ItalyMichael C. Fishbein, MD, UCLASchool of Medicine, Los Angeles, CAJuliet E. Foweraker, MD, PhD, Papworth Hospital NHS Founda-tion Trust, Cambridge, United KingdomRobert Frantz, MD, Mayo Clinic,Rochester, MNDarren H. Freed, MD, PhD,FRCSC, St. Boniface General Hospital, Winnipeg, Manitoba,Canada

Dan Admon, MD, Hadassah University Hospital, Jerusalem, IsraelAnnalisa Angelini, MD, Universita Di Padova, ItalySelim M. Arcasoy, MD, ColumbiaUniversity, New York, NYAbbas Ardehali, UCLA School ofMedicine, Los Angeles, CAJames B. Atkinson, MD, PhD, Vanderbilt University Medical Center, Nashville, TNCarla C. Baan, PhD, Erasmus MC,Rotterdam, The NetherlandsDavid A. Baran, MD, Newark Beth Israel Medical Center, Newark, NJJuergen Behr, MD, University of Munich, GermanyChristian Benden, MD, UniversityHospital Zurich, SwitzerlandAlexandria Berg, RN, Children’sHealthcare of Atlanta, GASangeeta M. Bhorade, MD, University of Chicago, ILEmma Birks, MRCP, Harefield Hospital, Harefield, Middlesex, United KingdomAnnette Boehler, MD, University Hospital Zurich, SwitzerlandMichael Burch, MD, Great OrmondStreet Hospital, London, United KingdomAllen P. Burke, MD, University of Maryland Medical Center, Baltimore, MDJason D. Christie, MD, Universityof Pennsylvania, Philadelphia, PAPaul Corris, MB FRCP, Freeman Hospital, Newcastle, United KingdomMaria Rosa Costanzo, MD, MidwestHeart Specialists, Naperville, ILAngelika Costard-Jaeckle, MD, University Heart Center Hamburg,GermanyWilliam G. Cotts, MD, Bluhm Cardiovascular Institute, Northwest-ern University, Chicago, IL

A N N U A L M E E T I N G S C I E N T I F I C P R O G R A M C O M M I T T E E

A B S T R A C T R E V I E W E R S

James P. Gagermeier, MD, LoyolaUniversity Medical Center, Chicago,ILEdward Garrity, Jr., MD, Universityof Chicago Medical Center,Chicago, ILJames F. George, PhD, University of Alabama at Birmingham, ALReda Girgis, MB BCh, Johns Hop-kins University, Baltimore, MDDaniel J. Goldstein, MD, Monte-fiore Medical Center, Bronx, NYGonzalo V. Gonzalez-Stawinski,MD, The Cleveland Clinic Foundation, Cleveland, OHKate Gould, FRCPath, Freeman Hospital, Newcastle Upon Tyne,United KingdomCynthia Gries, MD, MSc, Univer-sity of Washington, Seattle, WAFinn Gustafsson, MD, PhD, Rigshospitalet, Copenhagen, DenmarkElizabeth Hammond, MD, LDS Hospital, Salt Lake City, UTAri L. J. Harjula, MD, Helsinki University Central Hospital,Helsinki, FinlandRay E. Hershberger, MD, Universityof Miami Miller School of Medi-cine, Miami, FLPeter M. Hopkins, FRACP, ThePrince Charles Hospital, Brisbane,AustraliaEvelyn Horn, MD, Well Cornell Medical Center, New York, NYShahid Husain, MD, MS, TorontoGeneral Hospital, Ontario, CanadaMartin Iversen, MD, PhD, Rigshos-pitalet, Copenhagen, DenmarkPeter Jaksch, MD, General HospitalVienna, AustriaRobert Jaquiss, MD, Arkansas Children's Hospital, Little Rock, ARValluvan Jeevanandam, MD, University of Chicago Hospitals,Chicago, ILAnnemarie Kaan, MCN, RN, St. Paul’s Hospital, Vancouver, British Columbia, CanadaWalter G. Kao, MD, FACC, University of Wisconsin School of Medicine, Madison, WIAnne Keogh, MBBS, MD, St. Vincent’s Hospital, Sydney, Australia

Shaf Keshavjee, MD, FRCSC,Toronto General Hospital, Toronto,Ontario, CanadaJames K. Kirklin, MD, University of Alabama at Birmingham, ALWalter Klepetko, MD, University of Vienna, AustriaJon Kobashigawa, MD, Cedars SinaiHeart Institute, Los Angeles, CAChristiane Kugler, PhD, HannoverMedical School, Hannover, GermanySudhir S. Kushwaha, MD, Mayo Clinic, Rochester, MNHans B. Lehmkuhl, MD, DeutschesHerzzentrum Berlin, GermanyPascal Leprince, MD, PhD, Hospital Pitie-SalpetriereDeborah J. Levine, MD, University of Texas Health Science Center, San Antonio, TXBronwyn J. Levvey, RN, Grad Dip Clin Ep, Alfred Hospital, Melbourne, AustraliaKatherine Lietz, MD, PhD, Yale University School of Medicine, New Haven, CTJane MacIver, RN, MSc, TorontoGeneral Hospital, Toronto, Ontario,CanadaDonna M. Mancini, MD, New York Presbyterian Hospital, New York, NYCharles C. Marboe, MD, College ofPhysicians & Surgeons, New York, NYSandra Martin, RN, MSN, Univer-sity Hospital Leuven, BelgiumStanley I. Martin, MD, Ohio StateUniversity Medical Center, Colum-bus, OHFrauke Mattner, MD, Hannover Medical Center, Hannover, GermanyKenneth McCurry, MD, ClevelandClinic Foundation, Cleveland, OHKeith McNeil, FRACP, MetroNorth Health Service District, Herston, Queenland, AustraliaFederica Meloni, MD, PhD, University of Pavia, ItalyCarmelo Milano, MD, Duke University Medical Center,Durham, NCHenrik Milting, PhD, Erich &Hanna Klessmann Institute, BadOeynhausen, Germany

Paul J. Mohacsi, MD, University Hospital, Berne, SwitzerlandJean-Francois Mornex, MD, HopitalLouis Pradel, Lyon, FranceMichiel Morshuis, MD, Heart Center NRW, Bad Oeynhausen,GermanyJonathan B. Orens, MD, Johns Hopkins University, Baltimore, MDRobert F. Padera, MD, PhD,Brigham & Women’s Hospital,Boston, MAElfriede Pahl Schuette, MD, Chil-dren’s Memorial Hospital, Chicago,ILScott M. Palmer, MD, MHS, DukeUniversity, Durham, NCMyung H. Park, MD, University ofMaryland School of Medicine, Baltimore, MDSi M. Pham, MD, University ofMiami/Jackson Memorial Hospital,Miami, FLSean P. Pinney, MD, Mount SinaiMedical Center, New York, NYChristophe Pison, MSC, MD, CHU de Grenoble, FranceJeffrey L. Platt, MD, University ofMichigan, Ann Arbor, MIJ. Eduardo Rame, MD, Penn Heartand Vascular Center, Philadelphia, PAVivek Rao, MD, PhD, Toronto General Hospital, Toronto, Ontario,CanadaOlaf Reinhartz, MD, Stanford University, Stanford, CAMauro Rinaldi, MD, IRCCS Policlinico San Matteo, Torino, ItalyMarlene Rose, PhD, Harefield Hospital, Harefield, United KingdomStuart Russell, MD, Johns HopkinsHospital, Baltimore, MDRobert J. Schilz, MD, Case WesternReserve University, Cleveland, OHFernanda P. Silveira, MD, Universityof Pittsburgh Medical Center, Pittsburgh, PALianne G. Singer, MD, FRCPC,Toronto General Hospital, Ontario,CanadaGregory I. Snell, FRACP, MBB, Alfred Hospital, Melbourne, Australia

Stuart C. Sweet, MD, PhD, St.Louis Children’s Hospital, St. Louis,MOGabor B. Szabo, MD, PhD, University of Heidelberg, GermanyJose Tallaj, MD, University of Alabama at Birmingham, ALHenry D. Tazelaar, MD, MayoClinic, Scottsdale, AZ Jeffrey J. Teuteberg, MD, University of Pittsburgh/Presbyterian,Pittsburgh, PAHendrik Treede, MD, UniversityHeart Center Hamburg, GermanyVincent G. Valentine, MD, University of Texas Medical Branch,Galveston, TXDirk Van Raemdonck, MD, PhD,University Hospital Gasthuisberg,Leuven, BelgiumJohan Vanhaecke, MD, UniversityHospital Gasthuisberg, Leuven, BelgiumErik A. M. Verschuuren, MD, PhD,University Medical Centre, Groningen, The NetherlandsRobert G. Weintraub, MB BSFRAC, Royal Children’s Hospital,Parkville, Victoria, AustraliaRichard D. Weisel, MD, TorontoGeneral Hospital, Toronto, Ontario,CanadaLori J. West, MD, DPhil, Universityof Alberta, Edmonton, CanadaGlen P. Westall, FRACP, PhD, Melbourne, AustraliaConnie White-Williams, PhD, University of Alabama at Birmingham, ALGayle L. Winters, MD, Brigham &Women’s Hospital, Boston, MAThorsten Wittwer, MD, PhD, MA,University Hospital of Cologne, GermanyJoseph Woo, MD, University of Pennsylvania Health System, Philadelphia, PARoger Yusen, MD, MPH, Washington University School ofMedicine, St. Louis, MOMichael Zakliczynski, MD, Silesian Centre for Heart Disease,Gliwice, PolandAndreas O. Zuckermann, MD, University of Vienna, Austria

A B S T R A C T R E V I E W E R S C O N T I N U E D

MEETING LOCATIONUnless otherwise noted, all meet ings and activitieswill take place at the Hilton Chicago. The HiltonChicago hotel is a beautiful, landmark downtownChicago hotel located on the “Cultural MichiganAvenue Mile” overlooking Grant Park, Lake Michi-gan and Museum Campus.

MEETING REGISTRATIONRegistration for the meeting must be made via the ISHLT web site or via the Official ISHLT Registration Form. Online registration is stronglyencouraged. A $100 discount off the registrationfee is offered to those who register on or beforeMarch 10, 2010. Individuals who have not regis-tered by March 24, 2010 must register on-site atthe meeting. Confirmation letters will be emailedto all individuals who register by March 24, 2010.An Official ISHLT Registration Form is included inthis booklet and may be obtained from the SocietyHeadquarters (972-490-9495) and from our website (www.ishlt.org). ONLINE REGISTRATION ISSTRONGLY ENCOURAGED (www.ishlt.org). The reg-istration fee includes admittance into the SunriseSymposia, Satellite Symposia, Plenary Sessions,Concurrent Sessions, Mini Oral Sessions, GeneralPoster Sessions and Exhibit Hall. The registrationfee also includes coffee breaks each day, admittanceto the Opening Reception in the exhibit hall onWednesday evening, and one ticket to the Gala Reception on Friday evening.

G E N E R A L I N F O R M A T I O N

O N L I N E R E G I S T R A T I O N I S S T R O N G L Y E N C O U R A G E D

ISH

LTW

EDN

ESD

AYIN

TER

NAT

ION

AL

CO

NTI

NEN

TAL

BO

ULE

VAR

D

CO

NTI

NEN

TAL

CW

ALD

OR

F R

OO

MM

AR

QU

ETTE

P

DR

2SE

EX

HIB

IT H

ALL

AP

RIL

21

BA

LLR

OO

MA

/BR

OO

MR

OO

MSW

PO

STER

HA

LL7:

00 A

MSU

NRIS

E 1

SUNR

ISE

2SU

NRIS

E 3

SUNR

ISE

4SU

NRIS

E 5

VADS

Gon

e Ba

dRV

Fai

lure

Lung

Tx

Surg

ery

Pedi

atric

MCS

Nurs

ing

Case

s8:

00 A

M8:

15 A

MSA

TELL

ITE

1SA

TELL

ITE

2SA

TELL

ITE

3SA

TELL

ITE

4SA

TELL

ITE

5SA

TELL

ITE

6Ul

timat

e VA

DSPH

Inno

vatio

nsIn

crea

sing

Lun

g AM

R –

Part

1CA

VEm

ergi

ng ID

Dono

rs10

:15

AMCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKEX

HIBI

TS O

PEN

10:3

0 AM

SATE

LLIT

E 7

SATE

LLIT

E 8

SATE

LLIT

E 9

SATE

LLIT

E 10

SATE

LLIT

E 11

SATE

LLIT

E 12

GENE

RAL

POST

ERS

MCS

Eth

ics

PVD

Airw

ays

Infla

m.

