ChemInform Abstract: A Convenient Synthesis of Methyl 2-Hydroxy-4-oxo-4-(substituted...
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ChemInform 2009, 40, issue 51 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Oxocarboxylic acids and esters Q 0460 A Convenient Synthesis of Methyl 2-Hydroxy-4-oxo-4-(substituted phenyl)bu- tanoates from Malic Acid. — Friedel—Crafts acylation of substituted benzenes with 2-acetoxybutanoyl chloride (II), generated easily from malic acid, affords the key in- termediates of bioactive molecules in an easy manner. — (ZHANG, Y.; KHAN, M. N. A.; GONG, P.; LEE*, Y. S.; Chin. Chem. Lett. 20 (2009) 8, 898-900; Dep. Pharm. Sci., Coll. Pharm., Kyung Hee Univ., Seoul 130-701, S. Korea; Eng.) — R. Simon 51- 099
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Transcript of ChemInform Abstract: A Convenient Synthesis of Methyl 2-Hydroxy-4-oxo-4-(substituted...
www.cheminform.wiley-vch.de
Oxocarboxylic acids and estersQ 0460 A Convenient Synthesis of Methyl 2-Hydroxy-4-oxo-4-(substituted phenyl)bu-
tanoates from Malic Acid. — Friedel—Crafts acylation of substituted benzenes with 2-acetoxybutanoyl chloride (II), generated easily from malic acid, affords the key in-termediates of bioactive molecules in an easy manner. — (ZHANG, Y.; KHAN, M. N. A.; GONG, P.; LEE*, Y. S.; Chin. Chem. Lett. 20 (2009) 8, 898-900; Dep. Pharm. Sci., Coll. Pharm., Kyung Hee Univ., Seoul 130-701, S. Korea; Eng.) — R. Simon
51- 099
ChemInform 2009, 40, issue 51 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
