Annual Tuberculosis Report - Illinois · Illinois Tuberculosis Control Report 2001-2005...

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State of Illinois Rod R. Blagojevich, Governor Department of Public Health Eric E.Whitaker, M.D., M.P.H., Director Annual Tuberculosis Report - Illinois 2005

Transcript of Annual Tuberculosis Report - Illinois · Illinois Tuberculosis Control Report 2001-2005...

State of IllinoisRod R. Blagojevich, Governor

Department of Public HealthEric E. Whitaker, M.D., M.P.H., Director

Annual Tuberculosis Report - Illinois2005

Annual Tuberculosis Report Illinois 2005

Illinois Department of Public Health Eric E. Whitaker M.D., M.P.H., Director

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TABLE OF CONTENTS Page

1 Introduction..................................................................................................................................... 1 Executive Summary ........................................................................................................................ 2 Table 1 Tuberculosis Cases by Jurisdiction and Regions, 2004-2005.............................. 5 Appendix A – Illinois Data Summary ............................................................................................ 6 Table A1 Tuberculosis Cases reported between 2001 and 2005 by Jurisdiction ................ 6 Table A2 Tuberculosis Cases and Rates (per 100,000 Population), Illinois, 2001-2005 .... 8 Figure A1 TB Morbidity, Number of Cases, Illinois, 1980-2005......................................... 9 Figure A2 Distribution of Foreign-born Tuberculosis Cases, Illinois, 2001-2005 ............... 9 Table A3 Number of Foreign-born Tuberculosis Cases (% of total cases), Illinois, 2001-

2005.............................................................................................................................. 9 Table A3 Number of Foreign-born Tuberculosis Cases (% of total cases), Illinois, 2001-

2005............................................................................................................................ 10 Table A4 Tuberculosis Cases, by Race/Ethnicity, Illinois, 2001-2005 ............................. 10 Table A5 Tuberculosis Cases, by Race/Ethnicity, Illinois, 2005 ...................................... 11 Table A6 Tuberculosis Cases, by Age Group, Illinois, 2001-2005 ................................... 12 Table A7 Tuberculosis Cases, by Age Group, Rates per 100,000 Population, Illinois,

2001-2005 .................................................................................................................. 12 Table A8 MDR1 and Isoniazid2 Drug Resistance in Culture Positive Cases, Illinois, 2001-

2005............................................................................................................................ 13 Table A9 Tuberculosis Cases, by Directly Observed Therapy (DOT), Illinois, 2000-2004

14 Table A10 HIV and TB, 2001-2005 .................................................................................... 14 Table A11 Tuberculosis Cases, by Risk Factors, 2001 – 2005 ........................................... 15 Table A12 Tuberculosis Cases by Verification Criteria, 2001-2005................................... 15 Table A13 Tuberculosis Cases by Country of Origin, 2001-2005 ...................................... 16 Appendix B - References .............................................................................................................. 17

Tuberculosis Case Definition for Public Health Surveillance .................................................. 17 Recommendations for Counting Reported Tuberculosis Cases................................................ 17

Appendix C – TB Regions............................................................................................................ 18

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Illinois Tuberculosis Control Report 2001-2005 Introduction Tuberculosis (TB) is a reportable disease in Illinois (suspect and confirmed cases). The sooner cases are reported to the local TB control authority, the sooner their personnel can begin investigations which may interrupt transmission of TB in the community. Delays in reporting may contribute to the spread of TB. The U.S. Centers for Disease Control and Prevention (CDC) has set national objectives to guide elimination of TB in the United States. Progress has been made toward meeting these objectives in Illinois (Table A1). In 2005, Illinois reported 596 TB cases and ranked fifth in the United States among states for the total number of cases reported (California 2,900; Texas 1,535; New York 1,294; and Florida 1,094). Illinois is among five states reporting the largest increases in the number of TB cases between 2004 and 2005. The states with the largest increases were Ohio (+41), South Carolina (+28), Illinois (+27), Virginia (+26) and Florida (+20). The incidence of TB reported by local Illinois TB authorities ranges from very low incidence (<1 case per year) of disease in rural counties, to high incidence (>400 cases per year) in the Chicago metropolitan area. The Illinois Department of Public Health TB Section is responsible for statewide surveillance, management of the Illinois TB case registry, and oversight of TB prevention and control activities conducted by local TB control authorities (local programs). The section continues to work with local TB control authorities to ensure accurate and timely reporting of the disease in Illinois. Surveillance data is used to direct public health efforts to identified high risk groups and geographic locations. Section staff assists local programs through the provision of Directly Observed Therapy (DOT) grants, assessment and identification of local problems, planning appropriate interventions, assistance with outbreaks, orientation and training of local staff, and promoting and facilitating networking with other programs. This report provides an overview of statewide TB morbidity. For more detailed information on the TB incidence for Illinois jurisdictions and the city of Chicago please refer to the following resources: National level detailed surveillance reports can be obtained from the CDC at: Division of Tuberculosis Elimination - Surveillance Reports Detailed surveillance report for the city of Chicago can be obtained at: Chicago Department of Public Health - Tuberculosis Morbidity Report Archive.