AMR

–Pa

rt 2

HTX

Guid

elin

esNu

rsin

g10

am

–7:

30 p

m12

:30

PMM

ini O

ral S

essi

on 1

Min

i Ora

l Ses

sion

2M

ini O

ral S

essi

on 3

Min

i Ora

l Ses

sion

4M

ini O

ral S

essi

on 5

1:00

–2:

00 p

m1:

00 –

2:00

pm

1:00

–2:

00 p

m1:

00 –

2:00

pm

1:00

–2:

00 p

m2:

15 P

MOP

ENIN

GPL

ENAR

YSE

SSIO

N4:

45 P

MCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AK5:

15 P

MSE

SSIO

N 1

SESS

ION

2SE

SSIO

N 3

SESS

ION

4SE

SSIO

N 5

SESS

ION

6Pa

tient

s, P

umps

HTx

Dono

rs a

ndLT

x Pa

tient

Nurs

ing

Scie

nce:

Pedi

atric

Don

or a

ndPa

thol

ogy

and

Outc

omes

Outc

omes

Sele

ctio

nPa

tient

Exp

erie

nce

Patie

nt S

elec

tion

AMR

6:45

PM

EXHI

BIT

HALL

Open

ing

Rece

ptio

n6:

45 –

7:45

pm

ISH

LTTH

UR

SDAY

INTE

RN

ATIO

NA

LC

ON

TIN

ENTA

L B

OU

LEVA

RD

C

ON

TIN

ENTA

L C

WA

LDO

RF

RO

OM

MA

RQ

UET

TE

PD

R 2

SE E

XH

IBIT

HA

LLA

PR

IL 2

2B

ALL

RO

OM

A/B

RO

OM

RO

OM

SW P

OST

ER H

ALL

8:00

AM

8:30

AM

PLEN

ARY

SESS

ION

10:1

5 AM

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

EXHI

BITS

OPE

N10

:45

AMSE

SSIO

N 7

SESS

ION

8SE

SSIO

N 9

SESS

ION

10SE

SSIO

N 11

SESS

ION

12GE

NERA

L PO

STER

SM

CS P

atie

ntHT

x Do

nors

and

Lun

gPP

H Ri

skSt

em C

ells

: Bas

icIm

mun

osup

pres

sion

Sele

ctio

nOu

tcom

esOu

tcom

esFa

ctor

san

d Tr

ansl

atio

nal

Post

HTx

10 a

m –

4:45

pm

12:1

5 PM

JFTC

Men

tor L

unch

2:15

PM

2:30

PM

SESS

ION

13SE

SSIO

N 14

SESS

ION

15SE

SSIO

N 16

SESS

ION

17SE

SSIO

N 18

Devi

ce D

isas

ters

HTx

Post

-Op

Lung

Tx

Reje

ctio

nLu

ng D

onor

sPo

st-T

x QO

LTi

ssue

Gen

eDi

lem

mas

Regu

latio

n4:

00 P

MCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AK4:

30 P

MSE

SSIO

N 19

SESS

ION

20SE

SSIO

N 21

SESS

ION

22SE

SSIO

N 23

SESS

ION

24HT

x Im

mun

olog

yM

CS a

nd M

yocy

tes

Tran

spla

nt

Post

LTx

Pedi

atric

Tx

CHF

Outc

omes

Infe

ctio

nsIm

mun

osup

pres

sion

6:00

PM

Min

i Ora

l Ses

sion

6M

ini O

ral S

essi

on 7

Min

i Ora

l Ses

sion

8M

ini O

ral S

essi

on 9

7:00

PM

S C H E D U L E A T A G L A N C E

ISH

LTFR

IDAY

INTE

RN

ATIO

NA

LC

ON

TIN

ENTA

L B

OU

LEVA

RD

C

ON

TIN

ENTA

L C

WA

LDO

RF

RO

OM

MA

RQ

UET

TE

PD

R 2

SE E

XH

IBIT

HA

LLA

PR

IL 2

3B

ALL

RO

OM

A/B

RO

OM

RO

OM

SW P

OST

ER H

ALL

8:00

AM

8:15

AM

PLEN

ARY

SESS

ION

10:1

5 AM

BUSI

NESS

MEE

TING

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

EXHI

BITS

OPE

N10

:45

AMSE

SSIO

N 25

SESS

ION

26SE

SSIO

N 27

SESS

ION

28SE

SSIO

N 29

SESS

ION

30GE

NERA

L PO

STER

SM

CS C

osts

and

HTx

Risk

BOS

Risk

and

Dono

rIn

nova

tive

PHJu

nior

Fac

ulty

Outc

ome

Prev

entio

nM

anag

emen

tTh

erap

yCa

ses

10 a

m –

4:45

pm

12:1

5 PM

2:15

PM

2:30

PM

SESS

ION

31SE

SSIO

N 32

SESS

ION

33SE

SSIO

N 34

SESS

ION

35SE

SSIO

N 36

Whi

ch D

evic

eLu

ng R

epai

rHT

x He

art

Pedi

atric

Tx

Auto

imm

unity

Imm

unos

uppr

essi

onDo

nors

Reje

ctio

n4:

00 P

MCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AKCO

FFEE

BRE

AK4:

30 P

MSE

SSIO

N 37

SESS

ION

38SE

SSIO

N 39

SESS

ION

40SE

SSIO

N 41

EXHI

BIT

HALL

HTx

Chal

leng

esLT

x Fi

bros

is

Mol

ecul

arID

Def

initi

ons

RPT

CAVE

S Se

ssio

nPO

STER

HAL

LRe

ject

ion

STRI

KE8:

00 P

MGA

LA

GALA

GA

LA

GALA

GA

LA

GALA

GA

LA

4:30

pm

–M

idni

ght

ANNI

VERS

ARY

ANNI

VERS

ARY

AN

NIVE

RSAR

Y AN

NIVE

RSAR

YAN

NIVE

RSAR

YAN

NIVE

RSAR

YAN

NIVE

RSAR

YRE

CEPT

ION

RECE

PTIO

NRE

CEPT

ION

RECE

PTIO

NRE

CEPT

ION

RECE

PTIO

NRE

CEPT

ION

ISH

LTSA

TUR

DAY

INTE

RN

ATIO

NA

LC

ON

TIN

ENTA

L B

OU

LEVA

RD

C

ON

TIN

ENTA

L C

WA

LDO

RF

RO

OM

MA

RQ

UET

TE

PD

R 2

SE E

XH

IBIT

HA

LLA

PR

IL 2

4B

ALL

RO

OM

A/B

RO

OM

RO

OM

SW P

OST

ER H

ALL

7:00

AM

SUNR

ISE

6 SU

NRIS

E 7

SUNR

ISE

8SU

NRIS

E 9

EXHI

BIT

HALL

QOL

Lung

VADS

& In

fect

ions

LTx

Disa

ster

sSe

nsiti

zed

Patie

ntST

RIKE

8:00

AM

PLEN

ARY

SESS

ION

10:1

5 AM

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

COFF

EE B

REAK

10:3

0 AM

SESS

ION

42SE

SSIO

N 43

SESS

ION

44SE

SSIO

N 45

SESS

ION

46M

CS

LTx

HTx

Pedi

atric

Wha

t’s H

otCo

mpl

icat

ions

Com

plic

atio

nsCa

rdio

myo

path

ies

NOON

12:1

5 PM

COUN

CIL

RPTS

12:1

5 –

1:15

1:15

PM

2:00

PM

ISHL

T Ac

adem

y:Ad

vanc

ed H

eart

Failu

re a

nd C

ardi

acTr

ansp

lant

atio

nCo

re C

ompe

tenc

ies

M E E T I N G A B S T R A C T S / O N L I N E I T I N E R A R Y B U I L D E R

• ISHLT has arranged for a large block ofsleeping rooms at the Hilton Chicago located at 720 S. Michigan Avenue.

• To obtain a room within this block andat ISHLT rates, you must make yourreservation using the Official ISHLT Housing Form or online (see link on ISHLTHousing Form).

• A Housing Form is enclosed with thisprogram. Additional copies may be obtained from the Society web site(www.ishlt.org), the Society Headquartersat 972-490-9495, or you may photocopythe enclosed form.

• Hotel reservations must be made no laterthan March 26, 2010. Rooms are limited so please book early.

We will provide a copy of this supplement to the February issue of the Journal of Heart and Lung Transplantation to all scientific session registrants.

In addition, you can access our web site (www.ishlt.org) to review the detailed scientific program and abstracts and to createyour own personal itinerary for the meeting. You can also search the program for specific authors, keywords, and other fields. To use this service, please go to the ISHLT home page and follow the instructions.

H O T E L R E S E R VA T I O N S

C O N T I N U I N G M E D I C A L E D U C A T I O N I N F O R M A T I O N

ACCREDITATIONThis activity has been plannedand implemented in accordancewith the Essentials and Stan-dards of the Accreditation Council for Continuing MedicalEducation. The International Society for Heart and LungTransplantation is accredited bythe ACCME to provide continuingmedical education for physicians.ISHLT designates this activity for a maximum of 30.75 hours in Category 1 credit toward theAMA Physician’s RecognitionAward. Each physician shouldclaim only those hours of creditthat he/she actually spent inthe educational activity.

DISCLOSURECurrent guidelines state thatparticipants in CME activitiesmust be made aware of any affil-iation or financial interest thatmay affect the program contentor a speaker’s presentation.Planners, Faculty and Chairs participating in this meeting are required to disclose to theprogram audience any real orapparent conflict(s) of interestrelated to the content of theirpresentations or service asChair/Planner. These disclosureswill be printed in the Final Pro-gram and made available at themeeting. Additionally, all speak-ers have been asked to verballydisclose at the start of theirpresentation any financial interest or affiliations and to indicate if a product they arediscussing is not labeled for theuse under discussion or is stillinvestigational. ISHLT will en-sure that all conflicts of interesthave been resolved in accor-dance with ACCME requirementsfor the purpose of eliminatingbias in the presentation of edu-cational and scientific content.

TARGET AUDIENCEThe audience for this programincludes physicians, surgeons,scientists, nurses and transplantcoordinators engaged in thepractice of heart and lung trans-plantation, the managementand treatment of heart and lung transplant recipients, the management and treatment ofpatients with end-stage heart or lung disease, basic science or clinical research related tothese fields or specialties whichcause them to become involvedin the treatment of transplantrecipients or patients with end-stage heart or lung disease.

The educational goals and learn-ing objectives for this meetingwill be available on the ISHLTweb site (www.ishlt.org) in January, 2010.

S C I E N T I F I C P R O G R A M

Monday, April 19, 2010

12:00 PM – 8:00 PM

Island Exhibit Booth Installation (Southeast Exhibit Hall)

Tuesday, April 20, 2010

8:00 AM – 8:00 PM

Exhibit Booth Installation/Set-up (Southeast Exhibit Hall)

8:00 AM – 1:00 PM

ISHLT Board of Directors Meeting (Grand Tradition)

NOON – 8:00 PM

Poster Mounting (Southwest Exhibit Hall)

2:00 PM – 4:00 PM

Thoracic Registry Steering Committee Meeting (PDR 2)

Education Committee Meeting (PDR 4)

4:30 PM – 6:30 PM

Registries and Databases CommitteeMeeting (Joliet)

Standards and Guidelines Committee Meeting (PDR 4)

Communications Committee Meeting (PDR 2)

5:00 PM – 8:00 PM

Registration Desk Open (8th Street Registration)

5:00 PM – 8:00 PM

Slide Ready Room Open (Grand Tradition)

Wednesday, April 21, 2010

6:00 AM – 7:00 PM

Registration Desk Open (8th Street Registration)

6:00 AM – 7:00 PM

Slide Ready Room Open (Grand Tradition)

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 1:VADs Gone Bad Case Presentations(International Ballroom)

CHAIRS: O. HOWARD FRAZIER, MD ANDJOSEPH G. ROGERS, MD

Nicholas G. Smedira, MD, ClevelandClinic Foundation, Cleveland, OHRenzo Cecere, MD, Royal Victoria Hospital, Montreal, Quebec, CanadaStuart D. Russell, MD, Johns Hopkins Hospital, Baltimore, MDMartin Strueber, MD, Hannover MedicalSchool, Hannover, Germany

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 2:

Clinical Challenges in the Managementof Right Ventricular Failure(Continental A/B)CHAIRS: EVELYN HORN, MD AND

SRINIVAS MURALI, MD

This session will cover the clinical challenges associated with right ventricular failurefrom pathophysiology, diagnosis and treat-ment considerations in RV failure associatedwith secondary PH in patients with pul-monary and cardiac disorders. Specific focuswill be placed on management of RV dys-function in lung transplant and heart trans-plant candidates. 7:00 AM Assessment of RV Function:

Why is it Important and HowDo You Do It? Mardi Gomberg-Maitland, MD, MSc, Universityof Chicago, Chicago, IL

7:20 AM Optimal Timing for LungTransplant and the Implica-tions of LAS in Pulmonary Arterial Hypertension – Is ItEver Too Late? Adaani Frost,MD, Baylor University, Houston, TX

7:40 AM Pulmonary HypertensionTherapies and VAD Support:Do They Improve Candidacyfor Heart Transplant Candi-dates? Teresa De Marco, MD,FACC, University of California,San Francisco, CA

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 3:Surgical Approaches for Lung Trans-plantation – Is There Still a Debate?(Boulevard)CHAIRS: THOMAS K. WADDELL, MD, PHD

AND GILBERT MASSARD, MD

7:00 AM Clamshell With Tricks, DuaneDavis, MD, Duke University,Durham, NC

7:16 AM Sternal Sparing Clamshell,Bryan F. Meyers, MD, Wash-ington University School ofMedicine, St. Louis, MO

All meetings and activities

will take place at the Hilton

Chicago unless otherwise

specified. All papers will

be presented in English.

