Chapter 1: Incidence, Prevalence, Patient Characteristics, and Treatment Modalities 2014 A NNUAL D...

Chapter 1: Incidence, Prevalence, Patient Characteristics, and Treatment Modalities 2014 A NNUAL D ATA R EPORT V OLUME 2: E ND -S TAGE R ENAL D ISEASE

Data Source: Reference table D1. Abbreviation: ESRD, end-stage renal disease. vol 2 Figure 1.1 Trends in the number of incident cases of ESRD, in thousands, by modality, in the U.S. population, 1980-2012 Vol 2, ESRD, Ch 12

Data Source: Reference tables A.2(2) and A.2(3). *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease. vol 2 Figure 1.2 Trends in the adjusted* incidence rate of ESRD, per million/year (bars; scale on right), and annual percent change in the adjusted* incidence rate of ESRD (lines; scale on left) in the U.S. population, 1980-2012 Vol 2, ESRD, Ch 13

4 vol 2 Figure 1.3 Map of the adjusted* incidence rate of ESRD, per million/year, by state, in the U.S. population, 2012 Data Source: Reference table A.9, and special analyses, USRDS ESRD Database. *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 15 Data Source: Reference table: A.10, A.11, and Special Analyses, USRDS ESRD Database. *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Listed from lowest to highest rate per million/year. Abbreviations: Af Am, African American; ESRD, end-stage renal disease; Hisp, Hispanic; N Am, Native American. vol 2 Table 1.1 Adjusted* incidence rate of ESRD, per million/year, and percentage distribution of diabetes, race and ethnicity among incident ESRD patients, by ESRD network, 2012 Net- work States in Network Total patients % of total Rate per million/year Mean age % Diabetic RaceEthnicity % White % Af Am % N Am % Asian % Hisp 1CT, MA, ME, NH, RI VT3,6543.2256.464.139.282.414.50.22.89.6 16AK, ID, MT, OR, WA3,3802.9269.361.743.282.46.13.48.07.8 15AZ, CO, NV, NM, UT, WY5,3374.6301.561.147.678.18.38.84.524.3 7FL7,4446.5319.564.239.667.830.00.22.015.4 2NY6,9646.1325.764.143.263.030.50.36.114.3 6NC, SC, GA9,9188.6328.060.640.444.053.70.71.52.3 5MD, DC, VA, WV6,5965.7334.762.539.350.645.90.13.22.7 12IA, KS, MO, NE4,2293.7336.963.340.476.621.00.81.54.5 11MI, MN, ND, SD, WI7,1516.2337.563.239.971.822.72.82.53.7 4DE, PA5,1304.5341.065.041.574.723.70.11.53.8 17N. CA, HI, GUAM, AS5,7925.0358.562.449.056.311.60.631.320.2 8AL, MS, TN6,3105.5364.461.243.051.047.60.40.91.4 3NJ, PR5,0924.4366.763.949.571.524.70.03.638.7 13AR, LA, OK4,6514.1372.461.344.156.138.83.91.13.3 10IL5,2104.5395.563.638.464.730.90.33.912.3 9IN, KY, OH9,1528.0404.063.344.576.622.20.11.12.4 18S. CA8,8167.7420.462.848.872.912.30.513.941.3 14TX9,8008.5426.460.354.773.623.50.22.640.9 All 114,813100.0353.262.544.066.327.41.15.114.8

Vol 2, ESRD, Ch 16 vol 2 Figure 1.4 Trends in (a) ESRD incident cases, in thousands, and (b) adjusted* ESRD incidence rate, per million/year, by age group, in the U.S. population, 1980-2012 Data Source: Reference tables A.1, A.2(2). *Adjusted for sex and race. The standard population is the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease. (a) Incident Cases(b) Incidence Rates

Vol 2, ESRD, Ch 17 vol 2 Figure 1.5 Trends in (a) ESRD incident cases, in thousands, and (b) adjusted* ESRD incidence rate, per million/year, by race, in the U.S. population, 1980-2012 Data Source: Reference tables A.1, A.2(2). *Adjusted for age and sex; the standard population was the U.S. population in 2011. Panel b: ~Estimate shown is imprecise due to small sample size and may be unstable over time. The line for Native Americans has a discontinuity because of unreliable data for that year. Abbreviations: Af Am, African American; ESRD, end-stage renal disease; N Am, Native American. (a) Incident Cases(b) Incidence Rates