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Figure 1. Reported TB Cases and Rates Illinois, 1995-2005

0200400600800

10001200

1995

1996

1997

1998

1999

2000

2001

2002

2003

2004

2005

Tota

l Cas

es

0

2

4

6

8

10

Rat

es/1

00,0

00

Total Rate

Executive Summary This is the first time in nine years that Illinois has observed an increase in the total number of tuberculosis (TB) cases (Figure 1). During 2005, a total of 596 TB cases were reported, representing an increase of 4.7 percent above the 569 cases reported in 2004. The 2005 case rate for Illinois is 4.7 cases per 100,000 population, which remains below the 2005 national rate of 4.8 per hundred-thousand population. In 2005, the Suburban Cook County TB Sanitarium District reported 120 TB cases, 65 percent of which were foreign-born, compared with 91 cases, 58 percent of which were foreign-born, reported in 2004, representing an increase of 31.9 percent (Table 1 and Table A3). The greatest increase was reported among the foreign-born, particularly those from India. Twenty four cases were reported born in India in 2005 up from 13 cases reported in 2004. (The Suburban Cook County TB Sanitarium District reports cases from Cook County, outside the city of Chicago.) The Chicago TB Program reported 333 TB cases in 2005 compared with 308 cases in 2004, representing an increase of 8.1 percent. There was an increase of 31.8 (N=24) foreign-born cases and a 14.4 percent (N=15) increase among the U.S.-born, black non-Hispanic group. Overall, Chicago did observe a 11.9 percent decline in number of cases and the rate of TB decreased from 13.1 per 100,000 population in 2001 to 11.5 cases per 100,000 population in 2005 (Figure A1 and Table A2). The increase of cases in Chicago and suburban Cook County was offset by a decrease in cases of 17.6 percent (N=27) reported in Illinois outside of Cook County (Table 1). The largest decrease of cases outside of Cook County was reported in the white non-Hispanic population, which decreased 30.4 percent (N=14), and the Hispanic group decreased 22.9 percent (N=11). DuPage County reported the largest decrease in the number of cases from 47 cases in 2004 to 29 cases in 2005. In 2005, 44.8 percent (N=267) cases were foreign-born, coming from 43 countries. Mexico (N=69), India (N=56) and the Philippines (N=32) accounted for 58.8 percent of all foreign-born cases reported (Figure 2). The percentage of foreign-born