Speakers and Chairs have

been invited but not con-

firmed as of the date of the

printing of this program.

Meeting room assignments

are subject to change.

The Final Program, which

is distributed on site, will

reflect the latest session

schedule and room

assignments.

7:32 AM Sternotomy With Tricks, JohnDark, MB, FRCS, FreemanHospital, Newcastle, UnitedKingdom

7:42 AM Antero-Axillary Approach,Yoshiya Toyoda, MD, Univer-sity of Pittsburgh Medical Center, Pittsburgh, PA

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 4:Technical Issues in Mechanical Supportin the Pediatric Patient Case Presenta-tions (Continental C)CHAIRS: DAVID MORALES, MD AND

VICTOR O. MORELL, MD

Kimberly L. Gandy, MD, PhD, Children’sHospital of Wisconsin, Milwaukee, WIKirk R. Kanter, MD, Emory University, Atlanta, GABennett Pearce, MD, University of Alabamaat Birmingham, ALKristine Guleserian, MD, Children’sMedical Center, Dallas, TXAsif Hasan, MD, Freeman Hospital,Newcastle Upon Tyne, United Kingdom

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 5:Clinical Challenges for Nursing and Allied Health: What Would You Do?Case Presentations (Marquette)CHAIRS: ANNEMARIE KAAN, MCN, RN

AND MICHAEL G. PETTY,PHD(C), RN, CCNS, CNS

Health care practitioners consistently reportin our educational survey difficulty translat-ing clinical research outcomes into practice.In this session, through a case-study method-ology, participants will be offered the oppor-tunity to discuss with experienced healthcareprofessionals the application of such learningto specific care challenges.Daniela Roefe, RN, Heart Center NW,Bad Oeynhausen, GermanyCorby D’Amico, RN, MN, Emory University Hospital, Atlanta, GAChristine Hartley, MS, NP, Stanford University Medical Center, Palo Alto, CA

8:00 AM – 10:00 AM

Exhibit Booth Set-up (Southeast Exhibit Hall)

Poster Mounting (Southwest Exhibit Hall)

8:15 AM 10:15 AMSATELLITE SYMPOSIUM 1:The Ultimate VAD Symposium(International Ballroom)

CHAIRS: JAMES W. LONG, MD, PHD ANDGEORGE M. WIESELTHALER, MD

This session will provide the participantwith an overview of mechanical circulatorysupport from patient and device selection,RV function assessment and management,bridge to recovery – role of clenbuterol,bridge to candidacy in the morbidly obese,destination therapy in the elderly and management of the VAD recipient with hypertension. 8:15 AM Which Device for Which

Patient? Michiel Morshuis,MD, Heart Center NRW, BadOeynhausen, Germany

8:35 AM RV Failure: Prediction, Prevention and Treatment,Vivek Rao, MD, PhD, TorontoGeneral Hospital, Toronto, Ontario, Canada

8:55 AM Clenbuterol: Myth or Magic?Frances D. Pagani, MD, PhD,University of Michigan Hospi-tal, Ann Arbor, MI

9:10 AM VADs: Are They the UltimateWeight Loss Machines? RobertL. Kormos, MD, University ofPittsburgh Medical Center,Pittsburgh, PA

9:25 AM VAD: Are You Ever Too Old?,Thomas Krabatsch, MD, PhD,German Heart Institute, Berlin,Germany

9:40 AM Continuous Flow Devices:What Is Hypertension?Randall C. Starling, MD,MPH, Cleveland Clinic Foundation, Cleveland, OH

9:55 AM Panel Discussion

8:15 AM 10:15 AMSATELLITE SYMPOSIUM 2:Innovations in Pulmonary Hypertension:Advances in Medical and Surgical Therapies (Continental A/B)CHAIRS: MYUNG H. PARK, MD AND

OMAR MINAI, MD

This session will focus on the most currentup-to-date innovations in diagnosis, man-agement and research in pulmonary arterialhypertension (PAH). In 2009, the ACCF/AHA Executive Summary and reports fromthe 4th World Symposium were published.This session will feature highlights fromthose meetings and present updates on thecurrent guidelines in combination therapy,surgical therapy and upcoming new treat-ments in PAH. 8:15 AM New Mandates From The

ACCF/AHA Expert Consensusand 4th World Symposium On Pulmonary Hypertension,

Vallerie McLaughlin, MD, University of Michigan, AnnArbor, MI

8:30 AM Combination Therapy in Pul-monary Hypertension: Do WeHave the Evidence for it and Isit the Best Approach? Jean-LucVachiery, MD, Erasme Univer-sity Hospital-ULB, Brussels,Belgium

8:45 AM Risk Modeling in PulmonaryArterial Hypertension – Arethe Current Approaches Ade-quate? Robert P. Frantz, MD,Mayo Clinic, Rochester, MN

9:00 AM New Therapies on the Horizonin Pulmonary Arterial Hyper-tension – Going Beyond theThree Pathways, Paul A. Corris,MB FRCP, Freeman Hospital,Newcastle, United Kingdom

9:15 AM Beyond Medical Therapy –Surgical and Cellular Optionsfor Pulmonary Hypertension,Robert J. Schilz, MD, CaseWestern Reserve University,Cleveland, OH

8:15 AM 10:15 AMSATELLITE SYMPOSIUM 3:Getting to Yes – Increasing Lung Donors(Boulevard)CHAIRS: DIRK VAN RAEMDONCK, MD, PHD

AND BARTLEY P. GRIFFITH, MD

Donor lung utilization is still unacceptablylow and varies enormously between regions.Current donor utilization is only 15-20%of existing donors. This session will examinepossible approaches (clinical as well as inves-tigational) to improve organ availability.8:15 AM Introduction – What are the

Barriers? Where are the Opportunities? Duane Davis,MD, Duke University,Durham, NC

8:20 AM How To Optimize Donor LungProcurement, Charles W.Hoopes, MD, University ofCalifornia San Francisco, CA

8:40 AM Transplant Program DonorManagement – Increasing theDonor Pool, Gregory I. Snell,FRACP, MBB, Alfred Hospital,Melbourne, Australia

9:00 AM DCD Donors, Robert B. Love,MD, Loyola University MedicalCenter, Maywood, IL

9:20 AM State of the Art Ex Vivo Lung Perfusion, Shaf Keshavjee,MD, FRCSC, Toronto GeneralHospital, Toronto, Ontario,Canada

9:40 AM Resuscitation of the DonorLung, Florian M. Wagner, MD,University Heart Center Hamburg Eppendorf, Hamburg, Germany

8:15 AM 10:15 AMSATELLITE SYMPOSIUM 4:Management of the Sensitized Patientand Antibody Mediated Rejection: Part 1 (Continental C)CHAIRS: NANCY L. REINSMOEN, PHD

AND STEVEN D. ZANGWILL, MD

Several reports have demonstrated that pre-transplant sensitization to HLA antigensleads to a decrease in graft survival, an in-crease in rejection episodes, and the develop-ment of cardiac allograft vasculopathy(CAV) after heart transplantation andbronchiolitis obliterative syndrome (BOS)after lung transplantation. Further, the per-centage of sensitized thoracic organ candidatesreceiving transplants is far less than nonsen-sitized patients leading to increased time onthe waitlists and increased death on thewaitlists. This proposed session is designed toaddress the assessment and impact of HLAspecific antibodies in thoracic organ trans-plantation. New cutting edge technologiesallow for the identification of donor anti-gens to be avoided to increase the donor poolfor these sensitized patients. UNOS is im-plementing a calculated PRA to screendonors with unacceptable antigens and toindicate what percentage of the donor poolwould be expected to be incompatible for agiven patient. Other desensitization thera-pies are being used to decrease the strengthand breadth of the antibody load again toincrease the donor pool. Post-transplantmonitoring strategies are being utilized toidentify patients at risk for immune compli-cations and allow for therapeutic interven-tion. Several investigators are studying thepathology and clinical implication of donorHLA specific antibodies and efficacy oftreatment. This program will attempt to address these issues relevant to thoracic trans-plantation. 8:15 AM Biology of Antibody Mediated

Rejection, Elaine F. Reed, PhD,UCLA Immunogenetics Center,Los Angeles, CA

8:35 AM Techniques for Pre- and Post-Transplant Antibody Surveil-lance, Adriana Zeevi, PhD,University of Pittsburgh Med-ical Center, Pittsburgh, PA

9:05 AM The Crossmatch: How to Do itand How to Interpret it, JosefStehlik, MD, MPH, Universityof Utah, Salt Lake City, UT

9:25 AM Post-Op Monitoring and Di-agnosis of Antibody MediatedRejection, Margaret M. Burke,FRCPath, Harefield Hospital,Harefield, Middlesex, UnitedKingdom

9:45 AM Access for Sensitized Patients –A National Algorithm, Lori J.West, MD, DPhil, University ofAlberta, Edmonton, Canada

10:05 AM Panel Discussion

8:15 AM 10:15 AMSATELLITE SYMPOSIUM 5:Cardiac Allograft Vasculopathy: From Bench to Bedside (Waldorf )CHAIRS: JEFFREY L. PLATT, MD AND

HANNAH A. VALANTINE, MD

Despite the availability of new immunosup-pressive therapies, graft vasculopathy remainsa leading cause of graft loss following cardiactransplantation. This symposium is designedto bring together researchers from all per-spectives to develop new approaches to thetreatment of this problem. This session willeducate the basic scientist, translational researcher and clinician about the patho-physiology, clinical manifestations, treatmentand outcomes of graft vasculopathy in theheart transplant recipient.8:15 AM The Role of Innate Immunity

in the Development of Allo-graft Vasculopathy, TimothyD. Lee, PhD, Dalhousie Uni-versity Halifax, Nova Scotia

8:30 AM Adaptive Immunity in Allo-graft Vasculopathy, MarleneRose, PhD, Harefield Hospital,Harefield, United Kingdom

8:45 AM Prevalence, Detection andPrognosis of Graft Vasculopa-thy in Children, Elfriede PahlSchuette, MD, Children’s Me-morial Hospital, Chicago, IL

9:00 AM Non-Angiographic ImagingModalities for the Diagnosis of Graft Vasculopathy, JigneshPatel, MD, PhD, UCLA University CV Medical Group,Los Angeles, CA

9:15 AM How to Treat Graft Vasculopa-thy: Medical and CatheterBased Therapies, Howard J.Eisen, MD, Drexel UniversityCollege of Medicine, Philadel-phia, PA

9:30 AM Retransplantation: The Ulti-mate Treatment, Clifford Chin,MD, Stanford University, PaloAlto, CA

9:45 AM Panel Discussion

8:15 AM 10:15 AMSATELLITE SYMPOSIUM 6:Emerging Infectious Diseases: DonorManagement Issues and Recipient Sequelae (Marquette)CHAIRS: KATE GOULD, FRCPATH

AND STANLEY I. MARTIN, MD

The recent pandemic influenza and theSARS outbreak experience provide a natural“springboard” to discuss 1) the unfoldingof an emerging pathogen threatening car-diothoracic transplant activities concerningdonor, recipient, transplant teams and com-munity; 2) donor management issues toidentify the risks/testing- and its limitations;3) resources available, should donor trans-mitted infection be suspected: UNOS/CDC-donor derived infection advisoryboard, etc.; 4) how a donor- derived infec-tion presents post transplantation and howto diagnose and manage the recipient.8:15 AM Novel 2009 Influenza H1N1

Influenza Pandemic as aModel for an Emerging Infec-tion’s Impact on Cardiotho-racic Transplant Centers: TheAustralian Experience, Glen P.Westall, FRACP, PhD, Mel-bourne, Australia

8:35 AM Donor Derived Infections:Clinical Relevance and How to Avoid It – Evaluation andManagement at Time of Do-nation. The SARS Experience,Atul Humar, MD, University ofAlberta, Edmonton, Canada

8:55 AM Donor Derived Infections: Resources to Sort Out the Answers, Michael Ison, UNOS,DTAC, Northwestern Univer-sity, Chicago, IL

9:15 AM Donor Infections: DiagnosticTesting and Management to Minimize Risk, Paolo A. Grossi,MD, PhD, University of Insubria, Varese, Italy

9:40 AM Transmission of Tropical orGeographically Restricted Infections During Solid OrganTransplantation: ClinicalPresentation, Diagnostic Testing and Outcome, PatriciaMunoz, MD, Hospital GeneralUniversity Gregorio Marano,Madrid, Spain

10:00 AM Panel Discussion

9:00 AM – 5:00 PM

Press Office Open

10:00 AM – 7:30 PM

Exhibit Hall Open (Southeast Exhibit Hall)

Internet Café Open (Southeast Exhibit Hall)

Poster Viewing (Southwest Exhibit Hall)

10:15 AM – 10:30 AM

Coffee Break (Southeast Exhibit Hall)

Poster Viewing (Southwest Exhibit Hall)

10:30 AM 12:30 PMSATELLITE SYMPOSIUM 7:Who Plays God? Ethics in Transplanta-tion and Mechanical Circulatory Support Devices (International Ballroom)CHAIRS: HEATHER J. ROSS, MD, MHSC,

FRCP(C) AND HANS B.LEHMKUHL, MD

This session will provide an overview of themajor ethical issues that come into dailypractice.10:30 AM Re-Transplantation, Maryl R.