Vol 2, ESRD, Ch 18 vol 2 Figure 1.6 Trends in (a) ESRD incident cases, in thousands, and (b) adjusted* ESRD incidence rate, per million/year, by Hispanic ethnicity, in the U.S. population, 1996-2012 Data Source: Reference tables A.1, A.2(3). *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease. (a) Incident Cases(b) Incidence Rates

Vol 2, ESRD, Ch 19 vol 2 Figure 1.7 Trends in (a) ESRD incident cases, in thousands, and (b) adjusted* ESRD incidence rate, per million/year, by primary cause of ESRD, in the U.S. population, 1980-2012 (a) Incident Cases(b) Incidence Rates Data Source: Reference tables A.1, A.2(2). *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 110 vol 2 Figure 1.8 Trends in the sex-adjusted incidence rate* of ESRD due to diabetes as the primary cause, per million/year, by age, race, and ethnicity, for black/African Americans, in the U.S. population, 1980-2012 Data Source: Special analyses, USRDS ESRD Database. *Rates are based on three-year rolling averages, and they are adjusted for sex. The standard population is the U.S. population in 2011. Abbreviations: Af Am, African American; ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 111 vol 2 Figure 1.8 Trends in the sex-adjusted incidence rate* of ESRD due to diabetes as the primary cause, per million/year, by age, race, and ethnicity, for whites, in the U.S. population, 1980-2012 Data Source: Special analyses, USRDS ESRD Database. *Rates are based on three-year rolling averages, and they are adjusted for sex. The standard population is the U.S. population in 2011. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 112 vol 2 Figure 1.8 Trends in the sex-adjusted incidence rate* of ESRD due to diabetes as the primary cause, per million/year, by age, race, and ethnicity, for Hispanics, in the U.S. population, 1980-2012 Data Source: Special analyses, USRDS ESRD Database. *Rates are based on three-year rolling averages, and they are adjusted for sex. The standard population is the U.S. population in 2011. Abbreviations: Hisp, Hispanic; ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 113 vol 2 Figure 1.9 Trends in the sex-adjusted incidence rate* of ESRD due to hypertension as the primary cause, per million/year, by age, race, and ethnicity, for blacks/African Americans, in the U.S. population, 1980-2012 Data Source: Special analyses, USRDS ESRD Database. *Rates are based on three-year rolling averages, and they are adjusted for sex. The standard population is the U.S. population in 2011. Abbreviations: Af Am, African American; ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 114 vol 2 Figure 1.9 Trends in the sex-adjusted incidence rate* of ESRD due to hypertension as the primary cause, per million/year, by age, race, and ethnicity, for whites, in the U.S. population, 1980-2012 Data Source: Special analyses, USRDS ESRD Database. *Rates are based on three-year rolling averages, and they are adjusted for sex. The standard population is the U.S. population in 2011. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 115 vol 2 Figure 1.9 Trends in the sex-adjusted incidence rate* of ESRD due to hypertension as the primary cause, per million/year, by age, race, and ethnicity, for Hispanics, in the U.S. population, 1980-2012 Data Source: Special analyses, USRDS ESRD Database. *Rates are based on three-year rolling averages, and they are adjusted for sex. The standard population is the U.S. population in 2011. Abbreviations: Hisp, Hispanic; ESRD, end-stage renal disease.

Data Source: Reference table D.1. Abbreviation: ESRD, end-stage renal disease. vol 2 Figure 1.10 Trends in the number of prevalent cases of ESRD, in thousands, by modality, in the U.S. population, 1980-2012 Vol 2, ESRD, Ch 116

Data Source: Reference table: B.2(2), and B.2(3). *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease. vol 2 Figure 1.11 Trends in the adjusted* ESRD prevalence per million (bars; scale on left), and annual percent change in adjusted* prevalence of ESRD (lines; scale on right), in the U.S. population, 1980-2012 Vol 2, ESRD, Ch 117