Figure 2. Countries of Birth forForeign-born TB Cases in Illinois, 2005

Others24%

Korea, Rep. of3%

China4%

Poland5%

Vietnam3%

Philippines12%

Ethiopia3% India

21%

Mexico25%

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cases increased from 21.0 percent (N=204) in 1995 to 44.8 percent (N=267) in 2005 (Figure 3). Among cases reported in 2005 within Illinois and outside of Chicago, 63.1 percent (N=166) were foreign-born. Among all cases reported between 2001 and 2005, 36.5 percent were black non-Hispanic, 23.4 percent Hispanic, 22.7 percent Asian and 16.3 percent white non-Hispanic. During this same period, the percentage of Hispanic cases increased from 21.1 percent to 23.1 percent and Asian cases increased from 20.5 percent to 25.3 percent, while percentage of white and black non-Hispanic cases declined from 18.2 percent to 14.3 percent and 39.9 percent to 36.6 percent respectively. In 2005, the non-Hispanic black group reported the largest number of cases (N=218) among all the race/ethnicity categories (Table A4). Illinois demographic data shows that, from 2001 to 2005, the highest percentage (35.2 percent), was reported among the 25 to 44 year old age group, whereas the highest rates per 100,000 persons was recorded among the 45 to 64 and 65 and older age groups (Tables A6 and A7). During this same period, cases were divided 57.9 percent male (N=345) to 42.1 percent female (N=251). The rate of cases 18 to 64 years old reporting to be unemployed in the past 24 months increased from 39.9 percent in 2001 to 45.5 percent in 2005. Examining race and ethnicity data among cases reported in 2005 by region of the state yielded considerable differences. For example, Asians accounted for 37.3 percent of cases (N=98) in Illinois outside of Chicago but only 15.9 percent of cases (N=53) in the city of Chicago. During 2005, black non-Hispanics accounted for 49.8 percent of the cases (N=166) in the city of Chicago but only 19.8 percent of cases (N=52) in Illinois outside of Chicago and only 15.4 percent of cases (N=22) in Illinois outside of Cook County (Table A5). Recognizing these differences helps to target resources for local TB elimination efforts. Among all cases reported in 2005, 72.7 percent (N=433) were pulmonary only, 24.3 percent (N=145) extra-pulmonary and 3.0 percent both (N=18). No multi-drug resistant (MDR) cases were reported after initial drug susceptibility in 2005. Previously 1.2 percent (5 of 411 tested) cases reported to be MDR in 2004 (Table A8). Between 2001 and 2005, there were 1,119 TB cases ages 25 to 44. Of these, 73 percent (N=817) reported a valid HIV status and 12.5 percent (N=140) were HIV-positive. During this five-year period, reporting of HIV status for TB cases in this age group improved from a low of 64.2 percent in 2001 to a high of 84.2 percent in 2005 (Table A10). For all ages, the total number of HIV positive TB cases was 235 (7.4 percent). Among the 7,917 AIDS cases reported to the

Figure 3. Percentage TB CasesForeign-born vs. U.S.-born Illinois,

1995-2005

0%

20%

40%

60%

80%

100%

19951996199719981999200020012002200320042005

U.S.-bornForeign-born

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Illinois Department of Public Health (IDPH) during 2001-2005, TB (pulmonary and/or extra-pulmonary) was diagnosed in 223 (2.8 percent) of the cases.

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Table 1 Tuberculosis Cases by Jurisdiction and Regions, 2004-2005 Jurisdiction 2005 2004 % Change

Illinois 596 569 +4.7 Illinois Outside of Chicago (downstate)

263 261 +0.7

Illinois Outside Cook County 143 170 -17.6 City of Chicago 333 308 +8.1 Suburban Cook County 120 91 +31.9 Champaign County 6 3 +100.0 DuPage County 29 47 -38.3 Kane County 10 13 -23.0 Lake County 30 24 +25.0 McHenry County 2 7 -71.4 Madison County 7 6 +16.7 St. Clair County 2 5 -60.0 Sangamon County 2 5 -60.0 Will County 18 15 +20.0 Williamson County 0 3 -300.0 Winnebago County 7 9 -22.2

IDPH Regions Rockford 12 15 -20.0 Peoria 7 5 +40.0 Edwardsville 11 22 -50.0 Marion 7 17 -58.8 Champaign 14 3 -366.7 West Chicago 91 108 -15.7 Chicago (Cook) 453 399 +13.5

TB Regions* North 83 107 -22.4 Central 38 24 +58.3 South 21 39 -46.2 * TB Regions are defined in appendix D.