Johnson, MD, University of Wisconsin, Madison, WI

10:45 AM Multiorgan Transplant – Onefor You, Two or Three for Me,Mark Siegler, MD, Universityof Chicago, IL

11:00 AM End of Life/Palliative CareAfter Organ Transplantation,Savitri E. Fedson, MD, Univer-sity of Chicago Hospitals,Chicago, IL

11:15 AM When Do I Turn the VAD Off?Jane MacIver, RN, MSc,Toronto General Hospital,Toronto, Ontario, Canada

11:30 AM When to Say No – Does ItKeep You up at Night? MaryAmanda Dew, PhD, Universityof Pittsburgh School of Medi-cine, Pittsburgh, PA

11:45 AM Mechanical Circulatory Support Devices +/- Trans-plant in Congenital Heart Patients – Yes Or No? Beth D.Kaufman, MD, Children’s Hospital of Philadelphia, PA

NOON Panel Discussion

10:30 AM 12:30 PMSATELLITE SYMPOSIUM 8:Universal Issues in Tackling PulmonaryVascular Disease – Where Do We Stand?(Continental A/B)CHAIRS: RAYMOND L. BENZA, MD AND

DEBORAH J. LEVINE, MD

This session will cover key topics discussingdiagnosis and management of a secondaryPH commonly seen in clinical practice suchas PH associated with lung disease, chronic

thromboembolic disease and congenital heartdisease, as well as the current “hot” topic ofexercise and PH. 10:30 AM Report From the REVEAL

Registry – What Constitutesthe “Real” World PulmonaryHypertension Patient Popula-tion? Harrison W. Farber, MD,Boston University School ofMedicine, Boston, MA

10:50 AM Significance of Pulmonary Hypertension in ParenchymalLung Disease – Implicationsand Treatment, Reda Girgis,MB BCh, Johns Hopkins Uni-versity, Baltimore, MD

11:10 AM Chronic Thromboembolic Pul-monary Hypertension – WhenDoes Medical Therapy Have aPlace? Marion Delcroix, MD,University Hospital Leuven, Belgium

11:30 AM Congenital Heart Disease and Pulmonary Hypertension, CurtJ. Daniels, MD, Ohio State University, Columbus, OH

11:50 AM Exercise and Pulmonary Hypertension – How Far CanWe Push Our Patients? RonaldJ. Oudiz, MD, LA BiomedicalResearch Institute, Torrance, CA

10:30 AM 12:30 PMSATELLITE SYMPOSIUM 9:The Significance of Airways Inflamma-tion in Lung Allograft Dysfunction(Boulevard)CHAIRS: ANDREW J. FISHER, FRCP, PHD

AND SANGEETA M. BHORADE,MD

Airway inflammation is widely recognizedin patients developing lung allograft dys-function, however the role this plays in thepathogenesis of Bronchiolitis Obliterans Syn-drome and the best approach to its manage-ment remains unclear. Better understandingof lymphocytic bronchiolitis has been identi-fied by the ISHLT pulmonary council edu-cational survey as a key area for improvedunderstanding. This session will explore thepathology of airway inflammation in thetransplanted lung, examine any association between airway inflammation and acuteand chronic rejection and discuss the evi-dence to support approaches to management.10:30 AM The Pathology of Airways

Inflammation in the Trans-planted Lung, Susan Stewart,FRCPath, Papworth Hospital,Cambridge, United Kingdom

10:55 AM Is Airways Inflammation aForm of Acute Rejection?

Martin P. Iversen, MD, PhD,Rigshospitalet, Copenhagen,Denmark

11:15 AM Airways Inflammation as aRisk Factor for BronchiolitisObliterans Syndrome (BOS),Allan R. Glanville, MD,FRACP, Sydney, Australia

11:35 AM Treating Airways Inflamma-tion in the Lung Allograft,Geert M. Verleden, MD, PhD,University Hospital Gasthuis-berg, Leuven, Belgium

11:55 AM Panel Discussion

10:30 AM 12:30 PMSATELLITE SYMPOSIUM 10:Management of the Sensitized Patientand Antibody Mediated Rejection: Part 2 (Continental C)CHAIRS: J. DAVID VEGA, MD AND

UWE SCHULZ, MD

Several reports have demonstrated that pre-transplant sensitization to HLA antigensleads to decreased graft survival, an increasein rejection episodes, and the development ofcardiac allograft vasculopathy (CAV) afterheart transplantation and bronchiolitisobliterative syndrome (BOS) after lungtransplantation. Further, the percentage ofsensitized thoracic organ candidates receiv-ing transplants is far less than nonsensitizedpatients leading to increased time on thewaitlists and increased death on the wait-lists. This proposed session is designed to ad-dress the assessment and impact of HLAspecific antibodies in thoracic organ trans-plantation. New cutting edge technologiesallow for the identification of donor anti-gens to be avoided to increase the donor poolfor these sensitized patients. UNOS is im-plementing a calculated PRA to screendonors with unacceptable antigens and toindicate what percentage of the donor poolwould be expected to be incompatible for agiven patient. Other desensitization thera-pies are being used to decrease the strengthand breadth of the antibody load again toincrease the donor pool. Post-transplantmonitoring strategies are being utilized toidentify patients at risk for immune compli-cations and allow for therapeutic interven-tion. Several investigators are studying thepathology and clinical implication of donorHLA specific antibodies and efficacy oftreatment. This program will address theseissue relevant to thoracic transplantation.10:30 AM Management of the Sensitized

Adult Heart Candidate, StuartD. Russell, MD, Johns HopkinsHospital, Baltimore, MD

10:50 AM Management of the Sensitized Pediatric Heart Candidate,Steven A. Webber, MB ChB,Children’s Hospital, Pittsburgh,PA

11:10 AM Managing the Sensitized Lung Candidate, Kenneth R. Mc-Curry, MD, Cleveland ClinicFoundation, Cleveland, OH

11:30 AM Clinical Perspective of Anti-body Mediated Rejection,Abdalla G. Kfoury, MD,FACC, Intermountain MedicalCenter, Murray, UT

11:50 AM Results of the ISHLT Consen-sus Discussion Regarding AMRin Heart Tx: Implications forTreatment, Jon Kobashigawa,MD, Cedars Sinai Heart Insti-tute, Los Angeles, CA

12:10 PM Panel Discussion

10:30 AM 12:30 PMSATELLITE SYMPOSIUM 11:

The ISHLT Guidelines for Heart Transplant Recipients: Towards an International Consensus (Waldorf )CHAIRS: JAMES K. KIRKLIN, MD AND

MANDEEP R. MEHRA, MD

Currently there are no published consensuspractice guidelines addressing the care ofheart transplant recipients. ISHLT has justcompleted development of such a set of guide -lines. This session is intended to share withthe ISHLT membership the key consensusrecommendations for the care of heart trans-plant recipients, including early post-opera-tive care, Immunosuppression and long termcare.10:30 AM Introduction and Overview of

the Process, Maria RosaCostanzo, MD, Midwest HeartSpecialists, Naperville, IL

10:40 AM Perioperative Care of HeartTransplant Recipients: ReportFrom Task Force 1, Anne I.Dipchand, MD, Hospital forSick Children, Toronto, Ontario, Canada

11:00 AM Immunosuppression: ReportFrom Task Force 2, David O.Taylor, MD, Cleveland ClinicFoundation, Cleveland, OH

11:20 AM Long-Term Care of Transplant Recipients: Report From TaskForce 3, Sharon A. Hunt, MD,Stanford University MedicalCenter, Palo Alto, CA

11:40 AM Closing Remarks from Panel

11:45 AM Moderated Panel Discussion

10:30 AM 12:30 PMSATELLITE SYMPOSIUM 12:Transforming Transplant Care ThroughEvidence-Based Practice (Marquette)CHAIRS: LINDA OHLER, MSN, FAAN AND

JANE MACIVER, RN, MSC

There is little information addressing evi-dence-based nursing and allied health carein MCSD and transplant patients. A gapexists between the evidence that supportstransplant nursing and allied health careand daily care of the transplant patient. Thissymposium will present definitions, the gapsin the literature and current evidence-basednursing and allied health practice in trans-plantation. It will also foster audience dia-logue on these topics.10:30 AM Best Practice in Transplant

Care: A Road More or LessTraveled, Connie White-Williams, PhD, University ofAlabama at Birmingham, AL

10:40 AM Lung Transplantation: Evi-dence Based Nursing Practice:Are We There Yet? Susan M.Chernenko, RN, MN, NP,Toronto General Hospital,Toronto, Ontario, Canada

10:55 AM Care Management in the Pediatric Transplant Patient:Where is the Evidence? KarenC. Uzark, PhD, Children’s Hos-pital Heart Center, Cincinnati,OH

11:10 AM Evidence Based Practice ofSelf-Care Management in theAdult Mechanical CirculatorySupport and Transplant Patient: Is Your TransplantProgram Evidence Based?Kathleen L. Grady, PhD, APN,FAAN, Northwestern MemorialHospital, Chicago, IL

11:25 AM Mechanical Circulatory Support Infection ControlGuidelines: The Disconnect ofScience and Practice, Anne E.Dierlam, RN, Berlin HeartGmbH, Berlin, Germany

11:40 AM Transitioning the VAD Patient to Independence: Concept vs. Reality, Annemarie Kaan,MCN, RN, St. Paul’s Hospital,Vancouver, British Columbia,Canada

11:55 AM Professional Development and Contributions of the VAD Coordinator, Anthony W. Martin, APRN-BC, NewarkBeth Israel Medical Center,Newark, NJ

12:10 PM Panel Discussion

12:30 PM – 2:30 PM

Lunch Break

Poster Viewing

1:00 PM 2:00 PMMINI-ORAL SESSIONSSession 1 (Boulevard)CHAIRS: ROBERT L. KORMOS, MD AND

LESLIE W. MILLER, MD

Session 2 (Continental C)CHAIRS: UGOLINO LIVI, MD AND

AXEL HAVERICH, MD

Session 3 (Waldorf )CHAIRS: PETER JAKSCH, MD AND

ALFRED E. WOOD, FRCSI

Session 4 (Marquette)CHAIRS: RICHARD D. WEISEL, MD AND

ANDREAS O. ZUCKERMANN, MD

Session 5 (PDR 2)CHAIRS: JOSE A. TALLAJ, MD AND

DEBRA L. ISAAC, MD

2:30 PM 4:45 PMOPENING PLENARY SESSION(International Ballroom)CHAIRS: JAMES K. KIRKLIN, MD AND

HERMANN REICHENSPURNER, MD, PHD

2:30 PM President’s Welcome, James K.Kirklin, MD, University of Alabama at Birmingham, AL

2:35 PM Program Chair’s Report,Hermann Reichenspurner, MD,PhD, University Heart CenterHamburg, Germany

2:50 PM ISHLT International Thoracic Registry Report, Marshall I.Hertz, MD, University of Minnesota, Minneapolis, MN

3:20 PM INTERMACS Report, James K.Kirklin, MD, University of Alabama at Birmingham, AL

3:30 PM The Evolution of Lung Trans-plantation, Alec Patterson, Washington University School of Medicine, St. Louis, MO

3:50 PM Presidential Address, James K.Kirklin, MD, University of Alabama at Birmingham, AL

4:20 PM Margaret E. Billingham, MD Memorium/Pioneer Award Lecture, Dr. John Billinghamand Bruce A. Reitz, MD, Stanford University, CA

4:45 PM – 5:15 PM

Coffee Break (Southeast Exhibit Hall)

