BRCA Hereditary Cancer MASTR Plus · preparation kits and software, for the detection of germline...
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BRCA Hereditary Cancer MASTR Plus For Next-Generation Sequencing human
Transcript of BRCA Hereditary Cancer MASTR Plus · preparation kits and software, for the detection of germline...
BRCA Hereditary Cancer MASTR Plus
For Next-Generation Sequencing
human
VA
RIA
NT
S IN
25
GEN
ES
PLU
S T
HE 3’UTR
OF EP
CAM
MASTR Reporter Analysis
MASTR ReporterAnalysis Results
FASTQ Files
Create daily back-upof Data Server
Lab Professional
MASTR ReporterAnalysis Results
FASTQ Files
Secure Internet protocol Private Network
Data Server Back-up Server
MASTR Reporter
Encrypted connection Encrypted Data storage
Software is ISO62304 compliant.
DATA SECURITY AND STORAGE
Data security and storage
Read pile-up views
Approve sample
Create analysis report
Quality control
Quality parameter
Context valueValue
Graphical indication of value
Variant calling
MASTR REPORTER*
PTEN
CDH1
FAM175A
MEN1
Pancreas
Parathyroidglands
Kidneys
Endometrialglands
Colon
Stomach
BARD1
BRCA1
BRCA2
BRIP1
RAD51C
RAD51D
TP53
MRE11A
RAD50
NBN
Breasts
Ovarians
ATM
PALB2
STK11
MUTYH
CHEK2
BLM
XRCC2
EPCAM*
PMS2
MSH2
MSH6
MLH1
*3'UTR of EPCAM
OPTIMIZED CNV CALLING ALGORITHM
BRCA Hereditary Cancer MASTR Plus
Simple, reliable, easy-to-use, molecular research assay, including library
preparation kits and software, for the detection of germline variants in BRCA1,
BRCA2 and other important genes.
ADDED VALUES
• Simple workflow from DNA sample to report
• All software parameters are optimized specifically for MASTR kits
• Layered information which allows deep analysis of data
• Metrics and analytics for traceability and audits
• Support of your validation
• Integrated quality control: measure, monitor and optimize your complete workflow
• Fast and reliable variant calling: SNVs, indels and CNVs
Testkits & Reporters
Continuous Support
Proof ofPrinciple
EnablingServices
Workshops & Training
ExpertSupport Toolbox
human onco prenatal
ClarigoReporter
MASTRReporter
OUR SOLUTIONS
v.1708 - EUFor Research Use Only. Not for use in diagnostic procedures.
Our ready-to-use assays analyze the genes that matter in a simple,
efficient and reliable manner.
Our Reporter software ensures correct analysis and enables quality
control from initial sample to result.
Our Expert Support Team help you to set up our tests and secure
your results.
We guide your lab towards better results. Every step of the way.
WORKFLOW
Multiplex PCR Universal PCR SEQUENCING
DATA ANALYSIS
Pooling & Clean up
NGS
Sample Preparation
Quality Control
Genes Workflow Sample Type Amplicon length
BRCA HC MASTR Plus + MASTR Reporter BRCA HC MASTR Plus
25 + 3’UTR EPCAM MASTR Plus Blood 232 - 430
* Somatic applications not yet available on the MASTR Reporter
Multiplicom N.V. [ a ] Galileïlaan 18, B-2845 Niel, Belgium [ w ] www.agilent.com [ e ] [email protected] [ t ] +32 3 289 14 00 [ f ] +32 3 400 23 16