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Appendix A – Illinois Data Summary Table A1 Tuberculosis Cases reported between 2001 and 2005 by Jurisdiction COUNTY 2001 2002 2003 2004 2005 Total Illinois, Total 707 680 633 569 596 3,185

ADAMS 0 0 1 0 0 1

ALEXANDER 3 0 0 0 0 3

BOND 0 0 0 0 0 0

BOONE 0 1 1 2 1 5

BROWN 0 0 0 0 0 0

BUREAU 0 0 0 0 0 0

CALHOUN 0 0 0 0 0 0

CARROLL 0 0 0 0 0 0

CASS 0 0 0 0 2 2

CHAMPAIGN 10 10 4 3 6 33

CHRISTIAN 0 1 0 0 0 1

CLARK 0 0 0 0 1 1

CLAY 0 0 0 2 0 2

CLINTON 0 0 0 0 0 0

COLES 0 0 0 0 0 0

COOK 518 512 462 399 453 2,344

CHICAGO 378 382 339 308 333 1,740

SUBURBAN COOK 140 130 123 91 120 604

CRAWFORD 0 0 0 1 0 1

CUMBERLAND 0 0 0 0 0 0

DEKALB 7 2 1 2 4 16

DEWITT 0 0 0 0 0 0

DOUGLAS 0 0 0 0 0 0

DUPAGE 48 32 62 47 29 218

EDGAR 0 0 0 0 0 0

EDWARDS 0 0 0 0 0 0

EFFINGHAM 0 0 0 0 2 2

FAYETTE 0 1 0 0 1 2

FORD 0 1 0 0 0 1

FRANKLIN 0 1 1 2 1 5

FULTON 0 0 0 0 0 0

GALLATIN 0 1 0 0 0 1

GREENE 0 0 0 0 0 0

GRUNDY 0 0 0 0 0 0

HAMILTON 0 0 0 0 0 0

HANCOCK 0 0 0 0 0 0

HARDIN 0 1 0 0 0 1

HENDERSON 0 0 0 0 0 0

HENRY 0 0 0 0 0 0

IROQUOIS 0 0 0 0 2 2

JACKSON 2 1 0 1 0 4

JASPER 0 0 0 0 0 0

JEFFERSON 3 1 0 2 1 7

JERSEY 0 0 0 0 0 0

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COUNTY 2001 2002 2003 2004 2005 Total

JO DAVIESS 0 0 0 0 0 0

JOHNSON 0 0 0 0 0 0

KANE 7 15 18 13 10 63

KANKAKEE 1 1 3 1 2 8

KENDALL 2 0 0 1 0 3

KNOX 1 0 2 1 0 4

LAKE 29 19 30 24 30 132

LASALLE 0 1 0 0 1 2

LAWRENCE 1 0 2 1 0 4

LEE 0 1 0 1 0 2

LIVINGSTON 0 1 0 0 0 1

LOGAN 0 0 0 0 0 0

MCDONOUGH 0 0 0 0 0 0

MCHENRY 3 7 0 7 2 19

MCLEAN 1 3 3 0 1 8

MACON 3 1 2 0 3 9

MACOUPIN 1 1 0 1 0 3

MADISON 5 2 5 6 7 25

MARION 0 0 0 2 0 2

MARSHALL 0 0 0 0 0 0

MASON 0 1 0 0 0 1

MASSAC 2 2 0 1 0 5

MENARD 0 0 0 0 0 0

MERCER 0 0 0 0 0 0

MONROE 0 0 0 1 0 1

MONTGOMERY 0 0 0 2 0 2

MORGAN 1 1 0 0 0 2

MOULTRIE 0 0 0 0 0 0

OGLE 1 0 0 0 0 1

PEORIA 2 8 3 0 3 16

PERRY 1 2 0 0 0 3

PIATT 0 1 0 0 0 1

PIKE 0 1 0 0 0 1

POPE 0 0 0 0 0 0

PULASKI 2 0 0 0 0 2

PUTNAM 0 0 0 0 0 0

RANDOLPH 1 0 0 1 0 2

RICHLAND 1 1 0 0 1 3

ROCK ISLAND 3 2 7 3 1 16

ST. CLAIR 4 11 8 5 2 30

SALINE 0 0 0 1 1 2

SANGAMON 13 1 1 5 2 22

SCHUYLER 0 0 0 0 0 0

SCOTT 0 1 0 0 0 1

SHELBY 0 0 0 0 0 0

STARK 0 0 0 0 0 0

STEPHENSON 0 0 1 1 0 2

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COUNTY 2001 2002 2003 2004 2005 Total