Poster Viewing (Southwest Exhibit Hall)

5:15 PM 6:45 PMCONCURRENT SESSIONS1: Patients, Pumps and Outcomes

(International Ballroom)CHAIRS: KATHERINE LIETZ, MD, PHD

AND ALY EL BANAYOSY, MD

2: Heart Transplant Outcome: Does theDonor Matter? (Continental A/B)

CHAIRS: ROBERTO FIOCCHI, MD, PHDAND KEITH D. AARONSON, MD

3: Observations on Candidate Selection for Lung Transplant (Boulevard)

CHAIRS: GEERT M. VERLEDEN, MD, PHDAND FEDERICA MELONI, MD,PHD

4: Nursing Science:…And Then WeWere Done: Patient Experience Following Surgical Interventions for Heart and Lung Failure(Continental C)

CHAIRS: SHARON A. BEER, RN, MSC ANDMICHAEL G. PETTY, PHD(C), RN,CCNS, CNS

5: Improving Donor and Recipient Selection in Pediatric Transplantation(Waldorf )

CHAIRS: LORI J. WEST, MD, DPHIL ANDROBERT G. WEINTRAUB, MB, BS,FRAC

6: The Antibody Mediated RejectionStory Continues (Marquette)

CHAIRS: MICHAEL C. FISHBEIN, MDAND MARGARET M. BURKE, FRCPATH

6:45 PM – 7:45 PM

Exhibit Hall Opening/Reception (Southeast Exhibit Hall)

View Posters (Southwest Exhibit Hall)

Thursday, April 22, 2010

7:00 AM – 7:00 PM

Registration Desk Open (8th Street Registration)

7:00 AM – 7:00 PM

Slide Ready Room Open (Grand Tradition)

8:30 AM 10:15 AMPLENARY SESSION(International Ballroom)CHAIRS: MANDEEP R. MEHRA, MD AND

JOHN WALLWORK, FRCS

8:30 AM Invited Lecture:The 2010 Post Heart Trans-plantation Guidelines, MariaRosa Costanzo, MD, MidwestHeart Specialists, Naperville, IL

8:45 AM Featured Abstract: (98)Comparison of Gene Expression Profiling and EndomyocardialBiopsy for Surveillance of AcuteCardiac Cellular Rejection: Results From the IMAGETrial, Michael X. Pham1,2, JeffJ. Teuteberg4, Abdallah G.Kfoury5, Randall C. Starling6,Mario C. Deng3, Thomas P.Cappola8, Andrew Kao9, AllenS. Anderson7, William G.Cotts10, Gregory A. Ewald13,David A. Baran12, Roberta C.Bogaev1, Helen Baron14, JamesYee14 and Hannah A. Valantine1.1Stanford University MedicalCenter, Stanford; 2VA Palo AltoHealth Care System, Palo Alto;3Columbia University MedicalCenter, New York; 4Universityof Pittsburgh Medical Center,Pittsburgh; 5IntermountainMedical Center and Intermoun-tain Healthcare, Salt Lake City,UT; 6Cleveland Clinic, Cleve-land, OH; 7University of ChicagoMedical Center, Chicago; 8Hos-pital of the University of Penn-sylvania, Philadelphia; 9MidAmerica Heart Institute, SaintLuke’s Hospital, Kansas City;10Northwestern Medical Center,Chicago; 11Texas Heart Insti-tute, Houston; 12Newark BethIsrael Medical Center, Newark,NY; 13Washington UniversitySchool of Medicine, St. Louis,MO and 14XDx Inc., Brisbane.

8:55 AM Invited Discussant:Nicholas R. Banner, FRCP,Harefield Hospital, Harefield,Middlesex, United Kingdom

9:00 AM Featured Abstract: (99) Risk ofBronchiolitis Obliterans Syn-drome is Twice as High in Cy-closporine Treated Patients inComparison to Tacrolimus 3Years After Lung Transplanta-tion: Results Of A ProspectiveRandomizedInternationalTrial Of 248 Patients, HendrikTreede1, Allan Glanville2, WalterKlepetko3, Raffael Lama4, Car-los Bravo5, Marc Estenne6, Jean-David Aubert7, ChristinaAboyoun2 and Hermann Re-ichenspurner1. 1Department ofCardiovascular Surgery, Univer-sity Heart Center Hamburg, Hamburg,Germany; 2Department of Pulmonology, St. Vincent’sHospital, Sydney, NSW, Aus-tralia; 3Department of Thoracic

Surgery, University Hospital Vienna, Vienna, Austria; 4Divi-sion of Thoracic Surgery, Uni-versity Hospital Reina Sofia,Cordoba, Spain; 5Departmentof Pneumology, Hospital Valld’Hebron, Barcelona, Spain;6Chest Service, Erasme Univer-sity Hospital, Brussels, Belgiumand 7Division of PulmonaryMedicine, University HospitalLausanne, Lausanne, Switzerland.

9:10 AM Invited Discussant:Paul A. Corris, MB FRCP, Freeman Hospital, Newcastle,United Kingdom

9:15 AM Invited Lecture:Prospect of Xenotransplanta-tion, Bruno Reichart, MD,University of Munich/Grossha -dern, Munich, Germany

9:35 AM Featured Abstract: (100) Impact of B-Cell Memory onDevelopment of Donor-Spe-cific Tolerance in ABO- Incom-patible Heart Transplantationin Early Childhood, SimonUrschel1, Lauren A. Ryan1, Myl-vaganam Jeyakanthan1, IngridM. Larsen1 and Lori J. West1.1Deaprtment of Pediatrics, Car-diac Transplant Research, Uni-versity of Alberta, Edmonton,AB, Canada.

9:45 AM Invited Discussant:Steven A. Webber, MB, ChB,Children’s Hospital of Pitts-burgh, Pittsburgh, PA

9:50 AM Featured Abstract: (101) AreRecipients From Heart DonorsListed as Homeless an In-creased Risk for Poor OutcomeAfter Heart Transplantation?Dorothy Lockhart1, Lynn Doer-ing1, Caron Burch1, Susan Mont-gomery1, Angela Velleca1,Jignesh Patel1, Michelle Kittle-son1, Stephanie Davis1, MattKawano1, Zach Goldstein1,Ariel Moradzadeh1, JaimeMoriguchi1, Abbas Ardehali1

and Jon Kobashigawa1. 1DavidGeffen School of Medicine atUCLA/Cedars Sinai Heart Institute, Los Angeles.

10:10 AM Invited Discussant:Duane Davis, MD, Duke University, Durham, NC

9:00 AM – 5:00 PM

Press Office Open

10:00 AM – 4:30 PM

Exhibit Hall Open (Southeast Exhibit Hall)

Internet Café Open (Southeast Exhibit Hall)

10:15 AM – 10:45 AM

Coffee Break (Southeast Exhibit Hall)

Poster Viewing (Southwest Exhibit Hall)

10:45 AM 12:15 PMCONCURRENT SESSIONS7: Battle of the Sexes: Patient Selection

(International Ballroom)CHAIRS: ROBERTA C. BOGAEV, MD, FACC

AND ANSON W. CHEUNG, MD

8: Heart Transplantation Outcomes(Continental A/B)

CHAIRS: GIUSEPPE FAGGIAN, MD ANDRANDALL C. STARLING, MD, MPH

9: Donor Influences on Outcomes AfterLung Transplant (Boulevard)

CHAIRS: STEPHEN C. CLARK, MD ANDDUANE DAVIS, MD

10: Novel Genomic, Proteomic and Clinical Risk Markers in PulmonaryArterial Hypertension(Continental C)

CHAIRS: JUERGEN BEHR, MD ANDKEITH MCNEIL, FRACP

11: Stem Cells: Basic and Translational Approaches (Waldorf )

CHAIRS: JOSEPH WOO, MD ANDTERRENCE M. YAU, MD, MSC

12: Immunosuppression After Heart Transplantation: Is Less More?(Marquette)

CHAIRS: BRUNO M. MEISER, MD ANDALLEN S. ANDERSON, MD, FACC

12:15 PM 2:15 PMJunior Faculty and Trainee Council Mentor Lunch (PDR 2)

2:30 PM 4:00 PMCONCURRENT SESSIONS13: Device Disasters: Can We Avoid

Them? (International Ballroom)CHAIRS: JAN F. GUMMERT, MD, PHD

AND FINN GUSTAFSSON, MD,PHD

14: Heart Transplantation Post-Op Dilemmas (Continental A/B)

CHAIRS: BROOKS S. EDWARDS, MDAND DONALD S. ESMORE, MBBS,FRACS

15: Clinical Investigation in Acute andChronic Rejection After Lung Trans-plantation (Boulevard)

CHAIRS: SCOTT M. PALMER, MD, MHSAND JONATHAN B. ORENS, MD

16: Every Breath I Take Is Now Better(Continental C)

CHAIRS: BRUCE A. REITZ, MD ANDTHORSTEN WITTWER, MD,PHD, M.A.

17: Quality of Life and Social Sciences:Have We Done the Right Thing?Assessing Quality of Life Following Cardiacthoracic Transplantation (Waldorf )

CHAIRS: BRONWYN J. LEVVEY, RN ANDCORBY L. D’AMICO, RN, MN

18: Tissue Gene Regulation and Protection from Injury (Marquette)

CHAIRS: STEPHAN M. ENSMINGER, MD,PHD AND CARLA C. BAAN, PHD

4:00 PM – 4:30 PM

Coffee Break (Southeast Exhibit Hall)

Poster Viewing (Southwest Exhibit Hall)

4:30 PM 6:00 PMCONCURRENT SESSIONS19: Clinical Heart Transplantation

and Immunology(International Ballroom)

CHAIRS: ADRIAN B. VAN BAKEL, MD,PHD AND MAURO RINALDI, MD

20: Getting Back to the Basics: Mechan-ical Circulatory Support Devicesand the Myocyte (Continental A/B)

CHAIRS: PAUL W. M. FEDAK, MD, PHD,FRCSC AND PASCAL LEPRINCE,MD, PHD

21: From Bench to Bedside Update inTransplant Infections (Boulevard)

CHAIRS: MARGARET M. HANNAN, MDAND MARTHA L. MOONEY, MD

22: Immunosuppression After Lung Transplantation: From Mouse toMan (Continental C)

CHAIRS: CYNTHIA J. GRIES, MD, MSCAND WALTER KLEPETKO, MD

23: Pediatric Transplantation InUnique Patient Populations(Waldorf )

CHAIRS: STUART C. SWEET, MD, PHDAND MICHAEL BURCH, MD

24: Heart Failure: Prognostication and Outcomes (Marquette)

CHAIRS: TUVIA BEN GAL, MD ANDDONNA M. MANCINI, MD

6:00 PM 7:00 PMMINI-ORAL SESSIONS

Session 6 (Boulevard)CHAIRS: ANGELIKA COSTARD-JAECKLE,

MD AND SEAN P. PINNEY, MD

Session 7 (Continental C)CHAIRS: MICHIEL E. ERASMUS, MD, PHD

AND HENDRIK TREEDE, MD

Session 8 (Waldorf )CHAIRS: ROBERT P. FRANTZ, MD AND

TOBIAS DEUSE, MD, PHD

Session 9 (Marquette)CHAIRS: CHRISTIAN BENDEN, MD AND

KRISTINE GULESERIAN, MD

6:00 PM 7:00 PMJunior Faculty and Trainee CouncilMeeting (PDR 2)

Friday, April 23, 2010

7:00 AM – 7:00 PM

Registration Desk Open (8th Street Registration)

7:00 AM – 7:00 PM

Slide Ready Room Open (Grand Tradition)

8:15 AM 10:15 AMPLENARY SESSION(International Ballroom)CHAIRS: JON KOBASHIGAWA, MD AND

MARK L. BARR, MD

8:15 AM Invited Lecture:Costimulation Blockade: Lessons of Kidney Transplan-tation, Implications For Thoracic Transplantation,Christian P. Larsen, MD,Emory University, Atlanta, GA

8:35 AM Featured Abstract: (257) Determinants of Survival inPatients Bridged to HeartTransplantation With Contin-uous-Flow Versus Pulsatile-Flow Ventricular AssistDevices, Jose N. Nativi1, AnnaY. Kucheryavaya2, Leah B. Ed-wards2, David Taylor3, MarshallI. Hertz4 and Josef Stehlik1.1UTAH Cardiac Transplant Program, University of Utah,Salt Lake City, UT; 2UnitedNetwork for Organ Sharing(UNOS), Richmond, VA; 3Car-diovascular Medicine, ClevelandClinic Foundation, Cleveland,OH and 4University of Min-nesota, Minneapolis, MN.