Vol 2, ESRD, Ch 118 vol 2 Figure 1.12 Map of the adjusted* prevalence of ESRD per million, by state, in the U.S. population, 2012 Data Source: Reference table B.9, and special analyses, USRDS ESRD Database. *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Abbreviation: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 119 Data Source: Special analyses, USRDS ESRD Database. *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Listed from lowest to highest prevalence per million. Abbreviations: Af Am, African American; ESRD, end-stage renal disease; Hisp, Hispanic; N Am, Native American. vol 2 Table 1.2 Adjusted* prevalence of dialysis, per million, and percentage distribution of diabetes, race, and ethnicity among prevalent dialysis patients, by ESRD network, 2012 Race Ethnicity NetworkStates in Network Total patients % of total Prevalence per million Mean age % Diabetic % White % Af Am % N Am % Asian % Hisp 16AK, ID, MT, OR, WA 11,1872.777261.944.775.99.54.010.311.0 1CT, MA, ME, NH, RI VT 12,4223.083164.940.274.221.40.33.411.7 15AZ, CO, NV, NM, UT, WY 19,1354.792961.752.670.211.213.25.031.6 12IA, KS, MO, NE 13,5313.396162.941.566.130.91.11.75.8 11MI, MN, ND, SD, WI 24,1385.91,04863.141.761.032.73.22.94.7 9IN, KY, OH 27,9976.91,22462.544.363.535.20.11.02.8 4DE, PA 17,2644.21,23763.541.461.036.60.11.95.2 7FL 24,6616.01,24162.940.754.143.00.32.117.9 17N. CA, HI, GUAM, AS 21,6965.31,29562.851.149.015.40.833.723.6 2NY 26,6166.51,32063.541.249.941.40.46.816.6 10IL 17,6164.31,34262.739.653.442.30.23.814.8 3NJ, PR 17,4364.31,35063.547.359.533.40.13.937.7 13AR, LA, OK 16,0413.91,38760.143.540.154.04.41.33.7 5MD, DC, VA, WV 23,7705.81,40161.939.435.660.40.33.14.0 18S. CA 34,8508.51,42962.649.970.015.60.413.548.6 14TX 38,7129.51,44460.354.066.530.20.32.345.8 6NC, SC, GA 38,7069.51,54460.340.628.968.70.71.32.9 8AL, MS, TN 22,6655.61,55960.241.535.563.20.50.61.2 All 408,711100.01,25162.144.654.937.61.45.417.9

Vol 2, ESRD, Ch 120 Data Source: Special analyses, USRDS ESRD Database. *Adjusted for age, sex, and race. The standard population was the U.S. population in 2011. Listed from lowest to highest prevalence per million. Abbreviations: Af Am, African American; ESRD, end-stage renal disease; Hisp, Hispanic; N Am, Native American. vol 2 Table 1.3 Adjusted* prevalence of kidney transplant patients, per million, and percentage distribution of diabetes, race, and ethnicity among prevalent transplant patients, by ESRD network, 2012 RaceEthnicity NetworkStates in Network Total patients % of total Prevalence per million Mean age % Diabetic% White % Af Am % N Am % Asian % Hisp 13AR, LA, OK5,5543.0482.152.224.064.030.92.62.03.5 7FL9,6495.2482.354.922.371.123.00.53.419.5 14TX13,0897.0482.351.425.375.317.70.44.037.5 16AK, ID, MT, OR, WA7,2053.9498.353.322.983.45.21.88.67.5 6NC, SC, GA12,5546.7501.852.522.855.040.80.82.33.4 15AZ, CO, NV, NM, UT, WY10,4365.6506.252.928.383.05.85.44.423.4 18S. CA12,9857.0525.651.719.873.99.90.413.341.5 8AL, MS, TN7,8044.2540.251.921.460.637.60.21.31.5 9IN, KY, OH12,9376.9565.753.024.879.717.60.11.62.4 1CT, MA, ME, NH, RI VT8,5384.6568.153.920.282.511.40.33.88.6 2NY12,1536.5587.453.421.364.823.20.56.918.2 17N. CA, HI, GUAM, AS9,7645.2589.853.322.161.88.90.724.624.4 12IA, KS, MO, NE8,3284.5593.753.323.882.013.91.42.25.2 4DE, PA8,8084.7626.054.623.074.820.50.22.64.2 3NJ, PR7,2553.9629.753.623.364.020.30.25.729.1 5MD, DC, VA, WV11,0465.9647.253.622.055.138.00.34.84.6 10IL9,1914.9687.752.823.369.422.60.44.914.7 11MI, MN, ND, SD, WI16,2568.7707.753.926.379.914.01.93.5 All 186,303100.0562.453.023.070.619.61.05.714.5