TAZEWELL 2 1 0 1 0 4

UNION 2 1 0 0 0 3

VERMILION 3 2 0 0 1 6

WABASH 0 1 0 1 0 2

WARREN 0 0 0 0 0 0

WASHINGTON 0 0 0 1 0 1

WAYNE 0 0 0 0 0 0

WHITE 0 2 0 0 0 2

WHITESIDE 0 0 0 0 0 0

WILL 12 16 9 15 18 70

WILLIAMSON 2 1 1 3 0 7

WINNEBAGO 9 7 3 9 7 35

WOODFORD 0 0 2 0 0 2

STATE-AT-LARGE 1 0 1 0 1 3

Table A2 Tuberculosis Cases and Rates (per 100,000 Population), Illinois, 2001-2005

Year 2001 2002 2003 2004 2005

Illinois Population: 12,419,293

707 (5.7)

680 (5.4)

633 (5.1)

569 (4.6)

596 (4.8)

Illinois Outside of Cook County Population: 7,042,552

189 (2.7)

168 (2.4)

171 (2.4)

170 (2.4)

143 (2.0)

Cook County Population: 5,376,741

518 (9.6)

512 (9.5)

462 (8.6)

399 (7.4)

453 (8.4)

Illinois Outside of Chicago Population: 9,523,279

329 (3.5)

298 (3.1)

294 (3.0)

261 (2.7)

263 (2.8)

Suburban Cook County Population: 2,480,727

140 (5.6)

130 (5.2)

123 (5.0)

91 (3.7)

120 (4.8)

City of Chicago Population: 2,896,014

378 (13.1)

382 (13.2)

339 (11.7)

308 (10.6)

333 (11.5)

1 Source: Census 2000 Summary File 1 Illinois, prepared by the U.S. Census Bureau, 2001

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Figure A1 TB Morbidity, Number of Cases, Illinois, 1980-2005

Figure A2 Distribution of Foreign-born Tuberculosis Cases, Illinois, 2001-2005

020406080

100120140160180200

2001 2002 2003 2004 2005

DownstateCity of Chicago

0

200

400

600

800

1000

1200

1400

1600

180019

80

1981

1982

1983

1984

1985

1986

1987

1988

1989

1990

1991

1992

1993

1994

1995

1996

1997

1998

1999

2000

2001

2002

2003

2004

2005

Illinois Ill. Excluding Cook County Suburban Cook County Ill. Excluding Chicago City of Chicago

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Table A3 Number of Foreign-born Tuberculosis Cases (% of total cases), Illinois, 2001-2005 Year 2001 2002 2003 2004 2005 Total

Illinois 36.6% (259/707)

38.9% (265/680)

43.1% (273/633)

40.4% (230/569)

44.8% (267/596)

40.6% (1,294/3,185)

Illinois Outside of Cook County

52.9% (100/189)

50.6% (85/168)

60.2% (103/171)

59.7% (101/170)

61.5% (88/143)

56.7% (477/841)

Cook County 31.1% (161/518)

35.1% (180/512)

36.8% (170/462)

46.7% (127/399)

39.5% (179/453)

34.9% (817/2,344)

Illinois Outside of Chicago

55.0% (181/329)

57.4% (171/298)

62.2% (183/294)

59.0% (154/261)

63.1% (166/263)

59.2% (855/1,445)

Suburban Cook County

58.6% (82/140)

66.2% (86/130)

65.0% (80/123)

58.2% (53/91)

65.0% (78/120)

62.7% (379/604)

City of Chicago 20.9% (79/378)

24.6% (94/382)

26.6% (90/339)

24.0% (74/308)

30.3% (101/333)

25.2% (438/1,740)

Table A4 Tuberculosis Cases, by Race/Ethnicity, Illinois, 2001-2005

2001 (%)

2002 (%)

2003 (%)

2004 (%)

2005 (%) Total

Total 707 680 633 569 596 3,185

White, Non-Hispanic 129 (18.2)

128 (18.8)

93 (14.7)