8:45 AM Invited Discussant:O. Howard Frazier, MD, TexasHeart Institute, Houston, TX

8:50 AM Featured Abstract: (258)Ex Vivo Lung Perfusion inClinical Lung Transplantation– The “HELP” Trial, MarceloCypel1, Jonathan C. Yeung1,Marc de Perrot1, Wojtek Karo-lak1, Fengshi Chen1, MasaakiSato1, Sassan Azad1, MindyMadonik1, Michael Hutcheon1,

Cecilia Chaparro1, Chung-WayChow1, Kazuhiro Yasufuku1, Andrew Pierre1, Lianne G.Singer1, Thomas K. Waddell1and Shaf Keshavjee1. 1TorontoLung Transplant Program, University of Toronto, Toronto,ON, Canada.

9:00 AM Invited Lecture: Organ Resuscitation of theHeart, Lung and Liver, ShafKeshavjee, MD, Toronto General Hospital, Toronto, Ontario, Canada

9:20 AM Featured Abstract: (259)Effect of Donor AssociatedCharacteristics on PrimaryGraft Dysfunction and Out-come After Cardiac Transplan-tation, Arezu Z. Aliabadi1,Stephane L. Mahr1, DanielaDunkler1, Farsad A. Eskandary1,Martina Groemmer1, DanielZimpfer1, Michael Grimm1, Guen-ther Laufer1 and Andreas O.Zuckermann1. 1CardiothoracicSurgery, Medical University ofVienna, Vienna, Austria; 2Wienand 3Wien.

9:30 AM Invited Discussant:Bruce Rosengard, MD,Philadelphia, PA

9:35 AM Featured Abstract: (260)Changes in the Causes ofHeart Transplant MortalityOver Two Decades: Successes,Failures, and Opportunities,David O. Taylor1, James K.Kirklin2, David C. Naftel2,Robert N. Brown2, Mark H.Drazner3, Tracy Stevens4, JohnM. Herre5, Josef Stehlik6 andDavid C. McGiffin2. 1ClevelandClinic, Cleveland, OH; 2Uni-versity of Alabama at Birming-ham, Birmingham, AL;3University of Texas Southwest-ern Medical Center, Dallas, TX;4Mid-America Heart Institute,Kansas City, MO; 5Sentara Car-diovascular Research Institute,Norfolk, VA and 6University ofUtah, Salt Lake City, UT.

9:45 AM Invited Discussant: Sharon A.Hunt, MD, Stanford University,Palo Alto, CA

9:50 AM Invited Lecture:RNAi and Heart Transplanta-tion, Weiping Min, MD PhD,University of Western Ontario,London, Ontario, Canada

9:00 AM – 5:00 PM

Press Office Open

10:00 AM – 4:30 PM

Exhibit Hall Open (Southeast Exhibit Hall)

Internet Café Open (Southeast Exhibit Hall)

10:15 AM – 10:45 AM

Coffee Break (Southeast Exhibit Hall)Poster Viewing (Southwest Exhibit Hall)

10:15 AM 10:45 AMANNUAL BUSINESS MEETING(International Ballroom)

10:45 AM 12:15 PMCONCURRENT SESSIONS25: Cost Effectiveness and Long-Term

Outcomes (International Ballroom)CHAIRS: CARMELO A. MILANO, MD AND

ROBERT F. PADERA, MD, PHD

26: Assessing the Risk of Heart Transplantation (Continental A/B)

CHAIRS: JOHN V. CONTE, MD ANDPAUL J. MOHACSI, MD

27: Bronchiolitis Obliterans Syndrome(BOS): Risk Factors and Prevention(Boulevard)

CHAIRS: ANNETTE BOEHLER, MD ANDALLAN R. GLANVILLE, MD,FRACP

28: Making a Better Breath(Continental C)

CHAIRS: ABBAS ARDEHALI, MD ANDFLORIAN M. WAGNER, MD

29: Pulmonary Hypertension: Innovation Therapy (Waldorf )

CHAIRS: REDA GIRGIS, MB, BCH ANDPATRICIA A. UBER, PHARMD

30: Clinical Case Dilemmas in Tho-racic Transplantation (Marquette)

CHAIRS: LORRIANA E. LEARD, MD ANDDANIEL F. DILLING, MD

10:45 AM Introduction, Lorriana E.Leard, MD, University of California, San Francisco, CA

10:50 AM Challenges in Lung TransplantationMODERATOR: Daniel F. Dilling,MD, Loyola University MedicalCenter, Maywood, ILPANELISTS: Robert B. Love,MD, Loyola University MedicalCenter, Maywood, IL and GeertM. Verleden, MD, PhD, Uni-versity Hospital Gasthuisberg,Leuven, Belgium

11:05 AM Challenges in Heart TransplantationMODERATOR: David W.Markham, MD, University of

Texas Southwestern MedicalCenter, Dallas, TXPANELISTS: Stuart D. Russell,MD, Johns Hopkins Hospital,Baltimore, MD and Leslie W.Miller, MD, Washington Hos-pital Center & GeorgetownUniversity Hospital, Washing-ton, DC

11:20 AM Infectious Disease Challengesin Thoracic TransplantationMODERATOR: Cynthia J. Gries,MD, MSc, University of Wash-ington, Seattle, WAPANELISTS: Aimee Zaas, MD,MHS, Duke University MedicalCenter, Durham, NC and KateGould, FRCPath, FreemanHospital, Newcastle UponTyne, United Kingdom

11:35 AM Challenges in Pulmonary HypertensionMODERATOR: Pali D. Shah,MD, Vanderbilt UniversityMedical Center, Nashville, TNPANELISTS: Teresa De Marco,MD, FACC, University of Cali-fornia, San Francisco, CA andRaymond L. Benza, MD, Allegheny General Hospital,Pittsburgh, PA

11:50 AM Challenges in Pediatric Tho-racic Transplantation

MODERATOR: Lorriana E. Leard,MD, University of California, San Francisco, CAPANELISTS: Cynthia S. Herring-ton, MD, Children’s HospitalLos Angeles, CA and Lori J.West, MD, D.Phil, Universityof Alberta, Edmonton, Alberta,Canada

2:30 PM 4:00 PMCONCURRENT SESSIONS31: The Menu: Which Device When?

(Continental A/B)CHAIRS: STEVEN S. L. TSUI, MD, FRCS

AND EMMA BIRKS, MRCP

32: Mechanisms of Inflammation and Repair in the Lung Allograft Airway(Boulevard)

CHAIRS: MARC ESTENNE, MD ANDGREGORY I. SNELL, FRACP, MBB

33: Heart Transplantation: Immunosuppression Controversies(Continental C)

CHAIRS: JOSEF STEHLIK, MD, MPH ANDARI L. J. HARJULA, MD

34: Healing My Broken Heart (Waldorf ) CHAIRS: GABOR B. SZABO, MD, PHD AND

VALLUVAN JEEVANANDAM, MD

35: New Approaches to the Evaluationand Treatment of Rejection in thePediatric Transplant (Marquette)

CHAIRS: OKAN ELIDEMIR, MD ANDOLAF REINHARTZ, MD

36: Autoimmunity, Tolerance and Inflammation (PDR 2)

CHAIRS: MARLENE ROSE, PHD ANDE. RENE RODRIGUEZ, MD

4:00 PM – 4:30 PM

Coffee Break (Southeast Exhibit Hall)

Poster Viewing (Southwest Exhibit Hall)

4:30 PM 6:00 PMCONCURRENT SESSIONS37: Heart Transplantation Clinical

Challenges (Continental A/B)CHAIRS: RAY E. HERSHBERGER, MD AND

GONZALO V. GONZALEZ-STAW-INSKI, MD

38: Lung Transplantation for Intersti-tial Lung Disease (Boulevard)

CHAIRS: VINCENT G. VALENTINE, MDAND CHRISTOPHE PISON, MD

39: Molecular Mechanisms of Organ Rejection (Continental C)

CHAIRS: JAMES F. GEORGE, MD ANDSONJA SCHREPFER, MD

40: Expert Consensus Definitions in Cardiothoracic Transplantationand Mechanical Circulatory Support Infections (Waldorf )

CHAIRS: STEPHAN SCHUELER, MD, PHDAND JOSE G. MONTOYA, MD

This session will present a summary of the completed consensus document on infectionsin cardiac transplantation and mechanicalcirculatory support, which will form thebasis for a set of international standardizedvariables for entry of infection data into theISHLT Registry and for future research.4:30 PM Definitions of Infection in Me-

chanical Circulatory Support,Margaret M. Hannan, MD,Mater Hospital, Dublin, Ireland

5:00 PM Definitions of Infection inHeart and Lung Transplanta-tion, Martha L. Mooney, MD,Sentara Norfolk TransplantCenter/EVMS, Norfolk, VA

5:30 PM Panel Discussion with Task-force Members

41: Philip K. Caves Award Candidate Presentations (Marquette)

CHAIRS: STUART D. RUSSELL, MD ANDLUCIANO POTENA, MD

4:30 PM – 11:59 PM

Exhibit Hall/Poster Tear Down

8:00 PM 10:00 PMGala Anniversary Reception(Grand Ballroom)

Saturday, April 24, 2010

6:30 AM – 10:30 AM

Registration Desk Open (8th Street Registration)

7:00 AM – 7:00 PM

Slide Ready Room Open (Grand Tradition)

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 6:Linking Outcomes and Quality of LifeAfter Lung Transplant (Boulevard)CHAIRS: SELIM M. ARCASOY, MD AND

MARTIN P. IVERSEN, MD, MPH

There has been a major focus on survivaland physical outcomes after lung transplant.This has, however, under-estimated the im-portance of quality of life assessment of out-comes. It is important that the wider lungtransplant community recognize the value ofquality of life assessment and its impact onoutcomes after lung transplant. This sessionwill investigate the associations between pa-tient quality of life and outcomes after lungtransplant.7:00 AM Interventions to Improve Ad-

herence After Thoracic OrganTransplantation, FabienneDobbels, MSc, PhD, UniversityHospital Leuven, Belgium

7:15 AM Integrated Survival and Quality of Life Outcomes inLung Transplantation, RogerD. Yusen, MD, MPH, Wash-ington University School ofMedicine, St. Louis, MO

7:30 AM Patient-Reported Outcomes in Lung Transplantation,Lianne G. Singer, MD, FRCPC,Toronto General Hospital, Ontario, Canada

7:45 AM Integrating Palliative Care inLung Transplantation, AnnetteJ. DeVito Dabbs, RN, PhD,University of Pittsburgh Schoolof Nursing, Pittsburgh, PA

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 7:Crossing the Lines (Continental C)CHAIRS: REYNOLDS M. DELGADO, MD

AND MARGARET M. HANNAN, MD

7:00 AM Central Lines Infections InCardiothoracic Transplanta-tion, Jose G. Montoya, MD,Stanford University School ofMedicine, Stanford, California

7:20 AM VAD Infections – Going Intothe Future and Learning Fromthe Past, Aly El Banayosy, MD,Penn State Hershey MedicalCenter, Hershey, PA

7:40 AM Definitions of VAD Infections,Drive-Line Infections, Pocket Infections, and Device Infec-tions, and their Applicationinto Databases for Future Research, William L. Holman,MD, University of Alabama atBirmingham, Alabama

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 8:Disasters Early After Lung Transplant(Waldorf )CHAIRS: THOMAS M. EGAN, MD, MSC

AND JOHN DARK, MB, FRCS

Unexpected events and early disasters con-tinue to challenge all centres, with a range ofpossible responses. A range of acute surgicaland medical problems and specific solutionsto these problems will be discussed.7:00 AM Unexpected PGD 1 Hypera-

cute Rejection, Duane Davis,MD, Duke University MedicalCenter, Durham, NC

7:10 AM Unexpected PGD 2 Left Heart Failure, David C. McGiffin,MD, University of Alabama atBirmingham, AL

7:20 AM Kinked PA/PV, Joshua Sonett,MD, Columbia PresbyterianMedical Center, New York, NY

7:30 AM Unexpected Donor Anatomy,Martin Strueber, MD, Han-nover Medical School, Han-nover, Germany

7:40 AM Technical Aspects of ECMO,Walter Klepetko, MD, Univer-sity of Vienna, Austria

7:00 AM 8:00 AMSUNRISE SYMPOSIUM 9:

Tough Cases in the Management of theSensitized Patient Case Presentations(Marquette) CHAIRS: ELIZABETH BLUME, MD AND

ELAINE F. REED, PHD

This symposium will address a practice gapin the diagnosis and management of the pa-tient who has evidence of anti-HLA anti-bodies undergoing transplantation. There is

a significant amount of controversy in sur-rounding the appropriate management ofthe highly sensitized patient and this sympo-sium will allow participants to understandthe state-of-the-art thinking in the field.This symposium will use a practical case-based approach to highlight the issues raisedin the transplantation of the highly sensi-tized patient undergoing heart or lung trans-plantation.Case Presentations:

PRESENTERS: Susan D. Moffatt-Bruce, MD, PhD, Ohio StateUniversity Medical Center,Columbus, OHJeffrey G. Gossett, MD, Chil-dren’s Memorial Hospital,Chicago, IL

DISCUSSANTS: Linda J. Ad-donizio, MD, Columbia Presby-terian Medical Center, NewYork, NYStephan M. Ensminger, MD,PhD, University of Eriangen-Nurnberg, Erlangen, Germany

8:00 AM 10:15 AMPLENARY SESSION(Continental A/B)CHAIRS: JOHN DARK, MB, FRCS AND

RICHARD N. PIERSON, III, MD

8:00 AM Invited Lecture:New Therapies for SensitizedRenal Allograft Recipients,Patrick G. Dean, MD, MayoClinic Transplant Center,Rochester, MN

8:20 AM Featured Abstract: (351)Are DCD Lungs Superior? Excellent Intermediate ResultsFrom a Donation After Car-diac Death Lung TransplantNational Collaborative,Bronwyn Levvey1, MichelleHarkess2, Daniel Chambers3,Emily Granger2, IshtiaqAhmed2, Peter Hopkins3, AllanGlanville2 and Greg Snell1.1Lung Transplant Service, TheAlfred Hospital, Melbourne,Vic, Australia; 2Lung Transplan-tation Unit, St Vincent’s Hospi-tal, Sydney, NSW, Australia and3QLD Center for PulmonaryTransplantation and VascularDisease, Prince Charles Hospi-tal, Brisbane, QLD, Australia.