Vol 2, ESRD, Ch 121 vol 2 Figure 1.13 Trends in (a) prevalent ESRD cases and (b) the adjusted* prevalence of ESRD, per million, by age group, in the U.S. population, 1980-2012 (a) Prevalent Cases(b) Prevalence per million Data Source: Reference tables B.1, B.1(2). *Point prevalence on December 31 of each year; Adjusted for sex and race; The standard population was the U.S. population in 2011 ESRD patients. Abbreviation: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 122 vol 2 Figure 1.14 Trends in (a) prevalent ESRD cases and (b) the adjusted* prevalence of ESRD, per million, by race, in the U.S. population, 1980-2012 (a) Prevalent Cases(b) Prevalence per million Data Source: Reference tables B.1, B.1(2). *Point prevalence on December 31 of each year; Adjusted for age and sex; The standard population was the U.S. population in 2011 ESRD patients. Panel b: ~Estimate shown is imprecise due to small sample size and may be unstable over time. The line for Native Americans has a discontinuity because of unreliable data for that year. Abbreviations: Af Am, African American; ESRD, end-stage renal disease; N Am, Native American.

Vol 2, ESRD, Ch 123 vol 2 Figure 1.15 Trends in (a) prevalent ESRD cases and (b) the adjusted* prevalence of ESRD, per million, by ethnicity, in the U.S. population, 1980-2012 (a) Prevalent Cases(b) Prevalence per million Data Source: Reference tables B.1, B.1(3). *Point prevalence on December 31 of each year; Adjusted for age, sex, and race; The standard population was the U.S. population in 2011 ESRD patients. Abbreviation: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 124 vol 2 Figure 1.16 Trends in (a) prevalent ESRD cases and (b) adjusted* prevalence of ESRD, per million, by primary cause of ESRD, in the U.S. population, 1980-2012 (a) Prevalent Cases(b) Prevalence per million Data Source: Reference tables B.1, B.1(2). *Point prevalence on December 31 of each year; Adjusted for age, sex, and race, The standard population was the U.S. population in 2011 ESRD patients. Abbreviation: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 125 HD PD Tx N%N%N% Age 0-195060.53493.82458.7 20-4410,37510.51,65018.066123.6 45-6438,26838.73,95243.11,35548.3 65-7424,52824.81,90020.748517.3 75+25,27725.51,32414.4572.0 Sex Male56,84757.45,19756.61,61257.5 Female42,10742.63,97843.41,19142.5 Race White65,43066.16,41569.92,28881.6 Black/African Am28,65929.02,13723.329210.4 Native American1,1391.2870.9291.0 Asian3,7263.85365.81946.9 Ethnicity Hispanic13,70213.81,25113.642015.0 Non-Hispanic85,25286.27,92486.42,38385.0 Primary cause of ESRD Diabetes43,92244.43,78341.244115.7 Hypertension29,11129.42,37325.92579.2 Glomerulonephritis6,8897.01,38715.155319.7 Cystic kidney1,5511.64765.242915.3 Other urologic4100.4610.7541.9 Other Cause10,76210.96827.450117.9 Unknown/missing6,3096.44134.556820.3 All98,954100.09,175100.02,803100.0 vol 2 Table 1.4 Number and percentage of incident cases of hemodialysis (HD), peritoneal dialysis (PD), and transplantation (Tx) by age, sex, race, ethnicity, and primary ESRD diagnosis, in the U.S. population, 2012 Data Source: Special analyses, USRDS ESRD Database. Abbreviation: African Am, African American; ESRD, end-stage renal disease.

Data Source: Reference table: D.1. vol 2 Figure 1.17 Trend in the number of incident ESRD patients using home hemodialysis, in thousands, by type of therapy, in the U.S. population, 1980-2012 Vol 2, ESRD, Ch 126

