Biomedical Imaging Using a Barcode Scanner
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Transcript of Biomedical Imaging Using a Barcode Scanner
Biomedical Imaging Using a Barcode ScannerBy: Nidhi Khurana Rajesh Satpathy
Challenge in biomedical imaging
• Picture of current biomedical imaging system
Challenge: Can we build a low cost biomedical imaging system?
Wojtkowski, M., Applied Optics 49, D30-D61, 2010.
Challenge in biomedical imaging
• Picture of current biomedical imaging system
Challenge: Can we build a low cost biomedical imaging system?
Wojtkowski, M., Applied Optics 49, D30-D61, 2010.
Challenge in biomedical imaging
• Picture of current biomedical imaging system
Challenge: Can we build a low cost biomedical imaging system?
Use a barcode scanner
Wojtkowski, M., Applied Optics 49, D30-D61, 2010.
Near infrared light
Depth scanning
http://cdn.wn.com/pd/dc/9d/cfc0915c804ff4dbb70ccee3feed_grande.jpg
Cross sections
Optical Coherence Tomography (OCT)
Galvonometer
Barcode Scanner
Barcode Scanner
Barcode Scanner
• 2 rows of 640 photon receptors (sensors)
• Sensors
– Aligned linearly
– Measure the light intensity
• Information sent to a processing system
– Light intensity translates into an image
Barcode Scanner Versus CCD Camera
Barcode Scanner Versus CCD Camera
Ratio of pixel size to amount of total light received by the pixel
Pixel size (µm)
Barcode scanner
CCD
Specified pixel separation and focal length affecting image resolution
Specified pixel separation and focal length affecting image resolution
Specified pixel separation and focal length affecting image resolution
Specified pixel separation and focal length affecting image resolution
He-Ne
SLED
IS90/10
L2M4
Scan Mirrors
Array Detector
PBS
M2
M1
M5
L3L1
PC
PC
Sample
M3
Experimental Setup
Spectrometer Barcode Scanner
Spectrometer
1 mm
Achene
Achene Cross sections
Achene
Barcode scanner in vivo image of achene
Microscopic image of strawberry
1 mm
Cell structure
1 mm
Possible necrotizing tissue
Void channel
1 mm
Comparison of CCD and Barcode ScannersConclusion
CCD Camera Barcode Scanner
• High resolution • Cheap
• High sensitivity
• Efficient
• Easy to use
CCD Camera Barcode Scanner
• Expensive
• Complex circuitry
• Slower image acquisition
• Low refresh rate
Pros
Cons
Future Experiments
Mobilization to real device that can be used in hospitals.
Acknowledgement
Dr. Ping Yu, Associate Professor of Physics,
University of Missouri-Columbia
Dr. H.R. Chandrasekhar, Professor of
Physics, University of Missouri-Columbia