8:30 AM Invited Discussant:Andres Varela, MD, Hospital Universita Puerta de Hierro

8:35 AM Featured Abstract: (352)Cardiac Resuscitation Follow-ing Circulatory Arrest in theOrgan Donor is AssociatedWith Excellent Functional and Metabolic Recovery: Implications for ClinicalHeart Transplantation, AyyazA. Ali1, Bo Xiang2, PaulWhite1, Steven Tsui1, EuanAshley3, Stephen R. Large1,Trevor W. Lee2, Rakesh Arora2,Ganghong Tian2 and DarrenH. Freed2. 1Cardiothoracic Sur-gery, Papworth Hospital, Cam-bridge, Cambridgeshire,United Kingdom; 2Surgery,University of Manitoba, Win-nipeg, MB, Canada and 3Car-diovascular Medicine, StanfordUniversity Medical Center,Palo Alto, CA.

8:45 AM Invited Discussant:Carmelo A. Milano, MD,Duke University Medical Center, Durham, NC

8:50 AM Invited Lecture:Stem Cell Tissue Engineering,Prof. Dr. Thomas Eschen-hagen, University HospitalHamburg-Eppendorf, Hamburg, Germany

9:10 AM Featured Abstract: (353)United States Lung AllocationScore Predicts HospitalCharges Post-Transplant,George J. Arnaoutakis1, Jere-miah G. Allen1, Christian A.Merlo2, William A. Baumgart-ner1, John V. Conte1 and AshishS. Shah1. 1Division of CardiacSurgery, Department of Surgery, The Johns HopkinsHospital, Baltimore, MD and2Division of Pulmonary andCritical Care Medicine, Department of Medicine, The Johns Hopkins Hospital,Baltimore, MD.

9:20 AM Invited Discussant:Edward R. Garrity, Jr., MD, University of Chicago MedicalCenter, Chicago, IL

9:25 AM Featured Abstract: (354)Serum IgA Deficiency is Com-mon in Lung Transplantationand is Independently Associ-ated With BronchiolitisObliterans Syndrome (BOS),Daniel C. Chambers1, BelindaDavies1, Stephanie Yerkovich1

and Peter M. Hopkins1.

1Queensland Centre for Pul-monary Transplantation andVascular Disease, The PrinceCharles Hospital, Brisbane,QLD, Australia.

9:35 AM Invited Discussant:Andrew J. Fisher, MD, Insti-tute of Cellular Medicine,Newcastle Upon Tyne, UnitedKingdom

9:40 AM Awards Presentation:Duane Davis, MD and JohnDark, MB, FRCS

9:55 AM Debate:Mechanical Circulatory Support is IN, Heart Transplantation is OUTPRO: O. Howard, Frazier, MD,Texas Heart Institute, Houston,TXCON: Mandeep R. Mehra, MD,University of Maryland Schoolof Medicine, Baltimore, MD

10:15 AM – 10:30 AM

Coffee Break

10:30 AM NOONCONCURRENT SESSIONS42: Blood, Clots and Antibodies

(Continental A/B)CHAIRS: DARREN H. FREED, MD, PHD,

FRCSC AND ROLAND HETZER,MD, PHD

43: Lung Transplantation Complications (Boulevard)

CHAIRS: MARC STERN, MD AND PETERM. HOPKINS, FRACP

44: Late Complications Post Heart Transplantation (Continental C)

CHAIRS: MARIAN ZEMBALA, MD, PHD,FESC ANDDANIEL J. GOLDSTEIN, MD

45: Transplantation for Pediatric Cardiomyopathies (Waldorf )

CHAIRS: KIMBERLY L. GANDY, MD, PHDAND CHARLES E. CANTER, MD

This symposium will provide important in-formation about the specific outcomes ofheart transplantation in children with dif-ferent classes of cardiomyopathies. This in-formation will be used to provide clinicianswith a better understanding of the risksand benefits of transplantation in childrenwith pediatric cardiomyopathies. This sym-posium will review the indications and out-comes of transplantation in patients withall forms of cardiomyopathy.

10:30 AM Classification of Cardiomy-opathies and Impact of Ge-netic Diagnosis on Prognosis,Jeffrey A. Towbin, MD,Cincinnati Children’s HospitalMedical Center, Cincinnati, OH

10:45 AM Indications and Outcomes ofListing for Transplantation inPediatric Cardiomyopathies,Daphne Hsu, MD, Children’sHospital at Montefiore, Bronx,NY

11:00 AM Which Patients, What Deviceand When to Use Mechanical Assist Support in PediatricCardiomyopathies? Robert D.B. Jaquiss, MD, Arkansas Chil-dren’s Hospital, Little Rock, AR

11:15 AM Outcomes of Transplantationin Patients With Dilated Cardiomyopathy, RichardKirk, MA FRCP FRCPCH,Freeman Hospital, NewcastleUpon Tyne, United Kingdom

11:30 AM Outcomes of Transplantationin Patients With RestrictiveCardiomyopathy, Steven D.Zangwill, MD, Children’s Hospital of Wisconsin, Milwaukee, WI

11:45 AMOutcomes of Transplantationin Patients With HypertrophicCardio myopathy, Robert J.Gajarski, MD, CS Mott Chil-dren’s Hospital, Ann Arbor, Ml

46: What’s Hot! Best Abstracts fromMechanical Circulatory Support,Heart Transplantation, LungTransplantation (Marquette)

CHAIRS: RICHARD N. PIERSON, III, MDAND HERMANN REICHEN-SPURNER, MD

12:15 PM 1:15 PMCouncil Reports to the Membershipand Board (Continental C)

1:30 PM 4:30 PMISHLT BOARD OF DIRECTORSMEETING (PDR 4)

In response to goals developed at the

2006-2007 Strategic Planning Meeting,

the ISHLT Education Committee is pleased

to announce the establishment of the

ishlt academy.

The ishlt academy draws on the wealth of experi-

ence and expertise within the society to deliver high

quality educational experiences with the goal of

enabling our members to improve and maintain

the highest possible standards in the care of patients

with advanced heart and lung disease and those

undergoing heart or lung transplantation.

The ishlt academy will operate under the auspices of

the ISHLT Education Committee. The ishlt academy

represents the ‘brand name’ that will be associated

with the educational opportunities offered by the

international society of heart and lung transplan-

tation to its members and interested non-members.

A N N O U N C I N G T H E

The purpose of the ishlt academy is to develop an enduringresource of education in core competencies in the field ofcardiopulmonary transplantation, mechanical and biologicalsupport of the failing heart, advanced lung disease (includingpulmonary vascular disease) and cell replacement therapy.These educational endeavors will complement the ISHLT’sexisting activities in the promulgation of new science, registryanalysis, guideline statements and monograph series as aconsolidated activity designed to train and educate youngclinicians, trainees and those looking for a refresher course inclinical practice mandates in the field.

The opportunities provided by the ishlt academy will bemulti-modality and multi-disciplinary and will be guided bythe identified educational needs or ‘practice gaps’ of ISHLTmembers. When available, core curriculum and competencydocuments for different disciplines within the society willguide content of academy activities. The activities of theacademy will run throughout the societies interface with itsmembers with material provided in written format via articlesin the Journal of Heart and Lung Transplantation, via theISHLT Monograph series and via educational meetings. Select educational activities included within the Annual Meetingwill also carry the academy brand and will run in concert withthe scientific content of the annual meeting.

The ishlt academy theme at this year’s annual meeting is “Heart Failure and Heart Transplantation.” You will find anumber of sessions in the program carrying the academylogo to highlight educational content that fits with thisyear’s ishlt academy theme. In addition, at the conclusionof the Annual Meeting, we will be conducting the firstishlt academy Masters Course on Advanced Heart Failure,Cardiac Transplantation and Mechanical Support.

You may register for this course via the Annual Meetingregistration form. Attendance at the Annual Meeting is NOT required in order to register for the Masters Academy Course.

Saturday, April 24, 2:00 pm– Sunday, April 25, NoonCHAIRS: James K. Kirklin, MD and

Mandeep R. Mehra, MD

This educational activity will offer 10hours of intensive teaching activity focusing on core competencies of Advanced Heart Failure, MechanicalCirculatory Support, Pulmonary Hypertension and Cardiac Transplan-tation. Registration for the program is limited to the first 150 registrants.

Registration for this Masters Academycourse is limited to the first 150 individuals. You may register via theRegistration Form included in thisbooklet. Registration for the ISHLT Annual Meeting is NOT required inorder to register for this course.

Saturday, April 24, 20101:50 pmScientific ProgramOpening Remarks

2:00 pmSESSION 1:Advanced Heart Failure AndHigh Risk SurgeryThis session will cover the followingtopics via lectures and panel discussion

Advanced Heart Failure:Overview

1) Diagnosis2) Etiology3) Approach to management4) Recent clinical trials and trials

in progress

Heart Failure: Prognosis1) Individual prognostic markers

and algorithms (SHFS, HFSS,EFFECT)

2) Overview of CPET

Advanced Heart Failure: Treatment

1) Current standard of care fortreatment of advanced HF

2) Timing of referral for advancedtherapies (MCSD, Transplant,CRT)

Indications for CRT1) Evidence-based approach to

patient selection and out-comes with CRT

2) Overview of off label indica-tions including the difficultcases (RBBB, AFib)

End-of-Life Care 1) Framework for assessing issues

in patients with advanced HFnearing end of life

2) Advanced care directives

4:15 pm BREAK

4:30 pmSESSION 2:Mechanical Circulatory SupportThis session will cover the followingtopics via lectures and panel discussion

Indications for MCS1) Short-term versus long-term

support2) Bridge to transplant, bridge to

recovery, and destination therapy

3) Left ventricular, right ventricu-lar, and bi-ventricular support

4) Bridge to transplant and desti-nation therapy CMS criteria

The Influence of Patient Selection on Outcomes

1) Identification of co-morbidities2) INTERMACS Classifications3) Review of Lietz-Miller Risk

Analysis of destination therapypatients

4) SHFM5) Importance of prognostic

models6) Correlation of risk factors and

outcomes

Classification of Pumps1) Centrifugal, pulsatile and axial2) Percutaneous, implantable

and paracorporeal3) Review of current FDA

approved VADs

Surgical Nuances –Intra-operative and Early Post-operative Management

1) Operative Techniques2) Use of TEE intra-operatively3) RV Function4) Suction Events5) Ventricular Arrhythmias6) Pulmonary Hypertension

The Nuts and Bolts of Outpatient Management 1) Blood pressure assessment

and management 2) Anticoagulation regimens3) Diagnosis and Management

of GI bleeding4) Thromboembolic Events

5) Driveline Infections6) Non-device related Infections

6:30 pm BREAK

7:00 pmSESSION 3: Dinner Session: Pictures AreWorth A Thousand Words: Imaging, Biopsies and HemodynamicsThis session will cover the followingtopics via case discussions and use ofan audience response system:

Advanced Heart Failure Cardiac Allograft VasculopathyAntibody-Mediated RejectionMechanical Circulatory SupportPulmonary Hypertension

Sunday, April 25, 20107:00 amContinental Breakfast

7:30 amSESSION 4: Cardiac TransplantationThis session will cover the following topics via lectures and panel discussion

1) Heart Transplant Candidacy 2) Immediate Post-Transplant

Care3) Immunosuppression4) Cellular and Antibody-Medi-

ated Rejection5) Cardiac Allograft Vasculopathy6) Infection/Nephropathy7) Other Complications