88 (15.5)

80 (13.4)

518 (16.3)

Black, Non-Hispanic 279 (39.5)

246 (36.2)

231 (36.5)

188 (33.0)

218 (36.6)

1,162 (36.5)

Hispanic 149 (21.1)

152 (22.4)

147 (23.2)

160 (28.1)

138 (23.1)

746 (23.4)

American Indian or Alaskan Native

5 (0.7)

3 (0.4)

4 (0.6)

2 (0.4)

2 (0.3)

16 (0.5)

Asian 145 (20.5)

149 (21.9)

154 (24.3)

125 (22.0)

151 (25.3)

724 (22.7)

Native Hawaiian or Pacific Islander1 NA NA 1

(0.2) 1

(0.2) 2

(0.3) 4

(0.1)

Multiple Races Indicated2 NA NA 2 (0.3)

5 (1.1)

5 (0.8)

12 (0.4)

Unknown 0 (0.0)

2 (0.3)

1 (0.2)

0 (0.0)

0 (0.0)

3 (0.1)

1 Native Hawaiian or Pacific Islander was included in Asian before 2003. 2 Multiple race reporting was not possible with the pre-2003 RVCT.

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Table A5 Tuberculosis Cases, by Race/Ethnicity, Illinois, 2005

Total Cases

White, Non-

Hispanic (%)

Black, Non-

Hispanic (%)

Hispanic(%)

American Indian or Alaskan Native

(%) Asian (%)

Native Hawaiian or Pacific Islander

(%)

Multiple Race

Indicated (%)

Unknown (%)

Illinois 596 80 (13.4)

218 (36.6)

138 (23.1)

2 (0.3)

151 (25.3)

2 (0.3)

5 (0.8)

0 (0.0)

Illinois Outside of Cook County

143 32 (22.4)

22 (15.4)

37 (25.9)

0 (0.0)

52 (36.4)

2 (1.4)

0 (0.0)

0 (0.0)

Cook County 453 48

(10.6) 196

(43.3) 101

(22.3) 2

(0.4) 99

(21.9) 0

(0.0) 5

(1.1) 0

(0.0) Illinois Outside of Chicago

263 52 (19.8)

52 (19.8)

61 (23.2)

0 (0.0)

98 (37.3)

0 (0.0)

0 (0.0)

0 (0.0)

Suburban Cook County

120 20 (16.7)

30 (25.0)

24 (20.0)

0 (0.0)

46 (38.3)

0 (0.0)

0 (0.0)

0 (0.0)

City of Chicago 333 28

(8.4) 166

(49.8) 77

(23.1) 2

(0.6) 53

(15.9) 0

(0.0) 5

(1.5) 0

(0.0)

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Table A6 Tuberculosis Cases, by Age Group, Illinois, 2001-2005 Age Group

Total Cases All

Ages

0-4 (%)

5-14 (%)

15-24 (%)

25-44 (%)

45-64 (%)

65+ (%)

2001 707 31 (4.4)

14 (2.0)

68 (9.6)

259 (36.6)

216 (30.6)

119 (16.8)

2002 680 25 (3.7)

19 (2.8)

76 (11.2)

226 (33.2)

199 (29.3)

135 (19.9)

2003 633 25 (4.0)

19 (3.0)

71 (11.2)

228 (36.0)

182 (28.8)

108 (17.0)

2004 569 21 (3.7)

19 (3.3)

54 (9.5)

206 (36.2)

174 (30.6)

95 (16.7)

2005 596 22 (3.7)

24 (4.0)

63 (10.6)

203 (34.1)

180 (30.2)

104 (17.5)

Total 3,185 124 (3.9)

95 (3.0)

332 (10.4)

1,122 (35.2)

951 (29.9)

561 (17.6)

Table A7 Tuberculosis Cases, by Age Group, Rates per 100,000 Population, Illinois, 2001-2005