Vol 2, ESRD, Ch 127 HDPDTx N%N%N% Age 0-191,1340.38982.24,9572.8 20-4449,84312.48,18720.239,96522.7 45-64167,49941.618,13744.789,87651.1 65-7495,88923.88,28420.432,47518.5 75+88,14921.95,09912.68,7054.9 Sex Male226,20556.221,96854.1104,65459.5 Female176,30943.818,63745.971,32440.5 Race White221,88755.126,69065.7128,46873.0 Black/African Am153,26438.110,53425.935,62820.2 Native American5,8391.54761.21,7551.0 Asian21,5245.32,9057.210,1275.8 Ethnicity Hispanic68,71017.15,91514.635,46720.2 Non-Hispanic333,80482.934,69085.4140,51179.8 Primary cause of ESRD Diabetes178,01244.214,12034.840,68823.1 Hypertension116,26028.910,52825.927,78515.8 Glomerulonephritis43,52110.87,93119.548,98027.8 Cystic kidney9,5432.41,8954.717,4639.9 Other urologic3,0520.83690.93,5152.0 Other Cause32,5138.13,6609.020,30611.5 Unknown/missing19,6134.92,1025.217,2419.8 All402,514100.040,605100.0175,978100.0 vol 2 Table 1.5 Number and percentage of prevalent cases of hemodialysis (HD), peritoneal dialysis (PD), and transplantation (Tx) by age, sex, race, ethnicity, and primary ESRD diagnosis, in the U.S. population, 2012 Data Source: Special analyses, USRDS ESRD Database. Abbreviation: African Am, African American; ESRD, end-stage renal disease.

Data Source: Reference table: D.1. December 31 prevalent ESRD patients; peritoneal dialysis consists of CAPD and CCPD only. Abbreviations: CAPD, continuous ambulatory peritoneal dialysis; CCPD, continuous cycler peritoneal dialysis; ESRD, end-stage renal disease. vol 2 Figure 1.18 Trend in the number of prevalent ESRD patients using home dialysis, in thousands, by type of therapy, in the U.S. population, 1980-2012 Vol 2, ESRD, Ch 128

Vol 2, ESRD, Ch 129 vol 2 Figure 1.19 Trend in the distribution of payer type among incident ESRD patients using hemodialysis, 1978-2012 (a) Hemodialysis Data Source: Special analyses, USRDS ESRD Database. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 130 vol 2 Figure 1.19 Trend in the distribution of payer type among incident ESRD patients using peritoneal dialysis, 1978-2012 (b) Peritoneal Dialysis Data Source: Special analyses, USRDS ESRD Database. Peritoneal dialysis consists of CAPD and CCPD only. Abbreviations: CAPD, continuous ambulatory peritoneal dialysis; CCPD, continuous cycler peritoneal dialysis; ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 131 vol 2 Figure 1.19 Trend in the distribution of payer type among incident ESRD patients with transplants, 1978-2012 (c) Transplant Data Source: Special analyses, USRDS ESRD Database. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 132 vol 2 Figure 1.20 Trend in the distribution of payer type among prevalent ESRD patients using hemodialysis, 1978-2012 (a) Hemodialysis Data Source: Special analyses, USRDS ESRD Database. Point prevalence on December 31 of each year. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 133 vol 2 Figure 1.20 Trend in the distribution of payer type among prevalent ESRD patients using peritoneal dialysis, 1978-2012 (b) Peritoneal Dialysis Data Source: Special analyses, USRDS ESRD Database. Point prevalence on December 31 of each year; Peritoneal dialysis consists of CAPD and CCPD only. Abbreviations: CAPD, continuous ambulatory peritoneal dialysis; CCPD, continuous cycler peritoneal dialysis; ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 134 vol 2 Figure 1.20 Trend in the distribution of payer type among prevalent ESRD patients with transplants, 1978-2012 (c) Transplant Data Source: Special analyses, USRDS ESRD Database. Point prevalence on December 31 of each year. Abbreviations: ESRD, end-stage renal disease.

Vol 2, ESRD, Ch 135 None0-12 mo.>12 mo.* % of patients41.330.827.9 Mean Age61.662.763.7 Age 0-1934.331.234.4 20-2447.629.023.3 45-6442.730.926.4 65-7438.731.330.0 75+38.930.730.3 Sex Male39.131.829.1 Female38.832.328.9 Race White37.236.526.4 Black42.132.225.7 Native Amer.45.030.224.7 Asian39.630.829.6 Hispanic ethnicity Yes47.730.921.4 No39.731.029.3 None0-12 mo.>12 mo.* Vascular Access Fistula10.536.053.5 Catheter49.330.120.6 Graft19.936.843.3 ESA use3.842.553.7 Dietary care0.745.753.5 eGFR at RRT start*

Chapter 1: Incidence, Prevalence, Patient Characteristics, and Treatment Modalities 2014 A NNUAL D...

Documents

Transcript of Chapter 1: Incidence, Prevalence, Patient Characteristics, and Treatment Modalities 2014 A NNUAL D...