Bone Metabolism
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Transcript of Bone Metabolism
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Bone Metabolism
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Rickets• Rickets (children) – failure of
mineralization of the epiphyseal plate• Related to lack of Vitamin D
– Dietary• Poverty• Third world countries
– Sunlight exposure• Northern latitudes• Sun screen
– Metabolic failure
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Renal Osteodystrophy
• Osteomalacia (low bone density) – failure of mineralization of osteoid
• Osteosclerosis (high bone density) – dense bones– Abnormal resorption of mineral– Abnormal deposition of mineral
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Renal Rickets• Child• Zone of
provisional calcification is deficient
• Metaphyses irregularly mineralized, widened and cupped
• Fracture of distal fibulaImages courtesy Nancy Fitzgerald, MD, Texas Children’s Hospital
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Rickets
• Widening of the ribs at the costal-chondral junction
• Known clinically as Rachitic Rosary
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Rickets
Images courtesy Nancy Fitzgerald, MD, Texas Children’s Hospital
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Rickets
• Widened metaphysis with fraying
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Rickets
• Wrist film• Another patient• Cupping and
fraying of metaphyses
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Treated Rickets
• Same patient after 3 months of Vitamin D
• Improved appearance with well defined slightly undulating metaphysis