Age Group Rates per 100,0001 0-4 5-14 15-24 25-44 45-64 65+

2001 3.5 0.8 3.9 6.8 8.1 7.9 2002 2.9 1.0 4.4 6.0 7.5 9.0

2003 2.9 1.0 4.1 6.0 6.8 7.2

2004 2.4 1.0 3.1 5.4 6.5 6.3

2005 2.5 1.3 3.6 5.3 6.7 6.9 2000

Population1 876,549 1,834,955 1,744,845 3,795,544 2,667,375 1,500,025 1 Source: Census 2000 Summary File 1 Illinois, prepared by the U.S. Census Bureau, 2001

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Table A8 MDR1 and Isoniazid2 Drug Resistance in Culture Positive Cases, Illinois, 2001-2005 Year 2001 2002 2003 2004 2005

INH Resistant

7.56%(41/542)

2.7%(14/523)

3.6%(23/480)

4.8% (21/411)

6.4% (29/451)

Illinois

MDR Resistant

0.73%(4/542)

1.1%(6/523)

0.5%(3/480)

1.2% (5/411)

0.0% (0/451)

INH Resistant

9.92%(13/131)

1.6%(2/122)

3.5%(6/171)

7.8% (10/119)

10% 11/110

Illinois Outside of Cook County

MDR Resistant

0%(0/131)

0.8%(1/122)

0.6%(1/171)

1.6% (2/119)

0.0% 0/110

INH Resistant

6.82%(28/410)

3.0%(12/401)

3.7%(17/462)

3.6% (11/292)

5.3% 18/341

Cook County

MDR Resistant

0.97%(4/410)

1.2%(5/401)

0.4%(2/462)

1.0% (3/292)

0.0% 0/341

INH Resistant

8.01%(19/237)

3.5%(8/229)

4.8%(14/214)

5.5% (11/188)

7.7% (16/209)

Illinois Outside of Chicago

MDR Resistant

0.42%(1/237)

1.3%(3/229)

0.7%(2/214)

1.5% (3/188)

0.0% (0/209)

INH Resistant

5.71%(6/105)

5.6%(6/107)

6.5%(8/87)

1.4% (1/72)

5.1% (5/99)

Suburban Cook County

MDR Resistant

0.95%(1/105)

1.9%(2/107)

0.8%(1/87)

1.4% (1/72)

0.0% (0/99)

INH Resistant

7.21%(22/305)

2.0%(6/294)

2.7%(9/266)

4.3% (10/223)

5.4% (13/242)

Chicago

MDR Resistant

0.98%(3/305)

1.0%(3/294)

0.3%(1/266)

0.9% (2/223)

0.0% (0/242)

1 Isolates resistant to at least isoniazid and rifampin. 2 Isoniazid resistant cases may also be resistant to other drugs, while being susceptible to rifampin.

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Table A9 Tuberculosis Cases, by Directly Observed Therapy (DOT), Illinois, 2000-2004

DOT

Year Total Cases

Cases Eligible

for DOT1

Totally Self Administered

(%)

Totally DOT (%)

Both DOT and SA

(%) Total (%)

Unknown or Missing

(%)

2000 743 718 258

(35.9) 375

(52.2) 77

(10.7) 452

(62.9) 8

(1.1)

2001 707 684 209

(30.5) 368

(53.8) 106

(15.5) 474

(69.3) 1

(0.1)

2002 680 653 212

(32.4) 346

(53.0) 96

(14.7) 442

(67.6) 0

(0.0)

2003 633 605 148

(24.5) 327

(54.1) 127

(21.0) 454

(75.0) 3

(0.5)

2004 567 546 132

(24.2) 299

(54.8) 105

(19.2) 404

(74.0) 0

(0.0)

Total 3,330 3,206 959

(29.9) 1,405 (43.8)

511 (15.9)

2,226 (69.3)

12 (0.4)

1 Includes cases alive at diagnosis with an initial drug regimen of one or more drugs prescribed Table A10 HIV and TB, 2001-2005

Year Total Cases

Total Cases Ages 25-44 years

(%) Valid Response1

(%)

Total HIV Positive2

(%)

2001 707 257

(36.3) 165

(64.2) 37

(14.4)

2002 680 226

(33.2) 157

(69.4) 30

(13.2)

2003 633 228

(36.0) 162

(71.0) 28

(12.2)

2004 569 206

(35.9) 162

(78.6) 22

(10.7)

2005 596 202

(33.8) 171

(84.2) 23

(11.2)

Total 3,185 1,119 (35.1)

817 (73.0)

140 (12.5)

1 Valid response includes (0) negative, (1) positive or (2) indeterminate. 2 Positive results are based on either medical documentation or patient history.