(hypertension, hyperlipidemia,malignancy, diabetes, etc)

9:30 am BREAK

9:45 amSESSION 5:Pulmonary HypertensionThis session will cover the following topics via lectures and panel discussion

1) Classification and overview of pathogenesis

2) Diagnosis and end points forclinical management

3) Physiology and pathophysiol-ogy of the Right Ventricle

4) Managing the potential hearttransplant recipient with araised PVR

5) Treatment of PAH – State ofthe Art Overview

11:45 amCONCLUSION AND ADJOURN

FACULTY AND STEERING COMMITTEE MEMBERSCO-CHAIR: James K. Kirklin, MD, University of Alabama at Birmingham,Birmingham, AL

CO-CHAIR: Mandeep R. Mehra, MD, University of Maryland School of Medicine, Baltimore, MD

Heather J. Ross, MD, FRCPC, Toronto General Hospital, Toronto, CANADA

James B. Young, MD, Cleveland ClinicFoundation, Cleveland, OH

John B. O'Connell, MD, St. Joseph’s Hospital, Atlanta, GA 30342

Francis D. Pagani, MD, PhD, University ofMichigan Hospital, Ann Arbor, MI

Andreas Oliver Zuckermann, MD, University of Vienna, Vienna, AUSTRIA

Roberta C. Bogaev, MD, FACC, Texas HeartInstitute, Houston, TX

Jayan Parameshwar, FRCP, Papworth Hospital, Cambridge, UNITED KINGDOM

Jon Kobashigawa, MD, Cedars Sinai HeartInstitute, Los Angeles, CA

Patricia A. Uber, Pharm.D, University ofMaryland, Baltimore, MD

Paul A. Corris, MB FRCP, Freeman Hospital,Newcastle Upon Tyne, UNITED KINGDOM

Myung H. Park, MD, University of MarylandSchool of Medicine, Baltimore, MD

Allen S. Anderson, MD, University ofChicago Medical Center, Chicago, IL

Anne I. Dipchand, MD, Hospital for SickChildren, Toronto, CANADA

James F. George, PhD, University of Alabama at Birmingham, Birmingham, AL

ADVANCED HEART FAILURE AND CARDIACTRANSPLANTATION CORE COMPETENCIES

INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION

REGISTRATION FORM: ON-LINE REGISTRATION IS ENCOURAGED AND IS AVAILABLE ON THE ISHLT WEBSITE: www.ishlt.org

Last Name: __________________________________________ First Name: ________________________________________ Middle Initial:______

Credential (MD, RN, etc.): __________________________________ Nickname for badge (if desired):__________________________________

Institution/Organization Name for Inclusion on Badge:________________________________________________________________________________

Preferred Mailing Address. Please indicate if this is a home or business address: � Home � Business

Mailing Address: ____________________________________________________________________________________________________

______________________________________________________________________________________________________________________

City: ________________________________________ State:__________ Postal Code:______________ Country: ____________________________

Telephone: __________________________________________________ Fax:________________________________________________________

Email: ________________________________________________

IMPORTANT DO NOT include payment for your hotel deposit with your registration payment.Send this form and payment in full to: ISHLT, 14673 Midway Road, Suite 200, Addison, TX 75001, or fax to 972-490-9499

PAYMENT See instruction #10 for Wire Transfer Instructions. Full payment in US funds only must accompany your registration form. Checks must bemade payable to ISHLT and must be drawn on a US bank. If you prefer to pay by credit card, please complete the following and EITHER mail or fax so that yourcard does not get charged twice.

Credit Card: � VISA � Mastercard � American Express Card Number: ______________________________________________________________

Cardholder Signature:________________________________________________________ CSC Code:*____________ Expiration Date:____________________*CSC (Credit Card Security Code is the 3 digit code on the back of MC/VISA and 4 digit code on front of AMEX.)

Cardholder Name: __________________________________________________________ Card Holder Billing Zip/Postal Code: __________________________(required)

HILTON CH ICAGO • CHICAGO, I L USA • APR IL 21 -24 , 2010Important: See reverse side of this form for instructions and refund/registration policies.

3 0 T H A N N I V E R S A R Y M E E T I N G & S C I E N T I F I C S E S S I O N S

SCIENTIFIC SESSION REGISTRATION Postmarked on or before March 10 Postmarked after March 10 TOTAL

Regular Member � $550 � $650 $ ______________Regular Non-Member† � $825 � $925 $ ______________Allied Health Member* � $450 � $550 $ ______________Allied Health Non-Member† � $725 � $825 $ ______________Student/Resident Member* � $350 � $450 $ ______________Student/Resident Non-Member*† � $475 � $575 $ ______________* See instruction #8† Non-member registration prior to March 10 includes membership in the Society through December 31, 2010.

� Please check here if you wish to decline the membership offer (no refund or reduction of fee).

GALA RECEPTION (1 ticket is included with your registration fee) ________ # of tickets x $75 $ ______________Additional Tickets to Gala Reception for spouses/guests.

JUNIOR FACULTY MENTOR LUNCH � $10 $ ____________Registration is limited to student/resident/fellow members of ISHLT who are registered for the meeting. Limit to first 100 registrants.

ADVANCED HEART FAILURE AND CARDIAC TRANSPLANTATION CORE COMPETENCIES COURSELimited to the first 150 registrants.

Discounted Registration Regular Registration TOTAL(If also registered for the Annual Meeting)

Member � $175 � $250 $ ______________Non-Member � $250 � $325 $ ______________

TOTAL DUE AND ENCLOSED $ ____________

REGISTRATION POLICIES/INSTRUCTIONS FOR COMPLETING THE REGISTRATION FORM:

1. The registration fee includes attendance at all Satellite Symposia, Sunrise Symposia, Plenary Sessions, Concurrent Sessions, Mini Oral Session, Exhibit Hall Opening Reception, coffee breaks, and one ticket to the President’s Gala Reception.

2. You must be registered for the Scientific Sessions in order to attend the Satellite Symposia.

3. DO NOT include payment for your hotel deposit with your registration payment. Payments that in-clude such will be returned to you.

4. For those who register by March 10, the non-member registration fee includes membership in the Societyfrom the date of registration through December 31, 2010. You will be required to complete a membershipapplication in order to activate your membership. Please mark the box provided if you do not wish to accept the offer of membership. Declining the offer will not result in a reduction of the non-member registration fee.

5. DO NOT fax your registration form if you are paying by check or bank draft. Registration forms receivedwithout accompanying payment will not be processed.

6. Registration fees are determined by the date when payment in full is postmarked/faxed. Registration forms sent without payment in full or with invalid credit card information are subject to the registrationfee in effect at the time payment in full is postmarked/faxed or when the correct credit card information is provided.

Individuals whose registration and payment are not RECEIVED by March 24, 2010 must register on-site.

7. Cancellations must be submitted in writing in order to qualify for any refund. For written cancellation notices RECEIVED by March 24, 2010, a full refund of the scientific session fees paid will be given, less a $75 handling fee. For written cancellation notices received on or after March 25, 2010, no refund of any fees will be given. All refunds will be processed after the meeting.

8. The Allied Health rate is available only to nurses, transplant coordinators, pharmacists, social workers, perfusionists, and engineers. The following are excluded: MDs, PhDs, individuals with doctorates, theirequivalents, and pharmaceutical and device company employees/consultants and must register at the fullmember or non-member rate. Non-member allied health registrants must include with their registra-tion forms a letter signed by the chief/dean of their transplant program verifying their employmentand allied health status. Forms submitted without this letter will not be processed.

*The Student/Resident registration rate is available only to residents, fellows, medical students, nursing students, and graduate students. Non-member student/resident registrants must include with their registration forms a letter signed by the chief/dean of their program verifying their training status. Forms submitted without this letter will not be processed.

9. Full payment in US funds only must accompany your registration. Checks must be made payable toISHLT and must be drawn on a US bank. All bank fees incurred for the processing of your payment will be billed to you. IMPORTANT: DO NOT include payment for your hotel deposit with your registration payment. Payments that include such will be returned to you.

10. Wire Transfers must be received by March 24, 2010. There will be an additional fee for wire transfers in the amount of $35 which must be paid by the sender. Please request bank/wire transfer instruc-tions by emailing leeann.mills@ishlt.org.

11. Travel agencies/sponsoring agencies will not be allowed to pick up multiple registrants’ name badges. Only the person registered for the meeting may pick up his/her name badge. No Exceptions.

QUESTIONS???? Call the ISHLT Headquarters Office at 972-490-9495,

or email us at meetings@ishlt.org, or fax us at 972-490-9499.

INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION

HILTON CH ICAGO • CHICAGO, I L USA • APR IL 21 -24 , 2010

3 0 T H A N N I V E R S A R Y M E E T I N G & S C I E N T I F I C S E S S I O N S

*

ISHLT HOUSING FORM:Reservations may be made using this Housing Form or by telephone by calling Hilton Reservations toll free at 877-865-5320, or on the HiltonChicago reservation link http://www.hilton.com/en/hi/groups/personalized/CHICHHH-HLT-20100419/index.jhtml

Please use one form to reserve one room. You may photocopy this form to reserve additional rooms. Reservations forms must be received by theHilton Chicago with one night’s deposit no later than March 29, 2010, or until the block is sold out. No more than 5 rooms may be reserved inthe name of any one individual. If you require more than 5 rooms, please contact the ISHLT Headquarters office for a group reservation form.

1) Name of Hotel Guest: ____________________________________________________________________________________________LAST NAME FIRST NAME MIDDLE INITIAL

Arrival Date:__________________________________________ Departure Date: ______________________________________________

Institution/Company (required):______________________________________________________________________________________

Address: ________________________________________________________________________________________________________

City:________________________________ State:____________ Country: __________________________ Post Code:________________

Phone: __________________________________________________ Fax: ____________________________________________________

Email: ____________________________________________________ HHONORS #: ____________________________________________

Requests: ______________________________________________________________________________________________________

2) Do you require: � Smoking Room � Non-Smoking Room� Special Accommodations:__________________________________________________________________

3) Room Type: Standard Executive Level� Single $225 (1 person) � Single $275 (1 person)� Double $225 (2 people) � Double $275 (2 people)� Triple $250 (3 people) � Triple $300 (3 people)� Quad $275 (4 people) � Quad $325 (4 people)

Note: Rate categories are subject to availability.

4) Preferred Bed: � King Bed � Two Double Beds

5) Please list below any individuals who will be accompanying you and staying in the same room:

Roommate #1: ______________________________________________________________________________________________________LAST NAME / FIRST NAME ARRIVAL DATE DEPARTURE DATE

Roommate #2: ______________________________________________________________________________________________________LAST NAME / FIRST NAME ARRIVAL DATE DEPARTURE DATE

Roommate #3: ______________________________________________________________________________________________________LAST NAME / FIRST NAME ARRIVAL DATE DEPARTURE DATE

6) All reservations must be secured with a deposit in the amount of one night’s lodging and tax. Reservations submitted without a deposit will not be processed.

7) Deposits may be made via credit card or check. Checks must be made payable to the Hilton Chicago and must be drawn on a US Bank. If you prefer to pay by credit card, please complete the following:

Credit Card: � VISA � Mastercard � American Express � Discover � Diners Club

Card Number: ____________________________________________________________ Expiration Date: ____________________________

Card Holder Signature: ____________________________________________Card Holder Name: ______________________________________

Return completed Hotel Reservation Form with required deposit by Monday, March 29, 2010 to: Hilton Chicago, 720 S. Michigan Avenue. Reservation Phone: 877-865-5320 Reservations Fax: 312-663-6528

Cancellation Policy: Notice of cancellation of reservations must be made seven days in advance of the reservation arrival date or the deposit will be forfeited.

INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION

HILTON CH ICAGO • CHICAGO, I L USA • APR IL 21 -24 , 2010

3 0 T H A N N I V E R S A R Y M E E T I N G & S C I E N T I F I C S E S S I O N S

ON-LINE REGISTRATION IS ENCOURAGED AND AVAILABLE

VISIT WWW.ISHLT.ORG

Meet us in Chicago for the International Society of

Heart and Lung TransplantationAnnual Meeting &

Scientific Sessions!

INTERNATIONAL SOCIETY FORHEART AND LUNG TRANSPLANTATION

14673 Midway Road, Suite 200Addison, Texas 75001

tel: 972 490-9495 fax: 972 490-9499email: meetings@ishlt.org web: ishlt.org

201131st ISHLT Annual Meeting and Scientific SessionsHilton San Diego BayfrontSan Diego, CA, USAApril 13-16

201232nd ISHLT Annual Meeting and Scientific SessionsConvention CenterPrague, Czech RepublicApril TBD

F U T U R E I S H L T A N N U A L M E E T I N G S