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Table A11 Tuberculosis Cases, by Risk Factors, 2001 – 2005

Year Total Cases

Correctional Facility1

(%) Homeless2

(%)

Long Term Care Facility3

(%)

Injection Drug Use4

(%)

2001 707 18

(2.5) 23

(3.2) 22

(3.1) 17

(2.4)

2002 680 20

(2.9) 31

(4.5) 17

(2.5) 16

(2.3)

2003 633 7

(1.1) 23

(3.6) 9

(1.4) 6

(1.0)

2004 569 10

(1.8) 22

(3.9) 13

(2.3) 6

(1.1)

2005 596 14

(2.4) 23

(3.9) 11

(1.9) 5

(0.8)

Total 3,185 69

(2.2) 122 (3.8)

72 (2.3)

50 (1.6)

1 Resident of correctional facility at time of diagnosis

2 Homeless in past 12 months 3 Resident of long term care facility at time of diagnosis 4 Injection drug use in past 12 months Table A12 Tuberculosis Cases by Verification Criteria, 2001-2005 Year Total

Cases1 Culture

Confirmed Smear

Positive Clinical

Definition Provider

Diagnosis 2001 703 561

(79.8) 10

(1.4) 90

(12.8) 42

(6.0) 2002 679 531

(78.2) 5

(0.7) 110

(16.2) 33

(4.9) 2003 630 484

(76.8) 5

(0.8) 89

(14.1) 52

(8.3) 2004 567 430

(75.8) 11

(1.9) 71

(12.5) 55

(9.7) 2005 596 452

(75.8) 5

(0.8) 54

(9.1) 85

(14.3) Total 3,175 2458

(77.4) 36

(1.1) 414

(13.0) 267 (8.4)

1 Current data as of May 4, 2006 was used to populate this table. Row totals do not reflect the total number of counted cases for that year, but rather reflect the number of currently known cases at that time.

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Table A13 Tuberculosis Cases by Country of Origin, 2001-2005 Country of Origin Total 2001 2002 2003 2004 2005 Mexico 374 75 77 73 79 70 India 265 52 61 53 43 56 Philippines 174 29 32 44 37 32 China 43 8 5 12 8 10 Vietnam 42 15 6 8 5 8 Poland 41 7 8 6 7 13 Korea, Republic Of 33 5 10 6 5 7 Pakistan 27 9 9 2 3 4 Nigeria 18 1 5 9 1 2 Ecuador 17 3 2 4 5 3 Ethiopia 17 0 6 2 1 8 Bosnia And Hercegovina 15 6 3 3 2 1 Guatemala 15 5 1 4 2 3 Thailand 11 4 1 2 1 3 Korea, Dem. Peoples Rep 9 3 3 3 0 0 Honduras 8 4 1 0 1 2 Burma 7 2 3 1 0 1 Haiti 7 0 1 3 0 3 Peru 7 0 0 1 3 3 Somalia 7 1 1 0 1 4 All Other Nations 165 31 32 40 27 35

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Appendix B - References Tuberculosis Case Definition for Public Health Surveillance see CDC reference: http://www.cdc.gov/nchstp/tb/surv/surv2002/PDF/AppendixB.pdf Recommendations for Counting Reported Tuberculosis Cases see CDC reference: http://www.cdc.gov/nchstp/tb/surv/surv2002/PDF/AppendixC.pdf

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Appendix C – TB Regions TB Regions are divided as follows: Northern TB Region includes all of IDPH Rockford and West Chicago Region except Grundy, Kankakee and Will counties. Central TB Region includes all of IDPH Peoria and Champaign Region plus Grundy, Kankakee, and Will counties from W. Chicago region and; excludes Macon, Moultrie and Shelby counties. Southern TB Region includes all of IDPH Edwardsville and Marion Region including Macon, Moultrie and Shelby counties from Champaign Region.